How to normalize bilirubin. Bilirubin in the blood: how to lower its level with drugs and folk remedies? Biologically active additives

Instruction

First of all, you should learn that you need to learn how to follow a strict daily routine. You should, as often as possible, walk in the fresh air. Go to bed no later than 9 pm and get up early in the morning. You need to sleep at least 8 hours. It turns out that everything is displayed if the body assumes a horizontal position.

Avoid stress and nervous fatigue. The liver cells contain an enzyme that allows you to capture bilirubin and remove it without harm. But during stress, the production of enzymes is disrupted and the accumulation of bilirubin. Help your liver deal with the problem. Don't get into conflicts. Learn to relax and meditate. Talk to your doctor about taking herbal sedatives.

Follow your diet. Remember that you are allowed to eat steamed food without spices and salt and in small quantities. But you can enrich your table with fruits and berries, as well as seaweed, which contains the necessary trace elements.

Constantly drink choleretic herbs. To start the procedures, use those that have a mild effect. These are calendula, immortelle, hill hodgepodge, corn stigmas, red mountain ash, wild rose, elecampane. Alternate these herbs when making infusions. And for their preparation, take a tablespoon of any of the listed plants and brew with a glass of boiling water. Infuse for about half an hour and strain. Drink hot 50 ml a quarter of an hour before you eat and half an hour after taking.

Keep in mind that there are several reasons for the increase in bilirubin. First of all, this is a violation of the liver and the outflow of bile from the gallbladder. An increase in bilirubin can occur with the use of certain drugs, as well as in the presence of liver cancer. Therefore, only a doctor can prescribe the appropriate one for you.

Bilirubin is coloring pigment bile. Its formation comes from the hemoglobin of destroyed red blood cells. In combination with other bile pigments, fatty acids and cholesterol, it is necessary in the digestive process, to enhance the activity of certain enzymes produced by the pancreas.

In some blood diseases (for example, hemolytic disease), there is an increased destruction of red blood cells. As a result, a large amount is released, from which the bile pigment is formed. As a result, its concentration very quickly reaches allowable rate causing jaundice.

An increase in bilirubin can also occur due to the liver, for example,. As a result, it accumulates in the blood, and, having exceeded the permissible concentration, is deposited in the skin, mucous membranes and other tissues, staining them in yellow. Moreover, jaundice appears unevenly. First of all, it becomes noticeable on a hard palate and. Further, the pigment is deposited on the face, mainly in the region of the nasolabial triangle and then on the palms and soles. With severe jaundice, bilirubin is able to stain even internal organs, sweat, tears and breast milk.

characteristic features due to hemolytic jaundice(destruction of red blood cells) are severe jaundice and dark brown color feces. With increased bilirubin caused by hepatitis (damage to liver cells), yellowness of the face and mucous membranes, urine staining in a dark color (the color of dark beer), discoloration of feces (color of white clay) and skin itching also appear.

With the normal functioning of the gallbladder, the produced is excreted into the small intestine for further digestion. However, when it stagnates in the ducts of the gallbladder, bilirubin or pigmented brown-green colors are formed, which can also cause yellowing of the skin and mucous membranes.

It is worth noting that the level of bilirubin is quite toxic for the central nervous system. And this condition is manifested by malaise, headaches, loss of strength, slowing of heart contractions (bradycardia). To avoid brain poisoning with bilirubin, the cause of its increase should be eliminated in a timely manner.

Tip 3: Elevated bilirubin in newborns: causes and treatment

After birth, the baby's body is under stress, and all its organs are trying to adapt to new conditions. The appearance of jaundice in newborns during this period indicates the destruction of fetal hemoglobin, which differs in composition from the hemoglobin of newborns.

Why is this happening

The destruction of fetal hemoglobin is accompanied by an increase in the level of bilirubin in the blood, which gives the baby's body an olive tint. This process is called physiological jaundice, appears on the 3rd-4th day of life and disappears on its own by the 3rd week. This type of jaundice does not harm the baby, but if the condition persists for a longer period, there is reason to see a doctor.

In other cases, the cause of increased bilirubin in the blood may be pathological jaundice, which is provoked by external adverse factors: severe course pregnancy, illness of the mother during childbearing. One of the main causes of pathological jaundice can be maternal diabetes. In other cases, it develops after intrauterine fetal hypoxia or asphyxia during childbirth.

These conditions can lead to damage to the baby's liver, development in the future hormonal disorders and also cause hepatic dysfunction. There can be quite a few reasons for elevated bilirubin, only a pediatrician can make a correct diagnosis after complex blood tests for bilirubin and its fractions. Various examinations of the baby are also prescribed. Only after they have been carried out, the doctor can make a diagnosis and prescribe treatment.

What is the danger of elevated bilirubin

Prolonged jaundice and high levels of bilirubin are dangerous for their toxic effects on the vital centers of the child, including his brain. With an extreme increase in the level of bilirubin, bilirubin encephalopathy may develop already on the second day after birth. Outwardly it appears constant drowsiness, decrease or absence sucking reflexes in a baby, sometimes it can significantly decrease arterial pressure, a convulsive syndrome appears. With palpation of the child's abdomen, the doctor is able to determine a significant increase in the spleen and liver.

If this condition is not treated, by six months the baby will begin to lag behind in mental and physical development, his hearing and vision may be impaired, and paralysis and paresis may develop in the future. Therefore, it is important to start therapy on time, and in the future it is necessary to be observed by a neurologist.

How is elevated bilirubin in newborns treated?

With timely treatment, you can use the simplest and most effective method- phototherapy, otherwise known as phototherapy. Under the influence of special lamps, toxic indirect bilirubin is quickly destroyed and excreted from the body with feces and urine. The baby is laid naked under the lamps of the ultraviolet spectrum, only the genitals are left closed. A special bandage is put on the eyes, the duration of exposure is prescribed by the doctor. After the procedures, peeling of the skin and the appearance of liquid frequent stools are possible.

To help the baby recover from pathological jaundice, you need to apply it to the chest more often, you need to specifically wake up the baby when it's time for feeding. Breastfeeding facilitates the removal of bilirubin from the body and promotes cleansing circulatory system and kidneys.

Bilirubin is formed in the liver during hemolysis (destruction of old red blood cells). It is a yellow pigment that gives urine its characteristic color. Normally, it is contained in the urine in very small quantities, so the reagents do not detect it. With the development of pathologies, the concentration of bilirubin increases.

How is bilirubin detected in urine

In human blood there are red bodies - erythrocytes, some of which dies off all the time and is replaced by new cells. When they break down, they release hemoglobin, which breaks down into heme molecules and globin chains. Heme is exposed to enzymes and converted into indirect bilirubin, which is a fat-soluble toxic substance. Indirect bilirubin in the liver turns into direct (water-soluble), then it is simultaneously excreted into the bile. duodenum. In case of impaired function, direct bilirubin is thrown into the blood from bile, enters the kidneys and is found in the urine. The indirect fraction cannot penetrate them, since it is not water soluble.

Bilirubin in the urine is detected by several methods: the Rosin test and the Fouche test. When conducting a Rosin test, 2-3 ml of urine is layered alcohol solution iodine (1%). If a green ring appears at the border of two fluids, this means that bilirubin is elevated in the urine. The Fouche test is performed using a solution of "Barium Chloride" (15%). It is added to urine, mixed and passed through a filter. Fouche's reagent is then dropped onto the filter. The appearance of green crystals indicates the presence of bilirubin in the urine.

