Candles Terzhinan from thrush. Instructions for use, indications, composition, price. High efficiency of terzhinan suppositories in the fight against female diseases

Combined vaginal tablets. Four active components effectively fight the cause of the disease, enhancing each other's action. After the start of treatment, unpleasant symptoms in patients are quickly eliminated. It is active against bacteria, protozoa and fungi. It is not absorbed into the systemic circulation, so it can be prescribed to pregnant and lactating women.

Dosage form

Many patients know the drug Terzhinan as suppositories, but in fact its dosage form is called vaginal tablets. They have an oblong shape, light yellow color and punctate inclusions in their structure. The letter "T" is printed on both sides of the medicine. The manufacturer produces packages of 6 and 10 tablets, which are exactly the same in composition. The choice of packaging and the number of tablets depends on the expected duration of the course of treatment.

Description and composition

Terzhinan is a combination drug, which consists of four main active ingredients:

1. Ternidazole. The dosage in 1 tablet is 200 mg. The substance exhibits a fairly broad activity against the most common pathogens of gynecological diseases. It has antibacterial, antitrichomonas, antiprotozoal action, and also has a detrimental effect on anaerobic microorganisms.
2. neomycin sulfate. A broad spectrum antibiotic that effectively kills Gram-positive and Gram-negative pathogens. Each tablet contains 100 mg of this substance.
3. . An antifungal antibiotic that is detrimental to fungi of the genus. It is necessary to suppress activity, including to prevent complications after antibiotic therapy. The dosage in Terzhinan is 100 thousand IU.
4. Prednisolone salt (in terms of pure substance 3 mg/tablet). Belongs to the group of steroid hormones. The component helps to reduce the severity of symptoms and alleviate the patient's condition. exhibits anti-inflammatory, antipruritic and desensitizing effects. If the remaining components are necessary to fight the infectious agent, then this substance is added to Terzhinan to provide symptomatic therapy.

During clinical trials, women noted an improvement in well-being already on the 2nd-3rd day of treatment with Terzhinan. The drug was effective in various diagnoses and successfully relieved itching, burning and other discomfort in patients. Terzhinan showed good results both in the treatment of allergic diseases and in inflammatory processes after mechanical damage.

An important positive point is the ability of the drug to restore the balance of the vaginal microflora, maintain a constant pH and stimulate the processes of mucosal regeneration.

When applied topically, the components are not absorbed into the systemic circulation, so their effect extends only to the lesion.

Pharmacological group

Terzhinan refers to combined antimicrobial agents for topical use in gynecology.

Indications for use

for adults

Terzhinan is prescribed for the treatment of infectious gynecological diseases:

1. Bacterial.
2. Trichomoniasis.
3. Candidiasis.
4. mixed etiology.

In addition, Terzhinan can be used to prevent urogenital infections and inflammatory processes in the following cases:

1. A few days before gynecological operations.
2. On the eve of childbirth or abortion.
3. During the installation of the intrauterine device.
4. Before and after cervical treatment.
5. before hysterography.

for kids

It is intended for the treatment of gynecological diseases, therefore it is not used in children.

A high safety profile, lack of toxicity and systemic action makes it possible to use Terzhinan during pregnancy and lactation. The indications for this category of patients correspond to the general indications for adults.

Contraindications

Of the contraindications, the manufacturer indicates only hypersensitivity to the main or auxiliary components of the drug.

Applications and doses

for adults

Terzhinan tablets are intended for intravaginal administration only. To properly place the tablet in the vagina, this must be done in the supine position. The procedure is carried out at night to prevent leakage of the drug and ensure maximum contact with the mucosa. Before administration, the tablet is moistened in water for approximately 20 seconds and inserted with a finger as deeply as possible.

If the doctor has increased the frequency of administration up to two times a day, then after the daily procedure it is recommended to lie down for at least 15 minutes.

The course of treatment can be 6 or 10 days, depending on the doctor's prescription. In chronic forms of diseases, the duration can be increased up to 20 days.

