How to cure vasculitis with folk remedies. Renal symptoms of hemorrhagic vasculitis. Therapy regimens for various degrees of severity of pathology

"Vasculitis" is a general term that combines a number of diseases characterized by inflammation of the vascular walls. With such pathologies, blood vessels narrow, and nutrition and oxygen supply to tissues deteriorates. The result is often tissue death and a sharp decrease in functional activity individual organs, up to their complete failure.

Treatment of vasculitis is carried out mainly by rheumatologists, but the variety of clinical manifestations often requires examination by doctors of other specializations.

Classification

According to the accepted classification, primary and secondary varieties of inflammatory lesions of the vascular walls are distinguished.

Depending on the type of vessels affected by the inflammatory process, vasculitis is divided into:

• arteritis (large vessels suffer - arteries);
• arteriolitis (affected arterioles);
• phlebitis (inflamed veins);
• capillaries (small blood vessels are affected).

The group of vasculitis includes the following diseases:

• hemorrhagic vasculitis (Schonlein-Genoch syndrome);
• Takayasu's disease (nonspecific aortoarteritis);
• microscopic polyangiitis;
• Kawasaki disease;
• mixed vasculitis;
• nodular polyarteritis;
• allergic vasculitis of the skin;
• Horton's disease (giant cell vasculitis);
• Wegener's granulomatosis;
• cryoglobulinemic vasculitis.

Why do vasculitis develop?

Primary vasculitis is considered by specialists as an independent nosological form. Exact reasons occurrence this disease remain unclear to date.

Secondary lesions of the vascular walls develop against the background of a wide variety of pathologies.

Possible causes of secondary vasculitis:

• infections (both acute and chronic);
• individual reaction of the body to the introduction of vaccines (sera);
• contact with chemicals or biological poisons;
• genetic factor (hereditary predisposition);
• thermal factor (overheating or organism);
• skin (including against the background);
• injuries of various genesis and localization.

Important:vasculitis often develops in people who have undergone.

Any of these factors, as well as a combination of two or more of them, can change antigenic structure the body's own tissues, this case- vascular walls. The immune system begins to perceive them as foreign, and activates the production of antibodies that further damage blood vessels. Thus, an autoimmune reaction is launched, in which inflammatory and degenerative processes develop in target tissues.

Symptoms of vasculitis

Clinical manifestations of pathologies of this group largely depend on the nature of the disease, i.e., the specific nosological form. Some vasculitis affect only the skin, causing only minor discomfort to the patient. Others cause multiple lesions internal organs leading to the death of a person.

A symptom common to all vasculitis is a more or less pronounced febrile reaction. An increase in body temperature is a typical reaction of the body to severe inflammation any localization. Hyperthermia may be intermittent; for inflammation of the vessels, daily temperature fluctuations are quite characteristic. At the peak of its increase, it often develops skin reaction in the form of rashes.

Other symptoms often observed in patients with vasculitis include:

• general weakness;
• severe physical and mental fatigue;
• pallor of the skin;
• myalgia (typical for the nodular form);
• paresthesia (sensitivity disorders);
• drop in visual acuity;
• periodic loss of consciousness ();
• deterioration or complete lack of appetite;
• sleep disorders;
• neuropsychiatric disorders;
• frequent inflammation of the oral mucosa;
• swelling in the temporal region (characteristic of Horton's disease);
• occurrence not associated with infection ulcerative lesions on the genitals (with Behçet's syndrome).

Typical clinical manifestations of vasculitis include hemorrhages of a small area with primary localization on the skin of various parts of the body. As the process progresses, they appear in muscle tissue, articular cavities and in areas of nerve endings.

Depending on which vessels are affected, a certain organ is predominantly affected. If the renal vessels are affected, kidney infarctions also develop more often. With the localization of inflammation in the coronary arteries, the risk of heart damage is high (up to the conditioned one). When the vessels that feed the articular tissues are affected, symptoms develop first of all, and other signs may appear only after a few weeks or even months.

Note:Arthritis caused by malnutrition and tissue oxygenation is characterized by the development of a pain syndrome that is not associated with increased physical exertion or injury. Against the background of vasculitis, inflammation usually develops in large joints.

A characteristic symptom of one of the most common vasculitis is hemorrhagic- is palpable purpura. These are skin rashes in the form of small hemorrhages with predominant localization on the folds of the limbs. Often revealed abdominal syndrome, which is characterized by intense pain in the abdomen.

When defeated coronary vessels cardialgia, shortness of breath and cardiac arrhythmias appear.

Wegener's granulomatosis is characterized by a predominant lesion of the nasal sinuses with the release of blood and pus from the nasal passages.

For any pathologies of this group, a protracted chronic course is typical with inevitable progression in the absence of treatment. They are also characterized by periodic exacerbations, during which the severity of clinical symptoms increases.

During laboratory diagnostics in the blood, a decrease in the level of hemoglobin (anemia) and a moderate increase in the number of leukocytes and platelets are often determined.

In the urine are determined shaped elements blood (leukocytes and erythrocytes), i.e. there is microhematuria; protein is often found.

Clinical symptoms are for the most part nonspecific, so a number of symptoms are required to make a diagnosis. laboratory tests(to confirm the inflammatory and autoimmune process), as well as hardware research methods -, computed tomography and. Conducted if necessary.

Treatment of vasculitis, prognosis and prevention

Therapeutic tactics is selected for each patient individually. When drawing up a treatment plan, the form of vasculitis, the severity of the process and the presence of concomitant pathologies are taken into account.

Main goals medical measures with vasculitis:

• achieving remission;
• relapse prevention;
• prevention of irreversible damage to organs and tissues;
• reducing the likelihood of complications;
• increasing the duration and improving the quality of life of the patient.

The basis of the treatment of vasculitis is pharmacotherapy. The patient is prescribed drugs that reduce the sensitivity of tissues and reduce the synthesis of antibodies. In particular, glucocorticoid hormones are shown. It is hormonal therapy that allows for a short time suppress abnormal activity immune system. If, with a complicated course of the disease, it is not possible to achieve positive results with the help of glucocorticoids, chemotherapy with the use of cytostatics is indicated.

If a hemorrhagic type of pathology is diagnosed, prerequisite successful treatment becomes rational.

A good therapeutic effect in most cases can be achieved by purifying the blood through plasmapheresis and hemosorption techniques.

With a mild course of the disease and in remission, drugs from the NSAID group () help. Patients, in particular, are prescribed Voltaren and Indomethacin, which allow, among other things, to reduce the intensity of the pain syndrome.

With vasculitis, drugs are shown that reduce the degree of permeability of the vascular walls and inhibit the process of thrombosis.

Note:treatment of vasculitis allergic genesis, in which only minor skin lesions are detected, possibly without the use of pharmacological preparations. In this case, the exclusion of the patient's contact with the alleged allergen comes to the fore.

Forecast

The prognosis largely depends on the location and severity of vascular inflammation, as well as on the number of affected organs.

Prevention

Hardening procedures are recommended to prevent vascular inflammation. One of the important preventive measures is to reduce the influence of adverse external factors on the body and normalize sleep and rest. Should not be taken pharmacological preparations without a doctor's prescription or getting vaccinated unnecessarily. All vaccines must be received according to National calendar vaccination.

Sovinskaya Elena, medical columnist

This is a group of diseases accompanied by inflammation and subsequent necrosis (necrosis) of the vascular wall. This group pathologies leads to a significant deterioration in blood circulation in the tissues surrounding the vessel. different forms of these ailments have both characteristic and general symptoms(fever, weight loss, rash that persists on pressure, joint pain). In the absence of treatment primary focus can spread and cause damage to other tissues or organs. Subsequently, the disease can lead to disability and even death.

While vasculitis is still insufficiently studied, and experts have not come to a consensus on the causes and mechanisms of inflammation, classification and tactics of therapy. Now this disease is classified as a systemic disease. connective tissue, and rheumatologists are engaged in its treatment. If necessary, infectious disease specialists and dermatologists can be involved in therapy.

According to statistics, both men and women are equally often ill with vasculitis, and most often they are detected in children and the elderly. Every year the number of such patients of a rheumatologist increases, and experts believe that such an increase in the incidence is associated with the uncontrolled intake of immune stimulants and environmental degradation.

Types of vasculitis

A disease such as vasculitis is classified according to different parameters.

According to the root cause, the following two forms of the disease are distinguished:

1. Primary - damage to the vascular wall is caused by unexplained reasons, presumably it is provoked by malfunctions in the immune system.
2. Secondary - damage to the vascular wall is a reaction to infections (tuberculosis, hepatitis, syphilis), systemic lesions(collagenoses, systemic lupus erythematosus, reactive arthritis), sarcoidosis, cancerous tumors, helminthic infestations or chemicals.

According to the severity of the course, vasculitis can be:

• mild degree - they appear only as a mild rash and do not cause a deterioration in the general condition;
• moderate degree - the patient has a profuse rash, joint pain, blood in the urine, and general state is moderate (loss of appetite, weakness);
• severe - the patient has a profuse rash, significant disorders in organs and joints, pulmonary and intestinal bleeding appear, kidney failure develops, and the general condition is severe.

