Rennie recipe in Latin. Rennie - instructions for use, reviews, analogs and forms of release (chewable tablets) drugs for the treatment of heartburn and symptoms of dyspepsia in adults, children and pregnancy. Compound. Contraindications for admission, side effects

Hipp GmbH & Co.Export KG Laboratoires ROCHE-NICHOLAS ROCHE Bayer Bitterfeld GmbH Bayer Sante Familial Delpharm Gayard Roche Laboratory Nicolas F.Hoffmann-La Roche Ltd (Switzerland)/Roche

Country of origin

Germany France Switzerland

Product group

Digestive tract and metabolism

Biologically active additive (BAA) to food

Release forms

  • 10 sachets in a pack 6 - blisters (2) - packs of cardboard. 6 - blisters (2) - packs of cardboard. 6 - blisters (2) - packs of cardboard. . 6 - blisters (16) - packs of cardboard. 6 - blisters (2) - packs of cardboard. 6 - blisters (4) - packs of cardboard. 6 - blisters (6) - packs of cardboard. 6 - blisters (8) - packs of cardboard. 6 - blisters (4) - packs of cardboard 6 - blisters (4) - packs of cardboard. 6 - blisters (4) - packs of cardboard. tablets - 6 - blisters (4) - cardboard packs. tablets - 6 - blisters (4) - cardboard packs. pack of 12 chewable tablets pack of 12 tablets pack of 24 tablets pack of 48 tablets pack of 48 tablets

Description of the dosage form

  • Chewable tablets cooling taste granules in a sachet, dissolve in the mouth in 30 seconds. Chewable (orange) tablets, white, creamy, square, with concave surfaces, engraved "Rennie" on both sides, with orange flavor Chewable tablets (orange), white, creamy, square, with concave surfaces, engraved "Rennie "on both sides, with the smell of orange. chewable tablets [orange] Chewable tablets, white, creamy, square, with concave surfaces, engraved with "Rennie" on both sides, with a menthol odour. Sugar-free mint chewable sugar-free white, creamy, square, concave mint tablets, engraved "Rennie" on both sides, mint flavor Sugar-free white, creamy, square, concave mint tablets , engraved with "Rennie" on both sides, mint scented.

pharmachologic effect

Heartburn drug. Quickly helps (3-5 minutes), protects the mucous membrane of the stomach and esophagus, contains substances natural for the body (calcium and magnesium). Antacid preparation of local action. Rennie's tablet contains antacid substances - calcium carbonate and magnesium carbonate, which provide a quick and long-term neutralization of excess hydrochloric acid of gastric juice, thereby providing a protective effect on the gastric mucosa. Achieving a positive effect within 3-5 minutes is due to the good solubility of the tablets and the high content of calcium.

Pharmacokinetics

Absorption As a result of the interaction of Rennie® with gastric juice, soluble calcium and magnesium salts are formed in the stomach. The level of absorption of calcium and magnesium from these compounds depends on the dose of the drug. The maximum level of absorption is 10% calcium and 15-20% magnesium. Excretion Small amounts of absorbed calcium and magnesium are excreted by the kidneys. In the intestine, soluble salts form insoluble compounds that are excreted in the feces. Pharmacokinetics in special clinical situations In case of impaired renal function, the level of calcium and magnesium concentration in plasma may increase.

Special conditions

Patients with impaired renal function are not recommended to take the drug for a long time in high doses. When prescribing the drug to patients with impaired renal function, the concentration of magnesium and calcium in the blood serum should be regularly monitored. The use of Rennie® in high doses may increase the risk of kidney stones. If it is necessary to prescribe the drug to patients with diabetes mellitus, it should be borne in mind that 1 tablet of Rennie® with the smell of menthol and 1 tablet of Rennie® with the smell of orange contain 475 mg of sucrose. 1 tablet of Rennie® with mint flavor contains 400 mg of sorbitol and saccharin and can be administered to patients with diabetes mellitus. If treatment fails, the patient should consult a doctor. Influence on the ability to drive vehicles and control mechanisms The drug does not affect the ability to drive vehicles and other activities that require a high concentration of attention and speed of psychomotor reactions.