During menstruation, treatment is not stopped.

for pregnant women and during lactation

Treatment occurs according to the general scheme of administration. Pregnant and lactating women are categorically not recommended to exceed the doses of Terzhinan prescribed by the doctor.

Side effects

Despite the strong components in the composition of Terzhinan, adverse reactions are rare, since the effect of the drug is limited to the injection site. Some patients may complain of local discomfort, itching, burning sensation. In some cases, individual allergic reactions are possible, which require discontinuation of the drug.

Interaction with other drugs

In clinical trials, the interaction of Terzhinan with other drugs has not been identified.

special instructions

Sexual infections require mandatory treatment of both partners. For a man, the doctor selects another drug for oral administration.

For the duration of treatment, it is desirable to exclude sexual intercourse, especially since it can damage latex contraceptives.

Of all the components of Terzhinan, slight absorption is possible in. More careful monitoring by doctors requires patients who additionally take steroid hormones orally.

Terzhinan does not affect the speed of reactions and concentration of attention, therefore it is allowed for use by drivers.

Overdose

With the standard regimen, absorption of the drug is negligible and overdose is unlikely. Exceeding doses can cause an increase in local side effects, which requires symptomatic treatment and discontinuation of the drug.

Storage conditions

Does not require special storage conditions. Permissible temperature regime - 25 degrees.

Analogues

Instead of Terzhinan, the following drugs can be used:

1. Giterna is a combined Russian drug, which is a partial analogue of Terzhinan. It is produced in vaginal tablets, which can be used to treat genital infections in women in position and breastfeeding.
2. - a combined medication that is available in vaginal capsules. The therapeutic effect of it is explained by neomycin, and polymyxin. The drug is not allowed in the first trimester and during breastfeeding.
3. Elzhina is a combination drug that has antibacterial, antimycotic and antiprotozoal effects. It is produced in vaginal tablets, which are not allowed for patients under 18 years of age, pregnant and lactating.
4. Amintax is a domestic drug used in gynecology. It is a partial analogue of the drug Terzhinan. Medicines are produced in capsules that need to be inserted into the vagina. They are contraindicated during and breastfeeding.

The price of the drug

The cost of the drug is an average of 441 rubles. Prices range from 320 to 746 rubles.

Terzhinan, the instructions for the use of which must be strictly observed, is used in the gynecological field. In indications for the appointment - vaginitis of various types.

The drug has a fairly high efficiency.

Terzhinan vaginal tablets are characterized by the following action:

• antibacterial;
• anti-inflammatory;
• antiprotozoal;
• antifungal.

The drug owes its high efficiency to the following components included in its composition:

• Ternidazole. It is able to eliminate a number of anaerobic bacteria, among which is gardnerella.
• neomycin sulfate. An effective antibiotic that has a wide range of effects.
• Nystatin. Antibiotic with high antifungal activity.
• Prednisolone. Has an anti-inflammatory effect.

In addition to the main ones, excipients are included in the composition of vaginal suppositories.

The composition of the drug helps to maintain a normal pH in the vagina.

Indications

Indications for the use of Terzhinan suppositories are as follows:

• bacterial vaginosis caused by an infection;
• bacterial inflammation of the vagina;
• vaginal candidiasis (thrush);
• nonspecific vaginitis;
• gardnerellosis;
• vaginitis caused by Trichomonas.

Assign vaginal suppositories in the following cases:

• prophylaxis before surgery;
• prevention of complications after surgery;
• various methods of artificial termination of pregnancy and the period before childbirth;
• use of the IUD (intrauterine device).

The main advantage of using Terzhinan tablets is that they act on pathogenic microorganisms, destroying them, but at the same time do not violate the natural microflora of the vagina.

Terzhinan: instructions for use

If Terzhinan tablets are prescribed, the instructions for use must be followed exactly. It is recommended to insert one vaginal tablet or suppository into the vagina once a day, before going to bed. If the drug is used during the daytime, then after the administration of the drug, you need to lie down for about 20 minutes.

