Azithromycin or sumamed which is better. The choice of antibiotic for the treatment of diseases of the respiratory and ENT organs. Professional medical publications concerning the use of Sumamed

• Respiratory Organs
• Genitourinary system
• Gastrointestinal tract
• Skin and soft covers.

Contraindications

Pregnancy and lactation

Mode of application

Side effects

1. Gastrointestinal organs

1. urinary system

3.Circulatory system

1. Nervous system

1. Allergy

Overdose

Price

"Sumamed"

Indications for use

• Respiratory Organs
• Skin and soft tissues
• acne
• Genital organs

Contraindications

Pregnancy and lactation

Dosage and administration

Side effects

1. Gastrointestinal tract

1. Allergy

1. Urogenital system.

1. The cardiovascular system

1. Nervous system

Overdose

Price

Active substance

Contraindications

Side effects

For kids

The crux of the matter is this. The child drank sumamed for 2 days, outwardly the condition worsened (t-ra stopped going astray, general well-being worsened). A decision was made to change the antibiotic, after a tablet of flemoclav after 2 hours - voila, t-ra is normal, lasts half a day, the child is cheerful, etc. And what worked? Finally sumamed earned? Somehow I can’t believe that “one tablet” of flemoclav is enough to significantly improve the situation in a couple of hours. I sit and think, drink flemoclav now for a week, as the doctor ordered, or what? I would be glad to hear the opinion of doctors.

PS: I communicate with the doctor via SMS, because I myself sit without a voice, I can’t call, so I would discuss my doubts with the pediatrician, of course. I'll talk as the voice cuts through

Often patients wonder how interchangeable drugs Flemoxin Solutab and Summamed are, how to use them correctly and when. The answers to the most frequently asked questions are in our article.

Are Flemoxin and Sumamed different names for the same drug?

No. Although the drugs have similar indications, they belong to different groups. antibacterial agents. And therefore they have different pharmacological properties, side effects and contraindications.

The active substance of Flemoxin is amoxicillin, a representative of penicillins. It is a synthetic drug with good tolerability and proven effectiveness against many pathogens. Today it is produced in the form of tablets, as well as syrup for young children.

It is worth noting that Flemoxin is a generic, it is produced by the Dutch pharmaceutical company Astellas Pharma. For a long time in therapeutic practice namely antibiotics penicillin group were the drugs of choice for a variety of bacterial pathologies.

Sumamed is the original and historically the first preparation of azithromycin, the most important representative of macrolides.

It is produced by the Croatian company Pliva in the form of tablets of various dosages and syrup for babies. After the spread of strains of bacteria with high resistance to penicillins, scientists and doctors turned their attention to other groups of drugs - including macrolides.

My child has angina. Which of the drugs is better to take?

Only a qualified doctor should choose which antibiotic for children (Sumamed or Flemoxin Solutab) should be prescribed. It is he who must determine which of the drugs is better to give advantage based on many criteria. It should be remembered that self-medication often leads to the development of unexpected complications without improvement. general condition child.

Although patients often have a question, Flemoxin Solutab or Sumamed, which of them is better, it is impossible to give an unambiguous answer to it.

• whether this antibiotic was taken in the past (if so, when exactly), whether there was a good positive effect from taking it;
• the presence of a child allergic reactions to receive beta-lactam antibiotics (penicillins, cephalosporins, carbapenems, monobactams);
• the severity of the general condition of the child;
• results of bacteriological research with the study of the sensitivity of microflora to individual antibiotics.

The main advantage of Sumamed is the low resistance of the bacterial flora. Therefore, it often often gives a result where penicillins are useless.

Sumamed is given an advantage when serious condition a child who is allergic to penicillins, has not responded to Flemoxin treatment, or has recently used amoxicillin preparations.

The doctor prescribed me Flemoxin, but I have a package of Sumamed at home. Can it be used?

Flemoxin has a wider spectrum of action on pathogenic microorganisms than Sumamed, so it can be used for a large number of diseases. However, with many the following pathologies these drugs are almost completely interchangeable:

• bronchitis;
• pneumonia;
• otitis;
• pharyngitis;
• sinusitis;
• tonsillitis;
• chlamydia pathologies of the urinary tract and reproductive system;
• inflammation of soft tissues and skin (erysipelas, phlegmon);
• Lyme disease (initial stage).

In this case, the difference in the regimen of taking drugs should be taken into account. Since azithromycin is able to accumulate in inflamed tissues of the body, it is enough to take it at the same time only once a day.

Reception of Flemoxin must be repeated 2-3 times, since it is quickly excreted by the kidneys from the blood. Also, after the last dose, Sumamed remains in therapeutic concentrations in tissues for up to 72 hours. Therefore, the course of therapy with this antibiotic is shorter by 2-3 days.

The final decision to replace Flemoxin with Sumamed should be made by the attending physician.

Which drug has fewer side effects?

Many patients are afraid of antibacterial drugs because, in their opinion, they have a large number of side effects and can allegedly seriously harm their health. But the dangers of antibiotics are greatly exaggerated. Especially if we are talking about penicillins or macrolides.

Both groups of these antibacterial agents are well tolerated by most patients.

Their safety is also evidenced by the fact that the American FDA organization issued category B to both Flemoxin and Sumamed. This means that these antibiotics can be used during pregnancy, since there is no evidence of toxic effects on the fetus. They are also prescribed to patients during lactation and newborns.

When using Flemoxin, allergic reactions are most often observed. varying degrees severity (from rash and dyspeptic symptoms to anaphylactic shock). Therefore, it is imperative that before the first use of an antibiotic, a test for hypersensitivity to it is carried out. Sometimes the development of diarrhea, abdominal pain, drowsiness, inhibition of hematopoiesis, anemia, transient nephritis, headaches, and drowsiness are noted.

Allergy to Sumamed is very rare. However, when using it, cases of dizziness, disorders digestive system, parasthesia, transient increase in the concentration of liver enzymes and creatinine, anxiety and nervousness of patients.

When is Flemoxin prescribed instead of Sumamed?

The main limitation of the appointment of Sumamed for children, in addition to a narrower spectrum of action, are contraindications. It should not be used in the following patient conditions:

• chronic liver pathologies with reduced functional ability (insufficiency);
• heart rhythm disturbances (especially with blockades);
• myasthenia gravis (azithromycin acts as an antagonist of drugs that are used to treat it);
• if necessary, the prevention of rheumatism (lack of data on effectiveness);
• electrolyte disturbances (especially hypokalemia);
• in the presence of allergic reactions to the intake of other macrolides.

Why can Sumamed be taken once a day, but Flemoxin needs three?

Sumamed has the ability to accumulate in inflamed tissues, in which its concentration can be 20-30 times higher than the amount of antibiotic in the blood. This is due to its unique pharmacological properties.

Azithromycin molecules penetrate into immune cells and migrate with them in the eyes of inflammation.

The ability to stay in bound state allows them to be excreted from the body by the kidneys much more slowly. Therefore, with many pathologies (bronchitis, pharyngitis, tonsillitis), the course of treatment lasts only 3 days.

