Panangin how much. What the experts say. Is it worth taking Panangin for prophylactic purposes?

Panangin has a number of trace elements necessary for the body - the instructions for use indicate that it is used for convulsions, high blood pressure, a decrease in myocardial contractility and vascular spasms caused by the influence of potassium and magnesium in insufficient quantities. Their stock and replenishes this drug. Potassium and magnesium are contained in the drug in an easily digestible form, so it is highly effective. Their combination is due to the fact that the lack of one of the elements is often accompanied by a shortage of the other.

The basis of the drug are 2 trace elements - magnesium and potassium ions. Due to them, the medicine normalizes the heart rhythm, further improving the conduction of the nerve impulse through the conduction system of the heart. Restoring the level of ions by eliminating the deficiency of magnesium and potassium helps with heart rhythm disturbances. Such effects help in the treatment or prevention of atherosclerosis, myocardial infarction. Panangin - instructions for its use indicate that it is part of a combination therapy against the onset of arrhythmia or chronic heart disease.

Compound

Regardless of the form of release, the main substances of the drug are potassium and magnesium. The composition contains auxiliary components. They are different for tablets and solution, in the form of which the drug is produced. The table describes the composition in more detail:

Release form

Panangin is available in different forms - in the form of a solution for injection and tablets for oral administration. The active substances in them are the same, but are contained in different concentrations. In a pharmacy, each form of the drug can be recognized by the special packaging and the type of tablets or solution themselves:

Pharmacodynamics and pharmacokinetics

Magnesium and potassium are very important for the formation of bonds between macromolecules and intracellular structures, the preservation of myocardial functions, and muscle contraction. Substances help:

• restore electrolyte balance;
• regulate metabolic processes and reactions;
• prevent the development of arrhythmia due to low levels of potassium and magnesium.

Potassium is an integral part of synaptic transmission, the implementation of muscle contractions. Its asparaginate improves nerve impulse conduction. Additionally, the trace element has a diuretic effect. Magnesium is part of the reactions and processes responsible for energy expenditure. It promotes the penetration of potassium ions into the cells. A medicine based on them improves myocardial metabolism. According to the instructions for use, the drug is well absorbed and excreted by the kidneys.

Indications for use

The main indication for use is to replenish the deficiency of potassium and magnesium in the body. This is necessary for cardiovascular pathologies or the development of their complications. Specific indications, according to the instructions, are:

• heart failure;
• hypomagnesemia and hypokalemia with a low magnesium content or a lack of potassium in the diet;
• taking laxatives and diuretics, glucocorticosteroids;
• persistent vomiting, diarrhea;
• taking saluretics that increase the excretion of sodium;
• acute myocardial infarction;
• digitalis intoxication;
• atrial extrasystole;
• paroxysmal tachycardia;
• supraventricular tachycardia;
• ventricular extrasystole.

Method of application and dosage

The dosage of the drug is prescribed by the doctor, taking into account the disease and the nature of its course. Tablets are taken orally, and the solution is prescribed intravenously in the form of droppers. The latter method is used for a faster effect of the drug due to the fact that it enters the body, bypassing the digestive system. After some time, the Panangin solution is stopped, and therapy is continued by oral administration of the tablet form of release.

Tablets Panangin

The drug is prescribed orally 2 tablets up to 3 times a day. Maintenance therapy has a different dosage. As a preventive measure, it is recommended to take 1 tablet 3 times a day for up to 3-4 weeks. Sometimes a repeat cycle of therapy is required, but only a specialist can decide this. You need to take the medicine after eating, because the lack of food in the stomach reduces the therapeutic effectiveness of the drug.

This form of the drug is intended for slow infusion of a solution of about 20 drops per minute. The dosage is 1-2 ampoules diluted with 50-100 ml of glucose or 5% dextrose. Panangin - instructions for use in this form allows you to combine it with other drugs for intravenous administration. A second dropper is placed 4-6 hours after the first infusion.

special instructions

The drug is poorly compatible with alcohol, because it is used in the treatment of the cardiovascular system. For this reason, at the time of treatment, it is important to give up any kind of alcohol. Judging by the reviews, with the simultaneous use of alcohol and Panangin, vasospasm may occur. Before starting therapy, the doctor should be warned about taking any other medications. The drug does not affect the functional state of the cerebral cortex, therefore it does not change the speed of psychomotor reactions and concentration of attention.

