What uric acid should a man have. Non-medical causes of high uric acid. How to pass the analysis so that it is reliable

Uric acid- a substance formed as a result of the metabolism of purines. Purines are part of DNA and are found in large quantities in animal tissues.

When accumulated in large quantities uric acid causes gout and urolithiasis.

The normal concentration of uric acid changes greatly with age. So, in children, it is only 140-340 micromoles per liter of blood; in adult men under 65 years old - 220-420 µmol / l, in men after 65 - up to 500.

In men involved in sports, the concentration of uric acid can be 10-20% higher than in all other people. It is not considered a pathology.

Why can the rate be higher than normal?

There are only two reasons for the increase in uric acid in the blood:

• First, it is an increased content of purines in food. Purines chemical substances, which are part of deoxyribonucleic acid (DNA). They are found in large quantities in animal foods.
• The second reason is metabolic diseases, which lead to the fact that uric acid is simply not excreted from the body, despite the fact that a normal amount is formed in the body.

Of course, in some cases, both causes can overlap, and then the level of uric acid rises much more. This usually happens in older people who have metabolic problems with age, and the diet remains the same, rich in animal foods.

In addition to food, some medications can also affect the amount of purines in the body, e.g. diuretics.

In order not to cause an increase in uric acid, the amount of foods containing many purines will have to be limited, and medications should be canceled.

What can be downgraded?

A reduced amount of uric acid in the blood indicates disorders of purine metabolism, which can be caused by the following reasons:

• Lack of purine food consequences of dieting or starvation;
• Poor absorption of purine due to liver disease, overdose of certain drugs;
• Genetic predetermined or arising in the embryonic period of development of metabolic disorders, hereditary diseases.

With a lack of parin in the blood, you should increase the consumption of foods that contain a lot of these substances.

Table 1. Foods high in purines.

It is important that when cooking food, food loses its purines, which pass into the broth. Therefore, if you drain the broth, then the concentration of purines will drop sharply.

Causes of deviation from the norm

The most common cause of an increase in uric acid in the blood is age-related changes that lead to metabolic disorders. It is no coincidence that it is the elderly who most often suffer from gout and kidney disease. If uric acid is elevated in young boys and girls, or in middle-aged people, the cause is probably wrong diet, in which there is too much animal food, little water and juicy vegetables.

You should also know that increase in acidity(reducing the pH) of the blood increases the content of uric acid in it, and alkalization (increasing the pH) leads to a decrease in the amount of this substance.

How to lower the level of the substance?

With a high concentration of uric acid in the blood, apply complex methods treatments that are aimed at both reducing the concentration of acid and eliminating the consequences of its presence.

Primarily, to lower uric acid in the blood uses a diet consisting mainly of herbal products, and very few animal products containing purines.

A very important role in reducing the concentration of uric acid in the blood is played by the intake of fluids and food rich in water (various vegetables, watermelons, etc.). The liquid not only dilutes the uric acid in the blood, but also allows you to eliminate the consequences of an increase in its concentration. So, due to the passage of large volumes of water through the kidneys, they begin to dissolve urate stones.

If the cause of the increase in uric acid was a metabolic disorder, weight loss helps.

For medical treatment, various pharmacological agents such as xanthine oxidase inhibitors and non-steroidal anti-inflammatory drugs.

Consequences of deviations

A level of uric acid in the blood that is significantly higher than normal is called hyperuricemia. This is enough dangerous state which can cause gout or kidney failure. This happens due to the fact that uric acid accumulates in the joints or kidneys, begins to form microscopic crystals.

If the number of these crystals in the joints is large enough, the joints completely lose their ability to bend and unbend, respond with every movement in severe pain, which makes a person unable to work. This is how gout develops. The first sign of this disease is with pain in the joints of the 1st toe. Then inflammation begins in the joints of this finger.

If gout is not treated, it begins to affect other joints: pain in the heel, ankle, wrists, shoulders, hip joint, spine.

Uric acid crystals begin to accumulate in the kidneys, gradually increases as all the new microscopic crystals coalesce into one large one. Thus, stones form in the kidneys, which cause pain and damage to the tissues of the kidney. Uric acid stones are called levels, they can have a very complex shape, which is why they cause damage to the kidneys. big harm something to me of other kinds.