Depending on the type of inflamed vessels, the following forms of vasculitis are distinguished:

• capillary - inflamed capillary walls;
• arteriolitis - the walls of arterioles are inflamed;
• arteritis - arterial walls are inflamed;
• phlebitis - inflamed venous walls.

Depending on the location of the affected vessels, the following forms and varieties of vasculitis are distinguished:

Giant cell temporal arteritis

Skin lesions - cutaneous leukocyte angiitis, periarteritis nodosa, cutaneous arteritis

Joint damage - hemorrhagic vasculitis

Heart involvement - isolated aortitis

General symptoms

Symptoms of vasculitis are extremely diverse, and the most characteristic sign of these ailments is a rash on the skin. The severity of the signs of the disease and the general condition of the patient largely depends on the form and type of vasculitis. In severe cases and if untreated, the disease can cause disability or death.

Signs of skin rashes with vasculitis can be varied, but a number of them allow you to distinguish this disease from others:

• the appearance of a rash is often associated with an infection;
• the rash appears against the background of an allergy, systemic, autoimmune or rheumatic disease;
• the rash is relatively symmetrical;
• the first elements of rashes appear precisely on the legs (usually in the area of ​​\u200b\u200bthe legs);
• elements of the rash are predisposed to hemorrhages, edema and necrosis;
• the rash is often represented by various elements that change their color, size and shape over time.

In patients with vasculitis, the following types of rashes can be detected:

1. Spots. They are red or pink elements of the rash that do not rise above the level of the skin. Caused by a rush of blood in response to inflammation.
2. Hemorrhagic purpura. Elements of rashes occur with significant damage to the vessel wall and hemorrhage. The rash may look like macules or purplish telangiectasias. The dimensions of elements with uneven contours can reach 3–10 mm. After a while, the rashes turn blue, and then acquire a yellowish tint. After pressing, the rash does not disappear.
3. Hives. Such a rash is provoked by an allergic reaction and is accompanied by burning, tingling and itching. It manifests itself in the form of pink or red bubbles with irregular contours.
4. Subcutaneous nodes. Such elements of the rash are caused by uncontrolled growth of connective tissue and epidermis. They are raised semicircular or flat nodules. Their size can vary from a few millimeters to 1–2 cm. They are painful, and over time, an area of ​​necrosis may appear in their center due to a significant violation of blood circulation. Subsequently, the skin in this place of the nodule turns black and begins to be rejected.
5. Bubbles. Violations of the permeability of the vascular walls in a certain area of ​​the bloodstream lead to the release of the liquid part of the blood under the skin. In such places, bubbles larger than 5 mm appear. They are filled with transparent contents, which may contain blood inclusions.
6. Ulcers and erosions. The subcutaneous nodes formed during vasculitis disintegrate over time, and erosions (superficial lesions) or deeper skin defects - ulcers occur in their place. When infected, they can suppurate.

Intoxication

Vasculitis is accompanied by circulatory disorders, leading to the formation of toxins, poisoning of the body and changes in metabolism. These processes cause the patient to experience the following symptoms:

• decreased exercise tolerance and weakness;
• loss of appetite and weight loss (up to 0.3-1 kg every month);
• frequent drowsiness;
• headaches (the degree of their intensity depends on the severity of the disease);
• temperature rise to 37.5-40 degrees (depending on the severity of the disease).

Nervous System Damage

Exposure to toxins and damage to the nervous tissue caused by circulatory disorders and hemorrhages in vasculitis provoke the following symptoms:

• sudden changes in the psycho-emotional state;
• seizures;
• muscle weakness, incomplete paralysis of the arms and legs,
• changes in sensitivity (more often by the type of "socks" and "gloves" - that is, in these areas of the body);
• hemorrhages in the brain, leading to the development of hemorrhagic stroke.

visual impairment

Observed in vasculitis insufficient blood supply and nutrition of the organs of vision can cause their one- or two-sided damage:

• constantly progressive deterioration of vision (up to complete blindness);
• swelling and redness of the eye;
• feeling of difficulty in moving the eyeball;
• protrusion of the eye.

Respiratory damage

The presence of an inflammatory reaction and a violation of the permeability of the vascular walls in vasculitis leads to edema and inflammation of different areas respiratory system. As a result, the following respiratory diseases can develop:

1. Prolonged runny nose.
2. Chronic sinusitis and sinusitis.
3. Destruction of the bony walls of the maxillary sinus or nasal septum.
4. Chronic bronchitis with asthmatic component.
5. Bronchial asthma.
6. Pleurisy.
7. Pneumonia.
8. bronchiectasis.

With ruptures of the walls of blood vessels, the patient develops broncho-pulmonary bleeding of varying intensity.

Kidney damage

Many types of vasculitis lead to malnutrition and kidney function. Initially, the patient shows signs of a decrease in their function, manifested by the following symptoms:

• lower back pain;
• fever;
• swelling;
• decrease in the volume of urine excreted;
• protein and blood in the urine.

Subsequently, circulatory and nutritional disorders in renal tissues becomes more pronounced, and the tissues of these organs are affected more massively. Because of such changes, the patient develops acute and then chronic renal failure.

Joint damage

Vasculitis is accompanied by damage to the joint bag, which is caused by the penetration of fluid into it, the development of inflammation and edema. The first to suffer most knee joints and the patient has the following symptoms:

• redness, swelling and rash in the knee area;
• intense pain leading to difficulty in motor function.

A few days later, the inflammatory process passes to neighboring joints and the pain in the knees becomes weaker. Typically, such joint damage resolves itself and does not lead to irreversible consequences.

Digestive disorders

Damage to the walls of the vessels of the mesentery and intestines causes a violation of blood circulation and leads to the appearance of hemorrhages. As a result, an inflammatory reaction develops and a patient with vasculitis develops the following symptoms:

• paroxysmal and intense pain in the abdomen, aggravated half an hour after eating;
• nausea and vomiting;
• quickened stool watery character(sometimes with inclusions of blood).

Massive vascular damage can cause atrophy, gradual destruction and rupture of the intestinal wall. With such large-scale lesions, the patient develops peritonitis.

Treatment

Treatment of vasculitis should be complex, and its tactics depend on the severity and type of disease. It can be done on an outpatient basis or in a rheumatology department.

Indications for hospitalization of a patient with vasculitis are as follows:

1. Moderate or severe form.
2. Debut or exacerbation of the disease.
3. Pregnancy period.
4. Childhood.
5. hemorrhagic vasculitis.

During the acute phase of the rash, patients are advised to stay in bed, which contributes to the disappearance of the rash and stabilization of blood circulation. A week after the appearance of the last elements of the rashes, the regimen is gradually expanded.

Medical therapy

The choice of certain drugs for the treatment of vasculitis can only be performed by a doctor, taking into account the patient's examination data, the severity and type of the disease. At mild form taking drugs is prescribed for 2-3 months, with moderate - for about 6 months, and with severe - up to a year. If vasculitis is recurrent, then the patient is treated in courses of 4-6 months.

The following drugs can be used to treat vasculitis:

• non-steroidal anti-inflammatory (Ortofen, Piroxicam, etc.) - eliminate inflammatory reactions, joint pain, swelling and rash;
• antiplatelet agents (Aspirin, Curantil, etc.) - thin the blood and prevent the formation of blood clots;
• anticoagulants (Heparin, etc.) - slow down blood clotting and prevent thrombosis;
• enterosorbents (Nutriklinz, Thioverol, etc.) - bind toxins and bioactive substances formed during the illness in the intestinal lumen;
• glucocorticosteroids (Prednisolone, etc.) - have an anti-inflammatory effect in severe course vasculitis, suppress the production of antibodies;
• cytostatics (Azathioprine, Cyclophosphamide, etc.) - are prescribed for the ineffectiveness of glucocorticosteroids and the rapid progression of vasculitis, suppress the production of antibodies;
• antihistamines (Suprastin, Tavegil, etc.) - are prescribed only for children initial stages vasculitis in the presence of drug or food allergies.

Non-drug therapy

With vasculitis, to cleanse the blood of substances that cause and aggravate the disease, the attending physician may recommend that the patient undergo various techniques gravitational blood surgery:

1. Immunosorption - venous blood is purified by passing through an apparatus with an immunosorbent.
2. Hemosorption - blood is passed through a device with a sorbent that purifies it from antibodies, immune complexes and antigens.
3. Plasmapheresis - blood passes through a special apparatus that purifies or replaces its plasma.

Hypoallergenic diet and nutrition

Vasculitis often predisposes to an allergic reaction, and to prevent such a complication, patients are advised to exclude the following foods from their diet:

• eggs;
• chocolate;
• red fruits and berries (especially strawberries and strawberries);
• citrus;
• honey, royal jelly, pollen;
• products with flavor enhancers, stabilizers, dyes and non-natural flavors (sausages, flavored cheeses, pates, crackers, chips, etc.);
• mushrooms;
• pastries from sweet dough;
• canned food;
• coffee and strong tea;
• spicy, salty and fried foods;
• alcohol;

Phytotherapy, non-traditional and folk methods

Self-treatment of vasculitis is unacceptable, because taking certain medicinal herbs can provoke allergies and aggravate the course of the disease. In the absence of contraindications, a rheumatologist may recommend the following herbal remedies, non-traditional and folk methods:

• liquorice root;
• herbal teas based on calendula, horsetail, poplar buds, string, elder flowers, peppermint, yarrow, etc.;
• hirudotherapy (medical leeches).

