Genferon 1000 suppositories instructions for use. Instructions for use of vaginal and rectal suppositories geneferon - composition, side effects and analogues

Interferons are substances that make the cells of the human body immune to viruses. Immediately after their discovery in the 20th century, preparations containing these biological molecules appeared. By adding vitamins, anti-inflammatory and other components to interferons, you can get effective remedies for many diseases. One of the brightest examples is "Genferon". The drug is active against a number of viruses, bacteria, fungal microorganisms. What does the instruction for the use of candles "Genferon" say, and is this medicine safe?

"Genferon" in pharmacies is sold as rectal and vaginal suppositories, there are various dosages. A nasal spray is also provided. The drug is well tolerated, its administration is almost never accompanied by side effects and gives a significant result. Reviews of candles "Genferon" confirm their effectiveness.

Compound

The main effect of the drug is due to the human interferon alpha 2b that is part of the drug. Suppositories are available in the following dosage:

• 125 thousand IU;
• 250 thousand IU;
• 500 thousand IU;
• 1 million IU.

In addition to interferon, each suppository contains the following components:

• amino acid - taurine in the amount of 0.01 g;
• analgesic component- benzocaine or anesthesin in the amount of 0.055 g.

There is no anesthetic ingredient in children's candles from the Light series. As forming components, all suppositories include macrogol, polysorbate, emulsifiers, sodium hydrocitrate, citric acid, dextran, water and solid fat.

Operating principle

Rectal use of suppositories is comparable in terms of the speed of the effect and the subsequent concentration of the active substance in the bloodstream with injections. The rich network of blood vessels of the rectum and the special structure of the mucosa allow the drug to be rapidly absorbed. "Genferon" is metabolized in the liver and kidneys, therefore, these organs play a role in the excretion of the drug. Within 12 hours after the introduction of the suppository, the concentration of the active substance in the blood drops by half, so the regimens include the use of suppositories twice a day.

With vaginal application, one fraction of the substance enters the systemic circulation, the rest acts locally. Therefore, in case of gynecological diseases, it is better to use a “targeted” delivery of the drug to the focus, and if it is necessary to increase the systemic antiviral response, it is necessary to use the rectal route of administration.

Candles must be stored at a temperature not exceeding +4 ° C to prevent the destruction of interferon.

Interferon

Human interferon is produced by special types of Escherichia coli, which have introduced the genes responsible for the production of this biologically active substance. Interferon is able to cause the following actions:

• antiviral- stops the reproduction of viral particles by deactivating special enzymes and disrupting the interaction of pathogens with human cells;
• antibacterial- activates the links of immunity responsible for the destruction of pathogenic bacteria;
• immunomodulatory- increases the activity of T-helpers (types of lymphocytes) of B-lymphocytes, macrophages, as a result, the immune system recognizes pathogens faster, inactivates them and creates memory cells (immunity);
• antiproliferative- the drug is able to stop the division of viral cells, as well as chlamydia, ureaplasmas and mycoplasmas, therefore, it is prescribed in the complex treatment of these infections.

Amino acid

Taurine has a general stimulating effect on the body, and also increases the activity of interferon, being a trigger in the composition of the drug "Genferon". Namely, there are the following effects:

• improves metabolism;
• increases the ability of cells to self-repair;
• increases the resistance of tissues to viruses and bacteria;
• there is a neutralization of harmful metabolic products - free radicals.

Pain Relieving Component

Benzocaine and anesthesin act locally, blocking the conduction of nerve impulses through the tissues. This achieves an analgesic effect, reducing the intensity of burning, itching, which is important in the treatment of gynecological diseases.

When is it useful to use

"Genferon" can be used for any diseases, if their viral or bacterial nature is assumed. Candles "Genferon light" are more often used for children due to the lower dose of the drug and the absence of an anesthetic in the composition. Use cases are as follows:

• rotavirus;
• SARS and influenza;
• at a temperature during teething;
• chickenpox.

The use of candles "Genferon" in gynecology includes the following list of pathologies:

• STIs - chlamydia, ureaplasmosis, mycoplasmosis, trichomoniasis, herpes, human papillomavirus (especially with HPV types 16 and 18);
• nonspecific inflammation- vaginitis, cervical erosion, adnexitis;
• recurrent thrush- for the treatment and prevention of new episodes of the disease;
• disruption of the vaginal flora- bacterial vaginosis (gardnerellosis).

The drug is prescribed in treatment regimens for dysplasia, especially with signs of viral damage, as well as endometriosis. It is effective to use "Genferon" in the treatment of cystitis, urethritis, and prostatitis in men. The agent is used in the treatment of hepatitis, cytomegalovirus infection, including during pregnancy.

To whom the drug is contraindicated

Candles "Genferon" should not be used in case of hypersensitivity to any component of the drug, as well as in case of ever recorded allergy to analogue drugs. From rectal use, it is necessary to refrain from exacerbation of hemorrhoids.

Contraindications for use are autoimmune diseases, since the drug can compromise the exacerbation or progression of ailments. For example, with autoimmune thyroiditis, glomerulonephritis, diabetes mellitus, scleroderma.

"Genferon" during pregnancy is allowed only from 12 weeks according to indications. Data on the safety of use is not previously available. For the time of use during lactation, it is recommended to stop breastfeeding.

Instructions for use "Genferon"

Depending on the purpose of therapy, the methods of using the drug also differ somewhat. The main points in the treatment of women are as follows:

• standard scheme- one suppository in the vagina twice a day for ten days (for gynecological diseases and genital infections);
• evening candle - if necessary (if there are other suppositories), you can lay it rectally;
• with recurrent processes- after the main treatment, it is necessary to lay one candle for three months;
• in diseases not related to the genital organs- suppositories should be inserted rectally;
• during menstruation– should be switched to rectal use.

Men and children should use one suppository in the rectum in the morning and evening.

Nasal spray "Genferon" is used in men, women and children after 7 years - twice a day, one injection for the prevention and treatment of colds.

Admission complications

Side effects of "Genferon" do not differ in frequency of manifestation - usually candles and spray are well tolerated. The following symptoms are rarely seen:

• headache;
• increased fatigue;
• weakness in muscles and joints;
• loss of appetite;
• increased sweating;
• locally - itching, burning, increased secretions;
• fever on the first day of admission.

If a side effect is suspected, these symptoms should first be excluded as manifestations of the underlying disease. Reviews of doctors indicate a good tolerability of the drug when administered to patients. Cases of overdose have not been identified.

Analogues

Among the analogues of the drug for the main active substance, interferon, the following drugs can be distinguished:

• "Viferon";
• "Interferon";
• "Kipferon";
• "Laverobion".

"Genferon" - a drug with antiviral, antibacterial activity, stimulates the immune system and helps fight infection. But the indications for the use of "Genferon" are determined only by the doctor, as well as the schemes, as well as the duration of treatment.

The drug Genferon is an antimicrobial agent. It helps to cure the inflammatory processes of the human urogenital organs. This drug is active against many microorganisms of a viral, fungal and bacterial origin.

The immunomodulatory effect is aimed at enhancing the immune response, which allows you to successfully fight microbes that cause chronic inflammation in humans.

Description

The drug is made in the form of small suppositories (suppositories) that are inserted into the rectum or vagina. The shape of the candles is similar to an oval, one edge of which is slightly pointed. Suppositories produce a white or pale yellowish color. They have a uniform structure on the inner surface. Packages of Genferon contain 5 or 10 pieces of medicinal suppositories.

Compound

Each suppository has a mass of about 1.60 g. The composition contains 3 active elements:

1. by type alpha-2b - 250,000, 500,000 or 1,000,000 IU. It has a negative effect on viruses and microbes. The immunomodulatory effect is achieved by enhancing the response of the immune system. Leukocytes, which are contained on mucous tissues, under the influence of interferon, begin to more actively eliminate foci of infection.
2. Taurine - 0.01 g. It normalizes metabolic reactions, has a positive effect on tissue regeneration. Taurine has a pronounced antioxidant effect, it interacts with oxygen, due to the excessive accumulation of which pathological conditions develop. Taurine increases the medicinal qualities of interferon.
3. Anestezin - 0.055 g. This is an anesthetic with local action. It prevents pain impulses from arising by blocking them in the nerve endings. Anestezin has only a local effect, it is not absorbed into the blood plasma.

As additional substances, the manufacturer uses sodium citrate, dextran, polyethylene oxide, citric acid, tween, purified water and fat in solid form.

pharmachologic effect

With rectal administration of the agent, a significant degree of interferon exposure is noticeable, due to which it is possible to achieve a pronounced immunomodulatory result. In the case of intravaginal use, bacteria and viruses are quickly eliminated from the affected area, but the systemic effect is practically not expressed due to the poor ability of the vaginal mucosa to absorb substances for further distribution throughout the body.

In the blood, the highest concentration of interferon is observed 6 hours after the introduction of the candle. The active components of the drug are excreted from the body through the kidneys 12 hours after the use of the suppository, so it is recommended to use the drug 2 times a day to maintain its effect.

Indications for use

Genferon can act as an independent agent or as one of the drugs in complex therapy against inflammatory and infectious phenomena of the urinary system. Its use is indicated for men, women (including during pregnancy) and children. Therapy based on this drug is used to eliminate:

• ureaplasmosis, mycoplasmosis, chlamydia;
• gardnerellosis, trichomoniasis;
• vaginal candidiasis;
• bacterial vaginosis;
• cystitis that has become chronic;
• cervicitis (diseases of the cervical canal);
• bartholinitis (inflammatory process in the Bartholin glands);
• vulvovaginitis (inflammation in the vagina);
• adnexitis (inflammatory disease of the ovaries);
• erosive lesions of the cervix;
• urethritis (the process of inflammation in the urethra);
• balanitis (inflammation of the glans penis) and balanoposthitis (an inflammatory disease that affects the upper part along with the foreskin).

Contraindications

The drug can not be used in the case when the patient's body does not tolerate interferon or other substances from the composition of the drug.

1. During exacerbations of autoimmune diseases.
2. If you have allergies.
3. During the first three months of pregnancy.
4. With type 1 diabetes.
5. For children under six years of age.

During lactation, this medication can be used, it is important not to exceed the allowable dosage.

Rules for use and dosage

This medicine is used differently in men, women and children. Women are shown the following treatment regimens:

1. : assigned to 1 supp. 2 times a day for 10 days. The drug is injected into the vagina. With a protracted illness, they put 1 candle every other day, in this case, the course of treatment increases to 2-3 months.
2. In acute vaginal inflammation, it is necessary to apply one suppository vaginally after waking up (dosage 500,000 IU) and one suppository rectally at night (dosage 1,000,000 IU) along with the introduction of a fungicidal suppository into the vagina.
3. Pregnant women, in order to normalize local immunity in the treatment of urogenital infections, are prescribed twice a day for 1 candle (250,000 IU) of the drug. The duration of therapy is 9-12 days. Such treatment is suitable for 13-40 weeks of pregnancy, before the 13th week such therapy is contraindicated.

In men, the treatment of diseases of the genitourinary area that have arisen due to any infection is carried out with Genferon suppositories with the highest possible dosage. The drug is injected into the anus: it is necessary to use one suppository twice / day for ten days. To increase the effectiveness of the drug, it is possible to carry out vitamin therapy with vitamins C and B in parallel with the main treatment.

Treatment of children

For the treatment of young patients, Genferon-Light is suitable, which contains 125,000 IU of interferon. This tool is used for children from 7 to 15 years. After reaching the age of 15, adolescents can be treated with conventional Genferon. For children under 7 years of age, Genferon is used only after the appointment of a pediatrician.

This medication is usually prescribed for children with urinary tract infections or the appearance of viral diseases. Candles are injected only into the rectum. It is necessary to avoid intravaginal administration of suppositories to girls under seven years of age, since this can seriously disrupt the microflora of the child.

In the presence of an acute infection caused by a virus, 1 suppository is injected twice a day into the anus (course - 6 days, with a chronic stage of the disease - 10 days). After the end of treatment, to prevent the recurrence of infection, put 1 supp. in the anus at bedtime 1 time / 2 days (duration of preventive treatment - 1-2 months).

In diseases of the genital organs and the excretory system, children are prescribed a ten-day course of rectal administration of the drug (1 supp. 2 times / day). The interval between the use of the product should not be more than 12 hours. Treatment of children should be accompanied by vitamin therapy (C and A) and.

Overdose

The occurrence of an overdose of Genferon was not detected. If too many suppositories were administered at a time, it is necessary to stop the administration of suppositories for one day, and then continue with the usual treatment.