Conclusion

Thus, to reduce the amount of uric acid, you need to follow vegetarian diet and consume more water. Also suitable are juicy fruits, vegetables and gourds, which contribute to flushing the kidneys.

If the level of uric acid is low, this indicates lack of purines in the body. To make up for the lack of these substances, eat more animal products.

Performs important functions in the body. However, if the indicators of the substance in the blood are higher than normal, it is necessary to urgently begin treatment, since this condition is characterized not only by a deterioration in the patient's well-being, but also by the development of complications.

To normalize the level of acid, various medications and traditional medicine recipes. It is also mandatory for treatment to comply with general principles right image life, which contribute to the reduction of substances in the body.

Uric acid - what is it, its normal level

Uric acid is a substance that is produced as a result of metabolic process in the breakdown of purines digestive system. A substance is formed in It usually dissolves in the blood and enters the kidneys. In this case, uric acid is excreted during urination.

Among important functions this substance is excreted in the body:

• Antioxidant action, which is to protect cells from free radicals.
• Activation of adrenaline and norepinephrine, which affects normal functioning nervous system.
• Prevention of the development of cancer cells.
• Excretion from the body carbon dioxide with urine.

The amount of a substance in the blood depends on the age criterion, as well as on the gender of the person. The following indicators are normal levels:

• In men - from 210 to 420 micromoles per liter
• In women - from 150 to 350
• Children up to one month - up to 311
• Under the age of one year - from 90 to 372
• From one to fourteen years - from 120 to 320

The highest rate of acid at the norm is observed in male body. This is due to the fact that when physical work The body of a man needs frequent replenishment of the body with proteins.

To get accurate and reliable results you need to know how to properly prepare for the study. Experts recommend donating blood on an empty stomach. It is also important to exclude products containing great amount proteins, and alcoholic drinks. If a person takes any medications, this factor must be told to the doctor. It is advisable for people after forty-five years to undergo diagnostics annually.

Blood for research is taken from a vein. Uric acid is determined by blood serum. Usually, the results of the analysis can be obtained at the clinic the next day.

The main factors of increased level

Hyperuricemia - high levels of uric acid in the blood

The increase in the substance in the blood is influenced by physiological and pathological factors. The two main causes of higher than normal urinary levels are considered to be a violation of the production of a substance in the liver and improper excretion of it by the kidneys.

Uric acid rises in the following cases:

• Heavy physical exercise.
• Starvation long time.
• Protein diet.
• Long-term use of certain medications.
• The use of products that contain a large number of proteins.
• Alcohol abuse.

An increase in the substance is determined in the blood in such diseases:

• Pathologies in which the excretion of a substance in the urine is difficult.
• Diseases endocrine system(, acidosis).
• Hereditary diseases (Lesch-Nyhan syndrome, Hodgkin's disease).
• Psoriasis and others pathological conditions skin covers.
• Pathology of the liver (,).
• Infectious diseases(scarlet fever, tuberculosis, pneumonia).
• Hypovitaminosis (mainly vitamin B12 deficiency).
• Oncological diseases (most often leukemia, lymphoma).
• Allergic reactions.
• Arterial hypertension.
• High levels in the body and lipoproteins
• Hyperuricemia is considered an important sign for diagnosing gout.
• Uric acid can rise due to obesity and complications of pregnancy, for example, with toxicosis.

Signs of high levels of a substance in the blood

The following signs may indicate an increased content of uric acid in the body:

• Bad feeling.
• Back pain.
• High .
• Soreness in the joints.
• Indigestion.
• General weakness.

One of frequent signs hyperuricemia in adults is considered the occurrence of tartar and decreased performance. With an increase in the substance in the body, pain during urination is possible.

In children, hyperuricemia may be accompanied by enuresis, frequent pain in a stomach, neurological disorders. Diathesis spots are often observed in small patients.

Treatment Methods

First of all, treatment should be directed to the underlying disease that provoked the high level of uric acid. Therefore, only a specialist can prescribe medicines. If uric acid is elevated due to physiological reasons, then this condition does not need special treatment. Over time, the level will normalize on its own.