Forecasts

The prognosis of this disease depends on its type and form, the age of the patient, the presence of complications and the timeliness of the start of therapy. Five-year survival patients with severe vasculitis, the treatment of which was started immediately and with the use of glucocorticosteroids and cytostatics, is 90%. Without timely therapy, this figure is only 5% and leads to disability and death.

The following clinical cases can worsen the prognosis for vasculitis:

1. Kidney damage.
2. CNS damage.
3. Damage to the coronary vessels and aorta.
4. Damage to the digestive organs.
5. The development of vasculitis after 50 years.

These facts mean that people with such diseases need constant dispensary observation and strict adherence to all doctor's recommendations. This attitude to their health will help them avoid the development of serious complications.

Vasculitis - what is this disease and how to treat it. Forms of vasculitis, symptoms and manifestations in children and adults

Every year, the problem of autoimmune diseases becomes more and more urgent. This is the name of pathologies in which a person’s immunity attacks cells that are not dangerous for the body, but their own. Among the many autoimmune diseases, vasculitis is common. The severity of the disease lies in inflammation and damage to the walls of blood vessels.

What is vasculitis

Vasculitis (ICD code 10) is pathological condition an organism in which the walls of blood vessels of various sizes become inflamed: capillaries, venules, arteries, veins, arterioles. They can be located in the dermis, on the border with the hypodermis, or in any other body cavity. The disease vasculitis is not one disease, it is a group of pathologies that are united on a single basis. Doctors distinguish several types of the disease, differing in the place of localization, the severity of the process, and the etiology:

1. Primary. It starts as an independent disease with its own symptoms.
2. Secondary. It develops in the presence of other pathologies (tumors, invasion). May occur as a reaction to an infection.
3. System. The disease progresses in different ways. It is characterized by damage to the vessels with inflammation of the vascular wall, may be accompanied by necrosis.

Vasculitis - causes

Modern medicine has not yet fully understood all the causes of vasculitis. Now there are several opinions regarding the origin of this disease. According to one theory, pathology develops against the background of a viral or infectious disease. Especially often the vessels become inflamed after hepatitis, when an abnormal reaction of the immune system to the pathogen occurs.

The second version is the autoimmune nature of the disease. Doctors believe that the pathology is provoked by the human immune system itself, when it does not recognize its cells and reacts to them as to a foreign element. The third theory is related to the genetic nature. According to this version, hereditary predisposition, combined with unfavorable external factors increase the chances of getting sick.

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Vasculitis - symptoms

Depending on the type of pathology, its symptoms also differ. Primary vasculitis is accompanied by symptoms that are characteristic of most diseases: muscle and headache, a slight increase in temperature. In the future, signs of damage to the organ, the vessels of which begin to undergo a pathological process, appear. The main symptoms of vasculitis:

Vasculitis - classification

All forms of vascular inflammation are inherently the same, but there are some differences. Some pathologies lead to irreversible consequences and death, while others only affect the skin. Classification of vasculitis according to the degree of vascular damage:

1. Large:

• tropical aortitis;
• Cogan's syndrome;
• sarcoidosis;
• giant cell arteritis;
• Takayasu's disease (nonspecific aortoarteritis).

1. Medium:

• familial Mediterranean fever;
• lepromatous arteritis;
• striatal vasculopathy;
• nodular polyarteritis;
• Kawasaki disease.

1. Small (cryoglobulinemic form):

• urticarial vasculitis;
• Dego's disease;
• Pigmentary purpura of Schemberg;
• cutaneous leukocytoclastic angiitis;
• thromboangiitis obliterans;
• Churg-Strauss syndrome (eosinophilic granulomatosis);
• Wegener's granulomatosis;
• Behcet's disease;
• Henoch-Schonlein disease.

Depending on the size of the blood vessels, inflammation of the vessels is divided into several groups:

• phlebitis (inflammation is concentrated in the venous wall);
• capillaritis (capillaries are involved);
• arteriolitis (arterioles are damaged);
• arteritis (the walls of the arteries are involved in the pathological process).

Vasculitis on the legs

The inflammatory process of the veins of the lower extremities proceeds ambiguously, since several tissues and organs are involved in the pathological process. What is vasculitis of the vessels in the legs? This is an autoimmune disease of the walls of the veins, which outwardly does not look very aesthetically pleasing. Vasculitis on the legs has subcutaneous hemorrhages, is characterized by inflammation and subsequent destruction of the vascular walls. Processes eventually lead to tissue death. This pathology often occurs in women and adolescent girls. The disease is manifested by such symptoms:

• rash or pruritus on the affected area;
• joint/muscle pain;
• blood bubbles;
• hemorrhagic spots.

Systemic vasculitis

This is a whole group of diseases leading to ischemia of tissues or organs. Any systemic vasculitis is aggravated by damage to the organs of vision, joints, lungs, heart, kidneys, and skin. The diagnosis is confirmed by visceral angiography, biopsy, laboratory tests. Often systemic pathologies sick middle-aged men. The symptoms of this group of diseases are different and depend on the current form.

neurovasculitis

The disease can develop under the influence of cold or on nervous grounds. Neurovasculitis is characterized by ischemia of the extremities and spasms of cerebral vessels. Pathology belongs to the category of chronic, therefore, at the first symptoms, you should definitely contact vascular surgeon. Signs of primary neurovasculitis:

• clouding and confusion of consciousness;
• disorientation;
• chronic encephalopathy;
• headache;
• neuropathy of cranial nerves;
• stroke.

perivasculitis

When arterial wall is completely destroyed, it ruptures and subsequently hemorrhages into neighboring tissues. Perivasculitis is a lesion and inflammation of the outer layer of the vessel and connective tissue, which often leads to necrosis, gangrene. The disease may be located in different places. More common is polyarteritis nodosa, which affects the arteries of small and medium sizes: the brain, liver, renal, coronary and mesenteric vessels.

autoimmune vasculitis

There are many causes and forms of autoimmune vasculitis. Symptoms directly depend on the type of disease. The main symptoms include damage to the skin (sensitivity, rash), syndrome chronic fatigue, insomnia. Exacerbation alternates with remissions. The hematological form is characterized by chest pain, cough with shortness of breath and copious sputum. Takayasu's arteritis is characterized by weight loss, damage to the carotid and renal arteries, often ending in a heart attack. With Behçet's disease, stomatitis develops, the eyes become inflamed, ulcers appear on the genitals.

Hemorrhagic vasculitis

It belongs to the most common form of the disease. Hemorrhagic vasculitis - what is this disease? Pathology is also called capillary toxicosis, allergic purpura, Shenlein-Genoch disease. Hemorrhagic vasculitis is an aseptic systemic inflammation of blood vessels with damage to the joints, skin, renal glomeruli, and gastrointestinal tract. A child from 7 to 12 years old is more susceptible to the disease. Adults rarely suffer from this form of pathology. The main cause of allergic purpura are infections: influenza, herpes, SARS, streptococci, mycoplasma and others.

allergic vasculitis

Pathology occurs as a manifestation of allergies. Different circumstances suggest the development of allergic vasculitis: infections, regular medication, work with chemical industry products. Vascular walls become inflamed due to the reaction of the immune system to the effects of toxic-infectious factors. Diagnostics allergic form diseases are A complex approach instrumental (plasmapheresis) and laboratory examination taking into account the clinical picture and anamnesis.

rheumatic vasculitis

This form of pathology often develops in men. The classic signs of rheumatic vasculitis are: lung damage, pericarditis, scleritis, mononeuritis, peripheral gangrene. Rheumatoid vasculitis is divided into three clinical and histological types:

1. necrotizing arteritis. Medium and small arteries are involved, leading to lesions peripheral nerves and visceral organs.
2. Inflammation of capillaries, arterioles, arteries, venules. Skin ulcers and palpable purpura are characteristic.
3. motor arteritis. In patients with this type of pathology, vascular intima proliferation, thrombosis, and damage to the nail phalanges are observed.

Necrotizing vasculitis

This form of pathology refers to skin necrosis, which develops in large areas. Necrotizing vasculitis is not one disease, but a whole group of diseases with a similar mechanism of action. Although the disease is not easy, the prognosis with timely treatment is conditionally favorable, since it allows to lengthen the remission and reduce the relapse rate. The main symptoms of necrotizing vasculitis are:

• tingling, numbness, pain in different parts body;
• muscle contractions;
• non-healing wounds (ulcers);
• speech disorders;
• difficulty swallowing;
• blue toes, hands;
• skin redness;
• blood in stool and urine.