Panangin for children

The dosage of the drug for children is slightly different. Intravenously, it is 10 ml of Panangin, diluted with 100 ml of a 5% glucose solution. The dosage of tablets is determined by the age of the child. It is 0.5 or 1 tablet, sometimes divided into 2-3 doses. According to the instructions, the drug is allowed even for newborns, but only the doctor determines the dosage in this case.

drug interaction

When taken with other antiarrhythmic drugs, Panangin enhances their dromotropic and bathmotropic effects. Anesthetics increase the inhibitory effect on the central nervous system. Taking Panangin with atracuronium, decamethonium and succinyl chloride leads to increased neuromuscular blockade. Astringent or enveloping medicines can reduce the absorption of potassium and magnesium. Panangin improves the tolerability of cardiac glycosides, as it is pharmaceutically compatible with their solutions. Other cases of interaction:

• calcium preparations reduce the therapeutic effect of Panangin;
• while taking potassium-sparing diuretics, heparin, cyclosporine, beta-blockers and ACE inhibitors, the risk of developing hyperkalemia increases;
• when taking Panangin, the effectiveness of streptomycin, polymyxin B, neomycin, tetracycline decreases.

Side effects

Judging by the reviews of cardiologists and patients, the result of the use of Panangin in some cases may be adverse reactions. They arise from different systems of the body. In general, these are the following side effects:

1. In relation to the cardiovascular system - paradoxical reactions, AV blockade.
2. On the part of digestion - discomfort in the epigastric region with antacid gastritis and cholecystitis, diarrhea, nausea, vomiting.
3. Water-electrolyte reactions - reddening of the skin of the face, hyperkalemia, hypermagnesemia, confusion, thirst, pressure drop, respiratory depression.

Overdose

If the recommended dosage of the drug is exceeded, side effects may not only increase, but other negative reactions that harm the body may also occur. In this case, hemodialysis or peritoneal dialysis and the emergency administration of a dextrose solution and sodium chloride are justified. Reactions after an overdose are:

• slowing atrioventricular conduction;
• muscle hypotension;
• changes in the electrocardiogram;
• paresthesia of the limbs;
• cardiac arrest.

Contraindications

The medicine has a large list of restrictions, so before using it, be sure to read the instructions. There are several common cases for both forms of release of the drug, but each of them has a number of individual contraindications. The table describes them in more detail:

Terms of sale and storage

You can buy Panangin in any form of release without a prescription from a doctor. It is necessary to store the medication in a dark place where it will not be accessible to children. The recommended temperature is 15-30 degrees Celsius. The shelf life of the drug is 5 years.

Panangin's analogs

There are drugs that are similar in composition or mechanism of action. Any analogue of Panangin has such characteristics, among which the following stand out.

• Magnesium Aspartate;
• Potassium Asparaginate;
• Biolectra Magnesium Fortissimum.

Panangin price

In specific pharmacies, Panangin costs differently. The price is determined not only by the place of purchase, but also by the manufacturer, dosage and form of release. The approximate cost of the drug is shown in the table:

Video

The composition of the tablets

Active substances: magnesium aspartate (140 mg) and potassium aspartate (158 mg).

Additional substances: silicon dioxide, corn and potato starch, talc, povidone, magnesium stearate. The shell consists of talc, macrogol 6000, titanium dioxide, methacrylic acid copolymer.

Concentrate for solution (Panangin IV)

pharmachologic effect

What is the cure for? It is a source of potassium and magnesium. The drug promotes recovery electrolyte balance , regulates metabolic, metabolic reactions and processes, has a pronounced antiarrhythmic effect. Potassium is actively involved in synaptic transmission , in the conduction of a nerve impulse through the fibers, in the implementation of muscle contractions, supports the normal functioning of the heart. With impaired potassium metabolism, the excitability of muscle tissue and nerves changes. Active ion transport maintains a high potassium gradient across the plasma membrane. Small doses of potassium contribute to the expansion of the coronary arteries, and in large doses, the trace element narrows their lumen. Potassium has a moderate diuretic effect , negative bathmotropic and chronotropic influence. Magnesium is a cofactor of three hundred enzyme reactions. Magnesium is an indispensable element in the course of processes and reactions that provide energy intake as well as expenditure. Magnesium is included in the pentose phosphate structure of DNA, takes part in the process of cell division and growth, the structure of heredity, RNA synthesis; is a natural BMCC, prevents the release of free fatty acids, catecholamines during stress, promotes the penetration of potassium ions into the cell. The drug has a stimulating effect on the intercellular synthesis of phosphates.

Mnn: potassium and magnesium aspartate.

Pharmacological group: potassium and magnesium preparation.

Pharmacodynamics and pharmacokinetics

Active substances play an important role in the formation of bonds between macromolecules, as well as intracellular structures and the mechanism of muscle contraction, myocardial metabolism.

