Side effects of famotidine. Disorders of the hematopoietic system. Visitor report on expiration date

Diseases of the digestive system tend to disrupt the normal functioning of all internal organs. For the correct appointment of treatment, an examination and consultation with a doctor is required.

Widely used to relieve symptoms of diseases digestive tract Famotidine, the instructions for use of which contain detailed recommendations for various occasions applications.

Form and composition

The drug Famotidine for the elimination of diseases of the digestive organs is available in the form of biconvex tablets. The tool has two types of dosage: 20 mg (brown shell) and 40 mg (pink shell) of the active substance.

The required type of dosage is selected individually for each patient.

Ingredients of the medicinal product:

The medicinal substance is located in 10 pieces on a special plate, there may be 2 or three plates in the package, depending on required amount drug.

pharmachologic effect

1. The medicinal substance Famotidine is aimed at reducing inflammatory formation in the digestive organs.
2. Famotidine belongs to the group of substances that reduce the secretion of glands in the stomach and prevents the development ulcerative lesions mucous membranes.
3. Reduces activity of hydrochloric acid, enhances the natural protective functions of the mucous membrane.
4. When applied, it increases the secretion of gastric mucus, which stops bleeding and reduces unpleasant symptoms.
5. Supports normal work digestive organs, reduces the likelihood of deposition of toxins and toxins.

Pharmacokinetics

1. After application, the tablet quickly dissolves in the stomach and is absorbed by the mucous membranes.
2. Most high level Famotidine action occurs 3 hours after application.
3. Partially excreted after 5 hours with the help of the kidneys and liver.
4. Does not affect the functioning of other organs correct application normalizes acidity - alkaline level in the stomach.
5. It tends to color urine yellow when excreted.

Pharmacodynamics

1. Active ingredient famotidine reduces Negative influence hydrochloric acid and has protective functions in places of damage to the gastric mucosa.
2. Reduces the level of pepsin in the digestive organs, triggers natural processes regeneration of damaged cells.
3. Has the ability to penetrate soft tissues person, including breast milk.
4. The result after applying the substance lasts from 6 to 10 hours, depending on individual features organism.

Indications for use

The substance Famotidine requires compliance with strict instructions for use and is prescribed for the following situations:

Treatment with this remedy requires compliance with the rules for observing a special type of diet, which enhances the result from the use of Famotidine.

Contraindications

• individual intolerance to the constituent components
• pregnancy
• lactation
• age up to 12 years
• kidney disease
• cirrhosis of the liver
• age over 60

It is forbidden to use Famotidine during a period when there is a sharp decrease in human immunity.

Dosing method

The medicinal substance is used twice a day, the tablet is swallowed whole and washed down large quantity clean water.

The course of treatment is prescribed individually, but the following approximate dosages are available:

• ulcer of the digestive organs- applied twice a day for 5 weeks;
• increased secretion of the digestive organs- Apply once a day at bedtime. The course of treatment is prescribed individually;
• Soliten-Ellison disease- the substance is applied every 6 - 7 hours, one tablet of 20 mg., The course of application depends on the severity of the disease;
• prevention of ulcerative lesions of the digestive organs- applied once a day for 2 weeks;
• bleeding- given twice a day complex therapy, course no more than 3 weeks;
• aspiration gastric juice - applied twice a day for 7 weeks;
• to normalize acid – alkaline balance applied once at bedtime for 14 days.

Use in children

Famotidine is not allowed to be used for children under 12 years of age, otherwise there may be side effects that pose a threat normal functioning internal organs.

Use during pregnancy and lactation

Famotidine is contraindicated during gestation and breastfeeding child. Active components tend to cross the placenta and disrupt the development of the kidneys of the fetus. There is also a property to be transmitted with breast milk. If treatment is necessary, the child is recommended to be transferred to artificial feeding.

Use in violation of the functioning of the liver and kidneys

If the patient has a decrease in the functioning of the kidneys and liver, the drug is prescribed in a reduced dosage. Since the withdrawal time of substances increases to 15 hours and can cause an overdose.

Stories from our readers!
“From childhood, I had stomach problems, pancreatitis, periodic inflammation of the pancreas. I tried to monitor my diet, I was regularly observed by the doctor. But this did not save me from gastritis. There was heaviness in the stomach when I ate something sour, heartburn occurred.