"Flemoxin Solutab": instructions for use

"Flemoxin" is used for infectious and inflammatory diseases:

• Respiratory Organs
• Genitourinary system
• Gastrointestinal tract
• Skin and soft covers.

Contraindications

Restriction on the use of "Flemoxin Solutab" - a strong susceptibility specifically to this drug or other antibiotics.

The main active ingredient of the drug "Flemoxin Solutab" is amoxicillin - it is a half-synthetic antibiotic. A diverse spectrum of action has made it such a popular substance that is part of many drugs. Amoxicillin also has very good bioavailability.

Pregnancy and lactation

Apply "Flemoxin" during pregnancy and lactation is permissible only with the permission of a doctor. At the same time, the doctor advises amoxicillin only if the chances of recovery from the prescribed drug are higher than the possible risks and side effects.

Mode of application

It is necessary to take the medicine "Flemoxin Solutab" inside. Specific doses are set by the doctor based on the stage of the disease and the age of the patient.

With mild to moderate disease, you should drink 600 mg twice a day. This rule also applies to children over 10 years old. Children from 3 to 10 years old should take 400 mg twice a day. Babies 1 to 3 should take 250 mg twice a day. Crumbs up to a year can also be treated with this drug. Their dose should be 30-60 mg per day. It should be divided into several steps.

If the disease is of high severity and progresses, you should drink the medicine three times a day. If the disease is chronic, it is possible to increase the dose of the drug taken, but only after consulting a specialist.

Side effects

Like every medicine, Flemoxin has some side effects. They can come from various organs human body.

The reaction of the body may be as follows:

1. Gastrointestinal organs

Perhaps a change in the taste of products, vomiting, diarrhea for several days.

1. urinary system

May react with the development of nephritis. However, such cases are extremely rare.

3.Circulatory system

It is possible that there will be prerequisites for anemia, the formation of blood clots, neutropenia.

1. Nervous system

Deviations or disturbances in the human nervous system during all days of using Flemoxin were not found.

1. Allergy

The medicine can cause allergic reactions on the skin. In particular, rashes.

Overdose

An overdose of the drug "Flemoxin" threatens with nausea, vomiting and diarrhea. This may take up to 7 days. Sometimes there may be failures in the water-electrolyte balance of the human body.

AT similar situations it is necessary to immediately wash the stomach, take activated charcoal and laxatives based on salts.

Price

The price of the drug ranges from 250-350 rubles. It depends on the pharmacy where you make the purchase. Tablets 125, 250, 500 mg differ in cost by about 100 rubles.

"Sumamed"

Indications for use

Sumamed is prescribed for infectious and inflammatory diseases:

• ENT organs (pharyngitis, tonsillitis, otitis media, sinusitis)
• Respiratory Organs
• Skin and soft tissues
• acne
• Genital organs
• Caused by high susceptibility to azothromycin.

Contraindications

It is undesirable to use "Sumamed" for people who have high sensitivity to this type of antibiotics or failures in the activity of the liver and kidneys.

Pregnancy and lactation

Pregnant and lactating women should not take Sumamed. But, it is possible only with the permission of the doctor if the chances of a cure are higher than potential danger. In this case, it is not necessary to take the medicine for the entire course, but only for a few days.

Dosage and administration

Tablets should be taken orally, once a day. The medicine in the form of capsules and suspensions must be drunk a couple of hours before or after a meal.

Babies up to six months should take the medicine as an oral suspension.

For diseases of the respiratory tract and soft tissues of the body, take 500 mg once a day. The course of treatment is 3 days.

Children are required to take "Sumamed" following the calculation of 10 mg / kg of body weight. Drink once a day for 3 days.

Side effects

To begin with, I must say that side effects occur only in 1% of people taking Sumamed.

Since each organ in the human body is unique, the reaction to the drug will be different.

1. Gastrointestinal tract

You may face jaundice, bloating, nausea, vomiting, constipation, gastritis, decreased appetite during the first days of taking the medicine.

1. Allergy

Skin rashes may appear (especially in young children).

1. Urogenital system.

Development of vaginal candidiasis and nephritis.

1. The cardiovascular system

You may experience chest pain or a fast heartbeat.

1. Nervous system

Headaches, dizziness, drowsiness and anxiety throughout the days of using the drug make themselves felt. Children often have headaches.

In addition, itching, urticaria, conjunctivitis and fatigue may appear.

Overdose

An overdose of the drug "Sumamed" can lead to: vomiting, nausea and diarrhea. In some cases, temporary hearing loss is possible.

In case of overdose, consult a doctor immediately. He will cleanse the stomach. Should be consumed Activated carbon and laxatives, salt medicines during all days of treatment.

Price

Tablets of 500 mg cost 480-500 rubles. Tablets of 125 mg cost about 300-350 rubles.

Which is better: Flemoxin or Sumamed Price

We can definitely say that it varies in the same range.

Active substance

The indisputable "plus" of the first medicine is that the active substance in it is amoxicillin. It is a very popular antibiotic. He has high performance absorption. If amoxicillin gets into your body in excessive amounts, it will only lead to the standard symptoms of poisoning. The active substance "Sumamed" does not have such a number of advantages.

Contraindications

They are the same too. Allergy sufferers and pregnant or lactating women should take the drug only after consulting a doctor.

Side effects

Both drugs can cause dangerous side effects. Still, it is preferable to choose the first drug considered - "Flemoxin". Its side effects are milder compared to those of Sumamed.

"Sumamed" contains less harmful chemical additives which may lead to negative consequences.

For kids

Both medicines can be used for children, but only after consulting a doctor.

It is impossible to say unequivocally which of the drugs is better. Much depends on the specific disease and the degree of its development. "Sumamed" is more suitable for mild forms of the disease, and "Flemoxin" is prescribed for critical situations. In any case, you should not make the decision yourself. It is better to consult a doctor who, after weighing all the factors, will make the right decision.

"What better Sumamed or Flemoxin? - this is a frequently asked question at the appointment with a specialist, but only the body can give an answer. Each person is individual, and only his own body can say and know what is best for him.

Both drugs belong to the category of antibacterial agents, but to different groups. Despite this, they can be used to treat the same diseases. To find out what is best for a particular patient, you can compare Sumamed and Flemoxin Solutab. The following is Comparative characteristics both dosage forms.

The active ingredient in Sumamed is azithromycin. It is sold in tablet form, and has three dosages: 125 mg, 250 mg and 500 mg. For young children, the manufacturer has created a powder for making a suspension. Sumamed is a representative of the Macrolides and Azalides group.

Indications for use Sumamed

Sumamed is used to treat infectious diseases, which are accompanied by a pronounced inflammatory process. It is used to treat pathologies of organs and body systems, namely:

• pyelonephritis, urethritis, cystitis;
• rashes on the skin, and especially acne;
• boils, carbuncles, purulent hydradenitis, erysipelas;
• otitis, pharyngitis, tonsillitis, sinusitis;
• bronchitis, pneumonia.

Dosage and rules of admission

Sumamed tablet is intended for internal use should be drunk once a day. The medicine must be taken a few hours before meals, or after. For a child, the antibiotic is used in the form of a suspension.