Compound

  • calcium carbonate 680 mg magnesium hydroxycarbonate 80 mg Excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, liquid paraffin, orange flavor (orange oil, maltodextrin, purified water), sodium saccharinate. Calcium carbonate (calcium carbonate, maltodextrin), sweetener xylitol, magnesium carbonate, cooling flavor (malonic acid diethyl ester, maltodextrin (maize), menthol, menthyl lactate, modified starch carrier E1450 (waxy maize), isopulegol), mint flavor (maltodextrin (maize), menthol, carrier modified starch E1450 (waxy maize)), sweetener sodium saccharinate. calcium carbonate 680 mg magnesium hydroxycarbonate 80 mg Excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, light liquid paraffin, menthol flavor, lemon flavor. calcium carbonate 680 mg magnesium hydroxycarbonate 80 mg Excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, liquid paraffin, orange flavor (orange oil, maltodextrin, purified water), sodium saccharinate. calcium carbonate 680 mg magnesium hydroxycarbonate 80 mg Excipients: sorbitol, pregelatinized corn starch, potato starch, talc, magnesium stearate, light liquid paraffin, mint flavor, sodium saccharinate. calcium carbonate 680 mg magnesium hydroxycarbonate 80 mg Excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, liquid paraffin, orange flavor (orange oil, maltodextrin, purified water), sodium saccharin calcium carbonate 680 mg magnesium carbonate basic 80 mg Excipients: sucrose 475 mg, pregelatinized corn starch 20 mg, potato starch 13 mg, talc 33.14 mg, magnesium stearate 10.66 mg, light liquid paraffin 5 mg, xylitab 100 (xylitol (min 95% ), polydextrose) 25.2 mg, cooling flavor (diethylmalonate, maltodextrin, menthol, methyl lactate, modified starch E1450, isopulegol) 15 mg, menthol flavor (maltodextrin, menthol, modified starch E1450) 15 mg. calcium carbonate 680mg; magnesium carbonate 80mg; Auxiliary substances: sucrose, pregelatinized corn starch, potato starch, magnesium stearate, talc, menthol flavor

Rennie indications for use

  • Symptoms associated with increased acidity of gastric juice and reflux esophagitis (including those caused by errors in diet, medication, alcohol, coffee, nicotine abuse): - heartburn; - belching; - periodic pain in the stomach; - feeling of fullness or heaviness in the epigastric region; - flatulence; - dyspepsia. Dyspepsia in pregnancy.

Rennie contraindications

  • Severe renal failure, hypercalcemia, hypersensitivity to the components of the drug. Application during pregnancy and lactation When used in recommended doses, the drug does not pose a danger to the fetus or child.

Rennie dosage

Rennie side effects

  • Subject to the recommended doses, the drug is well tolerated, however, allergic reactions are possible: rash, Quincke's edema, anaphylactic reactions. Long-term use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia

drug interaction

Changes in gastric acidity caused by taking antacids can lead to a decrease in the rate and extent of absorption of other drugs taken at the same time, so drugs should be taken 1-2 hours before or after taking antacids. With the simultaneous use of antacids reduce the absorption of tetracycline antibiotics, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, phosphates, fluorides. With the simultaneous use of Rennie® with thiazide diuretics, the concentration of calcium in the blood serum should be regularly monitored.

Storage conditions

  • keep away from children
Information provided

INSTRUCTIONS

on the medical use of the drug

Registration number:

Trade name of the drug:

RENNIE ®

International non-proprietary name:

Dosage form:

chewable tablets

Description:

white with a creamy tinge, square tablets with concave surfaces, engraved "Rennie" on both sides, with a menthol odor.

Compound:

1 tablet contains
active substances: calcium carbonate 680 mg
magnesium carbonate basic 80 mg
excipients: sucrose (475 mg), pregelatinized corn starch, potato starch, talc, magnesium stearate, light liquid paraffin, menthol flavor, lemon flavor.