Causes of increased bilirubin in the urine

The appearance of bilirubin in the urine (bilirubinuria) is a symptom of liver dysfunction. In particular, this occurs with obstructive jaundice, when the duct narrows, through which bile is excreted into the small intestine. The reason for this is usually inflammation of the pancreas. Bilirubin in the urine rises due to inflammation of the liver (hepatitis) of a bacterial, viral or toxic nature, due to cirrhosis, trauma, liver metastases. In these cases, urinalysis reveals only direct bilirubin, which has entered the bloodstream and kidneys. Its content in the blood is also above the norm. There are disorders in which there is an overabundance indirect bilirubin(for example, with hemolytic anemia), in this case, a blood test shows it, but a urinalysis does not.

A symptom of bilirubinuria is jaundice: in a patient, the sclera of the eyes, mucous membranes and skin become yellowish. This is visible to the naked eye. Liver diseases are also accompanied by heaviness in the hypochondrium, fever, nausea, bitter belching. Urine becomes dark in color, and stool becomes light. Itching of the skin appears, sometimes observed hepatic colic. If one or more symptoms appear, you should immediately consult a doctor, as bilirubinuria is a sign of a serious one. Depending on the root cause of the increase in bilirubin in the urine, appropriate treatment is prescribed.

main manifestation cholelithiasis is the presence of stones in gallbladder and ducts. The reason for their appearance is considered a violation of the metabolism of bile acids and bilirubin, cholesterol, stagnation of bile in the gallbladder and its inflammation. Factors such as a sedentary lifestyle, overeating, irregular meals significantly accelerate the process of stone formation. There are three forms of the development of the disease: physico-chemical changes in bile, lithiasis, calculous cholecystitis.

If, according to the results of the analysis, bilirubin is elevated in the blood, it is necessary to find out the reason for such a change in the composition of the blood. Elevated bilirubin is a signal for examination and enhanced treatment. To reduce the level of bilirubin, there are many drugs of different nature of origin, they can only be prescribed by a doctor after establishing the cause of the changes.

Plant Based Liver Preparations

Bilirubin has a toxic property and freely enters the cells. There is an acceptable norm for it in the body. With changes in its level, the doctor may prescribe certain means to normalize the data.

There is a group of drugs for plant-based which contains natural or semi-natural milk thistle flavonoids. They are very good antioxidants and improve protein production in damaged liver cells. At the same time, their further destruction will stop. Harmful substances do not penetrate into the liver cells. Milk thistle is able to neutralize even the alcoholic effect on the body and save it from intoxication. Excretion of harmful substances occurs along with bile. This reduces the level of bilirubin in the body.

Many drugs have been developed according to this principle. They are prescribed for elevated bilirubin. The medicine helps to reduce the intoxication of the body. But you need to drink it as directed.

What tools can be used at a high level:

Silibinin. It is prescribed to patients with liver diseases. The drug is used in the form of tablets and capsules. The dose is selected taking into account individual features. On average, in adults, this is from 70 to 140 milligrams, 2 or 3 times a day. Use this drug for intoxication with alcohol, heavy metals, hepatitis, cirrhosis of the liver. As a side effect, the patient may experience a disruption of the intestines or an allergy.
Silibor. It will be effective in hepatitis, cirrhosis of the liver. Take it with meals, three times a day. You need to be treated for a period of 30 to 60 days. Sometimes there is allergic reaction on the skin.
Silymarin-Hexal. Used in the form of capsules. Will be useful when toxic damage liver and its chronic diseases. The patient takes it up to 2 times a day, one capsule. The course of treatment will last about 90 days. Not recommended for individual use. It is also undesirable for patients under 12 years of age to take it. Possible appearance side effects in the presence of infection, disruption of the intestines.

Various pharmaceutical companies produce milk thistle-based preparations under various names.

They will be similar in their qualities:

Semi-synthetic drugs

The most popular among them:

Artichoke extract "Health". Together with artichoke extract, it contains the phenolic compound cynarin. With the help of this drug, the work of the liver and gallbladder is normalized. The body is cleansed, cholesterol levels are reduced. The amount of urine excreted increases.
Hofitol. With it, you can increase the outflow of bile, improve liver function and cleanse the body of toxins. It is used in tablet form. Specialists prescribe a remedy for liver diseases, with poor excretion of bile, kidney diseases. It can be used in treatment and prevention.
Solaren. When applied, there is a greater formation of bile and its secretion, the liver is cleansed, the work of the digestive organs improves. A liquid extract can be purchased at the pharmacy.
Holiver. Normalizes the liver and bile production. Due to the presence of medical bile in the preparation, it is able to improve and normalize metabolic processes in the body. Able to have an antiulcer effect. Assign for diseases of the liver, gallbladder, stomach ulcers.

There are also analogues of these drugs that a doctor can prescribe. The process of reducing bilirubin in the blood should occur under the supervision of a doctor so that it is possible to adjust the treatment. You can not choose and take medicines on your own. They should be drunk strictly according to the recommended dosage.

Means of animal origin and based on phospholipids

Preparations of this group are able to restore liver tissue and cleanse the body.

They are used to reduce bilirubin:

Sirepar. Restores the tissue structure of the liver. It is applied in the form of injections. It is used for cirrhosis, hepatitis, liver intoxication. Be sure to do tolerance tests.
Erbisol Ultrapharm. It helps to improve immunity and restore damaged cells, remove the virus from cells. Used for viral hepatitis intravenously and intramuscularly.
Hepatosan. It is based on animal liver cells. It helps in the treatment of cirrhosis, improves protein production. Helps repair damaged cells.

Phospholip. When using this drug, it dissolves in water. Full effect occurs 6 or 8 hours after ingestion. It restores metabolic processes, immunity and the production of lymphocytes that could be damaged by infection or harmful substances. Release it in capsules. It is prescribed for liver diseases, intoxication of the body.
Essentiale. In pharmacology, it is used in capsules. It is able to get into the liver cells and restore them. It is used for cirrhosis, liver intoxication with drugs, toxicosis, gallbladder diseases. He is able to fix lipid metabolism with cardiac ischemia.

Synthetic-based drugs can also be added to these groups:

They have similar properties. Frequent advice: Drink them with plenty of water.

Regarding side effects and contraindications, it is necessary to study in detail each specific case. But for all drugs there are several unifying points. It is necessary to conduct a tolerance test, after taking the patient, there may be a violation of the intestines. With the help of such drugs, you can reduce the level of bilirubin in the blood, but you need to treat the cause of its increase.

How to lower bilirubin in the blood with folk remedies

Many of us have come across in the results of analyzes with such a concept as bilirubin. Everyone knows that increased amount bilirubin in the blood can be dangerous. But what is this enzyme? What is bilirubin and what is its function?

Bilirubin is one of the main components of bile, the result of the breakdown of proteins, which is formed in the liver. Normally, bilirubin is produced in the amount of 300 mg per day in an adult. Bilirubin, along with bile, is excreted through the intestines, which is why feces healthy person has a brown tint. If suddenly the feces become colorless, this may indicate a violation of the liver.

When there is too much bilirubin, bile penetrates the tissues, staining them with a yellow pigment. First, the sclera becomes yellow, and then the skin. By itself, an increase in bilirubin is not a disease, but only a symptom of another failure in the body. However, bilirubin, getting into body tissues, has toxic effect. That is why, in addition to treating the underlying disease, it is important to reduce the level of yellow pigment in the blood.

Causes of increased bilirubin

Before you start fighting high bilirubin, you need to understand what could cause such a state of the body. Eliminating the cause will help to quickly cope with the symptom.

