The norm of creatinine in the blood. Reasons for the increase and decrease in creatinine. Daily excretion of creatinine in the urine. Normal level in women

This article explains the importance of controlling the concentration of creatinine in the body. The norms for its content for men, women and children are given. different ages. Methods for normalizing indicators are indicated.

AT modern world man has to lead active image life, the body works even when a person sleeps. A person breathes, his heart beats, pupils run, other systems also work. All this is due to muscle contraction, and they, in turn, need energy.

So creatinine. What is it and what is its role in the human body?

Creatinine is a nitrogenous acid, is formed in human muscle tissues and is a breakdown product of the creatine-phosphate reaction, as a result of which the energy necessary for muscle contraction is released. Creatinine is additional source energy.

The level of creatinine in the blood plasma and the rate of its excretion in the urine indicate good kidney function and the state of human health in general. Creatinine is produced in the muscles, then enters the bloodstream and is eventually excreted from the body through the kidneys in the urine. Can be depicted schematically: dietary amino acids - muscle creatine - phosphate - creatinine in blood - kidneys-urine.

The norm of creatinine healthy person is a constant value. Changes occur depending on changes in the volume of muscle mass, gender, and also the age category.

Plasma creatinine rate:

It is generally accepted that female creatinine is lower than male. This is due to the fact that the male muscle mass almost always more female, as well as metabolism. In the body of men, it proceeds much faster. women often change hormonal background especially during pregnancy. It should be said that for children, a change in the level of creatinine in the blood is the norm. In infants, creatinine is high, in children school age he falls. This is due to a decrease in metabolic rate. With the growth of the muscle mass of the child adolescence the rate of creatinine in his blood increases (see table above).

Creatinine is toxic to the body, so it must be excreted on a schedule - within a day.

Daily excretion of creatinine in the urine:

• men: 8.8-17.7 m mol (1.0-2.0 g);
• women: 7.1-15.9 m mol (0.8-1.8 g).

If this does not happen, then intoxication of the body begins.

Symptoms:

• pain when urinating, foam, changing color of urine;
• nausea, vomiting;
• girdle pain in the abdomen, lower back;
• in the urine, erythrocytes and protein, as a sign of an inflammatory process;
• bouts of hypertension.

A high plasma creatinine concentration may indicate the development kidney failure

There are a number of circumstances and prerequisites that increase the concentration of creatinine in the blood serum. The factors associated with healthy changes in the human body are called physiology.

To physiological factors relate:

• taking antibiotics;
• weight gain due to muscles, refers to professional athletes;
• protein diet- food of animal origin;
• reception medicines that relieve inflammation such as ibuprofen.
• pregnancy and lactation;
• age development of children;
• age over 65 years.

There are also a number of deviations from the norm of human health. They are called pathology.

Pathological factors include:

• diabetes;
• renal failure, urinary tract diseases;
• myocardial infarction;
• dehydration due to diarrhea;
• heart failure;
• diseases associated with dysfunction thyroid gland;
• muscle injuries and ruptures;
• viral infections of the genitourinary system;
• severe burns.

Tips to help reduce blood creatinine may also be different, depending on the reasons for its increase. If during the examination no strong deviations were found and the creatinine norm is not greatly overestimated, then follow these guidelines:

• control the diet, limit the consumption of fatty meat products;
• limit the intake of proteins, salt, potassium;
• add to food foods that help cleanse the body, antioxidants;
• protein is best obtained from food plant origin;
• eat more fiber (fruits, vegetables, cereals, bran bread);
• eliminate dehydration, drink should be plentiful, at least 2 liters per day;
• exclude tonic drinks (tea, coffee), spicy, smoked dishes;
• limit physical exercise.

If during the examination, in addition to high creatinine, other pathological factors kidney failure, liver disease, problems with endocrine system, then higher these recommendations won't be enough. It is necessary to consult a doctor of the required profile. Treatment should be carried out under the supervision of a specialist with the use of medications. Hospitalization is possible.

Low rate of creatinine in blood plasma.

Decreased serum creatinine is much less common.

Symptoms of this indicator are mild and are characterized by:

• decrease in working capacity;
• general weakness and dizziness.
• Factors for low human creatinine:
• vegetarian diet, rejection of meat products;
• muscular dystrophy
• 1-2 trimesters of pregnancy;
• anorexia, starvation.