Pharmacotherapeutic group:

antacid.

ATX:

A02AX

Pharmacological properties

The preparation contains antacid substances - calcium carbonate and magnesium carbonate, which provide fast and long-term neutralization of excess hydrochloric acid of gastric juice, thereby having a protective effect on the gastric mucosa. Achieving a positive effect within 3-5 minutes is due to the good solubility of the tablets and the high content of calcium.

Pharmacokinetics

As a result of the interaction of Rennie with gastric juice, soluble salts of calcium and magnesium are formed in the stomach.

The level of absorption of calcium and magnesium from these compounds depends on the dose of the drug. The maximum level of absorption is 10% calcium and 15-20% magnesium. A small amount of absorbed calcium and magnesium is excreted through the kidneys. In case of impaired renal function, the level of calcium and magnesium concentration in plasma may increase. In the intestine, soluble salts form insoluble compounds that are excreted in the feces.

Indications for use:

Symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, belching, recurrent pain in the stomach, feeling of fullness or heaviness in the epigastric region, flatulence, dyspepsia (including those caused by errors in diet, medication, abuse alcohol, coffee, nicotine), dyspepsia of pregnant women.

Contraindications:

Severe renal failure, hypercalcemia, hypersensitivity to the components of the drug.

Use during pregnancy and lactation.

Dosage and administration:

Adults and children over 12 years of age: unless otherwise recommended by the doctor, when symptoms appear, chew 1-2 tablets (or keep in the mouth until completely resorbed). If necessary, you can repeat the drug after 2 hours. The maximum daily dose is 16 tablets.

Side effect

Overdose

Long-term use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which are manifested by nausea, vomiting, muscle weakness. In this case, you should stop the drug and immediately consult a doctor.

Interaction with other drugs

Medications should be taken 1-2 hours before or after taking antacids. Tetrachiline antibiotics, fluoroquinolones, phosphates - with the simultaneous use of Reiki reduces the absorption of these drugs.

special instructions

Patients with impaired night function are not recommended to take the drug for a long time in high doses.
When prescribing the drug to patients with impaired renal function, the concentration of magnesium and calcium in the blood serum should be regularly monitored.
High doses of rhenium may increase the risk of kidney stones. Indication for patients with diabetes mellitus: 1 tablet of RENNIE contains 475 mg of sucrose. If the use of the drug is ineffective, you should consult a doctor for advice.

Influence on the ability to drive a car and moving mechanisms.

Does not affect.

Release form:

6 tablets in a heat-sealed aluminum/PVC blister. On 2, 4, 6, 8 and 16 blisters together with the application instruction in a cardboard pack.
12 tablets in a heat-sealed aluminum/PVC blister. On 1, 2, 3, 4 and 8 blisters together with the application instruction in a cardboard pack.

Storage conditions:

Store at a temperature not exceeding 25 ° C, out of the reach of children.

Best before date:

5 years
Do not use after the expiration date stated on the packaging.

Conditions for dispensing from pharmacies:

Without recipe.

Manufacturing firm:

Bayer Consumer Core LG (Switzerland), produced by Bayer Sante Familial, France
Manufacturer's registered address:
Bayer Sante Familial, F-74240, rue d'Ypdyustry 33, France.

Additional information can be obtained from the address:
129010, Moscow, Grokholsky per. 13, p.2.

Rennie is an antacid that neutralizes excess hydrochloric acid of gastric juice, which has a protective effect on the gastric mucosa.

The active components of the drug are calcium and magnesium carbonate. These compounds, getting into the cavity of the stomach, interact with hydrochloric acid, which is part of the gastric juice. As a result of a chemical reaction, the acid is neutralized with the formation of water and water-soluble salts of calcium and magnesium.

In this article, we will look at why doctors prescribe Rennie, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Rennie can be read in the comments.

Composition and form of release

White sugar-free chewable tablets (mint, orange or cooling flavor) with a creamy tint, biconcave, square, engraved with the word "RENNIE" on both sides.