Adverse reactions

Usually the drug is easily tolerated by patients. Sometimes local allergies occur, which manifest themselves as a slight burning sensation of the vagina, this phenomenon disappears 48 hours after stopping treatment with Genferon. It is necessary to consult a doctor before continuing therapy.

When taking interferon, fatigue, slight fever, fever, pain in the head and muscles, thrombocytopenia or leukocytopenia may occur if the body has received more than 10,000,000 IU of interferon during the day. However, no cases with such severe adverse reactions have been reported to date. With an increase in body temperature, it is recommended to take 1-2 tablets of paracetamol once.

special instructions

Candles Genferon are especially effective when taking antibiotics and other drugs with antimicrobial action, which are suitable for the treatment of urological diseases. The action of anesthesin is enhanced by non-narcotic analgesics. Anestezin reduces the effect of sulfonamides against bacteria.

To avoid re-infection from a sexual partner, it is recommended that the couple be treated together. Genferon can be used during menstruation. This tool does not affect the speed of reaction, does not reduce attention, and therefore does not interfere with driving a car or performing dangerous work.

Opinions about the drug

The opinion of doctors and reviews of patients who were treated with candles Genefron:

I often prescribe Genferon suppositories to my patients. This is a good drug that rarely causes side effects, which is especially important for use during pregnancy. Of course, he cannot cure chlamydia or ureaplasmosis; in such cases, combination therapy of several drugs is needed. But Genferon shows itself well in the treatment of thrush, vulvovaginitis,.

Maria Sergeevna, obstetrician-gynecologist

Genferon helps to quickly cure infectious diseases in children. Although children do not like the release form in the form of candles, it is thanks to it that the drug is quickly absorbed and begins to heal the body.

Svetlana Vladislavovna, pediatrician

During the examination, the gynecologist discovered a slight erosion, suggested not to cauterize it, but to try putting Genferon candles for 3 weeks. I put them twice a day, as advised by the doctor. The only negative that I felt was that the candles dissolve too slowly. But after the end of the treatment, the erosion disappeared, and this is the main thing!

Veronica, 34 years old

I treated cystitis with Genferon, which appeared in me 5 times a year. The drug did not cause any side effects for me, there was not even a burning sensation from candles. I took Genferon for a long time, but it was worth it, because the cystitis went away.

Olga, 23 years old

Genferon was prescribed to me by a doctor for inflammation in the ovaries. It took about two weeks to put candles. A couple of days after taking it, a strong burning sensation in the vagina began, I had to cancel the drug and be treated in other ways. Genferon did not suit me, it only caused an allergy. But the child was prescribed this remedy by a pediatrician for inflammation in the urethra. Children's Genferon helped, although I was afraid of a side effect.

Natalia, 30 years old

Price

The cost of this remedy depends on the dosage of the active substance:

• pack of 10 pieces (125 thousand IU) - from 290 rubles;
• pack of 10 pieces (250 thousand IU) - from 350 rubles;
• pack of 10 pieces (500 thousand IU) - from 550 rubles;
• pack of 10 pieces (1 million IU) - from 770 rubles.

Rules for storage and dispensing in a pharmacy

The drug retains its beneficial effect at a temperature regime of 2 to 9 C. The place where the drug is stored should be inaccessible to children. The drug is not used after the expiration date, i.e. after two years. Genferon can be purchased at the pharmacy with a prescription.

Analogues

Genferon has such analogues among drugs with a similar effect:

1. - antiviral agent in the form of candles. It has a similar list of indications for use. It is allowed after 14 weeks of pregnancy, as well as during lactation.
2. Kipferon - suitable for the treatment of the same diseases as Genferon. Kipferon is active against rotavirus, staphylococcal infections, and also eliminates.
3. Transfer factor - capsules with an immunomodulatory agent. Has no contraindications. It has a beneficial effect on the DNA of the infected cell, due to which the disease quickly recedes.
4. Interferon and Giaferon - completely coincide in composition and action with Genferon. There is little difference in treatment regimens. Suitable for children.
5. - increases the production of immunoglobulins, thereby increasing the body's resistance to viruses and bacteria.

Genferon vaginal suppositories exhibit local and systemic immunostimulatory effects, the drug was developed by Russian scientists.

General characteristics of the drug

Genferon is not an antibiotic, but an immunomodulatory drug. Its structure includes three basic ingredients - interferon α-2b, taurine and benzocaine. The effect of this drug on the body is determined by the properties of its main content - interferon alfa-2b. It is this substance that destroys the structure of viruses and chlamydia.

In the process of using Genferon suppositories, activation of immunocompetent cells is observed. Due to this, the natural protection of the body from the effects of pathogenic agents is provided. Interferon stimulates the formation of class A Ig, which is synthesized in the epithelial cells of the intestinal mucosa.

Taurine is a sulfonic acid formed in the body from the amino acid cysteine. This compound normalizes metabolic processes in the affected organs, enhances the process of tissue regeneration, exhibits hepatoprotective, anti-inflammatory, reparative, antioxidant and membrane-stabilizing effects.

Taurine also prevents the formation and accumulation of products of lipid peroxidation and oxidative modification of proteins in cells. The above compound enhances the biological activity of interferon. Benzocaine has a local anesthetic effect, blocks the appearance of pain.

Candles Genferon improve the general condition of the patient, eliminate such unpleasant symptoms as pain, itching and burning.

Anestezin reduces the permeability of biomembranes for Na + ions, displaces calcium ions from receptors located on the inner surface of the membrane, and blocks the transmission of nerve impulses. In the process of using the drug, the analgesic effect can be traced in just a few minutes. Anestezin penetrates into the lymphatic system, as a result of which the systemic effect of the drug is ensured.

In addition to the basic elements, Genferon also includes additional substances:

• deionized water;
• dextran 60000;
• sodium citrate;
• twin 80;
• polyethylene glycol 1500;
• citrate acid;
• emulsifier T 2 ;
• animal triglycerides.

Note: Genferon exhibits a pronounced therapeutic effect, which allows to effectively eliminate chronic inflammatory reactions in the organs of the genitourinary apparatus. In addition, according to many scientists, the drug is the safest among analogues.

Indications for use

Many are looking for information on how and in what cases can Genferon be used? The instructions for use indicate that this agent can be used as an effective immunostimulant. There are also references to the fact that this medication can be used as an independent antiviral agent.

Genferon is prescribed for both intravaginal and rectal use. The method of administration of the drug and its dosage is determined by gender, age and severity of the clinical course of the disease.

With rectal or vaginal use, the active ingredients of the drug penetrate the blood and lymph very quickly. Some of the drug remains on the mucous membrane and has a local effect. In the presence of extensive inflammatory processes in patients, the vaginal setting of suppositories is combined with rectal.

The highest level of interferon in the blood plasma is observed five hours after the use of the suppository. Since the half-life of the drug is about twelve hours, it is best to use it twice a day.

The course of therapy should be at least ten days. In the presence of chronic pathologies, the drug can be used for up to three months. In this case, it is better to use the medicine every other day.

Genferon is effectively used in the presence of the following pathologies:

• andexite;
• bartholinitis;
• colpitis;
• chlamydia;
• trichomoniasis;
• ureplasmosis;
• mycoplasmosis;
• balanitis;
• bacterial vaginosis;
• anogenital herpesvirus infection;
• vulvovaginitis;
• cystitis;
• urogenital candidiasis;
• prostatitis;
• urethritis;
• gardnerellosis;
• papillomavirus infection;
• erosion and ectropion of the cervix.

The main advantages of the immunomodulator include the following indicators:

• high bioavailability (efficacy) of the drug;
• pronounced antiviral, immunomodulatory, antimicrobial, antiproliferative, antioxidant, reparative action;
• optimal price / quality ratio;
• the possibility of using during menstruation;
• ease of use;
• the possibility of complex use with other medicines.

Despite the excellent characteristics, suppositories in gynecologists cannot be used on their own. It is very important to consult a specialist before using medications. This is especially true for patients who have problems with dysfunction of the cardiovascular and endocrine systems (hypertension, diabetes, obesity, Basedow's disease, hypothyroidism, etc.).

Features of use during pregnancy and ureaplasmosis

Many expectant mothers ask: "Is it possible to use Genferon during pregnancy?". As a result of many years of research, researchers have proven the safety of intravaginal use of the drug from 13 to 40 weeks of pregnancy.

Candles are actively used for the treatment of infectious pathologies of the genitourinary apparatus in the second trimester of pregnancy. The bioactive ingredients that make up the drug activate a number of enzymatic reactions in the mother's body, which prevent the virus from spreading. This increases the body's immune resistance.

Genferon is prescribed for the treatment of trichomoniasis, thrush, anogenital herpesvirus infection, relief of pain and itching in the genital area. With ureaplasmosis, immunostimulants are best combined with antimicrobial drugs.

The treatment regimen for ureplasma is chosen by the attending physician. On average, the duration of the course of therapy is from two to three weeks. To effectively eliminate the disease, the doctor prescribes antibiotics and Genferon suppository.

Treatment of ureaplasma in women with the help of this medication occurs according to the scheme: a course of taking 10 days, 2 suppositories per day. The chronic form of ureaplasmosis requires longer therapy.

Often, Genferon is prescribed after childbirth. However, breastfeeding is not a contraindication. The suppository has proven itself in the treatment of various anomalies associated with dysfunction of the genitourinary apparatus.

Interaction with other medicines and analogues of the drug

The complex use of Genferon with antibacterial agents enhances the effectiveness of the treatment of infectious pathologies. The following medicines enhance the analgesic effect of benzocaine.

Non-steroidal anti-inflammatory drugs:

Sulfonamides together with Genferon should not be prescribed, as they lose some of their activity against pathogenic bacteria. Not a bad result is obtained when the immunomodulator is used together with fat- and water-soluble vitamins (tocopherol and ascorbic acid).

Genferon does not affect the ability to drive a car at all, does not interfere with the performance of hazardous activities that require increased attention and concentration. Analogues are represented by such drugs as Giaferon, Kipferon, Vitaferon.

Side effects of the drug and contraindications

In the process of using Genferon, a number of undesirable phenomena may appear:

• allergic skin rashes;
• sleep disturbance;
• hyperthermia;
• chills;
• colic;
• anorexia;
• arthralgia;
• myalgia;
• itching and burning in the perineum;
• migraine;
• dizziness;
• hyperhidrosis;
• increased fatigue;
• loss of appetite;
• thrombocytopenia and leukocytopenia.

If such phenomena are detected, it is necessary to stop taking the medication and seek the advice of a specialist.

The presence of hypersensitivity or allergy to any ingredient of the drug is an absolute contraindication to its use. The medication should also be limited in the following cases:

• the presence of autoimmune pathologies (diffuse toxic goiter, glomerulonephritis, diabetes mellitus, rheumatoid arthritis, Hashimoto's thyroiditis, erythematous chroniosepsis, multiple sclerosis, etc.);
• exacerbation of allergic reactions;
• I trimester of pregnancy;
• epilepsy;
• severe diseases of the heart, liver and kidneys;
• children under the age of seven.

A qualified specialist should decide on the appointment of Genferon or its analogues, it is not worth self-medicating.

Reviews

Reviews of doctors and patients indicate that the above medicine is well tolerated and practically does not cause various complications. Practitioners claim that Genferon, unlike its analogues, exhibits a pronounced analgesic and regenerative effect. This is especially true in the treatment of diseases of the cervix. The anesthetic included in the structure of the drug perfectly copes with its function.

Doctors assure that Genferon is absolutely safe, because it is not an antibiotic. That is why it can be prescribed even to patients during the period of bearing a child and breastfeeding him.

This medication almost never shows side effects, but if the dosage is not observed, some discomfort in the anogenital region may be observed. That is why before taking the medication, you should consult a doctor, or at least carefully study the instructions for using the drug. Patient reviews confirm the information that Genferon is a fairly effective antiviral agent, which, with complex treatment, shows an excellent result.

Also, patients note that the drug does not contain oils and paraffin, so it never stains underwear. Due to this, the pharmaceutical agent does not cause any discomfort to women. In most cases, reviews of the above described drug are positive. However, negative reviews can also be found on the Internet, which is obviously related to the misuse of the medication or the presence of an allergy to its components.

Summing up, it should be noted that Genferon suppositories are an effective, safe pharmaceutical substance with antiviral and immunomodulatory effects, used to treat various pathologies of the genitourinary system of men and women.

