Corvalol in large doses how it affects the body. Corvalol: components, how it works, instructions for use, who is indicated, contraindications. Indications for use

"Corvalol" - medical preparation, which is not known outside the countries of Eastern Europe and former USSR. To be more precise, Corvalol is a prohibited drug outside the countries of Eastern Europe and the former USSR.

The history of the creation of "Corvalol" is closely intertwined with the Nazi past of Germany. Military doctors of that time were looking for a super-medicine for a long time that would increase the combat capability of the army, relieving the soldiers of the fear of the upcoming battle.

After many studies, a drug was created, which was based on a synthetic drug - luminal. The new remedy had the ability to quickly eliminate anxiety, nervous tension and fear.

Harm "Corvalol"

Today, the composition of Corvalol, beloved by our parents, also includes luminal, only it is called differently - phenobarbital. It is this component that puts Corvalol on a par with drugs. Phenobarbital belongs to the group of barbiturates, which are extremely dangerous when taken with alcohol.

Also, barbiturates tend to accumulate in the body, which is why patients may experience chronic daytime sleepiness. When the drug is abruptly discontinued, patients experience increased anxiety, nervous tension and palpitations.

Reception "Corvalol" long time leads to deterioration of the liver, kidneys and other organs. Also, the systematic use of the drug negatively affects memory, sleep and emotional condition person.

Dependence on Corvalol primarily threatens our grandparents. It is not surprising that a penny preparation has become for them a cure for all diseases. Old people take it for excessive anxiety, heart palpitations and pain in the heart, dizziness and more ...

Indeed, "Corvalol" soothes, relieves pain and nervous tension, helps to fall asleep quickly. But at long-term use drug, its effect is reduced. Therefore, in order to achieve strong effect old people have to drip more and more funds. Often pensioners manage to drink a whole bottle of Corvalol in a day!

Still, it cannot be said that Corvalol is a bad drug. But it should only be used extreme cases 15-30 drops 3 times a day. The drug can not be used for months! Corvalol is also indicated as a sleeping pill at night, but it is better to replace it with another herbal preparation.

To relieve heart pain that occurs with excessive action of a psychotraumatic factor or a violation hormonal regulation body, insomnia, a drug such as Corvalol is prescribed. It is used for complex treatment hypertension, vegetative dystonia, mild spasm coronary arteries hearts.

Read in this article

Does Corvalol help with pain in the heart

At pain attack and increased heart rate, a single dose may be increased to 40 or 50 drops. It should be noted that for elderly patients and in case of impaired liver function, the excretion of the drug is impaired, therefore daily dose should not exceed 50 - 60 drops.

With prolonged use, accumulation of Corvalol in the tissues is possible, which leads to toxic effects. Therefore, the drug is not recommended for permanent use, and the attending physician should prescribe the exact dose and duration of the course of therapy.

Restrictions on taking Corvalol

The drug is not prescribed for children under 18 years of age, during pregnancy and lactation.

Side effects of Corvalol

Long-term therapy with Corvalol leads to the development of dependence on the drug, with its abrupt cancellation it is possible withdrawal syndrome with motor excitement and increased irritability.

High doses cause intoxication, which is manifested by such clinical symptoms:

suppression of breathing, up to a complete stop;
coma;
violation of the heart rhythm by the type of bradycardia;
drop in blood pressure, ;
low body temperature;
decrease in urine output.

When treating with Corvalol, you should not take alcoholic beverages, drive a car, work in production with mechanisms that require a quick motor reaction or increased concentration of attention. With the simultaneous use of drugs such as Aspirin, Indomethacin, Diclofenac, the risk of ulcerative lesion mucous membrane of the stomach.

Validol or Corvalol for pain in the heart - what to choose?

The use of Validol and Corvalol is indicated for pain in the heart, which is not associated with blockage coronary vessels, inflammatory or dystrophic processes in the myocardium. With these diseases, taking such drugs will not have a therapeutic effect.

If an attack of pain lasts more than 30-40 minutes and its intensity does not decrease, then you need to urgently call ambulance. Before she arrives, you can take an aspirin tablet and 2 nitroglycerin tablets at intervals of 15 minutes. At high blood pressure take 1 tablet.

For pains in the heart that are associated with neurosis or stress, sedative drugs are prescribed, which include Corvalol. Its reception relieves vasospasm and causes inhibition processes in the cerebral cortex. Not recommended uncontrolled use without a doctor's recommendation. Contraindicated in violation of the function of the liver, kidneys, medicinal or alcohol addiction. Large doses cause poisoning.

