Genferon rectal suppositories instruction. Genferon - official * instructions for use. Indications for use for children

Genferon is an immunomodulatory medicine, the drug has antiviral action on the body. I will consider in detail its instructions for use.

What is the composition and form of release of Genferon?

Genferon is produced in yellowish-white suppositories, they are cylindrical in shape with a somewhat pointed end. Active substance- interferon human recombinant alpha-2, in addition, there is taurine and benzocaine.

Excipients Genferon: solid fat, purified water, dextran 60,000, citric acid, polyethylene oxide 1500, sodium citrate, tween-80 added, and emulsifier T2.

Suppositories of five pieces are packed in cell packs and placed in cardboard packs, on which their expiration date is visible, it is two years from the date of release of the drug. It is recommended to place the medication in cool conditions from two to eight degrees. You can buy Genferon on a prescription form.

What is the effect of the drug Genferon?

The combined drug Genferon has a local immunomodulatory effect on the body, as well as a systemic one. Interferon alpha-2 also has antiviral and antimicrobial effects.

Under its influence, the activity of phagocytes, natural killers, in addition to T-helpers, is enhanced, and the differentiation of B-lymphocytes is also improved. Interferon inhibits the replication of chlamydia, as well as the transcription of viruses.

Another active ingredient drug Genferon - taurine, it has a membrane-protective, antioxidant effect, as well as an anti-inflammatory effect, in addition, it enhances regenerative processes in tissues.

Another component is benzocaine, it has a local anesthetic effect, reduces the permeability cell membranes directly for sodium ions, while calcium is displaced from inner surface membranes, which leads to blocking of the nerve impulse. This substance prevents the occurrence of pain impulses.

The drug is absorbed through the mucous membrane with rectal or vaginal application, after which it enters the tissues, into lymphatic system, resulting in a systemic effect of Genferon on the body. In addition, he provides local action.

What are the indications for the use of the drug Genferon?

Rectal suppositories Genferon are prescribed as part of complex treatment for infectious and inflammatory processes occurring in the urogenital tract:

Shown remedy for genital herpes;
The drug is effective for chlamydia and ureaplasmosis;
Assign suppositories for mycoplasmosis;
With trichomoniasis;
With vaginal candidiasis of a recurrent nature;
Apply the drug for gardnerellosis and trichomoniasis;
With cervicitis and with;
With papillomavirus infection;
Effective remedy for bacterial vaginosis;
With erosion of the cervix;
A drug is prescribed for urethritis, vulvovaginitis, adnexitis and prostatitis.

In addition, the drug is effective in the presence of balanitis and balanoposthitis.

What are the contraindications for Genferon?

The drug Genferon is not used for hypersensitivity to its components.

What is the use and dosage of Genferon?

In diseases of the urogenital tract of an infectious and inflammatory nature, Genferon is used intravaginally, one suppository twice a day, the treatment period is designed for ten days. At chronic processes the drug is used every other day for one or three months.

For men, with diseases of the urogenital tract, the drug is prescribed rectally, also one suppository twice a day, the treatment lasts at least ten days.

At joint application Genferon with antibiotics or other antimicrobial drugs intended for the treatment of urogenital pathology, its effectiveness increases markedly.

With the simultaneous appointment of the drug with vitamin E or c ascorbic acid, the effect of interferon is enhanced. NSAIDs, as well as anticholinesterase agents, potentiate the effect of benzocaine.

Before using medicinal suppositories, it is first recommended to consult a doctor, and only then proceed to therapeutic activities.

Overdose Genferon

About cases of overdose of Genferon, the instructions for use do not provide information, since there is none yet.

What are the side effects of Genferon?

The use of suppositories can lead to the development of some allergic reactions in the form of skin itching and rashes, these symptoms are reversible, they disappear without a trace three days after the drug is discontinued.

When using Genferon at a dosage of 10 million IU / day, the risk of developing such side effects may increase: the patient develops headache, leukopenia, thrombocytopenia are noted, body temperature may rise, hyperhidrosis occurs, fatigue, myalgia are not excluded, appetite decreases, and arthralgia develops.

special instructions

The drug should be used with caution in patients with a history of autoimmune or allergic diseases, especially those occurring in the acute stage.

