Grandaxin or Atarax or Phenibut - which is better? Is it suitable for pediatric therapy? Which is better: Atarax or Grandaxin

It is common for every person to experience a feeling of fear, anxiety, and anxiety at certain moments. These emotions are natural reaction for events of a certain kind: public speaking, passing the session, worrying about loved ones.

But, it is quite another matter if these emotions become difficult to control. They haunt a person constantly, becoming sources of various anxiety and depressive conditions.

Such disorders require medical correction. Of the drugs prescribed by specialists to eliminate uncontrolled pathological reactions nervous system, Atarax and Grandaxin can be distinguished.

"Atarax": a description of the drug

anxiolytic(tranquilizer) non-benzodiazepine series. It is used to treat neurosis, eliminate feelings of anxiety, alleviate the symptoms of psychomotor agitation.

In addition, the drug has sedative, antihistamine and antiemetic effects. Improves the quality and overall duration of sleep.

The drug is produced in two forms: film-coated tablets, ampoules for intramuscular injections.

The main active ingredient is hydroxyzine. In tablets, its content is 25 mg in each piece. In an ampoule solution of 100 mg per 2 ml.

In the form of ampoules, the drug is used in the clinic.

Indications and contraindications

The assignment is shown under the following conditions:

• Chronic alcoholism.
• withdrawal syndrome.
• postpartum depression.
• Neurosis, accompanied by strong excitability, anxiety, emotional stress.
• Skin itching with dermatitis, eczema, psoriasis.

As a sedative, Atarax is used before preparing for surgical operations.

After surgical interventions, it is used as an antiemetic.

Contraindications are: pregnancy, lactation period, intolerance to components, impaired absorption of galactose, porphyrin disease, glaucoma, age up to 1 year.

Side effects are manifested by a decrease in blood pressure, nausea, constipation, headache, general weakness and fatigue, blurred vision, fever.

This medication is produced in Belgium by the pharmaceutical company USB Pharma. Available in pharmacies by prescription.

"Grandaxin": a description of the drug

"Grandaxin" - class tranquilizer benzodiazepine derivatives. It differs from classical benzodiazepines in its atypical chemical structure.

His main active ingredient – tofisopam is an atypical derivative of diazepam. The molecular formula of the drug has been changed in such a way that it does not contain the properties of classic benzodiazepines. negative manifestations as the development of addiction, withdrawal syndrome.

The drug has an anxiolytic effect, without having a sedative and muscle relaxant effect. It is a daytime tranquilizer.

The action of the drug is aimed at eliminating various violations activity of the autonomic nervous system. It also has a stimulating effect on the body.

Produced "Grandaxin" only in the form of tablets. One tablet contains 50 mg of tofisopam, the main active ingredient.

Indications and contraindications

Indications for use are:

• Asthenic syndrome.
• Neurasthenia.
• Neuroses and neurosis-like states.
• Severe PMS.
• Psychovegetative disorders.
• Panic and anxiety states.
• Asonmias provoked by neurological causes.
• climacteric syndrome.
• somatic disorders.
• Cardialgia of neurotic origin.
• withdrawal syndrome.
• Unmotivated fear.
• Myasthenia gravis and myopathy with neurotic symptoms.

Given the ability of the drug to stabilize the psychological balance, it is often used in the prevention of prevention. panic attacks.

Contraindications to the appointment are:

1. Sleep apnea.
2. Respiratory failure syndrome.
3. Early pregnancy.
4. lactation period.
5. Hypersensitivity to any of the components of the drug or other benzodiazepines.
6. Psychopathological states accompanied by aggressiveness, motor-speech excitement.
7. Severe depression.
8. Lactase deficiency.
9. Galactose intolerance.
10. Concomitant use of immunosuppressive drugs.

Children and adolescents under 18 years of age are not prescribed medication due to the lack of sufficient experience in this age category.

Side effects may include: irritability, dizziness, sleep disturbance, headaches, loss of appetite, work disturbance digestive system, drying of mucous membranes oral cavity, allergic reactions, disruption of the liver, myalgia.

The drug is manufactured in Hungary by a pharmaceutical company EGIS Pharmaceuticals. Released by prescription only.

Drug Similarities

The similarity of the presented medicines can be traced in their belonging to the same group - tranquilizers.

Also united by their absence negative impact on cognitive functions.

They are not developed drug addiction, even when long-term use. Both pharmaceuticals are successfully used in therapy. neurotic states. Both have a prescription.

The drugs are similar in cost. "Atarax" - from 283 rub. up to 360 rublesfrom 300 rub. up to 350 rubles.

What are the differences

The difference parameters are as follows:

1. Possess absolutely different composition and mechanism of action.
2. They differ in producing countries.
3. "Atarax" has a pronounced sedative effect. The second remedy does not have such an effect.
4. Grandaxin has a wider list of indications. But he also has more "side effects" than the Belgian medicine.
5. "Atarax" is allowed to appoint children from 1 year. "Grandaxin" only from the age of 18.
6. Taking a Belgian Pharmaceutical Provides Management Restrictions vehicles and performance of work related to the speed of response.
7. The Hungarian drug is stronger in pharmaceutical action.