Usually, in order to lower uric acid in the body, the following groups of drugs are used:

• Drugs that remove uric acid from the blood. Probenecid is one of them.
• Medications that reduce the production of uric acid. Usually prescribed when complications begin to appear advanced level substances. These drugs include Colchicine, Allopurinol, Benzobromarone.
• Drugs that transfer a substance into the blood from the tissues and affect the intensity of its excretion in the urine. Effective from this group of drugs is Tsinkhoven.
• With hyperuricemia, diuretics such as Lasix, Mannitol, Furosemide, Sulfinpyrazole are often prescribed.

Other methods of lowering substances in the blood are:

• Plentiful drink. Drinking liquid contributes, as a result of which excess uric acid is excreted from the body. It is recommended to drink nine to fifteen glasses of plain water per day.
• Proper nutrition. Avoid foods that contain purines from your diet. Therefore, it is recommended to refuse organ meats, anchovies, beer, confectionery, white bread, smoked meats, legumes, drinks containing fructose. It is also important to limit your salt intake. It is advisable to eat fresh fruits and vegetables dairy products. Portions for hyperuricemia should be small, it is better to eat up to five times a day.
• Weight loss. It is recommended to increase physical activity, adhere to a certain diet. However, fasting must be avoided.

Useful video - Uric acid in the blood: causes and treatment

There are also recipes in alternative medicine that help normalize uric acid. Among such remedies, the most effective is the use of decoctions and tinctures from such medicinal plants inside:

• Sabelnik.
• Lingonberry (leaves).
• Collection of calendula chamomile and sage.
• Birch leaves.
• Lemon and garlic.

As an auxiliary medicine for high uric acid, it is recommended to take nettle juice. When using folk remedies, it is important to remember that they are not a panacea, but are used as helper method to the main treatment.

If uric acid is elevated in the body for a long time, this can lead to the development of serious conditions.

Often a high level of a substance in the blood leads to the occurrence of the following pathologies:

• Gout.
• Formation of stones in the kidneys and urinary tract.
• body intoxication.
• Ischemic disease.
• Myocardial infarction.
• Angina.
• Chronic arthritis.

Often, with a high content of uric acid in the body, lesions of the nervous system occur, against which migraines, sleep disorders, decreased vision, attacks of aggression occur.

The development of complications depends on the localization of the formation of sodium urates by uric acid. If crystals appear in the kidneys, diseases of this organ occur. With the deposition of urate in the joints, gout begins to progress and.

The balance of substances in the body determines the coherence of all systems and serves as a guarantee of health. With an increase in the amount of certain substances and compounds, the system fails. It helps to detect deviations and disturbances in the functioning of organs and systems. various analyzes, surveys. The beginning of diagnosis, as a rule, begins with biochemistry. The body contains uric acid. The norm in men varies depending on the age group. This is one of the parameters of biochemistry, which is often used in medicine.

The action of a substance in the body

Uric acid or uric acid plays important role in metabolic process. This low molecular weight nitrogenous substance is a derivative product of protein, which is subsequently excreted from the body. The process involves vital important organs: liver (cleavage) and kidneys (excretion). Failure of these systems causes the accumulation or decrease in the level of uric acid in the patient's blood. A normal level of a substance in the patient's blood means that the functions of the liver and kidneys work without disturbance. In the presence of clinical symptoms and complaints from the patient, the doctor prescribes additional tests and surveys.

Nitrous acid acts as an antioxidant for cells, prevents their change and rebirth, preventing the development of neoplasms. Also, the acid substance affects two important hormones - adrenaline and norepinephrine.

These hormones stimulate the human brain.

The total level of uric acid in men and women is a congenital indicator that is inherited. Her chemical structure similar to the formula of another stimulant - caffeine. people with congenital increased rate acids are most often active image life, are full of enthusiasm and have a penchant for creativity. But exceeding the permissible limit of uric acid content is a symptom of many diseases and pathologies.

How the study is done

A referral for a biochemical analysis is issued by a local therapist, nephrologist, endocrinologist or other doctor, based on the clinical picture. Blood is taken from a vein to determine the level of uric acid. Result, depending on the workload medical institution issued in a day or a few days later.

Blood sampling is usually carried out in morning time, after a night's rest and before breakfast. It is not recommended to eat and drink before the analysis, you can drink mineral water. Before the test, it is strictly forbidden to smoke at least for one to two hours. The use of alcohol, fried, spicy or smoked foods can distort the results of the test. The attending physician should be informed about the medications taken in advance, perhaps a few days before the analysis, the medication should be suspended.