What are Genferon analogues?

Interferon alfa-2b + Taurine refers to analogues, the remedy should be used after consulting a doctor.

Conclusion

Treatment of urogenital infection should be carried out after examining the patient, in the presence of side effects, you should consult a specialist.

Having learned after going to the pharmacy the cost of some prescribed drugs, sometimes it’s time to turn to a specialist again - a cardiologist or a psychologist - it all depends on the health and the amount. However, there are drugs that allow you to save money, as they contain several active ingredients at once, for example, Genferon candles. What can they save us from?

Suppositories Genferon are prescribed for the treatment of urogenital diseases caused by viruses, fungi and bacteria. This medicine is prescribed for:

• toxoplasmosis;
• chlamydia;
• mycoplasma;
• any type of herpes;
• vaginal candidiasis;
• trichomoniasis;
• erosion of the cervix;
• cervicitis;
• adnexitis;
• weakened defensive forces organism.

The drug is often prescribed precisely as an immunostimulant, especially for children.

Candles are inserted into the anus or into the vagina 1-2 times, depending on the nature of the disease and the age of the patient. But before dwelling on the nuances of taking, let's figure out what the effect of the drug is based on. Genferon is a combination of three components:

• interferon (helps the blood to develop its own immunity, and also provides additional interferons - substances formed in the blood during the reaction to viruses entering the body);
• taurine (increases interferon, and also accelerates the regeneration of tissue cells, reducing the area of ​​the inflammatory process);
• benzocaine (has an analgesic property).

Such wide range exposure allows you to effectively stimulate the activity of your own immunity.

Nuances of application

Each suppository contains different amount interferons - from 125 to 1000. Depending on the severity of the course of the disease, a weaker or strong medicine. The dosage is determined solely by the doctor on the basis of diagnostic procedures and general condition patient.

Treatment of women

If a woman has an acute genital infection, then, as a rule, it is prescribed 1 suppository vaginally with a dosage of 250-500. You need to use suppositories 2 times a day. The course of treatment is not recommended to delay more than 10 days. Otherwise, irreversible processes associated with “relaxation” may begin in the body. immune system, which gets used to the fact that interferon insures it.

If the lady is being treated for a protracted infection, then the regimen is somewhat different: 1 suppository at bedtime, but for 1-3 months.

Treatment for men

Representatives strong half mankind prescribe Genferon 500 to increase immunity, as well as complex therapy both sexual partners. Suppositories are applied 2 times a day, after waking up and before going to bed. The course of treatment in this case is about 10 days.

Help for children

Doctors prescribe Genferon from the first days after birth. However, this is possible and advisable only if the baby’s immunity is really weakened, which does not allow him to overcome the infection on his own. Also, the drug is used in cases of preparation for surgery.

For children, Genferon light suppositories are usually prescribed with a dosage of 125 to minimize a possible allergic reaction.

The intensity of treatment depends on the nature of the disease:

Candles Genferon during pregnancy and lactation

Women in the position of suppositories are prescribed only from the 2nd trimester. This is due to the fact that, by activating the protective properties of the immune system, it is possible to provoke the rejection of the fetus being born as a foreign organism. The dosage is calculated individually, depending on the severity of the infection. When lactation, the drug is not prescribed.

Feedback

The instructions for candles "Genferon Light" 125 for children say that this drug stimulates the body's immune abilities after 1-2 doses. This is confirmed by the reviews of mothers, who in this way helped their babies recover more quickly after viral or infectious diseases. The leitmotif of reviews about taking Genferon suppositories for children can be considered the fact that young patients did not experience allergic reactions, but a noticeable therapeutic effect it's already been 2 days.

But women who use Genferon vaginally often complain of a burning sensation in the perineum, violations monthly cycle and heartburn. The last "side effect" is also noted by men. On the whole high efficiency The drug allows you to "forgive" him some minor flaws.

Having found out what Genferon candles are and what they are from, you should not immediately rush to buy far from cheap drug. Still, it is better to contact a doctor who can draw a conclusion about how useful suppositories will be for a particular patient. And you should be especially careful when treating children and pregnant women, although in their case this drug is also used and gives a good effect.