Vasculitis treatment

The most effective therapy This pathology is observed when diagnosing it at an early stage. Treatment of vasculitis is carried out in a hospital or at home, depending on the severity of the disease. Drug therapy with a mild form of the disease lasts 2-3 months, with an average one - six months, with a severe one - up to a year. Chronic pathology is treated in courses of 4 to 6 months with the same break. Helps in curing the disease plasmapheresis, hemosorption, herbal medicine, diet. With drug treatment, patients are prescribed:

• anticoagulants and antiplatelet agents: Warfarin, Heparin;
• vasodilators: Dipyridamole, Tetamon;
• glucocorticoids: Cortisone, Triamcinolone;
• ACE inhibitors: Captopril, Perindopril;
• anti-inflammatory nonsteroidal drugs: Ketoprofen, Acetaminophen.
• cytostatics: Leflunomide, Methotrexate.

How is vasculitis treated? What medicines? Will we heal?

The involvement of doctors of different specialties is the main condition that the disease requires vasculitis. Treatment, as well as diagnosis, is complicated by the variety of symptoms. Patients at the initial stage of pathogenesis feel a general weakness of the body, periodic increase body temperature, morning stiffness in the joints of the extremities. On the part of the skin, a rash appears, resembling hives. Based on the characteristic signs, patients often do not understand who treats vasculitis and which specialist to contact in the first place. A visit to a medical institution begins with a therapist. Then specialized neuropathologists, a cardiologist, a rheumatologist, a dermatologist, an otolaryngologist and an oculist are involved in the examination of the patient.

It is worth clarifying that a distinction is made between primary and secondary vasculitis disease. Treatment of the primary form of pathology is more difficult, since its etiology has not been fully elucidated. Presumably, damage to blood vessels and organs is associated with autoimmune processes. The secondary form of the disease leads to inflammation and subsequent necrosis of blood vessels due to infectious lesions, which can also be caused by an allergic reaction to medication.

It is known that with any type of pathology, simultaneous damage to large, medium and small vessels is possible. How to cure vasculitis and differentiate the disease according to clinical manifestations in this case? To correctly diagnose and prescribe adequate therapeutic measures, doctors act according to the following scheme:

• according to the clinical picture, the variant of the presence of vasculitis is suggested;
• the method of examination excludes the possibility of similar pathologies;
• assess the stage of destruction of the vessel wall and the prevalence of the lesion;
• with the help of instrumental and laboratory tests confirm the diagnosis.

The sooner the patient enters the walls of the hospital, the easier it is to stop vasculitis. Is it possible to cure the advanced stage of pathology? Yes, but the long-term development of the disease provides damage to the veins, arteries and internal organs, so the therapy will be long.

How is Vasculitis treated?

Varicose veins - a terrible "plague of the XXI century." 57% of patients die within 10 years of.

Since fever (usually of unknown etiology) and lesion different systems organism - these are the signs that characterize the disease vasculitis, treatment is based on the principle:

• Determination and elimination of an exogenous factor, that is, the drug is canceled, disturbing homeostasis;
• Carrying out therapy of the main cause that caused the appearance of vascular and organ pathology, for example, with antibiotics or anti-inflammatory cytokines.

Depending on the severity of the course of the disease, the appointment of therapy with the use of drugs to suppress the immune system. If this is an autoimmune vasculitis, the treatment will be less intense, provided the localization of the foci of inflammation is limited (photo). And the pathological activation of antibodies, which led to damage to large and medium-sized arteries, should be subjected to a system of therapeutic measures to correct impaired vital functions and organs.

Approximately 15% of patients report sudden manifestation blurred vision, which in a few weeks can turn into blindness as a result of damage to the vessels of the retina. In addition, hemorrhagic vasculitis affects the kidneys, gastrointestinal tract and vessels of the heart, and then death is not excluded. Therefore, the question of whether vasculitis is curable can only be answered positively if the disease is diagnosed in time and adequate therapeutic measures are taken.

Medicines for vasculitis

Patients need intensive long-term therapy. To cure vasculitis, the medicine must restore the work vascular system and stop the abnormal immune response. In some cases, chemotherapy is prescribed in small doses. Rheumatologists prescribe anti-inflammatory drugs, corticosteroids. AT complex treatment there are blood purification procedures and mandatory bed rest.

1. The drug Heparin is administered subcutaneously under the control of blood clotting, since it is a strong direct-acting anticoagulant.
2. Curantil - the drug is indicated for the prevention and treatment of circulatory disorders.
3. The antiallergic agent Suprastin provides desensitization of the body.
4. Tavegil - this medicine has an antihistamine effect and strengthens the walls of blood vessels.
5. In severe cases of joint damage, Prednisolone is prescribed up to 15 mg per day.
6. For cupping clinical signs vasculitis take immunomodulators and vitamins.

Ointments for vasculitis for local therapy

External influence on the vessels plays important role in treatment. Vasculitis ointment provides skin elasticity and strength, restores vein tone and blood circulation hemodynamics. Experts prefer:

1. Acemin ointment - cleanses inflammatory foci from necrotic masses, stops the release of exudate, activates epithelialization and strengthens bone tissue;
2. Methyluracil 10% is a topical drug that promotes tissue regeneration and relieves inflammation;
3. Iruksol ointment - the composition contains the antibiotic chloramphenicol, the drug cleanses of necrotic tissues, kills microbes;
4. Troxevasin is an angioprotector, reduces the fragility of blood vessels and has an anti-inflammatory effect.

pathogenetic complex therapy with vasculitis is directed to full recovery the work of internal organs and systems, and the prevention of irreversible complications.

Ksenia Strizhenko: “How did I get rid of varicose veins in my legs in 1 week? it inexpensive remedy works wonders, it's common. "

Vasculitis - methods of treatment, diet for vasculitis, traditional medicine, consequences, prognosis and prevention of the disease. Vasculitis in children: causes, symptoms and diagnosis, treatment and prevention

Vasculitis treatment

• childhood;
• vasculitis during pregnancy;
• hemorrhagic vasculitis;
• start and exacerbation of vasculitis.

In the acute phase, for the period of rashes, patients need bed rest. It improves blood circulation and promotes the disappearance of the rash. 7 days after the last rash appears, you can switch to a less strict regimen.

Medical treatment

Non-drug therapy

Vasculitis of large vessels - temporal arteritis: description, diagnosis, treatment of the disease - video

Granulomatous vasculitis (Wegener's disease, granulomatosis with polyangiitis): what is this disease, signs and symptoms, treatment methods - video

Nutrition for vasculitis

• citrus fruits - oranges, tangerines, lemons;
• strawberries, wild strawberries;
• red apples;

Vasculitis in children

The reasons

• frequent acute infectious diseases (viral and bacterial);
• infection with helminths (worms);
• vaccination - individual intolerance to the components of the vaccine.

According to statistics, vasculitis often occurs in children who have experienced allergic reactions - atopic dermatitis, food allergy, allergy to plant pollen, medicines and household chemicals.

Symptoms

• An increase in temperature to 37.5-39 degrees.
• Weakness, lethargy.
• slimming or weak set weight.
• Rash on the skin. Mostly it is located on the lower extremities and torso. It looks like small subcutaneous hemorrhages that do not disappear with pressure. At the same time, other elements of the rash can be detected on the skin: nodules, blisters, vesicles filled with a clear or reddish liquid.
• Pain in large joints. Vasculitis is characterized by:

• symmetrical joint damage;
• redness and swelling of the affected joints;
• hemorrhagic rashes ( small hemorrhages) on the joints.

Forecast

• the onset of the disease after 50 years;
• kidney damage;
• damage to the gastrointestinal tract;
• damage to the central nervous system;
• damage to the aorta and heart vessels.

This means that people with these conditions need to be attentive to their health and strictly adhere to the treatment regimen. In this case, it is possible to avoid the development of serious complications.

Prevention of vasculitis

• Sanitation of foci of infection - treatment of carious teeth, chronic tonsillitis, adnexitis;
• Limiting sun exposure;
• Exclusion of contact with allergens;
• Exclusion of stress and hypothermia;
• Dosed physical activity;
• Rational use of medicines;
• Healthy food based on organic products.

Vasculitis is an inflammatory process in the walls of blood vessels of an infectious-allergic or autoimmune (with an allergy to the patient's own tissues) nature. Such processes take a long time, and if they are not treated correctly in time, sooner or later they lead to severe disorders on the part of various organs and tissues.

The consequences of vasculitis - what they depend on

Different types of vasculitis occur in different ways and their consequences can be different. In addition, the consequences of vasculitis depend on many other things: on the age and individual characteristics of the patient's body, the presence of other chronic diseases, forms of the disease and so on.

But the greatest influence on the consequences of vasculitis has the timeliness of its detection and immediately prescribed adequate treatment. Today there are modern techniques treatment of such patients, which allow to suppress the inflammatory process and constantly maintain a state of remission.

But if available general schemes therapy, all doctors agree that the approach to treating each patient with vasculitis should be individualized. It is very important to install on time correct diagnosis also because primary or systemic vasculitis and secondary (developing against the background of some other disease) are treated differently.

Meta

Hemorrhagic vasculitis consequences and limitations

Treatment of vasculitis is prescribed depending on its type and causes. The basis of such therapy is immunosuppressants, anti-inflammatory drugs and medications designed to improve blood flow in the blood vessels. At the beginning of treatment, especially in children, consultations of specialized doctors are necessary, and with the development of complications, neuropathologists, therapists, surgeons, otolaryngologists, oculists should be “connected” to the treatment, since a unified approach is important in the treatment of this disease.