Creatinine is a substance that is formed during the breakdown of protein molecules of creatine phosphate. The concentration of creatinine in human blood makes it possible to judge the state of muscle tissue and the degree of filtration impairment, since it is excreted from the body only with urine.

The norm of creatinine in women is 44-976 µmol / l and usually this value is constant. In the event that it decreases or increases, this may indicate certain changes that have occurred in the body.

Creatinine is the end product of protein metabolism, which is formed as a result of the breakdown of a substance such as creatine. It is creatine that takes an active part in providing all muscle cells with the necessary amount of energy. The main site of synthesis of creatine is the liver and it is from this organ that it subsequently enters the organs and is delivered to the muscles.

After that, a phosphoric acid residue is added to such a substance, and the formation of creatinine phosphate becomes a consequence of this. It is creatinine phosphate that takes an active part in the transfer of energy throughout the female body.

Creatinine in the blood is formed as follows: creatinine phosphate is cleaved from the phosphate group and this process is carried out in muscle tissue.Gradually, creatinine enters bloodstream at a constant rate and this explains the fact that in the blood plasma its amount is usually constant.

Creatinine is freely filtered in an organ such as the kidneys, and it is excreted from the body along with urine.

In the event that the concentration of such a substance in a woman's body increases, then this is one of the signs of impaired renal function. On the early stages the development of pathology, the indicator usually has minor deviations from the norm, therefore, the level is simultaneously determined.

Analysis for creatinine in women

A study on the level of creatinine in female body held in morning time. Fence in progress venous blood from the elbow zone, and in order to obtain accurate and reliable research results, it is recommended to follow some rules. Venous blood sampling is carried out 8 hours after the last meal, so an analysis for creatinine is always performed on an empty stomach.

In the event that it is necessary to conduct a study on creatinine clearance (in urine), then simultaneously with blood sampling from a vein, a urine test is performed. Urine collection should be carried out within 24 hours before the study and a large 3-liter container should be used for this purpose. It is important to remember that the first morning urination should be skipped and it should be stored in a cool place until the material is submitted for analysis.

Before conducting an analysis for creatinine clearance, it is necessary to refrain from eating the following foods for several days:

• coffee
• red meat
• alcoholic drinks
• spicy and fried foods

Another research method is, thanks to which it is possible to determine the ratio of nitrogen and creatine. Such a blood test is carried out necessarily in the morning and on an empty stomach. On the eve of the procedure, you should avoid strong physical exertion on the body and give up alcoholic beverages.

The norm of the substance in women

Exist the following reasons this difference:

1. women have lower muscle mass
2. in the female body, metabolic processes are slower
3. a diet with a low content of exogenous creatinine predominates
4. women have lower muscle activity
5. female sex hormones, estrogen, are present in the body

Among women normal it is considered 53-97 µmol / l, and with age this indicator increases.

So, if in girls from 1 to 6 years old, 31-52 µmol / l is considered the norm, then by the age of 20 and older, the level of such a substance rises to 50-98 µmol / l. AT childhood the indicator of such a substance will be much lower than in adult women.

In addition, the concentration of creatinine decreases significantly during pregnancy and especially in the second and third trimester.

The reasons for this phenomenon lie in the fact that the total volume of blood increases and plasma filtration in the kidneys increases.

Reasons for increasing the substance

The reasons for the increase in the level of creatinine in the female body, first of all, should be looked for in physiology. The fact is that the concentration of such a substance is often increased in those people who are actively involved in power sports. This usually applies to bodybuilding, since such a sport is accompanied by the use of anabolic hormonal drugs. The result of this is the fact that a blood test shows an increase in decay products.

Can cause an increase in creatinine in the female body various diets that require limiting the intake of carbohydrates and fats. strict diets and hunger lead to the fact that the metabolic process in the body is disrupted and the result is a decrease. At the same time, with such indicators, there is an increase residual nitrogen creatinine and urea.