Latin name: Genferon
ATX code: L03AB05
Active substance: Interferon
alpha 2b + Taurine + Benzocaine
Manufacturer: Biocard, Russia
Pharmacy leave condition: On prescription
Price: from 350 to 750 rubles.

"Genferon" is an immunomodulator and at the same time an antiviral agent. Its use allows you to effectively deal with various inflammatory processes and a number of pathogens of infectious diseases. First of all, this drug is used for diseases genitourinary system in women and men (thrush, genital herpes, papillomas, cystitis, prostatitis and others).

If the drug is administered rectally, the systemic effect of its use is achieved, which makes it possible to treat viral and bacterial diseases respiratory system, as well as engage in the prevention of diseases, by increasing immunity. For those to whom the doctor prescribed "Genferon", instructions for its use are simply necessary.

Indications for use

Reception of "Genferon" is shown at various infectious diseases, the causative agents of which are viruses, bacteria, protozoa, fungi. It is used to treat:

• Diseases of the male and female genital area caused by the herpes virus, HPV (human papillomavirus), gardnerella, mycoplasma, ureplasma, chlamydia, trichomonas, candida and other microorganisms
• Colds - ARI and ARVI, acute bronchitis etc.
• Diseases urinary tract, in particular, bacterial chronic cystitis.

Read about the dangers of diseases of the genitourinary system in the article:.

Compound

It includes three active ingredients that complement each other in medicinal properties:

• Human interferon alpha-2b, recombinant (rhIFN-α-2b). Obtained by synthesis coli who have received the corresponding gene. It has a pronounced immunomodulatory, antiviral and antibacterial action
• Taurine. Antioxidant and membrane stabilizer. Raises efficient work interferon, as well as repair of damaged tissues
• Benzocaine (sometimes an anesthetic is used instead). A local anesthetic.

In addition to the main active ingredients, candles include additional substances: solid fat and others (T2 emulsifier, sodium citrate, purified water, and others).

Medicinal properties

"Genferon" candles can be used:

• Rectally. In this case, it provides complex impact on the body, since the drug is well absorbed into the blood and lymph flow through the mucous membrane of the rectum
• Vaginally. The permeability of the vaginal epithelium is much lower than that of the intestine. Therefore, in this case, the local action of “Genferon” is achieved.

Pharmacological features of the drug are determined by the combined effect of the impact of its constituent parts:

• Interferon alpha-2b has an antiviral effect by suppressing the replication of viruses (HPV, herpes, and others). The immunomodulatory effect is achieved by increasing the concentration of phagocytes, monocytes, macrophages and other cells related to natural killers. This contributes to the immune response to infection, the destruction of its foci and the resumption of the production of Ig A antibodies there. Mediated immunoreactions cause antimicrobial action"Genferon"
• Taurine catalyzes the action of interferon; plays an antioxidant role, removing reactive oxygen species and thereby reducing inflammatory processes; promotes cellular regeneration
• Benzocaine blocks pain impulses in nerve cells which produces a local anesthetic effect. It is not absorbed into the blood, affecting the injection site.

The concentration of the main active substance - interferon - decreases after 12 hours. Therefore, in order to achieve maximum therapeutic effect the drug should be used twice a day. Its components are excreted from the body by the kidneys.

The average price is from 350 to 750 rubles.

Release forms

"Genferon" candles are cone-shaped suppositories with a pointed tip. The color is white, there may be a light yellow tint. Due to the excipients, they do not melt in the hands, which is convenient when administered.

There are four types of suppositories that differ in the concentration of interferon: Genferon 1,000,000 IU, Genferon 500,000 IU, Genferon 250,000 IU and Genferon Light (which you can read about).

The carton can contain 5 or 10 suppositories packed in a plastic shell.

Mode of application

Candles are administered vaginally or rectally, depending on the gender of the patient, the nature of the disease and the prescribed therapy.

For the treatment of diseases of the genitourinary system, women are prescribed 2 times in 12 hours, one suppository with a dosage of 500 thousand IU or 1000 thousand IU. As a rule, this is a vaginal administration. The duration of treatment is up to 10 days. During treatment chronic form diseases are used three times a week for 1 candle, with an interval of one day, for 1-3 months.

You can use candles during menstruation.

