Biseptol application and doses. Where does false information come from? Storage conditions and shelf life

In contact with

Classmates

When is biseptol indicated?

Toxoplasma; streptococci and staphylococci; the simplest microorganisms; toxoplasma; coli; pathogenic fungi.

Contraindications

Side effects

Biseptol - instructions for use, analogues, price, reviews

The drug Biseptol

Biseptol also has an effect on microorganisms that are resistant to other sulfanilamide drugs.

Release forms

120 mg tablets (100 mg sulfamethoxazole and 20 mg trimethoprim);
480 mg tablets (400 mg sulfamethoxazole and 80 mg trimethoprim);
Tablets "Bactrim forte" 960 mg (800 mg of sulfamethoxazole and 160 mg of trimethoprim);
Syrup (or suspension) - for oral administration 100 ml (in 1 ml - 40 mg of sulfamethoxazole and 8 mg of trimethoprim);
Concentrate for solution for injection 480 mg (in 1 ml of concentrate - 80 mg of sulfamethoxazole and 16 mg of trimethoprim).

The drug should be stored in a dry place at a temperature not exceeding +25 o C.

Instructions for use Biseptol

Indications for use

diseases respiratory tract(bronchitis in acute and chronic form; pneumonia; pleural empyema - purulent inflammation membranes of the lungs; abscess or abscess of the lung; bronchiectasis - expansion of the lumen of the bronchi due to the disease);
ENT pathology (otitis media, or inflammation of the ear; sinusitis, or inflammation paranasal sinuses nose);
intestinal infections (dysentery, paratyphoid A and B, cholera, typhoid fever);
infections urinary organs(urethritis - inflammation of the urethra; prostatitis - inflammation of the prostate gland; pyelonephritis - inflammation of the renal pelvis and the kidney tissue itself; salpingitis - inflammation of the uterine appendages);
gonorrhea (venereal disease);
soft tissue and skin infections (pyoderma, or pustular skin lesions; acne; furuncle, or boil);
meningitis (inflammation meninges) and abscess (abscess) of the brain;
septicemia (a form of "infection" of the blood);
infectious diseases: brucellosis, malaria, toxoplasmosis, borreliosis, scarlet fever;
wound infections and osteomyelitis;
prevention and treatment of pneumocystis pneumonia in HIV-infected patients.

Contraindications

with severe cardiovascular insufficiency;
with diseases of the hematopoietic organs;
with liver failure;
with severe renal failure;
during pregnancy;
mothers when breastfeeding;
with deficiency of glucose-6-phosphate dehydrogenase (hereditary disease);
children under the age of 3 months and premature babies;
at elevated level bilirubin in children;
with hypersensitivity to the components that make up the drug, or to other sulfanilamide drugs.

With caution, Biseptol can be used if the patient has previously been allergic to other drugs; with bronchial asthma; patients with folic acid deficiency; with diseases of the thyroid gland; in early childhood and old age.

Side effects

From the digestive system: in rare cases - diarrhea, abdominal pain, loss of appetite, nausea, vomiting; in isolated cases - colitis (inflammation of the intestine); reactive inflammation of the liver with bile stasis - cholestatic hepatitis; glossitis - inflammation of the tongue; stomatitis - inflammation of the oral mucosa; pancreatitis is inflammation of the pancreas.
From the nervous system in some cases: dizziness, headache, depression, fine trembling of the fingers of the extremities.
From the side of the kidneys in rare cases: an increase in the volume of urine, inflammation of the kidneys (nephritis), excretion of blood in the urine.
On the part of the respiratory system: bronchospasm, cough, shortness of breath or feeling short of breath.
On the part of the hematopoietic organs in isolated cases: a decrease in the number of leukocytes in the blood, a decrease in the number of neutrophils (a type of leukocyte that protects the body from infections), a decrease in platelets (platelets involved in blood clotting), folic acid deficiency anemia.
On the part of the skin: rashes on the skin in the form of urticaria; itching; in isolated cases - Lyell's syndrome and Stevens-Johnson syndrome (the most severe variants allergic manifestations on the skin and mucous membranes with necrosis and rejection); Quincke's edema (local or diffuse edema subcutaneous tissue and mucous membranes) hypersensitivity to ultraviolet rays.
There have been isolated cases of chills and fever after taking Biseptol (drug fever).
Pain in joints and muscles.
Thrombophlebitis (at the injection site).
Decreased levels of potassium, sodium, and blood sugar.

Side effects are usually mild and disappear after discontinuation of the drug.

Biseptol treatment

Biseptol should be taken after meals. To prevent complications in the form of the formation of crystals in the urine and urolithiasis it is necessary to drink the medicine with a sufficient amount of water, and for the entire course of treatment to provide plenty of fluids (at least 2 liters per day).

Biseptol should not be taken simultaneously with Aspirin, Butadion, Naproxen.

The dose of the drug and the duration of administration is prescribed by the doctor individually, depending on the severity of the condition and concomitant diseases.

Biseptol for children

Biseptol with angina

Biseptol with cystitis

Biseptol's analogs and synonyms

Asacol (active ingredient: mesalazine);
Dermazin (active ingredient: sulfadiazine);
Ingalipt (active ingredients: streptocide, sodium sulfathiazole);
Ingaflu (active ingredient: streptocide) and other sulfa drugs.

Synonymous medicines are medicines with the same active ingredients, but having different names, because are produced by different companies. These are generic drugs. They may differ in dosage forms, but have the same pharmacological properties.

Reviews about the drug

The price of the drug

Biseptol tablets 120 mg - 20 pieces - 31 rubles.

Biseptol tablets 480 mg - 20 pieces - 67 rubles.

Biseptol in ampoules 480 mg (5 ml) - 10 pieces - 340 rubles.

Biseptol suspension 80 ml (240 mg in 5 ml) - 120 rubles.

What helps Biseptol

Biseptol is a widespread and fairly effective antibacterial agent that helps to cope with the manifestations of many infectious and inflammatory diseases of the body.

This drug is actively used in the treatment of acute or chronic inflammatory diseases of the respiratory, urinary, gastrointestinal and other systems.

The main operating medicinal substance of this antimicrobial drug is sulfamethoxazole, which has a pronounced antibacterial effect against the most common infectious agents(staphylococci, streptococci, gonococci, etc.).

The effectiveness of treatment with Biseptol primarily depends on the severity and severity of the inflammatory disease of the body, while the average course of treatment with this drug is 5-7 days.

The main indications for the use of Biseptol:

acute or chronic inflammatory diseases of the respiratory tract of the body (tonsillitis, tracheitis, bronchitis, pneumonia);
diseases genitourinary system(pyelonephritis, cystitis, prostatitis, urethritis);
infectious and inflammatory diseases of the digestive tract (diarrhea, dysentery, cholera);
otitis media (inflammation of the ear);
gonorrhea;
infectious lesions of the skin of the body (furunculosis, pyoderma);
meningitis (an acute infectious disease that affects the membranes of the brain).

Attention: before using Biseptol, it is necessary to consult with a general practitioner in order to prevent possible development unwanted complications.

A medicinal antibacterial drug is produced in the form of tablets with different amounts of the active drug substance.

How to drink Biseptol?

For adults daily dose Biseptol depends on the specific disease of the body and at the same time is 1-2 tons. 2-3 r. a day after meals, drinking plenty of water.

The minimum interval between taking the drug should be 5-6 hours, while the average course of treatment with Biseptol is 5-7 days. Children from 3 to 6 years old this antibiotic assigned to ½ t. (mg.) 1-2 p. per day strictly according to the prescription of the attending physician.

With enough heavy inflammatory diseases body (acute bronchitis, pneumonia), the drug should be taken for at least 7-10 days, 1 ton (mg.) 2-3 r. a day after meals.

Contraindications to the use of Biseptol

increased individual sensitivity of the body to the main active ingredients of the drug;
acute renal failure;
pregnancy and lactation (breastfeeding);
stomach ulcer and 12 duodenal ulcer;
severe liver disease;
severe inflammatory diseases of cardio-vascular system organism.

Side effects of Biseptol

The most common adverse reactions from long-term use of this antibacterial drug are:

dry mouth;
violation of the digestive system (diarrhea, nausea, flatulence, constipation);
dizziness (very rare);
skin itching;
headache;
loss of appetite;
allergic rash on the body (most often urticaria occurs).

With the development of any of the above side effects, it is recommended to completely stop further use of the drug, and also, be sure to consult a doctor!

In this article, we found out what Biseptol helps from, and also examined how it should be taken correctly.

Biseptol from what diseases

At the end of the 20th century, Biseptol became such a common drug that it was used with and without a prescription for any reason, seeing it as a panacea for many ills. Today, the popularity of the drug began to subside. What is biseptol and what it helps from, few are interested. However, until now, in the memory of people, this far from harmless remedy remains a cheap way to deal with certain diseases. How justified is the "unauthorized" treatment with biseptol?

What is biseptol and is it related to antibiotics?

In the minds of the Russian people, the most dangerous in terms of side effects medicines are antibiotics. In this regard, the question arises: is Biseptol an antibiotic or not? Can it be taken without a prescription?

The medicine belongs to the group of antiseptics, i.e. antibacterial drugs. The active substances in it are:

sulfamethoxazole (suppresses the reproduction and growth of bacteria); trimethoprim (enhances the action of sulfamethoxazole).

Biseptol cannot be attributed to antibiotics, since the latter are substances natural origin, and Biseptol components are created in the laboratory.

Although the drug has nothing to do with antibiotics and belongs to the group of sulfonamides, you should not think that it is absolutely safe. At wrong therapy there is an addiction of microorganisms to the components of this agent. Frequent use makes biseptol ineffective, and the disease becomes chronic.

The medicine is available in several forms:

in tablets of 480 and 120 mg (the last option is for children); in the form of a suspension or syrup (1 tsp suspension (5 ml) contains 240 mg of the active substance; it must be shaken before use); in the form of ampoules of 480 mg for injection in a hospital setting.