Genferon candles - instructions for use, dosages, analogues and prices

Latin name: Genferon

Active ingredient: Interferon

alpha 2b + Taurine + Benzocaine

Manufacturer: Biocard, Russia

Pharmacy dispensing condition: By prescription

"Genferon" is an immunomodulator and at the same time an antiviral agent. Its use allows you to effectively deal with various inflammatory processes and a number of pathogens of infectious diseases. First of all, this drug is used for diseases of the genitourinary system in women and men (thrush, genital herpes, papillomas, cystitis, prostatitis and others).

If the drug is administered rectally, a systemic effect is achieved from its use, which makes it possible to treat viral and bacterial diseases of the respiratory system with its help, as well as to prevent diseases by increasing immunity. For those to whom the doctor prescribed "Genferon", instructions for its use are simply necessary.

Indications for use

The reception of "Genferon" is indicated for various infectious diseases, the causative agents of which are viruses, bacteria, protozoa, fungi. It is used to treat:

• Diseases of the male and female genital area caused by the herpes virus, HPV (human papillomavirus), gardnerella, mycoplasma, ureplasma, chlamydia, trichomonas, candida and other microorganisms
• Colds - acute respiratory infections and acute respiratory viral infections, acute bronchitis, etc.
• Diseases of the urinary tract, in particular, bacterial chronic cystitis.

Compound

It includes three active ingredients that complement each other in medicinal properties:

• Human interferon alpha-2b, recombinant (rhIFN-α-2b). Obtained by synthesis by Escherichia coli, which transplanted the corresponding gene. Has a pronounced immunomodulatory, antiviral and antibacterial effect
• Taurine. Antioxidant and membrane stabilizer. Increases the effective work of interferon, as well as the restoration of damaged tissues
• Benzocaine (sometimes an anesthetic is used instead). A local anesthetic.

In addition to the main active ingredients, candles include additional substances: solid fat and others (T2 emulsifier, sodium citrate, purified water, and others).

Medicinal properties

"Genferon" candles can be used:

• Rectally. In this case, a complex effect on the body is provided, since the drug is well absorbed into the blood and lymph flow through the mucous membrane of the rectum.
• Vaginally. The permeability of the vaginal epithelium is much lower than that of the intestine. Therefore, in this case, the local action of “Genferon” is achieved.

Pharmacological features of the drug are determined by the combined effect of the impact of its constituent parts:

• Interferon alpha-2b has an antiviral effect by suppressing the replication of viruses (HPV, herpes, and others). The immunomodulatory effect is achieved by increasing the concentration of phagocytes, monocytes, macrophages and other cells related to natural killers. This contributes to the immune response to infection, the destruction of its foci and the resumption of the production of antibodies of the Ig A type there. Mediated immunoreactions determine the antimicrobial effect of "Genferon"
• Taurine catalyzes the action of interferon; plays an antioxidant role, removing reactive oxygen species and thereby reducing inflammation; promotes cellular regeneration
• Benzocaine blocks pain impulses in nerve cells, which causes a local anesthetic effect. It is not absorbed into the blood, affecting the injection site.

The concentration of the main active substance - interferon - decreases after 12 hours. Therefore, to achieve the maximum therapeutic effect, the drug should be used twice a day. Its components are excreted from the body by the kidneys.

The average price is from 350 to 750 rubles.

Release forms

"Genferon" candles are cone-shaped suppositories with a pointed tip. The color is white, there may be a light yellow tint. Due to the excipients, they do not melt in the hands, which is convenient when administered.

There are four types of suppositories that differ in the concentration of interferon: “Genferon” IU, “Genferon” IU, “Genferon” IU and “Genferon light” (which you can read about here).

The carton can contain 5 or 10 suppositories packed in a plastic shell.

Mode of application

Candles are administered vaginally or rectally, depending on the gender of the patient, the nature of the disease and the prescribed therapy.

For the treatment of diseases of the genitourinary system, women are prescribed 2 times in 12 hours, one suppository with a dosage of 500 thousand IU or 1000 thousand IU. As a rule, this is a vaginal administration. The duration of treatment is up to 10 days. In the treatment of the chronic form of the disease, 1 suppository is used three times a week, with an interval of one day, for 1-3 months.

You can use candles during menstruation.

In acute infectious inflammation of the female genital tract, complex therapy is used:

1. In the morning vaginally Genferon 500 thousand IU
2. In the evening Genferon 1000 thousand IU rectally and additionally vaginal suppositories with an antibacterial effect (for example, Hexicon).

Men, in particular "Genferon" for prostatitis, are shown to use suppositories rectally twice a day, with a dosage of either IU, depending on the severity of the disease. Use the drug for no longer than 10 days.

Under the supervision of a doctor, you can use "Genferon" for children, with different dosages, depending on the age of the patient:

• 1-7 years old - the pediatrician may prescribe "Genferon Light" (IU)
• 7-14 years - the dosage is increased to 250 thousand IU
• Over 14 years old - dosages similar to adults: 250 thousand IU, 500 thousand IU, or same IU, depending on the severity of the disease.

Candles, which are slightly smaller than usual, are injected into the rectum after 12 hours. Duration of admission - 5 days. If the child has a relapse of a chronic disease or the disease has taken a protracted form, the doctor may add another 5-day course of treatment.

It is possible to use the drug for prophylactic purposes: one suppository at night, every other day. Preventive use of the drug is from 1 to 3 months.

During pregnancy and breastfeeding

When deciding whether to use "Genferon" for the treatment of pregnant women, the doctor must balance the benefits for the mother to the harm that can be done to the child. The drug is prescribed no earlier than the 12th week of pregnancy. This drug is used in systemic therapy for detected ureaplasma, thrush, herpes virus, HPV, cystitis and other viral and bacterial diseases.

"Genferon" is not prescribed during lactation.

Contraindications

It is forbidden to use candles under the following conditions: the first trimester of pregnancy and an individual allergic reaction to the substances that make up it.

Precautionary measures

Restriction to the use of the drug are exacerbations of autoimmune diseases and allergies of various etiologies.

"Genferon" and alcohol are combined in very small doses of the latter. It is not recommended to exceed it, since alcohol worsens the effect of interferon, but at the same time increases side effects. Therefore, "Genferon" and alcohol is a completely dubious combination, as in most cases with drugs.

Cross-drug interactions

The use of "Genferon" with vitamins E and C, which accelerate the action of interferon, is shown.

In complex therapy, the drug is prescribed with other antimicrobial drugs or antibiotics. For example, it goes well with Terzhinan vaginal suppositories. They include:

• The antifungal agent nystatin
• Aminoglycoside antibiotic neomycin sulfate
• A substance of the imidazole group ternidazole, which works against anaerobic microorganisms, including Trichomonas and Gardnerella
• The corticosteroid prednisolone sodium metasulfobenzoate is a local anti-inflammatory agent.

"Terzhinan" with "Genferon" effectively interact with cystitis, thrush and other infectious diseases of the genitourinary system.

Another antiseptic that interacts well with Genferon is Hexicon. Its main active ingredient is chlorhexidine. "Hexicon" is produced in the form of vaginal suppositories and a solution. Effective against a number of infectious agents of various etiologies and locations.

Side effects

Basically, there are local symptoms of allergies: itching and burning in the vagina. They go away by themselves a couple of days after the end of the drug. The possibility of its further use should be discussed with your doctor.

When using candles with a total dose of IU per day, reactions are possible that are characteristic of all types of interferon:

• On the part of the hematopoietic system - a decrease in the content of platelets and leukocytes in the blood (thrombocyto- and leukopenia)
• From the side of the central nervous system - headaches, loss of appetite, fatigue
• From the musculoskeletal system - pain in the muscles and joints (myalgia and arthralgia)
• Others - hyperthermia (increased body temperature), hyperhidrosis (excessive sweating).

When the temperature rises, paracetamol or ibuprofen (Nurofen) can be used.

Overdose

Until this time, cases of excessive use of the drug have not been recorded.

Terms and conditions of storage

The drug can be stored in the refrigerator, at a temperature not lower than +2 and not higher than +8 degrees, away from children, no longer than two years from the date of manufacture.

Analogues

"Panavir"

Green oak forest, Russia

The main active ingredient is an extract from a plant of the nightshade family Solanum tuberosum. "Panavir" promotes the production of immunoglobulin A and leukocytes. It also increases the body's resistance to various pathogens of infectious diseases. The high efficiency of the drug "Panavir" for the fight against HPV is noted. After applying its various dosage forms, papillomas disappear.

• Several dosage forms: injection solution, topical gel, rectal suppositories, inlight spray gel
• Has a bright antipyretic effect - no need to use additional funds
• Favorably affects the retina of the eyes, the regeneration of the gastric mucosa.

• Not to be used by children under 12 years of age
• High price for injections.

"Viferon"

Almost identical to "Genferon", since the main active ingredient is interferon. "Viferon" is available in the form of a gel, ointment and rectal suppositories with a dosage of: ED, ED, ED, and ED. The first dosage forms are used in gynecology for the treatment of genital tract infections in women.

• There are auxiliary substances - vitamins C and E, which enhance the effect of interferon
• Can be used from birth

Genferon candles - instructions for use, analogues, price and reviews

Description

Release form

1. Genferon - contains interferon alpha 2b in the amount of IU.

2. Genferon - contains interferon alpha 2b in the amount of IU.

3. Genferon - contains interferon alpha 2b in the amount of IU.

Compound

1. Human interferon alpha 2b at a dosage of IU, IU and IU.

2. Aminosulfonic acid - taurine in the amount of 0.01 g.

3. Local anesthetic - benzocaine or anesthesin in the amount of 0.055 g.

Absorption, distribution and excretion from the body

The introduction of Genferon into the rectum leads to close contact of the drug with the mucosa, rich in blood and lymphatic vessels, due to which the active components are freely absorbed into the blood. When injected into the rectum, approximately 80% of the dose is absorbed into the bloodstream. The maximum concentration of active components in the blood is observed 5 hours after the administration of suppositories. The high degree of absorption of the drug into the blood allows the drug to have not only a local, but also a systemic effect.

With the introduction of Genferon into the vagina, a grown local effect is achieved with the accumulation of a large part of the dose in the pathological focus. The mucous membrane of the vagina does not have a high absorption capacity, so the entry of active components into the bloodstream is minimal. Due to this circumstance, when administered vaginally, the drug has mainly a local effect, and only a slight systemic effect. The maximum concentration in the bloodstream and in the focus of inflammation on the mucous membrane is reached, on average, 5 hours after the administration of suppositories.

Therapeutic effects (principles of treatment)

Effects of interferon

• antiviral action;
• antibacterial action;
• immunomodulatory action;
• antiproliferative action (stopping the reproduction of pathogenic microorganisms).

Genferon has an antiviral effect by acting on specific enzymes that help stop the reproduction of viruses. In addition to the activation of enzymes, Genferon directly suppresses signals for the reproduction of a viral particle.

Effects of taurine

• strengthening of metabolic processes;
• acceleration of tissue repair processes (regeneration);
• normalizes the properties of cell membranes, increasing the stability and viability of cells;
• anti-inflammatory property;
• immunomodulatory effect;
• antioxidant action associated with the neutralization of free radicals and stopping chain reactions of peroxidation;
• enhances the activity of interferon alpha 2b.

Effects of benzocaine

1. Blocks the conduction of pain along the nerve fibers.

2. They block the perception of pain by the processes of nerve cells.

Indications

Genferon is indicated for the following diseases:

• genital herpes;
• chlamydia;
• ureaplasmosis;
• mycoplasmosis;
• candidiasis of the vulva and vagina (for example, chronic recurrent vulvovaginal candidiasis);
• gardnerellosis;
• trichomoniasis;
• human papilloma virus (papilloma and condylomas);
• bacterial vaginosis;
• cervical erosion;
• cervicitis (inflammation of the cervical canal);
• vulvovaginitis (inflammation of the vagina and vestibule);
• bartholinitis (inflammation of the Bartholin glands);
• adnexitis (inflammation of the ovaries);
• inflammation of the prostate gland (prostatitis) in men;
• urethritis (inflammation of the urethra);
• balanitis (inflammation of the glans penis);
• balanoposthitis (combined inflammation of the glans penis and foreskin);
• viral hepatitis.

Contraindications

• autoimmune diseases (eg, Hashimoto's thyroiditis, systemic lupus erythematosus, type I diabetes mellitus, glomerulonephritis, etc.);
• exacerbation of allergic conditions;
• pregnancy up to 12 weeks;
• children's age up to 7 years.

Instructions for use

Scheme of application for women

Scheme of application for men

Scheme of application for children

Overdose

Side effects

Rarely, while taking the drug Genferon, the following side effects develop:

The above side effects most often develop with a daily dose of Genferon more than 0 IU.