What is better to choose

Competently say which of the drugs is better, only a specialist can. Each of them has both pluses and minuses. And they are prescribed in different clinical cases.

"Atarax" acts softer and is better tolerated by patients. It is chosen for the treatment of anxiety or depressive lung conditions degree.

It should also be preferred for treatment emotional disorders that appeared in the background mental illness or brain pathology.

"Grandaxin" must be chosen when functional disorder autonomic nervous system. In other words, when there is no specific pathology, but only the activity of nervous structures is disordered.

In some cases, according to the doctor's prescription, it is possible to take anxiolytics together. Grandaxin is used in daytime to relieve anxiety sedative effect, "Atarax" drink in the evening, to improve sleep.

But, in each case, the dosage is selected strictly individually, and the intake of both tranquilizers is carried out under the supervision of the attending physician.

• cellulose microcrystalline;
• colloidal silicon anhydride;
• magnesium stearate;
• lactose monohydrate.

The drug is used for psychomotor agitation, with increased irritability of a neurological nature, with chronic alcoholism, for skin itching and as a sedative.

Atarax is quite popular, but still it may not be suitable for treating a patient for some parameters, so they are looking for analogues of the drug, so the question arises: “What can replace Atarax?”.

Which is better - Atarax or Teraligen?

First of all, it should be noted that Teraligen is an antipsychotic drug, therefore it is used to treat various diseases nervous system, including mental disorders, depression, neurosis, and allergic reaction. From which we can conclude that Teraligen has more wide range effects than Atarax, while it eliminates any manifestation of allergies, and Atarax - so much from itching, which means it is more effective.

Which is better - Atarax or Adaptol?

Adaptol is a tranquilizer and is used to symptomatic treatment, restoring sleep, cardialgia and to improve the patient's tolerance to antipsychotics and tranquilizers, and is also used in the treatment of neuroses. Indications for the use of drugs have differences, but the specifics are similar, so each of the drugs has its own advantages, which are taken into account when choosing a medicine. Therefore, it is difficult to answer the question of which of the drugs is better, since their purpose is different.

What is better Atarax or Phenibut?

Phenibut is used for asthenic and anxiety-neurotic conditions, psychopathy, fears and obsessive states. It also helps with insomnia and nightmares. In some aspects, the indications for the use of Atarax and Phenibut are the same, but their contraindications are significantly different. So, the first is not recommended for porphyria, pregnancy, lactation, labor activity and hypersensitivity to the components of the drug, and the second only in case of intolerance to phenibut. Therefore, choosing between two drugs, the scales are shifted towards Phenibut, in which the list of contraindications is much shorter.

Which is better - Atarax or Grandaxin?

Grandaxin tablets are intended for the treatment of:

• neuroses;
• depression;
• stress;
• premenstrual tension syndrome;
• syndrome alcohol withdrawal;
• cardialgia.

In contrast to this drug, Atarax has a narrower profile and does not treat diseases, but its manifestations or initial stages so for the treatment complex diseases, the doctor most likely will prescribe Grandaxin.

But still, you should not make a choice between Atarax and its analogue on your own, it is better to contact a specialist.

What is better phenibut or atarax

Girls which is better, phenibut

Phenibut is very strong drug, and then it is very difficult to “remove” a child from him and whims + tantrums can only become more.

These are, in principle, antidepressants ... Light. Kids don't really need...

Totally opposed to this crap.

Neurologist. Phenibut and Atarax.

To be honest, I personally don't positive feedback I haven’t heard from taking Glycine. Does it really work or is it just doctors pushing this garbage? We were prescribed phenibut, took it, but the effect was only during the reception. We stopped taking it and hello again!

Yes, and the problems were a little different, a sedative medicine was prescribed to make glycine

But I already read that it did not help you

Emotional day! What sedatives did the neurologist prescribe for your children?

About medicines - I will not prompt.

About children and you - in your family there is neither calmness nor consistency - therefore everyone is nervous and no one can cope with anyone. Children do not have an authoritative adult, and there is no model of behavior, that's chaos everywhere.

Timokha also goes to the clinic, but if you can't, then you can't. And I talk and explain - yes, he has no idea to climb under the bench to tear something off, for example. He's at the window will go better watch, well, or say hello to animals painted, and look at flowers

How long have historians been? My daughter had such a period, I want to compare. And what was the reason for all these complaints initially? difficult childbirth, pregnancy? Sorry for asking questions, I just didn’t treat my daughter with neurology, now my son is next in line, I still don’t know what to do with him

Eh, what kind of kids have gone with us ... The same youngest gives heat (the crisis and the garden also adds this one with his adaptation). Glycine and Tenoten were prescribed to the middle one (bad sleep and terribly gnashed his teeth at night) ... Let's hope only for the best that we still remains.

What is better Phenibut or Atarax?