Diagnostic measures

Vasculitis is detected after a doctor's diagnosis and a biopsy procedure

Unfortunately, the diagnosis of vasculitis cannot be made with specific laboratory tests. The main indicators in the study of vasculitis reflect the activity of the disease, which is expressed in an increase in ostrophase ESR, blood proteins, leukocytes, and you can also notice the degree vascular lesion in individual organs. During the examination, the doctor attaches great importance to a biopsy taken from the area where the changes in vasculitis were most pronounced. For common forms of vasculitis in clinical diagnostics a number of characteristic features are indicated, for example, with Wegener's granulomatosis, normochromic anemia with moderate leukocytosis without eosinophilia, thrombocytosis, high rate ESR and hypergammaglobulinemia.

With vasculitis, immunoglobulins (IgA) may increase, acute phase proteins will correspond to the activity of the disease, and rheumatoid factor is found in 50% of patients and is often determined in the advanced stage with severe disease activity. In general, each of the subtypes of vasculitis has its own characteristic criteria, thanks to which the doctor can say with a 100% guarantee about the absence or presence of the disease.

The first stage of diagnosis for vasculitis requires a thorough examination of the patient and the study of the affected organs. Some experts note that treatment for the allergic form of vasculitis is not required, it goes away on its own. But if internal organs (kidneys, lungs, brain) are involved in the pathological process, then treatment is started immediately.

It is worth noting that when diagnosing vasculitis, the examination does not establish its cause, then the collection of anamnesis comes to the rescue. For example, vasculitis may appear after a viral illness, or certain drugs and allergic reactions to food can trigger a surge in vasculitis. When collecting an anamnesis, note:

1. increase in body temperature;
2. weight loss;
3. fatigue and headache.

The disease is characterized by a constant (subfebrile) temperature, which does not decrease even with the appointment of antibiotics. But when taking glucocorticoids, the temperature may decrease. The classic sign is weight loss short period time, this circumstance is important diagnostic value with vasculitis and is evidence active phase diseases.

Some groups of patients have a clear predisposition to one form of the disease. Thus, Burger's thromboangiitis obliterans affects mainly men, nonspecific aortoarteritis is characteristic of young girls, changes in the temporal artery are usually found in people over 55 years of age, and hemorrhagic vasculitis occurs mainly in children or young people.

Principles of disease therapy

How to treat vasculitis? This question is often heard by specialists from patients who come to the appointment. To begin with, it should be remembered that all types of vasculitis are chronically occurring progressive diseases. Periods of remissions, followed by periods of exacerbation, can only be treated purposefully.

Currently, immunosuppression (immune suppression) and anti-inflammatory therapy are distinguished as the central direction in the treatment of vasculitis. It is the use of glucocorticoids and/or cytostatics that can limit (or interrupt) the development of immune inflammation.

The most advanced treatment for vasculitis is prednisolone.

Until now, prednisone remains the drug of choice. It quickly removes edema from the vascular wall, which leads to a decrease in the symptoms of ischemic syndrome. Besides long term appointment glucocorticoids in vasculitis in maintenance doses gives a favorable prognosis for the disease and prevents further stenosis of large vessels. Because systemic vasculitis is autoimmune disease, then it can be cured by maximally reducing the immune response of the patient's own body, this is what reduces the intensity of the manifestation of vasculitis. It should be remembered that taking drugs can last a lifetime so that the patient has a long and stable remission.

It has been proven that taking cytostatics, in particular cyclophosphamide, gives a significant improvement in the prognosis of the disease. The dose of the drug for vasculitis can vary widely, the first doses during the period of pronounced clinical symptoms are 2-3 mg / kg per day. To intensify the treatment of vasculitis, especially in severe torpid course, a combination of methylprednisolone and cyclophosphamide in high (1000 mg) IV doses is prescribed.

Concomitant therapy, namely the use of vasodilators (persantin, complamin, nicotinic acid) and antithrombotics (agapurine, chimes, trental), gives a good effect in treatment, but drugs should be prescribed for long courses. The method of extracorporeal hemocorrection is used to improve microcirculatory disorders (plasmapheresis is used in combination with hemooxygenation and ultraviolet blood irradiation). To correct microcirculatory disorders, prescribe: anticoagulants (heparin), methylxanthines (trental), NSAIDs (small doses of aspirin).

With an allergic form

Therapy of allergic vasculitis involves determining the degree of disease activity and, if possible, immunosuppressive treatment should be avoided, as the patient's resistance to other diseases decreases. In addition, it is necessary to take into account the toxic and side effects drugs, and switch to an alternating regimen when prescribing glucocorticoids.

Generally drug treatment vasculitis with allergic manifestation helps a little. Fortunately, with this form of vasculitis, the skin is damaged and, if an antigen is established, then it is eliminated, and with the infectious nature of vasculitis, antimicrobial therapy is carried out.

Secondary allergic vasculitis is curable, and often resolves on its own with successful treatment of the underlying disease. In this case, limited symptomatic treatment. Against the background of rheumatic diseases, with damage to internal organs, the use of glucocorticoids (prednisolone) is indicated, but it is best to cancel it as soon as possible, in some cases it is taken every other day.

In cases of long-term isolated skin lesions, the effectiveness of treatment decreases.

With a long-term isolated skin lesion, one should not expect a quick improvement from any drug, which is why immunosuppressants are “addressed” last and only when high risk occurrence of irreversible damage to internal organs.

The fulminant course of allergic vasculitis requires the use of plasmapheresis, in which case the patient is transfused with donor plasma, otherwise the consequences can be very unpleasant. More modern technologies suggest using the method of extracorporeal hemocorrection, which purposefully changes the activity of the immune system and selectively removes immune complexes.

Features of external therapy

When eliminating skin vasculitis, the following drugs are used, sequentially:

1. NSAIDs (reopyrin, naproxen, diclofenac, indomethacin);
2. preparations of Ca and salicylates;
3. antioxidant complex and vit. C, R;
4. at erythema nodosum use a 2% solution of potassium iodide, 1 tbsp. l. 3 times a day;
5. vasodilators (xanthinol nicotinate, pentoxifylline);
6. antiplatelet agents and anticoagulants;
7. methods of detoxification in/in drip;
8. glucocorticosteroids (GCS) 30-35 mg/day for 8-10 days and cytostatics;
9. ultra-high frequency therapy, ultraviolet irradiation, inductothermy, diathermy, ultrasound with hydrocortisone.

With erosive and ulcerative rashes:

• epithelial ointments (solcoseryl);
• 1–2% solutions of aniline dyes;
• ointments containing glucocorticoids, etc.;
• Dimexide applications;
• lotions or ointments with proteolytic enzymes (Iruksol, Himopsin).

Inflammation of small veins

Getting rid of urticarial vasculitis begins with a complete examination of the patient, it can manifest itself wherever there are small veins in the skin, the formation of dense blisters on the skin of the lower extremities is characteristic. Therapy is based on the suppression of the inflammatory process in the walls of the veins, therefore, antihistamines and NSAIDs are prescribed. With the ineffectiveness of this treatment resort to the help of glucocorticoid drugs.

The appointment of plasmapheresis in cases of primary detection of vasculitis leads to a faster recovery

Shown phototherapy, plasmophoresis - it is prescribed to cleanse the blood of immune complexes in vasculitis, which destroy the walls of blood vessels. In the primary form of urticarial vasculitis, treatment is fast and high-quality, but with secondary form vasculitis - you should pay attention to the underlying disease, which caused urticarial vasculitis.

Assistance with drug fees

Treatment of vasculitis with folk remedies is an addition to the main treatment. The following popular fees are used for therapy:

• Elderberry flowers, Sophora japonica fruit, knotweed and yarrow herb, nettle leaves

Everything is carefully crushed and mixed in one bowl for 4 tbsp. l. each ingredient. Then 1 tbsp. l. medicinal mixture is added to a glass of boiling water, infused for 1 hour, filtered. Drink with vasculitis in 2-3 doses of half a glass.

• Poplar buds, yarrow herb, marigold and elderberry flowers, string leaves, horsetail and mint

The collection remarkably relieves allergic reactions even in severe forms of vasculitis. The ingredients should be mixed in 3 tablespoons, take a tablespoon of the collection and pour a glass of boiling water, leave for an hour, strain and take half a glass every three hours.

• Bitter herbs and badan thick-leaved

Dry leaves of badan thick-leaved are added to boiling water (200 ml) and infused in a thermos all night. In the morning, filter, add 1 tbsp. honey and drink on an empty stomach. This infusion is good to use for blood purification.

It is good to cleanse the intestines with bitter herbs, suitable for this: elecampane, tansy, immortelle and wormwood. The grass is dried, take 2 tbsp. and pour boiling water (1 liter). At least 2 hours insist in a thermos, strain and drink warm 30 minutes before meals twice a day, diluting 1:1 with warm water.

• Pine rosin and nettle

Some types of vasculitis (Behçet's syndrome) are characterized by ulcers on the genitals. For the treatment of such an infection, folk methods use silver water and Velcro.

