Ciprofloxacin is an antibiotic. Damage to the skin and soft tissues. For the treatment of prostatitis

Ciprofloxacin is a modern antibiotic that is unique in its characteristics and therapeutic properties. The drug is characterized by a fairly wide range of positive therapeutic effects. It belongs to the category of fluoroquinolones.

Among numerous analogues Ciprofloxacin stands out for its bright antimicrobial therapeutic activity. The general mechanism of influence of this medication lies in the following factors - the antibiotic effectively disrupts the general process of division of natural DNA in numerous bacteria that have entered the body, and their synthesis.

Such a process causes serious changes of a special morphological plan and quickly destroys numerous bacteria.

Ciprofloxacin has been used in medicine for a huge number of years. The drug was developed and released by the well-known organization Bayer in 1983. After about 4 years of basic testing, ciprofloxacin was fully approved for standard use. The drug is used in the form of conventional tablets, other forms of release are used, the choice depends on the established health problems.

Main pharmacological action

Ciprofloxacin 500 mg is a drug with a special bactericidal action, which belongs to the category of modern fluoroquinolones. The drug has a rather active effect on actively developing organisms, as well as on those that are in a state of complete rest and do not manifest themselves for a certain time and are not characterized by the presence of factors provoking certain diseases.

Medicinal substances are very quickly absorbed into the digestive tract, even after a fairly dense meal. The volume of food has no effect on the rate of absorption of basic substances in the tissue and their penetration into the blood.

The main substance is able to penetrate into the cerebrospinal fluid, which is important for a person. The penetration process is not affected by the degree of development of inflammatory pathology. With an average degree of the inflammatory process, the substance remains in the blood in an amount of 10%, but if the inflammation is severe, the concentration level can reach 37%.

In addition, an increased concentration of the substance can be observed in the composition of bile. As for the excretion of the antibiotic, this process is carried out simultaneously with bile and urine.

Popular Applications

Ciprofloxacin is used for a wide variety of diseases. Very often, an antibiotic is prescribed for a variety of bacterial chronic and acute infections, the main causative agents of which are a variety of microorganisms sensitive to treatment. The drug showed optimal efficiency in the process of combating all forms of staphylococci, legionella, mycoplasma, chlamydia, as well as numerous mycobacteria.

Very often Ciprofloxacin in any form is prescribed in modern surgery. The drug is effective in recovery in the usual postoperative time period. In addition, the medication in the form of therapeutic injections and standard tablets is used in the process of eliminating skin inflammatory or purulent pathologies. The medicine perfectly copes with the acute form of sepsis.

As a second-line drug, the drug has been used in the field of pulmonology for many years. The group of the second category is the drugs prescribed in situations where the use of other medications did not provide the desired result. Quite often, modern specialists prescribe a medication in the treatment of severe and chronic infectious pathologies, which differ in that they affect the upper and lower respiratory tract.

Ciprofloxacin has shown its effectiveness in the treatment of lung abscess, acute pneumonia and pleurisy. For the treatment of all the diseases listed above, the drug can be used both in the form of tablets and as injections.

Other areas of use

Ciprofloxacin is widely used in the treatment of various ENT diseases. For example, an antibiotic is prescribed in the treatment of acute sinusitis or various inflammatory pathologies in the middle ear area.

Among other pathologies that are quite successfully eliminated by this drug, it can be noted:

• All forms of otitis media in which the drug Ciprofloxacin is used for several months;
• Various diseases of urology. The drug ideally treats a variety of male pathologies, among which cystitis, all forms of prostatitis, chronic and acute pyelonephritis can be noted;
• Specialists in the infectious field prescribe a drug for the effective treatment of problems such as salmonellosis and acute dysentery;
• The drug is successfully used in the treatment of a variety of mixed aerobic and special plan anaerobic infections. In this case, along with the antibiotic, the doctor prescribes Metronizadol, as well as Lincosamide. The reason for this compatibility is based on the fact that some forms of infectious pathogens of a mixed infection plan are characterized by resistance to drugs.

Quite often Ciprofloxacin is used in dentistry. Often, after the complete removal of the affected tooth, a complex inflammatory process begins in a person, the drug quickly copes with it. No less often, the drug is prescribed for resection of the tooth.

The antibiotic has shown its effectiveness in eliminating pain in the development of pathologies such as periodontitis or more dangerous osteomyelitis.

The main drug categories and types of the drug

Due to the fact that Ciprofloxacin has a wide range of general therapeutic applications, the drug is produced in a variety of types and categories. In direct proportion to the disease and the degree of its development, the doctor may prescribe the following types of antibiotic:

1. Standard tablets;
2. injection ampoules;
3. eye and ear drops;
4. Ointments.

The most common and quite effective is the tablet form of the drug. In this form, the drug is easily stored, easily transported and simply consumed. If the drug is used to quickly and effectively treat a variety of intestinal problems, it shows an ideal high effect. The reason is that Ciprofloxacin tablets provide a fairly rapid destruction of the main infectious focus.

Ampoules ideally help in the elimination of diseases that can only be dealt with by injections.

The drug is administered in an average amount of 200 ml and strictly drip.

Medication injections are used for every infection that has taken on a form with complications and is treated much more difficult, unlike the underlying disease.

In drops, the drug is prescribed when the focus of inflammation is located in the auricle or in the eye. This drug is available in the form of a liquid solution, where approximately 0.3% of the main active component is present. The drops are yellowish in color and contain 3 grams of a substance such as ciprofloxacin hydrochloride.

Ciprofloxacin in the form of an ointment is used in the treatment of various eye diseases. As a therapy, a small amount of the composition is placed on the lower eyelid 4-5 times a day. In addition, the drug in this form is prescribed in the treatment of affected areas of the skin surface that were previously affected by a certain viral infection.

Application instructions

The antibiotic treatment regimen and the total daily dosage directly depend on the type of pathology and the level of its severity. For example, in the process of treating infectious pathologies in the urinary tract, tablets of 0.25-0.5 grams are prescribed twice a day.

For more severe diseases, the dosage can be increased to 0.75 grams, which must be applied every half of the day. If the patient for some reason cannot take regular pills, he is prescribed Ciprofloxacin injections. In this case, the positive effect will be achieved more quickly.

An important rule for the use of ampoules is the dilution of a 1% drug in solutions of glucose or sodium chloride.