  • The composition of one Rennie tablet includes: 680 mg of calcium carbonate, 80 mg of magnesium hydroxycarbonate.

Clinico-pharmacological group: antacid drug.

What helps Rennie?

The drug, as indicated in the instructions, can be prescribed for symptoms caused by reflux esophagitis and hyperproduction of hydrochloric acid in the stomach:

  • heartburn;
  • sour belching;
  • pain syndrome, heaviness in the stomach and epigastric area;
  • dyspeptic syndrome (in particular, with errors in diet, excessive alcohol consumption, taking certain medications).

Rennie is also used in cases of symptomatic treatment of painful gastric manifestations that occur against the background of a disturbed diet, alcohol abuse, smoking, and treatment with drugs that have a negative effect on the gastric mucosa.


pharmachologic effect

Rennie contains antacid substances - calcium carbonate and magnesium carbonate, which provide fast and long-term neutralization of excess hydrochloric acid of gastric juice, thereby having a protective effect on the gastric mucosa.
Achieving a positive effect within 3-5 minutes is due to the good solubility of the tablets and the high content of calcium. As a result of the interaction of rennie with gastric juice, soluble calcium and magnesium salts are formed in the stomach.

Instructions for use

According to the instructions for use, Rennie recommends chewing or holding chewable tablets in the mouth until completely dissolved.

  • Adults and children over the age of 12 with the onset of symptoms 1-2 tab. should be chewed (or kept in the mouth until completely dissolved).

If necessary, you can repeat the drug after 2 hours. The maximum daily dose is 11 tab.

Contraindications

The instructions for this antacid indicate that Rennie is not recommended for use in the following cases:

  1. hypercalcemia;
  2. hypophosphatemia;
  3. Nephrocalcinosis;
  4. Alkalosis;
  5. The patient's age is up to 12 years;
  6. kidney failure;
  7. Fructose and sucrose intolerance;
  8. Hypersensitivity to components.

If the patient has a suspicion of the above diseases or conditions, then it is necessary to inform the doctor about this, otherwise serious consequences are possible.

Side effects

  • In rare cases, in the presence of hypersensitivity to the components of the drug, the development of hypersensitivity reactions (Quincke's edema, rash, anaphylactic reactions) may occur.

In patients with impaired renal function, long-term use of the drug in high doses can cause alkalosis, hypercalcemia, hypermagnesemia, manifested by muscle weakness, vomiting and nausea. If such undesirable effects occur, it is necessary to stop therapy and seek advice from your doctor.

Analogues

The most famous analogues of Rennie: Almagel, Alumag, Gastal, Maalox, Secrepat Forte.

Prices

The average price of RENNIE in pharmacies (Moscow) is 180 rubles.

Terms of dispensing from pharmacies

The drug is approved for use as a means of OTC.

Rennie's tablets have been used for years to get rid of the unpleasant symptoms of heartburn. How did they gain such popularity and who can take them?

Release form

First of all, it is worth mentioning in what pharmaceutical form this heartburn remedy exists. Rennie is available without a prescription and it will not be difficult to find it for free sale at any pharmacy. This preparation is made in the form of fast-acting, pleasant-tasting chewable tablets. There are tablets with a cooling effect and menthol flavor, and there is a fruit flavor with an orange smell. The drug does not contain sugar, therefore it is suitable for people with sucrose intolerance, and also makes it possible to take Rennie during pregnancy.

Mechanism of action

The active components of Rennie interact with the main component of the gastric environment, hydrochloric acid. The combination of calcium and magnesium carbonates, which are rich in the composition of the drug, help reduce the acidity of the stomach, and, accordingly, remove the main cause of heartburn symptoms. Due to its release form and active ingredients, the tablets begin to act very quickly. Already a few minutes after taking, the salts contained in the tablet react with stomach acid. The composition of the drug has a long-term effect.

