Reduxin after how many days begins to act. Reduxin. Reviews of doctors. Side effects. What is called alimentary obesity and how can you calculate the body mass index

Desire to get rid of body fat problem areas pushes many people who are concerned about this issue to use special drugs that guarantee weight loss. One of the most commonly used drugs of domestic production is. This drug is sold in pharmacies strictly by prescription. This form of distribution indicates both the effectiveness of the drug and its serious contraindications.

This drug is quite dangerous drug. The fact is that Reduxin has a direct effect on the central nervous system. That's why this drug appoints only a specialist doctor after the examination of the patient, taking into account all indicators of health and possible contraindications. The action of Reduxin is based on the effect of appetite suppression. This function is performed by sibutramine, one of the main ingredients of this drug. AT modern pharmaceuticals this is the only substance that has an official approval for treatment overweight.

The drug has negative impact on the body in the presence of diseases such as anorexia nervosa, heart disease, tachycardia, ischemic disease, decompensated heart failure. A sufficient reason for refusing the use of Reduxin can be considered various mental illness. It is also sometimes seen hypersensitivity body to the ingredients that make up this product, in particular, to sibutramine.

The drug is also contraindicated in such a disease as Gilles de la Tourette's syndrome, or more simply, in the presence of generalized tics. It is not recommended to use this drug for weight loss with simultaneous reception antidepressants, neuroleptics, any drugs that increase blood pressure. A frivolous attitude in this case can lead to dangerous side effects.

Reduxin is not recommended for people suffering from dysfunction - thyrotoxicosis. If you want to use this drug as a means to adjust body weight, you should consider violations in the liver or kidneys. Before taking Reduxin, you need to necessary examinations at eye diseases, in particular, in the presence of a disease such as glaucoma.

Any minor abuse alcoholic drinks, drug dependence are also a sufficient contraindication to the use of this drug. In addition, it is not recommended to take Reduxin during pregnancy or lactation.

At permanent reception Reduksin weekly weight loss is 0.5 - 1 kilogram. Some may think that this is not enough. But it must be taken into account that sudden loss weight is the strongest stress for the body. Possible side effects include slight increase blood pressure, dry mouth, sometimes nausea. But such side effects are of short duration.

Therapeutic measures, including a complete change in lifestyle and lifestyle, daily routine, will significantly increase the effectiveness of the use this tool to reduce body weight. In the treatment of obesity, the main factor is the change in eating habits. This will be essential for future preservation. achieved result, when drug treatment will be finalized. Good luck reaching your goals!

Reduxin (Sibutramine + Microcrystalline Cellulose) is a drug for getting rid of excess body fat, realizing its therapeutic potential due to the combined action of its constituent components. Sibutramine becomes a true drug only after metabolic transformations in the biological environment of the body. Active metabolites of the drug - primary and secondary amines - inhibit the reuptake of neurotransmitters serotonin and norepinephrine. Increasing the concentration of the latter in synapses nerve endings activates serotonin 5-hydroxytryptamine receptors and adrenoreceptors, which, in turn, contributes to the development of a feeling of satiety, a decrease in the psychological need for food, and an increase in heat production. By stimulating beta-3-adrenergic receptors, sibutramine acts on adipose tissue (the so-called "brown fat"). A decrease in the proportion of adipose tissue in the body composition is accompanied by an increase in the level of lipoproteins high density(so-called " good cholesterol"") in the blood with a simultaneous decrease in the concentration of triglycerides, low density lipoproteins (" bad cholesterol»), total cholesterol and uric acid.

Being a pronounced enterosorbent, microcrystalline cellulose has good absorption capacity and detoxification properties. Absorbs and provides elimination from the body of various pathogens, exogenous and endogenous toxins, allergens, as well as potentially toxic metabolites.

After oral intake Reduxin is quickly and in a significant (about 80%) volume absorbed in the digestive tract.