Symptoms and clinical manifestations

The risk group for high blood uric acid is children and older men. AT childhood, especially in infancy, hyperuricemia manifests itself as skin rashes on cheeks and body. Pediatricians can diagnose such manifestations as diathesis, psoriasis, or simple allergic reaction. Eliminating suspected allergens from the diet of the breastfeeding mother and infant may solve the problem. However, it is necessary to monitor the level of uric acid.

In adult patients with a large amount of uric acid in the blood, the formation of salt crystals in the joints and tissues begins. With damage to the joints (usually the feet and hands), an inflammatory process begins and redness of the skin over the inflamed area. At the first symptoms, you should immediately go to the doctor. If the symptoms are ignored, the inflammatory process will intensify. Redness skin and inflammation increase, there are tangible pains in the joint.

Over time, the patient will lose the ability to move the affected areas.

Salts can affect genitourinary system to form kidney stones and bladder, as well as influence erectile function. Accumulations of urate cause inflammation, infection and sharp pain in inguinal region. Uric acid can accumulate in tissues and muscles. Nervous tissue damage can be recognized by general depression, impotence, constant fatigue and insomnia. Accumulation of urate in the heart muscle can lead to heart failure and heart attack. Sometimes the concentration of urates is manifested through tartar. In 20% of cases, hyperuremia does not cause obvious clinical symptoms.

Reasons for rejection

The amount of uric acid in a patient's blood sample is indicated on the test results form in numerical terms. Nearby, as a rule, the permissible limits of the norm are indicated. It is not difficult to understand which norm is for you, but it is important to use it correctly in diagnosis. The norm of uric acid in the blood in men is presented in the form of minimum and maximum limits. For different age groups In the blood, the norms of uric acid are:

Hyperuremia, or high levels of acid in the patient's blood, may be a symptom or cause of the disease. It often occurs in young children and manifests itself in the form of skin rashes. From adult category men over 50 years of age are most susceptible to hyperuremia (probability of 25%). If any symptoms of an increase in acid in the body appear, an urgent need to take a blood test, because timely treatment is the key to a quick recovery.

Non-Medical Causes of High Uric Acid

In addition to diseases, there are other reasons for the increase in the level of uric acid in the blood. Most often, the causes lie in malnutrition and the accumulation of purine substances in the body. Excessive consumption of meat, fish and eggs leads to the absorption of large amounts of protein. As a result, the product of protein breakdown is observed increased uric acid in the blood. This gives heavy load on the liver and kidneys, and also causes the accumulation of uric acid in the body. Normalization of nutrition will normalize the content of nitrogenous matter.

Starvation diets, including vegetarian ones, reduce the ability of the kidneys to excrete uric acid. Gradually, it accumulates and becomes the cause of inflammation, salt deposits and other diseases. Long term use alcohol also leads to high levels of nitrogenous substances. Heavy physical activity (more common male gender), which are of short duration. In women, pregnancy and pregnancy can cause an increase in acid, but this is not a violation.

Health food

Exceeding the norm of acid in a biochemical analysis is not a reason for panic. A timely visit to the doctor increases the chances of recovery. A high level of uric acid in the blood is normalized, first of all, with the help of nutrition. If a change in diet does not normalize the level of nitrogenous matter, the doctor will prescribe medication. At clinical nutrition it is recommended to completely eliminate or significantly reduce (on the recommendation of a doctor) the consumption of the following products:

• Meat, lard, fish, especially fatty parts fried
• Offal (liver, offal, kidneys, etc.)
• Ham, smoked meats, pickles, sausages and sausages
• Rich broths based on meat, fish or mushrooms
• Canned meat and fish
• Sour vegetables and herbs (tomatoes, sorrel, etc.)
• Sweets, sweets, chocolate
• Coffee Tea
• Any drinks and foods containing alcohol
• Carbonated drinks, juices and nectars of industrial production

Uric acid as a norm in men is present in the body in a certain amount. When deciphering the analysis, all external facts, the patient's lifestyle, genetic predisposition and clinical picture of the disease. Sometimes external signs(rashes, pain, etc.) may indicate a problem. With absence obvious symptoms appoint additional examinations and repeated blood tests. Perhaps the increase in uric acid in the blood was a one-time short-term phenomenon as a result of external factors.