Indications for use

Rennie, whose instruction indicates a very wide spectrum of action, is to be used not only for symptoms of heartburn, but also for other manifestations of diseases of the digestive system. In general, the reasons for taking this drug can be divided into two subgroups. The first includes those associated with an increase in acidity in the stomach. These are heartburn, dyspepsia, and stomach pain associated with acute and chronic diseases of the digestive system. The second includes causes associated with single violations of the functionality of the stomach. As a rule, they are caused by one-time overeating, excessive alcohol consumption, and excessive smoking.

Reasons for admission

Among all the reasons why Rennie is appointed, the main ones can be distinguished:

  • increased acidity of the stomach and related diseases;
  • acute or chronic gastritis, including in the stage of relapse;
  • duodenitis;
  • ulcers of the stomach or duodenum, other manifestations of this area of ​​the digestive tract;
  • gastralgia, sour eructations;
  • heartburn, both single and recurring;
  • dyspepsia of all forms and manifestations;
  • heaviness in the stomach after overeating, impaired gastric secretion;
  • dyspepsia during pregnancy;
  • irritation of the gastric mucosa after drinking alcohol or smoking.

Dosage

With a single application, Rennie is consumed at the rate of no more than two tablets at a time. If the remedy does not work twenty to thirty minutes after taking, a second dose is allowed two to three hours after the first. The allowable dose for a healthy adult is sixteen tablets per day. However, taking more than three or four tablets per day is possible only under the obligatory supervision of a specialist. The same can be said about the use of funds by children under the age of twelve. According to the instructions, children of primary school age are forbidden to take Rennie, however, in some cases, it is possible to prescribe the drug by the attending physician in the absence of contraindications and allergic reactions to the composition of the drug.


Contraindications

Like any other drug, taking Rennie may be prohibited by the attending physician if there are certain grounds on the part of the patient, such as an individual reaction to the composition or the presence of chronic diseases. So, all the reasons why Rennie should not be used without fear for health and well-being can be classified into the main ones and those that relate to this drug. The first one can include:

  • individual rejection of certain components that are part of the Rennie tablets;
  • tendency to manifestations of allergic reactions to the salts contained in this preparation;

Reception of Rennie is also prohibited if the patient has:

  • there are violations in the functioning of the kidneys;
  • found an increased content of calcium in the body;
  • periodic or chronic increased muscle fatigue is diagnosed.

If there is any doubt as to whether Rennie can be taken by a particular patient, this issue is decided by the attending physician.

Possible Complications

In the entire history of the use of this drug among patients, there were practically no complications associated with the course of Rennie's treatment, not including situations with personal intolerance to individual components. However, sometimes there are cases associated with side effects from taking this anti-heartburn remedy. These include:

  • rashes like hives, edema, stool disorders;
  • a sharp increase in the level of secretion of gastric acid a few hours after an overdose of Rennie;
  • bloating, increased gas formation;
  • with violations of the functioning of the kidneys, a deterioration in the general condition is possible, which is confirmed by urine tests.

Moreover, it is worth recalling that despite the harmless characteristic, Rennie, like any drug, cannot be used uncontrollably and for a very long time. The lack of effect with prolonged use may indicate the presence of more serious diseases.

Reaction with other drugs

Rennie refers to drugs that do not tend to react strongly with other drugs, however, one way or another, tablets can affect the absorption of other drugs. In order to avoid unforeseen situations and plan treatment correctly, including with other drugs, you should carefully read the instructions for use before starting treatment with Rennie, and also consult a doctor if you have any doubts about compatibility with other drugs. When self-appointing Rennie, it should be borne in mind that:

  • this drug significantly enhances the therapeutic effect of aspirin, as well as drugs containing nalidixin acid;
  • Rennie's action can be significantly enhanced and continued when taken simultaneously with drugs such as Atropine, Scopolamine, Diphenhydramine.

Rennie himself can slow down the absorption from the gastrointestinal tract of drugs that contain iron elements, indomethacin, barbiturates, histamine blockers, beta-blockers, by reducing the secretion of the gastric mucosa and making absorption difficult. That is why such drugs should be used separately from Rennie with an interval of at least one hour.