It undergoes the effect of the first passage through the liver (it is at this stage that the active metabolites of the drug are formed). The half-life of sibutramine is about 1 hour, its active metabolites are 14-16 hours. The drug is excreted mainly by the kidneys. Multiplicity of reception of Reduksin - 1 time per day. The dose in each case is determined by the doctor, observing individual reaction the patient's body initial phase therapeutic course. As such a trial dose, 10 mg is used, with noted adverse reactions the dose for the drug is reduced by half, with confirmed individual intolerance - canceled. Optimal time reception - in the morning, after waking up, but if necessary, Reduxin can be taken with food at a later time. If in the first month drug therapy body weight decreased by less than 5%, then the dose is increased by 1.5 times (up to 15 mg). The duration of the therapeutic course in the absence positive results must not exceed 90 days. If, according to its results, a decrease in body weight by more than 5% was not achieved, the treatment is considered unsuccessful. The same conclusion follows in the event that the patient, after the initial weight loss, begins to gain weight again (3 or more kg). Total duration taking Reduxin should not exceed two years, since this drug is relatively young, and so far there has not been enough information about its efficacy and safety. When taking Reduxin, you must adhere to balanced diet and spend enough time exercising.

Pharmacology

Combined drug for the treatment of obesity, the action of which is due to its constituent components. Sibutramine is a prodrug and exerts its effect in vivo through metabolites (primary and secondary amines) that inhibit the reuptake of monoamines (mainly serotonin and norepinephrine). An increase in the content of neurotransmitters in the synapses increases the activity of central serotonin 5-HT receptors and adrenoreceptors, which contributes to an increase in satiety and a decrease in the need for food, as well as an increase in thermal production. Indirectly activating β 3 -adrenergic receptors, sibutramine acts on brown adipose tissue. Weight loss is accompanied by an increase in the concentration of HDL in the blood serum and a decrease in the amount of triglycerides, total cholesterol, LDL, and uric acid.

Sibutramine and its metabolites do not affect the release of monoamines, do not inhibit MAO; have no affinity for a large number neurotransmitter receptors, including serotonin (5-HT 1, 5-HT 1A, 5-HT 1B, 5-HT 2A, 5-HT 2C), adrenoreceptors (β 1, β 2, β 3, α 1, α 2), dopamine (D 1 , D 2), muscarinic, histamine (H 1), benzodiazepine and NMDA receptors.

Microcrystalline cellulose is an enterosorbent, has sorption properties and a nonspecific detoxification effect. It binds and removes from the body various microorganisms, their metabolic products, toxins of exogenous and endogenous nature, allergens, xenobiotics, as well as an excess of some metabolic products and metabolites responsible for the development of endogenous toxicosis.

Pharmacokinetics

Absorption, distribution, metabolism

After taking the drug inside, sibutramine is rapidly absorbed from the gastrointestinal tract, not less than 77%. It undergoes a "first pass" effect through the liver and is biotransformed with the participation of cytochrome P450 isoenzyme 3A4 to form two active metabolites (mono- and didesmethylsibutramine). After taking a single dose of 15 mg C max monodesmethylsibutramine is 4 ng / ml (3.2-4.8 ng / ml), didesmethylsibutramine - 6.4 ng / ml (5.6-7.2 ng / ml). C max sibutramine is reached after 1.2 hours, active metabolites - after 3-4 hours. Taking it simultaneously with food reduces C max of metabolites by 30% and increases the time it is reached by 3 hours without changing AUC. Rapidly distributed into tissues. The binding of sibutramine to plasma proteins is 97%, and mono- and didesmethylsibutramine is 94%. C ss of active metabolites in the blood is achieved within 4 days after the start of treatment and is approximately 2 times higher than the plasma level after taking a single dose.

breeding

T 1/2 sibutramine - 1.1 h, monodesmethylsibutramine - 14 h, didesmethylsibutramine - 16 h. Active metabolites undergo hydroxylation and conjugation to form inactive metabolites, which are excreted mainly by the kidneys.

Release form

Capsules №2 blue color; the contents of the capsules are white or white with a slightly yellowish tint powder.

Excipients: calcium stearate.

The composition of the capsule shell: titanium dioxide dye, azorubine dye, patent blue dye, gelatin.

10 pieces. - blister packs (aluminum/PVC) (3) - cardboard packs.
10 pieces. - cellular contour packings (aluminum/PVC) (6) - packs of cardboard.

Dosage

Reduksin ® is prescribed orally 1 time / day. The dose is set individually, depending on tolerability and clinical efficacy. The recommended initial dose is 10 mg, with poor tolerance, a dose of 5 mg can be taken. Capsules should be taken in the morning without chewing and drinking plenty of liquid. The drug can be taken on an empty stomach or combined with food intake.