One of the main reasons for the increase in bilirubin is the deterioration of the liver. This is most often associated with hepatitis A, B, or C. Also, the liver may begin to work poorly due to infectious diseases, cirrhosis, hepatosis.
With cholelithiasis and inflammation of the pancreas, the outflow of bile into the intestine is disturbed. That is why bile, finding no way out, is absorbed into the tissues.
Bilirubin often increases with severe intestinal poisoning, with salmonellosis.
Sometimes yellow pigment can be the result of chemical poisoning, taking a large number medicines, such as antibiotics.
Sometimes elevated bilirubin observed in pregnant women in the third trimester of pregnancy in violation of the outflow of bile.
"Newborn jaundice" - this is the name for the increased content of bilirubin in the blood of young children immediately after birth. This is due to the imperfection of the functioning gastrointestinal tract. Usually such jaundice lasts for several weeks and does not require special treatment. It lasts longer in premature, low birth weight babies. However, if the yellowness of the integument does not go away for a very long time, this requires special therapy, since prolonged bilirubin poisoning can lead to changes in the subcortex of the brain.

First of all, you need to deal with the very cause of the increase in bilirubin, a doctor will help you with this. And only then the question arises of how to quickly remove intoxication and remove this bilirubin from the body.

Diet with elevated bilirubin

The liver is known to be a self-healing organ. Most liver diseases are not treated with drugs and medicines, but strict diet. Diet implies the maximum reduction in the load on this important organ. In order not to overload the liver, you need to eat fractionally, very modest portions. Better 5-6 light meals than 3 heavy meals. With increased bilirubin, you need to adhere to the following rules in nutrition.

Excluded all fatty, fried, smoked, spicy, strictly prohibited any alcoholic drinks, marinades, canned food, mayonnaise, ketchup, soda.
It is better to eat lean beef, poultry, fish. It is better to refuse lamb and pork. The meat is best boiled or steamed.
All meals must be lean. No need to load the liver with fatty meat broths, it is better to give preference to vegetable and milk soups.
Drink more green tea, various herbal teas.
You can use any dairy products, except for the fattest ones - sour cream, cream.
Egg whites, fruits, vegetables, cereals - no restrictions.
Can't eat fresh bread, muffin. It is better to consume crackers, yesterday's dried bread.
Salt and coffee increase the amount of bilirubin produced, so their consumption should be reduced to a minimum.
Drink more water to remove the hated pigment from the blood - at least three liters per day.

In addition, it is necessary to minimize physical activity It is also a burden on the liver. Try to avoid stress and nervous strain. Rest more, give preference to proper nutrition always, and not only in the midst of certain diseases.

Drug-induced decrease in bilirubin

But is it possible to reduce the level of yellow pigment with medication? Of course you can. First of all, the underlying disease is treated, that is, the cause of the increase in bilirubin is eliminated. In addition, in case of violation of the outflow of bile, the patient is prescribed choleretic drugs, such as Allochol, Hofitol, Karsil, Cholenzim.

To cleanse bile from the blood, gastrointestinal tract, liver and lymph, simple sorbents are often prescribed, such as Activated carbon or Polysorb. If liver damage is caused by herpes diseases, are given antiviral agents such as Acyclovir. Besides, Special attention is given to immunomodulatory and vitamin complexes that help maintain immunity at the proper level.

If the amount of bilirubin is very high, the doctor prescribes intravenous infusions of glucose. This helps to remove the intoxication of the body and wash out some of the yellow pigment. The patient is also required to be prescribed hepaprotectors - a group of drugs that help restore liver function. Among them are Ursosan, Essentiale, Hepatrin.

In addition to basic therapy, newborns are kept under an ultraviolet lamp to reduce the level of yellow pigment.

Folk remedies to reduce bilirubin

In addition, there are many recipes from herbs, vegetables and fruits that will help you speed up the process of removing bilirubin from the body.

Chamomile, St. John's wort, motherwort. Prepare a concentrated decoction of these herbs. Mix one tablespoon of each herb and pour a liter of boiling water over the collection. Let it brew for an hour, and then strain and drink the decoction throughout the day.
Beet juice. Help improve liver function beetroot juice. Dilute the juice in half with water and drink one-third of a glass before each meal.
Birch leaves. A decoction of birch leaves will help enhance the diuretic effect. Gather the leaves and wash and dry them thoroughly. A liter jar will need a handful of such leaves. Pour birch leaves boiling water and wrap tightly. Let it brew, then drink every 4 hours a glass of the prepared broth.

Folk recipes for the treatment of the liver and lowering the level of bilirubin are good because they do not give such a toxic effect as many drugs. In addition, they are easy to prepare and absolutely accessible to everyone.

Elevated bilirubin in the blood - serious symptom which cannot be ignored. If yellowness is detected on the skin and sclera, urgent hospitalization and finding out the reason similar condition organism. Remember - bilirubin is very toxic, and you need to remove it from the tissues of the body as soon as possible!

Treatment for elevated bilirubin

The amount of bilirubin: norm and deviation

Due to the peculiarities of passing through all stages of the transformation of a substance, indirect and direct bilirubin are distinguished. Blood

The formation of direct acid-bound bilirubin occurs in the liver. It is not dangerous and is ready to be excreted from the body. Quantitative content - no more than 4.5 µmol/l.
Indirect bilirubin increased in cases where its content exceeds 16.4 µmol/L. This type of bilirubin is toxic, it is he who does not bind to albumin protein and can penetrate the liver.
Content total bilirubin should remain within the range of up to 20.5 µmol/l.

Reasons for the development of disorders

The reasons for the increase in bilirubin in the blood are associated with the influence of the following factors:

The rapid acceleration of the destruction of red blood cells - a similar deviation is often observed in hemolytic anemia.
Violations of the conversion of bilirubin in the liver.
Violations of the excretion of bile from the body.
Reception of certain groups of drugs.
Infection with worms.

Hyperbilirubinemia can cause staining skin and fabrics:

The sclera of the eyes acquire a yellowish tint.
There is staining of the oral mucosa.
AT running case the patient's skin (feet, palms) also acquire a yellow color.

Manifestations of hyperbilirubinemia

Elevated bilirubin in the blood in the case of hemolytic anemia is manifested as follows:

The patient is concerned about discomfort in the left hypochondrium (enlarged spleen).
The body temperature rises.
Urine turns dark (black or dark brown). This may indicate the destruction of red blood cells.
The patient complains of feeling tired, headache development of tachycardia. This is due to a violation of the supply of oxygen to the body.

Symptoms of hyperbilirubinemia in diseases of the liver and cholelithiasis

Liver enlargement and development pain syndrome in the region of the right hypochondrium.
Development of nausea after eating, belching bitterness.
Increased fatigue and weakness.
The patient's stool may become discolored, and the urine may take on a dark color ( strong tea or dark beer).
In the case of the development of viral hepatitis, an increase in body temperature is observed.

With gallstone disease and a violation of the outflow of bile, the following symptoms occur:

Severe itching of the skin.

Complaints of belching bitterness, nausea, lack of appetite.

The development of flatulence and stool disorders (diarrhea and constipation).

Complete discoloration of feces.

Pronounced staining of urine in a dark color.

Therapy of the disease

Treatment of elevated bilirubin levels is carried out in several stages. First of all, infusion treatment with the use of glucose preparations and detoxification agents is required. This allows you to cleanse the body of the level of breakdown of red blood cells. Such therapy is carried out in the event of a serious condition.

Proper nutrition

Diet plays an important role in the treatment of elevated bilirubin. Patients with hyperbilirubinemia are advised to reduce the intake of salt, white bread, butter, foods rich in cholesterol and products with high content baking powder and soda (cake, pastry, muffin). You should refrain from eating mushrooms, sorrel, garlic, radishes and green onions, spicy and sour dishes and seasonings, chocolate, alcohol and ice cream, smoked, industrial sweets and canned food.

We answer the question of how and how to reduce bilirubin in the blood

The physiological role of bilirubin in the human body is quite large, as evidenced by numerous Scientific research, which show that bilirubin is necessary for the body to utilize hemoglobin. This pigment is formed due to the breakdown of hemoglobin. Its traces are found in blood serum and bile.

Substance deviations from the norm can lead to serious illnesses– hemolytic anemia, cancer, hepatitis and others.