Excessive anxiety and worry often make people think about taking psychotropic drugs. But sometimes it's hard to make a choice. How to determine which is better, Phenibut or Atarax, which drug to give preference to, and whether they can be combined - these questions are of concern to many.

According to doctors, when choosing a medicine, one should pay attention to its purpose, and correlate it with the purpose of treatment, as well as the list of contraindications.

Purpose of Phenibut

The drug Phenibut is a representative of the nootropic pharmacological group. Therefore, the compatibility of Atarax and Phenibut is beyond doubt - these drugs belong to different pharmacological groups and complement each other perfectly.

Available in the form of tablets with a dosage of 250 mg and powder with a dosage of 100 mg.

Nootropic activity and tranquilizing effect of the drug Phenibut are due to the active substance in its basis - a phenyl derivative gamma-aminobutyric acid and phenylethylamine, as well as dopamine-positive components.

The use of Phenibut has a psychostimulating, antiplatelet and antioxidant effect. The drug effectively relieves feelings of anxiety and fear, improves sleep, and also stimulates brain activity, normalizing blood circulation and metabolic processes in his tissues.

According to the instructions, the main indications for taking Phenibut:

• asthenic conditions;
• alcohol syndromes;
• insomnia;
• motion sickness prevention;
• need for improvement mental activity, concentration and memory.

The drug is addictive and can only help within the course specified in the instructions. Otherwise, the therapeutic effect will gradually become weaker.

Purpose of Atarax

Atarax is classified as an anxiolytic agent that suppresses emotional stress and neurosis. The drug is based on the active substance hydroxyzine dihydrochloride, a derivative of diphenylmethane, which provides a sedative and antihistamine effect.

• aggressive conditions - irritability, agitation, neurosis, as well as dizziness, neurotic disorders;
• alcohol syndromes;
• dermatological lesions accompanied by itching.

If you take Phenibut and Atarax at the same time, then their interaction will provide an increase therapeutic effect even without increasing the dose.

Atarax is contraindicated in patients who take alcohol, are prone to convulsions, arrhythmias, increased intraocular pressure, difficulty urinating, as well as pregnant women and patients with hyperplasia prostate.

Reception of Atarax is not addictive and is rarely accompanied by adverse reactions.

What is common and what is the difference

Both Phenibut and Atarax do an excellent job with neuroses and anxiety states, influencing nervous system, but at the same time, without oppressing her. Unlike Phenibut, Atarax does not cause irritation of the gastrointestinal mucosa, but it is not able to help with insomnia.

Phenibut has a lasting effect if concentration and memory are needed, but is not able to help patients with itchy dermatological diseases.

The combination of Atarax and Phenibut is the optimal solution to several problems at once. Therefore, doctors often prescribe simultaneous reception drugs.

To date, pharmacies have several analogues of Phenibut and Atarax, created on the basis of the same active substances. If you are allergic to the components of the drug, you can choose a substitute for Phenibut. similar medicinal properties have drugs from the same pharmacological group - tranquilizers Adaptol, Afobazol, Grandaxin.

Found an error? Select it and press Ctrl + Enter

Is it possible to replace atarax with phenibut?

Asks: Oleg:06:02)

Hello. Tell me please, I recently visited a psychotherapist. He prescribed me atarax and pantocalcin for a month. He said atarax would help right away, but from him severe drowsiness which does not go away. I am 17 years old. I suffer from VVD due to mixed type+ gastroduodenitis Hp +. They said that I have a psychasthenic personality type. I am constantly sick and can’t cope with it. I was in the hospital 3 times, 2 of them in gastroenterology. I have a very anxious personality. and phenazepam. I didn’t take phenazepam because this medicine is given in a durke and it’s addictive. But I don’t remember, I seem to have taken it, but I don’t remember what it seemed to help. Now tell me please, can I take phenibut instead of atarax?

Hello Oleg. I think that in such a situation, it is more expedient for you to turn to a psychotherapist who already knows you, observes you and sees the dynamics of the state. Discuss this issue with him, it may be worth reducing the dosage of the drug. both drugs can cause drowsiness.

Ekaterina Vladimirovna, Nizhny Novgorod, skype consultations

Oleg, in general, the doctor should really prescribe the treatment, but keep in mind that "atarax" is a tranquilizer, and "phenibut" belongs to another group. According to your descriptions, Phenibut is really more suitable for you, which has a calming (with anxiety disorders), but not relaxing. If your condition is relatively stable and there are no panic attacks, you can try this scheme, just consult your doctor about the correct dosage, this is very important. "Phenazepam" is not taken "in a fool", it is just a sedative drug that does not cause a withdrawal effect, as a rule. But in general, with a psychoasthenic personality type, anxiety, psychosomatic illnesses(VSD, gastroduodenitis) you are shown psychotherapy, keeping a diary, good mode days and preferably physical exercise- it will increase the stamina of your nervous system.

Golysheva Evgenia Andreevna, psychologist Moscow

Elektrostal Parents Portal

Phenibut and Atarax

The prehistory is as follows: At 2.3 years old, she gave her daughter to the garden - when I left - she was not very capricious, but the teacher later told me that my tail follows her all day, does not play with anyone, and when she loses sight of her - hysteria. At home, the daughter said that the children offended her, etc.