If a weight loss of 5% or more is not achieved within 4 weeks from the start of treatment, then the dose is increased to 15 mg / day. The duration of therapy with Reduxin should not exceed 3 months in patients who do not respond well enough to therapy (i.e., who fail to reduce weight by 5% of the initial body weight within 3 months of treatment). Treatment should not be continued if, with further therapy (after achieved weight loss), the patient again gains 3 kg or more in body weight.

The total duration of therapy should not exceed 2 years, since there are no data on efficacy and safety for a longer period of taking sibutramine.

Therapy with Reduxin should be carried out by a doctor with practical experience in the treatment of obesity. The drug should be combined with diet and exercise.

Overdose

There are extremely limited data on overdose of sibutramine. In case of overdose, the patient should consult a doctor.

Symptoms: may increase the severity of side effects. Specific features overdoses are unknown.

Treatment: taking activated charcoal, gastric lavage, symptomatic therapy, with an increase in blood pressure and tachycardia - the appointment of beta-blockers. any special treatment and there are no specific antidotes. Needs to be done general activities: ensure free breathing, monitor the state of the cardiovascular system, and, if necessary, carry out supportive symptomatic therapy. The effectiveness of forced diuresis or hemodialysis has not been established.

Interaction

Inhibitors of microsomal oxidation, incl. inhibitors of cytochrome P450 isoenzyme 3A4 (including ketoconazole, erythromycin, cyclosporine) increase plasma concentrations of sibutramine metabolites with an increase in heart rate and a clinically insignificant increase in the QT interval. Rifampicin, macrolide antibiotics, phenytoin, carbamazepine, phenobarbital and dexamethasone can accelerate the metabolism of sibutramine. The simultaneous use of several drugs that increase the content of serotonin in the blood can lead to the development of a serious interaction. The so-called serotonin syndrome can develop in rare cases with the simultaneous use of Reduxin with selective inhibitors serotonin reuptake drugs (drugs used to treat depression), some migraine drugs (sumatriptan, dihydroergotamine), strong analgesics (pentazocine, pethidine, fentanyl), or antitussives (dextromethorphan). Sibutramine does not affect the effect of oral contraceptives.

With the simultaneous administration of sibutramine and ethanol, there was no increase in the negative effect of ethanol. However, the use of alcohol is absolutely not combined with the dietary measures recommended when taking sibutramine.

Side effects

Side effects, depending on the impact on organs and organ systems, are presented in the following order (often -> 10%, sometimes - 1-10%, rarely -< 1%).

From the CNS and peripheral nervous system: often - dry mouth, insomnia; sometimes - headache, dizziness, anxiety, paresthesia, and changes in taste; in isolated cases - back pain, depression, drowsiness, emotional lability, anxiety, irritability, nervousness, convulsions.

One patient with schizoaffective disorder thought to have existed prior to treatment developed acute psychosis after treatment.

Since the cardiovascular system: sometimes - tachycardia, palpitations, increased blood pressure, vasodilation. There is a moderate rise in blood pressure at rest by 1-3 mm Hg. and a moderate increase in heart rate of 3-7 beats per minute. In some cases, more pronounced increases in blood pressure and heart rate are not excluded. Clinically significant changes in the level of blood pressure and pulse are recorded mainly at the beginning of treatment (in the first 4-8 weeks).

From the side digestive system: often - loss of appetite, constipation; sometimes - nausea, exacerbation of hemorrhoids. With a tendency to constipation in the early days, it is necessary to control the evacuation function of the intestine. If constipation occurs, stop taking and take a laxative. In isolated cases, abdominal pain, a paradoxical increase in appetite, a transient increase in liver enzymes.

Dermatological reactions: sometimes - sweating; in isolated cases - skin itching, Shenlein-Genoch purpura (hemorrhages in the skin).

On the part of the body as a whole: in isolated cases, the following clinically significant adverse events are described: dysmenorrhea, edema, flu-like syndrome, thirst, rhinitis, acute interstitial nephritis, bleeding, thrombocytopenia.

Withdrawal reactions such as headache or increased appetite are rare. There is no evidence that after treatment there is withdrawal syndrome, withdrawal syndrome, or mood disturbances.