In contact with

The norm of uric acid in the blood in men is an obligatory component in the composition of the plasma. It is formed in the liver from proteins nutrients, processed into small intestine. Like other components, it is very necessary in the body, but only in a certain amount.

Reducing or raising is fraught with health. Why is she needed? What is the benefit or harm? What to do if there is no norm? This will be discussed in the article.

Function

Uric acid - sodium salt is needed in the body for two reasons:

1. Strengthening the effect of adrenaline by acting on the brain.
2. It does not allow cells to degenerate into pathological ones, it performs the functions of an antioxidant.

Its quantity is controlled at the gene level. The action on the body is life-giving. Everyone who is elevated feels cheerful, active, creative. Excess exits through the kidneys, part with feces.

Hyperuricemia - excess of the upper limit of the norm. It can change within certain limits. Reasons for hesitation:

1. Large loads during training of athletes.
2. Those who want to lose weight with regular fasting.
3. Regular protein intake.

If the cause is eliminated, the analysis will return to normal. Continuous increase leads to severe deviations. Excess crystallizes and settles, causing various ailments.

Relationship with pathologies

• Gout is a disease caused by high content urea. Her crystals settle in the joints thumbs legs. The bone grows at the same time it becomes inflamed, there are severe pain, inability to move.

Acid is also deposited in other bones and joints. In some cases immobility.

• Urolithiasis, calculi develop a spasm in the urinary and kidneys, inflammation of the urinary system appears. Increased deposition of stones on the teeth, leading to periodontal disease, caries, loss.
• Myocardial infarction can occur when acid is deposited on the walls of blood vessels.
• Damage to the nervous system chronic fatigue, lethargy, indifference to everything, poor sleep.
• A negative effect on the tissues of the eyes leads to a deterioration in vision, ophthalmic diseases.

Reasons for the increase

1. The function of the kidneys, which must remove excess from the body, is impaired.
2. Enhanced liver function.
3. The use of a large number of products that are synthesized into acid.
4. Overweight.
5. Failure of the body to absorb vitamin B12.
6. chronic leukemia.
7. Long-term therapy with certain drugs.

downgrade

1. Congenital pathologies.
2. use of allopurinol.
3. Diabetes.
4. AIDS.

Treatment

Diet is the main method. It is necessary to exclude from the diet foods that are harmful to the liver. These are fatty, salty, smoked dishes. Carbonated water, juices, canned food, sausages, sweets. Do it once a week fasting days on kefir or cottage cheese.

If nutrition does not help, prescribe drug treatment. Sulfinpyrazone, Colchicine, Allopurinol - they should be drunk only as directed by a doctor, who will determine the dosage and duration of administration. Increase in drinking regimen.

It is necessary to drink more than three liters of fluid per day to remove uric acid from the body. ethnoscience offers teas from lingonberry, blueberry, mountaineer leaves.

Blood analysis

To determine the amount of acid, the following conditions must be met:

1. In the morning on an empty stomach.
2. For a few days, follow a diet, excluding fried, salty, smoked foods, do not drink alcohol.
3. Do not do ultrasound, x-ray, physiotherapy the day before.

The rate of uric acid in men is very important for the functioning of the body. An early diagnosis can help prevent heavy course illness. Visit our site. We are preparing new publications.

By-product of metabolism purine bases, which is in the blood plasma in the form of a sodium base, is uric acid or stone, the content of which in the blood, urine is one of diagnostic markers, symptom inflammatory processes, crystal deposits, disorders of purine metabolism. Both tall and low rate indicates pathological mechanisms in the body.

What is uric acid

The organic matter that is formed by-product the exchange of purines during metabolism is called uric (stone) acid. Its normal content does not harm the tissues of the body, but at an increased concentration in the blood, it begins to accumulate in cartilage and joints, causing their active inflammation. Salt crystals contribute to an increased risk of developing acute inflammation. An elevated level of a substance occurs when the urinary system does not function well (with kidney stones). An increase in uric acid in the blood is called hyperuricemia.