I bought a propolis elixir, I liked the composition, and in all forums about self-treatment you will always find propolis. I started drinking and after a few weeks the disease subsided. Now I know what can help in the fight against the signs of gastritis, I will have propolis tincture in my first aid kit!"

drug interaction

Not applicable with alcoholic drinks, may contribute to the formation of poisoning.

Side effects

Famotidine tends to cause unpleasant side effects:

1. From the side nervous system - dizziness, hallucinations, depression.
2. From the digestive organs- Nausea, vomiting, stomach pain, lack of appetite.
3. From the side of the work of the cardiac organs and circulatory system - tachycardia, violation of pressure, the formation of blood clots in the blood vessels;
4. From the side reproductive system - Violation of impotence, lack of libido.
5. allergic reactions, which may appear varying degrees skin rashes.

AT rare cases blurred vision and fever may be observed.

special instructions

To increase the effectiveness of the use of the drug Famotidine, the following special instructions must be observed:

• use the substance only for its intended purpose for the treatment of diseases of the digestive organs;
• a disease of the digestive organs is associated with other types of damage to the internal organs;
• if after treatment the patient loses body weight, it is recommended to stop treatment;
• treatment is recommended to be carried out strictly under the supervision of the attending physician;
• in the absence of timely use of the drug, it is forbidden to double the dosage;

As part of medicinal substance lactose is present, so the patient should be warned before starting treatment. To reduce the likelihood of allergic reactions.

Overdose

Medical experts say that compliance with the recommended dosage of the substance rarely causes an overdose.

However, there may be the following symptoms with improper use of Famotidine:

• vomit
• sharp pain in the stomach
• loss of consciousness
• pressure reduction

If such symptoms appear, it is necessary to rinse the stomach with boiled water, contact the nearest medical facility.

Storage conditions

Famotidine is stored in a place away from children without direct penetration sunlight. Shelf life is not more than 4 years from the date marked on the package.

The price of the drug

You can buy the drug Famotidine at any pharmacy by providing a prescription from your doctor.

1. You can buy the drug at a price 45 - 60 rubles for a pack of tablets with 20 mg of the active ingredient, the price depends on the number of plates.
2. If necessary increased dosage cost varies from 65 to 90 rubles for tablets with 40 mg of the active substance.

Analogues

When showing any side effects when using the drug Famotidine, you can use drugs similar action prescribed by the attending physician.

The following analogues are most often used:

1. Gastrocidin- the active component of the substance famotidine is used to treat diseases of the digestive organs. It is an analogue of the drug substance Famotidine. Released strictly according to the prescription. average cost 130 rubles.
2. gistak- a drug in the form of tablets that eliminate the formation of ulcerative lesions and have a restorative property. Contraindicated for children under 18 years of age. The drug has a strong effect and can contribute to the occurrence of a large number of side effects. Price 50 rubles.
3. Ranitidine- the tool has increased level absorption and quickly eliminates unpleasant symptoms in the gastrointestinal tract. At misuse can contribute to the formation of a large number of side effects. average cost 40 rubles.
4. Atsilok- affects the digestive organs in a similar way as the substance Famotidine. However, it tends to be better tolerated by the body and cause fewer adverse reactions. The drug is prescribed by a doctor, released strictly by prescription. Price 250 rubles.
5. Cimetidine- is prescribed for the treatment of digestive organs. In complex types of the disease can be used for intramuscular injection. Rarely used for complex treatment. If it is necessary to use additional medicines, it is necessary to study the constituent components in detail. Promotes the formation of side effects when used with alcoholic beverages. Price 260 rubles.
6. Zantac- a preparation for the preparation of a solution for oral administration. Not recommended for use with other similar substances. Price 220 rubles.
7. Kvamatel- the substance is used to increase protective functions stomach and reduce the production of excessive amounts of gastric juice. It is prescribed for the treatment of many diseases of the digestive tract. Price 140 rubles.

Each of the drugs similar in their action to Famotidine can affect the state of health in different ways and is not suitable for every patient. Therefore, before using any remedy, it is recommended that you carefully study the instructions for contraindications and possible adverse reactions.

Conclusion

The drug Famotidine has overall impact on the digestive organs and starts the natural processes of restoring damaged areas. The active ingredient famotidine has a deep level of penetration and eliminates a large number of various diseases.

Experts recommend during the period of treatment with Famotidine to observe special kind diet food, the action of which is directed to the elimination of the use harmful products, and facilitating the digestion of food by the stomach. The method of nutrition is prescribed by the doctor for each patient individually.