If there is no effect from taking with an attack of heart pain, you need to urgently see a doctor for an exception acute violation myocardial blood supply.

Main contraindications, method of application

Harm from Corvalol occurs when it is given to children, especially up to the age of three years. After three years, the medicine is given only in case of urgent need and always after agreement with the doctor.

To date, there is no accurate data on the effects of drops on the body of pregnant and lactating women, on intrauterine development fetus. Therefore, during this period, women need to give up drops, the doctor will prescribe a more suitable medicine.

The drug is dangerous for craniocerebral injuries, a number of brain diseases, confirmed alcohol dependence. So the most dangerous will be the use of the drug when severe violation the work of the kidneys and liver, for example, with cirrhosis of the liver and renal failure.

Peppermint oil can cause:

allergic reactions;
disruption of the digestive tract.

Therefore, people with a tendency to allergies should not use a sedative. In particular rare cases such intolerance provokes severe complications, such patients are advised by doctors to take analogues of the remedy.

Side effects are aggravated at times if alcohol is consumed along with drops. Even a small amount of alcohol in the blood causes an increase in blood pressure, an acceleration of the heartbeat, and excessive excitability.

The drug after drinking alcohol only partially eliminates the symptoms, but at the same time deals a powerful blow to internal organs and systems. There is also an increased risk of addiction, development drug addiction. AT severe cases develops the so-called delirium tremens, the person suffers from hallucinations, epileptic seizures.

Prolonged use threatens with bromine poisoning, pathological condition accompanied by apathy, rhinitis, impaired coordination of movements, inflammatory process In eyes.

The dosage of sedative drops that will not cause harm and give the expected effect is determined by the doctor. The instructions for use indicate:

adults take 30 drops at a time;
children from 3 years old give 1 drop for each year of life.

If an adult is diagnosed with tachycardia, the doctor advises using up to 40 drops of the remedy. During the day, a sedative can be drunk no more than 3 times. As for children, repeated use of the medicine is allowed, but it is harmful to prescribe drops to your child on your own.

The duration of the course should be determined depending on the diagnosis, age and characteristics of the patient's body. Self-prolonging treatment is dangerous to health.

Cases of overdose, side effects, interaction

Even though the sedative is safe, it can cause adverse reactions organism. These include increased drowsiness, frequent dizziness, slow heart rate, decreased concentration.

It must be taken into account that long-term use drops causes a phenomenon such as bromism, when addiction develops, dependence on the drug, as well as a withdrawal syndrome. If any symptom occurs, you must consult a doctor and stop taking it. As a rule, in this case, the treatment regimen is adjusted or the dosage of the drug is reduced.

There will be no benefit if you take too much sedative, with an overdose, the level decreases blood pressure, coordination of movements is disturbed, the central nervous system is depressed, rhinitis, ataxia, hemorrhagic diathesis develops.

caffeine;
Niketamide.

Forbidden to take soothing drops if the patient is already taking any sedative, both drugs will enhance the effect of each other, an overdose will occur.

Corvalol is able to affect the central nervous system, since it contains ethanol and phenobarbital. After the use of drops, it is forbidden to drive a motor vehicle, carry out work associated with increased concentration attention.

Any means of a central depressant type enhance the effect of sedative drops. The presence of phenobarbital induces liver enzymes, therefore, parallel use with such agents is undesirable:

coumarin derivatives;
oral contraceptives;
glucocorticoids.

Otherwise, due to an increase in the metabolic rate, their effectiveness decreases.

The drug enhances the effect local anesthetics, sleeping pills and painkillers, which is associated with the presence of barbituric acid derivatives.

So is it good or bad?

There is an increasing debate about how harmful Corvalol is, what benefits and harms it can have for the body. Some time ago, information was spread that they wanted to ban Corvalol in our country, but this remained only at the level of rumors, the drug is still on the pharmacy shelves.

However, sedative drops remain banned abroad, the import of the drug is tightly controlled by the state. Our habit of using Corvalol is so strong that withdrawing it from sale will cause a storm of negative emotions.

At the same time, the drug will gradually be replaced by more modern drops and tablets with proven efficacy and a minimum of adverse reactions. Phenobarbital has a negative effect on the psyche, causes extremely rapid addiction, psychological and physical dependence.