Formula

Organic matter, belongs to the class of dibasic acids, has the form of white crystals. When metabolized in the human body, it forms acidic and medium salts called urates. It exists in two forms - lactam and lictim. It was first discovered by the Swedish pharmacist-chemist Scheele in 1776, synthesized artificial method Gorbachevsky in 1882

Blood uric acid test

The measurement of this metabolite is not standard analysis, is prescribed by a doctor in case of suspected diseases that disrupt the metabolism or normal functioning of the kidneys. To study the acid content in plasma, blood is taken from a vein in the morning on an empty stomach, in an amount of 5-10 ml. Biochemical analysis in the laboratory is done for about a day using special sera, enzymes.

What does uric acid show in a blood test?

The content of the metabolite shows the state of all the main body systems, the type and quality of nutrition, the degree of functioning of metabolism. Elevated levels of uric acid means a malfunction of the kidneys, liver, or metabolism. Poor nutrition, an increase or decrease in the content of fructose in the diet immediately affects the amount of acid in the blood plasma. Excessive synthesis of a substance leads to deposition excess salts, violation normal exchange nucleic acids.

Deciphering a blood test

The number of metabolites of purine bases in the biochemical analysis of blood of the old sample is indicated by the abbreviation "ur. acids", in new electronic, clinical computer programs- the Latin abbreviation "UA". The content of a substance is expressed in kilomoles per liter of blood plasma, which refers to the number of molecules contained in the blood.

Norm

If the analysis shows that the content of the metabolite is on the border of the upper or lower norm, the attending physician must prescribe additional laboratory tests, instrumental research to collect the patient's medical history in more detail. The extreme indicator may indicate a developing pathological mechanism, early diagnosis which will avoid many symptoms and complications (kidney disease). Physiological norm uric acid in the blood is:

• in children under 14 years old - 120 - 320 µmol / l;
• in adult women - 150 - 350 µmol / l;
• in adult men - 210 - 420 µmol / l.

Uric acid in the blood is elevated

In therapy, two types of hyperuricemia are distinguished: primary and secondary. An idiopathic or primary disease is a disease that has arisen as a result of the inheritance of a mutated gene that is responsible for normal process breakdown of purines. Diagnosed in children in the first year of life, is rare. Secondary hyperuricemia occurs for a number of reasons: organ pathology (liver disease), malnutrition. Often occurs in the elderly, in conjunction with arthritis, patients with gout.

excess symptoms

With a slight increase in the level of the metabolite, the patient's well-being does not change. Significant damage to health is caused by constantly high or recurring hyperuricemia. Clinical picture, its intensity depends on the age of the patient:

1. Children up to 14-15 years of age have permanent signs skin problems: rash, peeling, itching, development of psoriasis. Affects physical development children under three years of age.
2. Men over 50-55 years old suffer from pain in the joints during movement and at rest, swelling of the limbs, gout attacks.
3. Middle-aged men and women suffer from severe itching, weeping rash on the body, pain.
4. In women, the microflora of the vagina suffers, attacks of exacerbation of candidiasis become more frequent. Hyperuricemia leads to prolonged menstrual irregularities.

The reasons

Hyperuricemia can be caused by two main causes of an increase in the concentration of urinary bases: a violation of their excretion by the kidneys and an increased breakdown of purines. In addition, some drugs may cause increased concentration metabolites in the exchange of purines, for example, diuretics. High content can be caused by the formation of their depot - the accumulation of crystalline salt.

Reasons for depositing can be:

1. Diseases of the urinary system. When the kidneys do not cope with the filtering function, metabolites settle, are deposited in the tissues of the joints, and gout develops.
2. Endocrine diseases. Diabetes mellitus, a tendency to acidosis cause intense breakdown of purines, and, as a result, high concentration end metabolites that cannot be excreted by the kidneys.
3. Improper nutrition, starvation, an excess of meat in food, dairy products.

Uric acid is low

A decrease in the concentration of a metabolite is diagnosed by a doctor when two or more biochemical analysis blood plasma showed the concentration of acid below the lower limit of the norm. The condition is due to a decrease in the production of a metabolite, an increase in excretion from the body along with urine, bile, acid breakdown under the influence of the uricase enzyme, which is a component of some drugs to combat gout.

The reasons

Among the reasons that cause a decrease in the number of purine metabolites, the following are distinguished:

• hereditary deficiency of xanthine oxidase - a disease in which xanthine is not converted to the final metabolite, due to the lack of enzymes;
• acquired xanthine oxidase deficiency;
• low purine or low protein diet;
• increased secretion substances in the urine;
• Fanconi's syndrome reverse suction acid in the tubules of the kidneys is maximally reduced;
• familial renal hypouricemia hereditary disease caused by a mutation of the genes responsible for the reverse absorption of purine metabolites;
• an increase in extracellular fluid volume.