In the presence of pathologies of the upper and lower respiratory tract, Sumamed is taken at a dosage of 500 mg once a day. The treatment lasts for three days.

Powder for the preparation of a children's suspension, diluted at the rate of 10 mg per 1 kg of body weight of the baby. It is used once a day, for three days.

Contraindications

Women who are expecting a baby and breastfeeding should refrain from taking this medicine. In some situations, the doctor may allow the use of this antibiotic. It should not be taken on its own.

Adverse reactions

Side effects in the treatment of azithromycin are extremely rare, but if you take Sumamed and Flemoxin at the same time, then the risk negative reactions increases significantly. But this combination is very rare.

When using Sumamed, the following side effects are observed:

• From the genitourinary system: inflammation of the kidneys, thrush;
• From the side of cardio-vascular system: pain in the chest area, tachycardia;
• From the side of the central nervous system: presyncope, headache, anxiety states, sleep disorders;
• From the gastrointestinal tract: increased gas formation, jaundice, nausea, sometimes turning into vomiting, loss of appetite, inflammation of the gastric mucosa;
• Rashes on the skin are associated with an allergy to the drug. Most often seen in young patients.

Some patients develop hives, itching all over the body, general weakness, fatigue and conjunctivitis.

The most popular analogue of the drug Sumamed is Azimed.

Flemoxin Solutab

The active substance of the drug Flemoxin Solutab is amoxicillin. The manufacturer produces the drug in the following dosages: 125 mg, 250 mg, 500 mg and 1000 mg. The tablet is intended for dissolution in the oral cavity.

Only a doctor can prescribe Flemoxin, since all antibiotics are dispensed from a pharmacy on a prescription form. He is a representative of the "Semi-synthetic penicillins" group.

Indications for the use of Flemoxin

According to the instructions for use, Flemoxin Solutab is used for such pathologies:

• tonsillitis, pharyngitis, otitis media, tonsillitis, sinusitis;
• abscesses, boils, erysipelas, phlegmon;
• pancreatitis, gastritis;
• cystitis, urethritis.

Dosage and rules of admission

Flemoxin Solutab tablets are intended for internal use, the dosage of the drug is selected by the doctor, it depends on the disease, as well as the age of the patient.

At lung pathologies and moderate a dose of 600 mg twice a day is well suited, it is intended for adult patients, and children over 10 years old. Children from 3 to 10 years old should take 400 mg 2 times a day. From 1 to 3 years - 250 mg 2 times a day. For children under 1 year of age, the daily dose ranges from 30 mg to 60 mg.

For severe illnesses single dose Flemoxin does not change, but the number of doses per day increases, there are three of them.

Contraindications

Flemoxin should not be taken by patients with individual intolerance to the components of the drug.

With extreme caution, Flemoxin should be taken during pregnancy and lactation. It is used only on the recommendation of the attending physician.

Adverse reactions

As mentioned above, drinking Sumamed and Flemoxin together is not recommended, since the number of possible side effects increases significantly. Since Sumamed, Flemoxin has its own list of negative reactions. These should include:

• From the genitourinary system: inflammation of the kidneys;
• From the gastrointestinal tract: change taste sensations, indigestion, nausea, sometimes turning into vomiting;
• From the hematopoietic system: anemia, the formation of blood clots;
• Allergic rashes on the skin.

You can replace Flemoxin with such drugs: Ospamox, Amoxil, Gramox, Amosin.

Sumamed or Flemoxin

According to information circulating on Internet forums, most patients believe that Sumamed is more strong antibiotic than its competitor Flemoxin. Do not rely on unreliable sources of information, since only the attending physician can know which is better - Sumamed or Flemoxin Solutab.

Since each organism is individual, and the disease proceeds in different ways. Not worth doing self-treatment you should always follow your doctor's instructions.

Found an error? Select it and press Ctrl + Enter

Modern third-generation macrolides are increasingly becoming the drugs of choice, especially in childhood in ENT practice. They differ from other groups in a prolonged effect and ease of use, as a rule, they are well tolerated. Klacid or Sumamed as representatives of the same group, but with different active ingredients, are selected depending on the type of infection and pathogen. Let's compare their available forms and compositions, and most importantly, we will analyze the results clinical research to find out what and under what diseases it is better to choose.

Antibacterial drugs are used only as prescribed by a doctor.

Klacid is an English brand based on a macrolide antibiotic. clarithromycin. The entire line of forms is presented:

• two types of tablets
• solution for drip intravenous administration,
• and soluble powder for children's suspension.

In tablet form, Klacid is divided into two types:

Croatian Sumamed contains azithromycin as the main component. More effective than popular antibiotics penicillin series(Flemoxin Solutab, Amoxicillin) for the treatment of angina, although somewhat inferior in spectrum of action to their modified versions with the addition of clavulanic acid (Flemoclav,). But compared with clarithromycin from Klacid has a number of advantages:

• in all forms, it acts for a long time
• most often used in a short course of 3-5 days (for sinusitis and diseases of the lower respiratory tract, at the discretion of the doctor, it can be extended)
• there is a dispersible form with a high dose of azithromycin (convenient for a single dose, for example, with chlamydial infection)
• in tablets is better suited for use in childhood - below the threshold age limit, and powder for suspensions is available in different flavors (raspberry, banana, strawberry).

Among the shortcomings can be noted:

• the need to space out meals. Sumamed is properly taken one hour before or two hours after meals;
• lack of a form for infusion administration, unlike Klacid;
• lower activity with the opponent when gastrointestinal infections, in particular for the destruction of Helicobacter pylori as part of a complex with bismuth preparations (De-Nol, Ulcavis), PPI (omeprazole, lansoprazole) and an additional antibiotic. This point is disputed, recent studies have shown that azithromycin in a similar combination is not inferior to clarithromycin and even better tolerated.

If Sumamed and Klacid are compared in terms of the width of the list of indications for use, then they are very similar, but their effectiveness in the same disease varies.

What is better for diseases of the upper respiratory tract?

In 380 adult patients with acute otitis, sinusitis, streptococcal tonsillitis or pharyngitis, the effectiveness of standard doses of clarithromycin (Klacid) for a 10-day course and azithromycin (Sumamed) for a three-day course was compared. It was found that at 10-14 days, the overall clinical efficacy was the same in each group with a satisfactory result (cured or improved) in 96% and 95% of patients, respectively. 7-8% of people from both groups complained of side effects from the digestive system. It was concluded that a three-day course of azithromycin was as effective and well tolerated as a ten-day course of clarithromycin.

With pyogenic streptococcus in children

Throat diseases caused by staphylococcal infection most often do not require the appointment of antibacterial drugs. However certain types streptococci must be destroyed. Thus, the detection of beta-hemolytic streptococcus after bakposev or a rapid test requires the appointment of antibiotics. In Italy, a comparison was made with the participation of 174 children who were found to have this pathogen. One group was treated with azithromycin for three days, the other with clarithromycin for 10 days. In both groups, a positive result was achieved. In the control test 10 days after the start of therapy, streptococcus was not detected in 93% in the azithromycin group and in 86% in the clarithromycin group. In this way Sumamed is better suited to combat pyogenic streptococcus.