When is biseptol indicated?

The spectrum of influence of this representative of sulfonamides is quite wide:

In this regard, the range of diseases in which the doctor can prescribe biseptol will also be wide:

respiratory diseases: tonsillitis, pharyngitis, tonsillitis, bronchitis, sinusitis, tracheitis and others; infectious diseases of the urinary tract; diseases of the gastrointestinal tract (typhoid fever, paratyphoid fever, diarrhea and others).

The desire of many people to use biseptol for the treatment of colds and ARVI is not always advisable, since these diseases are caused by viruses that are not sensitive to antibacterial drugs.

But with angina or complications of a bacterial nature after viral diseases ENT organs and respiratory organs, the use of the drug is fully justified. In these and other cases, the question arises of how to take biseptol and what the dosages will be.

For children from 2 months to 5 years, a suspension is used - 240 mg 2 times a day. If the child can take tablets, then 2 tablets 2 times a day with a dosage of 120 mg are recommended.

Children from 6 years of age can be given 480 mg tablets twice a day. Adolescents from 12 years of age and adults are recommended a dose of 960 mg 2 times a day. Treatment should continue for at least 5 days and no more than 2 weeks. If therapy is completed before the period indicated by the doctor, there is a risk of the survival of the most resistant microorganisms and the acquisition of the disease chronic form.

It is quite natural to prescribe biseptol for cystitis. Most cases of this disease are caused coli. However, you should not try to cure any pain in the genitourinary system with this medicine. Most often, fluoroquinolone drugs are prescribed for cystitis. Unjustified use of Biseptol for cystitis can lead to the survival of some microorganisms, as a result of which the disease becomes chronic.

Biseptol should be given to children only under the supervision of a doctor. Most parents do not even have a clear idea of what biseptol is and what it helps with. If you treat kids with them uncontrollably, you can only do harm. Most early age when you can give Biseptol to children - from 6 weeks.

When taking the medicine, you need to remember the rules:

it is necessary to take the medicine strictly every 12 hours; take the drug after a meal; withstand minimum exchange rate treatment - 5 days.

Contraindications

Biseptol is not prescribed to patients:

with diseases of the liver and kidneys; disorders of the hematopoietic system; during pregnancy and lactation; with individual intolerance to the components of the drug.

Side effects

Among the side effects of biseptol can be noted:

rash, hives, dermatological diseases; diarrhea, nausea, stomatitis, loss of appetite; intestinal dysbacteriosis; candidiasis, thrush.

These side effects are among the most common. In case of their manifestation, it is necessary to immediately stop taking the drug.

Recent studies have noted other adverse reactions, however, they occur once in several thousand people, for example, a violation of the hematopoietic system.

Most often in pharmacies you can find Biseptol, produced by Polish pharmacists. However, there are also less expensive foreign and Russian counterparts:

Seneksi Bactrim (France); Co-trimoxazole (Russia); Bi-septin (Holland); Septrin (England).

Which analogues of biseptol to choose depends on the doctor's recommendations and the patient's financial capabilities. Dutch products are characterized by excellent quality, however Russian drug much cheaper.

Biseptol is by no means a harmless remedy, and you should not use it without consulting a doctor, although it is not an antibiotic. Negligence in treatment can lead to the fact that the medicine does not help, but only harms. You need to be especially careful in relation to children: the side effects of biseptol and improperly selected therapy sometimes provoke hardly remediable consequences.

What helps Biseptol and what is the mechanism of its action

Biseptol actively affects the following microorganisms:

gram-positive and gram-negative bacteria;
protozoa;
staphylococci;
toxoplasma;
streptococci;
mushrooms;
coli.

Indications for use

Some patients believe that since Biseptol is not an antibiotic, it can be taken uncontrollably, but this is not so. The drug has serious side effects, and an increased dose of the drug will not cure prostatitis faster. It is necessary to follow the treatment regimen for inflammation of the prostate and follow all the recommendations of the doctor.

Before you start taking the drug, you must exclude contraindications. Biseptol is not used in the following cases:

pregnancy and lactation;
children's hyperbilirubinemia;
at risk of developing hemolysis.

Taking the drug may be accompanied by the following side effects:

urticaria, rash, erythema;
myalgia, arthralgia.

The tablet form is available in two dosages:
- 120 mg - for children;
- 480 mg - for adults.
Suspension for children with strawberry smell in a bottle of 80 ml. 1 dose - 5 ml contains 240 mg of active substances.
Concentrate for the preparation of a solution for the purpose of infusion. 1 ampoule contains 480 mg of active substances.

Treatment in adolescents and adults:

Treatment in children

How to drink Biseptol in suspension?

The minimum dosage is calculated as follows:

How are Erespal and Biseptol combined when taking?

What helps Biseptol: composition and form of release

To date, the drug Biseptol is known in medicine as an effective antibacterial agent. For little money, it can be purchased at absolutely any pharmacy, and in some cases, the drug can be taken without prior consultation with a doctor.

In addition, the drug is actively used to treat prostatitis in men in combination with other drugs. Let's take a closer look at what Biseptol helps.

The drug contains two main components - sulfamethoxazole and trimethoprim.

The composition of the suspension contains such additional components as sodium salt, lemon acid, water, propylene glycol. The syrup is intended for children, as it tastes sweet.

Ampoules are used to treat patients only in a hospital, they also contain additional substances: sodium, alcohol, ethanol, water.

Tablets are round, light yellow in color. In addition to the main substance, they also include starch, talc, polyvinyl alcohol.

Release form

Biseptol is produced in different dosage forms:

Tablets (120 mg, 480 mg) packed in 20 pieces, each blister contains 10 tablets, so there are 2 blisters in a carton package.
Suspension for internal use(80 ml) is in a brown transparent bottle.
Ampoules for injections (8 ml).

pharmachologic effect

Biseptol is always prescribed in combination with other antibacterial agents. The main active ingredients contained in the preparation actively destroy bacteria. Biseptol differs from other drugs in that it is able to destroy bacteria that do not die from drugs belonging to the class of sulfonamides. The substances contained in the drug disrupt the metabolism in the body of pathogenic bacteria, and also destroy the synthesis of folic acid, as a result of which the microorganisms die. To understand what Biseptol helps from, you need to read the attached instructions.

Pharmacodynamics and pharmacokinetics

The components of the drug are quickly distributed throughout the body, enter the kidneys, lungs, prostate gland, vaginal secret. In addition, substances can cross the placenta to the fetus and enter the mother's breast milk. A large concentration in the body is observed already one hour after ingestion. Biseptol is excreted in the urine ten hours after ingestion.

How to take Biseptol: indications and contraindications

Biseptol is taken when patients have various diseases caused by bacteria. It should be remembered that the drug is considered a second-line antibiotic, and does not affect many harmful microorganisms, is prescribed when pathogenic bacteria are resistant to first-line antibiotics.

The drug actively fights inflammation of the nasal mucosa, namely rhinitis, pharyngitis, laryngitis. In this case, the drug can be prescribed without additional strong-acting agents.

To cure a specific disease, you need to know how to take Biseptol.

The medicine helps to relieve inflammation of the prostate gland in men, alleviate the course of prostatitis, in addition, it destroys the bacteria that have appeared in uterine appendages in women, removes infections from the kidneys, bladder, urethra.

Biseptol affects the bacteria that have settled in the digestive organs, helps to cope with gastritis, pancreatitis, enterocolitis. The antibiotic relieves inflammation formed in the liver, bile with a purulent process.

Biseptol in tablet form is taken for acute infections that have arisen in the digestive tract.

Contraindications

Despite the fact that Biseptol is considered not strong antibiotic, it still can not be used for certain diseases:

With individual intolerance to the components that make up the drug.
With parenchymal pathology of the liver, when the cells of this organ are inhibited.
In acute renal failure, especially when it is not possible to control the condition of the kidneys in the hospital.
With anemia, which is associated with a lack of folic acid in the body.
With violations of the function of the blood and its changes.
During pregnancy and lactation, the active components of the drug lead to the fact that the body begins to suffer from a deficiency of folic acid, namely, it is considered the main one in this period.

Before taking the drug, it is necessary to consult a specialist, since all contraindications must be determined before starting treatment.

Side effects

Taking Biseptol can cause the body to show unwanted reaction, namely:

The digestive system will suffer, namely, vomiting, diarrhea, nausea will appear, the liver and intestines will become inflamed, such a reaction may occur due to the fact that folic acid deficiency is formed in the body.
Work will be disrupted circulatory system, anemia, leukopenia may occur. In addition, the number of platelets in the blood plasma may decrease, which will lead to thrombocytopenia.
There will be a failure in the urinary system, the kidneys, the bladder will become inflamed, a small amount of blood may appear in the urine.
A headache will come, a person will fall into depression, the mood will become depressed, this may be accompanied by frequent dizziness, vasospasm.
An allergy will appear, which manifests itself in the form of a red rash on the skin, while the skin may have itching and burning, urticaria, Quincke's edema. In rare cases, from the use of the drug in patients, anaphylactic shock occurred, which occurred as a result of a gradual decrease in blood pressure.

Such side effects stop immediately after the patient stops taking Biseptol.

Overdose

If the prescribed dose is exceeded medicinal product, poisoning may occur in the form of nausea, vomiting, dizziness, abdominal pain, diarrhea, confusion. With such symptoms, you should immediately stop taking the medicine and call a doctor.

Before medical assistance it is necessary to wash the stomach and start symptomatic treatment. If a person exceeds the normal dose three times or more, chronic overdose may occur, which leads to inhibition of blood cells.

In order to avoid an overdose, you need to know how to take Biseptol and follow the instructions clearly.

Interaction

Biseptol should not be taken simultaneously with drugs belonging to the class of diuretics, most often thiazides, otherwise thrombocytopenia may form.

If you take Biseptol with Phenytoin at the same time, a person may experience a deficiency of folic acid.

Salicylic acid, contained in many drugs, can enhance the effect of this antibiotic.