In general, we walk for 3 days - we get sick for 2 weeks. In February (after 4 months of unfortunate walking in the garden) I got into somatics with pneumonia (with all the ensuing procedures - injections, etc.), after which I took it off the garden - to this day we don’t go. A month after the hospital, the child began to stutter sooo much - she could hardly utter anything (this despite the fact that she had already been talking in whole sentences since the age of 1.6). As a result, terrible neuroses began, daily tantrums for a single hour (especially before bedtime). In general, the child was changed.

The neurologist prescribed Phenibut. They drank the course - speech was completely restored, and tantrums after discontinuation of the drug began with new force(as I found out later, it had to be canceled gradually).

In view of this, the doctor prescribed Atarax, but after reading the annotation and reviews of those who took it, my hair stood on end and I was afraid to give it. As I understand it, this is a fairly strong medicine, and if we “got down” with phenibut with wild tantrums, then what will happen after Atarax. Or am I wrong? Maybe I misunderstand how it works.

In general, neuroses obsessive movements periodically appear and gain momentum. Are we really going to be on medication all our lives, or will it go away with age.

Maybe someone faced this problem, tell me?

Well, about Atarax, of course, if anyone took it - what was the result?

Atarax

The description is current as of 04/14/2014

• Latin name: Atarax
• ATX code: N05BB01
• Active ingredient: Hydroxyzine hydrochloride
• Manufacturer: UCB Pharma, S.A. (Belgium)

Compound

Atarax contains hydroxyzine hydrochloride ( active substance) and microcrystalline cellulose, lactose monohydrate, magnesium stearate, colloidal silicon anhydride, macrogol, titanium dioxide, hydroxypropyl methylcellulose.

Release form

Produced in the form of oblong tablets with a white shell. They have

dividing transverse risk on both sides. Tablets of 25 mg are packaged in blisters of 25 pieces, sold in cardboard packs.

pharmachologic effect

The main active ingredient of the drug Atarax - hydroxyzine dihydrochloride is a derivative of diphenylmethane. The drug is not a CNS depressant, but it can have a depressing effect on the activity of some areas of the subcortical region.

Atarax has a bronchodilatory and antihistamine effect on the body. If taken in therapeutic dose, there is no effect on the secretory and acid-forming functions.

It has an effective effect in the treatment of pruritus, allergic dermatitis, eczema, urticaria. If the patient has impaired liver function, the duration of the antihistamine action increases to 96 hours.

There is a sympatholytic, antispasmodic, mild analgesic effect. After taking the drug, patients report an increase total duration sleep period, a decrease in awakenings at night and their period, a decrease in muscle tone. In this case, no memory impairment occurs.

Pharmacodynamics and pharmacokinetics

The drug Atarax is absorbed in the gastrointestinal tract and quickly enters the bloodstream. The highest plasma concentration is observed 2 hours after taking the tablets. Bioavailability after oral administration is 80%. The active substance hydroxyzine is distributed throughout the body and mainly accumulates in the tissues.

Hydroxyzine can pass through the placental and blood-brain barrier. As a result, it accumulates in the tissues of the fetus in high concentration. Metabolites also pass into breast milk.

During the metabolism of hydroxyzine, cetarizine is predominantly formed, which has the properties of a histamine receptor antagonist.

Metabolites of the drug are excreted from the body unchanged in the urine.

It should be borne in mind that in the elderly, as well as in those who suffer from impaired liver and kidney function, an increased concentration of metabolites in the blood is noted during drug treatment. Therefore, in order not to appear side effects need to lower the dose. How many tablets can be taken, in this case, the attending physician should determine.

Indications for use

Atarax tablets are prescribed for the treatment of adult patients in the following cases:

• In order to eliminate the manifestations of anxiety, internal stress, psychomotor agitation, high irritability in the treatment of patients with neurological, somatic, mental diseases.
• In chronic alcoholism, as well as to eliminate the withdrawal syndrome, which is accompanied by psychomotor agitation.
• As a somatic agent during premedication.
• How symptomatic remedy to eliminate skin itching.

Indications for the use of Atarax are determined by the attending physician. As a rule, indications for the use of the drug are available for a variety of skin diseases accompanied by severe itching.

Contraindications

Atarax should not be taken if a person has the following diseases or states:

Due to the fact that the product contains lactose, Atarax should not be taken by those who have hereditary galactose intolerance, malabsorption of glucose and galactose.

Side effects

Atarax can provoke the manifestation of side effects due to the effect of the drug on the central nervous system. In particular, sometimes it causes depression of functions, paradoxical stimulation, and has an antichodinal effect.