Rennie during pregnancy and lactation

Since Rennie has established itself as a gentle drug that does not have serious side effects, experts most often prescribe it to women during pregnancy, as well as during breastfeeding. The following facts speak in favor of Rennie during pregnancy and lactation: Rennie does not increase edema in pregnant women; the drug does not help to fix the stool in a pregnant or nursing mother, but it may affect the child's stool; due to the content of calcium in the composition of Rennie tablets, it additionally saturates the mother's body with this element. However, despite the positive effect on the mother's condition, the appointment and instructions for the use of Rennie during pregnancy should be carried out under the strict supervision of a physician.

Rennie is a drug containing active ingredients that have an antacid effect. The drug quickly and for a long time neutralizes excess hydrochloric acid in gastric juice, protecting the surface shells of the organ. After taking the improvement of the condition is felt already within 5 minutes, since the drug has a high solubility. Relieves symptoms of increased acidity: burning behind the sternum, sour eructation, spasmolytic stomach pains, discomfort and heaviness, upset digestion. Relieves heartburn in pregnant women. Has good tolerance of components.

1. Pharmacological action

A drug that lowers the level of hydrochloric acid in the stomach.

The therapeutic effect of Rennie occurs 5 minutes after its application.

2. indications for use

Symptomatic treatment of conditions associated with increased acidity of gastric juice and inflammation of the esophageal mucosa due to the reverse flow of food.

3. How to use

  • Recommended dosage: 1-2 tablets of the drug when symptoms appear. In the absence of the desired result, it is possible to repeat the reception after 2 hours;
  • Maximum daily dose: 11 tablets.
Application Features:
  • The tablet should be chewed or kept in the mouth until completely resorbed;
  • High dose use may lead to the formation of kidney stones;
  • In the absence of positive results of treatment, patients should contact their doctor;
  • Mint flavored Rennie can be safely administered to diabetic patients.

4. Side effects

Hypersensitivity reactions to Rennie: angioedema, skin rashes,.

5. Contraindications

  • Functional insufficiency of the activity of the kidneys of severe degree;
  • Decreased concentration of phosphates in the blood plasma;
  • Hypersensitivity to Rennie or its components;
  • Age under 12 years old;
  • Individual intolerance to Rennie or its components;
  • Increased content of calcium ions in the blood;
  • Kidney calcification.

6. During pregnancy and lactation

The use of Rennie in the recommended dosage is possible at any stage of pregnancy and during lactation.

7. Interaction with other drugs

Simultaneous use of Rennie with:
  • other drugs can lead to a violation of their absorption;
  • thiazide diuretics should be accompanied by mandatory monitoring of the concentration of calcium in the blood.

8. Overdose

  • Digestive system: vomiting and nausea;
  • Musculoskeletal system: muscle weakness;
  • Cardiovascular system: an increased concentration of magnesium ions in the blood, a shift in blood pH to the alkaline side, an increased concentration of calcium ions in the blood.
All of these conditions occur in patients suffering from functional kidney failure, using Rennie at the maximum dosage for a long time.

If such symptoms appear, you should immediately stop taking Rennie and consult your doctor.

9. Release form

Chewable tablets with various flavors, 680 mg + 80 mg - 12, 24, 36, 48 or 96 pcs.

10. Storage conditions

Rennie should be stored in a dry, dark place out of the reach of children.
  • with menthol flavor - no more than five years;
  • with mint flavor - no more than three years;
  • with orange flavor - no more than three years.

11. Composition

1 tablet:

  • calcium carbonate - 680 mg;
  • magnesium hydroxycarbonate - 80 mg;
  • Excipients: sorbitol, pregelatinized corn starch, potato starch, talc, magnesium stearate, liquid paraffin, mint flavor, sodium saccharinate.

12. Terms of dispensing from pharmacies

The drug is released without a prescription.

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* Instructions for medical use for the drug Rennie published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST

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