Types of bilirubin

Total bilirubin in blood serum in adults has the following types:

It all depends on the results of the laboratory reaction with a specific reagent. The direct fraction is a substance rendered harmless by the liver. The second variety is toxic high bilirubin, which managed to bind in the liver.

Simple and clear about bilirubin

Norms

To determine what level of bilirubin, it is required to conduct biochemical research. For analysis you need deoxygenated blood. The selection of material for research is necessarily taken on an empty stomach. The last meal before visiting the laboratory should be no earlier than 8 hours.

for the general pigment - 5.1-17 mmol / l;
for indirect - 3.4-12 mmol / l;
for direct - 1.7-5.1 mmol / l.

Main reasons

The following reasons can provoke a condition in which the rate of total bilirubin is increased:

accelerated destruction or increased presence of red blood cells;
dysfunction of the outflow of bile;
malfunctions in the activity of the liver.

In addition, long-term use of drugs, such as:

A similar problem may be hiding in a hereditary deficiency of the liver enzyme that is involved in the conversion of total bilirubin.

Gilbert's syndrome can also lead to an increase.

Symptoms

The main symptoms when the overall pigment index is high are:

decreased appetite;
intermittent pain in the right hypochondrium;
bloating;
skin itching due to irritation of the nerve roots by bilirubin;
darkish shade of urine;
hepatic colic;
fatigue;
migraine;
cardiopalmus.

Treatment

When a person often experiences symptoms that are not characteristic of his body, it is urgent to contact a specialist who will decide how to lower bilirubin in the blood of a particular patient. To quickly deal with the problem, you need an integrated approach. The patient during treatment may need:

medications;
diet;
decoctions from medicinal plants.

Medications

When the causes of the increased value are a violation of the outflow of bile, in this case, the patient is prescribed choleretic drugs. If the reason lies in hereditary predisposition, he will have to carry out symptomatic treatment, which involves taking sorbents, choleretic agents, vitamins, medicines that reduce bilirubin in the blood.

With the inflammatory nature of the functioning of the liver, infection of the body or immune disorders the following medications may be prescribed:

antibacterial;
antiviral;
immunomodulating;
enzymatic;
hepatoprotectors.

The latter are prescribed in the first place, since they help to improve the condition of the liver and normalize its activity. To reduce bilirubin, when its causes are caused by Gilbert's syndrome, it is appropriate to take Phenobarbital and Zixorin at 0.05–0.2 g per day. The course is designed for a period of 14 days to a month. Patients are also recommended enzyme preparations facilitating the general condition.

These include:

Take these funds 1-2 tablets three times a day 20 minutes before meals. For the general maintenance of liver activity, drugs based on natural ingredients can be involved:

To enhance the effect of bilirubin excretion, it is necessary to additionally use absorbent preparations, which are distinguished by a good ability to bind bilirubin and remove it from the body. These include:

Enterosgel;
Absorbent;
activated carbon and others.

A lot of useful information about bilirubin, a test for it + very useful tips

Diet

When analyzing the question of how to reduce bilirubin in the blood, it should be understood that medications taken at home alone are not enough. Additionally, a special diet is required.

Healthy food is good for the liver. She lets you take it off extra load and at the same time drug treatment works well on the causes of liver failure.

Nutrition during home treatment is aimed at limiting or eliminating certain foods from the patient's diet that can cause system failure. These are:

coffee and salt;
citrus;
heavy food, fried, spicy, salty and smoked dishes;
alcohol;
mushrooms;
radish.

It is necessary to abandon all products that contain baking powder, acids, preservatives.

It is useful for patients to eat:

egg white;
dairy;
fruits (only sweet);
lean meat;
vegetable and milk soups;
rice, oatmeal, and buckwheat porridge;
fruit drinks;
mineral water;
herbal teas.

The latter remedy is especially valuable because it quickly removes excess bilirubin from the blood of a newborn.

Alternative treatment

Treatment performed at home folk remedies when such a problem is present, it is recommended to perform with a tincture of birch leaves. For the recipe you need 1 tbsp. l. dry crushed product and a glass of boiling water. Decoction insist half an hour and take before bedtime. This drug has sedative properties and helps to quickly remove from the liver toxic substances including indirect bilirubin.

A decoction based on St. John's wort, chamomile and motherwort is one of the most effective drugs in the treatment of folk remedies. The result of such tea can be seen within 10 days after ingestion. To prepare a healing drink, you need dried grass of the above plants in the amount of 1 tbsp. l. to a glass of boiling water. The infusion should be left for 30 minutes so that it gains strength, and then consumed twice a day 20 minutes before meals.

Freshly squeezed beet juice will help reduce the level of bilirubin only with folk remedies. This drink has a choleretic effect. It is recommended to drink beetroot juice 1/3 cup before meals.

Among those that are called folk remedies, corn stigmas have excellent properties. For the recipe, you need 2 dl. raw materials and a glass of boiling water. The broth must be infused for 30 minutes, then strain and take twice a day for half a cup.

Good results are shown by the use of motherwort in the treatment of folk remedies. For a glass of boiling water you need to take 1 tbsp. l. dry grass. Leave the mixture for half an hour to infuse. You need to drink liquid on an empty stomach, 60 ml.

Effects

Blood supersaturated with bilirubin negative impact on the activity of the brain, as it is attacked by toxic metabolic products. In addition, liver cells suffer, causing even more disruption in the activity of the organ. The entire load during this period falls on the kidneys, which are no longer able to fully cope with the task. As a result, they become vulnerable, undesirable processes begin to occur in them.

Decreased bilirubin level

Low bilirubin may occur if acute leukemia, kidney failure, tuberculosis intoxication. In the case of such diseases, its concentration decreases, as the number of red blood cells decreases.

Important: Low bilirubin is diagnosed very rarely.

Features of the treatment of children and pregnant women

The newborn often has elevated bilirubin. This phenomenon occurs due to the destruction of fruit hemoglobin. In a newborn, it is slightly different in structure from the one that is formed before childbirth. Since hemoglobin is actively destroyed in the fetus, the level of bilirubin increases accordingly in the newborn.

In pregnant women, bilirubin rises due to the growth of the fetus and its location. Since the child presses on the liver, the outflow of bile from it is difficult, so its accumulation occurs.

Important: During pregnancy, drugs that reduce bilirubin should be abandoned, and the cleaning procedure should be performed with herbs that do not affect the fetus, as well as following a diet.

Prevention

eat properly;
get rid of bad habits;
observe hygiene.

Clinic and cost

Get exact result bilirubin level can be obtained by visiting one of the independent laboratories of INVITRO LLC. The cost of diagnostics is 265 rubles, plus you will have to pay another 199 rubles for the procedure for taking blood from a vein for analysis.

How and how to reduce bilirubin in the blood

An increased concentration of this pigment begins to poison the human body. Bilirubin is a pigment that is formed in the body as a result of natural processes.

How to lower bilirubin in the blood - popular folk remedies

How to lower bilirubin in the blood using folk remedies?

Here are some options:

Infusion of herbs, in particular from St. John's wort, chamomile and mint. You can use the pharmacy option, that is, just buy a special herbal tea at the pharmacy.

It is worth noting that the result will appear only after two weeks of constant use.

But one should not think that if it exceeds the dosage, it will contribute more quick effect. But you can make it yourself: scald about 250 g of these herbs with boiling water and let them brew for at least half an hour. You need to drink a decoction twice a day and prepare a new decoction each time.

Beet juice. This diuretic option will help you cleanse the body, as well as reduce the level of the ill-fated pigment in the croque. To do this, you need to squeeze the juice with the help of a juicer and drink a third of a glass before eating.

Birch leaf tinctures. You need to take a spoonful of dry crushed leaf, brew it and insist in a cup of boiling water. It is advisable to drink such a decoction before going to bed.