For more convenient administration, the tablet should be held in water for about 20 seconds before use.

The duration of treatment is 10-20 days, recommendations are given by the attending doctor. During menstruation, therapy does not stop.

If the drug is prescribed for prevention purposes, then the duration of the treatment course is about 7 days.

During pregnancy

Terzhinan during pregnancy is prohibited for use in the first trimester. On the 2nd and 3rd trimester, admission is possible, but only according to the testimony of the attending doctor and under his control.

The use of the drug during breastfeeding is possible if the benefit to the woman significantly outweighs the risk to the child. But this question is also decided only by a doctor.

Contraindications

Candles Terzhinan are contraindicated for admission only if the woman has an individual intolerance to the individual components of the drug.

Side effects

According to reviews, side effects are rare. Women mostly point to local reactions.

The manufacturer indicates the following as side effects:

• burning in the vagina;
• irritation;
• symptoms of an allergic reaction.

Price

Pharmacies offer Terzhinan vaginal tablets in packs of 6 pieces and 10 pieces.

Average price:

• packing of 6 tablets - from 310 rubles;
• pack of 10 tablets - from 420 rubles.

Analogues

The analogues of Terzhinan include the following drugs:

• Pimafucin (vaginal suppositories, 6 pieces) - from 250 rubles;
• Polygynax (vaginal capsules, 6 pieces) - from 299 rubles;
• Clotrimazole (vaginal tablets, 6 pieces) - from 12 rubles;
• Meratin Combi (vaginal tablets, 10 pieces) - from 1500 r.

The most effective analogue is Polygynax, which contains three antibiotics. Of the shortcomings - only its ineffectiveness in the treatment of trichomoniasis.

In the treatment of vaginosis caused by Trichomonas with Terzhinan, parallel treatment of the sexual partner is recommended. During sexual intercourse during therapy, it is necessary to use barrier contraceptives or completely abandon intimate relationships.

With or candidiasis after the completion of the course, it is necessary to pass repeated tests. A complete recovery can only be judged if there are appropriate examination results.

The drug should be prescribed only by a doctor. Self-medication is not allowed. The wrong choice of dosage, insufficient duration of the therapeutic course can lead to complications and the transition of the disease to the chronic stage.

On the drug video

There are many good medicines in the world, but the vast majority of them have more or less pronounced restrictions for taking, contraindications, and side effects. To the greatest extent, this applies to the means used inside. But local preparations are not without drawbacks - for example, among candles for the treatment of inflammatory processes in gynecology, it is not easy to choose a medicine that can be advised in almost all cases without fear of consequences. Terzhinan, which doctors often prescribe to their patients, meets the highest reliability criteria. Why is he so good?

The action of terzhinan

Terzhinan vaginal tablets, produced by the French pharmaceutical company Laboratoires Bouchara-Recordati, contain several antimicrobial components.

Tinidazole affects the so-called anaerobes - bacteria that live in anoxic conditions. This substance copes with many pathogens, including difficult to eradicate Trichomonas, for the sake of getting rid of which patients were previously supposed to drink unsafe metronidazole.

The next antibacterial agent, neomycin, covers the remaining spectrum of pathogenic bacteria, which makes the drug effective for any non-specific cause of infection, including infection with mixed flora.

Eliminates colonies of fungi, prednisone suppresses inflammation, relieves swelling and itching. Also, the product is supplemented with clove and geranium oils, which have an antiseptic and anti-inflammatory effect, and also have a restorative effect on the mucous membrane.

When and how to apply the medicine

The drug is effective:

- with vulvovaginitis, vaginitis and colpitis of non-specific origin, including those that appeared after an exacerbation of genitourinary infections;

- to prevent infection before surgery, childbirth, medical manipulations (cauterization of the cervix, setting the intrauterine device).