Simultaneous reception ascorbic acid and those drugs that oxidize the urine can lead to crystalluria.

In the case of simultaneous administration of tetracyclic antidepressants, Biseptol reduces their effect.

The drug inhibits the microflora in the vagina, in the intestines, and can also lead to rupture of contraceptives. If a person takes this drug, he needs to drink probiotics as well.

Biseptol: dosage and instructions for use

Biseptol for prostatitis is taken according to a separate scheme. If the patient is diagnosed with a mild disease, then the course does not exceed 21 days.

In the first few days, the doctor prescribes the maximum allowable dose drug, 6 tablets in two divided doses.

The first three tablets are taken in the morning, the last three at night. This dosage is considered the most correct for acute course diseases. The patient's condition improves already on the third day after the start of treatment.

After completing one course, the man must take a break for a month, after which the tests are again taken and, if the result is unsatisfactory, the course is resumed.

Before taking Biseptol, the dosage should be agreed with a specialist.

The drug in this case acts gently, but effectively. The medicine does not reduce the inflammatory process itself, it kills pathogenic microorganisms, as a result of their death, the inflammation disappears on its own.

The drug solution is injected into a vein. In this form, the drug is prescribed to children from 12 years of age, while a single dose does not exceed 10 ml. The drug is injected into a vein every 12 hours.

Biseptol tablets are taken twice a day after 12 hours. Adults are prescribed the drug 950 mg twice a day.

The suspension is taken by adults at a dosage of 950 mg per day. In severe form of the disease, the dosage increases to 1430 mg.

Pneumonia is treated with Biseptol, the dosage of which is calculated depending on the patient's body weight, 100 gr. per 1 kg of weight.

If an infection is found in the urine, it is necessary to take 2 grams. medication twice a day. The course is set separately for each patient, most often it does not exceed two weeks.

If a child has been diagnosed with urinary tract infection, acute otitis media, in this case, appoint 45 mg of medication per 1 kg of weight. The drug is taken every 12 hours. Children under 12 years of age are prescribed a suspension 2 times a day, it has a sweetish taste and is easier to accept by a child. The usual dosage ranges from 2.5 ml for babies aged 4-6 months and up to 10 ml for children 12 years old.

During pregnancy and lactation

The drug is forbidden to be taken if the woman is in position and breastfeeds the baby.

Terms of sale

You can buy medicine in pharmacies, while a prescription from a doctor is required.

Storage conditions

The drug is stored at 25 degrees.

Best before date

Biseptol can be stored for no more than 5 years.

special instructions

While taking this drug, remember that active substances reduce the strength of contraceptives, in addition, the antibiotic violates the microflora in the vagina and intestines. Treatment should take place while taking probiotics.

Groseptol;
Berlocid;
Bactrim.

“Not a bad drug, but it helps only when the disease is not strong, mainly on initial stage, in difficult situations, a stronger antibiotic is needed.

“Biseptol cured my prostatitis in two doses, though the course was long, and I didn’t take anything else.”

Price where to buy

Biseptol in all forms of release can be purchased at pharmacies.

The average cost of the drug in Russia is:

tablets from 50 to 150 rubles;
ampoules from 140 to 200 rubles;
suspension from 170 to 220 rubles.

Biseptol is mild antibiotic, so it can not be used for every disease. The active components of the drug destroy bacteria, as a result, the inflammation gradually disappears. As a rule, this drug is prescribed in combination with other drugs to achieve the best therapeutic effect. A single medication is allowed in case of small inflammations.

What helps Biseptol and how to take it?

What is biseptol and is it related to antibiotics?

In the minds of Russian people, the most dangerous drugs in terms of side effects are antibiotics. In this regard, the question arises: is Biseptol an antibiotic or not? Can it be taken without a prescription?

The medicine belongs to the group of antiseptics, i.e. antibacterial drugs. The active substances in it are:

sulfamethoxazole (suppresses the reproduction and growth of bacteria);
trimethoprim (enhances the action of sulfamethoxazole).

It is impossible to attribute biseptol to antibiotics, since the latter are substances of natural origin, and the components of biseptol are created in the laboratory.

Although the drug has nothing to do with antibiotics and belongs to the group of sulfonamides, you should not think that it is absolutely safe. With improper therapy, microorganisms become addicted to the components of this remedy. Frequent use makes biseptol ineffective, and the disease becomes chronic.

The medicine is available in several forms:

in tablets of 480 and 120 mg (the last option is for children);
in the form of a suspension or syrup (1 tsp suspension (5 ml) contains 240 mg of the active substance; it must be shaken before use);
in the form of ampoules of 480 mg for injection in a hospital setting.

When is biseptol indicated?

The spectrum of influence of this representative of sulfonamides is quite wide:

gram-positive and gram-negative bacteria;
toxoplasma;
streptococci and staphylococci;
the simplest microorganisms;
toxoplasma;
coli;
pathogenic fungi.

In this regard, the range of diseases in which the doctor can prescribe biseptol will also be wide:

respiratory diseases: tonsillitis, pharyngitis, tonsillitis, bronchitis, sinusitis, tracheitis and others;
infectious diseases of the urinary tract;
diseases of the gastrointestinal tract (typhoid fever, paratyphoid fever, diarrhea and others).

The desire of many people to use biseptol for the treatment of colds and SARS is not always advisable, since these diseases are caused by viruses that are not sensitive to antibacterial drugs.

But with sore throat or bacterial complications after viral diseases of the upper respiratory tract and respiratory organs, the use of the drug is fully justified. In these and other cases, the question arises of how to take biseptol and what the dosages will be.

For children from 2 months to 5 years, a suspension is used - 240 mg 2 times a day. If the child can take tablets, then 2 tablets 2 times a day with a dosage of 120 mg are recommended.

It is quite natural to prescribe biseptol for cystitis. Most cases of this disease are caused by E. coli. However, you should not try to cure any pain in the genitourinary system with this medicine. Most often, fluoroquinolone drugs are prescribed for cystitis. Unjustified use of Biseptol for cystitis can lead to the survival of some microorganisms, as a result of which the disease becomes chronic.

Biseptol should be given to children only under the supervision of a doctor. Most parents do not even have a clear idea of what biseptol is and what it helps with. If you treat kids with them uncontrollably, you can only do harm. The earliest age when Biseptol can be given to children is from 6 weeks.

When taking the medicine, you need to remember the rules:

it is necessary to take the medicine strictly every 12 hours;
take the drug after a meal;
maintain a minimum course of treatment - 5 days.

Contraindications

Biseptol is not prescribed to patients:

with diseases of the liver and kidneys;
disorders of the hematopoietic system;
during pregnancy and lactation;
with individual intolerance to the components of the drug.

Side effects

Among the side effects of biseptol can be noted:

rash, urticaria, dermatological diseases;
diarrhea, nausea, stomatitis, loss of appetite;
intestinal dysbacteriosis;
candidiasis, thrush.

These side effects are among the most common. In case of their manifestation, it is necessary to immediately stop taking the drug.

In the course of recent studies, other adverse reactions have been noted, but they occur once every several thousand people, for example, disruption of the hematopoietic system.

Most often in pharmacies you can find Biseptol, produced by Polish pharmacists. However, there are also less expensive foreign and Russian counterparts:

Seneksi Bactrim (France);
Co-trimoxazole (Russia);
Bi-septin (Holland);
Septrin (England).

Biseptol: instructions for use

Biseptol is a combined antibacterial drug that has a wide spectrum of action and activity against a large number various bacteria that cause infectious diseases. Due to the wide spectrum of action, Biseptol tablets are used for infectious pathology. different localization in the body.

Release form and composition

Biseptol tablets are round and white in color. In the middle of the tablet, a dividing line is applied for convenient breaking it in half if it is necessary to reduce the dosage. In one tablet, the concentration of the active substance co-trimoxazole is 120 mg (sulfamethoxazole - 100 mg and trimethoprim - 20 mg) and 480 mg (sulfamethoxazole - 400 mg and trimethoprim - 80 mg). It also contains excipients, which include:

The tablets are packaged in a blister pack of 20 pieces. One carton box contains one blister pack with tablets and instructions for use.

pharmachologic effect

The active substance of the tablets is co-trimoxazole. It is a combination of 2 compounds - sulfamethoxazole and trimethoprim. These substances have antimicrobial action by inhibiting the synthesis of folic acid in the bacterial cell. Sulfamethoxazole blocks the formation of dihydrofolic acid, and trimethoprim its subsequent transformation into tetrafolic acid. Folic acid is necessary for the normal course of the exchange of nucleotide bases in a bacterial cell, which are part of the genetic material (DNA and RNA). Due to this mechanism, Biseptol tablets at low concentrations have a bacteriostatic effect (inhibit the growth and reproduction of bacteria), and with an increase in concentration - a bactericidal effect (cause death bacterial cells). Co-trimoxazole has activity against a wide range of different types of bacteria:

Gram-negative rods (rod-shaped bacteria that, when stained by Gram, stain in pink color) - Enterobacter cloacae, Enterobacter aerogenes, Haemophilus parainfluenzae, Citrobacter freundii, Citrobacter spp., Klebsiella oxytoca, Klebsiella spp., Yersinia enterocolitica, Yersinia spp., Vibrio cholerae. Also Hafnia alvei, Serratia marcescens, Serratia liquefaciens, Serratia spp., cinetobacter lwoffi, Acinetobacter anitratus, Aeromonas hydrophila.
Gram-positive cocci (spherical bacteria, have purple in a Gram-stained smear) - Staphylococcus aureus(methicillin-sensitive and methicillin-resistant), Staphylococcus spp. (coagulase-negative), Streptococcus pneumoniae (penicillin-sensitive and penicillin-resistant).

Stability (resistance) to the active substance of the drug is possessed by pathogens of specific infectious diseases (tuberculosis, syphilis) - Mycoplasma spp., Mycobacterium tuberculosis, Pseudomonas aeruginosa and Treponema pallidum.