There are several basic rules for using the tablet form of Ciprofloxacin. Here are the most basic ones:

1. Tablets are taken at any time, eating does not matter. The use of the drug on an empty stomach slightly accelerates the absorption of the main component into the mucous membrane of the digestive organs;
2. The drug in tablets must be washed down with water;
3. The duration of therapy and the dosage level should be selected by the doctor, who will rely on the type of infection, the weight and age of the man and woman, and the state of health. The specialist will definitely take into account the functioning of the kidneys;
4. In most cases, the dosage is 500-750 mg at a time, it can be used twice a day;
5. The maximum dose of the drug should not exceed 1500 mg per day;
6. The total treatment time is very often around 7-14 days, sometimes up to two months.

With regard to the use of injections, the intravenous use of Ciprofloxacin is carried out in a volume of approximately 200-400 mg. The number of doses per day is two, and the total treatment time is on average 7-15 days. If necessary, ciprofloxacin therapy is extended. The drug is administered in the form of a dropper, as well as a jet. The first option is more preferable.

Drops of Ciprofloxacin are instilled into the eyes one or two drops at a time. It is required to direct the solution under the lower part of the eyelid, and the number of procedures is equal to every 2-3 hours. Time intervals can be gradually increased, and the overall course of treatment depends on the problem that you want to eliminate with this drug.

In case of violation of the functioning of the liver or kidneys, the dosage of the drug may be changed. In the process of prescribing the drug, the doctor relies on the indicators of creatinine clearance. This is the rate at which creatinine is completely eliminated from the human body by the kidneys.

Main contraindications

Ciprofloxacin, like all types and categories of modern drugs, is characterized by some contraindications. First of all, it is dangerous for young children and for pregnant women. The reason for this contraindication is that the drug has an effect on bone tissue and has a detrimental effect on the body during the rapid growth of a person, in which his skeletal part is formed.

Despite this, there are some exceptions in medicine. If a child has cystic fibrosis, which is classified as hereditary, the drug may be considered.

This pathology is distinguished by the fact that it disrupts the process of producing a special bronchial secret, on the basis of which the child often suffers from infectious diseases of the respiratory system. Ciprofloxacin in this case has an excellent positive effect, which is not given by other forms of antibiotics. It is for this reason that the use of this medication is a necessity. In this case, the drug is taken strictly under the supervision of a physician.

Possible side effects and effects

In general, Ciprofloxacin belongs to the category of safe drugs. The medicine is distinguished by the absence of a negative effect on healthy cells, and a detrimental effect on viral and infectious elements.

The main feature of the drug is its ability to destroy cells that are present in different bacteria and infections, because the drug in the process of therapy causes different side effects in only 10% of situations.

The most common adverse events include:

• Various forms of indigestion;
• sleep problems;
• migraine headache;
• The appearance of various allergic skin reactions.

In the most rare situations, there is a decrease in leukocytes and lymphocytes in the blood. In the presence of all the factors listed above, the doctor can change the dosage or completely cancel the pills or injections, it all depends directly on the general condition of the body and on the possibility of replacing this drug with its analogues.

Antibiotic analogs

Ciprofloxacin is characterized by high rates of popularity; the drug has been used in the treatment of various pathologies for several years. The reason for this demand is based on the high efficiency of the drug.

Despite this, the remedy, under certain factors, is replaced by one of the modern analogues. The basis for their appointment is the lack of resistance of some bacteria to this drug, as well as the appearance and development of side effects. Pharmacies sell a huge number of analogues of Ciprofloxacin.

Among the most popular are:

1. Cyprosandosis;

Also, the drug has indirect medicinal analogues. These include various forms of antibiotics belonging to the group of modern fluoroquinolones. The main difference between them is based on the degree of sensitivity to various categories of bacteria.

Only the attending physician has the right and opportunity to replace Ciprofloxacin with a drug of a different category.

Popular questions about antibiotic use

The versatility of the drug makes it very popular. On this basis, patients have a large number of questions before using Ciprofloxacin. Here are the most basic ones.

In what cases and how to use the popular ear drops - Ciprofloxacin?

Ciprofloxacin as ear drops is prescribed for otitis media and other pathologies of this organ.

In other words, this is an acute inflammation in a person of the middle or outer auricle. Before using the antibiotic treatment solution, the ear canal must be well and at the same time very carefully cleaned.

Drops must be at a comfortable room or body temperature, which is important to prevent stimulation of the general vestibular apparatus in the body.

You need to bury about 3-4 drops in a sore ear. The number of procedures depends on the complexity of the situation - from 1 to 4 times per day. After instillation, it is imperative to lie down for 10 minutes on the side opposite to the diseased part of the body. It is required to complete a full course of treatment, which is at least a week. It is not necessary to interrupt it even with the onset of a positive result and relief of the condition.

In especially complicated cases, special gauze turundas can be used. Before use, they are moistened in a medicinal solution of the drug Ciprofloxacin. Such a turunda is laid in the ear for at least 40 minutes. In some situations, the specialist may advise not to remove the tampon at night or until the next treatment event.

Can Ciprofloxacin be taken during pregnancy and lactation?

The use of this antibiotic is strictly contraindicated in any month of pregnancy, also during lactation. A feature of this medication is its ability to quickly penetrate the body, into its tissues and organs. At the same time, a special hematoplacental barrier is not a protection against adverse effects on the fetus or on the child's body. Moreover, the drug penetrates into the blood of a developing fetus in a sufficiently high concentration.

Despite the fact that the antibiotic does not have a particular teratogenic, mutagenic and negative embryotoxic effect, it is able to have a negative effect on some tissues of the child. It manifests itself not only in the process of intrauterine development, but also during the growth and development of the child until he reaches adulthood.

Among the main harmful effects of the drug can be identified:

1. The accumulation of the basic substance in the joints has a negative effect on growth, as well as on the differentiation of cartilage in the form of a process of cell specialization;
2. To a certain extent, the drug has the ability to accumulate in the tissues of the skeleton in a special way, and it also has a negative effect on the growth and formation of bones.

The most serious effect on all important fetal tissues occurs during the first trimester of pregnancy. Further, disturbances in the cartilaginous and skeletal bone tissue are less pronounced, but still extremely important because of their unfavorability.

Ciprofloxacin has the ability to penetrate into the body of the fetus not only through the placenta, but also through breast milk enters the body of the baby. In the second case, the penetration concentration is even stronger, that is, a sufficiently significant amount of the antibiotic enters the body.