Patients who are diagnosed with an ulcer are well aware of how painful, unpleasant, and sometimes very painful manifestations of this pathology. It is not surprising that such a category of people, as a rule, does not resort to self-treatment. They trust their health in the hands of doctors. After all, doctors select enough effective therapy that can quickly relieve symptoms. One of the drugs that is often recommended to patients is the drug "Famotidine". We will study in more detail the indications for the use of this remedy, the prescribed dosages and the established contraindications.

a brief description of

The drug "Famotidine" belongs to a group of drugs that are called "histamine H2 receptor antagonists." The drug is used in the treatment of peptic ulcers. Included in the therapy of reflux esophagitis.

The tool perfectly prevents the production of hydrochloric acid. Provides a decrease in the activity of pepsin - the enzyme that breaks down proteins. It is on these properties that the indications for use of the drug "Famotidine" are based. Patient reviews indicate that healing effect manifests itself 45-60 minutes after taking the first dose. The beneficial effect may last for about 12-24 hours.

The drug is produced in the form of tablets. active substance pill is famotidine. Depending on its content, tablets are produced, which include 0.02 g of the main component and 0.04 g.

Consider the pathologies under which the medication "Famotidine" is justified.

Indications for use

The medicine is prescribed, as mentioned above, for peptic ulcers. However, it is advisable to take it in preventive purposes. To avoid the development of peptic ulcer, doctors recommend using this remedy patients long time who are on NSAID therapy and glucocorticosteroids. Also, with many other pathologies, the drug "Famotidine" is prescribed.

Indications for the use of the drug:

1. Ulcers of the stomach, duodenal ulcers, including prevention of recurrence.
2. Reflux esophagitis.
3. associated with increased secretory function.
4. Stress, symptomatic ulcers.
5. Erosive gastroduodenitis.
6. Systemic mastocytosis.
7. Prevention in postoperative period recurrence of bleeding.
8. Zollinger-Ellison syndrome.
9. Polyendocrine adenomatosis.
10. Prevention of aspiration in patients with gastric juice, during surgery under general anesthesia (with
11. Prevention of aspiration pneumonitis.
12. Dyspepsia with retrosternal or epigastric pains that appear at night or are associated with eating.

Medication dosages

Each patient is selected a treatment regimen purely individually. Therefore, it is important to visit a doctor and go through all necessary diagnostics so that the doctor can prescribe the most effective treatment. It is highly undesirable to take the drug "Famotidine" on your own.

1. Gastrointestinal ulcers in the acute stage, symptomatic ulcers. The medicine is prescribed to be taken twice a day for 20 mg. Sometimes it is recommended to use a tablet only at night, but at a dosage of 40 mg. If it is not possible to achieve the desired effect, then the doctor may recommend taking 80-160 mg for 1 day. Treatment continues for 4 to 8 weeks.
2. Dyspepsia. In this case, it is advisable to take 1 tablet (20 mg) 1-2 times a day.
3. Prevention of peptic ulcers. Once a day, before going to bed, appoint 20 mg.
4. Reflux esophagitis. For 6-12 weeks, twice a day, 20-40 mg.
5. Zollinger-Ellison syndrome. The initial dose is 20 mg. It is recommended to take a tablet every 6 hours. In some situations, a single dose may be increased to 160 mg.

Sometimes the medicine is prescribed for children older than 3 years. However, the body weight of such patients should be more than 10 kg. With an exacerbation peptic ulcer or reflux esophagitis must be calculated daily allowance for the baby. Recommended at 2 mg/kg. It is divided into 2 uses per day. However, the maximum daily intake is 40 mg.

Contraindications

The drug does not contain many restrictions. This distinguishes the drug from most other drugs.

The main contraindications to taking pills are:

• pregnancy;
• childhood;
• lactation period;
• individual sensitivity.

Be sure to consult with your doctor before using this remedy about the appropriateness of therapy with this remedy and the required dosage.

If the patient has renal insufficiency, the regimen is prescribed individually. As a rule, the doctor recommends reducing the doses taken.

Side effects

Undesirable manifestations lead to a lot of the drug "Famotidine" instructions for use. Description side effects extremely rare in patient reviews. But let's take a look at them anyway.