The reason for a significant increase in creatinine in the female body are various processes destructive action that occur in muscle tissues:

• injury different nature that cause tissue compression for a long time
• surgical interventions
• high degree burns
• breakdown of a malignant neoplasm
• myocardial infarction with necrosis of the heart muscle
• severe bleeding, diarrhea and vomiting copious loss liquids

It is possible to talk about problems with the work of the kidneys only with a simultaneous increase in the content of creatinine and a decrease in filtration rates in the urine under study. The kidneys are characterized by a certain supply of tissue and damage to part of the organ does not affect the state of health.

More information about creatinine can be found in the video:

Active work is a pathology in which the process of disintegration of muscle tissue begins due to increased production. The fact is that such hormones cause muscle breakdown and a woman begins to lose weight quickly.

To reduce the level of creatinine in the body, it is recommended:

1. avoid stressful situations and nervous tension
2. reduce the amount of physical stress on the body
3. drink enough fluids throughout the day
4. reduce protein intake
5. sleep well
6. eat less sodium-rich foods

Traditional medicine suggests drinking to reduce creatinine green tea, which is considered a good diuretic and helps to normalize kidney function. Besides, good effect gives tea from sage and nettle.Changes in creatinine levels in the body of women may be dangerous signal but don't panic right away. It is necessary to visit a specialist and pass an analysis to identify the level of such a substance in the body.

Decrease in indicators

A decrease in creatinine levels is considered normal if a woman is pregnant. This happens for the reason that the volume of blood increases and the filtration of the kidneys increases. Mostly this phenomenon occurs in the second or third trimester of pregnancy.

In medicine, the insufficient content of creatinine in the blood plasma is called hypocreatinemia. Such a pathological condition is not detected so often and its presence is not a symptom of any disease in the female body. The main cause of hypocreatinemia is serious problems with muscle and protein metabolism.

Cause a decrease in the concentration of creatinine in the female body can:

• rigid diets that cause severe depletion of the body
• cachexia provoked by pathologies chronic nature or fasting
• amyotrophy
• taking glucocorticoids and other medications

In some cases reduced level creatinine is detected in the elderly and amputees.

Creatinine is the final step in the breakdown of creatine phosphate, which is the basis for energy production in the body. This substance is synthesized in muscle tissues. It is formed in the liver and kidneys from amino acids and, released into the blood, spreads to muscle tissues. Excreted with urine.

Cretinin is the final product of degradation reactions. Not used for further metabolism. It is a harmful compound and must be completely eliminated from the body. Violations can occur during synthesis, metabolic process and withdrawal.

Creatinine is an indicator of kidney function and indicates the ability to excrete waste products. Hence the need to check the state of creatinine in the blood. A high level of creatinine speaks, first of all, about problems with the kidneys. This leads to an increase in the content of a harmful substance in the blood, which can affect the work of other organs. Therefore, it is so important to maintain normal creatinine in the blood. With a small content in the blood does not cause harm.

1. Floor. In women, the figure is lower than in men and depends on the amount of muscle mass.
2. Age. During the period active growth in children and adolescents, creatinine levels rise. This is due to the need to build muscle mass. In older people, creatinine levels decrease.
3. Physical exercise. Since creatinine is an energy substance, its content increases with high volumes of physical activity. In people with in a sedentary manner life this indicator short.
4. The amount of muscle mass. In men, blood creatinine is significantly higher than in women.
5. Hormonal background. It applies primarily to women. Any hormonal changes including pregnancy increase the intensity of protein metabolism.
6. Food. The presence of a large amount of protein foods in the diet leads to an increase in creatinine in the blood. Long term failure from food leads to a drop in energy and substance in the blood.
7. Use of food supplements containing creatinine.

Creatinine analysis

Problems for which it is necessary to take a creatinine test:

1. Diseases of the genitourinary system.
2. Damage to muscle tissue.
3. A high percentage of burns.
4. Diseases of the thyroid gland.
5. Diabetes.
6. Diseases of the cardiovascular system.
7. Intestinal obstruction.
8. Dystrophy.

How to take an analysis

To receive you need to reliable results must be respected certain rules before taking a blood test for creatinine:

The norm of creatinine in the blood in women is 45-80 µmol/l, in men 75-110 µmol/l, in children 6-18 years old 28-63 µmol/l and in children up to a year 46-106 µmol/l, from one year to 14 years 26-65 µmol/l, 14-16 50-95 µmol/l.