According to the annotation, the drug is well absorbed. Excreted through the kidneys.

Indications for Panangin's use

Panangin tablets - what are they from?

Indications for the use of Panangin are as follows. The drug is prescribed for hypomagnesemia, hypokalemia , when taking laxatives and diuretics, glucocorticosteroids, with diarrhea, persistent vomiting, taking saluretics, with myocardial infarction, heart failure , digitalis intoxication, ventricular extrasystole , atrial extrasystole, supraventricular tachycardia, paroxysmal tachycardia.

An example of a recipe in Latin: Rp.: Dragee "Panangin" N. 20

Contraindications for Panangin

The drug is not used for intolerance to fructose, sorbitol, impaired metabolism, chronic pathology of the renal system, hemolysis, exicosis, dehydration, arterial hypotension , myasthenia gravis, hypermagnesemia, hyperkalemia, metabolic acidosis , Addison's disease. Panangin during pregnancy is used with caution.

Side effects

Side effects are the following manifestations: ulceration of the mucous wall of the digestive tract, pain in the epigastrium, bleeding from the digestive system, falling, bradycardia, a paradoxical reaction in the form of an increase in the number of extrasystoles, dry mouth, nausea, hyporeflexia, dyspnea, thrombosis, phlebitis, paresthesia, dizziness, increased sweating, asthenia , myasthenia. With rapid intravenous infusion, hypermagnesemia, hyperkalemia are noted.

Application instruction of Panangin (Way and dosage)

Tablets Panangin, instructions for use

How to drink medicine? The drug is taken orally three times a day, 2 tablets. Supportive and prophylactic therapy: three times a day, 1 tablet, course for 3-4 weeks. In some situations, a repeat course of therapy is required.

Instructions for use intravenously

Panangin's solution is administered intravenously by drip, slowly. The drug is administered at a rate of 20-30 drops per minute 1-2 times a day, 300 ml. Dosing of the drug Panangin during pregnancy is carried out according to the standard scheme for the use of the drug.

Children can take medicine from birth.

How to take Panangin for prevention?

If you ask yourself the question of the benefits and harms of Panangin, you should realize that this is a drug that has its own side effects, so you should not use it for prevention. Firstly, in this way you accustom the body to a high content of magnesium and potassium, and secondly, you can provoke an excess of these substances, which in turn can cause a lot of negative reactions.

Overdose

Manifested muscle hypotension , hyperkalemia, slowing down atrioventricular conduction , cardiac arrest, arrhythmia , paresthesia of the extremities, changes in the electrocardiogram. An emergency intravenous infusion of a solution of dextrose, sodium chloride is required. If necessary, peritoneal dialysis is justified.

Interaction

Panagin is able to enhance the negative bathmotropic, dromotropic effects antiarrhythmic drugs . The drug eliminates hypokalemia, which develops against the background of long-term use of diuretics, glucocorticosteroids, ISS. NSAIDs, ACE inhibitors, heparin, potassium-sparing diuretics, beta-blockers increase the risk of hyperkalemia. When using general anesthetics, the inhibitory effect of Panangin on the nervous system is enhanced. Succinyl chloride, decamethonium, atracuronium, suxamethonium enhance neuromuscular blockade . The use of enveloping and astringent medicines reduces the absorption of potassium and magnesium in the digestive tract. In combination with insulin, dextrose as part of the polarizing mixture, the heart rhythm normalizes in case of an overdose of cardiac glycosides, with ectopic arrhythmias,. Panangin improves tolerance cardiac glycosides , pharmaceutically compatible with their solutions.

Terms of sale

Does not require a prescription.

Storage conditions

In a place inaccessible to children at a temperature of 15-30 degrees Celsius.

Best before date

Not more than 5 years.

Panangin's analogs

Coincidence in the ATX code of the 4th level:

Alcohol compatibility

The drug is poorly compatible with alcohol, if only because the drug is usually used for problems with the heart and vascular system, and alcohol in these cases should be excluded. However, that's not all. With the simultaneous use of these substances, vasospasm may occur.

Reviews about Panangin

Reviews about Panangin on the forums are mostly positive. Buyers mark the drug as really effective, the drug facilitates the work of the heart, removes convulsions, really helps. It is noted as good pills for the heart.

Reviews about Panangin during pregnancy are as follows: the drug is often prescribed by doctors and is quite effective, despite the fact that in the description of the drug it is recommended to use the remedy with caution during this period.

Panangin price

The price of Panangin in tablets is 130 rubles, the price in ampoules is 160 rubles.