Motherwort tinctures. You can use this method: pour 20 grams of dry grass with boiling water. For some time, the tincture should stand. And then on an empty stomach you can drink 60 ml.

Corn silk. The ingredients are simple: two small spoons of such stigmas should be poured with boiling water and let it brew. For one glass two spoons, and then you should drink half a glass before going to bed.

The advantage of such folk methods of treatment is their safety for health and low cost. It is clear that many medicines operate on the principle of "here they treat, but there they cripple."

But do not engage in self-deception and think that only decoctions and tinctures can get rid of such a problem.

Elevated bilirubin in the blood may indicate serious problems so it's not worth the risk. It is necessary to consult a doctor who will prescribe an effective treatment.

What is bilirubin

This is a pigment that is formed in the body as a result of the breakdown of red blood cells, as well as processes for the conversion of hemoglobin.

It is yellow-brown in color and is found in bile. Bilirubin appears in the body as a result of normal processes and it exists in two forms.

The first form is insoluble bilirubin, which enters the blood with the liver and dissolves there, and the second is a soluble or direct form that dissolves in water and is obtained as a result of the transformation of the first form.

Bilirubin appears in the blood as a product of the processing of red blood cells, then it enters the liver and turns into a direct form. After that, it must be excreted from the body along with bile. This is a normal process, but if this does not happen, problems may begin.

300 mg of this pigment is formed per day, which means that an indicator from 3.4 to 17 mmol per liter is considered normal. An indicator of 20.5 mmol and above is considered an alarming indicator.

Causes of increased pigment levels

The flow of bile may be impaired. This can occur as a result of the formation of kidney stones, as well as inflammation of the pancreas, which may be accompanied by swelling and other symptoms.
Impaired synthesis of glucuronides, since there are no necessary enzymes. This problem is typical for cirrhosis, hepatitis and hepatosis.
The cause may be hemolytic anemia and other factors that contribute to the abnormally rapid breakdown of red blood cells.
If you use any antibiotics and other medicines during this period, this may affect the level of bilirubin.

The whole truth about bilirubin on video

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Therapy and drug treatment

With an increased level of bilirubin, the following treatment is prescribed:

Cholagogue drugs - if the cause is problems with the outflow of bile. Such medicines include Karsil, Allohol and others.
Hepatoprotectors are a group of drugs that will help improve the functioning of the liver.
Antioxidants and sorbents - if the cause feeling unwell is intoxication and the actual increase in the level of this protein.

Against the background of these problems, flatulence may occur and then a simple drug will help: activated charcoal.

When we are talking about serious problems with the liver, for example, with various forms hepatitis, that is, anti- inflammatory processes, then it is necessary to take antibacterial, as well as anti-inflammatory, immunomodulatory drugs.

Proper nutrition and special diets

How to lower blood bilirubin in adults with a diet? There is certain products that should be eliminated from your diet:

Acute;
Smoked and all marinated;
Fried;
Any alcoholic drinks;
Cold and carbonated drinks.

There are a few more tips: you should give up foods that your body does not digest well. It is best to cook all dishes for a couple or boil.

And although you need to drink more fluid to reduce bilirubin to stimulate the gallbladder, you should not drink cold water and various sodas.

You should also limit the consumption of tea and coffee. It is best to drink various fruit drinks, compotes and decoctions. Doctors also advise eating not black bread, but, for example, gray bread.

The following foods will help lower the amount of bilirubin in the blood:

All dairy;
Milk soups, as well as vegetable soups, that is, all light first courses;
Lean meat;
Sweet fruits;
Special herbal teas and decoctions.

If you stick to these simple rules, then you will not only get low bilirubin in the blood, but you will also be able to improve your well-being. And yet it is worth understanding that proper nutrition and diets are more preventive measures rather than the main treatment.

Excessive physical activity;
Stress, depression and nervous breakdowns;
Eat right always, not just when such problems arise.

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Consequences and complications of elevated bilirubin in the blood

Bilirubin is the main pigment of bile and a permanent component of the blood, formed during the breakdown of proteins. It is this substance that gives urine a yellow color, and feces - dark, and has toxic properties that can poison tissues. High level bilirubin in the body is a serious threat to human life, which is why when this fact is discovered, a doctor should be consulted immediately.

Distinguish indicators of direct and indirect bilirubin. The liver has already neutralized the first type and prepared it for removal from the body (its normal value- up to 5.1 µmol/l), and the second type is toxic (no more than 16.1 µmol/l). normal level overall indicator can reach up to 17.5-20.5 µmol/l.

With jaundice, for example, bilirubin can increase to 34 µmol / l. In this case, the liver is affected, and the tissues and mucous membranes have a yellow tint: the sclera turn yellow first, the next is the oral mucosa, then signs of jaundice appear on the skin of the face, palms, soles and throughout the human body. At night, there is an increase in skin itching.

It has been established that three main factors increase bilirubin in the blood:

acceleration or increase in the process of destruction of red blood cells;
impaired outflow of bile;
dysfunction of metabolism and removal of pigment from the body.

Direct bilirubin also increases due to the presence of a number of diseases:

acute viral, chronic, bacterial hepatitis;
hemolytic anemia, a common feature of which is increased destruction of red blood cells: toxic (in case of poisoning poisonous mushrooms etc.); medicinal (due to taking drugs against tuberculosis, tumors, etc.);
jaundice of pregnant women;
liver tumors;
hereditary jaundice (with Rotor and Dubin-Johnson syndromes);
biliary cirrhosis.

Indirect bilirubin has the ability to increase the rate in the following diseases:

hemolytic anemia of congenital and acquired character;
infectious diseases, which include typhoid fever, sepsis, malaria;
hemolytic anemia of drug etiology (provoked, for example, by antibiotics and other drugs);
hemolytic anemia of a toxic nature.

Pathologies associated with jaundice of the liver are of great variety, but the most common and serious are hepatitis and cirrhosis. Bilirubin is no longer neutralized and removed from the body by the liver, the process of detoxification and the formation of various proteins and blood coagulation factors is not carried out by it.

Cirrhosis is the final stage of hepatitis, which is marked by the following symptoms:

significantly enlarged spleen and liver;
fluid formation in abdominal cavity(ascites);
varicose veins of the rectum, esophagus, anterior abdominal wall;
liver failure;
brain death;
decreased blood clotting and other consequences leading to death.

So, an increased level of bilirubin in the blood - a toxic and dangerous compound - leads to the following complications:

body intoxication.
Negative effect on brain activity.
Violations of the functions of all organs and systems without exception.

First of all, connective tissues and brain cells suffer from the destructive effect of toxins. Especially big risk exposed to newborn children whose body is in initial period formation, and for him every cell has a significant value. Enhanced Level bilirubin in the blood causes jaundice in infants, resulting in Negative influence on brain and liver cells, causing irreversible consequences in the absence of effective therapeutic assistance.

Bilirubin is a pigment that is one of the principal components of bile in the body of both humans and animals. Generally speaking, it is synthesized due to the breakdown of proteins that contain heme - that is, in hemoglobin, myoglobin and cytochrome. As for localization, the liver, spleen, bone marrow and lymph nodes are responsible for its production, from where bilirubin enters the bile. It is also present in small amounts in the blood, representing two fractions - free and bound. Some diseases and other negative factors can increase or decrease the level of bilirubin, and in order to find out the reasons for this, the doctor prescribes a change to the patient biochemical analysis blood.

The process of synthesis of bilirubin in the body

You should start with the fact that every day in human blood natural causes about one percent of erythrocytes, that is, red cells, is destroyed (the liver, spleen and bone marrow are responsible for their decay). As a result of the destruction of red blood cells, hemoglobin is formed, which in turn then forms verdoglobin. This component subsequently loses globin and iron, turning into biliverdin, and then it goes through the process of recovery to bilirubin. In fact, the latter is an orange pigment that begins its existence in a free form. Then, after a series of transformations, it is divided into two parts: the first enters the intestines with bile, staining the feces in a normal color, and the second, together with the blood, ends up in the kidneys, after which it is excreted in the urine (again, giving it a characteristic yellow color).