What is better for diseases of the lower respiratory tract?

In a study of 510 patients with acute bronchitis and pneumonia were obtained following results: 10 days of clarithromycin (250 mg - 2 times a day) and 3 days of azithromycin (500 mg - 1 time per day) gave a similar therapeutic effect. In laboratory tests for complete bacteriological elimination, Klacid is slightly stronger. In practice, resolution or improvement occurred in 95-100% and both treatment strategies were found to be equally effective.

conclusions

Antibiotics do not apply to self-selection drugs, first of all, the on-site doctor should determine Klacid or Sumamed will be better in each case. World experience shows that with almost similar effectiveness, Sumamed outperforms its competitor in terms of the convenience of the regimen and the duration of the course and can be the drug of choice in childhood. Klacid SR, although it makes it possible to take it once a day, but like the usual one, it requires up to two weeks of therapy.

In terms of the cost of treatment, the Croatian drug is also more profitable and will cost from one and a half to two times cheaper.

Antibiotics have become an integral part of modern medicine, they help fight pathogenic bacteria that often mutate and cause irreparable damage. human body. Domestic pharmacology offers a wide range of antibiotics that affect microbes in one way or another. Each class affects a certain type of bacteria, and only a specialist can figure out which antibiotic to treat a particular disease. However, this does not prevent people from wondering what is the difference between one type of antibiotic and another.

Definition

Sumamed(active ingredient azithromycin) is one of the first representatives of the class of macrolides, modern look broad spectrum antibiotics. This is the name of the original drug developed by the specialists of the Croatian pharmaceutical company Pliva in 1980. Azithromycin is the international non-proprietary name of Sumamed, however, this name is also used by a number of drugs that are analogs of Sumamed.

Azithromycin- this is a generic or generic, in other words, a copy or analogue of the original drug. Today, this drug can be found in various forms and dosages, and the reason for this is its popularity. Many companies are striving to launch their Sumamed analogue on the market, as it is in demand among medical workers and gets good feedback from patients.

Comparison

The unique properties of azithromycin, the active ingredient that is part of Sumamed, led to the emergence of a large number of analogues (generics). The drug has bactericidal activity against a large number of pathogenic bacteria that produce proteins. Sumamed affects pathogens such as pneumococcus, Staphylococcus aureus and pyogenic, some types of streptococci, chlamydia, legionella, as well as gonorrhea and syphilis pathogens. In domestic medical practice, the drug is used to treat pharyngitis, tonsillitis, sinusitis, otitis and other infections of the upper respiratory tract caused by the above microorganisms. The dosage of the drug is calculated by the therapist at the reception, depending on the state of the body and on general flow illness.

Generic drugs are much cheaper for their companies, because for the most part they do not pass clinical and laboratory tests, but only copy the studies that were conducted for the original drug. Ideally, the composition of generics should completely repeat original composition drug, however, different manufacturing technology and some other features of production do not allow to achieve complete identity. In some cases, the composition of the tablet shell or the concentration of the active substance can vary greatly, and therefore it is completely unclear how the human body can react to this. Not surprisingly, generics are several times cheaper than the original drug.

Findings site

1. Sumamed is the original drug, Azithromycin is a generic.
2. Sumamed costs 3-4 times more than Azithromycin.
3. Sumamed necessarily passed clinical and laboratory studies, Azithromycin - no.

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Manufacturers of antibacterial agents offer a great variety of drugs with different trade names. At the same time, the composition of some drugs is absolutely identical. A variety of generics and substitutes, supplemented with minor components and additives, are increasingly filling the shelves of pharmacy chains. Today you will find out which analogue of "Klacida" can be chosen. It should be clear right away that self-medication can be dangerous. Especially doctors do not welcome the use of antibiotics on their own whim.

The antibiotic is available in three forms. At your discretion, you can choose tablets, injections or suspension. The latter is more commonly used in children. The active substance of the drug - clarithromycin - refers to antimicrobials broad spectrum of action, macrolides. The drug "Klacid" (tablets and suspension) is prescribed for bacterial lesions of the upper and lower respiratory tract, ENT organs, and also the skin. It is important that the microorganisms that caused the infection are sensitive to the active substance. So, for example, gram-negative bacteria that decompose lactose are resistant to the claimed drug.

Apply "Klacid" 250-500 mg twice a day. The duration of treatment varies from 5 to 14 days. For children, the drug is prescribed in an individual dosage, depending on age and body weight, under the supervision of a doctor. It is contraindicated to use the medicine in case of hypersensitivity, violation renal function, pregnancy and lactation.

"Klacid" (suspension) - reviews say - has a pleasant taste. It is convenient that it can be given to children with milk. Such a drug costs about 400 rubles per 60 ml. Medicine in tablets (10 pieces of 250 mg) can be purchased for 600 rubles. Infusions - patients say - are prescribed quite rarely. The cost of an ampoule with a dosage of 500 mg is 650-700 rubles.

An analogue of "Klacida" can be found cheap. Many consumer reviews turn out to be negative only because of the price of the antibiotic. Not every person can afford to buy pills for almost 1000 rubles. There is a need to find more available drug. This was Clarithromycin. It contains the same active ingredient as the original product. However, the cost of tablets is about 250 rubles. At the same time, there will be 14 pills in the package, not 10. Unlike the expensive American drug, this medicine is produced in Russia.

The indications of analogues are the same. The difference is that the domestic medicine can also be used to treat ulcers. digestive tract, but in combination with additional medicines. This medication is not used in the same cases as its predecessor. It is unacceptable to give it to children under 12 years old. If you choose to purchase Klacid or Clarithromycin for a child, then the first medicine in the form of a suspension will have an advantage.

What else can be found analogous? "Klacid" can be replaced with "Ekozitrin" tablets. Such a drug costs from 200 rubles. Each tablet contains 500 mg of clarithromycin and excipients. A medicine is prescribed for bacterial lesions of the ear, nose, throat, bronchi and lungs. It is used to treat skin infections and stomach ulcers. It is contraindicated to use "Ekozitrin" with kidney failure, sensitivity, hypokalemia. The remaining contraindications coincide with the declared drug. The duration of treatment, unlike previous analogues, is 10-14 days. In some cases, it is advisable to take an antibiotic for six months.

"Klacid" or "Sumamed" - which is better? This question often arises in people who are at least a little versed in medicine. These two drugs are compared because they are both macrolides. The substances that make up the composition are different. The component of "Sumamed" is azithromycin. This medicine, as stated, is available in the form of tablets and suspensions. A solution for internal administration is produced, but it is practically not in demand. The cost of packaging "Sumamed" is approximately 500 rubles. The drug is prescribed for the same purpose as Klacid. Also, this analog can be used to treat genital infections.

If the doctor prescribes Klacid or Sumamed, which is better to choose? The last medicine is very popular. Also, its plus is that you need to take only one tablet per day. Unlike "Klacid", "Sumamed" is unacceptable to use during meals and even more so to mix it with milk.