From what age group is the drug prescribed?

The drug Ciprofloxacin is very rare, with special indications, it is prescribed in childhood, but not earlier than 15 years. The reason for this restriction is indicated above, that is, taking the drug for children is contraindicated due to its effect on cartilaginous articular tissues.

It is officially allowed to take the drug to children after reaching the age of 18, in order to ensure that major changes are avoided. The drug is used very carefully for problems with the central nervous system. The drug can lower the overall seizure threshold and become the basis for the development of seizures.

In any case, Ciprofloxacin should only be prescribed by the attending physician. It takes into account the overall positive impact of antibiotic use, the likely detrimental effect on the development of the child.

The doctor individually considers each situation and, on this basis, determines the standard allowable daily dosage of the drug and the number of days or weeks of treatment. The doctor takes into account the severity of a particular disease, the physical development and age of the child, his health and condition are important.

Is antibiotic compatible with alcohol?

In the process of using Ciprofloxacin, you should not drink alcohol. The reason is that their main component is ethyl alcohol, like the main substance of the drug, it passes through all the tissues of the body and is metabolized in a special way in the liver.

As a result, this organ begins to experience a significant load, which adversely affects its general condition. If a person is diagnosed with liver failure, the drug is not prescribed at all.

The simultaneous use of ciprofloxacin with alcohol can lead to problems in the form of a disulfiram-like reaction. These are such unpleasant phenomena as:

• Nausea;
• Exhausting vomiting;
• Temperature chills;
• Strong headache;
• palpitations or tachycardia;
• Dyspnea;
• Redness on the skin.

Drinking a large dose of alcohol during treatment with Ciprofloxacin can lead to the death of a person!

How long does the drug treatment last?

The total duration of treatment with a drug in any form can be completely different. In most cases, the remedy is taken for 7-10 days. It is during this period of treatment that the main substance of the drug completely stops the growth and development of the infection, as well as the reproduction of various pathogenic bacteria. In addition, the use of the drug neutralizes microbes, causing complete destruction of the cell walls, as well as the membranes of bacteria that have entered the body.

Unlike other modern antibacterial medicines, Ciprofloxacin very slowly becomes resistant to bacteria. It is for this reason that for certain diseases, the medicine can be taken for a rather long period, up to 3-5 weeks. For example, with sufficiently complicated viral infections, the course of treatment with the drug is increased.

The total duration of therapy and the dosage of the drug, the frequency of administration per day must be determined by the doctor. This is the only way to get a significant positive result in the treatment process. The specialist in the process of resolving these issues relies on the severity of the disease, on the age of the patient, on the total weight of the person, as well as on concomitant diseases.

Does the drug help with prostatitis?

Doctors advise taking Ciprofloxacin in the process. This drug is part of a complex therapy aimed at eliminating this particular disease. The antibiotic allows for the minimum amount of time to completely destroy the main source of infection. Immediately after using the drug, the main active ingredient quickly penetrates into the male organ and remains there in a high concentrated volume.

As numerous reviews of professionals and patients show, Ciprofloxacin tablets quickly remove all unpleasant ones, remove the common pathogenic form from the body, which causes the development of prostatitis. To achieve an optimal positive result, it is important at the medical level to test for microflora sensitivity to the main components of Ciprofloxacin.

This can only be done at the laboratory level, where it will be shown whether certain microbes die from exposure to the antibiotic. In especially difficult situations, Ciprofloxacin is prescribed by the attending physician in the form of daily droppers carried out in a hospital.

Release form and storage of the medicinal product

Ciprofloxacin tablets are available in 250 mg and 500 mg. There are 10 pieces in one blister, and there can be one or two blisters in one package. The average cost of a medication fluctuates around 200-250 rubles.

The tablets are coated, which ensures the preservation of the therapeutic effect of the main components, as well as greatly facilitating the process of taking the tablets. The drug, produced in the form of ointments and drops, has a standard transparent appearance.

The injection form is sold in the form of ampoules. Each of them contains the amount of the drug that is required for a single injection. Store the drug in all forms of its release is required at a temperature not exceeding 25 degrees. It must be a place protected from light, and it is also important to keep the medicine out of the reach of children.

Speaking about the conditions for the sale of the drug in pharmacies, it can be noted that you can buy an antibiotic only by prescription. Now this rule applies to all types and categories of antibiotics.

Interaction with drugs

Before using Ciprofloxacin, it is worth studying the features of its interaction with drugs made on the basis of theophylline. Such a combination can lead to an increase in the total amount and concentration of theophylline in the blood. It also increases the time of its excretion from the body and the main substances of the antibiotic. In addition, the elimination time is significantly slowed down with the simultaneous use of Probenecid.

The slowdown in the absorption and absorption of the main therapeutic components of the antibiotic can be caused by Antacids, which contain aluminum hydroxide or its analogue - magnesium. All this leads to a decrease in the level of concentration of the main substance Ciprofloxacin in the composition of urine and in plasma.

It is for this reason that the time interval between these categories of medicines should be 4 hours, no less. It should be noted that Ciprofloxacin is able to cause activation of the action of anticoagulants of a special coumarin series.

The attitude of people to antibiotics is very different due to the specifics of their action, but no one denies that the discovery of the remedy was a real breakthrough in medicine. Preparations of this type effectively fight most infectious diseases and purulent complications. The antibiotic Ciprofloxacin has become one of the most popular anti-inflammatory drugs of its kind. It is widely used by dentists for the treatment of ENT diseases, infectious inflammations of the internal organs of a person.

What is Ciprofloxacin

The action of the antibiotic Ciprofloxacin is based on its ability to inhibit the enzyme bacterial cells (DNA gyrase) with impaired division, DNA synthesis, and the growth of microorganisms. According to the manufacturer, while taking the drug, resistance to other antibiotics that do not belong to the group of gyrase inhibitors is not developed. The drug is effective against infections that caused the following strains:

• staphylococci;
• chlamydia;
• legionella;
• mycoplasmas;
• enterococci;
• mycobacteria.

If a patient has a mixed infection (aerobic and anaerobic), metronidazole or lincosamides are prescribed in addition to the antibiotic ciprofloxacin. This is due to the moderate sensitivity of such pathogens and some resistance to the drug. The following strains have resistance to the drug, which is formed gradually:

• nocardia asteroides;
• ureaplasma urealyticum;
• treponema pallidum;
• streptococcus faecium.