Velcro is prepared in several stages. Pine rosin (200 g) is dissolved in a water bath, beeswax (40 g) is added to the container, melted and combined with unrefined sunflower oil(40–50 g), stir until smooth. A small piece of linen cloth, smear with a solution and attach to the lower abdomen. The compress is kept on the body for up to 3 days, removed by soaking with warm water, and a new Velcro is applied. Procedures are carried out until recovery.

The hemorrhagic form of vasculitis is treated with young nettle juice (burning). Juice drink 2 tbsp. no more than 4 days.

• Violet infusion

Allergies in vasculitis are treated with a decoction of tricolor violet, lingonberry and string. Each plant is taken in 3 tbsp. mix and take 2 tbsp. mixtures. Pour 2 tbsp. boiling water and insist in a dark place for at least an hour. Take 1 cup 4 times a day, children - 2 times a day.

How to eat when sick?

Proper nutrition with vasculitis helps to reduce the progression of the disease

The diet for vasculitis requires compliance with certain restrictions, each form of pathology has its own characteristics in nutrition. Hemorrhagic vasculitis requires hypoallergenic nutrition and the rejection of food components that provoke individual allergic reaction. General recommendations are to avoid alcohol, it provokes an exacerbation.

Taking glucocorticoids increases blood pressure, so the patient is advised to limit the intake of salt and salty foods. Some medications can increase lipid and blood sugar levels, making it important to monitor your calorie intake. From unhealthy products - carbohydrates, refractory animal fats, it is better to refuse.

Therapy for vasculitis provokes Ca leaching from bones and teeth, which requires an increased intake of low-fat dairy products. With a decrease in the body of Ka - the diet is enriched with dried apricots, raisins, prunes, however, with kidney failure, potassium-containing foods are strictly contraindicated. Vasculitis occurring against the background of anemia requires the introduction of foods containing iron (liver, meat) into the diet.

With vasculitis, remove from the diet grapefruit juice(may alter drug metabolism).

What is the danger of the disease?

The consequences of untreated vasculitis can lead to the following complications:

1. thrombosis and bleeding;
2. syndrome of disseminated intravascular coagulation (DIC);
3. pulmonary and arterial hypertension;
4. nephrotic syndrome and infectious complications.

Treatment of vasculitis is carried out in a complex, so the patient will have to bypass many specialists. Not a single doctor treats, but several, and they advise starting with a rheumatologist, because vasculitis can be a manifestation of autoimmune diseases (rheumatism, lupus). It is not bad to visit a phlebologist, therapist and nutritionist.

Hemorrhagic vasculitis

Hemorrhagic vasculitis is hereditary, systemic disease, manifested by a predominant lesion of capillaries, arterioles, venules, mainly skin, joints, abdominal cavity and kidneys.

From a gene, as from a matrix, encoded information about a disease, in a strictly defined period of a person's life, begins to be read. The information read from the gene region about the disease begins to replace the previously functioning physiological unconditioned reflex for the newly formed pathological dominant unconditioned reflex in the circular memory circuit of the brain memory center. This leads to a gradual change in information in the brain memory center and its replacement with a new one that carries information about the development of the disease. From the brain center of memory, the altered information enters the peripheral center of automatism, where it begins to reshape the physiological unconditioned reflex that existed before the onset of the disease into a pathological dominant unconditioned reflex. Under the influence of different percentage predominance of the dominant pathological unconditioned reflex over the physiological unconditioned reflex, localized in the peripheral center of automatism, there is a formation in varying degrees pronounced, unbalanced interaction of the sympathetic and parasympathetic nervous system. The altered balance in the interaction of the sympathetic and parasympathetic nervous systems gradually leads to a gradual inhibition of the function of the adrenal glands and T-lymphocytes that control the antibody-forming function of B-lymphocytes. B-lymphocytes begin to produce autoantibodies to their own DNA in the endothelium of small vessels of the entire human body. The appearance of vasculitic reactions of the vascular tissue, due to changes in its trophism, causes the gradual emergence of an autoimmune conflict with the formation of antibodies to the own DNA of the endothelium of small vessels, leading to the proliferation of blood through the vascular wall, mainly in the skin of the joints, abdominal cavity and kidneys. There is a gradual launch of the immunoaggressive, immunodestructive essence of hemorrhagic vasculitis, which, by changing the permeability of the walls of small vessels, triggers the autoimmune mechanism of the disease. This is how a targeted, strictly controlled, at the level of information encoded in the gene, mechanism for triggering autoimmune conflicts occurs, leading to the pathology of humoral immunity. The severity of the course of hemorrhagic vasculitis and the activity of the autoimmune conflict that occurs throughout the human body directly depends on the percentage predominance of the dominant pathological unconditioned reflex over the physiological unconditioned reflex that existed before the onset of the disease. Characteristic changes are observed in all walls of small vessels in the form of panvasculitis and capillaritis. Infectious diseases and vaccinations transferred the day before are factors contributing to the earlier onset of the clinical manifestation of hemorrhagic vasculitis.

Clinical picture: The disease is manifested by a triad of symptoms: punctate, sometimes merging hemorrhagic rashes on the skin (purpura), arthralgia (or arthritis) of predominantly large joints, and abdominal syndrome. Initial skin rashes are located on the extensor surfaces of the limbs, sometimes the trunk, end with residual pigmentation, sometimes remaining for a long time. The lower extremities are most commonly affected.

Migrating symmetrical polyarthritis, usually of large joints, is observed in more than 23 patients, accompanied by pain of a different nature - from short-term aches to the most acute, leading patients to immobility. Arthritis is often accompanied by hemorrhages over the affected joints or intra-articular hemorrhage.

Abdominal syndrome (abdominal purpura) is characterized by sudden onset intestinal colic. Pain is usually localized around the navel, but often in other parts of the abdomen (in the right iliac region, right hypochondrium, epigastrium), simulating appendicitis, cholecystitis, pancreatitis. The pains are aggravated by palpation. At the same time, patients have a typical picture of the abdominal syndrome - pallor of the skin, haggard face, sunken eyes, pointed facial features, dry tongue, signs of peritoneal irritation. Patients usually lie on their side, pressing their legs to their stomach, rushing about. Simultaneously with colic, hematemesis, loose stools, often with streaks of blood, appear. The whole variety of abdominal purpura can be put into the following options: typical colic, abdominal syndrome with intussusception.

Often, the kidneys are involved in the pathological process in the form of hematuric glomerulonephritis due to damage to the glomerular capillaries. However, with the outcome of glomerulonephritis in chronic renal pathology can be varied - from urinary syndrome to diffuse glomerulonephritis of hypertonic or mixed type; rarely by the type of nephrotic syndrome. With a general favorable course nephritis, outcomes in chronic progressive nephritis with renal failure are possible.

Laboratory data are not very characteristic - leukocytosis is usually observed, most pronounced with abdominal syndrome, with a shift in the blood formula to the left up to the young. ESR is usually elevated, especially in abdominal syndrome and polyarthritis.

In an acute course, the disease begins suddenly and flows quickly with a multi-symptom clinic of the disease, often complicated by nephritis. Most of the time in chronic we are talking about recurrent skin-articular syndrome. The syndrome of hemorrhagic vasculitis can be observed with infective endocarditis, various vasculitis, diffuse diseases connective tissue.

The principle of healing hemorrhagic vasculitis includes the following points: the first is the termination of the autoimmune conflict in the human body, the second is the restoration in the annular reflex arc the peripheral center of automatism and the brain center of memory of the physiological unconditioned reflex that existed before the onset of the disease, which leads to a balancing of the interaction of the sympathetic and parasympathetic nervous systems. A balanced sympathetic and parasympathetic nervous system restores the trophism of the walls of small vessels, stops the development pathological processes in them. All this automatically leads to the cessation of the development of the disease. The process of curing the disease does not include the process of restoring the already existing changes in the affected joints, small blood vessels at the time of the beginning of the treatment of the disease, which arose as a result of the duration and activity of the manifestation of the existing disease. The practice of curing this disease shows that patients who have previously applied for appropriate help are subject to better cure. In the affected joints and walls of small vessels, there is a gradual increase in the period of remission, in relation to the period of disease activity, which gradually, according to the sinusoidal type of the course of the healing process, leads to the cessation of the development of disease activity. An important sign of a properly conducted treatment process is the disappearance of skin, visceral, articular manifestations of the disease. Visually, the disappearance of skin and articular manifestations of the disease, the patient's well-being gradually improves. The body temperature of a sick person is general and local, in the area of ​​\u200b\u200bthe affected joints it periodically increases, especially at night, then decreases in the future with a tendency to gradually restore it to normal. The activity of the disease through the remitting type of the course of the healing process gradually disappears. The joints, as the activity of the disease decreases in them, begin to acquire the correct shape, the temperature in them decreases, pain syndrome gradually passes. Hemorrhagic rashes gradually decrease on the skin. The process of curing the disease takes place in several courses and requires an average of about three to four months of continuous daily treatment. It depends on the activity and duration of the course of the disease, the severity and aggressiveness of its manifestation. Kidneys affected by the disease, with diffuse glomerulonephritis, can be treated very hard and for a long time with periods of exacerbations and remissions. The development of nephrotic syndrome always aggravates the prognosis of recovery. In the process of treating the disease, the patient should believe and listen only to the doctor conducting the treatment and actively assist him in curing the disease. Practice long-term effects after the treatment shows that patients who have been cured of hemorrhagic vasculitis for a long period of time have no problems with the cured disease. Recovered patients restored their ability to work.