How much do pills cost in St. Petersburg? You can buy them at a cost of 125 rubles.

The price of Panangin is in Ukraine 120 and 130 UAH per tablet and solution, respectively.

• Internet pharmacies in Russia Russia
• Internet pharmacies of Ukraine Ukraine
• Internet pharmacies of Kazakhstan Kazakhstan

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Panangin (conc.d / solution 10ml No. 5)

Panangin forte

Panangin

Panangin is a drug manufactured by the Hungarian company Gedeon Richter, one of the most popular and inexpensive means to restore potassium-magnesium balance and strengthen the heart muscle.

Release form and composition

Panangin is available in two forms - in tablets (15 tablets are packaged in one blister, there can be 50-60 tablets in total) and an injection solution (one plastic ampoule contains 10 ml of solution, 5 ampoules in a package).

Tablets. Panangin has two active substances - magnesium aspartate (a derivative of aspartic acid) and potassium aspartate; the tablet contains 140 mg of the first and 158 mg of the second. In addition to the active substances, the tablets contain auxiliary ones - corn and potato starch, talc, magnesium stearate, povidone, colloidal silicon dioxide. Tablets are white, convex on both sides, odorless and coated.

Injection drug. It contains 40 mg of magnesium aspartate and 45.2 mg of potassium aspartate, as well as distilled water. The drug is transparent, it can be either colorless or light greenish.

How Panangin works

Electrolyte imbalances are a common problem. It is especially important to control the concentration of elements such as potassium and magnesium; in their predominant form, they are inside the cell in the form of positively charged ions (K +, Mg 2+) and take part in enzymatic processes (including energy utilization by the human body) and, at the molecular level, muscle contractions, help maintain acid-base balance and participate in the synthesis of many important elements for the body. The balance and concentration of these ions directly affects the contraction of the heart muscle. With potassium deficiency, the cardiovascular system is most at risk, in which pathologies can develop, in some cases can lead to death. Also, a violation of the potassium-magnesium balance can worsen the course of hypertension and increase the risk of stroke.

At the same time, both elements work in tandem - magnesium helps the body absorb potassium and maintains its concentration in the cells of the human body at a sufficient level. Therefore, it is better to take potassium and magnesium together. Aspartate also acts as a conductor of ions of active substances, delivering them inside the cell.

Pharmacokinetics

The drug is well absorbed, excreted by the kidneys.

Indications for Panangin's use

As a rule, Panangin is prescribed for magnesium and potassium deficiency, which can cause many causes - for example, severe infectious diseases, dehydration due to unforeseen circumstances or excessive enthusiasm for diuretic drugs and laxatives, after blood transfusion, due to various metabolic disorders and, of course, the lack of these substances in the diet. Panangin also helps the body to better perceive the medicinal effect of cardiac glycosides - drugs used to treat heart failure. Often Panangin is used in recovery from heart attacks, as well as in violation of the heart rhythm.

How to use Panangin

Orally. Panangin is taken in tablets one or two pieces three times a day. The maximum dose of the drug is 3 tablets 3 times a day. Tablets are taken after meals, the usual course of administration is two weeks. Although, according to the instructions, Panangin can be taken for as long as you like, it is recommended to discuss the duration of the medication and the need for repeated courses with your doctor.

If for some reason the patient missed taking Panangin, the pill should be taken immediately. However, if there is little time left before the next dose of the medicine, it is recommended to follow the schedule. You should not take a double dose of tablets.

Intravenously. For intravenous injections, a solution is used - the contents of the ampoule are mixed with 50-100 ml of a five percent glucose solution. The injection is carried out by a doctor or nurse by slow infusion - with the gradual introduction of the drug, the rate of increase in its concentration is lower, it is better absorbed by the body and there are no undesirable side effects in the form of skin flushing. The maximum dosage is two ampoules at a time; a break between doses of Panagina from 4 to 6 hours.

Is it worth taking Panangin for prophylactic purposes?

If there are no contraindications to the use of Panangin, and due to certain conditions (for example, with limited nutrition), potassium / magnesium in the diet is not present in sufficient quantities, Panangin can be taken as a preventive measure. If nutritional conditions are normal, blood levels of potassium and magnesium can be restored by including more honey, apple cider vinegar, bananas, dried fruits, nuts, green leafy vegetables, baked potatoes in their skins, legumes, rye bread and other foods rich in these elements in your diet.

Contraindications

Taking Panangin in some diseases can worsen the patient's health or adversely affect the absorption of the drug. Therefore, when contacting a doctor, it is necessary to warn him in advance about the presence of the following diseases:

Heart disease, such as arrhythmia, heart failure, atrioventricular block I-III degree. Myocardial infarction. Hemolysis.