With acute infectious inflammation complex therapy is used in the female genital tract:

1. In the morning vaginally Genferon 500 thousand IU
2. In the evening Genferon 1000 thousand IU rectally and additionally vaginal suppositories with an antibacterial effect (for example, Hexicon).

Men, in particular "Genferon" for prostatitis, are shown to use suppositories rectally twice a day, with a dosage of 500,000 or 1,000,000 IU, depending on the severity of the disease. Use the drug for no longer than 10 days.

Under the supervision of a doctor, you can use "Genferon" for children, with different dosages, depending on the age of the patient:

• 1-7 years old - a pediatrician may prescribe Genferon Light (125,000 IU)
• 7-14 years - the dosage is increased to 250 thousand IU
• Over 14 years old - dosages similar to adults: 250 thousand IU, 500 thousand IU, or 1,000,000 IU, depending on the severity of the disease.

Candles, which are slightly smaller than usual, are injected into the rectum after 12 hours. Duration of admission - 5 days. If the child has a relapse of a chronic disease or the disease has taken a protracted form, the doctor may add another 5-day course of treatment.

It is possible to use the drug with preventive purpose: one suppository at night, every other day. Preventive use of the drug is from 1 to 3 months.

During pregnancy and breastfeeding

When deciding whether to use "Genferon" for the treatment of pregnant women, the doctor must balance the benefits for the mother to the harm that can be done to the child. The drug is prescribed no earlier than the 12th week of pregnancy. This drug is used in systemic therapy with identified ureaplasma, thrush, herpes virus, HPV, cystitis and other viral and bacterial diseases.

"Genferon" is not prescribed during lactation.

Contraindications

It is forbidden to use candles when following conditions: the first trimester of pregnancy and an individual allergic reaction to the substances that make up it.

Precautionary measures

Restriction to the use of the drug are exacerbations of autoimmune diseases and allergies various etiologies.

"Genferon" and alcohol are combined in very small doses of the latter. It is not recommended to exceed it, since alcohol worsens the effect of interferon, but at the same time increases side effects. Therefore, "Genferon" and alcohol is a completely dubious combination, as in most cases with drugs.

Cross-drug interactions

The use of "Genferon" with vitamins E and C, which accelerate the action of interferon, is shown.

In complex therapy, the drug is prescribed with other antimicrobial drugs or antibiotics. For example, it goes well with vaginal suppositories"Terzhinan". They include:

• The antifungal agent nystatin
• Aminoglycoside antibiotic neomycin sulfate
• A substance of the imidazole group ternidazole, which works against anaerobic microorganisms, including Trichomonas and Gardnerella
• The corticosteroid prednisolone sodium metasulfobenzoate is a local anti-inflammatory agent.

"Terzhinan" with "Genferon" effectively interact with cystitis, thrush and other infectious diseases of the genitourinary system.

Another antiseptic, which perfectly interacts with “Genferon” - “Hexicon”. Its main active ingredient is chlorhexidine. Produced "Geksikon" in the form vaginal suppositories and solution. Effective against a number of infectious agents of various etiologies and locations.

Side effects

Basically meet local symptoms allergies: itching and burning in the vagina. They go away by themselves a couple of days after the end of the drug. The possibility of its further use should be discussed with your doctor.

When using suppositories per day with a total dose of 10,000,000 IU, reactions are possible that are characteristic of all types of interferon:

• From the side hematopoietic system- a decrease in the content of platelets and leukocytes in the blood (thrombocyto- and leukopenia)
• From the side of the central nervous system- headaches, loss of appetite, fatigue
• From the side musculoskeletal system– muscle and joint pain (myalgia and arthralgia)
• Others - hyperthermia ( fever body), hyperhidrosis (excessive sweating).

When the temperature rises, paracetamol or ibuprofen (Nurofen) can be used.

Overdose

Until this time, cases of excessive use of the drug have not been recorded.

Terms and conditions of storage

The drug can be stored in the refrigerator, at a temperature not lower than +2 and not higher than +8 degrees, away from children, no longer than two years from the date of manufacture.

Analogues

“ ”

Green oak forest, Russia
Price from 380 to 4200 rubles.