Evaluating the results of using the drug from a medical point of view, we can say that terzhinan is really effective both as a means of prevention and as a drug for the treatment of inflammation. Most patients describe its action as good, excellent, or nothing more, nothing less, excellent. Of course, it is also captivating that there are practically no prohibitions on the use of terzhinan: the drug acts exclusively locally, so patients may not be afraid of side effects associated with the penetration of its components into the blood.

It is very simple to treat with this remedy, you need to inject 1 tablet into the vagina every night for 10 days (as prescribed by the doctor - longer) every night. Before this procedure, the tablet should be held in water for half a minute so that it becomes softer and can dissolve, and after it you should lie down for several minutes.

Terzhinan during pregnancy

This remedy causes women much less concern than or even completely safe. Among a fairly large selection, it is often preferred to everyone else. And rightly so: the drug has something to “please” patients who have reason to fear for their own and not only their health.

So, the benefits of terzhinan for pregnant women are as follows:

- it does not accumulate in the body and does not cause effects on the child. Having established its low absorption, scientists were even “too lazy” to conduct pharmacokinetic studies, that is, to study its chemical transformations inside the body: it was not possible to find significant traces of the drug in the blood.

- its efficiency is close to 100%. Some women have difficulty choosing a remedy for "difficult" germs such as Trichomonas. But terzhinan works on the widest possible spectrum. Its component tinidazole, a safe “relative” of the dangerous metronidazole, significantly expands the range of therapeutic action of the drug, but it does not penetrate the mother’s body and does not pass through the placenta to the child.

- In the West, studies have been conducted that study the tolerability and effect of the drug in pregnant women at different times. In 2004, similar tests were carried out in our country, and twice as many patients participated in them than in Europe. Based on our results, it was included in the national guidelines for the treatment of urinary tract infections in pregnant women. Focusing on maximum safety, in Russia it is advised to use it from the second trimester - which is unusual, given that abroad it is used throughout the entire period.

The most frequent questions of patients

• When using the drug the next day, a slight burning sensation appeared. How to evaluate it?

In rare cases, transient discomfort may occur at the beginning of treatment with terzhinan. It will disappear in 2-3 days.

• The course is scheduled for 10 days, but in its second half, menstruation should begin. Should I stop treatment?

Not worth it, you need to continue therapy for the required time.

• Along with inflammation, the doctor found erosion and prescribed local treatment for it. Is it possible to use terzhinan together with sea buckthorn suppositories?

It is possible, the components of terzhinan do not interact with other drugs. But, if possible, it is desirable to divide the use of different means by 1-2 hours.

• After treatment with terzhinan, there was a delay in menstruation. Is it somehow related to the drug?

Terzhinan does not contain hormonal components, so it cannot affect the menstrual cycle, you need to look for other causes of the violation.

• There was vulvovaginitis, a course of treatment with terzhinan was carried out. The drug helped, but after a short time the symptoms reappeared. And this is not the first time ... What to do?

If a similar situation is created, then the infection occurs again. It is advisable to examine and treat the sexual partner, for this he should contact a urologist.

Perhaps, the use of terzhinan does not need further explanation. The main thing you need to know is that it is one of the safest and preferred treatments for gynecological problems. However, if you have any other questions, contact your doctor - he will definitely clarify the points of interest for you.

Terzhinan - suppositories with antiprotozoal, antibacterial, anti-inflammatory and antifungal effects for topical use in gynecology. Additionally, the drug relieves the inflammatory process, maintains the pH level and restores the structure of the vaginal mucosa.

Combined drug for topical use in the treatment of gynecological pathologies. Indications for the use of Terzhinan suppositories are colpitis, vaginitis and vaginosis caused by various pathogens sensitive to the active ingredients of the complex medication.

The effectiveness of the drug is associated with the following properties:

- anti-inflammatory;
- antimycotic (antifungal);
- antiprotozoal;
- antibacterial.