According to the instructions, the patient may experience the following symptoms:

1. Appetite disturbance.
2. Abdominal pain, nausea, vomiting, diarrhea, flatulence, constipation.
3. Increased activity of liver enzymes, acute pancreatitis, hepatitis.
4. Dry mouth.
5. Headache, insomnia, anxiety, dizziness, tinnitus.
6. Fuzzy visual perception, paresis of accommodation.
7. Hyperthermia, fever.
8. sleepiness, depression, fatigue, nervousness, psychosis.
9. Confusion of consciousness, hallucinations.
10. Bradycardia, arrhythmia, hypotension, vasculitis, AV block.
11. Muscle pain, joint discomfort.
12. Skin rash, alopecia, dry skin, itching, angioedema, acne vulgaris, bronchospasm, anaphylactic shock, various manifestations of hypersensitivity.
13. agranulocytosis, pancytopenia, bone marrow aplasia, hypoplasia, leukopenia, thrombocytopenia.
14. Hyperprolactinemia, gynecomastia, impotence, amenorrhea in case of long-term therapy at high dosages.

special instructions

It is important to take into account not only the drug "Famotidine" indications for use. The medicine has some features.

The instruction warns of the following properties of tablets:

1. Before starting therapy with this medicine, it is necessary to exclude such a pathology as malignant disease GIT. The drug "Famotidine" is able to mask the symptoms, as a result of which timely diagnosis is difficult.
2. Painful manifestations of ulcerative ailments often disappear after 1-2 weeks of taking the medication. However, the patient must drink full course prescribed by a doctor. Stop therapy only after scarring of the ulcer, which is confirmed by X-ray or endoscopic examination.
3. When the drug is discontinued, the patient is prescribed a gradual dose reduction. Abrupt rejection from the drug leads to the "rebound" syndrome.
4. During therapy, you should follow healthy diet. It is recommended to avoid food that provokes irritation of the mucosa.
5. Smoking may reduce the effectiveness of the drug.
6. If a dose has been missed, it is recommended to drink it as soon as possible. But if it's your turn next appointment, then doubling the dose is strictly contraindicated.

Medicine analogs

Medicines that have the same active substance as the original remedy are medicines:

• "Gasterogen".
• "Gastrocidin".
• "Pepsidin".
• "Kvamatel".
• "Ulfamid".
• "Phamopsin".
• "Kvamatel mini".
• Famosan.
• Famotel.

Medication cost

However, patients choose this remedy not only for such numerous drugs "Famotidine" indications for use. The price is simply amazing, it is so low.

Depending on the dosage and number of tablets, the cost of the medication varies between 33-78 rubles.

Opinions about the drug

It is quite clear how the instruction positions the medicine "Famotidine". Application, patient reviews are of great interest. What do people who have been prescribed medication talk about?

Patients report that, having experienced many various medicines, opted for the drug "Famotidine". After all, the pills perfectly and very quickly eliminate unwanted symptoms. At the same time, patients note a mild effect on the body.

Patients claim that the drug is equally effective in ulcer pathologies, and with gastritis, and in the case of acute pancreatitis.

Thus, it can be concluded that it is quite reasonable to refer to effective drugs medicine "Famotidine" instruction. Application (reviews of people testify to this) means contributes quick release from distressing symptoms.

Pharmacodynamics

Reduces the activity of pepsin. Strengthens defense mechanisms gastric mucosa and promotes healing of its damage associated with exposure to hydrochloric acid (including the cessation of gastrointestinal bleeding and scarring of stress ulcers) by increasing the formation of gastric mucus, the content of glycoproteins in it, stimulating the secretion of bicarbonate by the gastric mucosa, endogenous synthesis in her prostaglandins and the rate of regeneration. Significantly does not change the concentration of gastrin in plasma. Weakly inhibits the cytochrome P450 oxidase system in the liver. After oral administration, the action begins after 1 hour, reaches a maximum within 3 hours. The duration of action of the drug in a single dose depends on the dose and ranges from 12 to 24 hours.

Pharmacokinetics

Bioavailability - 40-45%, increases when taken with food and decreases when taking antacids. Communication with plasma proteins - 15-20%. 30-35% of famotidine is metabolized in the liver (with the formation of S-oxide). Elimination mainly occurs through the kidneys: 27-40% of the drug is excreted in the urine unchanged.

The half-life is 2.5-4 hours; in patients with creatinine clearance below 30 ml / min, it increases to 10-12 hours. In patients with severe kidney failure(creatinine clearance below 10 ml/min) it increases up to 20 hours. Penetrates through the placental barrier and excreted in breast milk.