If you have intolerance to the active ingredients of the Klacid drug, then you can choose a substitute with a different composition, for example, based on amoxicillin. This active substance belongs to the penicillin series of antibiotics. A popular representative is Flemoxin tablets. There are also trade names for drugs: Amoxicillin, Amosin, Ospamox, Ecobol and others. "Klacid" or "Flemoxin" - which is better to choose? Last drug has its advantages and disadvantages:

• "Flemoxin" should be taken three times a day, and "Klacid" - two;
• penicillin antibiotic often provokes digestive disorders;
• "Flemoxin" - dispersible tablets (can be dissolved in water);
• This analogue costs about 350 rubles. for 20 pcs.;
• "Flemoxin" helps with gastrointestinal diseases caused by microorganisms sensitive to it;
• This medicine can be used during pregnancy and to treat babies.

"Klacid" - tablets and suspension that can provoke an allergy. With this outcome, the medication is often replaced with antibiotics related to the cephalosporon series, a new generation. You can replace the claimed agent with drugs: Suprax, Cephalexin, Ceftriaxone, Cefatoxime, and so on.

These antibiotics inhibit the reproduction of bacteria by damaging their wall. Doctors say that only Cefalexin is absorbed from the gastrointestinal tract. Therefore, the rest of the drugs are prescribed for intravenous and intramuscular administration. If taken orally, then severe irritation mucous membranes of the stomach and intestines. The cost of the drug "Cefalexin" (16 tablets) is no more than 150 rubles. Affordable price also important to the consumer.

If you decide to take an analogue of Klacida, then you must definitely discuss this with your doctor. All the described drugs have a wide range of antibacterial action. Perhaps this is the only thing that unites them. Cost, scheme of admission, tradename and the composition is what makes them different. Some medications are often prescribed to children and expectant mothers ("Flemoxin"), others are prohibited drugs in pediatrics.

Reviews about antibiotics are different. The fact is that the same medication can have completely different effects on people. For some, the medicine helps quickly and effectively. For others, the antibiotic is effective, but at the same time it causes frustration. digestive function. There are cases when medications caused severe allergies which only made the patient feel worse. It is impossible to say unequivocally that this drug is good, and the other is bad. Therefore, to determine the best analogue you need to know the medical history of the patient who is going to take the medication.

Today you learned what the antibiotic "Klacid" is. Suspension is becoming increasingly rare for consumers. Therefore, they are forced to look for another medicine that can be used for children. Before using any substitute, read the instructions for use, paying special attention to contraindications, recommended dosage and possible adverse reactions. Good health!

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When a doctor prescribes antibiotics, he selects the most effective and safe drugs for a particular disease. However, patients often ask the question “Which is better: Klacid or Augmentin?” Sometimes they ask to explain the difference between similar antibacterial agents.

Antibiotics are medicines that kill bacteria. They are used in many diseases caused by these microorganisms.

Antibacterial drugs belong to different groups. The most used among them are the following:

• Penicillins.
• Cephalosporins.
• Macrolides.
• Fluoroquinolones.
• Tetracyclines.
• Aminoglycosides.
• Polymyxins.

Each group of drugs has its own spectrum of action. In most cases, it is quite broad and includes both Gram-negative and Gram-positive bacteria.

Very often, doctors prescribe antibiotics from the group of penicillins and macrolides - for example, amoxiclav (Augmentin) and clarithromycin (Klacid).

Despite the fact that the spectra of action of these drugs are similar, there are certain differences between them. In addition, they are differently tolerated and differ in the list of side effects.

It is these features that guide the specialist who prescribes this or that antibiotic.

In order to understand the doctor's actions, it is necessary to present the indications and contraindications for prescribing a particular drug, as well as its action, metabolism and route of excretion.

Perhaps the most prescribed drug from the group of penicillins is Augmentin. It is recommended by therapists and pediatricians, surgeons and gastroenterologists, urologists.

This antibiotic is successfully used to treat pregnant women and nursing mothers. This category of patients has its own limitations of use, but it is Augmentin that is their drug of choice.

The popularity of the antibiotic is associated with several factors:

1. High efficiency of the drug.
2. Rapid onset of action.
3. Ease of use.
4. Good tolerance.
5. Injectable and tablet forms.
6. Possibility of use in childhood.
7. Beta-lactamase resistance.

Since penicillins have been used in medical practice for a long time, many bacteria have developed protection against them. Some have become resistant, making them immune to the bactericidal action of antibiotics. And others produce special substances - enzymes that can destroy and inactivate the drug. They are called beta-lactamases and are most effective against penicillins.

Some antibiotics in this group are themselves resistant to the action of bacterial enzymes, but they have other disadvantages - for example, a narrow spectrum of action, insufficient efficacy, rapid elimination from the body.

To give the antibiotics of this group resistance, they began to be combined with other drugs that have this property. This is how amoxiclav (Augmentin) appeared. Due to the presence of clavulanic acid in its composition, bacteria cannot destroy the drug and reduce its activity.

The scope of Augmentin is quite extensive.

Augmentin can be used for various pathologies. This is due to its spectrum of action.

Most gram-negative and gram-negative microbes are sensitive to this drug. Most often it is prescribed for diseases respiratory system, as well as ENT organs. In addition, it is widely used in diseases of the genitourinary system (pyelonephritis, cystitis) and the digestive tract (acute cholecystitis).

Surgeons prescribe Augmentin for diseases of the skin (erysipelas) and soft tissues.

Amoxiclav is the drug of choice for angina and pneumonia.

Augmentin in most cases is prescribed for pneumonia as a first-line antibiotic. Bacteria are sensitive to it causing pneumonia(pneumococci).

Such monotherapy is usually successful and does not require the appointment of additional drugs. However, this is true only for mild forms of the disease.

Sometimes doctors combine amoxiclav with azithromycin. This combination is effective against gram-negative, gram-positive microbes, as well as mycoplasmas and chlamydia.

In moderate and severe forms, amoxiclav is administered intravenously.

Angina is called inflammation of the tonsils. However, unlike ordinary tonsillitis, this term often refers to a disease caused by beta-hemolytic streptococcus.

Angina is fraught toxic effect microbes on the kidneys and hearts. Its frequent complication is glomerulonephritis, the result of which may be renal failure.

Also, angina leads to the development of a special pathology - rheumatism. The disease begins with damage to the joints, but the heart suffers most of all. The result of untreated tonsillitis is a variety of acquired defects - stenosis and insufficiency of the mitral, aortic, tricuspid valves.

Beta-hemolytic streptococcus is sensitive to antibiotics of the penicillin group. That is why Augmentin is prescribed so often for angina.

Amoxiclav is produced in different dosages. This allows it to be used both in pediatric practice and for the treatment of adults. In addition, the content of the active substance also determines the frequency of taking tablets (or performing injections).

Augmentin can be taken 2 or 3 times a day. The course of treatment averages 5-7 days, if necessary, lasts up to ten days.

The parenteral route of drug administration is intravenous injections. It is chosen for severe forms of the disease.