The action of the drug is due to the properties of its constituent components.

Release form and composition

Light yellow vaginal tablets. Terzhinan contains several active components:

- ternidazole - 200 mg;
- nystatin - 100 thousand IU;
- prednisolone - 3 mg;
- neomycin sulfate - 100 mg.

• Tinidazole affects the so-called anaerobes - bacteria that live in anoxic conditions.
• Nystatin is a substance with antifungal properties, especially active against fungi of the genus candida.
• Prednisolone sodium metasulfobenzoate is a corticosteroid agent with a local anti-inflammatory effect. Prednisolone suppresses inflammation, relieves swelling and itching.
• Neomycin sulfate is an aminoglycoside antibiotic that acts on pyogenic bacteria of the vagina.

The active active ingredients of Terzhinan vaginal suppositories are included in concentrations that cause a synergistic, enhancing effect of individual ingredients, thus expanding the range of action on the microflora of the pathogenic nature of the vagina, without affecting the natural microflora.

The advantages of intravaginal administration of the Terzhinan complex preparation are the effect only on the diseased organ, ease of use, minimal risk of side effects, the absence of irritating effects on the mucous membrane of the stomach and intestines, which are observed during therapy with tablets and capsules intended for oral administration.

Candles Terzhinan do not contain hormonal components, so they cannot influence the menstrual cycle. A big plus of this remedy is that it does not disturb the natural balance and death of beneficial microflora, as, for example, after antibiotic treatment. Therefore, after a course of therapy, there is no need to drink lactobacilli to restore the vaginal microflora.

Indications for use Terzhinan

• bacterial vaginitis caused by banal pyogenic microflora;
• trichomoniasis of the vagina;
• vaginitis caused by fungi of the genus Candida and mixed infection;
• prevention of vaginitis.

Prevention of urogenital infections / vaginitis, including:

• before gynecological operations;
• before childbirth or abortion;
• before and after the installation of the IUD;
• before and after diathermocoagulation of the cervix;
• before hysterography.

Terzhinan is also used as a means of preventing complications of antibiotic therapy.

The combined preparation in combination with complex therapy, in the shortest possible time, relieves the symptoms of irritation, itching and relieves inflammation.

Instructions for use of candles Terzhinan, dosage

The optimal duration of the course of therapy is no more than 10 days. In the case of diagnosed mycosis, the duration of use can be increased up to 20 days. The total duration of prophylactic use of Terzhinan is 6 days. Dosage - one candle Terzhinan per day.

Apply intravaginally. A vaginal suppository is inserted deep into the vagina in the "lying" position before going to bed. Before the introduction of the candle should be held in water for 20-30 seconds. After the introduction, you need to lie down for 10 - 15 minutes.

Application features

If pathogenic microorganisms are found in you during sowing, you need to treat your permanent sexual partner. During the treatment of diseases of an infectious nature, both sexual partners must undergo treatment with Terzhinan, otherwise the infection will resume after sexual contact.

The drug is well tolerated, the only thing that doctors sometimes forget to warn about, and women, as a rule, pay little attention to the official instructions for using Terzhinan attached to the medication - the candle must be held in water for several seconds before being inserted into the vaginal cavity.

For the course of treatment, it is desirable to choose a period when menstruation is absent.

Candles Terzhinan can also be used during breastfeeding, all active components of the product do not enter breast milk.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms. Does not affect.

There are no data on the effect of ethanol on the body during therapy with Terzhinan intravaginal suppositories.

Side effects and contraindications Terzhinan

In rare cases, transient discomfort may occur at the beginning of treatment with terzhinan. It will disappear in 2-3 days.

Cases of exacerbation of side effects are isolated and are expressed by local reactions in the form of a burning sensation when the suppository is administered, or by allergic manifestations on the skin. In such cases, the use of Terzhinan candles should be replaced with a more gentle analogue.

Overdose

Due to the slight adsorption and penetration into the general circulation, the possibility of an overdose is unlikely.