• Functions of cardio-vascular system: blood pressure rarely decreases, heart rate increases.
• Functions of vision: decreased clarity of vision, disturbance of accommodation.
• Functions of the gastrointestinal tract: a feeling of dry mouth, rarely - vomiting, nausea, problems with intestinal motility and, as a result, constipation.
• Functions immune system: hypersensitivity, anaphylactic shock can rarely develop.
• Functions of the urinary system: urinary retention is rarely possible.
• Respiratory functions: rarely - bronchospasm and suffocation.
• Neurological disorders: drowsiness, headache, insomnia, dizziness, rarely - convulsions.
• Mental disorders are rare: agitation, disorientation, hallucinations are possible.
• Skin: itching, rash, rarely - swelling.
• General disorders: weakness, fever, fatigue.

Application instruction of Atarax (Way and dosage)

Instructions for Atarax should be strictly observed during treatment with the drug. The medicine is taken orally. In the treatment of anxiety, it is recommended to use 0.05 tablets daily. If the patient has a severe degree of anxiety, 0.3 g of the drug can be taken per day.

If itching is being treated, then initially the patient is recommended to use 0.025 g of the drug. If necessary, this dose of Atarax can be taken 3-4 times a day. The most large dose taken at the same time, should not exceed 0.2 g, and the dose per day should not exceed 0.3 g.

In the treatment of itching in children preschool age(from 3 years old) used daily dose 0.001-0.0025 g/kg of the child's weight.

Wikipedia shows that the dose is most often selected individually. It depends, first of all, on how the body reacts to treatment.

Overdose

In case of an overdose of the drug, the following phenomena can be observed:

• increased anticholinergic effects;
• paradoxical stimulation or depression of the central nervous system;
• manifestations of involuntary motor activity;
• nausea, vomiting;
• impaired consciousness and hallucinations;
• arterial hypotension, arrhythmia;
• in rare cases with a strong overdose - convulsions, tremors, disorientation.

When taken too a large number the drug is important to induce vomiting, rinse the stomach. Measures are taken to support vital functions organism. The patient is monitored until all symptoms of intoxication disappear.

Interaction

The effect of the drug on the body is enhanced if it is taken simultaneously with drugs that suppress the function of the central nervous system. If there is a need to take such drugs at the same time, then the doctor conducts the selection of doses on an individual basis.

Atarax and drugs that belong to the group of MAO inhibitors and anticholinergics should not be taken simultaneously.

If you take Cimetidine and Atarax at the same time, the concentration of hydroxyzine in plasma increases, the concentration of metabolites decreases.

Atarax disrupts the metabolism of substrate preparations for uridine diphosphate and glucuronyl transferase.

When taking Atarax, the effect of drugs that depress the central nervous system is potentiated: barbiturates, opioid analgesics, tranquilizers, hypnotics, ethanol.

Terms of sale

It can be purchased at pharmacies with a doctor's prescription.

Storage conditions

It is necessary to store Atarax in a dark and dry place where the temperature is not more than 25 degrees Celsius.

Best before date

You can store the drug for 5 years.

special instructions

If the patient needs to undergo allergic tests, treatment with the drug is stopped five days before the study.

Patients who drive a car should take into account that the drug may affect the speed of reaction and concentration.

If the patient has a history of convulsions, then treatment with the drug should be carried out very carefully.

Given the fact that Atarax has an anticholinergic effect, it should be carefully used to treat patients with glaucoma, constipation, myasthenia gravis, and dementia. Should refrain from taking sedatives during treatment with this drug.

Carefully prescribe the drug to patients with cardiac arrhythmia, those who use antiarrhythmic drugs. In the treatment of the elderly, half the dose of the drug is initially prescribed.

Analogues

AT pharmacy network you can buy analogues of this drug. One of the analogues of the drug is Hydroxyzine. The price of this drug is lower (about 260 rubles for a pack of 25 tablets). Other analogues of the drug do not have a completely similar composition.

Which is better: Phenibut or Atarax?

Phenibut is a drug that has antihypoxic and nootropic effects. This drug effectively relieves anxiety, tension, normalizes sleep. The cost of a package of Phenibut (20 pcs.) Is approximately 160 rubles. However, this drug is not complete analogue, since the active substance of Phenibut is aminophenylbutyric acid. Therefore, only a doctor can decide to replace one drug with another.

Synonyms

children

The medicine is used to treat children from one year old, but it is necessary to strictly adhere to the indicated dosage and use Atarax only after a doctor's prescription.

With alcohol

Alcohol and Atarax cannot be combined, since the use of alcohol enhances the effect of the drug. The use of Atarax with alcohol causes a significant inhibition of the functions of the central nervous system. Such a combination can increase the state of intoxication, reduce blood pressure, cause allergic reactions.

During pregnancy and lactation

Atarax should not be used for the treatment of pregnant women, as well as during labor. The drug crosses the placenta and enters the fetus directly. During childbirth, the drug can disrupt the course of labor, as it relaxes smooth muscle uterus and prevents its contraction. At breastfeeding Atarax passes into the mother's milk, and a child under one year old is not treated with this remedy.