Paying attention to the fact that creatinine is excreted from the body with urine, the daily volume of the excreted substance in the urine is up to 2 g.

Elevated creatinine in the blood

Hypercreatininemia - an increase in the level of cratinin in the blood.

If a metabolite growth is detected, it is necessary to correctly read the test results in accordance with the physiological, age, and sex characteristics of the organism.

An increase in the amount of this substance in the blood is caused by its increased formation and a decrease in the body's ability to excrete. To given state lead:

1. Abrupt changes in liver function ( obstructive jaundice, liver atrophy).
2. Disorders in the work of the cardiovascular system.
3. Changes in lung function inflammatory processes, fever.
4. Intestinal obstruction.
5. Damage to the kidneys, urinary tract, which leads to a violation of the outflow of urine.
6. Increased synthesis of growth hormone.
7. Diabetes caused by hormonal imbalance.
8. Lots of physical activity.
9. Pregnancy.
10. Inhibition of the adrenal glands.
11. Oncology of muscle tissue.
12. The use of drugs that have a toxic effect on the kidneys.
13. Dehydration of the body.
14. Toxicosis during pregnancy.

Hypercreatininemia causes deviations in the work of the body only with sharp deviations from the norm. In most cases increased content substances is a sign of the presence of diseases in conjunction with other signs:

1. Pain in the muscles.
2. fatigue.
3. Edema.
4. Drowsiness.
5. The rhythm of breathing quickens or becomes less frequent.
6. Depression.
7. Decrease (growth) in the volume of daily urine.
8. Abnormalities in urinalysis.

Methods of dealing with hypercreatininemia

In cases where creatinine has increased slightly, first of all, it is necessary to determine the cause of the increase and correct the lifestyle. For this purpose, you need:

1. Do research internal organs and muscle tissue.
2. Adhere to proper nutrition, a special diet.
3. Change in the amount of water consumed.
4. Make adjustments to physical activity.
5. Give up smoking.
6. Methods can be used traditional medicine. Diuretic teas from nettle, sage, cranberries, rose hips, chamomile, mint.

Diet for high creatinine

The diet involves the rejection of a large amount of protein food, especially protein of animal origin. Restriction of potassium and salt. They help retain fluid in the body.

Stop using:

1. Fatty meat.
2. Fatty fish.
3. Milk.
4. Products based on yeast, baking.
5. Fried food.
6. Smoked food.
7. Spicy meals.
8. Seasonings, salt and sugar.

Restrict:

1. Meat of dietary varieties (no more than 2-3 times a week).
2. Chicken eggs up to three pieces per week.
3. Low fat fish.

Increase the amount in the diet:

1. Fresh fruits and vegetables.
2. Berries, compotes.
3. Nuts, dried fruits.
4. Dairy products.
5. Vegetable oil.
6. Macaroni and wholemeal bread.

Cooking should be steamed or boiled.

In the case when cretinin has reached a critical level:

1. Hospital treatment is prescribed.
2. Taking medications that affect protein metabolism.
3. The final measure is an artificial kidney.

Decreased creatinine

Quite rarely, a decrease in cretinin in the blood occurs. This also indicates violations of metabolic processes in the body that are associated with protein metabolism.

Creatinine levels fall below normal:

1. During pregnancy, in the first and second trimesters, when the body is being restructured.
2. Prolonged refusal to eat.
3. Vegetarians.
4. In people with a lack of muscle mass.
5. The use of corticosteroid drugs.
6. During the aging process.

In addition, the deviation of the level of creatinine from the norm downwards may indicate the presence of diseases:

1. Anemia.
2. Atrophy of muscle tissue.
3. Paralysis.
4. Dermatomyoitis.
5. Leukemia.

To timely determine the increase in the substance in the blood at the first symptoms, it is necessary to consult a doctor and donate blood for creatinine. In men, the norm of creatinine is always higher than in women, this is primarily due to physiological features. In order to maintain creatinine in the blood within the normal range, it is necessary to exercise regularly. exercise and eat right.

Creatinine is a product of energy metabolism in muscles. It is formed during the creatine phosphate reaction, by releasing the energy needed to contract the fibers. In the blood, the level of the compound has a constant normal value. Changes occur under the influence of various physiological and pathological factors.