Acute and chronic renal failure.

Disturbances in the balance of substances, such as hyperkalemia and hypermagnesemia, amino acid metabolism disorders, dehydration, metabolic acidosis.

Some autoimmune diseases such as severe myasthenia gravis.

Addison's disease.

Low blood pressure (cardiogenic shock). Although Panangin can be taken with moderate hypotension, however, with systolic blood pressure below 90 mm Hg. Art. it is recommended to abandon the drug.

Diseases of the urinary system, for example, anuria and oligonuria.

Increased sensitivity. If a person is allergic to any component of the tablets, it is recommended to refrain from taking Panangin.

Children under 18 should not take Panangin - its effect has not been tested on patients of this age.

Side effects

Taking Panangin can cause the following side effects:

The cardiovascular system. Decreased blood pressure, paradoxical reaction (sharp deterioration), atrioventricular heart block.

Muscular system. Paresthesia (burning, tingling, "goosebumps"), convulsions, hyporeflexia (decrease in reflexes, mainly spinal).

Gastrointestinal tract. Vomiting, nausea, feeling of heaviness in the pancreas, especially in patients with gastritis or cholecystitis.

Respiratory system. Respiratory depression.

Violation of potassium-magnesium metabolism. Hyperkalemia, the symptoms of which are general weakness, tachycardia, decreased muscle tone. Hypermagnesemia, which causes flushing of the face, increased thirst, low blood pressure, respiratory depression, convulsions.

Not all side effects that Panangin can cause are listed here; in many ways, their presence is due to the individual reaction of the body. If it seems to a person that taking Panangin causes any unpleasant changes in his body, you should consult a doctor.

special instructions

Hypotension. Preparations containing potassium and magnesium reduce blood pressure by about 3-5 mm Hg. Art., therefore, with low blood pressure, it is recommended to regularly monitor your performance.

Hyperkalemia. If Panangin is prescribed to a patient with hyperkalemia, it is necessary to constantly monitor the content of potassium ions using ionograms.

Pregnancy and breastfeeding. Clinical studies on the effect of Panangin on pregnant and lactating women have not been conducted, so it is recommended to use the drug very carefully, especially in the first trimester.

drug overdose

In case of an overdose of the drug, you should immediately consult a doctor, as potassium-magnesium imbalance can cause heart failure. If the following symptoms are observed: heart rhythm disturbance, chest pain, weakness, cold sweat, rare pulse, you should immediately seek emergency medical help.

Interaction of Panangin with other drugs

Co-administration of Panangin with other drugs may affect its effectiveness or increase the risk of side effects. It is recommended that when contacting a doctor, make a list of all medicines that the patient uses, including medicinal herbs and dietary supplements. Also, during the course of treatment with Panangin, you should not start taking any new medications or change the dosage of old ones without consulting a doctor.

Anesthetic agents. With the combined use of both Panangin and anesthetics (for example, atracuronium, dicamethonium, succinyl chloride and suxamethonium), neuromuscular blockade may increase.

Antiarrhythmic drugs. Panagin may contribute to the risk of side effects with these medicines.

Vitamin D. Calcitriol (which is converted into vitamin D in the kidneys) can increase the amount of magnesium in the blood plasma.

Potassium-sparing diuretics (eg, triamterone, spironolactone). Perhaps the development of hyperkalemia.

Tetracycline, neomycin, polymyxin B, streptomycin. When taken together and Panangin, and these drugs, a decrease in the level of action of the latter is observed.

Drugs of the group of beta-blockers and ACE-I. Although Panangin is not forbidden to be taken together with drugs of these groups, however, when taken together, the risk of developing hyperkalemia, a condition caused by an increased content of potassium in the blood, increases. In severe cases, hyperkalemia requires urgent medical attention, as it causes heart rhythm disturbances. If the doctor prescribes joint intake of these drugs, it is necessary to constantly monitor the level of potassium in the blood.

Preparations containing calcium. Reduce the effectiveness of drugs containing magnesium, including Panangin.

Preparations with astringent and enveloping effect. Difficult absorption of Panangin in the form of tablets; therefore, they should be taken separately with an interval of at least three hours.

Interaction of Panangin with alcohol

It is undesirable to combine Panangin with alcohol, since alcoholic drinks lower blood pressure and cause dehydration. The consequences can be up to a spasm of blood vessels and respiratory depression, therefore, in chronic alcoholism, Panangin is prescribed only in remission.

Terms of sale

Panangin is sold without a prescription.