- Drug, which is characterized by a pronounced sedative, antispasmodic, antiemetic, as well as anxiolytic effects. Indications for the use of Atarax: treatment of Parkinson's disease, withdrawal syndrome in alcoholism, elimination increased anxiety, irritability in neurological and somatic ailments. In addition, the drug helps to eliminate itching in case of dermatological diseases. The main component of the drug is hydroxyzine hydrochloride, Atarax does not include other active ingredients. It should be borne in mind that when taking the medicine, it is worth giving up work that requires increased concentration attention. If treatment is ineffective or there are contraindications, it is recommended to replace the drug or use it with other drugs, so it is very important to assess the compatibility of Atarax with other groups of drugs and take into account contraindications and possible side effects of the drug.

Which is better: Atarax or

Adaptol is one of the tranquilizers, used for symptomatic therapy, helps to normalize sleep, relieves cardialgia, increases the tolerance of neuroleptics, as well as a number of tranquilizers. Thanks to the use of this drug, it is possible to cure neuroses and get rid of nicotine addiction. Although the drugs differ in active ingredients (Adaptol contains mebicar) and differ in the list of indications for use, their specifics are similar. It should be borne in mind that the concentration of metabolites while taking Atarax and cimetidine decreases, as for the interaction with Adaptol, a decrease in the clearance of sertraline is recorded. Medications can be taken both before and after meals, food does not affect the degree of absorption and activity of the active ingredients. When choosing a particular drug, it is worth considering general state patient and clinical picture ailment. It is quite difficult to determine which drug is better, you need to consult a specialist.

Which is better: Atarax or

Phenibut is a drug from the group of nootropics, has psychostimulating effect. It is used for memory disorders, during the period of abstinence with alcohol addiction. Taking the medicine helps to eliminate anxiety, sleep disturbance and stuttering. Therapeutic action manifested through the manifestation specific properties the main component is aminophenylbutyric acid.

Atarax or Phenibut: what works better

If you evaluate the indications for the use of each of the drugs, you can identify matches, but the list of contraindications is significantly different. Atarax is not recommended during pregnancy and lactation, porphyria, hypersensitivity to the components. Phenibut should not be used in case of intolerance active substance. It should be noted that when taking Piracetam with Phenibut, it is necessary to control the vegetative and mental functions. If there is a choice: Phenibut or Atarax, they usually recommend taking the first drug, since the list of contraindications is shorter.

If you need to combine medication, you need to adjust the dosage of each of them. Phenibut can be prescribed for use to potentiate the effect of Atarax.

Which is better: Atarax or Grandaxin

The drug Grandaxin is prescribed for the treatment of depressive conditions, stress, alcohol withdrawal syndrome, PMS, neurosis, and cardialgia. Tofisopam is an active ingredient that acts quite quickly, since the highest concentrations in the blood are recorded 2 hours after taking the pills.

Atarax is a milder-acting tranquilizer most commonly used for mild anxiety and depressive disorders. Grandaxin is much stronger in action, it is used for moderate disorders. The indications for taking Grandaxin are more specific; before starting therapy, it will be necessary to assess the patient's condition and establish accurate diagnosis, it is practically not prescribed for monotherapy.

Which is better: Atarax or

Teraligen is an antipsychotic drug used to treat various ailments nervous system, including depression various etiologies, allergic manifestations and neuroses. The active ingredient is alimemazine. Compared with Atarax, Teraligen is characterized by more a wide range action, helps to eliminate any allergic manifestations, and not only pruritus.

The combination of these drugs is not justified, since they are characterized by a similar mechanism of action. Atarax can be replaced by Teraligen, or vice versa, in case of intolerance to the components or in case of allergy to one of the drugs.

Belgian sedative Atarax is used to treat mental or neurological conditions associated with increased irritability, chronic anxiety, sleep disorders, stress.

The active ingredient is hydroxyzine, which performs an anxiolytic, sedative and antiemetic effect.

Indications for the appointment of atarax include neurosis, irritability, emotional stress, anxiety, withdrawal syndrome with alcoholism, organic lesions central nervous system, relief of vomiting, pruritus.

The drug is contraindicated during pregnancy, lactation, prostatitis, closed angle glaucoma. For children, the remedy is prescribed after 1 year, under the strict supervision of a doctor.

The cost of tablets in Russia is 290-360 rubles. There are exact synonyms, the composition of which contains a similar active substance, but there are not many of them. Close substitutes, where the scope is similar to the indications for taking atarax, are also popular.

Analogues Russian production

The table contains prices and descriptions of medicines from a domestic manufacturer, which are characterized as cheap analogues drug atarax.

Ukrainian substitutes

Modern preparations of Ukrainian production will tell you how to replace atarax if there are contraindications to taking it.

The list is below:

• Gidazepam. Anxiolytic tranquilizer used for neurotic or psychopathic disorders, accompanied by anxiety, irritability, suspiciousness, fear, sleep disorders, as well as chronic alcoholism.

  The drug is prohibited for pregnant women, while breastfeeding, in childhood. The average price is 120–220 rubles.