2. indications for use

• Famotidine should be taken when you have peptic ulcer of the duodenum and stomach in the acute phase, prevention of relapses.
• Treatment and prevention of symptomatic gastric and duodenal ulcers (associated with the use of non-steroidal anti-inflammatory drugs, stress, postoperative ulcers).
• Famotidine should be taken when you have erosive gastroduodenitis.
• Functional dyspepsia associated with increased secretory function of the stomach.
• Reflux esophagitis.
• Zollinger-Ellison syndrome.
• Prevention of rebleeding from upper divisions GIT.
• Prevention of aspiration of gastric juice general anesthesia(Mendelssohn's syndrome).

3. How to use

In order to prevent recurrence of peptic ulcer, 20 mg is prescribed once a day at bedtime.

With reflux esophagitis - 20-40 mg twice a day for 6-12 weeks.

With Zollinger-Ellison syndrome, the dose of the drug and the duration of the course of treatment are set individually. The initial dose is usually 20 mg every 6 hours and may be increased to 160 mg every 6 hours.

For the prevention of aspiration of gastric juice during general anesthesia, 40 mg is prescribed in the evening and / or in the morning before surgery. Famotidine tablets should be swallowed without chewing, drinking enough water.

In renal failure, if creatinine clearance is less than 30 ml / min or serum creatinine is more than 3 mg / 100 ml, daily dose the drug should be reduced to 20 mg.

4. Side effects

• From the side digestive system : dry mouth, nausea, vomiting, abdominal pain, constipation, diarrhea, loss of appetite, increased activity of "liver" transaminases, cholestatic jaundice, acute pancreatitis.
• From the side of the nervous system: headache, dizziness, asthenia, drowsiness, insomnia, fatigue, depression, agitation, tinnitus, hallucinations, confusion, blurred vision.
• From the side of cardio-vascular system : decrease blood pressure, bradycardia, atrioventricular block, arrhythmia, vasculitis.
• allergic reactions: skin rash, itching, urticaria, bronchospasm, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylactic shock.
• From the side of the hematopoietic organs: leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, hypoplasia, bone marrow aplasia.
• From the reproductive system: at long-term use large doses- hyperprolactinemia, gynecomastia, amenorrhea, decreased libido, reduced potency.
• Other: acne, alopecia, fever, arthralgia, myalgia.

5. Contraindications

Pregnancy, lactation, liver failure, childhood, hypersensitivity to the components of the drug. Lactose intolerance, lactase deficiency or glucose-galactase malabsorption.

6. During pregnancy and lactation

7. Interaction with other drugs

With simultaneous use with antacids, sucralfate, the intensity of famotidine absorption decreases, so the interval between taking these drugs should be at least 1-2 hours.

Increases the absorption of amoxicillin and clavulanic acid.

Drugs that depress Bone marrow increase the risk of developing neutropenia.

8. Overdose

Symptoms:

Treatment:

9. Release form

10. Storage conditions

Best before date

11. Composition

1 tablet 20 mg Famotidine contains:

1 tablet 40 mg contains:

12. Terms of dispensing from pharmacies

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*Instruction for medical use for Famotidine is published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST

Composition and form of release

in a blister pack 10 pcs.; in a pack of cardboard 2 or 3 blisters.

Description of the dosage form

20 mg tablets: round, biconvex film-coated tablets, pale brown.

40 mg tablets: round, biconvex film-coated tablets, reddish-brown color.

pharmachologic effect

Blocks histamine H 2 receptors, inhibits the production of hydrochloric acid.

Clinical pharmacology

The duration of action with a single dose is from 12 to 24 hours.

Indications for Famotidine

Peptic ulcer of the stomach and duodenum (including prevention of exacerbations); symptomatic ulcers, erosive and reflux esophagitis; Zollinger-Ellison syndrome.

Contraindications

Hypersensitivity, pregnancy, lactation.

Side effects

Rarely - headache, dizziness, fatigue, dry mouth, lack of appetite, diarrhea or constipation, skin rash.

Interaction

Dosage and administration

inside, swallowing whole (without chewing), washing down with a sufficient amount of water. With peptic ulcer of the stomach and duodenum in the acute phase, symptomatic ulcers, erosive gastroduodenitis - usually 20 mg 2 times a day or 40 mg 1 time per day at night. If necessary, the daily dose can be increased to 80-160 mg. The course of treatment is 4-8 weeks.