Most often, side effects occur at the beginning of treatment (in the first 4 weeks). Their severity and frequency weaken over time. Side effects are generally mild and reversible.

Indications

For weight loss with following states:

• alimentary obesity with a body mass index (BMI) of 30 kg/m 2 or more;
• alimentary obesity with a BMI of 27 kg / m 2 or more in combination with other risk factors due to overweight body ( diabetes Type 2 / insulin-independent / or dyslipoproteinemia).

Contraindications

• Availability organic causes obesity (eg, hypothyroidism);
• severe eating disorders (anorexia nervosa or bulimia nervosa);
• mental illness;
• Gilles de la Tourette syndrome (generalized tics);
• simultaneous reception of MAO inhibitors (for example, phentermine, fenfluramine, dexfenfluramine, ethylamphetamine, ephedrine) or their use within 2 weeks before the appointment of the drug Reduxin ® ; the use of other drugs acting on the central nervous system (for example, antidepressants, antipsychotics); drugs prescribed for sleep disorders containing tryptophan, as well as other drugs central action to reduce body weight;
• ischemic heart disease, decompensated chronic heart failure, birth defects heart disease, peripheral arterial occlusive disease, tachycardia, arrhythmias, cerebrovascular disease (stroke, transient disorders cerebral circulation);
• uncontrolled arterial hypertension(BP above 145/90 mm Hg);
• thyrotoxicosis;
• severe liver dysfunction;
• severe renal dysfunction;
• benign prostatic hyperplasia;
• pheochromocytoma;
• angle-closure glaucoma;
• established drug, drug or alcohol addiction;
• pregnancy;
• lactation (breastfeeding);
• children and adolescents up to 18 years of age;
• old age over 65;
• established hypersensitivity to sibutramine or to other components of the drug.

With caution, the drug should be prescribed under the following conditions: arrhythmias in history, chronic insufficiency blood circulation, coronary artery disease (including history), cholelithiasis, arterial hypertension (controlled and history), neurological disorders, including mental retardation and seizures (including history), abnormal liver function and / or kidney light and medium degree severity, motor and verbal tics in history.

Application features

Use during pregnancy and lactation

The drug should not be used during pregnancy due to the lack of a sufficiently convincing number of studies on the safety of the effects of sibutramine on the fetus.

Women childbearing age while taking Reduxin, contraceptives should be used.

Reduxin ® should not be used during breastfeeding.

Application for violations of liver function

Application for violations of kidney function

Use in children

Contraindicated in children and adolescence up to 18 years old.

special instructions

Reduksin ® should be used only in cases where all non-drug measures to reduce body weight are ineffective - if the weight loss within 3 months was less than 5 kg.

Treatment with Reduxin should be carried out within the framework of complex therapy for weight loss under the supervision of a physician with practical experience in the treatment of obesity.

Complex therapy for obesity includes both changes in diet and lifestyle, and an increase in physical activity. An important component therapy is to create the prerequisites for a stable change in eating habits and lifestyle, which are necessary to maintain the achieved weight loss even after drug therapy is discontinued. Patients need to change their lifestyle and habits as part of Reduxin ® therapy in such a way that, after completion of treatment, the achieved weight loss is maintained. Patients should clearly understand that failure to comply with these requirements will lead to a repeated increase in body weight and repeated visits to the attending physician.

In patients taking Reduxin ® , it is necessary to measure blood pressure and heart rate. In the first 2 months of treatment, these parameters should be monitored every 2 weeks, and then monthly. In patients with arterial hypertension (who have blood pressure levels above 145/90 mm Hg during antihypertensive therapy), this control should be carried out especially carefully and, if necessary, at shorter intervals. In patients in whom blood pressure twice exceeded the level of 145/90 mm Hg during repeated measurement. treatment with Reduxin ® should be suspended.

Particular attention should be paid to the simultaneous administration of drugs that increase the QT interval. These drugs include blockers of histamine H 1 receptors (astemizole, terfenadine); antiarrhythmic drugs that increase the QT interval (amiodarone, quinidine, flecainide, mexiletine, propafenone, sotalol); Gastrointestinal motility stimulants (cisapride, pimozide, sertindole and tricyclic antidepressants). Caution should be observed when using the drug against the background of conditions that are risk factors for an increase in the QT interval (hypokalemia, hypomagnesemia).