Interaction with other drugs

1. Non-steroidal anti-inflammatory drugs:

Sulfanilamide preparations, when used in conjunction with Genferon, lose some of their effectiveness against pathogenic microorganisms.

special instructions

Genferon during pregnancy

The use of Genefron in children

Reviews

The use of Genefron in children - reviews

Genferon or Viferon - which is better?

Analogues

• lyophilisate for the preparation of Avonex solution;
• solution for intramuscular injection Avonex;
• solution for injections Altevir;
• Alfaron lyophilisate (for intranasal administration and for injections);
• solution for injection Alfaferon;
• lyophilizate Betaferon (for subcutaneous administration);
• gel for local use Viferon;
• ointment for local use Viferon;
• rectal suppositories Viferon;
• Genfaxon solution (for subcutaneous injection);
• suppositories vaginal and rectal Giaferon;
• ointment for topical application Diaferon;
• lyophilizate Ingaron (for intramuscular, subcutaneous and intranasal use);
• lyophilisate Interal-P (for injections);
• lyophilizate Interferal (for injections);
• interferon recombinant human dry Rekolin (for injections);
• injection solution - human leukocyte interferon;
• solution for topical application - human leukocyte interferon;
• rectal suppositories - human leukocyte interferon;
• recombinant ointment - Interferon alfa-2 (for local and external use);
• Intron A solution (for intravenous and subcutaneous use);
• gel Infagel (for local use);
• lyophilisate Inferon (for intramuscular injections);
• Infibeta lyophilisate (for injection);
• lyophilisate Laifferon (for intramuscular and ocular use);
• Laifferon solution (for intramuscular and ocular use);
• Lyophilizate Leukinferon (for injection);
• lyophilizate Lokferon (for topical application);
• Pegasys solution in vials and syringe tubes (for subcutaneous injection);
• lyophilisate Intron (for subcutaneous administration);
• Realdiron lyophilisate (for intramuscular and subcutaneous use);
• lyophilizate Reaferon (for injections and topical application);
• lyophilisate Reaferon-EC (for injections and topical application);
• Rebif solution (for subcutaneous use);
• Ronbetal solution (for subcutaneous use);
• Roferon-A solution (for subcutaneous use);
• rectal suppositories Sveferon;
• lyophilizate Sinnoveks (for intramuscular injections);
• Eberon Alpha R lyophilisate (for injections);
• Extavia lyophilisate (for subcutaneous injection).

Instructions for use of vaginal and rectal suppositories Genferon - composition, side effects and analogues

The drug belongs to the category of immunomodulators and at the same time has an antibacterial effect. The use of the drug is justified in the presence of various inflammatory pathologies caused by a number of pathogenic bacteria. Often, Genferon suppositories are used to treat the organs of the genitourinary tract (for thrush, cystitis, prostatitis, genital herpes), while not only the symptoms of the disease are eliminated, but also the cause of inflammation.

Genferon candles - instructions for use

The drug is an immunomodulatory complex of substances that has an antimicrobial, anti-inflammatory effect. As a rule, Genferon is used to treat diseases of the genitourinary system in men and women. The antiviral effect of the drug extends to a significant group of pathogenic microorganisms - bacteria, viruses, fungi, etc. The immunomodulatory effect of suppositories is manifested due to the activation of immune defense links that ensure the destruction of long-lived bacteria that provoke chronic inflammation.

The components of the drug provide systemic and local action, activating certain elements of the immune system that act in the blood and on the mucous membranes. With rectal administration, a systemic effect is achieved, which makes it possible to treat bacterial, viral diseases of the respiratory system with Genferon or to prevent many other pathologies by activating immune cells and generally strengthening the protective properties of the body.

Compound

The main component of the drug is human interferon alpha 2B, in the preparation it can be in a dosage of 250, 500 thousand or IU. Other active substances in the composition of the drug are:

• aminosulfonic acid (0.01 g);
• benzocaine or anestezin (0.055 g).

Since the active ingredients need a special environment for the fastest penetration into the circulatory system and fixation on the mucous membrane of the vagina or rectum, the basis of the drug is solid fat. All active substances and other auxiliary components are evenly distributed in it, which include:

• emulsifier T2;
• dextran 60 thousand;
• sodium hydrocitrate;
• macrogol 1500;
• lemon acid;
• purified water;
• polysorbate 80.

Release form

The medication is presented as suppositories for rectal or vaginal use. The shape of the suppositories resembles a white cylinder with a sharp end. The internal structure of the candles is homogeneous, an air rod or a small depression in the form of a funnel is visible in the section. The drug is available in packs of 10 or 5 suppositories, depending on the dose of interferon, it is divided into 3 types:

Pharmacodynamics and pharmacokinetics

The introduction of suppositories into the rectum ensures close contact of the mucosa with the drug, due to which the active components of rectal suppositories are absorbed into the bloodstream by 80%. The maximum concentration of interferon and other active substances in the blood is observed 5 hours after the use of Genferon. Good absorption of the drug provides both local and systemic therapeutic effects.

With the vaginal use of suppositories, the maximum local therapeutic effect is achieved, which is due to the accumulation of most of the drug in the foci of infection. The mucous membrane of the vagina cannot provide high absorption, therefore, in this case, the penetration of the active substances of Genferon into the blood is minimal. The drug undergoes breakdown into metabolites, after which it is removed in the urine within 12 hours.

Candles Genferon - indications for use

The systemic immunomodulatory drug has a wide spectrum of action: it has found application in the complex therapy of various infections of the genitourinary system in women and men. In addition, Genferon is used as an independent drug, and as part of complex treatment with other medicines and methods. Candles with interferon are indicated for the treatment of HPV and for such diseases:

• vaginal candidiasis;
• herpes viruses;
• chlamydia;
• mycoplasmosis;
• candidiasis of the vulva;
• ureaplasmosis;
• adnexitis;
• viral hepatitis;
• trichomoniasis;
• erosion of the cervix;
• bartholinite;
• vaginosis;
• cervicitis;
• gardnerellosis;
• urethritis;
• inflammation of the prostate gland;
• other sexual infections and urogenital diseases.

Contraindications

It is forbidden to use suppositories in case of an allergic reaction or sensitivity to certain components of the medication. In addition, conditional contraindications to the drug, which you should definitely tell your doctor about, are:

• autoimmune pathologies;
• early pregnancy (first trimester);
• children's age (up to 7 years);
• allergy in the acute stage.

Method of application and dosage

Candles with recombinant interferon are administered vaginally or rectally, depending on the specifics of the disease and the gender of the patient. Genferon completely dissolves, in contact with the mucous membrane of the rectum or vagina, without causing discomfort. With vaginal administration, a more pronounced local effect is achieved, with rectal administration, a systemic effect is provided. The latter type of drug can even be prescribed for the treatment of acute respiratory viral infections or other infectious pathologies of different localization.

Vaginal suppositories Genferon

In gynecology and in inflammatory pathologies, until the age of 7 years, the drug is prescribed in a dosage of IU. For adults and children over the age of seven, vaginal suppositories are prescribed in an individual dosage, depending on the severity of the disease, its clinical manifestations. For bacterial infections in the urogenital tract, doctors recommend suppositories with a dosage of thousands of IU once a day. The duration of therapy, as a rule, does not exceed 10 days.

If Genferon is used as a local anesthetic and anti-inflammatory agent for the treatment of cervical erosion or another disease, then in gynecology it is prescribed in the following scheme: 1 suppository of 500 thousand IU at night vaginally and rectally. In a chronic disease, a three-month therapy is prescribed, which involves the introduction of suppositories into the vagina 3 times a week.

Rectal administration

Candles with this use case allow the active substance to enter immediately into the intestines, and then into the blood. Genferon is administered rectally for the most effective treatment of inflammation of various localizations and for the treatment of male genital infections. In the case of protracted infectious processes in women, the drug is administered rectally, 1 suppository every second day for 1-3 months. For the treatment of men, suppositories are prescribed rectally at a dosage of 500 thousand or 1 million IU, while the use pattern remains the same.

Pediatricians prescribe Genferon Light to children, the instruction of which implies the following treatment regimen:

• with viral infections - 2 suppositories rectally with an interval of 12 hours (therapy lasts 5 days, then a break for 5 days follows and the treatment is repeated);
• in case of viral chronic infections, Genferon is administered rectally to the child at night every other day (the course is 1-3 months).

Candles Genferon - instructions, application, prices, analogues and reviews

Genferon - candles for the treatment of genital infections. One suppository may contain 125, 250, 500 or 1000 thousand interferons (in the instructions there is information on choosing a dosage). In addition to urogenital diseases, genferon is effective against common infections - viruses, bacteria, fungi. What provides the therapeutic properties of the drug? And how to use it to treat genital infection?

Genferon - composition and action

Genferon is produced in the form of suppositories (suppositories) for insertion into the vagina or anus. The therapeutic effect of geneferon is provided by three active components:

• interferon (its amount can vary - 125, 250, 500 or thousand IU in 1 suppository);
• taurine (0.01 g in 1 suppository);
• benzocaine (0.055 g);

The shape of the suppository and the solid consistency of the preparation are provided by auxiliary components - fat, emulsifier, sodium citrate, citric acid, polyethylene oxide. What action does each component of geneferon provide?

Interferon

Interferon is a substance that is produced by the immune system. In the human body, interferon is formed when foreign cells invade ( predominantly viruses). Human interferons are conditionally divided into three groups (alpha, beta and gamma - α, β and γ). When different viruses invade, different types of interferons are formed.

Genferon suppositories contain recombined interferon alfa-2b. It is effective against a number of viral infections, many pathogenic bacteria, and some types of cancer. The word recombination means that the medicinal substance is not a blood product. It was obtained without the use of a donor's blood. How is interferon synthesized?

Interferon recombination is produced by Escherichia coli bacteria. The human interferon gene is inserted into their DNA. As a result, bacteria begin to produce (synthesize) human interferon, which fights infection (suppresses the synthesis of new viruses, stops their reproduction and further spread). It also stimulates the formation of other cells of the immune system ( macrophages).

Thus, the drugs have a double effect. Firstly, they introduce additional interferons into the blood (the help of someone else's immunity to fight infection). Secondly, they stimulate the formation of their own immune cells.

Taurine

Taurine - has a versatile effect on the human body ( prevents convulsions, improves heart function and breakdown of fats, restores the retina). It also protects cells, is responsible for their tone, restores the structure. In the human body, taurine is found in many vital organs.

Note: Pharmaceutical industry uses this substance extensively. It is part of various drugs - for the treatment of the liver, heart, diabetes, various infections.

As part of suppositories, taurine is a wound healing and anti-inflammatory component. It promotes tissue epithelialization, accelerates the healing of wounds and skin rashes. Reduces the area of ​​inflammation.

In addition, taurine retains the biological activity of interferon, and thus enhances the therapeutic effect.

Benzocaine

Benzocaine is an anesthetic component of Genferon suppositories (anesthetic). It blocks the passage of the nerve impulse and prevents the appearance of pain. An anesthetic is especially needed for painful infections and their relapses (for example, with herpes zoster, when the blistering rash not only itches, but also causes severe pain).

Genferon - stimulates own immunity. It enhances a weak immune response, helps to cope with a disease or infection at the moment, but does not always prevent infection and disease in the future. Therefore, the use of geneferon should not be uncontrolled, it is impossible to turn to treatment with immunostimulants for any reason. The drug is used for complex protracted infections or a low level of immunity.

Genferon: side effects and contraindications

For the drug geneferon, the instruction does not regulate any contraindications. However, for interferon (the main active ingredient in suppositories), the list of contraindications is quite wide. It is not recommended to be treated with drugs with interferon for the following diseases:

• Disorders of the heart, liver, kidneys.
• Disturbances in the central nervous system (namely, epilepsy).
• Diseases of the thyroid gland (with a diseased thyroid gland, interferon can cause hyperthyroidism).

What are the side effects of interferon treatment?

• s Cardiac arrhythmias. With great care, drugs are used in the treatment if there was a heart attack before.
• Drowsiness, headache. The drugs should not be combined with sedatives or sleeping pills.
• Loss of appetite, nausea and diarrhea - usually in those who have liver or biliary tract disease.
• s Allergic rashes.

More often than others, side effects occur together with large doses of the drug (500 itys. IU).

In addition, the drug is stranger» immunity. The recombinant component is safe in that it is not produced from blood and cannot become a source of infection. Its danger lies elsewhere - uncontrolled treatment with geneferon reduces one's own immunity, makes a person dependent on interferon intake from outside.

Candles genferon for children

Is Genferon used for children? Despite the novelty of the drug and medical disputes, geneferon is used to treat children from the first days of life. But only when necessary. For example, a child is not able to recover, their own immunity is greatly reduced, the body cannot cope with an infection, or complex surgical treatment is necessary.