The main active ingredient is an extract from a plant of the nightshade family Solanum tuberosum. "Panavir" promotes the production of immunoglobulin A and leukocytes. It also increases the body's resistance to various pathogens of infectious diseases. The high efficiency of the drug "Panavir" for the fight against HPV is noted. After applying its various dosage forms, papillomas disappear.

pros

• Several dosage forms: solution for injection, gel for local application, rectal suppositories, inlight spray gel
• Has a bright antipyretic effect - no need to use additional funds
• Favorably affects the retina of the eyes, the regeneration of the gastric mucosa.

Minuses

• Not to be used by children under 12 years of age
• High price for injections.

“ ”

Feron, Russia
Price from 125 to 750 rubles.

Almost identical to "Genferon", since the main active substance is an interferon. "Viferon" is available in the form of a gel, ointment and rectal suppositories with a dosage of 150,000 IU, 500,000 IU, 1,000,000 IU, and 3,000,000 IU. First dosage forms are used in gynecology for the treatment of genital tract infections in women.

pros

• There are auxiliary substances - vitamins C and E, which enhance the effect of interferon
• Can be used from birth

Minuses

• Require special conditions storage
• The total cost of a course of treatment can be high.

Genferon is a unique drug obtained as a result of many years of research by Russian scientists at the Center for Engineering Immunology. It is a combination of recombinant human interferon alpha-2, taurine and anesthesin, is available in the form of vaginal and rectal suppositories.

Genferon is produced by the Russian biotechnology company Biocad in accordance with international standards(GMP), which is a guarantee of effective and safe treatment.

The amino acid taurine increases the biological effect of interferon due to its antioxidant properties and at the same time ensures the regeneration of damaged tissues.

Candles Genferon can be used both rectally and vaginally. Absorption and concentration of the drug in the pelvic organs are somewhat different in these cases. With vaginal, the local effect is more pronounced, and with rectal - systemic. The rectal and vaginal method of administration allows you not to stop the course of treatment during menstruation. The doctor, having familiarized himself with your disease, prescribes the most optimal treatment regimen.

Genferon candles: Instructions for use

Composition and form of release

Candles Genferon(vaginal / rectal suppositories) from white to white with a yellowish tint, cylindrical shape with a pointed end.

1 suppository contains:

Active ingredients: interferon human recombinant alpha-2a - 250,000 IU, 500,000 IU or 1,000,000 IU, as well as taurine 0.01 g and anesthesin 0.055 g;

Excipients:"hard fat", dextran 60000, polyethylene oxide 1500, tween 80, emulsifier T 2, sodium citrate, citric acid, purified water - enough to obtain a suppository weighing 1.65 g;

Package: packaging - 5 or 10 pcs. packaged.

Children's candles Genferon Light. Suppositories are inserted into the vagina or rectum. Available in two dosages - 125,000 IU and 250,000 IU in one candle, which are often briefly referred to as: Genferon 125 or Genferon 250.

pharmachologic effect

Genferon combination drug, the action of which is due to its constituent components. Provides local and systemic action.

Interferon alpha-2 has antiviral, antibacterial and immunomodulatory effects. Under the influence of interferon alpha-2 in the body, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, increases. The activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and ensures the restoration of the production of secretory immunoglobulin A.

Interferon alpha-2 also directly inhibits the replication and transcription of viruses, chlamydia. Taurine, which is part of the preparation, has regenerating, reparative, membrane- and hepatoprotective, antioxidant, anti-inflammatory properties.

Anestezin is local anesthetic. Reduces the permeability of the cell membrane for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, blocks conduction nerve impulses. Prevents the occurrence of pain impulses in the endings of sensory nerves and their conduction along the nerve fibers.

Pharmacokinetics

When administered vaginally or rectally, interferon alfa-2 is absorbed through the mucous membrane, enters the surrounding tissues, into the lymphatic system, providing a systemic effect. Also, due to partial fixation on the cells of the mucous membrane, it has a local effect.

A decrease in the level of serum interferon 12 hours after the administration of GENFERON necessitates its reintroduction.