The interval between taking MAO inhibitors and Reduxin should be at least 2 weeks.

The relationship between taking Reduxin and the development of primary pulmonary hypertension has not been established, however, given the well-known risk of drugs in this group, with regular medical monitoring, it is necessary Special attention address symptoms such as progressive dyspnea (breathing disorder), pain in chest and swelling in the legs.

Influence on the ability to drive vehicles and control mechanisms

Taking the drug Reduxin ® may limit the patient's ability to drive vehicles and control mechanisms.

Being overweight makes a person feel uncomfortable. He wants to get rid of extra pounds. Reduxin tablets at a dosage of 15 mg should be used for weight loss, they will help you find a beautiful, slender figure.

What is the difference between Reduksin and Reduksin light?

Reduxin is indispensable for the treatment of obesity caused by diabetes, dyslipidemia and others. serious illnesses. The doctor must prescribe this drug.

Reduxin is sold strictly by prescription. The main active ingredient of the drug is sibutramine. It is actively used in complex treatment obesity. Thanks to sibutramine, a person experiences a feeling of fullness. Microcrystalline cellulose is present in the structure of the drug, it rapidly increases in size, swells in the stomach. Therefore, a person feels full for a long time and can be content with small portions of food. Unlike a drug with a similar name, Reduxin Light is simply a biological supplement.

It is easy to get in any pharmacy. Reduxin Light is available without a prescription. It is a capsule in the shell, they include gelatin, glycerin, citric acid.

Indications for use

The drug is used to treat obesity in such cases:

• The body mass index is 30 kg/m 2 and above.
• This figure reaches 27 kg / m 2 or more, but a person has other severe illness arising from obesity: type 2 diabetes mellitus, dyslipoproteinemia.

Contraindications

Patients with renal insufficiency can use this drug: it does not negative impact per person on dialysis. Reduxin cannot be used in case of individual susceptibility to its components. It should not be drunk if obesity is due to organic prerequisites (presence of hypothyroidism). The drug should not be used when serious violations psychological nature(with anorexia nervosa, bulimia).

Up to 2 weeks before start therapeutic treatment you need to refrain from taking phentermine, fenfluramine, drugs that adversely affect the state of the central nervous system. It is forbidden to drink it at the same time as strong sleeping pills that contain tryptophan.

The drug must not be used in severe pathologies heart: chronic heart failure, myocardial infarction. It is undesirable to use it with high blood pressure.

The drug is contraindicated during pregnancy, natural breastfeeding, tumors of the prostate, serious disorders of the kidneys. Reduxin provides for a certain age limit: it is not allowed to be used by people under 18 years of age. Persons who have completed 65 summer anniversary should also refrain from taking this remedy.

If a person suffering from a pharmaceutical or drug addiction, this medicine is prohibited.

Caution should be exercised when taking medication for arrhythmia, impaired blood supply to body cells, pathologies coronary artery. At nervous diseases, delay intellectual development, convulsive states you should not drink Reduxin. Caution should be exercised when using the drug by people with bleeding disorders.

Can I use the drug during pregnancy?

This medicine should not be drunk during pregnancy, since the effect of the medicine on the fetus has not been fully studied. Women reproductive age taking this medication should be carefully protected from unwanted pregnancy by using effective methods contraception. During breastfeeding, Reduxin cannot be taken, it quickly penetrates into mother's milk.

How is the dosage of the drug calculated?

The drug should be taken once a day. The dosage is selected taking into account individual characteristics patient. The recommended initial dose is 10 mg/day. If a person has poor tolerance components of the drug, you must use 5 mg of the drug per day. Reduxin is washed down with a large amount of liquid. It is allowed to take it on an empty stomach, if desired, you can drink the medicine at the same time as eating.

If after a month from the start of therapy, body weight has not decreased even by 2 kilograms, the dosage of the medication is increased to 15 mg per day. Treatment should be discontinued if for three months, the patient was not able to significantly lose weight (less than 5% of the initial body weight). Therapy does not need to be continued even in the case when a person successfully parted with extra pounds, but then they quickly return again. The duration of taking the medication does not exceed one year.

Diet and appropriate exercise must be followed while taking this drug.