If you abruptly stop taking the medicine, a person develops the so-called withdrawal syndrome, the patient complains of:

intense pain in the head;
depressed state;
constant nausea.

Few people know that phenobarbital is used in some countries to carry out the death penalty.

If within years the drug was used by millions of patients, in the bulk of cases negative consequences did not arise, is it really so harmful to the body? The undeniable advantage of soothing drops is a quick and most powerful effect.

When used in small recommended doses, the drug instantly removes the feeling of anxiety, normalizes heartbeat. With reasonable use, the drops are not dangerous, with regular immoderate intake, it becomes necessary to increase the dosage each time.

The danger lies not in the dose itself, but in getting real euphoria after using Corvalol, the benefits or harms are obvious.

When a person has the listed adverse reactions, relatives have noticed mood swings after using the medicine, it is important to seek medical care. Drug dependence is treated already in specific medical institutions.

Perhaps there is no other soothing and cardiac remedy, which would be as popular as the well-known Corvalol. Even in the 21st century, many people, especially the older generation, consider it the best remedy from pain in the heart, insomnia and feelings of anxiety. Almost 100 years active use remedies in medicine should speak in its favor, but many patients wonder whether Corvalol is harmful to health and whether its use in treatment is always justified. To answer this question, you need to consider all the positive and negative aspects of this tool.

Composition and action of the drug

Forms of release of this drug - tablets and drops. Greater popularity ever since Soviet Union Drops have always been used. Speaking about the benefits and harms of Corvalol, you need to familiarize yourself with its composition. It includes ethyl bromoisovalerianate, phenobarbital, sodium hydroxide, peppermint oil, purified water.

Corvalol in drops is a colorless liquid with a specific pungent odor. The first two ingredients in the composition of the product have a calming and antispasmodic effect, relieve excitement and nervousness, provide a strong and restful sleep. Extract peppermint dilates blood vessels, including those in the heart muscle, positive influence on intestinal peristalsis.

The components of the drug are optimally combined and complement each other's action. The use of Corvalol is indicated in the following cases:

increased irritability, excitability, anxiety;
insomnia against the background of emotional experiences;
tachycardia;
the presence of spasms in the gastrointestinal tract;
elevated arterial pressure on the early stages diseases.

It would seem that the benefits of the drug are undeniable, but one cannot fail to note a rather impressive list of contraindications for use.

There are frequent cases of individual intolerance to individual components of the drug. In this case, Corvalol can be dangerous to the body. Doctors do not recommend Corvalol to patients with renal and liver failure as well as under reduced pressure. In the latter case, Corvalol can bring the pressure to a critical point.

Pregnant women should be especially careful when taking the drug. Phenobarbital provokes the occurrence of hypoxia and irreversible disorders in the central nervous system of the unborn child. Corvalol is especially dangerous in the first three months of pregnancy. Thus, its use is permissible only in extreme cases and should be under the supervision of a physician.

Harm from Corvalol can be experienced by children under 12 years of age. Its reception is possible only if the child suffers severe moral experiences and traumas. But even with such a diagnosis, taking Corvalol should not be long-term and eventually replaced by an analogue.

Of great importance when taking Corvalol is the dosage. Since the drug is perceived by many people as a harmless remedy, the number of drops may not be controlled. Before deciding whether to use Corvalol as a medicine, it is imperative to determine the allowable dosage with your doctor. Otherwise, taking drops can lead to an overdose.

Overdose and side effects

To have a clear idea of how dangerous Corvalol is, you need to know the symptoms that occur during an overdose and poisoning with this drug. A dangerous dose of the drug is 150 drops, but in the elderly, debilitated patients and children under the age of 12, poisoning can occur at lower doses.

There are three forms of poisoning: mild, moderate and severe intoxication. With a slight overdose, there are general weakness, absent-mindedness and drowsiness of the patient. The patient's condition does not require any treatment and stabilizes after the end of the drug.

With moderate and severe poisoning, the patient has the following symptoms:

muscle weakness;
a sharp drop in blood pressure;
dilated pupils;
pathological sleepy state, the patient cannot be awakened;
loss of consciousness;
wheezing in the lungs;
cyanosis skin faces;
malfunctions of the cardiovascular system.

In a severe form of intoxication, coma and even death are possible.

At correct dosage drug side effects occur very rarely and are of a slightly pronounced nature. There is dizziness, general weakness, drowsiness in the daytime.

Corvalol tincture is often used as a drug to eliminate the symptoms of a hangover. Because alcohol itself causes heart palpitations, muscle weakness and increased excitability, in combination with Corvalol, these symptoms only get worse.