The injections help the medicine to go directly into the bloodstream, which provides rapid achievement effect.

When treating with amoxiclav, there is no need to adhere to a specific diet, but the drug should be taken at regular intervals. This will create the desired concentration of the antibiotic in the blood.

Amoxiclav very often causes undesirable reactions from the gastrointestinal tract. Patients report stomach discomfort, nausea and even vomiting. Diarrhea is a very common side effect.

It occurs in many patients receiving this antibiotic, and is the reason for the diagnosis of "dysbacteriosis".

However, this condition resolves on its own without any therapy after the antibiotic is discontinued. Only in rare cases develops more serious disease- antibiotic-associated colitis requiring serious treatment.

Clarithromycin is a macrolide antibiotic. The following microorganisms are susceptible to it:

• Staphylococci and streptococci.
• Listeria, Neisseria and Moraxella.
• Haemophilus influenzae.
• Legionella.
• Mycoplasmas.
• Chlamydia.
• Mycobacteria.
• Clostridia.
• Spirochetes.
• Campylobacter.

Clarithromycin is resistant to the action of beta-lactamases, these enzymes are not able to inactivate it. However, some strains of staphylococci cannot be treated with this antibiotic. These are oxalin- and methicillin-resistant strains.

In relation to some microorganisms, clarithromycin is able to exhibit a bactericidal effect.

In pharmacies, clarithromycin is known by the following names:

• Klacid;
• Clubax;
• Klabel;
• Clamed;
• Clarimax;
• Clarite;
• Claritro Sandoz.

Indications for the appointment of clarithromycin usually indicate diseases of the respiratory system and ENT organs. These include:

1. Bronchitis.
2. otitis media.
3. Sinusitis (purulent frontal sinusitis, sinusitis, ethmoiditis, pansinusitis).
4. Pneumonia (especially its atypical forms).

In addition, this antibiotic is used for erysipelas, impetigo, furunculosis. It is also prescribed for diseases caused by mycobacteria.

There are certain limitations in Klacid therapy. So, it is not recommended during pregnancy, especially in the first trimester, and during lactation.

When treated with this antibiotic, there is high risk development of candidiasis - thrush. In this regard, doctors often prescribe a parallel intake of antifungal drugs - for example, Fluconazole.

Clarithromycin should not be used in patients with severe renal insufficiency.

Among the side effects of this drug is liver damage - drug-induced hepatitis. It is an indication for discontinuation of clarithromycin and correction of therapy.

The safety profile of clarithromycin is known. Adverse reactions are rare and most often unpleasant symptoms from the gastrointestinal tract.

Patients may complain about:

• Change in taste.
• Decreased appetite.
• Anorexia (rare).
• Nausea and vomiting.
• diarrhea.
• Abdominal pain.

These manifestations usually do not require special treatment and disappear on their own after discontinuation of the drug. However, in some cases, doctors have to change antibacterial drug.

Rarely, clarithromycin can be toxic to the blood system, causing agranulocytosis and thrombocytopenia.

On the background long-term treatment an antibiotic from the macrolide group, patients noted insomnia, increased anxiety and irritability, headaches, dizziness, hearing loss.

In addition, treatment with this drug can cause the development of a variety of allergic reactions.

But in most cases, clarithromycin therapy is well tolerated. It is usually given as a tablet that is taken twice a day.

This antibiotic is approved for use in children. However, up to 12 years of age, doctors recommend using an antibiotic in the form of a suspension.

It is difficult for the patient to determine which drug is better - clarithromycin or amoxiclav. That is why the choice of an antibiotic is always the prerogative of the attending physician, who takes into account the nature of the disease, contraindications and the individual characteristics of the patient.

elaxsir.ru

Vilprafen Solutab is the trade name for the macrolide antibiotic josamycin, which is used primarily to treat bacterial pathologies of the upper respiratory tract. Over time, it was also found that this drug acts much more widely, which led to significant expansion indications for use.

Vilprafen Solutab has a good bacteriostatic effect due to the ability to inhibit the work of the 50S subunit of the ribosome of microbes. This results in the inability to reproduce further. pathogenic bacteria, as well as reducing their resistance to the body's immune response.

It acts on Staphylococcus, Streptococcus, Neisseria, Pneumococcus, Corynebacterium, Mycoplasma, Chlamydia, Treponema and Rickettsia.

The pharmacological features of josamycin are special. Molecules of the drug are well absorbed at oral intake. Vilprafen Solutab is not used for intramuscular or intravenous administration. Antibiotic particles accumulate precisely in inflamed tissues, where their concentration can exceed the amount of the drug in the blood several times. Vilprafen is excreted from the body mainly by the kidneys in an unchanged state, which makes it possible to use it for infections of the genitourinary system.

Vilprafen Solutab is prescribed for the following conditions:

• tracheitis;
• acute and chronic bronchitis;
• community-acquired pneumonia without complications;
• sinusitis;
• otitis;
• pharyngitis;
• tonsillitis (including diphtheria);
• dental bacterial pathologies;
• urethritis;
• cystitis;
• chlamydia;
• gonorrhea;
• bacterial processes in soft tissues.

When using Wilprafen, side effects are rarely observed. Sometimes there are allergic reactions of varying severity (however, much less often than when prescribing beta-lactam antibiotics).

Cases of a transient increase in the concentration of bilirubin and liver enzymes in the peripheral blood, the development of toxic hepatitis, hearing loss, general fatigue and the appearance of edema of the lower extremities.

The drug has a rather small list of contraindications, which includes individual intolerance to the components of the drug, impaired renal function, pregnancy and lactation in women.

Also, neonatologists do not advise prescribing Vilprafen during the neonatal period of a child.

Vilprafen Solutab is prescribed for adults at 500-1000 mg 2-3 times a day, depending on the severity of the pathology. For children, the dosage of the antibiotic must be individually calculated based on their age and body weight. Their usual daily dose is 50 mg/kg. The duration of the course of treatment is from 5 to 14 days.

Azithromycin

Azithromycin, as Vilprafen analogue, is an antibacterial agent from the group of macrolide antibiotics. The drug is a representative of the azalide subclass, which introduces several features in pharmacological characteristics antibiotic.

The drug has a bacteriostatic effect, like josamycin. The mechanism of action of these drugs is also identical. However, the spectrum of sensitivity to azithromycin is somewhat narrower. In this antibiotic, the ability to accumulate in inflamed tissues of the body is more pronounced, in which its therapeutic concentration lasts up to 72 hours. This reduces the frequency of administration and the course of antibiotic treatment.

As with other analogues of Vilprafen, indications for the appointment of azithromycin are almost identical. Azithromycin - as one of the safest and most effective antibiotics, today it is included in the protocols for the treatment of all antibacterial pathologies of the respiratory system and ENT organs.

He is given an advantage in case of ineffectiveness of penicillins, or the presence of hypersensitivity to beta-lactam drugs (in addition to penicillins, this also includes cephalosporins, monobactams, carbapenems).

Azithromycin is also included in combination therapy with peptic ulcer for the eradication of Helicobacter pylori infection.