After taking the tablets inside, the active substance is absorbed into the blood from the lumen of the small intestine. Therapeutic concentration in the blood is reached within minutes after taking the tablet, and the active substance is almost completely absorbed from the intestine (bioavailability above 90%). Co-trimoxazole penetrates well into all tissues of the body from the blood, penetrates the blood-brain barrier, and accumulates in brain tissues. At a lower concentration, it accumulates in the body of the fetus during pregnancy (passes through the placental barrier) and breast milk during lactation. Almost half of the active substance is excreted in the urine by the kidneys unchanged. Partially, co-trimoxazole is processed in the liver to intermediate decay products that are excreted in the urine and bile.

Indications for use

The use of Biseptol tablets is indicated for various infectious processes in the body caused by bacteria sensitive to co-trimoxazole, these include:

Upper respiratory tract infections - rhinitis (inflammation of the nasal mucosa), pharyngitis (bacterial process in the pharynx), laryngitis (inflammation of the larynx).
Infections of the lower respiratory tract - tracheitis (inflammation of the trachea), bronchitis (damage to the bronchi), pneumonia (inflammation of the lungs, including those caused by Pneumocystis carinii pneumocystis).
Pathology of ENT organs - sinusitis (inflammation of the mucous membrane of the paranasal sinuses), tonsillitis (infectious process in the tonsils) and otitis media (inflammation of the outer, middle or inner ear).
Infections of the genitourinary system - prostatitis (inflammation of the prostate gland in men), a pathological infectious process in the uterine appendages in women, damage to the kidneys, bladder, ureters and urethra.
Infections of the digestive system and gastrointestinal tract- enterocolitis (inflammation of the small and large intestines), gastritis (bacterial damage to the stomach), pancreatitis (inflammation of the pancreas), infectious-purulent processes in the liver and biliary tract. Biseptol tablets are also used to treat especially dangerous infections with damage to the digestive system, in particular cholera.
Some generalized specific bacterial infections caused by bacteria sensitive to co-trimoxazole - brucellosis, actinomycosis (if it is not caused by true actinomycete fungi).

Biseptol is usually a second-line antibiotic, its use is advisable in case of bacterial resistance to first-line antibiotics. Also, Biseptol tablets can be used to treat osteomyelitis (purulent process in the bones) with confirmation of sensitivity to co-trimoxazole in pathogenic bacteria.

Contraindications for use

Biseptol tablets are contraindicated for use in a number of pathological and physiological conditions organisms, which include:

Individual intolerance or hypersensitivity to co-trimoxazole or excipients of the drug.
Parenchymal liver pathology with severe damage or death of hepatocytes (liver cells).
Renal failure, especially if laboratory monitoring is not available functional state kidneys and the level of co-trimoxazole in the blood.
Anemia (anemia) associated with an insufficient amount of folic acid in the body.
Violations of the functional state of the blood system, accompanied by changes in hematological parameters.
Immunological decrease in the number of platelets in the past, caused by the use of co-trimoxazole.
Pregnancy at any stage of pregnancy and breast-feeding - co-trimoxazole can lead to a deficiency of folic acid, which is necessary for the normal development of the fetus or infant.

Availability possible contraindications is determined before the start of the use of Biseptol tablets.

Dosage and administration

Biseptol tablets are taken orally after meals and washed down with a sufficient amount of liquid. They are taken every 12 hours (2 times a day). The recommended therapeutic dose is different for people of different ages:

Children aged 2 to 6 years - 240 mg 2 times a day.
Children aged 6 to 12 years - 480 mg 2 times a day.
Children over 12 years of age and adults - 960 mg 2 times a day.

Also, the dosages of the drug differ, depending on the type of pathogen and the severity of the infectious process in the body:

In pneumonia, the administered dose is calculated on the basis of 100 mg per 1 kg of body weight.
With gonorrhea (an infection of the urinary and reproductive system caused by gonococcus) - 2 g of the drug 2 times a day.

The duration of the course of the drug is prescribed by the doctor individually. Usually it is 5-14 days.

Side effects

Taking Biseptol tablets can lead to the development negative reactions and side effects from various organs and systems, which include:

Digestive system - nausea, vomiting, loose stools, stagnation of bile in the biliary tract with the development of cholestatic hepatitis (inflammation of the liver), pseudomembranous colitis (specific inflammation of the intestine caused by folic acid deficiency).
The hematopoietic system and blood - anemia (decrease in hemoglobin and red blood cells), leukopenia (decrease in the number of leukocytes in the blood) with neutropenia (decrease in neutrophils). An autoimmune decrease in the number of platelets in the blood (thrombocytopenia) is also possible.
Urinary system - hematuria (the appearance of blood in the urine), nephritis (specific inflammation of the kidneys).
Central nervous system - headache, depression (decreased mood, depression), periodic dizziness.
Allergic reactions - a rash on the skin, itching, urticaria (a characteristic swelling and rash that looks like a nettle burn) may develop, angioedema Quincke (pronounced swelling of the skin and subcutaneous tissue with predominant localization in the face and external genitalia). A severe allergic reaction is characterized by the development anaphylactic shock(multiple organ failure with a progressive decrease in systemic arterial pressure).

If signs and symptoms of side effects develop, the drug should be discontinued and seek medical advice. medical care. Side effects are reversible and disappear after discontinuation of the drug.

special instructions

Biseptol tablets can only be used after a doctor's appointment, a study and an appropriate diagnosis. Regarding their application, there are several special instructions that you should pay attention to:

The drug is used with caution in patients with bronchial asthma, other types of allergies (provided that it has not developed to the components of the drug), acute or chronic liver or kidney failure, the elderly.
Simultaneous administration of Biseptol tablets with thiazide diuretics (diuretics) increases the risk of developing hypokalemia (decrease in the level of potassium ions in the blood) and bleeding.
It is not advisable to simultaneously use Biseptol with salicylates, rifampicin, cyclosporine, warfarin.
You can not combine Biseptol tablets and alcohol, as there is high risk development of toxic hepatitis.
During the use of the drug, it is necessary to ensure that a sufficient amount of liquid enters the body.
With prolonged use of Biseptol tablets, it is imperative to conduct laboratory monitoring of the functional state of the liver, kidneys and hematological blood counts.
The drug is contraindicated for use in pregnant and lactating women.
Tablets do not have a direct effect on the speed of psychomotor reactions and concentration. However, when using them, there is a risk of developing side effects from the central nervous system, so it is advisable to refrain from driving vehicles or mechanisms while taking them.

In pharmacies, Biseptol tablets are dispensed by prescription. Do not use the drug on your own or on the recommendations of third parties who are not specialists. If you have any questions or doubts about taking the drug, you should consult your doctor.

Overdose

With a significant excess of the recommended therapeutic dose, symptoms develop acute poisoning- nausea, vomiting, abdominal pain, headache, impaired consciousness. In this case, the drug should be stopped and medical attention should be sought. Detoxification therapy includes washing the stomach, intestines and symptomatic therapy. Chronic overdose can lead to inhibition of hematopoiesis with a significant decrease in the number of all blood cells.

Analogues of Biseptol tablets

The active substance co-trimoxazole is part of such drugs that are analogues of Biseptol - Groseptol, Berlocid, Bactrim, Co-trimoxazole.

Terms and conditions of storage

The shelf life of Biseptol tablets from the date of their manufacture is 5 years. It is necessary to store the drug in a dry, inaccessible place with an air temperature not higher than + 25 ° C.

Biseptol price

Biseptol tablets 120mg - from 27 to 37 rubles.

Biseptol tablets 480mg - from 83 to 109 rubles.

Biseptol is a drug with an effective bactericidal effect. It is used in the treatment of a wide range of diseases and only as prescribed by the attending physician. The drug is not an antibiotic, but belongs to the class of sulfonamides. Consists of Biseptol active components, complementing therapeutic effect each other: trimethoprim and sulfamethoxazole.

pharmachologic effect

Biseptol contains 2 main active substances - sulfamethoxazole and trimethoprim, which have an effective bactericidal and bacteriostatic effect.

Sulfamethoxazole disrupts the release of dihydrofolic acid in bacterial cells. Trimethoprim, in turn, prevents the development of dihydrofolic acid into the active form of folic acid, which affects protein metabolism and division of microbial cells.

Biseptol is rapidly absorbed. Its duration is 7 hours. The largest number Biseptol components are concentrated in the lungs and kidneys. The drug is excreted from the body with urine within 24 hours after ingestion.

In the treatment of a runny nose, cough, colds and flu, Biseptol does not help, more precisely, its use is impractical, since in most cases these diseases are provoked by viruses that are resistant to antibacterial drugs. But the use of Biseptol for angina or complications of diseases of the upper respiratory tract, which are bacterial in nature, is fully justified.

The instructions for the use of Biseptol indicate infectious and inflammatory pathologies of the body, provoked by pathogens that are sensitive to the drug. Biseptol helps with the following conditions.

Infectious diseases of the respiratory system:

pneumonia;
acute and chronic bronchitis;
lung abscess;
pleural empyema;
bronchiectasis.

Diseases of the upper respiratory tract and throat diseases developed against the background of respiratory infections:

Infectious and inflammatory diseases of the genitourinary system:

prostatitis;
cystitis;
gonococcal urethritis;
pyelitis;
chronic pyelonephritis;
gonorrhea.

Infectious diseases of the gastrointestinal tract:

Infectious diseases of soft tissues and skin:

Infectious diseases carried by animals and insects:

Severe forms of infectious and inflammatory diseases:

meningitis;
brain abscess;
osteomyelitis;
sepsis;
wound infections.

Biseptol is prescribed for children in cases of antibiotic contraindications. Its most effective use in the treatment of:

sore throats;
sinusitis;
respiratory infections (including inflammation of the lungs and bronchi);
inflammation of the middle ear;
intestinal infections;
infectious lesions of soft tissues;
furunculosis.

Release form

Biseptol is produced in different forms:

Tablets of 120 milligrams for kids.