Indications for use

Genferon is used as part of the complex therapy of infectious and inflammatory diseases of the urogenital tract:

• genital herpes
• chlamydia
• ureaplasmosis
• mycoplasmosis
• recurrent vaginal candidiasis
• gardnerellosis
• trichomoniasis;
• papillomavirus infection
• bacterial vaginosis
• cervical erosion
• cervicitis
• vulvovaginitis
• bartholinitis
• adnexitis
• prostatitis
• urethritis
• balanitis
• balanoposthitis

Dosage and administration

In infectious and inflammatory diseases of the urogenital tract in women. 1 suppository (250,000 IU or 500,000 IU, depending on the severity of the disease) vaginally 2 times a day, daily for 10 days. With protracted forms 3 times a week every other day, 1 suppository for 1-3 months.

In infectious and inflammatory diseases in men. Rectally 1 suppository (500,000 IU or 1,000,000 IU, depending on the severity of the disease) 2 times a day for 10 days.

A decrease in the level of serum interferon 12 hours after the administration of Genferon necessitates its repeated administration during the day.

Genferon Light for children

The drug, depending on the age of the child, is prescribed in different dosages.

Children from 1 to 7 years old only on the recommendation of a pediatrician the drug Genferon light is prescribed at a dosage of 125,000 IU.

Children from 7 to 14 years old can use suppositories at a dosage of 250,000 IU.

Teenagers over 14 years old medicinal product is prescribed depending on the severity of the disease at a dosage of 250,000 IU, 500,000 IU or 1,000,000 IU.

Candles are inserted into the rectum, that is, rectally. During treatment viral diseases it is recommended to administer one suppository twice a day for 5 days.

For chronic or protracted illness the course can be extended up to 10 days. It is recommended to ensure that the time interval between the introduction of candles does not exceed 12 hours.

In order to prevent viral infections and strengthening the child's own immunity for 1-3 months, a course of Genferon is prescribed - one suppository at night once every 2 days.

For the treatment of diseases of the genital organs and urinary system in children, a ten-day course is carried out - one candle twice a day.

The drug is used in complex therapy in combination with other drugs prescribed by a doctor (vitamins, antibiotics, etc.).

Candles for children Genferon rarely cause side effects. Most often, against the background of taking medications, they develop allergic reactions, which, as a rule, disappear on their own 3 days after discontinuation of the drug.

However, if such reactions occur, it is still better to consult a doctor or reduce the dosage of the drug.

special instructions

Genferon should be used with caution in patients with allergic and autoimmune diseases in the exacerbation phase.

Genferon is most effective in combination with drugs, including antibiotics and other antimicrobials, used to treat urogenital diseases.

Contraindications

Individual intolerance to interferon and other substances that make up the drug.

Pregnancy and lactation

It is shown to be used to normalize local immunity at 13-40 weeks of gestation as part of the complex therapy of genital herpes, chlamydia, ureaplasmosis, mycoplasmosis, CMV, human papillomavirus infection, bacterial vaginosis in the presence of itching, discomfort and pain in the area of lower divisions urogenital tract. The safety of the drug in the first trimester of pregnancy has not been studied.

Genferon is contraindicated in breastfeeding.

Side effects

Allergic reactions such as skin rashes and itching. These phenomena are reversible and disappear 72 hours after cessation of administration or dose reduction.

There may also be phenomena that occur with the use of all types of interferon alfa-2, such as chills, fever, fatigue, loss of appetite, muscle and headaches, joint pain, sweating, as well as leuko- and thrombocytopenia, but they are more common. with a dose of more than 10 million IU daily.

drug interaction

Genferon is most effective in combination with drugs (including antibiotics and other antimicrobials) used to treat urogenital diseases. It is recommended to simultaneously use vitamins E and C, which enhance the effect of interferon. Non-narcotic analgesics and anticholinesterase drugs enhance the action of anesthesin. Anestezin reduces the antibacterial activity of sulfonamides.

Analogues of Genferon

Active ingredient analogs

Genferon analogues according to active component does not exist.

Action analogues

• Altevir
• Alfarona
• Alfaferon
• Wellferon
• Grippferon
• Interferal
• Interferon alfa-2
• Intron A
• Inferon
• Lifeferon
• Lokferon
• Oftalmoferon
• Realdiron
• Reaferon-ES

Genferon reviews

Found HPV. The doctor prescribed treatment, but did not say anything about the seriousness of the disease. When I read on the Internet what it is, I was horrified. I went to the doctor again yesterday, the geneferon did not help me, but I hoped so. They prescribed it to me again, only now together with Indinol, I hope this treatment will be more effective.