Do not use genferon suppositories to treat the common cold, cough or cold. Even for the treatment of influenza in children, geneferon suppositories are used only for a protracted course of the disease, when the immune system is severely weakened and the body is unable to cope with the virus.

Advice: in the treatment of children, the smallest concentration of the active substance is used - Genferon Light 125. Due to the minimum amount of interferon, the likelihood of an allergic reaction from the use of these suppositories is the least.

Release forms

The mass of one candle is 1.65g. One package may contain 5 or 10 pieces. The amount of active substance (interferon) is measured in international units - IU.

Genferon contains ME. This minimum dosage is used to treat infants and preschoolers up to 7 years of age. Candles 125 are called Genferon Light. The use of Genferon Light is recommended not only for the treatment of children, but also for pregnant women (if there is a need to treat a sexual infection).

Genferon contains IU(in each suppository). This dosage is used to treat female genital infections in the initial and middle stages of development.

Genferon contains IU. This dosage is used to treat genital infections in men. It is also used to treat advanced genitourinary diseases in women.

Genferon - contains the maximum dose - IU. Used to treat complex infections, extensive inflammation, mainly in men.

The price of candles depends on the concentration of the active substance. The most expensive - candles IU.

What is treated with geneferon

Instructions for Genferon suppositories provide a list of infections in which the drug has a therapeutic effect:

• Herpes virus - more often used to treat the genital virus, but can also be used for oral and herpes zoster.
• HPV or human papillomavirus.

Bacterial infections:

• Chlamydia.
• Ureplasma.
• Mycoplasma.
• Gardnerellosis.
• Trichomoniasis.

As well as fungi (candidiasis). And yet - vulvovaginitis and cervicitis in women, prostatitis and urethritis in men.

Candles genferon - vaginal and rectal

Preparations with interferon have a form that ensures that the active substance enters the mucous membranes of the external organs. Interferon is destroyed in the stomach. Therefore, Genferon is produced in the form of candles or spray.

Rectal suppositories allow the active ingredient to enter immediately into the intestines, from where it is quickly absorbed into the blood. Therefore, rectal application is most effective for the treatment of general inflammation, as well as for the treatment of genital infections in men.

Sexual infections of women are treated with vaginal administration of the drug. In this case, geneferon has a local effect - it is almost not absorbed into the blood and is concentrated inside the vaginal cavity (the walls of the genital organs are characterized by low absorption capacity). Almost the entire drug remains inside and has a powerful therapeutic effect - it treats inflammation and destroys the pathogen.

Due to the weak absorption of the drug through the vagina into the blood, only genital infections in women are treated with vaginal administration of suppositories. All other cases of infection are subject to treatment by rectal administration of geneferon.

Often, for the treatment of complex protracted or extensive inflammation in women, vaginal suppositories are combined with rectal.

The use of candles for the treatment of women, men, children

• For the treatment of acute genital infections in women, they put 1 suppository (250 or 500 thousand IU) vaginally, morning and evening. The choice of dosage depends on the extent of inflammation and the causative agent of infection. Course of treatment - 10 days.
• For the treatment of chronic protracted infectious processes in women, 1 suppository is administered every other day within 1, 2 or 3 months.
• For the treatment of men, a dosage of 500 itys is chosen. ME. The treatment plan is the same 2 suppositories per day, 10 days or 1 suppository every other day for a month).

Genferon light is used to treat children. The instruction recommends the following scheme:

• For viral infections - 2 suppositories to the child rectally, with an interval of 12 hours. The course of treatment in children is less than in adults - 5 days. If necessary, extend the course, take a break for 5 days and repeat the treatment.

• In chronic viral infections in children, suppositories are administered rectally at night (every other day). A course of treatment - 1 to 3 months.

Genferon: analogues

The pharmacy industry offers many drugs in which interferon is the main active ingredient. They differ in name, additional components and the form of the drug (drops, spray, suppositories).

Viferon

These are rectal suppositories with interferon without additional substances. Each candle contains from ME. It is used to treat acute respiratory viral infections and pneumonia, intrauterine infection of newborns, hepatitis, genital infections, herpes. Viferon is administered only rectally. The drug is most effective against respiratory tract viruses.

Kipferon

These are suppositories for rectal and vaginal administration. They include interferon alpha 2 (in the amount of IU) from donor blood, as well as plasma proteins (to stabilize interferon) and immunoglobulins M, A, G. The presence of immunoglobulins, on the one hand, enhances the stimulating effect, increases the effectiveness of the drug in the fight against viruses. On the other hand, it often causes allergic reactions.

Differences between geneferon, kipferon and interferon

These drugs are derivatives of interferon. They have a similar effect on the human body and are used to treat various infectious diseases (urogenital inflammation, common viral or bacterial infections).

Genferon is the most effective immunostimulating drug against genital viruses (herpes, HPV). In the treatment of herpes, it has the advantages of pain relief and speeding up the healing of the rash. Kipferon - more effective for the treatment of intestinal viruses. Viferon - for the treatment of respiratory tract infections. In addition to the listed immunostimulants, there are many other drugs: Laferobion drops, Egiferon solution in ampoules, Lokfiron in the form of an injection solution, Diaferon ointment, Sveferon suppositories and a dozen more trade names and forms with the main active ingredient - interferon.

Instructions for use

Active ingredients

Release form

suppositories

Compound

In 1 suppository: Interferon human recombinant alpha-2 1 million IU. Taurine 10 mg. Benzocaine 55 mg. purified.

Pharmacological effect

Combined drug, the action of which is due to the components that make up its composition. It has a local and systemic immunomodulatory effect. Interferon alpha-2 has antiviral, antimicrobial and immunomodulatory effects. Under the influence of interferon alpha-2, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, increases. The activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and the restoration of the production of secretory immunoglobulin A. Interferon alpha-2 also directly inhibits the replication and transcription of viruses, chlamydia. Taurine has membrane and hepatoprotective, antioxidant and anti-inflammatory properties, enhances tissue regeneration. Benzocaine is a local anesthetic. Reduces the permeability of cell membranes for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, blocks the conduction of nerve impulses. Prevents the occurrence of pain impulses in the endings of sensory nerves and their conduction along the nerve fibers.

Pharmacokinetics

When administered vaginally or rectally, interferon alfa-2 is absorbed through the mucous membrane, enters the surrounding tissues, into the lymphatic system, providing a systemic effect. Also, due to partial fixation on the cells of the mucous membrane, it has a local effect. A decrease in the level of serum interferon 12 hours after the administration of the drug necessitates its repeated administration.

Indications

As part of complex therapy for infectious and inflammatory diseases of the urogenital tract: - genital herpes; - chlamydia; - ureaplasmosis; - mycoplasmosis; - recurrent vaginal candidiasis; - bacterial vaginosis; - trichomoniasis; - papillomavirus infections; - bacterial vaginosis; - cervical erosion; - cervicitis; - vulvovaginitis; - bartholinitis; - adnexitis; - prostatitis; - urethritis; - balanitis; - balanoposthitis.

Contraindications

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation

If it is necessary to use the drug in the II and III trimesters of pregnancy, the expected benefit to the mother and the potential risk to the fetus should be correlated.

Dosage and administration

In infectious and inflammatory diseases of the urogenital tract in women, the drug is prescribed intravaginally, 1 supp. (250 thousand or 500 thousand IU, depending on the severity of the disease) 2 times / day for 10 days. In chronic diseases, the drug is prescribed 3 times a week (every other day), 1 supp. within 1-3 months. In case of infectious and inflammatory diseases of the urogenital tract in men, the drug is prescribed rectally, 1 supp. (500 thousand-1 million IU, depending on the severity of the disease) 2 times / day for 10 days.

Side effects

Allergic reactions: skin rash, itching. These phenomena are reversible and disappear 72 hours after the dose is reduced or the drug is discontinued. When the drug is administered at a dose of 10 million IU / day, the risk of developing the following side effects increases. From the side of the central nervous system: headache. From the hematopoietic system: leukopenia, thrombocytopenia. Others : fever, increased sweating, fatigue, myalgia, loss of appetite, arthralgia.

Overdose

To date, cases of overdose of the drug Genferon have not been reported.

Interaction with other drugs

When combined with antibiotics and other antimicrobial drugs used to treat urogenital infections, the effectiveness of Genferon increases. When used simultaneously with vitamins E and C, the effect of interferon is enhanced. When used together with NSAIDs and anticholinesterase drugs, the effect of benzocaine is potentiated. When used together, antibacterial activity decreases sulfonamides (due to the action of benzocaine).

special instructions

The drug should be used with caution in patients with allergic and autoimmune diseases in the acute stage.

Suppositories Genferon Light

both dosages have a cylindrical shape, pointed at one end. It has a white or yellow-white color on the outside, the internal contents look uniform on the cut.

In some candles, an oblong-shaped air rod or a funnel-shaped depression may be visible on the cut. Genferon Light suppositories of both dosages (125,000 IU and 250,000 IU) are available in packs of 5 or 10 pieces.

The drug is available in the form of suppositories (candles) for vaginal or rectal administration. Suppository Genferon has the shape of a cylinder with a sharp end, painted white or slightly yellowish.

The inner surface of the suppository has a homogeneous structure. Sometimes an air rod or a small funnel-shaped depression is revealed on a suppository incision.

The drug Genferon of any dosage is available in packs of 5 or 10 suppositories by the domestic pharmaceutical company CJSC Biocad.

Suppositories are white or white with a yellowish tint, cylindrical in shape with a pointed end, uniform on a longitudinal section. An air rod or a funnel-shaped recess is allowed on the cut.

Candles have a cylindrical shape with a cone-shaped end of white or light beige color, with a longitudinal cut, the mass is homogeneous in its structure, although sometimes a small depression at the base is allowed.

They are available in three types:

1. 1 suppository containing active ingredients: interferon alpha-2b human recombinant - 250,000 IU; taurine - 0.01 g, benzocaine - 0.055 g; auxiliary components: dextran 60,000, macrogol 1500, polysorbate 80, T2 emulsifier, sodium hydrocitrate, citric acid, purified water, refractory fat, which does not cause local allergic reactions.
2. 1 suppository containing active ingredients: interferon alpha-2b human recombinant - 500,000 IU; taurine - 0.01 g, benzocaine - 0.055 g; auxiliary components: dextran 60,000, macrogol 1500, polysorbate 80, T2 emulsifier, sodium hydrocitrate, citric acid, purified water, refractory fats.
3. 1 suppository containing active ingredients: interferon alpha-2b human recombinant - 1,000,000 IU; taurine - 0.01 g, benzocaine - 0.055 g;

Auxiliary components: dextran 60,000, macrogol 1500, polysorbate 80, T2 emulsifier, sodium hydrocitrate, citric acid, purified water, refractory fats.

Recently, Genferon candles for children have been on sale in pharmacy chains under the name Genferon light. They are packed in foil plates and placed in a cardboard box, which prevents mechanical impact on the drug.

One plate contains 5 hermetically packed capsules, for easy opening there is a special incision. Each box contains two plates.

Genferon Light for children is well tolerated by babies, safe in infancy. The drug is prescribed by pediatricians in the complex treatment of acute respiratory viral infections.

Suppositories from white to white with a yellowish tint, cylindrical in shape, with a pointed end.

Warts are warty growths caused by the human papillomavirus. The carriers of this virus is half of humanity. In most cases, pink or flesh-colored formations are located on the genitals.

The active virus is not only on the genital mucosa. The causative agent was found in urine, saliva. The skin disease is extremely contagious. Genital warts are often located in groups, require careful study, timely treatment.

Causes of appearanceSymptoms and forms of the diseaseMethods of treating the diseaseMedicationsModern removal methodsFolk remedies and recipesPreventive recommendations

Reasons for the appearance

Warty formations appear as a result of the activity of HPV (human papillomavirus). The appearance of genital warts and papillomas causes several varieties of the virus.

The mechanism of action of Genferon

The pharmacological agent Genferon consists of alpha-2-interferon, anestezin and taurine:

1. Alpha-2-interferon - acts as a means to correct and stimulate the immune system. It provokes an increase in cellular immunity at the local level, and also helps to reduce the reproduction of viruses and bacteria by exposing them to immunoglobulin A.
2. Anestezin is a local drug that reduces the inflammatory response in the mucous membranes of the genital tract. With its action, pain, burning, itching in various diseases of the genitourinary system are significantly reduced.
3. Taurine is a drug that stimulates body tissues to regenerate and restore their function. This component is considered especially important in the treatment of mucosal erosions. Taurine helps to reduce the diameter of erosion and the growth of non-keratinized epithelial tissue.