Storage conditions

It is best to store Panangin at room temperature (15° to 25°), away from direct sunlight and low humidity; therefore, it is not recommended to keep Panangin in the refrigerator or in a cabinet in the bathroom. And, of course, the drug should be kept out of reach of children and pets.

Best before date

The drug can be stored for five years.

Panangin price

On average, the price of Panangin in tablets ranges from 150 to 170 rubles, an injection solution - from 160 to 180 rubles.

Panangin's analogs

The following medications have a similar composition and principle of action to Panangin: Asparkam, Asparkam-L, potassium and magnesium asparaginate Berlin-Chemie, Aspangin, Asparkad and so on.

Normally, the human body receives all the elements necessary for its full-fledged life from the food consumed. However, in some cases, the nutrients coming from food are not enough. In this case, various medicinal formulations come to the rescue, which are vitamin-mineral complexes. So, with certain problems with the cardiovascular system, a person may experience a deficiency of magnesium and potassium. To replenish their normal amount, you can consume a drug such as Panangin. Well, what is the use of Panangin for human health, you will now find out.

What is the composition of the drug Panangin?

The main active ingredients of this medication are magnesium aspartate, as well as potassium aspartate. Elements such as potassium and magnesium are intracellular cations, they play an important role in the full interaction of intracellular structures, as well as macromolecules. They take an active part in the work of many enzymes, as well as in the mechanisms of muscle contraction. In the event that a deficiency of these particles is observed in the body, metabolic changes may develop in the myocardium, in addition, arrhythmia occurs and arterial hypertension may appear.

Asparginate is not only an excellent carrier of magnesium and potassium ions, it also ensures their optimal penetration into cells.

The combination of potassium and magnesium in the medicinal composition of Panangin is explained by the fact that the lack of one of these elements is often accompanied by a deficiency of the other, so it is worthwhile to simultaneously correct such a shortage.

What is the purpose of Panangin?

The drug can be prescribed to a patient who has had a myocardial infarction, as well as to those who suffer from disturbances in the heart rhythm (as part of a complex effect). It is prescribed for chronic heart diseases, as well as in parallel with the consumption of cardiac glycosides. An indication for the consumption of Panangin is also /magnesium.

Is Panangin harmful??

The tablet form of Panangin cannot be prescribed to people with impaired amino acid metabolism, as well as in severe myasthenia gravis. This medicine is not indicated if the patient has first degree AV block. In addition, contraindications include dehydration, hemolysis and an acute form of metabolic acidosis.

In addition, internal consumption and intravenous administration of Panangin cannot be carried out in acute and chronic types of renal failure, hypermagnesemia and hyperkalemia. It is forbidden to use it in cardiogenic shock, when blood pressure drops below ninety millimeters of mercury, as well as in AV blockade, both second and third degree. Such use of Panangin is not possible with Addison's disease, oliguria, anuria and the presence of hypersensitivity to any of the components of this drug.

With special care, the medicinal composition is used during pregnancy and during breastfeeding, and infusion administration - with first-degree AV blockade.

How to take Panangin?

The tablet form of the drug can be used in the amount of one or two pieces three times a day. In this case, consumption should be carried out only after a meal, due to the fact that the acidic environment in the stomach significantly reduces the effectiveness of the drug. The maximum daily dose is nine tablets - three pieces three times a day.

The duration of therapy, as well as the possibility and feasibility of repeated courses of treatment, is determined solely by the doctor, who focuses on the patient's condition, type of disease, as well as on the individual characteristics of the patient.

The solution for intravenous administration is used with a dropper. In this case, one or two ampoules are considered to be a single dose. To make an infusion solution, dissolve the contents of the container in a five percent glucose solution (fifty to one hundred milliliters). Re-introduction can be carried out after about four to six hours.

How to replace Panangin?

Medicinal formulations such as Asparkam (different types), Potassium and magnesium asparaginate, as well as Panangin's substitute, Pamaton, have a similar composition and effect. Before replacing your prescribed medication with an analogue, you must always consult with your doctor.

Features of use

In certain cases, the consumption of Panangin can provoke the development of a number of side effects. So with accelerated intravenous administration, the patient may develop hypermagnesemia or hyperkalemia. The consumption of the tablet form of the drug sometimes leads to a decrease in blood pressure, the development of AV blockade and a paradoxical reaction. The central and peripheral nervous system may respond to medication with paresthesia, convulsions, and hyporeflexia. Panangin can lead to nausea, vomiting, diarrhea and discomfort in the pancreas. Sometimes there may be respiratory depression. If side effects occur, it is advisable to report them to your doctor.