View full version. Vasculitis

Girls, have you watched House? Familiar word?

I, too, in the doctor's office, almost burst out laughing when he voiced this diagnosis as possible.

But it was only a second and rather a nervous reaction.

But in fact, now I am sitting in complete confusion and do not know what to do, because the doctor immediately vividly painted the prospects.

a) we don’t really know how to treat it, although it is treated.

b) they treat where they put us, because we still do not have such a large affected area.

c) they won’t put it there, they won’t put it there, because read paragraph b)

And in general, some kind of crap. And the man howls in pain and is about to lay hands on himself, because he no longer has the strength to endure. wallhead3:

Why did I start the topic myself, I don’t know, suddenly one of you came across methods of treating this rubbish? Not just anoint with something, but with complex treatment?

Maybe you know where to go with it?

We cannot be treated on an outpatient basis, because we don’t have the strength to travel far and even sit in a car.

We need to go to the hospital to get rid of this rubbish once and for all. Well, or to be treated at home, as we can. But this bad option, because they have already recovered, damn it. wallhead3:

True, they were treated for something else, but all the same, the patient no longer has the strength and nerves for experiments. ridaju:

Vasculitis is inflammation of the walls of blood vessels, it may be a manifestation of other diseases, the other day we observed this phenomenon in meningococcal infection, terrible picture. What was your diagnosis - systemic vasculitis? The most commonly prescribed are glucocorticoids, usually prednisone. The main thing is to know the cause and act on it.

We are not given a diagnosis. Doctors look with wild eyes and say they don't know what it is.

They suggested vasculitis, they said that it was necessary to treat it, but they don’t know where.

Start with an examination, take everything you can - a general blood test, urine, blood biochemistry: bilirubin, transaminases, urea, creatinine, alkaline phosphatase, amylase, total protein and protein fractions, rheumatic tests, blood for rheumatic factor, blood glucose, prothrombin index, ECG sure, this is the minimum from which you can “dance”, if the patient cannot make a diagnosis, ask for a consultation with a rheumatologist.

Thank you, Tsilya, that's the only thing they usually start with, and we started a year ago. But the crux of the matter is not where to start. For everything that you described has already been done more than once. We no longer need to be examined, but specifically treated. And not consultations and advice are needed, but real help. A man has not slept for two months because of the pain. Every day is almost on the account, otherwise the roof will go.

Therefore, SPECIFIC experience, not theory, is of interest. Perhaps there are people who have had it. dontknow:

Arti. what is the specific diagnosis? Though ask here http://forums.rusmedserv.com/index.php

here is the best advice to get.

My son at 4.5 years old (now he is 17) had vasculitis, a skin-articular form. I remember this period of my life with condolences. We spent more than six months in the hospital. Bloody smudges on the legs, hemorrhages in the testicles, all the joints are swollen (knees, fingers, even the soles of the feet). What provoked the disease is unknown. In the end, they told me that it was congenital and not treated: ogo. Gradually, the condition began to improve only after a course of prednisolone. But the rashes were still there for about two months (without changes in the joints). And during the whole treatment they put (I don’t even remember the name) a blood-thinning drug, because. It was impossible for us to take blood from a vein. A drop of blood hung on the end of the needle and that's it, they couldn't use a syringe either. required amount take blood. The rheumatologist, an older woman, said. that every 6-7 years there is always a child with such difficult-to-treat vasculitis.

Artie, I wish your relative a speedy recovery, and of course patience.

Lizzy, thank you very much for your experience!

Still prednisolone? We also thought about it.

And a rheumatologist? We rested against this rheumatologist with a horn. there are no doctors. Kick-ass hefty city, but we can't find a doctor! :wallhead3:

But you have confirmed our information. So somehow calmer and more reliable.

Today they pulled me up again early in the morning (and I fell asleep at 6 in the morning, now I’m sitting like a vampire with red eyes), they say, bring me to Moscow and then call an ambulance.

And again he didn’t sleep the night (well, how many people can stay awake? All the resources have already run out), and it seems he agreed to go to the hospital, but when it came down to it, he yells like a fool that he won’t reach Moscow, he can’t sit.

I found a paid ambulance phone. Prices pipets, but already agree to this, if only they were taken and put. But while sitting, rests. Why wait? It won't fall off on its own. wallhead3:

He does not sleep himself, he does not let us sleep either. Everyone's nerves are already frayed. ridaju:

Arti. Prednisolone will be prescribed in any way, and the painkiller does not help at all?

Tsilya, I don't know. Says it doesn't help. But, I think that this is already more at the level of the psyche of sensation. Can't help at all, or at least not make it easier? And it's not like that for him anymore.

Well, two months without sleep and suffering, what kind of psyche can withstand? It may not hurt anymore, but it seems to him that it hurts.

Katya Lyolina

08.08.2011, 16:17

And during the whole treatment they put (I don’t even remember the name) a blood thinning drug

I was diagnosed with vasculitis when doctors with big eyes looked at me and could not understand what kind of disease. Heparin was injected for 2 days. When things got worse, they were sent to regional hospital, there they made a different diagnosis, they also treated with prednisolone.

Arti. then. if the pain is neurogenic, then add pregabalin, or droperidol to enhance the effect of painkillers, but this must be decided by the doctor.

They put me in the hospital. God bless. worthy:

With grief in half, they somehow persuaded me to get there. I didn’t have to call an ambulance, they took me to the surgeon in the clinic, he immediately said that he needed to be hospitalized.

And we are already with an alarming suitcase, with spare shorts, we are standing like soldiers.

And I didn't have to take the ambulance to the hospital. We issued an outfit and drove by car, they accepted it without any problems. And then I called when in one hospital, they immediately and categorically told me, no, they say, we won’t accept by car, call an ambulance and take it.

I called in the evening, my mood seems to be normal, although the first thing they gave me was: “Is it happy that they took me to the hospital?”

Still would! Of course, I’m satisfied, otherwise I already have not one, but both eyes began to twitch. smile:

I really hope that the hospital will help! Highly. worthy:

I'll write what I find out about the treatment. Maybe this will help someone else.

I was diagnosed with systemic vasculitis 5 years ago, my legs were bright red from inflammation, the same thickness from the pelvis to the heels, in order to somehow alleviate it, I smeared it with menthol cream, my legs burned very much, but the cream lasted about 15 minutes, then, like “dandruff”, crumbled with legs, the main treatment - I drank prednisolone for more than six months, then I got off it for 4 months (and a bunch of some other drugs, I don’t remember for a long time), if you’re interested, I have an extract somewhere, I can scan it and send it to the mailer. I don't know if my treatment will help. In general, write in a personal.

Vasculitis is characterized by inflammation of the blood vessels. With this pathology, the condition of the arteries, veins and capillaries worsens, so it poses a considerable health hazard.

Exist the following reasons vasculitis:

• the use of antibiotics belonging to the penicillin series;
• taking antimicrobial agents from the group of sulfonamides;
• hereditary predisposition to the disease;
• dysfunction of the circulatory system;
• hormonal changes in the body;
• the patient has oncological diseases;
• severe hypothermia;
• the patient has rheumatism or arthritis;
• chronic diseases of ENT organs;
• prolonged stress.

Whether or not vasculitis is contagious depends on the form of the pathology. So, the primary form of the disease is not transmitted by contact with a sick person. Secondary vasculitis often occurs against the background of infectious diseases such as hepatitis or syphilis. In this case, infection is possible.

Before answering in more detail the questions of whether vasculitis is dangerous and how to treat the disease, it is necessary to list the main symptoms of the disease. They largely depend on the form of pathology.

Important! At an early stage, the symptoms of the pathology are mild, as a result of which vasculitis is often confused with other diseases. With the progression of the disease, the following symptoms may occur: weakness, pain in the joints, a burning sensation in the affected area, severe itching.

In patients with chronic venous insufficiency, diabetes mellitus and hypertension, the disease is more severe.

Diagnostic measures for vasculitis

Early diagnosis of the disease helps to avoid serious complications.

To identify pathological foci of infection in allergic vasculitis, the following studies are used:

• urine culture;
• analysis of smears from the nasopharynx;
• conducting ultrasound to detect gynecological diseases in women;
• PCR diagnostics;
• RPR test.

Which doctor treats vasculitis

Patients usually ask the following questions: is it possible to cure vasculitis, who should I contact a doctor? If you suspect the presence of this disease, it is recommended to visit a phlebologist. If necessary, the patient will need to consult other specialists:

• dermatologist;
• infectiologist;
• rheumatologist.

Mild disease is treated with outpatient settings. Pregnant women and patients with a severe form of pathology are subject to hospitalization.

If a patient has hemorrhagic vasculitis, a doctor should be observed in order to track the dynamics of the pathology.