In the drug Genferon, the above components are in the correct ratio, so the drug quickly and effectively fights the cause of the disease, affecting the human immune system.

Nosological classification (ICD-10)

- A49.3 Mycoplasma infection, unspecified - A56 Other sexually transmitted diseases of chlamydia - A59 Trichomoniasis - A60 Anogenital herpes virus infection - A63.8 Other specified diseases, predominantly sexually transmitted - B37.3 Candidiasis of the vulva and vagina (N77 .1)- B97.7 Papillomaviruses- N34 Urethritis and urethral syndrome- N41 Inflammatory diseases of the prostate gland- N48.1 Balanoposthitis- N48.6 Balanitis- N70 Salpingitis and oophoritis- N72 Inflammatory diseases of the cervix- N74.4 Inflammatory diseases of the female pelvic organs caused by chlamydia (A56.1) - N75.9 Bartholin gland disease, unspecified - N76 Other inflammatory diseases of the vagina and vulva - N86 Erosion and ectropion of the cervix

Use cases: children

Children under seven years of age are prescribed a drug in a lower dosage - "Light", which contains 125 thousand IU, exclusively by prescription. For older children, dosages of 250, 500 and 1000 thousand IU are allowed, in accordance with the severity of the disease.

The drug is most often prescribed in the treatment of acute respiratory viral infections, diseases of the genitourinary system, it is injected into the rectum one suppository once a day, preferably at bedtime.

The drug is prescribed in combination with antibiotics and vitamins, and although the immune system in a child acts a little differently than in an adult, contraindications for the use of "Genferon" in children are the same. With serious disorders in the functioning of the immune system, the drug has no significant effect.

Reviews about the treatment of children with "Genferon" are different, both positive and negative. When it comes to children under 7 years old, doctors most often prescribe a drug of a similar composition, developed taking into account the age-related characteristics of immunity.

Is Genferon used for children? Despite the novelty of the drug and medical disputes, geneferon is used to treat children from the first days of life. But only when necessary.

For example, a child is not able to recover, their own immunity is greatly reduced, the body cannot cope with an infection, or complex surgical treatment is necessary.

Do not use genferon suppositories to treat the common cold, cough or cold. Even for the treatment of influenza in children, geneferon suppositories are used only for a protracted course of the disease, when the immune system is severely weakened and the body is unable to cope with the virus.

Advice: in the treatment of children, the smallest concentration of the active substance is used - Genferon Light 125. Due to the minimum amount of interferon, the likelihood of an allergic reaction from the use of these suppositories is the least.

Instructions for use for children "Genferon" in certain forms of release can be used from infancy. A dosage of 125,000 IU is considered safe - this format of suppositories is prescribed for babies up to the age of seven.

From seven years and older, you can use candles containing 250,000 IU of active ingredients.

For children, the instructions for use "Genferon" is recommended as an element of the complex therapy of viral diseases (including SARS). Twice a day, a suppository is administered, maintaining semi-daily intervals between procedures.

The duration of the drug is five days. If, upon completion of such a course, the symptoms do not weaken or worsen, it is urgent to get an appointment with a qualified doctor.

In chronic foci of viral activity, "Genferon" is prescribed to children twice daily, observing breaks of 12 hours between procedures. At the same time, other means are used to stop inflammatory processes and infection.

With foci of infection, inflammation in the urogenital tract, with an acute form of the disease, "Genferon" is prescribed to children twice a day for a candle with a ten-day program. At the same time, they undergo a specific course of treatment at the discretion of the doctor.

Pregnancy and lactation

Spray Genferon Light

can be used by pregnant women and nursing mothers without restrictions, according to the usual dosages.

Suppositories Genferon Light. Today, the safety of using Genferon Light suppositories during pregnancy from 13 to 40 weeks, that is, the II and III trimesters of gestation, has been proven.

The effects on the woman's body and the fetus during pregnancy from 1 to 12 weeks have not been clarified. During experimental studies on animals, the safety of Genferon Light in relation to the fetus was revealed, but also a moderate increase in the risk of miscarriage in a woman.

Clinical studies have proven the safety of intravaginal use of the drug Genferon® 250,000 IU during pregnancy 13-40 weeks. The safety of the drug in the first trimester of pregnancy has not been studied.

If it is necessary to use the drug in the II and III trimesters of pregnancy, the expected benefit to the mother and the potential risk to the fetus should be correlated.

Like many other drugs, "Genferon" is prescribed to pregnant women only on the condition that the potential risk from its use will be significantly inferior to the benefits. The recommended dosage is 250 IU.

At the time of taking "Genferon", it is recommended that lactating women express themselves and temporarily transfer the child to artificial nutrition.

Use in the second half of pregnancy is allowed if the benefit of the therapy outweighs the possible risk to the fetus.

Therapeutic effects (principles of treatment)

Genferon is a combination drug - an immunomodulator, which is used primarily for the treatment of chronic inflammatory diseases of the genitourinary tract in men and women.

The therapeutic effects are provided by the active substances that make up its composition - interferon alpha 2b, taurine and benzocaine.

Effects of interferon

Recombinant human

alpha 2b is obtained by introducing a special gene into the bacterium Escherichia coli, which produces this substance. Human interferon alfa 2b has the following local and systemic effects:

• antiviral action;
• antibacterial action;
• immunomodulatory action;
• antiproliferative action (stopping the reproduction of pathogenic microorganisms).

Genferon has an antiviral effect by influencing specific

Which help stop the reproduction of viruses. In addition to the activation of enzymes, Genferon directly suppresses signals for the reproduction of a viral particle.

The antibacterial effect of the drug is achieved by activating the cells of the immune system, which begin to fight pathogenic bacteria more effectively.

Instructions for Genferon suppositories provide a list of infections in which the drug has a therapeutic effect:

• Herpes virus - more often used to treat the genital virus, but can also be used for oral and herpes zoster.
• HPV or human papillomavirus.

Genferon is one of the latest drugs to stimulate the immune system. In addition to the traditional interferon, it additionally contains taurine and an anesthetic.

The combined action of these components provide a therapeutic effect - suppositories help in the treatment of herpes and other genital infections. However, high concentrations often cause allergic reactions or side effects.

Hello readers! Today we will introduce you to one of the popular forms of the drug for the treatment of genital warts.

These are candles for genital warts, which can be rectal or vaginal, as well as aimed at different stages of the development of the disease.

Some of them increase immune protection, others have antiseptic properties.

What are candles?

As mentioned above, candles are rectal and vaginal. Rectal, in turn, can have a systemic effect or local, vaginal - always only local.

Which candles to use, and in what course, the doctor decides. There are suppositories with only antiseptic action, for example, Betadine, which are often prescribed vaginally for combined bacterial, fungal and human papillomavirus infections.

There are drugs that are used rectally, while having not only a local effect (antiseptic), but also systemic (antiviral and immunostimulating). These are Panavir, Genferon and Viferon.

The active substances of the drug are not only able to stop the development of infection, but also provoke their reverse development (involution).

Treatment of condylomatosis is usually long-term. Indeed, in addition to removing external manifestations, it is necessary to reduce the number of viruses in the body, otherwise relapses will immediately make themselves felt.

MORE ABOUT: Bacteriophages: types, purpose, instructions for use

To maintain the strength of your body, there are many means: this is proper nutrition, work and rest, reducing emotional stress, various folk recipes.

It is with the help of folk methods that you can effectively cleanse the body of toxins, remove annoying growths on the skin without visiting a doctor and using expensive procedures.

If you are interested in non-traditional treatment, you can read it in detail in this book. It contains a full course of treatment, thanks to which you will get rid of warts on any part of the body in 2-3 months.

Antiseptics

First of all, this is the well-known drug Betadine. Candles contain the active substance povidone-iodine, which is a broad-spectrum antiseptic.

It is not absorbed into the general circulation, it works only locally, while quite effectively inactivating fungi, bacteria, and viruses.

Candles are released for vaginal use. After their introduction, povidone-iodine comes into contact with the mucous membrane, forming active iodine, which neutralizes the infectious agent.

More often, Betadine is prescribed after surgical or chemical removal of genital warts, since it does not stimulate the body's defenses.

In parallel, the doctor prescribes drugs that can affect the immune system, we will talk about them later.

The use of suppositories is simple: they are administered after preliminary cleansing of the vagina (for example, by douching), once a day, usually at night.

The course of treatment is 2 weeks. Contraindications for use are hypersensitivity to iodine, impaired thyroid function, pregnancy up to 12 weeks, carefully during lactation, as well as patients with Dühring's dermatitis.

Immunostimulating drugs

Such drugs are mainly represented by antiviral Viferon, Genferon, Panavir.

The latter is available in the form of rectal and vaginal suppositories for genital warts, as well as other infections of a bacterial, viral, fungal nature.

Panavir contains 200 mg. active substance, acts as an antiviral and immunotropic substance. In the complex treatment of condylomatosis, Panavir is prescribed once every 3 days, or once every 4 days.

This is repeated three times. Candles also have a slight analgesic effect, they are administered once a day, at night, in a course of 5 days.

Genferon suppositories indirectly affect the human papillomavirus (there are both rectal and vaginal).

The main active ingredient is interferon-alpha, recommended for many infectious diseases in both men and women.

Kipferon belongs to domestic drugs that have an immunostimulating effect. The drug has both local and systemic effects.

The drug is prescribed rectally twice a day for 1 suppository. The course will be 10 days, a second stage of treatment is possible.

It is produced in the form of rectal and vaginal suppositories, it is combined: the first component is a complex immunoglobulin preparation, the second is human recombinant alpha-interferon 2.

The use of the drug showed good therapeutic results, relative safety and rare side effects.

It is widely used in the treatment of genital warts in gynecological practice. Regardless of which treatment you choose, remember that your partner must also undergo drug therapy at the same time.

Human papillomavirus is considered to be a sexually transmitted infection. In recent years, the number of infected and people with skin manifestations of the disease has increased significantly.

The virus is dangerous primarily by its ability to cause cancer, severe pathologies of the respiratory tract in newborns, in addition, patients are always embarrassed by a cosmetic defect, so most of them seek medical help in a timely manner.

Before treatment, be sure to consult with specialists! Follow our news, there is a lot of useful new information ahead.

drug interaction

The combined use of Genferon with

enhances the effectiveness of therapy for infectious and inflammatory diseases of the genitourinary tract.

Anticholinesterase drugs:

• physostigmine;
• galantamine;
• prozerin;
• armin;
• pyrophos;
• ezerin.

When used in conjunction with Genferon, they lose some of their effectiveness against pathogenic microorganisms.

With an increase in body temperature after taking the drug, a single use of paracetamol at a dose of 500-1000 mg is allowed.

GENFERON is most effective in combination with drugs (including antibiotics and other antimicrobials) used to treat urogenital diseases.

Non-narcotic analgesics and anticholinesterase drugs increase the effect of benzocaine. Benzocaine reduces the antibacterial activity of sulfonamides.

A complex appointment with antibiotics and antiseptics enhances the effect of "Genferon". Enhance the effect of benzene in the composition of non-steroidal anti-inflammatory drugs, such as Asprin, Baralgin, Diclofenac and others, as well as anticholinesterase drugs: for example, Prozerin, Eherin.

At the same time, "Genferon" reduces the effectiveness of sulfonamides.

Indications for use include complex therapy of infectious and inflammatory diseases of the urogenital tract:

1. prostatitis;
2. vulvovaginitis;
3. urethritis;
4. bacterial vaginosis;
5. erosion of the cervix;
6. mycoplasmosis;
7. cervicitis;
8. gardnerellosis;
9. ureaplasmosis;
10. trichomoniasis;
11. adnexitis;
12. bartholinitis.

Why do "Genferon" candles help yet? The drug is also prescribed for the treatment of:

• genital herpes;
• chlamydia;
• balanoposthitis;
• balanitis;
• recurrent vaginal candidiasis;
• papillomavirus infections.

It has no synonyms. Analogues have a similar effect:

1. Realdiron.
2. Intron A.
3. Altevir.
4. Oftalmoferon.
5. Grippferon.
6. Inferon.
7. Wellferon.
8. Alfaron.
9. Interferal.
10. Lifeferon.
11. Alfaferon.
12. Lokferon.
13. Reaferon-ES.
14. Interferon alpha-2 human recombinant.

Genferon is available in suppository form for rectal or vaginal administration. For children from zero to seven years, the composition of the drug includes IFN-alpha-2b 125000 IU and taurine 5 mg.