When using the drug, from 20 to 40 percent of the substance binds to plasma proteins. The agent is perfectly distributed in the tissues of the body through biological fluids. Sometimes the concentration of the drug exceeds the plasma. The drug is able to penetrate into the cerebrospinal fluid through the placenta, into breast milk, a lot of the substance accumulates in the bile. In a natural way, up to 40% of the drug is excreted from the body in the first 24 hours by the kidneys, another part along with bile.

Release forms

The antibiotic ciprofloxacin has a wide range of applications, therefore it is available in different forms. Based on the active substance (fluoroquinolone), there is an impressive list of analogues that have the following names: "Tsiprolet", "Tsipraz", "Cipralon", "Microflokos", "Cyproxin", "Tsiprobay", "Ificipro", "Ciprofan", " Ciproflox, etc. Based on the location of the infection, the severity of the following forms of medication can be prescribed:

• ointment;
• drops for eyes and ears;
• coated tablets;
• ampoules for injections;
• solution for infusion.

Tablets

The most popular form of the antibiotic Ciprofloxacin is tablets. This is due to the convenience of storage, transportation and reception of funds. Unlike intramuscular or intravenous injections of the drug, the risk of complications is significantly lower. At the same time, tablets are not inferior in effectiveness to ampoules. It is preferable to use this form of medication for intestinal diseases, which will provide quick access to the treating substance to the site of infection. The shell of the drug is designed to protect gastric juice during absorption.

Drops eye and ear

Another popular form of the antibiotic ciprofloxacin is drops. It is used if the inflammatory or purulent process is in the eye or ears. Drops are produced in the form of a solution with 0.3% of the active substance. The agent has a yellow or yellow-green color, with the presence of ciprofloxacin hydrochloride in the amount of 3 g. The drug is prescribed for the following diseases:

• blepharitis;
• corneal ulcer;
• chronic eye diseases;
• bacterial conjunctivitis;
• complications after ophthalmic surgery.

Solution for infusion

For intravenous injections of the drug, a solution for infusion is used. Outwardly, the remedy looks like a suspension that is prescribed to children for oral use. The solution has a clear, slightly green or yellow tint. The medication is administered to the patient with the help of a dropper for 30 minutes in the amount of 200 mg and 60 minutes - 400 mg. This method of drug administration is used in almost any type of infectious disease.

Ointment

This dosage form of the antibiotic ciprofloxacin is generally used in the treatment of eye diseases. It is applied in small amounts under the lower eyelid several times a day. In case of infectious skin lesions, the agent is applied 1 time to the affected area, 1 g each or in the form of a compression bandage. The duration of the drug is determined by the attending physician, based on the severity of the patient's condition, the extent of the lesion, the rate of tissue regeneration.

Ampoules for injections

For ease of storage of the drug, it is produced in the form of ampoules with a solution that is used for drip infusion or injections. The rate of the drug depends on the disease, for example, 200-400 mg is prescribed for people with damage to bones and joints, urogenital infections, and damage to the upper respiratory tract. If the intra-abdominal region, respiratory tract, soft tissues of the skin are affected, a single dose is 400 mg.

Instructions for use

Infectious bacteria can infect almost any human organ. Due to this feature, antibiotic drugs are used in all areas of medicine by doctors of various specializations. Depending on the affected area and the localization of the infection, only the dosage form of the drug changes. The modern antibiotic ciprofloxacin in its annotation has a wide group of diseases, for which it should be prescribed:

1. Infectious diseases of the genitourinary system: salpingoophoritis, prostatitis, urethritis, cystitis, adnexitis, pyelonephritis.
2. Peritonitis.
3. Bone and skin lesions: erysipelas, furunculosis, arthritis, bedsores, osteomyelitis.
4. infectious diarrhea.
5. Sepsis.
6. Anthrax.
7. ENT organs and respiratory system: tonsillitis, bronchitis, otitis media, pneumonia, sinusitis.
8. Infectious diseases of the organs of vision.

In dentistry

The need for an antibiotic is determined by the attending physician. An inflammatory, infectious process can cause damaged gums after tooth extraction. With ordinary toothache, the drug is prescribed in case of osteomyelitis or periodontitis. It is highly recommended to prescribe ciprofloxacin after resection. Often the remedy is used for flux for treatment at home. An antibiotic is used for infectious and purulent diseases in the form of tablets of 0.25 and 0.5 g. The dosage of the drug should be determined by a specialist on an individual basis.

With angina

The antibiotic ciprofloxacin actively fights most bacteria that can cause angina: meningococcus, pneumococcus, Haemophilus influenzae. The drug is effective even against strains resistant to tetracyclines, penicillins, aminoglycosides. With staphylococcus and streptococcus, the drug copes selectively, depending on the type of bacteria. Before prescribing the drug, sowing should be done to ensure the effectiveness of the use of the drug.

For the treatment of prostatitis

The inflammation that occurs with prostatitis is effectively treated with antibiotics. Often, the doctor prescribes taking ciprofloxacin-promed, which can be called the primary indication for getting rid of the problem. The drug is used in the treatment of acute, chronic prostatitis in men at any age. It is recommended to take the medication in complex therapy. The dosage during treatment is as follows:

1. In the chronic form of prostatitis, 125-750 mg is prescribed twice a day for 4-6 weeks.
2. In the acute form of bacterial prostatitis, 500 mg of the drug is prescribed 2 times a day for 2 weeks.

With cystitis

The unique antibacterial properties of ciprofloxacin make it possible to use the drug to combat any form of cystitis. This remedy will be the first thing the doctor will prescribe when drawing up a course of therapy. The dosage and method of application of the remedy will differ depending on the form of cystitis. In the form of tablets, according to the rules, the drug is taken on an empty stomach, washed down with a large amount of liquid. The duration of treatment, dosage depend on the severity of cystitis, as a rule, it is up to 10 days. The antibiotic is taken for another 2 days after the symptoms disappear.

ENT diseases

ENT organs are very susceptible to inflammatory processes. Because of this, the drug ciprofloxacin is effective in the treatment of such diseases. The appointment of the drug is permissible only after the appropriate tests have been carried out by a doctor. The drug acts on the infection, killing it. The dosage for ENT diseases depends on the infection, as a rule, the doctor prescribes ciprofloxacin in the form of tablets of 250 mg or 500 mg.