How to treat vasculitis - general principles

Doctors of various specialties are engaged in the treatment of pathology. The patient is prescribed appropriate medications. In addition, the treatment of inflammation of the blood vessels involves the following procedures:

• Hemosorption. During the procedure, the blood is purified from toxic substances using a special sorbent. As a result, the nutrition of tissues affected by inflammation of the blood vessels is noticeably improved, and blood circulation is normalized.
• Immunosorption. It comes down to processing venous blood patient using an apparatus filled with immunosorbent.
• Plasmapheresis designed to purify the patient's plasma. There are several types of procedure. With centrifugal plasmapheresis, blood is taken from a peripheral vein. With the help of a special centrifuge, it is divided into plasma and blood cells. After that, the erythrocytes are again transferred into the patient's bloodstream along with special solutions that replace plasma, or plasma from a donor. When conducting membrane plasmapheresis the patient's plasma is purified through a special membrane before returning to the bloodstream. Plasmapheresis is designed to eliminate antibodies, immune complexes and antigens from the blood that provoke the occurrence of pathological changes in the vessels.

Allergic skin vasculitis occurs while taking certain medications or eating certain foods. Therefore, for successful treatment of the disease, contact of the patient with the allergen should be excluded.

Medical treatment

Systemic vascular disease is treated with various drugs. They are presented in the table.

Treatment with folk remedies

Vasculitis also involves treatment with folk remedies. Herbal decoctions and fees reduce the manifestations of an allergic reaction. Folk remedies improve blood circulation, reduce inflammation, and help eliminate toxins from the body.

Medical fee No. 1

Treatment of vasculitis with effective folk remedies will benefit only at an early stage of the disease. The patient can use this simple recipe:

1. For the manufacture of herbal collection, 30 grams of poplar buds, marigold flowers, chopped yarrow grass, mint leaves and elderberry inflorescences are mixed.
2. 1 tablespoon of the resulting mixture is poured into 0.2 liters of hot water.
3. The remedy must be infused for 50 minutes.
4. After this time, the drink is filtered.

You need to drink 50 ml of the product four times a day before meals.

Medical collection №2

In the treatment of inflammation of the blood vessels, a herbal collection is also used, which contains the following ingredients:

• arnica;
• marigold flowers;
• sophora japonica.

10 grams of the resulting mixture is poured into 250 ml of hot water. The product must be infused for at least three hours. It is recommended to take 20 ml of the drink with an interval of 8 hours.

Compresses

With inflammation of the blood vessels, you can make a compress based on black elderberry flowers. Healing solution for the procedure is prepared in this way:

1. You need to take 30 grams of horsetail and chopped black elderberry flowers, 20 grams of mint leaves and yarrow herb.
2. 30 grams of herbal collection must be poured with 400 ml of warm water.
3. The product must be brought to a boil. After that, the fire is turned off.
4. The product must be infused for at least five hours.
5. Then the solution is filtered.

A remedy prepared from black elderberry flowers should be used to apply a compress to the affected areas of the body. The duration of the procedure is 25 minutes.

Tinctures

one more effective method treatment of vascular diseases is a tincture of lemon. To prepare the product, you need to grind one small lemon with a meat grinder. The resulting slurry is mixed with the following ingredients:

• 500 g of sugar;
• 450 ml of quality vodka;
• 10 grams of cloves.

The resulting mixture is transferred to a glass container, carefully sealed with a lid. The agent must be infused in a dry place protected from the penetration of the sun's rays for 14 days. The drink must be stirred daily. After the specified period, the tincture is filtered. It is necessary to use 20 ml of the drug three times a day before meals until the symptoms of vasculitis become less pronounced. The drink should be stored in a cold room in a tightly closed container.

In the treatment of vasculitis, medicinal tinctures are also prepared from the following ingredients:

• hawthorn;
• blueberry;
• ginger;
• nettle;
• turmeric.

Other recipes

Recipe #1

The licorice root contains substances that are similar in their action to glucocorticosteroids. medicinal plant allows you to eliminate the allergic reaction and has an anti-inflammatory effect.

To prepare a decoction of licorice root, pour 10 grams of the roots of a medicinal plant with 200 ml of boiling water. The product is prepared in a water bath for 20 minutes. The resulting broth must be filtered. It is taken 20 ml three times a day thirty minutes before meals.

Recipe #2

If the patient has inflammation of the blood vessels, you can use the following recipe:

1. 20 grams of crushed ginkgo biloba leaves are poured into a glass of water.
2. The agent is thoroughly mixed.
3. The broth is cooked over low heat for five minutes.
4. Then the product must be removed from the stove and cooled.
5. The broth is carefully filtered.

Recipe #3

With inflammation of the blood vessels, you can prepare a healing ointment according to the following recipe:

1. 500 grams of nutria fat is mixed with 200 grams of dried birch buds.
2. The product is placed in a container that is resistant to high temperatures.
3. The mixture must be simmered in the oven at small temperature at least three hours. This process is repeated every day for a week.
4. After this, the agent is filtered and lubricated with it on the affected areas of the body twice a day. The duration of the course of treatment depends on the severity of the disease.

Mode and exercise therapy

With an exacerbation of the disease, a person is shown bed rest. At sharp rise body temperature, the presence of extensive rashes on the body, the patient requires inpatient treatment.

Water procedures for vasculitis are allowed, but it is forbidden to rub the affected areas with a washcloth. Bathing in cool water It is forbidden, because with hypothermia the patient's condition worsens.

Long walks have a negative effect on the affected vessels. As a result, the patient is recommended to be more in a supine or sitting position.

In order to improve blood circulation in the limbs, you need to perform such physical exercises: “birch”, “scissors”, “bicycle”.

With vasculitis, self-massage is performed: it comes down to stroking the legs in the direction from the feet to the knees.

Revascularization

The purpose of revascularization is to restore large vessels. It is performed endovascularly or operational methods. Revascularization is necessary for patients with severe disease that is accompanied by lameness.

With extensive vascular damage, this technique is ineffective. In this case, it is recommended to resort to shunting.

Diet

• salinity;
• fried food;
• dishes that contain mushrooms;
• honey and bee products;
• canned foods;
• chocolate products;
• alcoholic beverages;
• strong brewed tea;
• citrus fruits;
• red-colored apples;
• sweet pastries;
• products containing a large number of flavors, flavor enhancers and dyes.

With a deterioration in kidney function with vasculitis, the patient needs table No. 7, with damage to the digestive tract - table No. 4.

Treatment of vasculitis in children

In children, the signs of the disease are more pronounced. The child's temperature rises to 39 degrees, lethargy and weakness occur. The body weight of a patient suffering from vasculitis decreases, a rash appears in the area of ​​​​the joints, pain occurs in the abdomen, nausea.

In the treatment of children, the same medicines are usually used that are prescribed for adults. The dosage of the drug is set individually. It depends on the weight and age of the child. The basis for the treatment of vasculitis in children are drugs containing glucocorticosteroid hormones. Vitamin-mineral complexes and immunomodulators are usually not prescribed.

In most cases, the treatment of the child is carried out in a hospital. The duration of the therapeutic course varies from three to six weeks. After discharge, the patient is usually registered.

Is it possible to cure the pathology forever?

To understand whether it is possible to cure vasculitis forever, it is necessary to understand that it is not possible to completely control autoimmune processes. Therefore, pathology is considered incurable disease. However, the patient should be promptly contacted for medical care. This will help achieve a long-term remission.

With the timely appointment of cytostatics in combination with glucocorticosteroids, most patients live for more than five years.

The prognosis for vasculitis may worsen in such situations:

• the first signs of the disease appeared rather late: after the patient reached the age of 50 years;
• the patient has a deterioration in kidney function, damage to the nervous system, digestive tract and heart vessels.

What will happen if not treated?

With vasculitis, the blood supply to the tissues near the damaged vessels worsens. In the absence of proper treatment, the disease often leads to disability. In some cases, the patient develops chronic renal failure due to damage to the kidney tissue.

Kidney damage in vasculitis

The patient also has other complications:

• Intestinal perforation. In this disease, the intestinal wall ruptures, its contents are poured into the abdominal cavity. Intestinal perforation is a consequence of the abdominal form of hemorrhagic vasculitis. Due to damage to the vessels to the walls of the organs of the digestive tract does not penetrate enough nutrients, so it loses strength and atrophies. Intestinal perforation can lead to peritonitis.
• Intestinal obstruction. With this pathology, the process of advancing fecal masses is disrupted.
• Bleeding from internal organs. The cause of their occurrence is the rupture of the walls of the large vessels of the patient. With vasculitis, various types of bleeding are observed: intestinal, uterine in female patients, hemorrhage in the testicles in the stronger sex.
• Heart failure. With vasculitis, the strength of the muscle fibers of the patient's heart decreases. They begin to stretch, their gradual deformation occurs. Distinguish the following consequences of vasculitis: myocardial infarction, heart disease, aortic aneurysm rupture.
• hemorrhagic stroke. Cause intracerebral hemorrhage is a rupture of the vessel wall.

Preventive measures

There are no effective preventive measures. To reduce the likelihood of vasculitis, it is necessary to treat such diseases as tonsillitis and adnexitis in time. It is necessary to limit the time spent in the sun. If possible, avoid contact with allergens, strong excitement. Physical activity should be dosed.