Today, doctors divide bilirubin into indirect (toxic, insoluble) and direct (harmless, soluble): their sum is referred to as “total bilirubin”, whose level allows us to identify probable causes diseases by conducting a biochemical blood test. In some situations, it develops reduced level, with others, it can be increased, which leads to such a notorious disease as jaundice - in this case, you need to quickly understand how to lower bilirubin in the blood.

Causes of increased bilirubin

The reasons that led to a significant increase in bilirubin may have a different etiology, but all of them, without exception, end in jaundice, which is divided into several varieties:

suprahepatic (hemolytic);
hepatocellular (parenchymal);
subhepatic (mechanical).

characterized by pathologically excessive breakdown of erythrocytes, as a result of which the liver cannot cope with the increased need to transform indirect bilirubin into direct bilirubin. As a result, an excessive amount of this component accumulates in the blood, after which a similar situation occurs both in the intestines with stercobilin and in the urine with urobilin. The causes that lead to suprahepatic jaundice are divided by doctors into hereditary and acquired. The former include the syndromes of Dubin-Jones, Rotor, Gilbert, Crigler-Nayar and others, the latter - different kind anemia, toxic or infectious diseases, as well as taking antibiotics, anti-inflammatory or hormonal drugs.

Hepatocellular jaundice is also called true, and the causes of its development are various lesions of the liver parenchyma. The consequence of this is a decrease in the functioning of hepatocytes responsible for the transformation of indirect bilirubin into direct. In turn, this leads to the fact that its content in the blood increases significantly, as well as the amount of aldolase, aminotransferases and other components. The symptoms are as follows:

staining of the skin and mucous membranes in a reddish color (up to green with a long course of the disease);
mild itching of the skin;
dark color of urine;
discolored feces;
a significant decrease in the ratio of produced stercobilins and urobilins (up to 1:1 at a rate of 10:1 to 20:1).

As for the diseases that most often cause hepatic jaundice, they include viral or chronic hepatitis, leptospirosis, sepsis, and some toxic poisons.

Finally, during stagnation bile ducts, which is caused by stones, tumors or edema, obstructive jaundice develops. Due to the ongoing processes, the bile vessels increase markedly, which increases the level of permeability of their walls - this means that more bilirubin will be able to get into bloodstream and cause jaundice. Its classification includes such types as subhepatic, obstructive, congestive and compression. To diagnose them, doctors use various methods invasive and non-invasive kind: the former include transhepatic or endoscopic cholangiography, to the second - ultrasonic, magnetic resonance and computer diagnostics.

The reasons that led to the occurrence obstructive jaundice, wear the most different character but the main ones are:

stones in the bile ducts or their cicatricial narrowing;
cyst in the pancreas;
chronic or acute pancreatitis accompanied by swelling of the pancreas;
portal biliopathy;
stomach cancer;
malignant tumor formations in the liver, bile ducts, head of the pancreas;
Mirizi syndrome.

It remains to be added that another reason for the increase in bilirubin may be a lack of cyanocobalamin, vitamin B12, in the body.

Symptoms of jaundice

All these cases are quite easy to distinguish from true jaundice due to the fact that the color of the eye sclera remains normal.

But the clinical manifestations of jaundice of any type are complex, and the set of these signs directly depends on the type of this disease, which is why the primary task of any doctor is to determine the type and causes of the disease. Common feature only one: consistent yellow staining of the skin (first the face, then the palms, feet and the rest of the body), the sclera of the eyes and mucous membranes, and the shade can range from pale to orange or even reddish. It is worth considering the fact that the color of the skin with jaundice directly depends on the natural color of the patient's skin. In addition, in overweight people, yellowing is less pronounced than in thin people.

Nevertheless, it is possible to describe a general set of symptoms that in a given situation may indicate the development of jaundice due to an increase in the level of bilirubin in the blood. This list looks like this:

dark color of urine;
skin itching;
bleeding;
bone pain;
chills;
hepatic colic;
xanthoma and xanthelasma;
spider veins, ascites;
cachexia (extreme exhaustion);
nausea or vomiting.

Decreased bilirubin level

At the first detection of signs of yellowing of the skin or eye sclera, a person should immediately consult a doctor, since only he knows how to lower bilirubin in the blood. Self-medication or, even more so, the use of folk remedies can lead to disastrous consequences. In some cases, the patient will need hospitalization, where as a treatment method will be used drug therapy, herbal medicine, surgery or endoscopy. As for drugs, the main ones in treatment are Sirepar, Silibor, Silibinin and others, which are combined with drugs like Dibazol and No-shpa. Along with this, doctors sometimes resort to the use of dietary supplements.

In addition to all of the above, the patient is prescribed strict observance diet, drinking regimen and restriction of physical activity.

Important!

HOW TO SIGNIFICANTLY REDUCE THE RISK OF CANCER?

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1. Can cancer be prevented?
The occurrence of a disease such as cancer depends on many factors. No one can be completely safe. But significantly reduce the chances of occurrence malignant tumor everyone can.

2. How does smoking affect the development of cancer?
Absolutely, categorically ban yourself from smoking. This truth is already tired of everyone. But quitting smoking reduces the risk of developing all types of cancer. Smoking is associated with 30% of deaths from oncological diseases. In Russia, lung tumors kill more people than tumors of all other organs.
Eliminate tobacco from your life - the best prevention. Even if you smoke not a pack a day, but only half, the risk of lung cancer is already reduced by 27%, as the American Medical Association found.

3. Does excess weight affect the development of cancer?
Keep your eyes on the scales! Extra pounds will affect not only the waist. The American Institute for Cancer Research has found that obesity contributes to the development of tumors in the esophagus, kidneys, and gallbladder. The fact is that adipose tissue serves not only to store energy reserves, it also has a secretory function: fat produces proteins that affect the development of a chronic inflammatory process in the body. And oncological diseases just appear against the background of inflammation. In Russia, 26% of all cancer cases are associated with obesity.

4. Does exercise help reduce the risk of cancer?
Set aside at least half an hour a week for exercise. Sport is on the same level as proper nutrition when it comes to cancer prevention. In the US, a third of all deaths are attributed to the fact that patients did not follow any diet and did not pay attention to physical education. The American Cancer Society recommends exercising 150 minutes a week at a moderate pace or half as much but more vigorously. However, a study published in the journal Nutrition and Cancer in 2010 proves that even 30 minutes is enough to reduce the risk of breast cancer (which affects one in eight women in the world) by 35%.

5.How does alcohol affect cancer cells?
Less alcohol! Alcohol is blamed for causing tumors in the mouth, larynx, liver, rectum, and mammary glands. Ethyl alcohol breaks down in the body to acetaldehyde, which then, under the action of enzymes, passes into acetic acid. Acetaldehyde is the strongest carcinogen. Alcohol is especially harmful to women, as it stimulates the production of estrogen - hormones that affect the growth of breast tissue. Excess estrogen leads to the formation of breast tumors, which means that every extra sip of alcohol increases the risk of getting sick.

6. Which cabbage helps fight cancer?
Love broccoli. Vegetables are not only part of a healthy diet, they also help fight cancer. This is why recommendations for healthy eating contain the rule: half daily ration should be fruits and vegetables. Especially useful are cruciferous vegetables, which contain glucosinolates - substances that, when processed, acquire anti-cancer properties. These vegetables include cabbage: ordinary white cabbage, Brussels sprouts and broccoli.