Packed in blisters of 20 pieces. Contents of 1 tablet: 100 milligrams of sulfamethoxazole, 20 milligrams of trimethoprim and excipients: polyvinyl alcohol, propylene glycol, potato starch, magnesium stearate, aseptin P and M, talc.

Tablets of 480 milligrams for adults.

Packed in a blister of 20 pieces. Contents of 1 tablet: 400 milligrams of sulfamethoxazole, 80 milligrams of trimethoprim, and similar excipients.

Suspension children for oral administration of light cream color with the smell of strawberries.

5 milliliters (teaspoon) of Biseptol suspension contains 200 milligrams of sulfamethoxazole, 40 milligrams of trimethoprim, propylene glycol, maltitol, propyl hydroxybenzoate, citric acid, sodium saccharinate, methyl hydroxybenzoate, sodium salt, Cremophor RH 40, sodium hydrogen phosphate, magnesium aluminum silicate, purified water and strawberry flavour. The drug is packaged in dark glass bottles of 80 milliliters.

Concentrate in ampoules 5 milliliters for the preparation of a solution for infusions (droppers).

1 milliliter of Biseptol contains 80 milligrams of sulfamethoxazole, 16 milligrams of trimethoprim. The preparation of 10 ampoules is packed in a cardboard box.

The course of treatment and dosage of Biseptol is selected by the attending physician individually, depending on general condition health, age and comorbidities of the patient. In case of severe diseases, the doctor has the right to double the dosage of Biseptol.

Babies from 6 months to 5 years old are usually prescribed syrup or suspension. The recommended dose is 5 milliliters of suspension 2 times a day.

Children who can swallow a tablet should take 2 tablets (120 milligrams) twice daily.

Children from the age of 6 are prescribed Biseptol tablets of 480 milligrams twice a day.

For patients over 12 years of age, Biseptol is prescribed at a dosage of 960 milligrams twice a day.

With pneumonia

Biseptol is prescribed at the rate of 100 milligrams of sulfamethoxazole per kilogram of body weight per day. The break between doses should be 6 hours, and the course of treatment - 2 weeks.

For gonorrhea

The drug is taken 2 grams (in terms of sulfamethoxazole) twice a day with an interval of 12 hours.

With cystitis

If the disease is caused by Escherichia coli, then before using Biseptol, you need to pass an analysis for sensitivity to the drug. Assign the drug at a dosage of 2 tablets 2 times a day, a course of 5 to 10 days.

With angina

Biseptol is prescribed in the recommended age dosage for 5-10 days. Although in recent times with angina, Biseptol is prescribed less and less, as studies show that pathogens (streptococci and staphylococci) lose their sensitivity to this drug.

Admission rules

Between doses of the drug should be strictly observed 12-hour interval.
Biseptol should be taken only after meals, as the medicine irritates the walls of the stomach.
The course of therapy should be at least 5 days, otherwise a complication may develop.
For the period of treatment, it is important to exclude protein foods from the diet, it reduces the effectiveness of the drug and complicates its digestibility. Also avoid alcoholic beverages.

Failure to comply with these rules may lead to a decrease in the effectiveness of Biseptol or the manifestation of side effects.

Contraindications

Damaged liver parenchyma and liver failure severe form;
Impaired kidney function and kidney failure;
Violation of hematopoiesis and severe blood diseases (agranulocytosis, aplastic anemia, leukopenia, megaloblastic anemia, B12 deficiency anemia);
Pregnancy and lactation;
Age up to 3 months;
Hyperbilirubinemia;
Jaundice in children;
Lack of glucose-6-phosphate dehydrogenase;
Hypersensitivity to the composition of the drug.

With extreme caution, Biseptol is prescribed for:

thyroid diseases;
bronchial asthma;
hay fever;
atopic dermatitis;
lack of folic acid in the body.

Side effects

According to studies, in most cases, Biseptol is well tolerated. However, after prolonged use of the drug, there is a risk of developing candidiasis and thrush. Against the background of concomitant pathologies and the body's sensitivity to the drug, the following side effects may occur.

Violations of the nervous system:

apathy;
depression;
aseptic meningitis (provoked by bacteria);
severe and prolonged headaches;
dizziness;
tremor (involuntary contractions of the muscles of the trunk or limbs);
inflammation of the peripheral nerve.

Disorders of the functions of the gastrointestinal tract:

diarrhea, abdominal pain;

nausea, vomiting;

pseudomembranous enterocolitis;

gastritis;

pancreatitis;

glossitis (inflammation of the tongue);

hepatitis.

Respiratory system disorders:

inflammatory allergic reaction of lung tissues;
cough;
bronchospasm.

Violations of the functioning of the circulatory system and complications in hematopoiesis:

thrombocytopenia (decreased number of platelets in the blood);
neutropenia (decrease or absence of granulocytes in the blood);
leukopenia (decrease in white blood cells);
megaloblastic anemia.

Problems of the urinary system:

polyuria (increased amount of urine formation);
hematuria (the appearance of blood in the urine);
increased concentration of urea;
crystalluria (the presence of salts in the urine);
disruption of the kidneys.

Painful manifestations of the musculoskeletal system:

muscle pain;
pain in the joints.

Manifestation of allergic reactions:

hives;
rash;
allergic myocarditis;
increased body temperature;
hyperemia of the sclera;
angioedema;
exfoliative dermatitis;
toxic epidermal necrolysis;
photosensitivity;
multiform exudative erythema.

Do not be afraid of an overly impressive list of adverse reactions to Biseptol. They have been noted throughout the time of release and use of the drug, but may occur in only one in several thousand people.

Pathogenic bacteria are present in the surrounding space of a person, and therefore in his body. Immune cells do not allow pathogenic microflora to develop, but when immunity is weakened or other factors, microbes begin to actively multiply in the body, causing various diseases.

Pathogenic microorganisms include bacteria, viruses, and fungi. Since these are different biological objects, the treatment should be prescribed in accordance with the pathogen. The doctor prescribes the medicine that will be effective in the fight against this or that microbe. One of the most commonly prescribed drugs against bacteria is Biseptol. What Biseptol helps from and how to take it, we will consider in the article.

For the treatment of various inflammatory diseases, two types of drugs are prescribed: antibacterial and antimicrobial. The former contain substances that kill bacterial cells, while the latter inhibit protein synthesis in an enemy cell and stop its vital activity.

The active ingredients of Biseptol do not have components that are present in the natural natural environment, and therefore the drug does not belong to the group of antibiotics. In other words, the drug is completely synthetic.

The composition of the medicine:

sulfamethoxazole - the main active ingredient, stops the growth and development of bacteria;
trimetroprin - has an auxiliary effect, prevents the restoration and reproduction of pathogenic microflora.

Co-trimozole is a synonym for sulfonamides. It is part of Trimethoprim, an antibiotic that is widely used to treat diseases of the urinary system.

Pharmachologic effect:

The bacteriostatic property of the drug is achieved by blocking the biosynthesis of folic acid in bacterial cells by the active substances. Folic acid is involved in metabolic processes in which, with the help of nucleic acids microbial protein synthesis occurs. Violation of biochemical reactions in the cell leads to a cessation of reproduction and to its death from the inside.

Biseptol actively affects the following microorganisms:

gram-positive and gram-negative bacteria;
protozoa;
staphylococci;
toxoplasma;
streptococci;
mushrooms;
coli.

The pathogenic microflora that causes syphilis and tuberculosis is resistant to sulfonamides.

Indications for use

Biseptol is indicated for the treatment of infectious diseases caused by microorganisms sensitive to the active substances of the component. Asking the question: “What does Biseptol help from?” It should be understood that you can not self-medicate. It is true to determine whether the drug will be effective or not, only the doctor can after examining the patient.

The medicine helps with inflammatory diseases of the respiratory system: rhinitis, bronchitis, pharyngitis, pneumonia, laryngitis and others.
Bispetol is often prescribed for infectious lesions of the genitourinary system: prostatitis, inflammation of the uterine appendages, pathological processes in the kidneys, bladder, urethra.
The drug is effective for the treatment of the digestive system: inflammation of the pancreas (pancreatitis), inflammatory processes in the small and large intestines (enterocolitis), gastritis.
Biseptol is prescribed for pathologies of ENT organs accompanied by infection: inflammation maxillary sinuses(sinusitis), inflammatory processes occurring in the inner and outer ear (otitis media), purulent inflammation in the tonsils.

Therapeutic effect on prostatitis

Biseptol for prostatitis is one of the most powerful medicines to combat the disease. It is prescribed if the pathology of the prostate gland is infectious. The active ingredients of the drug penetrate deep into the tissues of the prostate, stopping the development of pathogenic bacteria. Reducing the number and activity of bacteria reduces pain, swelling of the prostate, eliminates other symptoms.

Prostatitis should be treated with Biseptol only on the recommendation of a doctor. Self-medication can be useless or even harmful. After the examination, the specialist will calculate the dosage that will be optimal.

It is necessary to take the drug for inflammation in the prostate for at least two weeks. The first few days the doctor prescribes the maximum dosage, which then decreases. The patient feels relief after 2-3 days, but it is important not to interrupt the course of treatment, as bacteria can develop resistance to the drug. This, in turn, can lead to a chronic form of prostatitis that is difficult to treat.

Therapeutic effect on other pathologies

Biseptol is prescribed for many inflammatory diseases of the respiratory system and ENT organs. And, sometimes, people believe that it can be taken for acute respiratory infections, but in this case the drug is useless, since these diseases are caused by viruses. But angina, tonsillitis, sinusitis and other diseases complicated by bacterial microflora, Biseptol treats perfectly.

Biseptol treatment should be treated with caution when it comes to children. Even if in the past the doctor prescribed a drug for the treatment of, for example, tonsillitis, then in case of a repeated illness, in no case should you give the child medicine on your own.

Otherwise, the bacteria will become resistant, and sore throat will appear again and again.

The therapeutic effect of sulfonamides on various organs manifests itself in the same way, since the principle of influencing bacterial cells is the same. But the doctor determines the dosage and course of treatment individually.