With dyspepsia associated with increased secretory function of the stomach - 20 mg 1-2 times a day.

In order to prevent recurrence of peptic ulcer - 20 mg 1 time per day at bedtime.

With reflux esophagitis - 20-40 mg 2 times a day for 6-12 weeks.

With Zollinger-Ellison syndrome, the dose of the drug and the duration of the course of treatment are set individually. The initial dose is usually 20 mg every 6 hours and may be increased to 160 mg every 6 hours.

For the prevention of aspiration of gastric juice during general anesthesia - 40 mg in the evening and / or in the morning before surgery.

With renal failure (with Cl creatinine<30 мл/мин или содержании креатинина в сыворотке крови >3 mg / 100 ml) the daily dose of the drug should be reduced to 20 mg.

Precautionary measures

Before treatment, it is necessary to exclude the presence malignant process in the gastrointestinal tract. Use with caution in patients with impaired liver and kidney function.

Storage conditions of the drug Famotidine

Keep out of the reach of children.

Shelf life of the drug Famotidine

Do not use after the expiry date stated on the packaging.

Instructions for medical use

Synonyms of nosological groups

Famotidine is a member of the group of histamine H2 receptor antagonists. The remedy is often used to treat reflux esophagitis and peptic ulcers of the stomach and duodenum. Provides effective reduction acidity of gastric juice. The drug has its own contraindications for use and can provoke the manifestation of adverse reactions from various organs and systems. The drug is not recommended for use during pregnancy and breastfeeding.

Dosage form

The drug Famotidine is produced by pharmacological companies in the form of tablets intended for oral administration.

Description and composition

Famotidine tablets have round shape, they are also distinguished by their biconvexity and a pale shade of pink-gray. On a break the tablet is white.

The composition of the product includes a number of substances, the main of which is famotidine at a dosage of 20 and 40 mg, depending on the form of release.

Auxiliary components include:

• corn starch;
• microcrystalline cellulose;
• silica;
• talc;
• magnesium stearate;
• croscarmellose sodium.

Compound film shell includes:

• hypromellose;
• titanium dioxide;
• lactose monohydrate;
• macrogol 4000;
• triacetin;
• yellow dye (E172);
• red dye (E172);
• black dye (E172).

Pharmacological group

The agent belongs to blockers of H2-histamine receptors of the III generation. Famotidine inhibits basal, as well as histamine-, acetylcholine- and gastrin-induced secretion of hydrochloric acid. The pH rises and the activity of pepsin falls. Significant changes in the content of gastrin in the blood serum are not observed. There is also a slight suppression of the cytochrome P450 oxidase system in the liver.

The onset of action of the drug occurs 60 minutes after ingestion, and after three hours the maximum is reached. The duration of the period of action when used once lasts from 12 to 24 hours.

After oral use medication there is rapid absorption from the gastrointestinal tract. The maximum concentration in the blood serum is observed within a period of 1.5 to 5 hours. Bioavailability averages 40-45%. Famotidine is able to penetrate the placental barrier, as well as enter breast milk. The ability to bind to blood proteins ranges from 15 to 20%.

From 30 to 35% is metabolized in the liver.

The drug is excreted mainly with the help of the kidneys, from 27 to 40% of the substance is excreted in the urine unchanged. The half-life reaches 2.5-4 hours.

Indications for use

The list of indications for taking the drug can be presented in the following form:

• stomach ulcer;
• erosive gastroduodenitis;
• reflux esophagitis;
• Zolinger-Ellison syndrome;
• prevention of the occurrence of complications in stomach ulcers;
• mastocytosis;
• dyspeptic syndrome.

for adults

The composition can be used by patients of this group if there are indications for use. Before you start using the composition, you should consult a doctor.

for kids

The tool can be used in pediatric practice. The composition is prescribed to children over the age of 3 years.

The period of pregnancy is a contraindication to the use of the drug.

Contraindications

The list of contraindications to the use of the composition can be presented as follows:

• children's age up to 3 years;
• pregnancy;
• breastfeeding period;
• hypersensitivity to the components of the drug.

Applications and doses

Famotidine tablets are taken orally, units of the drug must be washed down with a small but sufficient amount of clean water. The dosage regimen differs significantly for patients with different indications.

for adults

The defeat of the stomach ulcer and duodenal ulcer, erosive gastroduodenitis, symptomatic ulcer. Adult patients are prescribed 20 mg of the substance twice a day or 40 mg once a day at bedtime. It may be necessary to increase the dosage to 80-160 mg per day. The duration of the drug is from 4 to 8 weeks.