7. Which organ cancer is affected by red meat?
The more vegetables you eat, the less red meat you put on your plate. Studies have confirmed that people who eat more than 500 grams of red meat per week have a higher risk of developing colon cancer.

8. Which of the proposed remedies protect against skin cancer?
Stock up on sunscreen! Women aged 18-36 are particularly susceptible to melanoma, the deadliest form of skin cancer. In Russia, in just 10 years, the incidence of melanoma has increased by 26%, world statistics show an even greater increase. Both artificial tanning equipment and the sun's rays are blamed for this. The danger can be minimized with a simple tube sunscreen. A study published in the Journal of Clinical Oncology in 2010 confirmed that people who regularly apply a special cream get melanoma half as often as those who neglect such cosmetics.
The cream should be chosen with a protection factor SPF 15, apply it even in winter and even in cloudy weather (the procedure should turn into the same habit as brushing your teeth), and also do not expose yourself to the sun's rays from 10 to 16 hours.

9. Do you think stress affects the development of cancer?
By itself, stress does not cause cancer, but it weakens the entire body and creates conditions for the development of this disease. Research has shown that constant worry alters the activity of the immune cells responsible for turning on the fight-and-flight mechanism. As a result, a large amount of cortisol, monocytes and neutrophils, which are responsible for inflammatory processes, constantly circulate in the blood. And as already mentioned, chronic inflammatory processes can lead to the formation of cancer cells.

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Many of us have come across in the results of analyzes with such a concept as bilirubin. Everyone knows that an increased amount of bilirubin in the blood can be dangerous. But what is this enzyme? What is bilirubin and what is its function?

Bilirubin is one of the main components of bile, the result of the breakdown of proteins, which is formed in the liver. Normally, bilirubin is produced in the amount of 300 mg per day in an adult. Bilirubin, along with bile, is excreted through the intestines, which is why the feces of a healthy person have a brown tint. If suddenly the feces become colorless, this may indicate a violation of the liver.

When there is too much bilirubin, bile penetrates the tissues, staining them with a yellow pigment. First, the sclera becomes yellow, and then the skin. By itself, an increase in bilirubin is not a disease, but only a symptom of another failure in the body. However, bilirubin, getting into the tissues of the body, has a toxic effect. That is why, in addition to treating the underlying disease, it is important to reduce the level of yellow pigment in the blood.

Causes of increased bilirubin

Before you start fighting high bilirubin, you need to understand what could cause such a state of the body. Eliminating the cause will help to quickly cope with the symptom.

One of the main reasons for the increase in bilirubin is the deterioration of the liver. Most often this is associated with hepatitis A, B or C. Also, the liver may begin to work poorly due to infectious diseases, cirrhosis, hepatosis.
With cholelithiasis and inflammation of the pancreas, the outflow of bile into the intestine is disturbed. That is why bile, finding no way out, is absorbed into the tissues.
Bilirubin often increases with severe intestinal poisoning, with salmonellosis.
Sometimes yellow pigment can be the result of chemical poisoning, taking a large number of drugs - for example, antibiotics.
Sometimes elevated bilirubin is observed in pregnant women in the third trimester of pregnancy in violation of the outflow of bile.
"Newborn jaundice" - this is the name for the increased content of bilirubin in the blood of young children immediately after birth. This is due to the imperfection of the functioning of the gastrointestinal tract. Usually such jaundice lasts for several weeks and does not require special treatment. It lasts longer in premature, low birth weight babies. However, if the yellowness of the integument does not go away for a very long time, this requires special therapy, since prolonged bilirubin poisoning can lead to changes in the subcortex of the brain.

The liver is known to be a self-healing organ. Most liver diseases are not treated with drugs and medicines, but with a strict diet. Diet implies the maximum reduction in the load on this important organ. In order not to overload the liver, you need to eat fractionally, very modest portions. Better 5-6 light meals than 3 heavy meals. With increased bilirubin, you need to adhere to the following rules in nutrition.

Excluded all fatty, fried, smoked, spicy, strictly prohibited any alcoholic beverages, marinades, canned foods, mayonnaise, ketchup, soda.
It is better to eat lean beef, poultry, fish. It is better to refuse lamb and pork. The meat is best boiled or steamed.
All meals must be lean. No need to load the liver with fatty meat broths, it is better to give preference to vegetable and milk soups.
Drink more green tea, various herbal teas.
You can use any dairy products, except for the fattest ones - sour cream, cream.
Egg whites, fruits, vegetables, cereals - no restrictions.
You can not eat fresh bread, baking. It is better to consume crackers, yesterday's dried bread.
Salt and coffee increase the amount of bilirubin produced, so their consumption should be reduced to a minimum.
Drink more water to remove the hated pigment from the blood - at least three liters per day.

In addition, you need to minimize physical activity - this is also a burden on the liver. Try to avoid stress and nervous strain. Rest more, give preference to proper nutrition always, and not only in the midst of certain diseases.

Drug-induced decrease in bilirubin

To cleanse bile from the blood, gastrointestinal tract, liver and lymph, simple sorbents, such as Activated charcoal or Polysorb, are often prescribed. If liver damage is caused by herpes diseases, antiviral agents are given, for example, Acyclovir. In addition, special attention is paid to immunomodulatory and vitamin complexes that help maintain immunity at the proper level.

In addition to basic therapy, newborns are kept under an ultraviolet lamp to reduce the level of yellow pigment.

Folk remedies to reduce bilirubin

In addition, there are many recipes from herbs, vegetables and fruits that will help you speed up the process of removing bilirubin from the body.

Chamomile, St. John's wort, motherwort. Prepare a concentrated decoction of these herbs. Mix one tablespoon of each herb and pour a liter of boiling water over the collection. Let it brew for an hour, and then strain and drink the decoction throughout the day.
Beet juice. Beetroot juice will help improve liver function. Dilute the juice in half with water and drink one-third of a glass before each meal.
Birch leaves. A decoction of birch leaves will help enhance the diuretic effect. Gather the leaves and wash and dry them thoroughly. A liter jar will need a handful of such leaves. Pour boiling water over birch leaves and wrap tightly. Let it brew, then drink every 4 hours a glass of the prepared broth.
Corn silk. This component will give the body an excellent choleretic effect. In addition, a decoction of corn stigmas removes salt from the kidneys. Pour the stigmas with boiling water and leave for 5-7 hours. Drink half a glass before each meal. Keep the prepared broth in the refrigerator so that it does not ferment.
Mint and oak bark. This decoction has a powerful choleretic property, but the effect is noticeable only after long-term use. Take a spoonful of crushed oak bark and the same amount of dried mint. Pour a liter of boiling water and leave in a thermos until the morning. The next day, the broth can be filtered and drunk in a glass before bedtime. The effect of taking this remedy will be noticeable in two weeks. It is not necessary to increase the dosage of the decoction to speed up the result - this can be dangerous.
Rose hip. Rosehip decoction will help to remove bilirubin, raise immunity and improve the body's resistance. You can drink it in unlimited quantities.

Elevated bilirubin in the blood is a serious symptom that should not be ignored. If yellowness is detected on the skin and sclera, urgent hospitalization is needed and the cause of this state of the body is determined. Remember - bilirubin is very toxic, and you need to remove it from the tissues of the body as soon as possible!

Video: the whole truth about bilirubin

How to lower bilirubin

Hello dear readers. I devoted this post to bilirubin and one way in which it can be lowered. The fact is that indirect bilirubin is very toxic and therefore it is better to keep it normal.

Bilirubin is a yellow-green pigment that is formed as a result of the breakdown of hemoglobin and is found in blood serum and bile. The liver plays an important role in the metabolism of bilirubin. An increase in the level of bilirubin in the blood is accompanied by jaundice (yellowing of the sclera of the eyes, skin of the body and mucous membranes) and is most often a symptom of certain diseases of the liver (hepatitis) or blood ( hemolytic anemia).