Contraindications and side effects

1. Do not take a child under 18 years of age, because the drug can affect the process of skeletal formation.
2. Diseases of tendons, ligaments.
3. During pregnancy, during breastfeeding.
4. Do not take if epileptic seizures occur.
5. In the presence of personal intolerance to the components of the drug.
6. Do not take concomitantly with tizandine.

Some patients are interested in whether it is possible to drink alcohol together with taking the drug. It should be understood that ciprofloxacin is a potent drug, so it is forbidden to combine it with alcohol. The interaction of the drug with strong drinks can lead to unpleasant side effects or a decrease in the effect of medicinal components, for example:

1. The drug and alcohol have a double toxic effect on the liver, destroying it.
2. The presence of alcohol in the blood increases the risk of side effects.
3. The drug enhances the effect of alcohol on the human condition, and the effectiveness of the drug is significantly reduced.

Doctors strongly recommend giving up alcohol not only during the course of therapy, but also for the next 2 days, so that the medication is completely eliminated from the body. The daily dosage of the drug is prescribed by the doctor based on the tests. There are situations in which overdose symptoms appear or side effects occur.

Overdose

• abdominal pain;
• dizziness;
• diarrhea;
• vomit;
• hand tremor;
• headache;
• hallucinations;
• convulsive activity;
• blood in the urine;
• hepatic, renal failure.

Side effects

• skin rash, itching;
• bloating;
• diarrhea, nausea, vomiting;
• sleep disturbance;
• double vision;
• intestinal dysbacteriosis;
• weakness;
• hepatitis;
• cardiopalmus;
• anemia;
• dizziness.

Video about the effectiveness of ciprofloxacin

Ciprofloxacin is an antibiotic that has a bactericidal effect against a wide range of pathogenic microorganisms. It does not slow down or stop the development and reproduction of microworld objects, as bacteriostatic drugs do, but completely destroys bacteria, causing their death and subsequent elimination from the body. The mechanism of action of this antibiotic is based on the inhibition of bacterial DNA gyrase, an enzyme responsible for DNA duplication, without which the process of protein synthesis is unthinkable.

Among the bacteria to which ciprofloxacin extends its action, there are both gram-negative and gram-positive specimens. Bacteria of the genus Staphylococcus, Streptococcus, Enterobacteria, Escherichia and Haemophilus influenzae, Klebsiella, Morganella, Neisseria, Salmonella, Shigella, Legionella, Providence, Yersinia, Chlamydia, Mycobacterium and many others are sensitive to it.

The use of ciprofloxacin is associated with a number of restrictions. So, while undergoing treatment with this drug, it is necessary to refrain from excessive exposure to the open sun. An important condition for the effective operation of the drug is the consumption of a sufficient volume of fluid to maintain diuresis at a normal level (otherwise, hemato- and crystalluria may occur).

The method of administration and dose of ciprofloxacin are determined on an individual basis, depending on the severity of the course and localization of the infection in the body, the age and body weight of the patient, his general health in general and the functional state of the urinary system in particular.

The recommended single dose for tablets is 250 mg for uncomplicated and 500 mg for complex infections, taken twice daily. The drug is taken on an empty stomach along with plenty of liquid. The average course of treatment with ciprofloxacin is 7 to 10 days. In severe infections, the drug can be used as an intravenous infusion of 400 mg twice a day (a detailed list of antibiotic doses depending on the disease is given in the package insert). In ophthalmic and ENT practice, ciprofloxacin is used topically in the form of eye and ear drops. For mild and moderate eye infections, it is enough to instill 2 drops of the drug into the conjunctival sac every 4 hours, for severe - every hour. Eye ointment, as a dosage form of ciprofloxacin, is currently not widely used and is produced by only one plant - the Russian JSC Tatkhimfarmpreparaty. In otolaryngology, the recommended dose of ciprofloxacin is 3-4 drops instilled into the external auditory canal 2-4 times a day.

Pharmacology

A broad-spectrum antimicrobial agent of the fluoroquinolone group. It has a bactericidal effect. Suppresses DNA gyrase and inhibits the synthesis of bacterial DNA.

Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae.

Active against Staphylococcus spp. (including strains producing and not producing penicillinase, methicillin-resistant strains), some strains of Enterococcus spp., Campylobacter spp., Legionella spp., Mycoplasma spp., Chlamydia spp., Mycobacterium spp.

Ciprofloxacin is active against bacteria producing beta-lactamase.

Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroides are resistant to ciprofloxacin. The action against Treponema pallidum has not been studied enough.

Pharmacokinetics

Release form

100 ml - polyethylene bottles (1) - cardboard packs.
100 ml - polyethylene bottles (50) - cardboard boxes.

Dosage

Individual. Inside - 250-750 mg 2 times / day. Duration of treatment - from 7-10 days to 4 weeks.

For intravenous administration, a single dose is 200-400 mg, the frequency of administration is 2 times / day; duration of treatment - 1-2 weeks, if necessary, and more. Can be given by intravenous bolus, but drip over 30 minutes is more preferred.

When applied topically, 1-2 drops are instilled into the lower conjunctival sac of the affected eye every 1-4 hours. After the condition improves, the intervals between instillations can be increased.

The maximum daily dose for adults when taken orally is 1.5 g.

Interaction

With the simultaneous use of ciprofloxacin with didanosine, the absorption of ciprofloxacin is reduced due to the formation of ciprofloxacin chelators with the aluminum and magnesium buffers contained in didanosine.

With simultaneous use with warfarin, the risk of bleeding increases.

With the simultaneous use of ciprofloxacin and theophylline, it is possible to increase the concentration of theophylline in the blood plasma, increase the T 1/2 of theophylline, which leads to an increased risk of developing toxic effects associated with theophylline.

Simultaneous administration of antacids, as well as preparations containing aluminum, zinc, iron or magnesium ions, can cause a decrease in the absorption of ciprofloxacin, so the interval between the appointment of these drugs should be at least 4 hours.

Side effects

From the digestive system: nausea, vomiting, diarrhea, abdominal pain, increased activity of hepatic transaminases, alkaline phosphatase, LDH, bilirubin, pseudomembranous colitis.

From the side of the central nervous system: headache, dizziness, fatigue, sleep disorders, nightmares, hallucinations, fainting, visual disturbances.

From the urinary system: crystalluria, glomerulonephritis, dysuria, polyuria, albuminuria, hematuria, transient increase in serum creatinine.