Before you start taking the drug, you must exclude contraindications. Biseptol is not used in the following cases:

anemia (low folate levels);
hypersensitivity to active substances;
pregnancy and lactation;
severe renal dysfunction;
children's hyperbilirubinemia;
damage to the liver parenchyma;
at risk of developing hemolysis.

When taking the drug, care should be taken for people suffering from bronchial asthma and pathologies in the thyroid gland.

The drug can negatively affect different body systems: nervous, respiratory, digestive, musculoskeletal, hematopoietic system.

Taking the drug may be accompanied by the following side effects:

dizziness and pain in the head;
depression, apathy and peripheral neuritis;
abdominal pain, nausea, diarrhea, vomiting;
urticaria, rash, erythema;
cough, choking, bronchospasm;
anemia, neutropenia, agranulocytosis, thrombocytopenia;
increased urea concentration, impaired renal function;
myalgia, arthralgia.

How to take Biseptol for children and adults

For ease of use, Biseptol is available in different dosage forms.

Tablet form available in two dosages:
- 120 mg - for children;
- 480 mg - for adults.
Suspension for children with a strawberry scent in a bottle of 80 ml. 1 dose - 5 ml contains 240 mg of active substances.
Concentrate for solution preparation for the purpose of infusion. 1 ampoule contains 480 mg of active substances.

How to take Biseptol and in what dosage forms depends on the disease and age of the patient.

Treatment in adolescents and adults:

The minimum dose for treatment over 14 days is 480 mg every 12 hours. The standard dosage is 960 mg twice a day, in severe infections the dose is increased to 1440 mg every 12 hours.

The course of treatment for respiratory tract infections and ENT organs is ten days.
Treatment of inflammatory diseases of the genitourinary system ranges from fourteen to twenty-one days.
Diseases of the gastrointestinal tract are treated for at least five days.
Therapy of infectious diseases of the genital organs ( chancroid) spend seven to fourteen days.
For treatment acute infections urinary tract in women, "shock" therapy is carried out, in which a single dose is up to 2880 mg.
Pneumonia is treated with 960 mg twice a day. Individual dosage is calculated as 30 mg/kg.
Nocardiosis is treated at a dosage of 2880 mg for at least three months, acute brucellosis - four weeks, typhoid fever - three months.

How to drink Biseptol tablets and suspensions?

Tablets are drunk every 12 hours, so the medication should be taken in the morning and evening. The drug should be taken only after meals, the tablet is washed down large quantity pure water.

You can not drink the medicine on an empty stomach, otherwise it may cause side effects.

Treatment in children

Up to five years, the drug is prescribed in a standard dosage of 240 mg in the morning and evening. From six to twelve years - 480 mg twice a day. The duration of treatment is seven days.

Children from two one month old up to six months, at birth from a mother infected with HIV, the dosage is 120 mg.

For children, Biseptol is most often prescribed for the treatment of intestinal infections, tonsillitis, otitis media, laryngitis and other infectious diseases of the respiratory tract.

The syrup is used from the age of two months, and tablets of 120 mg - from two years.

With an individual dosage, the suspension is calculated based on 36 mg of the drug per 1 kg of weight.

How to drink Biseptol in suspension?

The medicine should be given to the child after meals, it is advisable to observe the time interval between taking the suspension, which is 12 hours. The medicine is drawn with a special measuring syringe through the neck of the vial. Before drawing up the suspension, the bottle must be shaken well so that the liquid is shaken. There are special divisions on the syringe that determine the dosage.

Biseptol suspension has a pleasant berry taste, so children drink it easily. If the child wants to drink the medicine, then you can give him clean water.

It is important to give the child the medicine exactly in the dose prescribed by the doctor; in no case should one show independence in this matter.

The minimum dosage is calculated as follows:

up to six months - 2.5 ml in the morning and evening;
up to the age of three - 2.5-5 ml twice a day;
up to six years of age - 5-10 ml every 12 hours;
up to twelve years - 10 ml every 12 hours.

Prices:

Tablets 120 mg 20 pieces - 30 rubles;
Tablets 480 mg 28 pieces - 90 rubles;
Suspension 240 mg / 80 ml - 120 rubles.

How are Erespal and Biseptol combined when taking?

Biseptol does not combine well with various drugs and alcohol. In inflammatory diseases of an infectious nature, it is prescribed first of all, if the medicine does not help, then the doctor corrects the treatment.

Erespal is prescribed for the treatment of infectious diseases of the upper respiratory tract. The drugs have different pharmachologic effect on the body, therefore, the attending physician will best answer the question of combining the methods of Erespal and Biseptol.

In contact with

If the microbial infection is moderate, therapy can be used instead of antibiotic treatment. sulfa drugs. One of the popular means of this group is Biseptol in the form of tablets.

Biseptol - what kind of medicine?

Biseptol - a means of the sulfonamide group with complex composition. The 480 mg tablets contain 80 mg of trimethoprim (an antibiotic that works only by the bacteriostatic mechanism of action of kasulfanilamide) and 400 mg of sulfamethoxazole (sulfanilamide). The drug is also produced with a dosage of 120, 240 mg.

This pharmacological combination has another name - co-trimoxazole.

The tablets also include additional substances - magnesium stearate, starch, talc, propylene glycol. The drug is very inexpensive - 100 rubles / 28 tablets. There are other dosage forms on the market. This is a suspension (syrup) for children from 3 months, a solution for infusion (used from birth, in a premature baby - from 2 months).

This medicine belongs to the combined antibacterial agents, it can be taken with a whole range of microbial pathologies. Sulfamethoxazole disrupts the formation of the most important acids for bacteria, which are part of bacterial cells. Trimethoprim is an "amplifier" of the action of sulfamethoxazole, not allowing acid molecules to recover. As a result, protein metabolism in microbial cells is disturbed, their division stops. In the form of tablets, Biseptol helps against diseases that are caused by:

The medicine also works great against the simplest - Plasmodium, Toxoplasma, against a number of pathogenic fungi. Treponema, Corynebacter, Leptospira and all viruses do not respond to therapy with this drug, as do Mycobacterium tuberculosis.

Indications of the drug

The drug helps with most microbial diseases caused by bacteria sensitive to it. For adults and children, the medicine is most often prescribed for ENT diseases, respiratory tract damage. Biseptol is recommended for cough, sore throat, otitis, sinusitis. It is also prescribed for pneumonia, tracheitis and bronchitis, in complex therapy - for lung abscess, empyema. The medicine is indicated in the chronic form of bronchitis and even in severe pneumocystis pneumonia in immunocompromised people.

Biseptol is also prescribed for scarlet fever in children.

Infections of the urinary system, genital area are also successfully treated with this remedy. These include:

If diseases of the peritoneal organs are also caused by microbes, Biseptol is prescribed for their acute and chronic course to relieve inflammation. Among them, you can specify typhus, paratyphoid, cholera, diarrhea of unknown origin. With the help of Biseptol, dysentery, salmonellosis (in the form of carriage), gastroenteritis and cholecystitis are treated. They also prescribe a medicine for damage to soft tissues, skin with pyoderma, boils, purulent rash, wounds, abscesses. Tablets are drunk after operations, in complex therapy for malaria and whooping cough.

Contraindications and side effects

The drug is contraindicated during pregnancy, especially in the early stages, during lactation. In the form of tablets, it is not prescribed for children under 3 years of age. Other contraindications:

In patients with a lack of vitamin B9 in the body while taking it, there is a high risk of developing serious anemia. With caution, therapy is carried out for pathologies of the thyroid gland, with asthma.

The drug inhibits the growth of Escherichia coli in the intestine, which disrupts the production of B vitamins.

More often Biseptol is well tolerated, but side effects are still possible. Headaches, neuritis, dizziness may develop, sometimes depressive states, tremors are noted. Some patients have respiratory disorders, bronchospasm. There is also a risk of developing:

In the most severe and rare cases, hepatitis, pulmonary infiltrates, pancreatitis, anemia and blood disorders, nephritis.

Accurate instruction

Drink Biseptol after meals (to avoid damage to the gastrointestinal tract), drinking plenty of water. The dose is set strictly individually, especially for children from 3 years of age. At 3-5 years old, 240 mg twice a day is recommended, from 6 to 12 years old they give 480 mg twice a day. How much and with what frequency to drink the medicine, the doctor decides, and depending on the type of disease:

The course for infections of the bronchi, respiratory system can be 2 weeks, as with other serious diseases. In milder cases, the course lasts 5-10 days. If required, under the supervision of a doctor, the dose is increased by 30-50%, but only for the first 5-7 days. If the course is more than 5 days, it is imperative to take blood tests to prevent the consequences (anemia and others). In the presence of any changes in therapy, folic acid is administered at a dose of 5-10 mg / day.

Analogues, what else should you know?

There are a number of analogues from the group of sulfonamides, but it is strictly forbidden to replace drugs on your own - they can have different effects.

The drug has poor compatibility with alcohol - toxic effect significantly increased on the liver. Allergy sufferers are treated with caution, a trial dose should be carried out in a reduced dosage. It is not necessary to prescribe the remedy unnecessarily to elderly patients and patients with AIDS, they have a much higher risk of developing side effects. With prolonged therapy, even in the absence of changes in the composition of the blood, folic acid must be prescribed, this does not reduce the antimicrobial activity of Biseptol.

Biseptol is combined remedy, which belongs to the group of sulfonamides. This medicine has a broad spectrum of action and helps to cope with microbes, but is not. At the same time, the substance has many side effects and contraindications, therefore only a doctor can prescribe it.

Composition, release form, packaging

As part of tablets for adults, there are 0.4 mg of sulfamethoxazole and 0.08 g of trimethoprim. Tablets for children have a lower dosage - 0.1 g of sulfamethoxazole and 0.02 g of trimethoprim. The drug is produced in tablet form. There are 20 pieces in the package.

Biseptol release forms

Manufacturer

The medicine is produced by the Polish Pabyanitsky Pharmacological Plant.