Since Genferon is an immunostimulating agent, it combines very well with other drugs (antibiotics or antimicrobials), while enhancing their therapeutic effect.

Analgesics and anticholinesterase drugs improve the action of geneferon. Thus, such drugs can be combined in order to increase the effectiveness of drugs.

However, before using them, you should consult your doctor. .

The use of "Genferon" with vitamins E and C, which accelerate the action of interferon, is shown.

In complex therapy, the drug is prescribed with other antimicrobial drugs or antibiotics. For example, it goes well with Terzhinan vaginal suppositories. They include:

• The antifungal agent nystatin
• Aminoglycoside antibiotic neomycin sulfate
• A substance of the imidazole group ternidazole, which works against anaerobic microorganisms, including Trichomonas and Gardnerella
• The corticosteroid prednisolone sodium metasulfobenzoate is a local anti-inflammatory agent.

"Terzhinan" with "Genferon" effectively interact with cystitis, thrush and other infectious diseases of the genitourinary system.

Another antiseptic that interacts well with Genferon is Hexicon. Its main active ingredient is chlorhexidine. "Hexicon" is produced in the form of vaginal suppositories and a solution. Effective against a number of infectious agents of various etiologies and locations.

Indications for use

Often, the drug is prescribed to women to reduce the risk of transition to a chronic form of inflammatory diseases of the genitourinary system and polyposis formations.

It is believed that polyposis formations are caused by the Epstein-Barr virus or other representatives of herpes viruses. If you fight viruses, the probability of the disappearance of polyps increases several times.

That is why polypous formations of the genitourinary system of a woman respond very well to treatment with Genferon vaginally. Gynecological diseases for which the use of this drug is recommended:

1. Herpes virus lesions of the reproductive system.
2. Chlamydial infection.
3. Inflammatory diseases caused by the ureaplasma group.
4. bacterial vaginitis.
5. Cervical erosion caused by infectious processes.
6. Bartholinitis.
7. Adnexitis.
8. Salpingoophoritis.
9. Cervicitis.

Among urologists-andrologists, Genferon is no less common. For men, the drug is prescribed rectally for inflammatory diseases of the rectum, prostate, urethra, glans penis.

Genferon is prescribed not only in gynecological hospitals, but also in outpatient treatment. The medicine is usually prescribed 2 suppositories per day vaginally with an interval of 12 hours.

The duration of treatment should be at least 10 days. During this time, the drug acts on viruses and bacteria, improves local immunity and has a powerful anti-inflammatory effect.

The use of the drug "Genferon suppositories" according to the instructions for use in gynecology provides a quick, long-term and effective counteraction to the disease of the human genitourinary system.

Among the reviews about the drug, the question is often found "Is it possible to use geneferon during menstruation?". The answer is definitely positive.

Genferon during menstruation reduces the possibility of reproduction of pathogenic pathogens. Bacteria in the presence of blood, a warm and humid atmosphere perceive such an environment as favorable for reproduction and growth.

The use of the drug "Candles Genferon" during menstruation prevents the reproduction of pathogenic microorganisms and helps to reduce inflammation in the mucous membrane of the female genital organs.

It should be noted that a pause in the use of the drug may adversely affect its effectiveness, since the effect of the drug gradually increases throughout the treatment.

Another feature of the use of the drug is its combination with other representatives of pharmaceutical products. It is noted that Genferon increases its positive qualities when combined with vitamins C, A, B.

In this case, vitamin complexes should be taken either in tablets or in injectable form.

The drug should be used only after the appointment of a specialist.

The drug can not be used in case of:

1. Severe allergic reaction to one of the components.
2. With pronounced changes in the parameters of platelets and leukocytes in a clinical blood test.

Is it possible to cope with a disease of the genitourinary system without Genferon?

The components of Genferon have a complex effect, providing antiviral, antibacterial, anti-inflammatory and immunomodulatory effects. Such a comprehensive approach will reduce the risk of acute inflammation becoming chronic, as well as significantly reduce the time of illness.

The use of the drug in chronic diseases will achieve a stable remission of the disease. The versatile effect of the drug allows it to be used for all kinds of diseases of the genitourinary system, which are accompanied by impaired immunity and the addition of an infectious pathology.

Methods of using the drug Genferon differ in men and women.

Scheme of application for women

Depending on the severity of infectious and inflammatory pathologies of the urinary and reproductive systems, the duration of their course, the severity of complaints, women need to use Genferon 250,000 IU, 500,000 IU or 1,000,000 IU.

Suppositories are administered twice a day into the vagina or rectum, depending on the location of the pathology (into the vagina with

genital tract, and in the rectum with inflammation of the urinary tract). Treatment is continued for at least 10 days.

In the presence of a long-term inflammatory disease of the genitourinary tract, after the main course of therapy lasting 10 days, it is necessary to continue taking Genferon for 1-3 months, one suppository every three days.

A severe infectious disease of the genital tract is allowed to be treated with a combination of Genferon suppositories with other suppositories that have antibacterial and antifungal properties.

In this situation, 1 suppository of Genferon 500,000 IU is injected into the vagina in the morning, and 1 suppository of Genferon 1,000,000 IU is injected into the rectum in the evening, and the second drug, with pronounced antifungal and antimicrobial activity, is injected into the vagina.

The course is 10 days.

In order to sanitize the vagina, normalize microbial biocenosis, treat sexually transmitted infections and inflammation of the genitourinary system, pregnant women can use Genferon 1 suppository 250,000 IU twice a day.

To do this, one suppository is introduced into the vagina in the morning and evening, for 10 days. Pregnant women can receive treatment between 13 and 40 weeks.

Scheme of application for men

For the treatment of infectious and inflammatory diseases of the urinary system and genital tract, men use Genferon suppositories in dosages of 500,000 IU and 1,000,000 IU, depending on the severity of the pathology, the duration of the disease and the severity of clinical

Genferon for men is administered rectally (into the rectum), one suppository twice a day, for 10 days.

Against the background of the use of the drug Genferon, vitamin therapy (B and C) can be used, which significantly increases the effectiveness of the drug.

Scheme of application for children

Children under 7 years of age can use the drug Genferon Light at a dosage of 125,000 IU, only on the recommendation of a doctor.

Children and adolescents aged 7–14 years can safely use Genferon suppositories at a dosage of 250,000 IU. Adolescents over 14 years of age can use the drug in any dosage (250,000 IU, 500,000 IU and 1000,000 IU), depending on the severity of the disease.

Genferon is most often used to treat acute respiratory viral diseases or urinary tract infections in children. Candles for children are administered exclusively rectally, that is, into the rectum.

Avoid the introduction of Genferon into the vagina in girls under 7 years of age, since the microflora of the child is not sufficiently developed and is not ready for exposure to aggressive chemicals.

So, for the treatment of acute viral infections in children, one suppository is administered into the rectum twice a day, for 5 days. If the disease is protracted or chronic, then the duration of treatment is extended to 10 days.

After the end of the course, in order to prevent the recurrence of a viral infection and strengthen the child's immunity, you can take one suppository rectally, in the evening, once every two days, for 1 to 3 months.

Treatment of diseases of the urinary system and genital organs in children is carried out using a 10-day course of rectal administration of the drug Genferon, one suppository twice a day. It is necessary to ensure that the interval between two injections of Genferon does not exceed 12 hours.

The use of the drug in children must be combined with the intake of vitamins A and C, as well as antibiotics and other drugs that can be used to treat viral or infectious-inflammatory pathologies.

Contraindications for the use of Genferon in children are similar to those for adults (autoimmune pathologies, allergic reactions). If an allergy develops, the drug should be stopped immediately.

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Overdose

An overdose of this drug has never been detected to date. However, in the situation of introducing a large number of suppositories at the same time, it is necessary to take a break in the reception for 24 hours, and after a day, continue treatment according to the scheme indicated by the doctor.

1. Infectious and inflammatory diseases of the urogenital tract in women.

1 suppository (250,000 IU or 500,000 IU or 1,000,000 IU, depending on the severity of the disease) vaginally or rectally (depending on the nature of the disease)

1 time per day daily for 10 days. With protracted forms 3 times a week every other day, 1 suppository for 1-3 months.

With a pronounced infectious and inflammatory process in the vagina, it is possible to use 1 suppository 500,000 IU intravaginally in the morning and 1 suppository 1,000,000 IU rectally at night, simultaneously with the introduction of a suppository containing antibacterial / fungicidal agents into the vagina.

To normalize the indicators of local immunity in the treatment of infectious and inflammatory diseases of the urogenital tract in women with a gestational age of 13-40 weeks, 1 suppository of 250,000 IU is used vaginally 2 times a day, daily for 10 days.

2. Infectious and inflammatory diseases of the urogenital tract in men.

Rectally 1 suppository (500,000 IU or 1,000,000 IU, depending on the severity of the disease) 2 times a day for 10 days.

To prevent urogenital reinfection, it is recommended to consider the simultaneous treatment of the sexual partner.

It is allowed to use the drug during menstruation.

The drug GENFERON® does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving vehicles, machinery, etc.).

This drug is used differently in men and women:

1. Women can use the drug both vaginally and rectally, depending on the location and nature of the disease, the duration of the course and the severity. Candles are administered twice a day, the course is 1.5 weeks, and in the presence of a strong inflammatory process - from 1 to 3 months. Sometimes the use can be combined - in case of a severe infectious disease, then, in addition to anti-inflammatory drugs, suppositories are used both vaginally and rectally, one suppository in the morning and evening. Pregnant women begin to be treated from 13 weeks after conception;
2. Men use "Genferon" rectally in dosages of 500 and 1000 thousand IU, depending on the severity and duration of the disease, suppositories are prescribed two per day, the course is up to 10 days.

Experts note that the parallel use of B and C vitamins improves the effect.

Suppositories are often prescribed in the treatment of diseases of the genitourinary system of infectious etymology in the second and third semesters. The bioactive components of the drug trigger enzymatic processes in the woman's body, which do not allow the virus to multiply, which improves the body's immune system.

"Genferon" is indicated for use in:

• trichomoniasis;
• thrush;
• herpes;
• ureaplasmosis, etc.

Usually the course is prescribed for 10 days, but if the disease is chronic, then the course will be longer.

"Genferon" (candles and spray) instructions for use prescribes the use of schemes depending on the gender and age of the patient.

Women

1 suppository intravaginally or into the rectum 2 times a day (depending on the severity of the disease of the organs of the reproductive and urinary systems, the severity of complaints and the duration of the course of the disease at a dosage of 250 thousand, 500 thousand or 1 million IU). The course of treatment is at least 10 days.

In the case of a long-term inflammatory disease of the genitourinary system, after the main course, it is recommended to continue treatment with Genferon for another 1 to 3 months, one suppository every 3 days.

To sanitize the vagina and normalize its microbial biocenosis, as well as to treat inflammation of the genitourinary system and sexually transmitted infections, pregnant women (for a period of 13 weeks or more) can use the drug 1 supp.

250 thousand IU 2 times a day for 10 days. With a shorter gestational age, you should refrain from taking the drug.

Men

1 suppository 2 times a day for 10 days (for the treatment of infectious and inflammatory diseases of the reproductive and urinary systems in dosages of 500 thousand or 1 million IU, depending on the nature and severity of the disease, the severity of clinical symptoms and the duration of the disease).

Spray application

At the first signs of the disease, Genferon Light spray is administered intranasally for 5 days, one dose (one click on the dispenser) in each nasal passage 3 times a day (one dose is approximately 50,000 IU of interferon alfa-2b, the daily dose should not exceed 500,000 IU ).

Upon contact with a patient with acute respiratory viral infections and / or with hypothermia, the drug is administered according to the indicated scheme 2 times a day for 5-7 days. If necessary, preventive courses are repeated.

Method of application for children

Candles "Genferon" - not a children's medicine. However, the instructions for use indicate that it is possible to use the suppository in the process of treating a child.

So, children under 7 years old can be prescribed suppositories at a dosage of 125 thousand IU. And for older children and adolescents (7-14 years old), candles of 250 thousand IU are prescribed.

Also, this dosage is indicated for children with severe and protracted ailments.

For infants and premature babies (8 months), it is optimal to prescribe suppositories with a dosage of 125 thousand IU twice a day, for 5 days. Premature babies born before 8 months are shown 1 candle of the same dosage every 8 hours (3 times a day), also for 5 days.

Such treatment courses can be duplicated if necessary. It is important to remember that for children under 14 years old, it is possible to enter suppositories only into the anus.

Avoid inserting the suppository into the vagina.

For children over 7 years of age, the instructions for use advise adhering to the following dosages of the drug "Genferon" 250 thousand IU.