Creatinine - what is it, its metabolism in the body

The main reserve source of energy needed for muscle contraction is creatine phosphate. When muscle fibers contract, enzymatic breakdown of creatine phosphate into creatinine and phosphate occurs, and energy is released. In the future, the substance from myocytes (muscle cells) enters the bloodstream and is excreted by the kidneys with urine.

The norm of creatinine in the blood is a fixed indicator that fluctuates under the influence of physiological or pathological factors. Its level is higher in men, which is associated with a large amount of muscle mass. Normal indicators:

• in children up to a year - 18-36 µmol / l;
• at the age of up to 14 years - 25-65 µmol / l;
• in women - 52-98 µmol / l;
• in men it is much higher - 82-116 µmol / l.

Causes of increased creatinine in the blood

There are physiological and pathological factors that cause an increase in creatinine. The first are not associated with diseases:

• muscle mass - the greater the volume of muscles, the higher the creatinine, therefore, in athletes, the indicator is within the upper limit of the norm or exceeds it;
• increased physical activity - in the blood, creatinine is increased due to the intensive breakdown of creatine phosphate during muscle work;
• diet with great content a protein that increases the exogenous intake of creatinine into the blood;
• drugs (tetracycline antibiotics, cephalosporins, anti-inflammatory drugs) - in the process of biochemical transformations active ingredients creatinine is produced and released into the blood.

The pathological causes of high creatinine are increased intake from the muscles or slow excretion of the substance by the kidneys. Provoking factors:

• diseases that cause kidney failure (acute or chronic) - pyelonephritis, toxic injury, infections prevent the excretion of the substance in the urine;
• circulatory disorders, heart failure, low blood pressure in the glomeruli of the kidneys, they slow down the filtration of primary urine (glomerular filtration) and the excretion of creatinine;
• hyperthyroidism - increased production of thyroid hormones, which increase the basal metabolism and breakdown of creatine phosphate;
• malignant neoplasms that grow into muscle tissue (penetration) with its damage;
• muscle tissue injuries (long compression, necrosis, III or IV degree burns) - creatinine is released from damaged myocytes, its level increases;
• radiation sickness - under the influence of ionizing radiation, all cells are gradually destroyed and muscle tissues organism.
• dehydration - a decrease in the volume of the liquid part of the blood due to a deficiency or increased excretion of fluid. Creatinine rises due to an increase in its concentration in a reduced plasma volume.

Signs of elevated creatinine

The clinical picture with an increase in creatinine is blurred. The patient's condition is often associated with colds due to the similarity of symptoms:

• muscle pain;
• fatigue, high fatigue;
• swelling of the soft tissues of the legs, arms, face;
• a noticeable change in the volume of urine excreted per day up or down.

Causes of a decrease in creatinine

Low level biochemical indicator diagnosed less frequently. The decrease is observed in situations:

1. vegetarianism - little creatinine enters the body with food;
2. pregnancy - in the I and II trimester, the volume of blood and the vascular bed increases due to hormonal adjustment, while creatinine decreases slightly;
3. muscular dystrophy - delayed muscle development (genetic abnormalities, malnutrition or chronic pathology), which reduces the flow of creatinine into the blood from myocytes.

Determination of the level of creatinine in the blood

To determine the level of creatinine, a biochemical blood test is performed. In order for the results to be reliable, on the eve of the analysis, it is necessary to follow a number of recommendations:

• give up meat alcoholic beverages the day before the examination;
• avoid physical activity;
• maintain emotional calm on the day of the examination.

Clearance - what does it mean?

To identify the cause advanced level creatinine clearance is assessed. This indicator shows the rate and volume of excretion of a substance by the kidneys (rate glomerular filtration). In the course of the study, the concentration of creatinine in the urine per day is determined. The patient during the day collects urine in one dish.

Today, a single biochemical analysis is more often carried out to determine the concentration of creatinine in the blood, and a special formula is used to calculate the clearance, taking into account the weight and age of the subject. Low clearance means a decrease in glomerular filtration with the development of renal failure.

how to lower creatinine

Basic treatment of the condition involves eliminating the cause of the pathology.

Folk methods for reducing creatinine

lower creatinine folk remedies possible, provided that the kidneys are functioning normally. Use teas based on diuretic medicinal herbs:

• nettle;
• sage;
• dandelion root.