What side effects occur when taking Reduxin?

Unwanted side effects usually disappear after a month of regular use of the drug. Over time, their severity becomes weaker. Often there are problems with sleep, there is a feeling of dryness in the mouth. The person may experience dizziness. In some cases, the patient feels anxiety and unreasonable anxiety.

Reduxin affects the work of the heart: a person develops symptoms of tachycardia, blood pressure rises.

The digestive organs are also subjected to a serious test: the patient often complains of poor appetite and nausea. There may also be problems with the intestines. When constipation occurs drug therapy should be stopped, the patient is prescribed drugs that have a laxative effect.

Reduxin causes a significant blow to the immune system. A person's resistance to the effects of harmful viruses decreases. When taking this medication, a person may develop a rash on the skin. In rare cases, Quincke's edema develops.

The drug slightly increases blood pressure, increases the pulse rate. Usually, these adverse events disappear on their own after a few weeks of using Reduxin.

A person may develop mental anomalies: psychosis, suicidal tendencies. In this case, the reception of Reduxin should be stopped.

Women who dream of beautiful and healthy hair should be careful while taking this drug. It can lead to alopecia.

Reduxin has a bad effect on the condition reproductive organs: it causes impotence, uterine bleeding.

What measures should be taken in case of drug overdose?

With an overdose of subutramine, a person develops tachycardia, headaches occur. In the case of taking a large dose of the drug, you must notify your doctor. A special antidote to eliminate the symptoms of an overdose has not been developed. It is necessary to wash the stomach, give a person Activated carbon, this will reduce the concentration in the body of the active substance. If the patient is suffering hypertension He is prescribed beta-blockers.

Significant Details

Reduxin does not combine well with macrolide antibiotics, phenobarbital. These medicines help accelerate the metabolism of sibutramine. The medicine for weight loss is not recommended to be used simultaneously with drugs containing serotonin. It is forbidden to combine the intake of Reduxin with the use of antitussives, which include ephedrine. The simultaneous use of the drug with drugs that affect platelet function is not allowed. In this case, the risk of bleeding increases.

When using the drug, you need to be careful when driving. Reduxin reduces concentration.

The drug well reduces excess weight, but it should be taken only after consultation with the doctor. Reduxin causes a lot of adverse side effects.

The pharmaceutical industry is constantly releasing new forms of drugs to reduce excess weight in outpatient settings without surgical intervention. One of these substances is drug reduksin instructions for use which is brought to your attention. There are two types of reduxin tablets. Main active substance- sibutramine hydrochloride. In the first version, reduxin tablets contain 10 mg of this substance. Second dosage of reduxin tablets contains 15 mg of sibutramine.

Tablets reduksin instructions for use recommends starting with a minimum dosage of 5 mg in the morning on an empty stomach. If within 30 days of treatment a five percent reduction in body weight is not achieved, then the dosage of reduxin is gradually increased. Before using reduxin tablets, reviews of doctors and patients are recommended to be carefully studied. Don't rely on independent methods obesity treatment. The drug reduxin can only be used as prescribed by a doctor and under close medical supervision. The drug reduxin has a large number of contraindications. Before you start taking reduxin, study the instructions for use with your doctor and consult if you have any contraindications to its use.

Reviews of doctors

The drug reduxin is used in medical practice for a long time already. This allows us to say that reduxin tablets have been studied enough and can be recommended by a doctor for use with a sufficient number of practical justifications.

Thanks to the extensive practice of using reduxin tablets, reviews of doctors and patients have been collected in enough. It cannot be said that these are only positive statements about medicinal properties drug. Basically, the drug reduxin reviews of doctors has the following:

• the active substance has a beneficial effect on weight loss, not in all forms of obesity;
• the drug reduxin is quite expensive, and its use is required for a year or a year and a half;
• reduxin diet pills cause a large number of side effects;
• reduxin tablets should not be used in adolescence and in pregnant women.

These are not all statements that contain reviews of doctors on reduxin. Exists great amount dissatisfied patients who were prescribed reduxin by mistake and led to side effects without visible weight loss.
The drug reduxin for weight loss acts at the neurohumoral level. The active substance reduxin blocks some receptors, due to which the patient has a quick feeling of fullness. This reduces appetite and eliminates the need for large amounts of food to fill up. In other words, the drug reduxin for weight loss acts as a means that limits appetite and prevents the possibility of overeating.