Also dangerous and highly undesirable simultaneous reception corvalol with tranquilizers and sedatives. double dose medicines causes backlash organism.

Habituation and dependence on Corvalol

Phenobarbital and ethyl bromisovalerianate can be considered as drugs. With regular use of Corvalol as a sedative and sedative, the patient quickly becomes addicted to the drug. You can talk about a certain degree of addiction even after two or three weeks of regular use of the remedy.

Gradually, the standard dose ceases to bring desired effect, which leads to the need to increase the dose, which, in turn, causes health risks. In the future, the drug accumulates in the body, so even the usual dose can cause phenobarbital poisoning.

It should be noted that sleep caused by a significant dose of Corvalol is often restless and does not bring a feeling of cheerfulness upon awakening.

The harm from Corvalol also lies in the development of addiction to the drug. The patient feels chronic fatigue, is in a depressed apathetic mood, speech and concentration may suffer.

Help with poisoning

If the symptoms of poisoning are insignificant, the patient needs gastric lavage. After the procedure, it is desirable to take one of the sorbents: activated carbon, smecta. Activated carbon prevents absorption toxic substances into the bloodstream and accelerates their excretion from the body. The remedy is best taken as aqueous solution. To do this, the tablet must be crushed and mixed with 100 ml boiled water room temperature. It is possible to use white activated carbon.

Recommended for poisoning cleansing enemas. The victim must be provided plentiful drink, warm sweet tea is better than other drinks. It is necessary to normalize reduced pressure and replenish lost glucose stores.

At mild degree poisoning, these measures are usually sufficient. In case of moderate and severe poisoning, a mandatory measure should be to call an ambulance.

If the patient is unconscious, he is placed on hard surface, loosen belts and belts, remove all jewelry that restricts movement and prevents free access of air. Before the arrival of doctors, it is necessary to monitor the state of the patient's pulse. With a severe degree of poisoning, a heart massage and an artificial respiration procedure are required.

To stabilize the condition in case of Corvalol poisoning, it is necessary intravenous administration antidote drug - bemegride. In most cases, moderate and severe forms of poisoning are treated in a hospital setting. The patient will need the help of a therapist and a gastroenterologist. Treatment in specialized institutions involves the introduction of glucose, sodium chloride, plasma and diuretics. With a significant concentration of phenobarbital in the blood, hemodialysis may be necessary.

Consequences of corvalol poisoning

Severe poisoning may be further complications for the body. Subsequently, there may be allergic reactions on the skin in the form of rashes, burning and itching. Also, there are frequent pathologies of the liver and kidneys, disturbances in the work of the central nervous system, high risk heart attack and stroke.

Severe poisoning in a child can even be fatal.

The benefits and harms of Corvalol should be considered when choosing a dosage. At neurological diseases the number of drops should not exceed 15-20, with nervous states- 10-15, to relieve pain in the heart - up to 40 drops. The number of doses should not exceed 3 times a day.

Careful adherence to the dosage of the drug, prior consultation with the doctor, careful use of the drug will contribute to effective action corvalol without negative consequences for the body.

Corvalol is a drug that has a sedative and hypnotic effect. Indications for its use are:

intestinal spasms;
initial stages of hypertension;
insomnia;
tachycardia;
angina pectoris (in combination with nitrates);
neuroses with increased irritability.

Source: serdcelechim.ru

Corvalol helps relieve nervous tension, eliminate the effects of stress, improve sleep. That is why it is often taken by many people, and often without a doctor's prescription. But the composition of this drug includes phenobarbital and long-term uncontrolled treatment with it leads to the formation drug addiction causes a life-threatening overdose. Therefore, in the EU and the USA, this remedy is sold in pharmacies only by prescription. Unfortunately, in Russia and the CIS countries Corvalol can be purchased by anyone and therefore cases of overdose are quite common.

For adults, Corvalol is usually prescribed 15-20 drops three times a day. And only in case of severe tachycardia, up to 40 drops can be taken once.

Over time, patients develop addiction to Corvalol and usual doses medicinal product cease to have the desired effect. As a result of this, they begin to take it in large dosages and much more often. If you take 10 ml of Corvalol, which corresponds to half a vial, within a short time period, this will lead to overdose symptoms.