Any herb is poured with boiling water in the ratio of 20 g of dry herbs per 300 ml of liquid. Infuse tea in a thermos for 1-2 hours, then drink 100 ml three times a day.

Lowering creatinine is easy by eating a serving for breakfast boiled rice without additives. In the evening, grits are poured with water so that it swells. In the morning put on a slow fire without changing the water.

Before treatment, it is necessary to consult a doctor, find out the cause of the deviations, exclude violations in the work of the kidneys with a decrease in glomerular filtration.

For any movement muscles require synthesis reactions, with the help of which creatine is formed, then creatine phosphate, which will give the right energy upon splitting, the residual component - creatinine - enters the bloodstream and is excreted from the body through the kidneys.

Its quantity is always within certain norm, deviations from which are a symptom of pathology.

Blood creatinine level when the patient complains, doctors check for muscle pain, swelling, frequent urination when diagnosing disorders in the work of the kidneys. Because it's in the blood always present, its amount fluctuates slightly, but there are maximum allowable values ​​for men, women and children, as well as for age groups. And serious deviations from the norm - clear sign the presence of a disease or pathology.

Learn about content creatinine can be biochemical analysis blood, and kidney samples when the blood is checked for creatinine, urea nitrogen and electrolytes.

It is the liquid running through the veins, and not urine, that is able to tell in the most detailed way about whether it is functioning normally. excretory system, are output through the kidneys from tissues and organs, non-protein nitrogenous components, products of cleavage and decay reactions of many amino acids, enzymes, hormones that can cause serious harm health.

Specifically, creatinine analysis is prescribed for chronic renal failure in order to assess the performance of the kidneys, or already for the appointment of hemodialysis.

Levels can be determined by nutrition, the amount of liquid you drink, the intake of dietary supplements, the strength and duration of physical activity, and the time of day. The lowest morning creatinine in the evening can double, while remaining within acceptable limits.

And if low creatinine is extremely rare and speaks of muscle dystrophy, atrophy of some of their groups due to diseases, exhaustion, can be recorded in the first months of pregnancy, then high is very alarming.

In itself, the content of creatinine is not a disease, therefore, it is impossible to take any action to increase or decrease it in any case, it can be life-threatening. Moreover, for clarification, it is recommended to take tests more than once.

When creatinine is detected in the blood 40 - 100 µmol/l higher normal values the doctor necessarily sends the patient for re-analysis, already with strict observance of all the rules: in the morning, it is better on an empty stomach, without previously undergoing physical exertion. It is advisable to do a urine test, a decrease in the metabolite in it will confirm the presence of problems with the kidneys.

Temporary Boost creatinine is fixed:

• when taken biologically active additives such as Vanadium Bio, Creatine to change metabolism;
• with dehydration;
• with a diet that includes a large number of protein, fatty meat;
• when building muscle mass.

Deviations from the norm may cause some medications, so the doctor must also be informed about which medications or drugs the patient began to take shortly before the test. This will help to choose the right method of examination, to make an accurate diagnosis.

How can I lower the level?

Pro chronic diseases it is very important to reduce creatinine to normal in a timely manner. An important aspect this is proper nutrition, because many foods can provoke kidney failure.

Need to reduce consumption of protein-rich foods. It is advisable to exclude not only meat, but also legumes, including beans, dairy and fish meals, egg. Diet at chronic diseases only a doctor can prescribe, severe restrictions are rarely required. Fish, lean meat, foods containing vegetable protein do not increase the burden on the kidneys too much, so, if you observe the measure, you can not completely exclude them.

Limit consumption salt: it retains fluid in the body and leads to an increase in pressure. This also leads to an increase in creatinine.

Control the amount of foods rich in phosphorus and potassium in the diet, which increase the load on the kidneys, eventually disrupting the filtration process and increasing the level of creatinine in the blood.

Water must be present at required quantity. Dehydration is extremely dangerous for many functions, it can dramatically increase creatinine, but the intake of more than 3 liters of fluid in the body can seriously damage the kidneys.

Experienced nutritionists who help patients say that changing the diet will not help to quickly and drastically reduce this indicator, but a person will have the opportunity control creatinine.