Genferon used to buy for a child in the form of rectal suppositories. This time, when they picked up SARS, the pediatrician recommended buying a regular spray instead of candles. One dose of spray Genferon Light contains interferon alpha 2-b 50,000 IU. That is, if earlier we used candles with a dosage of 250,000 IU for our daughter, in one candle once a day, then everything is much simpler with a spray. I spray twice a day and three times in the evening in the nasal passage of a child. Very comfortably. It has immunomodulatory properties. From contraindications - childhood up to 14 years, hypersensitivity. But our pediatrician said that for our age of 2 years it can be used.

Genferon met with candles when his son was six months old. He fell ill with SARS for the first time, and our pediatrician prescribed these suppositories in combination with other medicines. The baby was ill for 7 days. When the son fell ill the next time (he was already almost 9 months old), the doctor prescribed exactly the same treatment. This time I didn't light candles. And the child recovered within a week. My familiar mothers also did not notice any effect from this drug. I didn't buy it again.

Genferon was powerless against HPV. A year ago, I was diagnosed with HPV type 16, I was treated, but the tests did not get better. After that, I drank Indinol as prescribed by the doctor. I re-tested and found nothing.

My daughter got sick for the first time at 8 months. Pediatrician prescribed antiviral suppositories Genferon. They helped us, but the runny nose still remained. Since they are small, they are very comfortable for the child. The only inconvenience, in terms of use, which I overlooked, must be stored in the refrigerator, otherwise they will deteriorate. All in all, excellent tool for the treatment of children, does not give side effects. At least for my child.

Good afternoon! Six months ago, I was diagnosed with the human papillomavirus by PCR analysis (I was examined for another reason, so I didn’t give special significance this diagnosis). And very in vain, because problems have recently appeared: papillomas have formed at the entrance to the vagina. I immediately went to the doctor, she confirmed my presumptive diagnosis. They found HPV, there is only one treatment, everything needs to be removed with a laser. And yet, be sure to drink Indinol. He goes against the virus. I will be treated, I see these capsules help many. I don't think this is a coincidence.

We were prescribed these suppositories when the baby fell ill at 4 months. But to be honest, I special effect didn't notice from them. In general, I think that it is better to strengthen the child's immunity naturally, with the help of hardening, for example.

My daughter is 1 year 11 months old. We cheer 3 times. The first time they prescribed these candles. I didn't buy. The second time I decided to try, they helped us. The next day, my daughter began to feel better, and now she got sick again. I immediately bought these candles, and for 3 days my daughter is almost healthy. They help us a lot.

Genferon (interferon human recombinant alpha-2 + taurine_benzocaine) is a complex immunomodulatory drug endowed with an antiviral effect. Interferons are biologically active proteins that are formed in the cell in response to the invasion of viruses, exposure to allergens or mutagens. To date, biotechnology is considered one of the most advanced technologies for obtaining interferon preparations. It does not involve the use human blood as a raw material, which means that there is no need to decontaminate the synthesized drugs. The Russian biotechnology company "Biocad" created the drug Genferon in the form of vaginal and rectal suppositories. This drug is now widely in demand in complex treatment infectious and inflammatory diseases of the urogenital tract, including infections caused by trichomonas, chlamydia, mycoplasmas, ureaplasmas, genital herpes, vaginal candidiasis, bacterial vulvovaginitis, genital warts. The key component of Genferon is interferon-alpha 2b, which has a complex antiviral, antimicrobial, cytostatic and immunomodulatory effect. It is activated even before the immune mechanisms are activated, acting as the first line of defense against invading pathogens. Interferon realizes its action indirectly through two enzymes synthesized with its participation, one of which cleaves viral RNA, the other inhibits the formation of new viral proteins.