• Valevigran. The cheapest Ukrainian close substitute for atarax based on valerian extract. A sedative drug that effectively copes with increased nervous excitability, insomnia, depressive and anxiety states. The average price is 45–55 rubles.
• On Sleep. Inexpensive pills Based on valerian root, they have a calming effect on the central nervous system, normalize sleep and general emotional condition. The average price is 40-65 rubles.

Belarusian generics

Belarusian generics, as a replacement for a cheap sedative drug, are presented in the table below:

Other foreign analogues

For more complete overview analogues of atarax should consider its import synonyms:

1. Grandaxin. Tranquilizer based on tofisopam. Indications include neuroses, depressive states, post-traumatic stress disorder, premenstrual stress syndrome, climacteric syndrome, secondary neurotic symptoms, alcohol withdrawal.

   Country of origin - Hungary. The average price is 340–920 rubles.

2. notta. homeopathic remedy in the form of drops for oral administration with a pronounced anxiolytic effect. Helps effectively with psycho-emotional stress, sleep disorders, anxiety, tension, fatigue, attention disorders.

   The drug is produced in Austria. The average price is 210–500 rubles.

3. Persen. Capsules with valerian, lemon and peppermint in the composition with a sedative and antispasmodic effect. It is used for increased nervous excitability, irritability, insomnia. Inexpensive imported sedative drug.

   Country of origin - Slovenia, Switzerland. The average price is 195–590 rubles.

Atarax and its close substitutes are drugs that affect the central nervous system. The preparations have adverse reactions and contraindications, so you should carefully read the instructions. Primary appointment sedatives must be agreed with the doctor.

Please note these medicines able to influence the patient's psychomotor skills. During the treatment period, activities should be limited potentially dangerous species activities that require increased concentration and quick reaction.

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Atarax is a tranquilizer with anxiolytic, antiemetic and sedative effects. It blocks the central m-cholinergic receptors and histamine H1 receptors and inhibits the activity of certain subcortical zones.

Does not cause psychological dependence and addiction. The clinical effect occurs within 15-30 minutes after taking the drug inside.

Renders positive influence on cognitive abilities, improves memory and attention. Relaxes skeletal and smooth muscles, has bronchodilating and analgesic effects, moderate inhibitory effect on gastric secretion. Atarax significantly reduces itching in patients with urticaria, eczema and dermatitis.

At long-term use there was no withdrawal syndrome and deterioration of cognitive functions.

The main active ingredient of the drug is hydroxyzine dihydrochloride. Although the drug does not belong to the CNS depressants, it can have a depressing effect on the activity of certain areas of the subcortical region.

Polysomnography in patients with insomnia and anxiety clearly demonstrates an increase in sleep duration, a decrease in the frequency of nocturnal awakenings after a single or repeated pill intake. A decrease in muscle tension in patients with anxiety was noted when taking Atarax at a dose of 50 mg 3 times / day.

Hydroxyzine is rapidly absorbed from the gastrointestinal tract. Cmax is observed 2 hours after taking the product. After a single dose of the product in a single dose of 25 mg or 50 mg in adults, plasma concentrations are 30 ng / ml and 70 ng / ml, respectively. Bioavailability when administered orally and / m administration is 80%.

In babies, the total clearance is 4 times less than in adults, T1 / 2 in babies aged 14 years is 11 hours, in babies aged 1 year - 4 hours. In elderly patients, T1 / 2 is 29 hours, the distribution coefficient is 22.5 l/kg.

Indications for use

What helps Atarax? A drug is prescribed to relieve irritation, tension, as a sedative of the central nervous system, therefore, it is used in the following cases:

• The main symptomatic indicator of application is pruritus. The medicine does not eliminate the cause of the disease (eczema, urticaria, dermatitis), but only blocks its manifestations.
• Withdrawal syndrome with psychomotor agitation (the so-called "withdrawal" when refusing alcohol, drugs, nicotine, etc.).
• anxiety, stress, psychomotor agitation and irritability, with neurological, somatic and mental disorders.
• Tension and anxiety in the preoperative period.
• postpartum depression.

Atarax is an anti-anxiety drug that inhibits the activity of certain areas of the subcortical region. Has antispasmodic and antihistamine action, increases the total duration of sleep.

Instructions for use Atarax and dosage

The drug is taken orally or injected intramuscularly.

For the symptomatic treatment of itching in children:

• at the age of 1 to 6 years, the drug is prescribed in a daily dose of 1-2.5 mg / kg of body weight in several doses;
• over the age of 6 years - at a dose of 1-2 mg / kg / day in several doses.

For premedication in children, the drug is prescribed at a dose of 1 mg/kg of body weight 1 hour before surgery, and additionally in the evening before surgery.

Adults for the symptomatic treatment of anxiety are prescribed at a dose of 25-100 mg / day in divided doses during the day or at night. The average dose is 50 mg / day (12.5 mg in the morning, 12.5 mg in the afternoon and 25 mg at night).

• If necessary, the dose can be increased to 300 mg / day.

For premedication in surgical practice, it is administered intramuscularly at a dose of 50-200 mg (1.5-2.5 mg/kg) 1 hour before the operation, and additionally in the evening before the operation.