At the same time, the Panangin annotation indicates that its use cannot interfere with driving, as well as performing any activity that requires concentration and speed of reaction, which is important in many cases.

Conclusion

You now know why Panangin is prescribed. However, the use of this medicinal composition must be carried out only after a doctor's prescription, although the drug can be purchased at a pharmacy without presenting a prescription.

For those who take Panangin, instructions for use are required to read. Even if the attending physician has explained everything, you need to familiarize yourself with the information provided. Panangin refers to drugs containing easily digestible potassium and magnesium, which are needed to nourish and strengthen the muscles of the heart. The doctor prescribes this remedy not only to those who have a disease of the cardiovascular system, but also to a healthy person for prevention. However, this is done if there are prerequisites. It is not worth it to prescribe Panangin on your own, uncontrolled use will not bring benefits, and in the worst case, even harm. You should be careful about contraindications and side effects.

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General information about the drug

Manufacturers produce Panangin in several forms: in the form of tablets and a solution. The liquid intended for intravenous administration is colorless and odorless, a transparent greenish tint is allowed. When looking at the contents in the solution, no grains should be found. The preparation contains 45.2 mg of potassium aspartate per 1 ml of liquid.

The drug is packaged in a plastic shell, five ampoules. To reduce the cost of production, cardboard packaging is used. In the drug, which is available in the form of tablets, the color ranges from white to white with a tint. All tablets are covered with an enteric film, from which the appearance of the drug is shiny and uneven.

The tablets contain particles of corn starch, talc, potato starch, magnesium stearate, povidone, silicon dioxide. For the film coating of the tablet, talc, titanium dioxide, macrogol 6000 are used. Tablets are packaged in a bottle of 50 pieces and packed in cardboard boxes.





Pharmacological properties

According to the pharmacological properties, Panangin has an effect on the patient's metabolism. At low levels of potassium and magnesium ions, a person experiences a number of pathogenic processes. This is expressed both in problems with the myocardium and in the development of atherosclerosis of the coronary artery. It even reaches arterial hypertension, which is dangerous to health. At the same time, Panangin can be attributed to the sources of magnesium and potassium compounds, and it can protect the body from the consequences of a lack of these elements.



From the imbalance of potassium in the cells, the production of toxicity of cardiac glycosides occurs, myocardial contractility decreases, tachycardia and arrhythmia appear. Magnesium contained in Panangin has an anti-ischemic effect on myocardial tissue, which stimulates coronary blood flow.

The presence of magnesium and potassium in Panangin at the same time is explained by the fact that most often the body suffers from a lack of two elements at once. With a one-time replenishment of the missing elements, the toxicity of cardiac glycosides decreases. There is no positive effect on him. In endogenous aspartate, the function is to act as a conductor that transports magnesium and potassium ions directly to the cells of the body. Magnesium and potassium asparaginate help to improve myocardial metabolism.



When is medication prescribed?

The indication for the use of Panangin is a variety of diagnoses. Basically, Panangin tablets are recommended for use in magnesium and potassium deficiency due to the lack of these elements in the human body. If the patient eats in such a way that magnesium and potassium are not part of the food, then deficiency develops, which entails certain consequences.



Panangin is prescribed so that the body can better tolerate cardiac glycosides. The drug has found wide application in the fight against various cardiac arrhythmias, especially ventricular arrhythmias. It is used in the treatment of myocardial infarction and heart failure.

The drug Panangin, which is available in the form of tablets, should be drunk three times a day at the indicated dosage. You can not drink more than 9 tablets per day. It is advisable to drink tablets after meals so that the acidic component of gastric juice does not reduce the effectiveness of the drug. The course should last as long as the attending physician indicates, it must not be violated.

The liquid intended for intravenous administration is used by slow infusion. A single dosage should not exceed two ampoules, and the agent can be re-introduced only after 6 hours. For the infusion method, the contents of the drug ampoule are taken and mixed with 100 ml of a five percent glucose solution.





Contraindications for admission

The safety of using Panangin for the body of a pregnant woman has not been studied by the manufacturer, therefore, by default, experts do not recommend this remedy to those who are in an interesting position.

The tablet form is safer, but the manufacturers emphasize that the drug should be used with caution, especially in the first trimester. To exclude the impact on the body of the newborn, Panangin is not prescribed to women who are breastfeeding.

Like any drug, Panangin has contraindications and prescriptions for certain forms of diseases. The drug is prescribed:

• with Addison's disease;
• with cardiogenic shock;
• with hyperkalemia and hypermagnesemia;
• with anuria, oliguria;
• in acute and chronic renal failure.