How is bilirubin formed?

Human erythrocytes (red blood cells) contain hemoglobin, a substance that carries oxygen from the lungs to the tissues of the body. Old and damaged erythrocytes are destroyed in special cages located in the spleen bone marrow and in the liver. When an erythrocyte is destroyed, hemoglobin is released and after several chemical reactions turns into bilirubin. Bilirubin, just formed from hemoglobin (indirect bilirubin), is toxic to the body (especially to the central nervous system), so other substances “bind” bilirubin in the liver, neutralizing it. Conjugated bilirubin (direct bilirubin) is excreted by the liver as bile and leaves the body through the intestines along with feces. The dark color of feces is due precisely to the presence of altered bilirubin in it. In some diseases of the liver and biliary tract, when the release of bilirubin into the intestine is disturbed, the stool becomes colorless, like clay.

What is direct and indirect bilirubin

Serum bilirubin is divided into two fractions (varieties): direct and indirect, depending on the result of a laboratory reaction with a special reagent (diazo reagent). Indirect bilirubin is toxic bilirubin that has recently formed from hemoglobin and has not yet been bound in the liver. Direct bilirubin is bilirubin detoxified in the liver and prepared for excretion from the body.

What are the levels of bilirubin in the blood?

Determination of the level of bilirubin in the blood is carried out using a biochemical blood test. For getting reliable results it is recommended to take blood for biochemical analysis in the morning, on an empty stomach (it is important not to eat anything for at least 8 hours before taking the test). Blood for biochemical analysis for bilirubin is taken from a vein.
Normally, the content of total bilirubin (direct and indirect fractions) in the blood serum ranges from 8.5 to 20.5 µmol/l. The norm of indirect blood bilirubin is up to 17.1 µmol/l, the norm of direct blood bilirubin is up to 4.3 µmol/l.

Why is blood bilirubin elevated? Causes of an increase in the level of bilirubin in the blood

There are 3 main reasons for an increase in the level of bilirubin in the blood: increased or accelerated destruction of red blood cells, a violation of the processing of bilirubin in the liver, and a violation of the outflow of bile.

Increased destruction of red blood cells leads to an increase in hemoglobin and, accordingly, indirect bilirubin in the blood. The main cause of increased destruction of red blood cells is hemolytic anemia (hemolysis means the destruction of the blood). There are congenital and acquired hemolytic anemias. Congenital hemolytic anemias, as a rule, develop with defects in the structure of red blood cells or hemoglobin (for example, hereditary microspherocytosis, thalassemia, sickle cell anemia, etc.) Acquired hemolytic anemias are the result of autoimmune processes (when the immune system the body begins to fight with its own red blood cells), certain diseases (mayaria), taking certain medications, etc.
With hemolytic anemia, indirect bilirubin rises in the blood.
Others characteristic symptoms hemolytic anemias are:

Yellowness of the skin of the body, sclera of the eyes and mucous membranes

Discomfort in the left hypochondrium (which occurs when the spleen is enlarged - splenomegaly)

Increase in body temperature

Darkening of urine - sometimes urine can be dark brown or black, indicating intravascular destruction of red blood cells, which occurs in Marchiafava-Micheli disease (a defect in the membranes of blood cells that makes them unstable and contributes to increased destruction of red blood cells) and some other diseases.

Increased fatigue, headaches, palpitations occur due to a decrease in oxygen delivery to body tissues.

liver plays important role in the exchange of bilirubin. In liver disease, indirect bilirubin cannot be detoxified in the liver cells. Such diseases include: viral hepatitis A B C, drug-induced hepatitis, alcoholic hepatitis, cirrhosis of the liver, liver cancer, etc. With hepatitis, the level of bilirubin in the blood rises, which is manifested by jaundice and some other symptoms:

Discomfort or a feeling of heaviness in the right hypochondrium occurs with an enlarged liver

Bitter belching, nausea and discomfort after eating (especially greasy)

Weakness, decreased performance

Darkening of urine, urine may become the color of beer or strong tea, and discoloration of stools

Sometimes there is an increase in body temperature (with viral hepatitis)

There is another reason for the increase in bilirubin in the blood: a hereditary deficiency of the liver enzyme (glucuronyl transferase), which is involved in the metabolism of bilirubin, or Gilbert's syndrome. With Gilbert's syndrome, the level of indirect bilirubin in the blood is increased, which is manifested by yellowness of the skin, sclera of the eyes and mucous membranes.

Elevated bilirubin is also detected when there is a violation of the outflow of bile from the liver or gallbladder, for example, with cholelithiasis, cancer of the gallbladder or pancreas. In case of violation of the outflow of bile in the blood, direct bilirubin is increased. An increase in direct bilirubin in the blood leads to the development of jaundice. In addition to jaundice, a violation of the outflow of bile is manifested by the following symptoms:

In cholelithiasis, the development of jaundice is usually preceded by hepatic colic - an attack acute pain in the right hypochondrium.

Severe itching of the skin, which is caused by irritation nerve endings skin with bilirubin.

Belching or vomiting bitter, nausea, loss of appetite

Bloating, constipation or diarrhea.

Periodic pain in the right hypochondrium.

With a complete violation of the outflow of bile from the gallbladder, the stool takes the form of "white clay" - the feces are discolored.

Dark urine.

Bilirubin in newborns

In newborns, blood bilirubin is always elevated. The reason for this is the increased destruction of the baby's red blood cells immediately after birth. The fact is that while a child develops in utero, its red blood cells contain a special, fetal hemoglobin, which differs from the hemoglobin of adults. After birth, the body no longer needs fetal hemoglobin, and red blood cells with such hemoglobin are destroyed. Increased destruction of red blood cells leads to an increase in bilirubin in the blood and contributes to the development of physiological (normal) neonatal jaundice. Normally, the content of bilirubin in the blood of newborns on the 3rd-4th day after birth should not exceed 256 µmol/l in full-term babies and 171 µmol/l in premature babies.
When bilirubin in the blood rises excessively, pathological neonatal jaundice develops, which indicates a disease (usually hemolytic disease newborns).

Bilirubin in pregnant women.

During pregnancy, blood bilirubin is usually normal. In the last trimester of pregnancy, an increase in the level of bilirubin is sometimes noted, which indicates a violation of the outflow of bile from the liver ( intrahepatic cholestasis pregnant women). An increase in bilirubin in pregnant women requires a detailed examination, as it may indicate the presence of a disease (for example, viral hepatitis, hemolytic anemia, cholecystitis).

How to lower bilirubin?

Treatment of elevated bilirubin is possible only after establishing the cause of its increase. With increased destruction of red blood cells, it is necessary to find out the cause of hemolysis (breakdown of red blood cells) and act directly on it. In liver diseases, elevated bilirubin is only a symptom that disappears after recovery. If the cause of high blood bilirubin is stagnation of bile, it is necessary to remove the obstruction to the outflow of bile, which will lead to a decrease in the level of bilirubin. To reduce the level of bilirubin in the blood in newborns, drugs that induce (activate) liver enzymes (for example, phenobarbital) are used.

How to lower bilirubin in hepatitis

In the case of hepatitis A, bilirubin will decrease only after complete cure. To do this, it is enough to go to the infectious diseases hospital on droppers. With hepatitis C, you need to undergo antiviral treatment and after that everything will return to normal by itself. Much harder situation is the case with chronic hepatitis B. Nucleosides in this case will not affect the level of bilirubin in any way and it will decrease only in the case of interferon therapy.

AT recent times excellent tool to lower the level of bilirubin is an Italian drug. It is used in almost all infectious diseases hospitals for the purpose of sharp decline indicators for hepatitis of varying severity. But again, without a complete cure for the underlying disease, it is almost impossible to stop the level of bilirubin growth again.

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