The second aspect is the cellulose included in reduxin. This substance is able to collect all the toxins and slags. Cellulose also contributes to a quick feeling of fullness, because. it fills the free space in the stomach.

Usually reduxin for weight loss acts slowly, with a gradually increasing effect. If you take reduxin correctly, then in the first month of treatment you will lose up to 10 percent of your original weight. In the future, the process of weight loss can be controlled.

Be careful! Do not take reduxin without a doctor's prescription.

Drug without a prescription in a pharmacy

Today, reduxin without a doctor's prescription can be bought at any Russian pharmacy. However, this should not be the deciding factor for you when choosing a drug for weight loss. The fact is that the drug reduxin acts positively only when:

• overeating and resulting obesity;
• complete absence of contraindications;
• no violation metabolic processes in the body.

If you have a metabolic disorder, or obesity is associated with hormonal disorders, then the drug reduxin is guaranteed not to help you. You'll still keep dialing overweight.

Should I take the drug myself

Anyone can buy reduxin without a doctor's prescription at a pharmacy on their own. But the consequences of this can be the most unpredictable. The fact is that the use of reduxin should take place under medical supervision. In particular, during treatment, you need to constantly measure blood pressure and pulse rate. The drug redu5xin causes an increase in blood pressure and increased heart rate. This adversely affects the well-being of a sick person. More long-term consequences the use of reduxin without the control of a doctor can be:

• anorexia;
• depression;
• decrease in working capacity;
• sleep disorders;
• mental disorders;
• various types of tics and spasms of smooth muscles;
• violation of reproductive function.

And that's not all dire consequences such a seemingly harmless act, how to decide to buy reduxin without a prescription and take it yourself

Practical use

Own practical use reduksin finds only at one form of obesity. It is associated with constant overeating. This is such a form when a person suffers increased appetite and cannot control it. It should be noted that this form of obesity is quite rare. In our country, the vast majority of women suffer hormonal forms obesity. With them, the use of reduxin is not only useless, but also dangerous for subsequent complications.

Instructions for use and contraindications

Pharmacological drug reduxin instructions for use recommends taking in the morning on an empty stomach. This allows the drug to be completely adsorbed into the blood and effectively begin to act throughout the ducks. Treatment should begin with 10 mg capsules. In the future, the dose of reduxin can be changed up or down.

For the drug reduxin, the instructions for use have a fairly large number of contraindications. In particular, the use of reduxin is prohibited in diseases such as:

• violation of the heart rhythm;
• anorexia;
• increased nervous excitability;
• hypertension;
• alcoholism and drug addiction;
• pregnancy;
• adolescence;
• diseases of the gastrointestinal tract;
• mental disorders;
• diabetes.

Contraindications to the use of reduxin include many other diseases and conditions. Also, contraindications include individual intolerance to individual components of the drug reduxin.

How diet pills work

Pharmacological pills reduxin for weight loss act simultaneously in two directions:

• sibutramine hydrochloride causes a feeling of fullness and partially destroys adipose tissue;
• microcrystalline cellulose fills the stomach, preventing the feeling of hunger from developing during the day.

The pharmacological action of the drug reduxin has been studied quite well.

How long can you take diet pills

Usually, doctors recommend taking reduxin for weight loss for 24 months. After that, the effectiveness of the drug is lost. Further use of reduxin becomes absolutely meaningless. Side effects may also occur. Although in the vast majority of cases, the side effects of reduxin develop in the first month from the start of treatment.

Today in the media here and there you can stumble upon information about the drug "Reduxin" (15 mg). Reviews of those who lose weight are very different: someone has lost a lot of weight, others have not lost a single kilogram. It must be remembered here that the first medicinal product, which is used to correct obesity when excess weight exceeds 30 kg. Doctors do not get tired of repeating that it should be used only as directed by a doctor. But women still do not listen to anyone and experiment with their health. Any nutritionist will confirm that the use of drugs for weight loss is already last resort despite the fact that this drug has passed all clinical researches and is considered quite safe.