Dyspepsia associated with excessively active secretory function in the stomach and duodenum. With this pathology, it is recommended to use 1 tablet (20 mg) once or twice a day.

Prevention of recurrent peptic ulcers of the stomach and intestines. You need to take 20 mg (one unit of the drug) at bedtime.

Gastroesophageal reflux pathology. Adult patients with this disease are recommended to take 20-40 mg of the substance twice a day. The course of treatment is from 6 to 12 weeks.

Ulcerogenic adenoma of the pancreas. The mode of administration must be obtained from the attending specialist. In this case it is set individually. Usually the first dose is 20 mg every 6 hours and may then be increased to 160 mg every 6 hours. Preventive measures to combat aspiration of gastric juice in the context of general anesthesia Adults are prescribed the use of 40 mg of the drug in the evening or in the morning before the procedure. surgical procedure. The doctor may also consider it necessary to take both doses in the evening and in the morning, 40 mg each.

Preventive measures against recurrent bleeding from the upper gastrointestinal tract. The use of the drug is carried out twice a day for 20 mg. The duration of the course of therapy is from 3 to 4 weeks.

For patients with renal insufficiency, the dose may need to be reduced.

for kids

Children under 12 years of age are not prescribed this remedy. medicinal orientation. For older patients, the dosing regimen is similar to that prescribed for adult patients.

for pregnant women and during lactation

Side effects

Against the background of the use of the medicinal composition, the following adverse reactions may occur:

• loss of appetite;
• the appearance of dryness in the oral cavity;
• bad breath;
• a disorder of taste buds;
• the appearance of nausea;
• gagging;
• bloating;
• diarrhea;
• change in liver tests;
• headache;
• increased fatigue;
• noise in ears;
• mental disorders;
• arrhythmia;
• agrunolocytosis;
• pancytopenia;
• leukopenia;
• muscle pain;
• alopecia;
• acne;
• dry skin.

Interaction with other drugs

Taking Famotidine can cause a decrease in the absorption of ketoconazole and.

Co-administration with antacids, sucralfate reduces the absorption of famotidine. The interval between doses should be at least 2 hours.

Famotidine inhibits the hepatic metabolism of phenazole, diazelam, theophylline, glipizide, blockers calcium channels, aminophenazole, hexobarbital, phenytoin, indirect anticoagulant drugs, buformin, caffeine, tricyclic antidepressants.

- famous antiulcer drug, which is effective against common intestinal bacteria Helicobacter pylori. The tool has astringent action and affects all stages of the digestive chain. In most cases medicinal composition well tolerated by patients, but the risk of side effects is present. Dosages and duration of taking the drug are determined jointly with the attending physician in private. Reception during pregnancy and breastfeeding is possible in the presence of medical indications. The tool can be used in pediatrics.

Gaviscon

Gaviscon - medicine with enveloping effect. The composition after contact forms a special film in gastrointestinal tract. Produced by pharmaceutical companies in several dosage forms: suspension and chewable tablets. It should be noted that the effect of taking the suspension appears faster - 15-20 minutes after consumption and lasts for 8 hours. The agent is well tolerated by patients various categories. If there are medical indications, it can be used during pregnancy and breastfeeding in limited doses selected by a specialist. Data on the use of the composition in pediatrics are not available.

Ectis - complex tool, which has a mild effect on the human body. The composition is able to activate the process of the digestive chain. The disadvantage of the composition is a large number of contraindications. Data on the safety of the drug during pregnancy and breastfeeding are not available. The composition is forbidden to be used in pediatric practice, since its effect on children's body studied incompletely.

Gastromax

This medicine is a chewable tablet. In its composition, the drug has three active ingredients, one of which is famotidine, the others are magnesium hydroxide and calcium carbonate. The last two have a neutralizing effect on gastric acidity.

The active ingredient in this drug is. The tool also produces an antiulcer effect. Produced in tablet form. Indications for use generally coincide with the list of diseases for which Famotidine is prescribed.

Dicyclomine is also present in this drug-oriented drug among the active ingredients. The drug is used for the same indications as the previous two. Produced in the form of tablets.

Price

The cost of Famotidine averages 55 rubles. Prices range from 13 to 100 rubles.