As a result, the number of viral particles is reduced by several orders of magnitude. But interferon is valuable not only for its antiviral effect: it is also active against Staphylococcus aureus, toxoplasma, chlamydia, legionella, cryptococcus, yeast. Another important component The interferon is taurine. This amino acid has the ability to restore the structure of affected tissues, which is ensured by its immunomodulatory, antioxidant, membrane-stabilizing and osmoregulatory properties. Taurine neutralizes the destructive effect free radicals, massively formed in the focus of inflammation, which prevents further destruction cell membranes and damage to cell DNA. The anti-inflammatory properties of taurine contribute to the rapid epithelialization and repair of tissues in the area of ​​inflammation. This amino acid has the ability to potentiate immune responses by activating the proliferation of cells that carry out the immune response. The third component of Genferon is the anesthetic benzocaine, whose task is fast elimination discomfort (itching, burning, etc.) with the introduction of a suppository. The combination of the neuromodulatory effect of taurine with the analgesic properties of benzocaine ensures that the quality of life of patients taking Genferon is maintained at a consistently high level.

Pharmacology

Combined drug, the action of which is due to the components that make up its composition. It has a local and systemic immunomodulatory effect.

Interferon alpha-2 has antiviral, antimicrobial and immunomodulatory effects. Under the influence of interferon alpha-2, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, increases. The activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and the restoration of the production of secretory immunoglobulin A.

Interferon alpha-2 also directly inhibits the replication and transcription of viruses, chlamydia.

Taurine has membrane and hepatoprotective, antioxidant and anti-inflammatory properties, enhances tissue regeneration.

Benzocaine is a local anesthetic. Reduces the permeability of cell membranes for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, blocks the conduction of nerve impulses. Prevents the occurrence of pain impulses in the endings of sensory nerves and their conduction along the nerve fibers.

Pharmacokinetics

When administered vaginally or rectally, interferon alfa-2 is absorbed through the mucous membrane, enters the surrounding tissues, into the lymphatic system, providing a systemic effect. Also, due to partial fixation on the cells of the mucous membrane, it has a local effect.

A decrease in the level of serum interferon 12 hours after the administration of the drug necessitates its repeated administration.

Release form

Suppositories from white to white with a yellowish tint, cylindrical shape with a pointed end.

Excipients: solid fat, dextran 60,000, polyethylene oxide 1500, tween-80, T2 emulsifier, sodium citrate, lemon acid, purified water.

5 pieces. - cellular contour packings (1) - packs of cardboard.
5 pieces. - cellular contour packings (2) - packs of cardboard.

Dosage

In infectious and inflammatory diseases of the urogenital tract in women, the drug is prescribed intravaginally, 1 supp. (250 thousand or 500 thousand IU, depending on the severity of the disease) 2 times / day for 10 days. At chronic diseases the drug is prescribed 3 times a week (every other day), 1 supp. within 1-3 months.

In infectious and inflammatory diseases of the urogenital tract in men, the drug is prescribed rectally, 1 supp. (500 thousand-1 million IU, depending on the severity of the disease) 2 times / day for 10 days.

Overdose

Interaction

When combined with antibiotics and other antimicrobials used to treat urogenital infections, the effectiveness of Genferon increases.

With simultaneous use with vitamins E and C, the effect of interferon is enhanced.

When combined with NSAIDs and anticholinesterase drugs, the action of benzocaine is potentiated.

When used together, the antibacterial activity of sulfonamides decreases (due to the action of benzocaine).

Side effects

Allergic reactions: skin rash, itching. These phenomena are reversible and disappear 72 hours after dose reduction or drug withdrawal.

With the introduction of the drug at a dose of 10 million IU / day, the risk of developing the following side effects increases.

From the side of the central nervous system: headache.

From the hematopoietic system: leukopenia, thrombocytopenia.

Other: fever, increased sweating, fatigue, myalgia, loss of appetite, arthralgia.

Indications

As part of complex therapy for infectious and inflammatory diseases of the urogenital tract:

• genital herpes;
• chlamydia;
• ureaplasmosis;
• mycoplasmosis;
• recurrent vaginal candidiasis;
• gardnerellosis;
• trichomoniasis;
• papillomavirus infections;
• bacterial vaginosis;
• erosion of the cervix;
• cervicitis;
• vulvovaginitis;
• bartholinitis;
• adnexitis;
• prostatitis;
• urethritis;
• balanitis;
• balanoposthitis.

Contraindications

Hypersensitivity to the components of the drug.

Application features

Use during pregnancy and lactation

special instructions