For symptomatic treatment of itching, the initial dose is 25 mg, if necessary, the dose can be increased by 4 times (25 mg 4 times / day). Maximum single dose should not exceed 200 mg, the maximum daily dose is not more than 300 mg.

In elderly patients, treatment begins with a half dose. In renal and / or hepatic insufficiency, doses should be reduced.

It should be remembered that the dosage depends on the body's response to the therapy being carried out and is selected individually by the doctor. The duration of treatment is also determined only by the attending physician, the usual duration is four weeks, but depending on the patient's condition and diagnosis, the doctor may change these values.

Contraindications for use

The appointment of Atarax is contraindicated in the following cases:

• hypersensitivity to any of the components of the drug, cetirizine and other piperazine derivatives, aminophylline or ethylenediamine;
• porphyria;
• pregnancy;
• the period of childbirth;
• breastfeeding period.
• hereditary galactose intolerance, malabsorption of glucose-galactose (because the tablets contain lactose).

Carefully:

• myasthenia gravis; prostatic hyperplasia with clinical manifestations, incl. difficulty urinating, constipation;
• increased intraocular pressure;
• dementia;
• tendency to convulsive seizures;
• patients prone to arrhythmias or receiving drugs that can cause arrhythmias;
• patients simultaneously receiving treatment with other drugs that depress the central nervous system, or anticholinergics (the dose should be reduced);
• patients with severe and moderate severity kidney failure, as well as with liver failure(dose reduction required);
• elderly patients (the dose is reduced in case of reduced glomerular filtration.

Overdose

A manifestation of an overdose of Atarax may be a pronounced anticholinergic effect, depression or paradoxical stimulation of the central nervous system. Symptoms of a significant overdose may include nausea, vomiting, involuntary motor activity, hallucinations, impaired consciousness, arrhythmia, arterial hypotension.

If there is no spontaneous vomiting, immediate gastric lavage is recommended. Vomiting must be induced by artificial means. General supportive measures are shown, including control of vital important functions organism and monitor observation of the patient until the symptoms of intoxication disappear and in the next 24 hours.

If it is necessary to obtain a vasopressor effect, norepinephrine or metaramenol is prescribed. Epinephrine should not be prescribed. Hemodialysis is not effective. There is no specific antidote.

Side effects

Possible side effects when prescribing Atarax:

• drowsiness,
• weakness,
• dry mouth
• headache,
• dizziness,
• tremor,
• ataxia,
• acute increase in intraocular pressure,
• acute urinary retention,
• tachycardia,
• constipation,
• accommodation disorder,
• lower hell,
• increased sweating,
• increased activity of "liver" transaminases,
• bronchospasm,
• allergic reactions.

Pregnancy and lactation

Atarax has reproductive toxicity, crosses the placental barrier and accumulates in high concentrations in fetal tissues. When taking the drug by the mother during pregnancy, after birth, the child has a decrease blood pressure, movement disorders, clonic convulsions symptoms of CNS depression.

In connection with all of the above, Atarax is contraindicated for use during pregnancy and lactation.

If necessary, the appointment of the drug during lactation, breastfeeding should be stopped.

Interaction with alcohol and other drugs

• With the simultaneous administration of Atarax with drugs that have a suppressive effect on the central nervous system, its effect on the body is enhanced, which must be taken into account when determining the dosage.
• It is not allowed to simultaneously take Atarax with drugs from the group of MAO inhibitors and anticholinergics.
• With the simultaneous administration of the drug with Cimetidine, an increase in plasma hydroxyzine occurs.
• Simultaneous administration is also not recommended. medicines that depress the function of the central nervous system, due to the increase in the effect of their intake.
• It is known that Atarax suspends the anticonvulsant action of phenytoin and the action of adrenaline.
• It was noted that when taking alcoholic beverages the effect of the drug is enhanced.

Analogues and prices Atarax, list of drugs

If necessary, Atarax can be replaced with structural analogue is the drug Hydroxyzine.

The following synonyms and substitutes for Atarax are distinguished:

1. Gidazepam.
2. Phenazepam.
3. Relanium.
4. Grandaxin.
5. diazepam.
6. Diazepex.
7. Zolomax.
8. Stremaza.
9. Vinpotropil.
10. Teraligen.

When choosing analogues, it is important to understand that the instructions for use of Atarax, price and reviews of drugs similar action do not apply. It is important to consult a doctor and not to make an independent replacement of the drug.

In pharmacies in Russia, it is sold strictly according to a doctor's prescription. The price depends on the pharmacy and the form of release, on average they are 272-369 rubles per pack of tablets of 25 mg No. 25.

Which is better - Phenibut or Atarax?

- This is a drug that has an antihypoxic and nootropic effect. This drug effectively relieves anxiety, tension, normalizes sleep. The cost of a package of Phenibut (20 pcs.) Is approximately 160 rubles.

However, this drug is not a complete analogue, since the active ingredient of Phenibut is aminophenylbutyric acid. Therefore, only a doctor can decide to replace one drug with another.