From the hematopoietic system: eosinophilia, leukopenia, neutropenia, changes in platelet count.

From the side of the cardiovascular system: tachycardia, cardiac arrhythmias, arterial hypotension.

Allergic reactions: pruritus, urticaria, angioedema, Stevens-Johnson syndrome, arthralgia.

Adverse reactions associated with chemotherapeutic action: candidiasis.

Local reactions: soreness, phlebitis (with intravenous administration). When using eye drops, in some cases, mild soreness and hyperemia of the conjunctiva are possible.

Other: vasculitis.

Indications

Infectious and inflammatory diseases caused by microorganisms sensitive to ciprofloxacin, incl. diseases of the respiratory tract, abdominal cavity and pelvic organs, bones, joints, skin; septicemia; severe infections of the upper respiratory tract. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.

For local use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meibomitis. Infectious lesions of the eyes after injuries or foreign bodies. Preoperative prophylaxis in ophthalmic surgery.

It has been found in experimental studies to cause arthropathy.

Application for violations of kidney function

Use in children

Contraindicated in children and adolescents under 15 years of age.

special instructions

Dosage adjustments are required in patients with impaired renal function. Use with caution in elderly patients, with cerebral atherosclerosis, cerebrovascular accidents, epilepsy, convulsive syndrome of unclear etiology.

During treatment, patients should receive sufficient fluids.

In case of persistent diarrhea, ciprofloxacin should be discontinued.

With simultaneous intravenous administration of ciprofloxacin and barbiturates, monitoring of heart rate, blood pressure, ECG is necessary. In the process of treatment, it is necessary to control the concentration of urea, creatinine, and hepatic transaminases in the blood.

During the period of treatment, a decrease in reactivity is possible (especially when used simultaneously with alcohol).

Do not administer ciprofloxacin subconjunctivally or directly into the anterior chamber of the eye.

Ciprofloxacin is an antibiotic that has a wide spectrum of action. The drug belongs to the fluoroquinolones. Accordingly, ciprofloxacin has a pronounced antimicrobial activity. The mechanism of the drug is as follows: the antibiotic disrupts the process of division and synthesis of DNA in bacteria. This causes morphological changes and rapid death of the bacterium.

Ciprofloxacin has been used for many years. The drug was developed by Bayer in 1983. Already 4 years later, after passing clinical trials, the drug was approved for oral use in the form of tablets.

Common Applications

Ciprofloxacin is used for a number of different diseases. Often, an antibiotic is prescribed for bacterial infections, the causative agents of which are sensitive microorganisms. Ciprofloxacin is effective in the fight against staphylococci, mycoplasmas, legionella, chlamydia, mycobacteria, enterococci.

Ciprofloxacin is often used in the field of surgery. An antibiotic is often prescribed in the postoperative period. In addition, ciprofloxacin, in the form of tablets and injections, is used in the treatment of purulent skin diseases. The medicine can even help with sepsis.

For many years, ciprofloxacin has been quite successfully used in pulmonology. As a rule, it is referred to as second-line drugs. This means that ciprofloxacin is prescribed in cases where the use of other antibiotics has failed. In addition, the drug is used to treat severe infectious diseases that affect the respiratory tract.

Ciprofloxacin is effective for the treatment of lung abscess, pleurisy and pneumonia. For the treatment of the above diseases, the drug is used in injection form.

Other applications

Ciprofloxacin is also actively used in ENT diseases. For example, an antibiotic may be prescribed to treat sinusitis or chronic inflammation of the middle ear. In addition, ciprofloxacin is used for otitis media, which are difficult to treat. In this case, the course of taking the drug lasts several months.

Urology is another area in which ciprofloxacin is used. With the help of this antibiotic, such male diseases are treated. For example, the drug is used for cystitis, prostatitis, acute or chronic pyelonephritis. In turn, infectious disease specialists use ciprofloxacin to treat diseases such as dysentery and salmonellosis.

The drug is used to treat mixed infections (aerobic and anaerobic). However, in addition to ciprofloxacin, lincosamides or metronizadol are also prescribed. This is due to the fact that some pathogens of mixed infections have a certain resistance to the drug.

Ciprofloxacin is also used in dentistry. Sometimes, after the extraction of a tooth, an inflammatory process may follow. In this case, ciprofloxacin is prescribed. Also, the medication is prescribed after a tooth resection. The drug may be prescribed to relieve pain in periodontitis or osteomyelitis.

Dosage forms

Since ciprofloxacin has a wide range of applications, the drug is produced in various drug forms. Depending on the severity and location of the infection, the drug can be prescribed in the form of:

• tablets;
• ampoules;
• ear and eye drops;
• ointments.

Tablets are the most common form for ciprofloxacin. In this form, the medicine is easy to store, transport and use. This drug form is recommended for the treatment of intestinal diseases. After all, the drug in tablets provides quick access to the source of infection.

Ciprofloxacin ampoules are used for injection. The agent is administered in the amount of two hundred milligrams through a dropper. In the form of ampoules, ciprofloxacin is used for almost any infection with complications.

Ciprofloxacin drops are used when the focus of infection is located in the eye or ears. The drug is produced as a solution containing 0.3% of the active substance. The drops have a yellow tint and contain ciprofloxacin hydrochloride (3 grams).

An antibiotic in the form of an ointment is usually used to treat eye diseases. In small quantities, the medicine is placed under the lower eyelid several times a day. Also, the ointment is prescribed for the treatment of skin areas that have been affected by infection.

Ciprofloxacin. Instruction

The dosage of the drug depends on the disease and its severity. For example, for the treatment of urinary tract infections, ciprofloxacin is used in the form of tablets (0.25 - 0.5 grams twice a day). In more severe diseases, the dose is increased to 0.75 grams every 12 hours.

Sometimes there are severe cases when the patient is simply not able to take pills or their use is ineffective. Then ciprofloxacin is used as an injection.

Ampoules containing 1% of the active substance are diluted in a solution of sodium chloride or glucose.

The need to prescribe ciprofloxacin is determined by the attending physician. He, having assessed the severity of the disease and the location of the infection, determines the dosage and dosage form. The duration of the course also varies. The duration of treatment can vary from 10 days to a couple of months.

Contraindications

Ciprofloxacin, like most drugs, has certain contraindications. The drug is dangerous for children, pregnant women and lactating women. In addition, the drug should not be used until the age of 18. This is due to the fact that ciprofloxacin affects the formation of bone tissue. It is for this reason that the drug is not prescribed during intensive growth.