• With viral inflammatory processes of an acute nature of various dislocations: 1 suppository 2 times a day, a course of 5 days
• With viral inflammatory processes of various dislocations of a chronic nature: 1 suppository (250 thousand IU) twice a day, for 10 days. The course also involves maintenance therapy (1-3 months). At this time, the child is administered 1 suppository every other day, preferably in the evening.
• For infections of the genitourinary system of an acute nature: 1 suppository (250 thousand IU) twice a day, for the next 10 days

Genferon light suppositories are prescribed by a pediatrician for children in the complex treatment of various acute respiratory viral infections and infectious diseases, acute viral respiratory diseases and those that are bacterial and viral in nature, in diseases associated with infectious inflammation of the urological-genital organs.

The rectal route of administration of the drug ensures its rapid absorption into the human body. Medicinal components enter directly into the bloodstream, and are not absorbed through the liver. This route of drug administration is gentle for children, as well as for people suffering from various liver diseases.

After a thorough examination of the child, a questioning of the parents, and also on the basis of the results of the blood and urine tests, the pediatrician may prescribe Genferon suppositories as a treatment for any disease.

Infants and up to seven years of age are prescribed a minimum dosage of 125,000 units, after seven years - 250,000 units.

Since the drug belongs to immunostimulating agents, it is especially effective in the initial stages of acute respiratory viral infections, chronic and other viral-inflammatory diseases, especially in acute form in children.

The drug is prescribed one suppository in the morning and evening, so that the time interval between taking the medicine is at least twelve hours. Most often, the course of treatment lasts from five to ten days.

In diseases of the urogenital organs and infectious inflammation in children, treatment with Genferon suppositories lasts ten days, twice a day with an interval of twelve hours.

The reception of "Genferon" is indicated for various infectious diseases, the causative agents of which are viruses, bacteria, protozoa, fungi. It is used to treat:

• Diseases of the male and female genital area caused by the herpes virus, HPV (human papillomavirus), gardnerella, mycoplasma, ureplasma, chlamydia, trichomonas, candida and other microorganisms
• Colds - acute respiratory infections and acute respiratory viral infections, acute bronchitis, etc.
• Diseases of the urinary tract, in particular, bacterial chronic cystitis.

Read about the dangers of diseases of the genitourinary system in the article: Causes and treatment of burning sensation during urination in men and women.

Candles are administered vaginally or rectally, depending on the gender of the patient, the nature of the disease and the prescribed therapy.

For the treatment of diseases of the genitourinary system, women are prescribed 2 times in 12 hours, one suppository with a dosage of 500 thousand IU or 1000 thousand IU. As a rule, this is a vaginal administration.

The duration of treatment is up to 10 days. In the treatment of the chronic form of the disease, 1 suppository is used three times a week, with an interval of one day, for 1-3 months.

You can use candles during menstruation.

In acute infectious inflammation of the female genital tract, complex therapy is used:

1. In the morning vaginally Genferon 500 thousand IU
2. In the evening Genferon 1000 thousand IU rectally and additionally vaginal suppositories with an antibacterial effect (for example, Hexicon).

Men, in particular "Genferon" for prostatitis, are shown to use suppositories rectally twice a day, with a dosage of 500,000 or 1,000,000 IU, depending on the severity of the disease. Use the drug for no longer than 10 days.

Under the supervision of a doctor, you can use "Genferon" for children, with different dosages, depending on the age of the patient:

• 1-7 years old - a pediatrician may prescribe Genferon Light (125,000 IU)
• 7-14 years - the dosage is increased to 250 thousand IU
• Over 14 years old - dosages similar to adults: 250 thousand IU, 500 thousand IU, or 1,000,000 IU, depending on the severity of the disease.

Candles, which are slightly smaller than usual, are injected into the rectum after 12 hours. Duration of admission - 5 days. If the child has a relapse of a chronic disease or the disease has taken a protracted form, the doctor may add another 5-day course of treatment.

It is possible to use the drug for prophylactic purposes: one suppository at night, every other day. Preventive use of the drug is from 1 to 3 months.

During pregnancy and breastfeeding

When deciding whether to use "Genferon" for the treatment of pregnant women, the doctor must balance the benefits for the mother to the harm that can be done to the child.

The drug is prescribed no earlier than the 12th week of pregnancy. This drug is used in systemic therapy for detected ureaplasma, thrush, herpes virus, HPV, cystitis and other viral and bacterial diseases.

"Genferon" is not prescribed during lactation.

Depending on the purpose of therapy, the methods of using the drug also differ somewhat. The main points in the treatment of women are as follows:

• standard scheme- one suppository in the vagina twice a day for ten days (for gynecological diseases and genital infections);
• evening candle - if necessary (if there are other suppositories), you can lay it rectally;
• with recurrent processes- after the main treatment, it is necessary to lay one candle for three months;
• in diseases not related to the genital organs- suppositories should be inserted rectally;
• during menstruation– should be switched to rectal use.

Men and children should use one suppository in the rectum in the morning and evening.

Nasal spray "Genferon" is used in men, women and children after 7 years - twice a day, one injection for the prevention and treatment of colds.

Infectious and inflammatory diseases of the urogenital tract in women. 1 supp. (250,000 or 500,000 IU, depending on the severity of the disease) intravaginally 2 times a day, daily for 10 days. With protracted forms 3 times a week every other day, 1 supp. within 1-3 months. Infectious and inflammatory diseases in men. Rectally, 1 supp. (500,000 or 1 million IU, depending on the severity of the disease) 2 times a day for 10 days.

Allokin alfa is a Russian-made antiviral drug. Effective against herpes and HPV. Good reviews among doctors and patients - up to 98% cure. Producer: FMBA of Russia

A doctor's prescription is required to purchase.

Indications

Allokin-alpha showed itself well in the following viral infections:

• Human papillomavirus, especially its oncogenic types (read detailed information about HPV)
• Herpes virus types 1 and 2
• Hepatitis B virus
• flu virus

Allokin alfa is available in ampoules, in powder form. The box may contain 1, 2, 3, 5 or 10 ampoules. One ampoule - one injection. Not available in tablets.

The use of Genferon suppositories is indicated for the complex therapy of infectious and inflammatory diseases, which include:

• Infections of the urogenital tract in women or girls - chlamydia, genital herpes, vaginal candidiasis, mycoplasmosis, ureaplasmosis, trichomoniasis, bacterial vaginosis, cervical erosion or inflammation (cervicitis), adnexitis, bartholinitis.
• Infectious and inflammatory pathology of the urogenital tract in men - balanitis, balanoposthitis, urethritis.
• Chronic inflammation of the bladder (chronic cystitis).
• An acute inflammatory process in the mucous membrane of the bronchi - acute bronchitis.

Such therapy allows you to increase the functional activity of the immune system. Intravaginally, the drug can be used for pregnant and lactating women.

An absolute contraindication to the use of Genferon suppositories is individual intolerance or hypersensitivity to the active substances or auxiliary components of the drug.

It is used with caution in case of exacerbation of concomitant allergic pathology. Before using Genferon suppositories, you need to make sure that there are no contraindications.

Candles Genferon are used by introducing them into the rectum (rectal administration) or into the vagina in women (intravaginal administration). Dosage and course of treatment are determined by the underlying pathology:

• Infectious-inflammatory pathology of the urogenital tract in women - depending on the severity of the course of the pathological process, 250,000 or 500,000 IU intravaginally 2 times a day. A combination of intravaginal (morning) and rectal (evening) administration of suppositories is also possible. The duration of the course of therapy averages 10 days.
• Infectious-inflammatory pathology in men - Genferon suppositories are administered rectally (150,000 or 500,000 IU, depending on the severity of the pathological process) 2 times a day, 7-10 days.
• Complex therapy of acute bronchitis in adults - suppository 1000000 IU 2 times a day rectally for 5 days.
• Chronic cystitis - with a relapse (exacerbation) of the inflammatory process 1,000,000 IU 2 times a day rectally. Then, to prevent relapse, 1 suppository (1,000,000 IU) is used every other day for 40 days.

If necessary, the dosage and duration of the course of treatment can be adjusted by the attending physician.

Indications

Since the range of therapeutic properties of Genferon is quite large, it has found wide application in the complex therapy of various inflammatory diseases of the genitourinary system in men and women.

Genferon is used both as an independent drug and as part of complex therapy using non-drug methods.

An absolute contraindication to the use of the drug Genferon is the presence of sensitivity or

Exacerbation of allergic and autoimmune diseases.

Hypersensitivity to the components of the drug.

"Genferon" is widely used as a component of therapy in the development of inflammatory processes of the genitourinary system in both sexes.

Spray and candles "Genferon" instructions for use prohibits if the patient has:

• allergic reactions to one of the components of the drug;
• pregnancy up to 12 weeks;
• autoimmune diseases (type I diabetes mellitus, systemic lupus erythematosus, Hashimoto's thyroidin, glomerulonephritis and others);
• exacerbation of allergic conditions.

For the drug geneferon, the instruction does not regulate any contraindications. However, for interferon (the main active ingredient in suppositories), the list of contraindications is quite wide. It is not recommended to be treated with drugs with interferon for the following diseases:

• Disorders of the heart, liver, kidneys.
• Disturbances in the central nervous system (namely, epilepsy).
• Diseases of the thyroid gland (with a diseased thyroid gland, interferon can cause hyperthyroidism).

Candles genferon are not prescribed if the child has an individual intolerance to the individual components and components of the drug. There are no contraindications for autoimmune and allergic diseases, however, for persons belonging to this category, the drug is prescribed with caution.

It is forbidden to use candles under the following conditions: the first trimester of pregnancy and an individual allergic reaction to the substances that make up it.

Candles "Genferon" should not be used in case of hypersensitivity to any component of the drug, as well as in case of ever recorded allergy to analogue drugs. From rectal use, it is necessary to refrain from exacerbation of hemorrhoids.

Contraindications for use are autoimmune diseases, since the drug can compromise the exacerbation or progression of ailments. For example, with autoimmune thyroiditis, glomerulonephritis, diabetes mellitus, scleroderma.

"Genferon" during pregnancy is allowed only from 12 weeks according to indications. Data on the safety of use is not previously available. For the time of use during lactation, it is recommended to stop breastfeeding.

As part of complex therapy for infectious and inflammatory diseases of the urogenital tract: - genital herpes; - chlamydia; - ureaplasmosis; - mycoplasmosis; - recurrent vaginal candidiasis; - bacterial vaginosis; - trichomoniasis; - papillomavirus infections; - bacterial vaginosis; - cervical erosion; - cervicitis; - vulvovaginitis; - bartholinitis; - adnexitis; - prostatitis; - urethritis; - balanitis; - balanoposthitis.

Individual intolerance to interferon and other substances that make up the drug.
With caution - exacerbation of allergic and autoimmune diseases.

Price

The average cost of 10 suppositories Genferon Light 125,000 IU is 213 - 310 rubles, while the price of 10 suppositories Genferon Light 250,000 IU ranges from 274 to 380 rubles. Spray for injection into the nose Genferon Light 50,000 IU is sold at an average price of 257 - 302 rubles.

Candles Genferon can be purchased at a pharmacy or through an online store. The manufacturer recommends dispensing the drug by prescription, but Genferon can often be purchased without a doctor's prescription.

The price may be different, and depends on the pharmacy chain's markup, transportation costs, etc. Since Genferon is produced by CJSC Biocad, there is no difference between a cheaper and more expensive drug.

So, the average price for 10 Genferon suppositories 250,000 IU is 310 - 415 rubles. The cost of 10 suppositories of Genferon 500,000 IU is on average 402 - 539 rubles, and the price of 10 pieces of Genferon 1,000,000 IU ranges from 552 to 700 rubles.

The well-known analogue of "Genferon" - "Viferon", is based on the same active substance - interferon alpha 2b. Experts see the main difference between these two drugs in that they have a different effect on fungi of the genus Candida, i.e. suppress them with varying degrees of effectiveness.

The price of "Genferon" is from 350 to 500 rubles.

The average price of "Genferon" (candles 500 thousand IU No. 10) in Moscow is 428 rubles. In Kyiv, you can buy medicine for 303 hryvnia, in Kazakhstan - for 975 tenge. In Minsk, pharmacies offer "Genferon Light" (suppositories 125 thousand IU No. 10) for 8-9 bel. rubles. It is released from pharmacies by prescription.

The cost of the drug is from 155 to 277 rubles.

The average cost of Genferon candles in Moscow pharmacies depends on the dosage:

• 250,000 IU - 260-287 rubles.
• 500,000 IU - 384-414 rubles.
• 1000000 IU - 526-566 rubles.