You can not prescribe azithromycin in the following conditions:

• individual intolerance to the drug;
• liver failure;
• the presence of a congenital tendency to tachyarrhythmias of the heart.

During pregnancy, azithromycin is prescribed in cases where it cannot be replaced with a drug with a safer profile. In renal insufficiency, it is necessary to carefully select the dosage of the drug based on indicators glomerular filtration. At the same time, it is desirable to monitor the concentration of the antibiotic in the blood plasma.

Assign azithromycin to adults at 500 mg 1 time per day. Most pathologies require a 3-day course of therapy, but if necessary, it can be continued. For children, a special form of the antibiotic has been developed in the form of a syrup, which also simplifies the dosage of the drug.

If we are talking about analogues of Vilprafen, then it is necessary to say about Klacid. This drug also belongs to the group macrolide antibiotics. Its active ingredient is clarithromycin. Like other representatives of this class of medicines, Klacid has a bacteriostatic effect. But unlike josamycin, this drug does not effective action for causative agents of urogenital infections.

However, Klacid inhibits almost the entire spectrum of mycoplasma and Helicobacter pylori infections.

In the body, clarithromycin accumulates in the affected tissues, but is excreted much faster than azithromycin. At the same time, the drug shows the greatest effectiveness with neutral acidity. Therefore, for the treatment of Helicobacter pylori infection, it must be combined with drugs that would lower the production gastric juice(proton pump inhibitors are most suitable).

AT current recommendations highest value Clarithromycin is used as a treatment for Mycobacter pylori, Legionella and Helicobacter pylori. It is also used in bacterial infectious processes of the respiratory system and ENT organs.

Klacid is contraindicated in the presence of next states in the patient:

• allergies to drugs of the macrolide group;
• ventricular tachyarrhythmias or a high risk of their development;
• hypokalemia;
• liver failure;
• concomitant use of ticagrelor after myocardial infarction;
• use of colchicine.

The most common side effects when taking Klacid are:

• transient increase in the concentration of bilirubin and liver enzymes in the blood plasma;
• allergic reactions of varying severity;
• accession of a secondary bacterial, viral or fungal infection;
• development of cardiac tachyarrhythmia;
• hematopoiesis suppression (with clinical symptoms anemia, internal or external hemorrhages, secondary infections);
• toxic effect on the central nervous system(headache, dizziness, paresthesia);
• functional disorders of the digestive system (nausea, vomiting, feeling of heaviness in the abdomen, loss of appetite, diarrhea).

During lactation and pregnancy, the drug is not recommended.

The course of treatment depends on the etiology of the bacterial process. With Helicobacter pylori infection, the course of treatment lasts at least 14 days, with most diseases of the respiratory system 3-7 days, and with mycobacterial infection - from 10 days.

Amoxicillin is an antibacterial agent belonging to the group of synthetic penicillins. Unlike penicillin, this drug has a pronounced bactericidal effect. Its molecules are capable of disrupting the integrity of the cell membranes of pathogenic pathogens, which leads to their death and lysis.

The drug actively acts on staphylococci, streptococci, pneumococci, corynebacteria, Haemophilus influenzae, clostridia, listeria, salmonella, shigella, coli, Proteus, Klebsiell, Moraxell. This allows the use of antibiotics for a wide range of bacterial infections respiratory and digestive systems.

When taken orally, the drug is partially absorbed. Therapeutic concentration of amoxicillin is maintained for 3-4 hours after ingestion. This is due to the 3-time frequency of antibiotic use per day.

Amoxicillin is used for bacterial pathologies of the respiratory system (tracheitis, bronchitis, community-acquired pneumonia), ENT organs (otitis, sinusitis, pharyngitis, tonsillitis), intestinal infections (salmonellosis, shigellosis), cholecystitis, urethritis, cystitis and for the prevention of complications after surgical interventions .

When prescribing amoxicillin, more often than other analogues, allergic reactions occur (rash with severe itching, dyspeptic disorders, Quincke's edema or anaphylactic shock). Therefore, before prescribing, it is imperative to clarify with the patient whether he has previously had hypersensitivity reactions to beta-lactam antibiotics (penicillins, cephalosporins, monobactams and carbapenems).

In addition, the following side effects occur:

• sleep disturbance;
• headache and dizziness;
• dyspeptic disorders;
• toxic hepatitis and yellowness of the skin;
• oppression of hematopoiesis.

Despite the presence of these side effects, amoxicillin is considered a safer antibacterial drug than macrolides.

It is allowed to be used as a substitute for Vilprafen during pregnancy. However, it also has its drawback - many strains of bacteria have developed resistance to its action. What is better in each specific situation should be decided by a qualified doctor.

Amoxicillin is prescribed in the form of tablets for adults and syrup for children under 6 years of age.

med-antibiotics.ru

The use of such an antibacterial drug as Klacid does not always produce the expected effect, and it becomes necessary to look for its analogues. Scientists around the world note an increase in cases of multiple resistance of pathogens of infectious diseases to antibiotics. Miscellaneous groups antibacterial agents have their advantages and disadvantages in relation to various microorganisms, which, of course, must be taken into account, and then compared similar drugs and choose the most suitable one. After all, in each specific situation, the choice of antibiotic is individual. Since in order to replace klacid, suprax, amoxiclav or other drugs from the macrolide group are most often purchased, it is they that should be compared with each other.

S umamed is a drug from the group of antibiotics based on active component azithromycin. The medicine is included in the group of macrolides and azolides, produced in the Republic of Croatia. In some cases, it becomes necessary to choose an analogue of Sumamed at a cheaper price - the list includes eight drugs, including Russian ones.

The possibility of replacing with a medicine with an identical active substance or with a medicine from the same pharmacological group is determined only by a doctor. At the same time, he takes into account the pathogen pathological process, tolerability of the active substance, the presence of concomitant complications.

The effectiveness of Sumamed is due to the action of the active ingredient - azithromycin, which contributes to a wide range of effects. This substance is able to suppress the production of proteins of microbial cells, slow down growth and reproduction. pathogenic microorganisms.

The use of azithromycin in high concentration has a bactericidal effect. The drug affects gram-positive, gram-negative, aerobic and intracellular microflora. It should be taken into account that a number of microorganisms can show resistance to azithromycin.

In most cases, Sumamed demonstrates effectiveness in relation to:

• Gram-positive aerobes: penicillin-sensitive Staphylococcus aureus and pneumococcus, pyogenic streptococcus.
• Gram-negative aerobes: Haemophilus influenzae, Haemophilus, Legionella pneumophila, Moraxella catharalis, Pasteurella multicide, gonococcus.
• Anaerobes: Clostridia perfringens, Prevotella.
• A number of other microorganisms: chlamydia, mycoplasma, borrelia.
• Azithromycin can pass through cell membranes, which determines its effectiveness against intracellular pathogens.

After administration, the active substance is rapidly absorbed and begins to be distributed in the body. In the future, phagocytes move the active substance to the place of development infectious process where azithromycin is released.