Indications

The drug is used for therapy infectious pathologies, which are the result of infection by various microorganisms. Indications include the following anomalies:

infectious lesions of the respiratory system - pulmonary, sinusitis, bronchitis, pneumonia;
sinusitis;
or ;
inflammation and abscess of the brain;
infectious lesions of the genitourinary system - urethritis, cystitis, prostatitis, salpingitis;
infection of the digestive system - cholera, paratyphoid, shigellosis;
gonorrhea;
infectious skin lesions - pyoderma,.

Contraindications

Biseptol can not be used in such cases:

complex forms;
pregnancy;
lactation;
diseases of the hematopoietic system;
lack of glucose-6-phosphate dehydrogenase - is hereditary;
age up to 3 months;
premature babies;
serious;
an increase in the content of bilirubin in children;
high sensitivity to ingredients or other sulfonamides.

With great care, use the remedy for other drugs. The same is true for people with asthma or folic acid deficiency. Caution is recommended for thyroid pathologies. Similar recommendations are given by doctors to children and the elderly.

Mechanism of action

The combination of active ingredients allows you to get a bacteriostatic effect and destroy bacterial microorganisms. The tool is effective against various bacteria.

The action of the drug is due to the blocking effect on metabolic processes bacteria. Sulfamethoxazole contributes to the disruption of the synthesis of dihydrofolic acid, and trimethoprim prevents the next stage of metabolism.

With the help of this tool, it is possible to cope with streptococci, pneumococci, staphylococci. It is effective when infected with typhoid and dysentery sticks, as well as infection with Escherichia coli. At the same time, the remedy does not allow to cope with Pseudomonas aeruginosa, the causative agent of tuberculosis, spirochetes.

Instructions for use

The dosage of the drug is selected individually. The product can be taken after a meal with a glass of the right amount liquids. The volume of the substance is selected according to age. So, at 3-5 years old, 240 mg is shown. Children 6-12 years old should take 480 mg. This should be done twice a day.

With inflammation of the lungs, it is necessary to calculate the daily dosage as follows: 100 mg of sulfamethoxazole per kilogram of the patient's weight. Between receptions it is necessary to maintain an interval of 6 hours. Duration of application is 2 weeks.

With the development of gonorrhea, the dosage should be 2 g of sulfamethoxazole twice a day. Between application you need to do a gap of 12 hours.

All patients over 12 years of age should take 960 mg of the drug twice a day. If long-term treatment is planned, the dosage is reduced to 480 mg.

The duration of the use of this tool is 5-14 days. With a complex course of the disease or the presence of a single dose, it can be increased by 30-50%.

With a duration of therapy of more than 5 days or an increase in the dosage of the drug, it is important to keep peripheral blood counts under control. If abnormal changes are observed, folic acid is prescribed. The dosage of the vitamin is 5-10 mg per day.

In people with kidney failure, in which creatinine clearance is 15-30 ml per minute, the usual volume is halved.

How to take Biseptol for certain diseases:

Side effects

Biseptol usually has excellent tolerance. However, sometimes it provokes undesirable consequences:

The digestive organs react to the use of the drug with the appearance of diarrhea, loss of appetite. Some people have. In rare cases, glossitis, stomatitis, develops.
The nervous system can respond to the reception of the drug, depressive states, . Some people have.
On the part of the kidneys, the volume of urine increases or the organ becomes inflamed. Sometimes .
If the respiratory system is affected, there is a risk of suffocation, air deficiency, coughing.
With the defeat of the hematopoietic system, the volume of leukocytes and neutrophils decreases. There is also a risk of a decrease in the number of platelets or the development of anemia, accompanied by a lack of folic acid.
Feelings may arise. In rare cases, syndromes develop or. It can also become a dangerous complication.
High sensitivity to ultraviolet light may develop.
There are isolated examples of chills after the use of the remedy.

Biseptol can also cause discomfort in muscles and joints. There is a risk of thrombophlebitis in the injection area. In addition, the drug may lead to a decrease in the content of potassium, sugar or sodium. However, usually adverse reactions appear very rarely and disappear after discontinuation of the drug.

Overdose

At overconsumption Biseptol has a risk of such side effects:

increased drowsiness;
dizziness;
nausea;
vomit;
loss of appetite;
disturbance of consciousness;
hepatitis;
fever;
hematuria.

To cope with unpleasant symptoms, the drug should be discontinued and gastric lavage. Also, the patient is shown to drink plenty of fluids. His condition must be kept under control.

At chronic intoxication the drug has a risk of leukopenia. Megaloblastic anemia and thrombocytopenia may also occur. Leucovorin helps to eliminate these symptoms. It is taken at 5-15 mg per day.

special instructions

People with a tendency to allergies, the drug is prescribed with great care. With prolonged use of the drug, there is a risk of changes in blood counts. To minimize these threats, folic acid is prescribed in the amount of 3-6 mg per day.

Biseptol - combination drug belonging to the group of sulfonamides. It contains sulfamethoxazole and trimethoprim. The medicine is often prescribed by specialists for the treatment of various diseases provoked by pathogenic microflora.

The action of the drug

The drug is characterized by a wide range of effects against such microorganisms:

The simplest microorganisms;
Gram-positive aerobic bacteria;
Aerobic bacteria;
Gram-positive anaerobes;
Gram-negative aerobic bacteria;
pathogenic fungi.

Biseptol also inhibits E. coli, causing a decrease in the absorption of B vitamins, nicotinic acid, thiamine, riboflavin, in the intestines. The duration of the therapeutic effect is about 7 hours.

The instruction attached to the Biseptol preparation states that the medication does not act on:

Viruses;
Corynebacterium spp.;
Treponema spp.
Pseudomonas aeruginosa;
Mycobacterium tuberculosis;
Leptospira spp.

Biseptol antibiotic or not

Antibiotics are drugs of natural or semi-synthetic origin, endowed with antimicrobial activity. As for Biseptol, this drug is fully synthesized and belongs to sulfonamides. They are called antibacterial chemical drugs.

Antibacterial agents kill bacteria or inhibit their reproduction and growth.

Sulfonamides penetrate the structure of microbes instead of para-aminobenzoic acid, causing disturbances in the metabolism of their vital activity and the growth of bacteria. Performing such work, sulfonamides are not antibiotics. Drugs represent a different group of antimicrobial drugs.

Sulfonamides became the first systemic antimicrobials. They have been used for more than 65 years, thereby raising the risk of addiction of a mass of microbial strains to this group of drugs. It was possible to increase the sensitivity of pathogenic microbes in the development of combined medicines combining these antimicrobials with trimethoprim. These include Co-trimoxazole and other analogues of Biseptol.

It is worth noting that Co-trimoxazole is a drug - the leader in side effects that pose a threat to life. Danish medical academics have found that Biseptol has a negative effect on hematopoiesis, provoking a condition in which Bone marrow ceases to produce leukocytes - granulocytes, that is, contributes to aplastic anemia.

This phenomenon causes severe violation hematopoiesis, in which patients without the necessary qualified assistance die within a few months. This condition (aplastic anemia) causes complete atrophy of the brain, and in terms of the level of danger it occupies a leading position along with blood oncology.

Composition and form of release

The drug Biseptol release form may be as follows:

Suspensions for oral administration 240 mg / 5 ml - 80 ml bottle. 100 ml contains the active substances trimethoprim - 0.8 g, sulfamethoxazole - 4.0 g and auxiliary ingredients. The medicine is dispensed according to a doctor's prescription.
Biseptol tablets contain for adults 0.4 mg of sulfamethoxazole and 0.08 g of trimethoprim. The medication used to treat children has the following dosage - 0.2 g of trimethoprim and 0.1 g of sulfamethoxazole. The package contains 20 tablets.
Concentrates for injections of 480 mg (in 1 ml of the agent - 16 mg of trimethoprim and 80 mg of sulfamethoxazole).

Pharmacokinetics

The mechanism of action of Biseptol is as follows:

Trimethoprim and sulfamethoxazole, when taken, are completely absorbed by the digestive system.
Trimethoprim is rapidly transported into cells, and also instantly penetrates through tissue barriers into the kidneys, lungs, bile, prostate, saliva, cerebrospinal fluid, sputum. The substance is excreted through the kidneys in half the volume consumed unchanged.
Sulfamethoxazole is supplied through the kidneys, with about 30% in the active form.

Biseptol: indications for use

The drug is intended for the treatment of infectious diseases provoked by pathogenic microorganisms. Biseptol is recommended for:

Infectious lesions of the respiratory system (bronchitis or lung abscess, sinusitis, inflammation of the brain and lungs, sinusitis, otitis media, flu or colds, tonsillitis);
Infection of the genitourinary system (prostatitis, urethritis, cystitis, salpingitis);
Nutritional diseases (shigellosis, cholera and paratyphoid);
Skin lesions - furunculosis and pyoderma.

With cystitis or prostatitis, the effectiveness of the drug can be observed when pathologies are provoked by the following pathogenic microorganisms: fungi, cocci, E. coli. In this case, recovery will be quick and efficient.

Biseptol is used to treat the acute and chronic forms of these diseases.

The dosage for the treatment course is selected individually by the attending physician. Self-treatment is fraught with the risk of getting severe complications. inflammatory processes in prostate, leading to various diseases, are provoked by pathogenic microbes, so you need to know which treatment regimen to use in each specific situation.

Biseptol in pathologies of the infectious nature of the origin of the genitourinary system is prescribed to stop the further transition pathological reaction into a chronic form.

In severe cases of illness, antiviral drug add antibacterial agents with a wide spectrum of action. Therapy is carried out for three weeks, after which the patient is recommended to take a month break. Then treatment should be resumed.

Before using Biseptol, the patient should undergo laboratory research on the subject pathogenic flora. According to the results of the tests, the doctor selects the necessary group of drugs.

AIDS is an incurable disease that kills hundreds of thousands of people around the world

Scientists are constantly developing new drug formulas to help alleviate the condition of patients. Antiviral agent Biseptol can be used to treat HIV-infected children.