Panangin can cause an allergic reaction and individual intolerance, so it is important to take the remedy under the supervision of a specialist. It is forbidden to prescribe Panangin in tablet form for hemolysis, acute acidosis, amino acid metabolism disorders, severe myasthenia gravis, and dehydration.

An overdose of Panangin is possible: if you enter an increased dose of the drug, then hyperkalemia and hypermagnesemia develop. From an overdose of the drug, a violation of the conduction of the heart may occur, it is dangerous for the body, so consultation with a specialist is necessary. Panangin reacts with other drugs, so it is important to take the drug under the supervision of your doctor. If you drink antiarrhythmic drugs for the heart, then the negative batmo- and dromotropic effects increase.



Compatibility with other drugs

If you drink Panangin and Heparin, Triamteren, Spironolactone, an ACE inhibitor, Cyclosporine at the same time, the risk of hyperkalemia will increase. If you drink Panangin along with cardiac glycoside, then the effectiveness of the latter will noticeably decrease. Intestinal peristalsis is reduced due to the simultaneous use of Panangin and an anticholinergic agent. The drug reduces the effect on the body of tetracyclines, neomycins, streptomycins and polymyxins.

Calcium agents reduce the effect of magnesium components that are part of Panangin. If you drink an agent with an anesthetic at the same time, then the inhibitory function of magnesium, which is part of the composition, is reduced. If you use the medicine together with calcitriols, then the content of magnesium in the blood plasma increases.

Among the side effects of Panangin, manifested hyperkalemia and hypermagnesemia, an increase in the number of extrasystoles, and a decrease in blood pressure stand out. Some patients experience general discomfort in the area of ​​the pancreas, sometimes there is a burning sensation in the chest. A special reaction to Panangin may be convulsions, redness of the skin, impaired respiratory function, fever. If the patient has hyperkalemia, then paresthesia and an attack of diarrhea are possible. From the introduction of injections, side effects develop much faster than when taking pills. Injections are always absorbed faster than medications delivered through the stomach.



Positive results

Panangin can be prescribed to patients who drive a car, do work that requires special attention and concentration. Caution should be taken with the drug for those who have been diagnosed with a disease associated with hyperkalemia. It is important to keep the number of ions under control. If Panangin is injected into a vein too quickly, skin hyperemia develops.

Panangin gives good results in the treatment of various diseases. First of all, you need to take into account coronary heart disease and myocardial infarction. The tool is used to combat arrhythmias of various nature. After severe infectious diseases, the human body needs potassium and magnesium to restore metabolic processes. In this case, Panangin comes to the rescue. It is prescribed to patients after blood transfusion, large blood loss, when using diuretics for a long time, for the heart. It restores the mineral balance and quickly normalizes the content of the necessary elements.



In some cases, Panangin can be used even for newborns. This allows you to close heart defects, strengthen the heart muscles of babies. The drug is used in the relief of convulsive syndromes, the causes of which are a lack of potassium and magnesium.

Means analogues

Popular analogues of Panangin are Asparkam, potassium and magnesium aspartate. These funds are similar in action, properties and a number of side effects on the human body. A group of similar drugs includes Aspangin, Pamaton. Each drug has its own characteristics, so you can not independently replace one with another.



A popular analogue of Panangin is Asparkam, which is familiar to many patients. Its release was launched many years ago and had no analogues for a long period of time. Russian Asparkam has an identical composition with Panangin, but is much cheaper. However, not all so simple. Experts say that Asparkam works worse for the heart than Panangin.

It is important to properly store Panangin. It must be kept at a temperature not exceeding 30°C. The expiration dates set by the manufacturer do not exceed 5 years, and for the liquid form - 3 years. Children should not be allowed to accidentally use the medicine. Consultation with a specialist is required.

Despite the fact that you can buy Panangin without a prescription, self-use is undesirable. This is due to the fact that a person may not realize that he has an individual intolerance or contraindications for the use of this drug.



Panangin is a drug, it does not belong to the category of vitamins or dietary supplements, so you can not drink it just like that. In order to maintain good health, you need to regularly visit a doctor and undergo an annual medical examination. Do not neglect the rules of safety and prevention of cardiovascular diseases.

The cost of the drug varies depending on the pharmacy and the region of the country, but it does not exceed 200 rubles. The price of tablets and injections is different, this is due to the form of release and production technology. The injections are stronger and the pills are less aggressive in the treatment. Therapy and the necessary drugs are selected by the attending physician. If necessary, you can replace Panangin with analogues, generics. For example, this is done when an allergy or intolerance to the components of the product occurs.