However, there are also exceptions. For example, a disease called cystic fibrosis, which is hereditary. This disease disrupts the production of secretions in the bronchi. Because of this, the patient suffers from persistent respiratory tract infections. In the treatment of cystic fibrosis in children, other antibiotics are ineffective. Therefore, the use of ciprofloxacin is a necessity.

Side effects

It is worth noting that ciprofloxacin can be called safe. The drug does not have a negative effect on the cells of an adult. And the structures that ciprofloxacin destroys are present only in bacteria. Therefore, the drug causes side effects in only 10% of cases.

These include gastrointestinal disorders (vomiting, diarrhea, etc.), headache, sleep problems, allergic reactions, etc. In rare cases, the number of lymphocytes or leukocytes in the blood may decrease.

Analogues

Ciprofloxacin has been popular for many years. This is due to the fact that the drug is incredibly effective. Most bacteria are not resistant to this antibiotic. In addition, ciprofloxacin is inexpensive and completely safe for adults. The popularity of the tool has led to the fact that in the modern market there are a huge number of analogues from various companies. Ciprofloxacin in pharmacies has more than 30 items. For example:

• citeral;
• Cyprosandosis;
• Ciprobay;
• Tsiprinol.

Ciprofloxacin has indirect analogues. These include antibiotics, which also belong to the group of fluoroquinolones, but at the same time belong to other generations. The difference between ciprofloxacin and other drugs of the fluoroquinol group lies in the sensitivity to different types of bacteria. It is worth noting that only the attending physician can replace ciprofloxacin with a drug of another generation.

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The group of fluoroquinolones, to which the antibiotic Ciprofloxacin belongs, appeared relatively recently. The first drug of this type began to be used only in the 1980s. Previously, antibacterial agents of this class were prescribed only for urinary tract infections. But now, due to their broad antimicrobial activity, fluoroquinolones, including the antibiotic Ciprofloxacin, are prescribed for bacterial pathologies that are difficult to treat, or for an unidentified pathogen.

The mechanism of the bactericidal action of this drug is based on the penetration of a pathogenic microorganism through the cell membrane and the effect on reproduction processes.

Fluoroquinolones inhibit the synthesis of bacterial enzymes that determine the twisting of the DNA strand around nuclear RNA, this is type I topoisomerase in gram-negative bacteria and class IV topoisomerase in gram-positive ones.

The antibiotic Ciprofloxacin is active against a wide range of bacteria that are resistant to most antimicrobial drugs (Amoxicillin and its more effective analogue Amoxiclav, Doxycycline, Tetracycline, Cefpodoxime and others).

As indicated in the instructions for use, the following strains of bacteria are sensitive to the action of Ciprofloxacin:

• golden and saprophytic staphylococcus aureus;
• the causative agent of anthrax;
• streptococcus;
• legionella;
• meningococcus;
• yersinia;
• gonococcus;
• hemophilic bacillus;
• moraxella.

E. coli, enterococci, pneumococci and some strains of Proteus have moderate sensitivity. Resistant to the action of the antibiotic Ciprofloxacin are mycoplasmas and ureaplasmas, listeria and other, infrequent bacteria.

The drug belongs to the second generation fluoroquinolones, while its analogue of the same group, no less common Levofloxacin, belongs to the third generation and is more used for the treatment of diseases of the respiratory tract.

The advantage of the antibiotic Ciprofloxacin is a wide choice of forms of release. So, for the treatment of bacterial eye infections to reduce the risk of systemic side effects, the drug is prescribed in the form of eye drops. In severe diseases, injections of Ciprofloxacin are necessary, or rather, infusions, the standard dosage is 100 mg - 200 mg / 100 ml. After normalization of the patient's condition, the patient is transferred to tablets (they are available with a concentration of the active ingredient of 250 and 500 mg). Accordingly, the price of the drug also differs.

The main ingredient of the drug is ciprofloxacin, the presence of excipients depends on the specific form of release of the antibiotic. In the solution for infusions, it is purified water and sodium chloride, in eye drops - various solvents and stabilizers, in tablets - talc, silicon dioxide, cellulose.

The antibiotic Ciprofloxacin is prescribed for children from 5 years of age and adults to treat such diseases:

• lesions of the lower respiratory tract, including pneumonia, caused by flora sensitive to fluoroquinolones;
• infections of ENT organs, including tonsillitis, otitis media, sinusitis;
• diseases of the genitourinary system, for example, cystitis, pyelonephritis, urethritis, gonorrhea, bacterial prostatitis, adnexitis;
• various intestinal infections (shigellosis, salmonellosis, typhoid fever, cholera, enteritis, colitis);
• sepsis, peritonitis;
• infections affecting the skin, soft tissues, bones and cartilage, bacterial complications after burns;
• anthrax;
• brucellosis;
• yersiniosis;
• borreliosis;
• tuberculosis (as part of complex therapy);
• specific prophylaxis of bacterial infections in patients with immunodeficiency on the background of HIV or AIDS or the use of cytostatics.

In the form of eye drops, the antibiotic Ciprofloxacin is prescribed for infections of the mucous membrane of the organs of vision. According to experts, cases of development of resistance of the bacterial flora to the action of the drug have not been identified to date. But fluoroquinolones are classified as unsafe drugs, so they are not considered as first-line drugs for the treatment of uncomplicated bacterial infections.

Ciprofloxacin intramuscularly and in the form of eye drops and tablets

When taken orally, the antibiotic is absorbed fairly quickly, mainly these processes occur in the lower parts of the digestive tract. The maximum concentration is reached in an hour and a half after the use of Ciprofloxacin tablets. The overall bioavailability of the drug is high and is about 80% (the exact concentration of the active ingredient in the body depends on the dose taken).

Only dairy products affect the absorption of the antibiotic, so they are advised to be excluded from the diet for the duration of treatment. Otherwise, food intake somewhat slows down the absorption of Ciprofloxacin, but the bioavailability indicators do not change.

With plasma proteins, the active component of the drug binds only 15-20%. Basically, the antibiotic is concentrated in the organs of the small pelvis and abdominal cavity, saliva, lymphoid tissue of the nasopharynx, and lungs. Ciprofloxacin is also found in synovial fluid, bone and cartilage tissue.