Long-term studies have shown that this drug helps to reduce the death rate of children by almost 50%. Today, in many African countries, where the disease is most common in children, they are prescribed Biseptol. This is due to its high efficiency and availability.

Contraindications

Biseptol is unacceptable to use:

Patients with hypersensitivity to incoming components;
Pregnant women;
During lactation;
Children under 6 years of age for intramuscular injection;
Under the age of 3 months;
With pneumocystis pneumonia;
In case of hyperbilirubinemia in children;
With bronchial asthma;
If severe kidney failure is diagnosed;
With a deficiency of folic acid;
When a violation of the functions of the thyroid gland is detected;
With pathologies of the hematopoietic system.

Biseptol can have side effects on the body from:

The drug can provoke an allergic reaction and manifest itself in the form of itching, rash, drug fever, urticaria, fever, exfoliative dermatitis, scleral hyperemia, allergic myocarditis, angioedema.

Summary of dosage and methods of administration

Tablets for internal reception it is recommended to use adult patients and children over 12 years old at 960 mg at a time. However, the drug is allowed to be used at 480 mg twice a day. With the advanced form of the disease, the drug may be prescribed three times a day for 480 mg.

For children 1-2 years old, Biseptol tablets are prescribed at a dosage of 120 mg in the morning and evening, for babies 2-6 years old, the dosage can be increased to 240 mg.

Suspension should be consumed after a meal, drinking a sufficient amount of liquid 960 mg every 12 hours. In severe cases, the dosage of the suspension can also be increased to 1440 mg, which must be taken every 12 hours.

Biseptol in the form of syrup is intended for babies. Up to 2 years, it is recommended 120 mg, 2-6 years 240 mg, in the older category of persons, the dosage is 240-480 mg. You need to drink the medicine twice a day. The duration of treatment depends on the degree of neglect of the inflammatory process and can range from several days to several months.

The drug can be used to prevent recurrence chronic infections urinary tract pathologies. In this case, the recommended dosage is 480 mg once at bedtime. The duration of the therapeutic course is 3-12 months.

In the treatment of acute cystitis in adolescents and toddlers, a regimen of 480 mg twice a day for three days is used. Biseptol for intravenous injections adult category persons and adolescents, 960-1920 mg every 12 hours, children - according to age and existing standards.

For severe infections, use intravenous or intramuscular injection drug. Do not administer the drug concentrate with other solutions. Children over 12 years of age, as well as adult patients, are prescribed injections of 10 ml twice a day. At the age of a child under 5 years, the dosage of the drug is reduced by four times, and for schoolchildren - by half. In severe situations, a half dose increase is allowed for any age group. The medicine must be administered for at least 5 days (when the characteristic manifestations of the disease disappear, and then a couple more days).

Overdose

Failure to follow the doctor's recommendations for the correct use of the drug threatens negative consequences. The substance co-trimoxazole can be life-threatening. In the presence of unpleasant symptoms it is necessary to stop taking this drug and do a gastric lavage, and it is recommended to do this procedure no later than 2 hours after taking the drug. Drinking plenty of water and artificial vomiting will help improve the condition after poisoning.

At chronic poisoning Biseptol may cause a risk of leukopenia. Thrombocytopenia and megaloblastic anemia may occur. Leucovorin, recommended for use at a dosage of 5-15 mg per day, helps to stop unpleasant discomfort.

The state after poisoning should be kept under control.

If any deviations occur, you should immediately contact your doctor and notify him of the problems.

special instructions

When a rash or diarrhea appears on the skin acute stage you should immediately stop taking Biseptol. It is forbidden to take the drug for streptococcal angina.

During treatment with these drugs, patients are advised to drink plenty of fluids.

With prolonged drug therapy, it is necessary to control the parameters of the state of the circulatory system.

It is undesirable to include green vegetables, as well as tomatoes and carrots in the diet. It is forbidden for a long time be in direct sunlight. Biseptol is not recommended for use in pathologies of the respiratory tract. Trimethoprim contributes to a change in the value of the serum residence time of methotrexate.

Biseptol during pregnancy

It is recommended to use the drug for pregnant women only if there is a clear positive result. In the third trimester of pregnancy, it is contraindicated to use it, since Botkin's disease can be provoked in a child. It is desirable to take Biseptol only in liquid form.

During the therapeutic course, pregnant women are prescribed this substance at a dose of 5 mg per day due to a deficiency of folic acid in their body. For nursing mothers with any pathologies, the use of this drug is strictly prohibited.

Alcohol compatibility

Biseptol, like many other drugs, cannot be combined with alcohol and with the protein contained in food. If you drink alcohol and this drug at the same time, you may experience cramps in the limbs. In such cases, an increase in pressure, body temperature is recorded, a suffocating cough is noted.

Biseptol with alcohol can cause an allergic reaction. It may continue to occur every time you use this drug, whether alcohol has been consumed or not. by the most unpleasant moment in tandem of alcohol and the drug becomes cerebral ischemia, which can cause death.

Analogues

Biseptol is produced by various pharmacological companies under the following names:

Bel-septol;
Baktiseptol;
Bebitrim;
Bi-sept;
Raseptol;
Bikotrim;
Triseptol.

Its popular analogues in the form of a suspension and tablets for children have become products made in Poland. A good substitute for this medication is a drug manufactured by the French company Seneksi Bactrim.

The drug Co-Trimoxazole in a dosage of 240 mg and 480 is produced by Pharmstandard. This medicine is inexpensive analogue Biseptol. There are other manufacturers that produce the drug under this name. All of them are united by affordability. In pharmacies, you can also buy more expensive analogues - Bi-septin from Holland, Septrin from the English company Glaxo.

The price of the drug

The price range for Biseptol in domestic pharmacies is as follows:

In tablets 120 mg - 31 rubles. (20 pieces);
In tablets 480 mg - 67 rubles. (20 pieces);
In ampoules of 5 ml - 340 rubles. (10 pieces.);
Suspension 240 mg - 120 rubles.

120 mg per day or 2 tablets of 240 mg after meals with plenty of liquid. In especially severe cases, 6 tablets per day are prescribed. Reception should be divided into two parts - in the morning and in the evening. Therapy, as a rule, is no more than 5 days. With long-term treatment, 2 tablets of 120 mg per day are taken.

For children, the drug is prescribed in the form of a suspension, twice a day. Each suspension bottle has a measuring cap with divisions of 2.5, 5 and 7.5 ml. For aged less than a year, 2.5 ml of medication is prescribed every 12 hours. If the child is between 1 and 3 years of age, 5 ml is usually given twice a day. From the age of 4, you can take 10 ml of the drug, depending on the intensity of the course of the disease and the recommendations of the pediatrician.

Biseptol has a number of side effects that can occur with an overdose or improper use: muscle spasms of the respiratory system, digestive disorders, diarrhea, jaundice, inflammation of the mucous membranes of the mouth. It is also possible deterioration of kidney function and the appearance of allergic reactions. Before taking the drug, you should consult with your doctor and pass the necessary tests. The medication is taken under the supervision of a specialist.

note

Do not use biseptol with intolerance to sulfonamides, which are part of the tablets. It is also recommended to be carefully treated with medicine if there are problems in the functioning of the kidneys and liver. Patients with kidney disease are prescribed a dose depending on current creatinine levels.

Biseptol is a broad-spectrum antimicrobial agent. This drug provides inhibition of pathogenic microorganisms that cause the disease, has a bactericidal effect. You can take "Biseptol" in the form of tablets, suspensions and infusion solutions.

Instruction

The drug "Biseptol" is prescribed for a number of diseases of an infectious and inflammatory nature. This remedy is used in the treatment of respiratory tract infections, in particular, "Biseptol" is indicated in the treatment of bronchitis, pneumonia, as well as pleural empyema and lung abscesses. The drug is used in the treatment of infectious diseases of the genitourinary system: urethritis, prostatitis, pyelonephritis, salpingitis, gonorrhea. Also, "Biseptol" is used in the treatment of dysentery, diarrhea, cholera, typhoid fever and paratyphoid. The drug is effective for infectious lesions skin and tissues, including it is prescribed for furunculosis and purulent formations. Also, "Biseptol" is used to treat sinusitis, otitis and meningitis.

Tablets "Biseptol" should be drunk after meals, 2 times a day. Children 2-5 years old are prescribed 240 mg, 5-12 years old - 480 mg per dose. Children from 12 years of age and adults use a dosage of 960 mg. With long-term treatment, the amount of the drug must be reduced to 480 mg, taking the drug also twice a day. The duration of therapy depends on the complexity of the disease and is 5-14 days. In the treatment of chronic infections and severe disease, a single dose can be increased by 30-50%. In the treatment of pneumonia, the drug is taken at the rate of 100 mg of sulfamethoxazole per kg of the patient's weight per day. The drug should be drunk for 2 weeks, the interval between doses should be 6 hours. For gonorrhea, 2 g of sulfamethoxazole is indicated 2 times a day at intervals of 12 hours.

Suspension "Biseptol" is indicated for adults and children from 3 months. The drug is taken every 12 hours. Babies 3-6 months old are given 2.5 ml each, 7 months - 3 years old - 2.5-5 ml each. Children 4-6 years old are prescribed 5-10 ml, 7-12 years old - 10 ml of suspension. Adults and adolescents should drink the medicine 20 ml at a time. Treatment should be carried out within 1.5-2 weeks, with dysentery - 5 days. Shake the vial with the suspension well before use.

Biseptol solution is administered intravenously. For and children from 12 years of age, a single dosage is 10 ml of the drug. Before administration, the drug should be diluted in 250 ml of dextrose or sodium chloride solution. Intravenous "Biseptol" is used every 12 hours for 5 days. With particularly severe symptoms, the dosage can be increased to 3 ampoules with a frequency of administration 2-3 times a day. The pediatric daily dose of sulfamethoxazole is 30 mg/kg body weight. This amount of medicine should be used for 2 times. Infusion should be done no longer than 1.5 hours.