To improve performance, many weightlifters and professionals take supplements that contain creatine. It is considered harmless, it is not banned for world-class competitors, but it is worth remembering that creatinine is a breakdown product of creatine, and completely can't be harmless.

Rest is also essential for those whose creatinine levels are high. It is necessary to observe the daily regimen, sleep at least 8 hours, so that not only the brain, but also the muscles rest. AT calm state Creatine breaks down much more slowly, not allowing excess creatinine to end up in the blood, allowing the kidneys to excrete it almost completely.

Improve blood flow, the speed of its filtration will help massage, warm baths with soothing and relaxing herbs, sea salt.

Discuss with your doctor the medications you are taking for treatment of chronic diseases. Ibuprofen, cyclosporine, some hormonal drugs can increase creatinine. It is better to replace them with less dangerous analogues.

If creatinine rises at diabetes, usually type 2, you must take insulin as prescribed by your doctor. This will stop the process of destruction of the kidneys. You need to talk about the dosage with an endocrinologist, because this drug is vital.

Pressure also needs to be controlled, reducing it to working level with medication.

Often preventive measures help people control the quality of their blood, preventing it from accumulating harmful substances and avoiding slow poisoning of the body.

Creatinine in the blood of men

For the stronger sex level creatinine 75 - 115 µmol/l considered normal. But when taking tests, it is necessary to pay attention to the reference values ​​that are necessarily indicated in laboratories so that the patient does not get confused in the features of the technologies and reagents of each of them. Average, extremely low and high numbers for the norm will help you understand if everything is normal. And if there is a deviation, immediately consult a doctor.

High performance creatinine in the blood of men is due to greater muscle mass, greater physical exertion, so the upper limit can fluctuate by 10-15% if a person is seriously involved in weightlifting, powerlifting, if there is a lot of protein in the diet.

older men, as a rule, are faced with a decrease in creatinine levels, because muscle mass becomes smaller. Therefore, the results of the analyzes must be interpreted on the basis of age.

Exhaustion, feeling tired, shortness of breath, pain in the lower back, high pressure and difficulty urinating (urine is not passed or the urge has become too frequent) - most common symptoms kidney problems in men causing an increase creatinine.

Normal level in women

For women, indicators are considered normal 55 to 100 µmol/l. Blood should be especially seriously monitored during pregnancy, during which the level should decrease slightly. Raising is fraught with serious problems for mom and fetus, can talk about kidney failure or other diseases pathological conditions, which caused an increase in creatinine at any stage of metabolism from synthesis in the liver and breakdown in muscles to hematopoietic systems, the excretory system.

Women at high creatinine complain about headache, difficulty concentrating, oxygen starvation, loss of appetite, swelling, muscle pain.

The diseases that are detected during the examination are very serious and require a long, sometimes lifelong treatment.

Common causes of excess

Among causes of increased creatinine protein diet, fast growth muscle mass, serious physical activity, taking certain medications and hormonal drugs, dietary supplements.

But this symptom is also observed in diseases such as

• diabetes;
• disorders in the work of the kidneys;
• hyperthyroidism;
• acromegaly.

This list is far from complete. Like on its own increase in creatinine, these diseases lead to sad consequences and do not go away on their own.

Only treatment of the underlying disease, lifestyle change and following all the recommendations of doctors will help to avoid life-threatening complications.

What treatment is required?

There are remedies for lowering creatinine.

• Ketosteril is now one of the best drugs. Take 4 to 8 tablets 3 times a day with meals if prescribed by a doctor. Supplements with alpha lipoic acid, which neutralizes toxins, which is creatinine, will help to reduce the level.
• In a hospital setting if the result of the analysis for creatinine is negative, doctors prescribe detoxification procedures: sorbents that purify the blood are injected into the body using a dropper intravenously. It also greatly facilitates the well-being of patients.
• In the most difficult cases when we are talking about life, doctors use hemodialysis - blood transfusion to cleanse it of toxins, or perineal dialysis. The indications for this costly and complex procedure are blood test results showing high level urea nitrogen, creatinine, as well as the same level of creatinine in urine and blood. With kidney failure passed into chronic stage , some other diseases need dialysis for life.

The decision to prescribe treatment can only be made by a doctor, taking into account many factors. Self-medication is dangerous and unacceptable.