Release form

The drug is presented on the pharmaceutical market in the following dosage forms:

• Tablets for oral administration of 125, 500 mg.
• Powder for suspension for internal use 100mg/5 ml.
• Capsule for oral use.

The selection of the dosage form, as well as the dosage, is carried out by the doctor, taking into account the age of the patient and individual characteristics his body.

Indications for use and contraindications

According to the instructions, the use of Sumamed is recommended for patients when diagnosing:

• Pharyngitis, tonsillitis, otitis, sinusitis.
• Acute and exacerbation chronic bronchitis and pneumonia.
• Secondarily infected dermatoses, impetigo, erysipelas.
• The initial stage of Lyme disease, accompanied by erythema migrans.
• Infectious diseases of the urinary organs provoked by chlamydia: urethritis, cervicitis.

• Individual intolerance to azithromycin, erythromycin and other substances from the macrolide group.
• Phenylketonuria.
• Severe liver and kidney dysfunction.
• The need for the simultaneous use of ergotamine and dihydroergotamine.

The drug is not intended for self-medication, before use, a doctor's consultation and diagnostics are required.

Dosage

The drug is intended for internal reception, once every 24 hours.

• Capsules and suspension should be used 60 minutes before or 120 minutes after the main meal.
• Taking pills does not depend on eating.
• Patients older than six months are prescribed a suspension or tablets of 125 mg.

The dosage of the drug depends on the indications for the use of the drug and the age of the patient:

When is the selection of an analogue necessary?

If it is necessary to select a replacement, it is recommended to consult with your doctor without fail. take into account clinical picture diseases, tolerability of the active substance and the therapeutic effect of the recommended treatment regimen.

The selection of an exact structural analogue with the same active substance may be required if the cost of the original drug does not suit the patient.

When medicine fails to do the right thing therapeutic result the doctor reviews the treatment regimen and may prescribe an antibacterial drug with a different active ingredient or replace it with drugs from other pharmacological groups.

With intolerance to the active component and the development of undesirable adverse reactions They are also considering a replacement.

List of cheaper analogues

The cost of Sumamed in December 2017 is:

• Tablets 500 mg, 3 pcs. - from 470 rubles.
• Tablets 250 mg, 6 pcs. - from 340 rubles.
• Capsules 250 mg, 6 pcs. - from 480 rubles.
• Dispersible tablets 1000 mg, 3 pcs. - from 1000 rubles.
• Dispersible tablets 1000 mg, 1 pc. - from 465 rubles.

Pharmacies have cheaper Russian analogue Sumameda - Azithromycin in the form of capsules and tablets for internal use. Depending on the manufacturer of the drug, the cost for 6 capsules of 250 mg is from 120 rubles. for 3 tablets of 500 mg - from 130 rubles.

Scroll inexpensive drugs With similar action, for treatment respiratory diseases includes the following medications:

• AzitRus - from 30 rubles.
• Hemomycin - from 135 rubles.
• Augmentin - from 250 rubles.
• Azitrox - from 190 rubles.
• Foemoxin solutab - from 250 rubles.
• Amoxiclav - from 120 rubles.
• Zi-Factor - from 200 rubles.

When choosing a replacement, it is necessary to pay attention not only to the difference in cost, but also to the dosage of the drug and its dosage form(capsules, tablets, powder for suspension).

Sumamed or Azithromycin - which is better?

Azithromycin is a domestic analogue of Sumamed with an identical active ingredient, which can be purchased at pharmacies by prescription. The drug is presented in the form of tablets and capsules for oral administration, there is no release form in the form of powders for the preparation of a suspension.

Preparations differ in the composition of excipients, as well as cost.

Sumamed or Hemomycin

Hemimycin is the exact structural generic of Sumamed, which differs only in the manufacturer and in the composition of additional substances. Both drugs are manufactured in accordance with the required quality standards: the tablets are coated film sheath, despite the fact that the analog is much cheaper.

A number of clinical studies indicate that more expensive substitutes are better tolerated by patients, because during the production process all the necessary conditions and drugs comply with the latest technological standards.

Sumamed or Suprax

The composition of the drug Suprax includes another active ingredient - cefixime, the drug is produced by the Jordanian company Khimka Pharmaceuticals. The drug belongs to the group of 3rd generation cephalosporin antibiotics, while Sumamed is an antibacterial drug from the macrolide group.

Indications for use in antibiotics are similar, Suprax is also used in the complex therapy of pharyngitis, tonsillitis, sinusitis, bronchitis, otitis media, uncomplicated gonorrhea and infections of the urinary system.

Sumamed or Amoxiclav

Antibacterial drugs of the penicillin series, to which Amoxiclav belongs, have a weaker therapeutic effect. The expediency of prescribing a particular medication is determined by the doctor, taking into account the indications for admission and concomitant symptoms. The active components of Amoxiclav are amoxicillin in combination with clavulanic acid.

Since the active ingredients of drugs differ, the selection of a suitable drug is carried out taking into account the sensitivity of pathogenic microorganisms to the active ingredient, and not just because one is cheaper and the other is more expensive. The doctor may begin treatment with the use of antibiotics of the penicillin series, and if Amoxiclav is ineffective, the use of Sumamed is recommended.

Sumamed or Augmentin

Both drugs differ in composition, country of origin and method of application. The active components of Augmentin are amoxicillin in combination with clavulanic acid.

The drug belongs to the antibiotics of the penicillin series - this is the exact structural analogue Amoxiclav, with the same mechanism of action, only cheaper.

As for the method of application, the course of treatment with Sumamed is shorter - from 3 days, while average duration use of Augmentin - from 1 week. The drug should not be taken continuously for more than 14 days.

Sumamed or Flemoxin Solutab

Flemoxin is a substitute for Sumamed only for pharmacological group. The composition of drugs is different: the active substance of Flemoxin is amoxicillin, which belongs to the group of penicillins.

The drug can provoke the development of allergic reactions, therefore, before starting treatment, a thorough history taking is required in order to identify hypersensitivity reactions to penicillin.

What to choose - Sumamed or Klacid?

Klacid is an antibacterial drug from the macrolide group, however, the active substance differs from Sumamed: the composition of tablets and powder for suspension includes active ingredient clarithromycin.

Sumamed or Vilprafen

Vilprafen is a more modern and effective antibacterial drug from the macrolide group. It has a more extensive list of indications for use than Sumamed.

If necessary, Vilprafen can be used in the treatment of pregnant women with chlamydial infections. The active substance of the drug is josamycin. The duration of the use of tablets is from 5 days and longer, under the supervision of specialists.

Sumamed's analogs for children

Children's analogues of Sumamed are selected taking into account the age of the child and the indications for the use of the medicine.

Any of the above can be used in the treatment of younger patients age groups: some medicines administered to patients under 1 year of age. The physician may recommend the use of soluble tablets, and suspensions for internal use.

Let's summarize

The selection of a suitable medicine can only be carried out by a doctor, after an internal examination of the patient, and according to the results of a bacteriological study. Self-selection and taking antibiotics is unacceptable, since all drugs act after a certain period of time, when the active substance accumulates in the cells to the desired concentration.

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