The drug enters the spinal canal in a small amount, so it is practically not prescribed for lesions of the central nervous system. Approximately one third of the total dosage of Ciprofloxacin is metabolized in the liver, the rest is excreted by the kidneys in unchanged form. The half-life is 3-4 hours.

The exact amount of medication prescribed, as well as the duration of treatment, depends on many factors. First of all, it is the condition of the patient. The standard recommendation regarding the use of any antibacterial agent is to continue taking it for at least three days after the temperature has returned to normal. This applies to both oral forms and the use of Ciprofloxacin intramuscularly.

For adults, the dosage of the drug is 500 mg twice a day, regardless of the meal.

The annotation to the drug indicates the average duration of therapy:

• with diseases of the respiratory tract - up to two weeks;
• with lesions of the digestive system from 2 to 7 days, depending on the severity of the clinical picture and the causative agent of infection;
• in diseases of the genitourinary system, prostatitis therapy lasts the longest - up to 28 days, to eliminate gonorrhea, a single dose is sufficient, with cystitis and pyelonephritis, treatment is continued up to 14 days;
• with infections of the skin and soft tissues - an average of two weeks;
• with bacterial lesions of bones and joints, the duration of therapy is determined by the doctor and can last up to 3 months.

Important

The severe course of the infection is an indication for increasing the daily dosage for an adult to 1.5 g.

Important

The maximum daily dosage of the drug in childhood should not exceed 1.5 g per day.

Ciprofloxacin is not used intramuscularly. The antibiotic solution is administered only intravenously. At the same time, its action develops much faster than that of tablets. The maximum plasma concentration is reached after 30 minutes. The bioavailability of the Ciprofloxacin solution is also higher. With intravenous injections, it is almost completely excreted unchanged by the kidneys within 3-5 hours.

Unlike tablets, for many uncomplicated bacterial diseases, one infusion of Ciprofloxacin is sufficient. In this case, the daily dosage for adults is 200 mg or two injections during the day. The required amount of the drug for a child is determined in the proportion of 7.5-10 mg / kg per day (but not more than 800 mg per day).

The ready solution for infusion is produced not in small ampoules, but in 100 ml vials, the concentration of the active substance is 100 or 200 mg. The drug can be used immediately, it does not require further dilution.

Eye drops with ciprofloxacin are intended for the treatment of various infectious eye lesions (conjunctivitis, blepharitis, keratoses and ulcers) caused by sensitive flora. Also, the drug is prescribed to prevent postoperative and post-traumatic complications.

The total volume of the bottle with drops is 5 ml, while 1 ml of the solution contains 3 mg of active ciprofloxacin. With moderately severe symptoms of the disease and for prophylactic purposes, the drug is prescribed 1-2 drops in each eye every four hours. In complicated infections, the frequency of use is increased - the procedure is repeated every two hours.

Ofloxacin or Ciprofloxacin: which is better, other analogues of the drug, restrictions on use

The use of the drug is strictly contraindicated during pregnancy and lactation. In addition, Ciprofloxacin affects the formation of the structure of bone and cartilage tissue, so children under 18 years of age are prescribed it only for strict medical reasons.

Also, contraindications to taking the medicine are hypersensitivity not only to Ciprofloxacin, but also to other medicines from the fluoroquinolone group.

The use of an antibiotic should be carried out under strict medical supervision in violation of the excretory function of the kidneys, severe diseases of the central nervous system. If the use of Ciprofloxacin is started after an operation under general anesthesia, monitor the pulse and blood pressure.

Unlike other, safer antibacterial drugs from the class, for example, penicillins, the risk of adverse reactions during therapy with ciprofloxacin is high.

The patient is warned about such possible side effects:

• impaired visual clarity and color perception;
• the occurrence of a secondary fungal infection;
• digestive disorders, accompanied by vomiting, nausea, heartburn, diarrhea, inflammatory lesions of the intestinal mucosa rarely develop;
• dizziness, headache, sleep disorders, anxiety and other psycho-emotional disorders, sometimes convulsions;
• hearing loss;
• acceleration of heart rate, arrhythmias against the background of low blood pressure;
• shortness of breath, impaired lung function;
• disorders of the hematopoietic system;
• deterioration of kidney and liver function;
• rashes, itching, swelling.

Ciprofloxacin is part of many drugs.

So, instead of this medication, the doctor may prescribe the following medications to the patient:

• Tsiprolet (solution for infusion, eye drops, tablets of 250 and 500 mg);
• Betaciprol (eye drops);
• Quintor (tablets and infusion solution);
• Tsiprinol (in addition to injection and conventional tablets, there are also capsules with prolonged action);
• Ciprodox (tablets with a dosage of 250, 500 and 750 mg).

If we talk about analogues of this antibiotic, we should also mention other antibacterial agents from the group of fluoroquinolones. So, patients are often interested in the doctor, Ofloxacin or Ciprofloxacin, which is better? Or can it be replaced with more modern Norfloxacin or Moxifloxacin?

The fact is that the indications for use for all of these funds are the same. Like Ciprofloxacin, they work well against the main pathogens of cystitis, pneumonia, prostatitis and other infections. But doctors emphasize that the "older" generation of fluoroquinolone, the greater its activity against pathogenic flora. But at the same time, the risk of severe adverse reactions also increases.

Therefore, the question Ofloxacin or Ciprofloxacin, which is better is not entirely correct. An antibiotic should be prescribed solely on the basis of the identified pathogen and the general condition of the patient. In other words, if the doctor sees that Ciprofloxacin will cope with, for example, pyelonephritis, then there is no need to prescribe a stronger, but less safe Norfloxacin or Lomefloxacin.

As for the cost of an antibiotic, it largely depends on the manufacturer and the purity of the substance used to manufacture the drug. So, domestic eye drops with Ciprofloxacin cost from 20 to 30 rubles. A package of 10 tablets with a dosage of 500 mg will cost 120-150 rubles. The cost of one vial of solution for infusion ranges from 25-35 rubles.

Natalia, 50 years old

“Ciprofloxacin was prescribed to treat inflammation of the kidneys. Before that, other, weaker antibiotics were also prescribed, but only this drug helped. The first few days I had to endure droppers, then they switched to pills. I was also pleased with the low price of the medicine. ”

Given the high risk of dangerous adverse reactions, only a doctor should decide whether Levofloxacin or Ciprofloxacin is better. The drugs are quite toxic, therefore, it is additionally recommended to take biochemical and clinical blood and urine tests to prevent possible complications of therapy.