An overdose of Corvalol can also develop when taking low doses of the drug. This is observed when it is combined with alcohol, tranquilizers, antidepressants or sedatives, as they potentiate, that is, enhance the inhibitory effect of the drug on the central nervous system.

Long-term treatment with Corvalol can cause not only the formation of drug dependence, but also a chronic overdose of the body with ethyl bromisovalerianate, which also leads to a number of pathological changes.

Signs of an overdose

An acute overdose of Corvalol occurs when a person accidentally or intentionally during short span time takes a very high dose of the drug, much higher than the therapeutic.

Acute overdose of mild Corvalol usually manifests itself:

drowsiness;
weakness;
dizziness;
decreased concentration and performance;
movement coordination disorders.

For an overdose of Corvalol medium degree gravity is characterized by the following symptoms:

deep sleep, in which it is possible to wake a person with great difficulty;
rapid heart rate (tachycardia).

With a severe overdose of Corvalol, the condition of patients worsens significantly. They are observed:

violations correct rhythm hearts;
rapid shallow breathing;
a sharp decrease in blood pressure;
muscle twitching, turning into generalized convulsive seizures.

Source: depositphotos.com

Pronounced hypotension becomes the cause of the development of a collaptoid state in the patient, which later, against the background of increasing hypoxia of organs and tissues, passes into a coma. If the patient is not provided with urgent medical care, then a fatal outcome may occur.

Chronic overdose of Corvalol, or rather ethyl bromisovaleriant, which is part of it, manifests itself:

indifference to the surrounding reality;
depressive state;
confusion of consciousness;
conjunctivitis;
rhinitis;
the appearance of acne.

Long-term treatment with Corvalol leads to the formation of drug dependence, which is associated with the phenobarbital contained in the drug. Its presence can be assumed on the basis of the following signs:

depressed mood;
tired look;
self-doubt;
impaired concentration;
inadequate reaction to loved ones.

The intensity of the severity of these signs significantly weakens after taking the next dose of Corvalol.

First aid for overdose

At acute overdose Corvalol, you must first perform a gastric lavage. The patient is offered to drink about one liter pure water, and then, by pressing the fingers of the hand on the root of the tongue, cause him to vomit. This simple procedure should be performed at least 3-4 times in order to thoroughly cleanse the stomach of the remnants of the taken Corvalol.

After gastric lavage, the patient is allowed to take one of the sorbent preparations. It can be Smecta, Enterogel, Filtrum STI or Activated carbon. They absorb the digestive tract Corvalol and hold it, preventing it from being absorbed and entering the bloodstream.

In case of an overdose of Corvalol, it is necessary to try to maintain contact with the patient, preventing him from falling asleep. If not severe vomiting, then it is necessary to often give a poisoned person a drink, as this will increase the amount of urine separated and thereby accelerate the removal of Corvalol from the body.

With a chronic overdose of Corvalol or the development of drug dependence, the first first aid is to stop further use of this drug.

Antidote

There is no specific antidote for corvalol.

When is medical attention needed?

Even with mild degrees of overdose of Corvalol, you should definitely seek medical help, since at any time the condition of the victim may suddenly and dramatically worsen. Moreover, a visit to a doctor is necessary in case of an overdose of moderate and severe Corvalol.

In a hospital, patients with an overdose of Corvalol undergo gastric lavage using a gastric tube and begin symptomatic therapy aimed at preventing the development or restoring existing dysfunctions cardiovascular system and respiratory failure.

For the speedy removal of Corvalol from the body, forced diuresis is performed with alkalization of the blood with sodium bicarbonate solution, hemosorption and / or extracorporeal hemodialysis.

In case of severe respiratory failure, tracheal intubation is performed and the patient is transferred to artificial ventilation lungs.

For the treatment of chronic overdose of Corvalol, abundant salted drinking and the use of diuretics (Lasix, Veroshpiron, Hypothiazid) are indicated.

Therapy of drug dependence on Corvalol requires long-term therapy, which is carried out jointly by toxicologists, narcologists and psychotherapists.

Possible Complications

Severe degrees of overdose with Corvalol are quite dangerous. They may end lethal outcome even if prompt medical attention is provided.

An overdose of Corvalol is often complicated by pneumonia, impaired renal function. AT remote period neurological disorders (depression, wobbly gait), which are caused by toxic and hypoxic encephalopathy.

In the elderly, chronic overdose can cause:

reducing the reaction rate;
memory impairment;
difficult thinking;
impaired coordination of movements.

All of the above often leads to falls in older people, which can lead to fractures.

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