Treatment

Therapy for the state of hypouricemia consists in diagnosing the disease that caused the decrease in the content of the metabolite. If the disease is hereditary, incurable, the doctor prescribes drugs that stop the symptoms of the disease. Mandatory basis of therapy is diet, lifestyle changes. The patient, to control the condition, is assigned an analysis every week, then every month.

How to lower the level of uric acid in the blood

To reduce the concentration of the metabolite is used drug therapy: diuretics, enzyme preparations, drugs that reduce the absorption of a substance renal tubules. For background treatment to reduce content by-products, nutritional adjustment is required - a decrease in the consumption of food containing a large amount of purines, their bases. A diet with elevated uric acid in women must necessarily include animal fats - this prevents an imbalance of sex hormones.

Medical therapy

The following medications are used to treat low or high acid levels:

1. Allopurinol. Medicine, produced in the form of tablets, 30 or 50 pcs. packaged. Hypouricemic, anti-gout agent. Prevents the synthesis of the enzyme xanthine oxidase, which enhances the production of purine bases to the final metabolites, metabolic products. From positive characteristics it is possible to allocate a cumulative effect, a soft gradual effect. The disadvantage of the drug is an aggressive effect on cardiovascular system.
2. Etamide. It is used to lower the concentration of acid by reducing its reabsorption by the renal tubules. It has a tablet form of release, is contraindicated in children under 14 years of age, patients with kidney failure helps to remove excess salts. A positive feature of the drug is the effect of reducing the synthesis of purines, reduces the content of sodium salts, negative - strong impact on the kidneys, which can lead to organ failure.
3. Sulfinpyrazone. Increases the excretion of acid by the kidneys with the help of increased diuresis. Release form - drops or tablets. Drops are prescribed mainly to children. The advantages of using the drug are a mild but strong effect. Cons - removes potassium and sodium from the body.
4. Benzbromanone. Prevents reabsorption of the metabolite back into bloodstream. Available in the form of capsules, tablets. Contraindicated for people with kidney disease. The advantages of using the drug are the cumulative effect of therapy, the disadvantages are that it contributes to the retention of salts and water in the interstitial fluid.

Diet

When a patient is diagnosed with changes normal level acids, he is prescribed special diet. Adjusting nutrition will not cure the disease, but will help bring the level of the metabolite into the normal range. The list of prohibited and permitted products depends on whether the content of the substance is increased or decreased. At high level forbidden to use protein food, fructose. If the content of the substance is lowered, then these foods, on the contrary, are mandatory for consumption.

Treatment with folk remedies

To reduce the level of acid, to increase its excretion by the kidneys, it is recommended to use infusions, decoctions of birch leaves, lingonberries, angelica root, bay leaf. Herbs contribute to the excretion of acid by the kidneys, reducing its content. Prepare a drink from the infusion as follows:

• two tablespoons of dry herbs should be added to a glass of boiling water;
• cover with a lid for 2-3 hours;
• use a tablespoon 2 times a day before meals.

Herbs, roots are considered potent means to remove salts. To combat inflammation of the joints, excretion urinary base, gout treatment can cook homemade ointment from burdock root. Burdock has an excellent anti-inflammatory effect, enhances excretion harmful substances, there is a decrease in uric acid in the blood, acidity of urine. If the acid is elevated, with regular use, patients note a decrease pain syndrome, decrease in swelling of the joint. So, to make an ointment from the burdock root should be as follows:

• take 4-5 units of ground burdock root, petroleum jelly, a tablespoon of alcohol;
• mix until the consistency of thick sour cream;
• apply to a sore joint;
• wrap in a towel or diaper;
• leave overnight.

How to increase uric acid

After detecting a low concentration of a substance, the doctor should prescribe additional research to identify a disease or condition that has caused a decrease in the amount of the end metabolite of purines. Prescribe medications, a special diet with a high protein content, vitamins, and reduce salt intake. In order to eliminate the decrease in the acid content in the blood, it is necessary to eliminate the cause of its occurrence. Helps reduce the risk of hypothermia correct mode use clean water.

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