With a significant excess of the dose of the drug Terzhinan, an increase in adverse reactions is possible.

Contraindications

A contraindication to the use of Terzhinan is hypersensitivity to the main and auxiliary components of the drug.

Terzhinan is contraindicated in the first trimester of pregnancy. In the second and third trimester, for nursing mothers, the drug should be prescribed only by a doctor.

Terzhinan vaginal suppositories are not intended for the treatment of patients under 16 years of age.

Analogues Terzhinan, list of drugs

Analogues of Terzhinan vaginal suppositories are drugs list):

1. Meratin Combi
2. Neotrizol.

Please note: instructions for the use of Terzhinan suppositories, price and reviews of analogues do not apply and cannot be used as a guide to dosage or replacement of the drug. Any change in the prescribed treatment regimen must be agreed with the doctor - this is important!

Attention! Adjustment of the daily dose must be agreed with the gynecologist.

Terzhinan - an updated description of the drug, you can read contraindications, side effects, prices in pharmacies for Terzhinan. Useful reviews about Terzhinan -

Combined preparation for local use in gynecology.
Preparation: TERZHINAN
The active substance of the drug: comb. drug
ATX encoding: G01BA
CFG: Antibacterial, antiprotozoal, antifungal and anti-inflammatory drug for topical use in gynecology
Registration number: P No. 015129/01
Date of registration: 21.07.08
The owner of the reg. Award: Laboratoires BOUCHARA-RECORDATI (France)

Tablets for vaginal use
1 tab.
ternidazole
200 mg
neomycin sulfate
100 mg
nystatin
100 thousand units
prednisolone
3 mg

Excipients: corn starch, lactose, anhydrous silicon dioxide, talc, magnesium stearate, sodium lauryl sulfate, povidone, fragrance.

6 pcs. - cellular contour packings (1) - packs of cardboard.
10 pieces. - cellular contour packings (1) - packs of cardboard.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action Terzhinan

Combined preparation for local use in gynecology. The action of the drug is due to the properties of its constituent components.

Ternidazole - an imidazole derivative - has a trichomonacid effect, is also active against anaerobic bacteria, in particular Gardnerella spp.

Neomycin sulfate is a broad-spectrum antibiotic from the group of aminoglycosides.

Nystatin is an antifungal antibiotic from the group of polyenes, highly active against fungi of the genus Candida.

Prednisolone is a glucocorticoid that has a pronounced anti-inflammatory effect.

The composition of the excipient ensures the integrity of the vaginal mucosa and the constancy of pH.

Pharmacokinetics of the drug.

Studies of the pharmacokinetics of the drug Terzhinan were not conducted due to low systemic absorption.

Indications for use:

Treatment of vaginitis caused by microorganisms sensitive to the drug:

bacterial vaginosis;

Bacterial vaginitis caused by banal pyogenic or conditionally pathogenic rod microflora;

Trichomoniasis of the vagina;

Vaginitis caused by fungi of the genus Candida;

Mixed vaginitis.

Prevention of vaginitis:

Before gynecological operations;

Before childbirth or abortion;

Before and after the installation of the IUD;

Before and after diathermocoagulation of the cervix;

before hysterography.

Dosage and method of application of the drug.

Assign 1 vaginal tablet / day at bedtime. The average duration of the course of therapy is 10 days; in case of confirmed mycosis, it can be increased up to 20 days. Do not stop treatment during menstruation.

Before insertion into the vagina, the tablet should be held in water for 20-30 seconds.

Side effects of Terzhinan:

Local reactions: rarely - burning sensation, local irritation (especially at the beginning of therapy).

Other: extremely rare - allergic reactions.

Contraindications to the drug:

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation.

It is possible to use Terzhinan during pregnancy and lactation (breastfeeding) according to indications.

Special instructions for the use of Terzhinan.

It is necessary to conduct simultaneous treatment of the sexual partner because of the risk of re-infection.