Compound

What is included in the composition of the drug "Reduxin" (15 mg)? Reviews of those who lose weight say that when it is taken, there is mild condition euphoria, lack of hunger, high activity and other, somewhat strange sensations. At the same time, many point out intense thirst. What causes such changes? And what do these "magic" capsules contain? Perhaps, having become acquainted with the composition, you will change your mind about taking them. The main active ingredient is sibutramine. It is designed to reduce appetite, reduce hunger, so that a person who is used to overeating begins to consume fewer calories and, as a result, gradually lost weight. The second component is which allows you to provide a feeling of satiety. In a person prone to overeating, the stomach is very stretched, which means that you have to absorb a large amount of food in order for the receptors to work and give a signal of satiety. Cellulose swells greatly, absorbing a huge amount of water and, therefore, takes up space that was previously filled with food. All this ensures the high efficiency of the drug "Reduxin" (15 mg). Reviews of losing weight fully confirm the strong thirst.

What is sibutramine

If everything is clear with cellulose, then I would like to say a little more about sibutramine. According to the law, it refers to potent or poisonous substances that are prohibited from being used for the production medicines. But there is a loophole for the manufacturer, since no one controls its content in dietary supplements. You can easily buy a product called Lida, Beelight, Lindax, Reduxin, Flying Swallow tea and many other analogues that contain this substance. Subutramine, acting on noadrenaline and serotonin, reduces appetite and increases thermogenesis. This leads to the burning of already accumulated fat. A person feels a surge of energy and lack of hunger, and without diets, loses weight by 5-7 kg per month. But all organs and systems suffer from it. From the side of the central nervous system, insomnia, depression, anxiety are observed. The cardiovascular system responds with high blood pressure, tachycardia. In addition, liver function is impaired, nephritis is exacerbated, and this is only part of the consequences. This must be borne in mind by a person who decides to independently take the drug "Reduxin" (15 mg). Reviews of losing weight fully confirm the presence of such reactions, but the degree of their severity in each patient is different.

Instructions for use

According to the instructions, this drug should be taken once a day throughout the course. Its duration should be determined by the attending physician, as well as the dosage. The most potent is the drug "Reduxin" (15 mg). Reviews of those losing weight from 70 kg emphasize that it was this dosage that helped move the weight and speed up the metabolism. As body weight decreases, the dosage should be reduced so that at the end the drug is used only occasionally to maintain the result.

Since the state of health of everyone is different, the dosage that one person tolerates normally, others may cause discomfort. If discomfort occurs, the dose should be halved and seek the advice of your doctor.

Course duration

It depends on the initial weight and health status of the patient. Usually the duration of therapy does not exceed three months, especially if the drug "Reduxin" (15 mg) is prescribed. Reviews of those losing weight from 90 kg indicate that in exceptional cases the course is extended to 6 months, but the medication is taken under the strict supervision of a doctor. Once again, we draw your attention to the fact that the use of such potent pills is an extreme measure that is used when nothing helps. The same applies to all analogues of the drug, which we will talk about a little later.

Side effects

Especially often they appear when a person is prescribed a high dosage of the drug, namely "Reduxin" (15 mg). Reviews of those losing weight from 100 kg suggest that you have to endure some inconvenience so that the weight finally begins to decrease. Indeed, extra pounds begin to literally melt before our eyes, because there is absolutely no desire to eat. This is the only plus: it is rebuilt eating behavior person. During the course of treatment, he weaned to consume harmful products in large quantities. Accordingly, after the end of therapy, he continues to eat. healthy food, and indulges in delicacies only occasionally.

Worst of all, if a person independently “prescribes” this drug to himself. Incorrectly selected dosage threatens with serious violations of all organs and systems of the body. Most often, people note intense thirst and frequent dizziness, unmotivated outbursts of aggression, or, conversely, panic attacks. Very often people in the reviews complain about the strong headache along with insomnia. A few days of such a nightmare - and the thought of losing weight begins to recede out of fear for your health. Ends the sad list high blood pressure, tachycardia, total loss appetite, impaired coordination of movements.

Do not forget that 3-5 extra pounds is a reason to arrange yourself and go in for sports, and not drink serious drugs. It is the result of such an unjustified reception that mental disorders, anorexia, chronic constipation and the whole range of problems with internal organs.

"Reduxin-light"

After information about harmful effects the drug on the body has become publicly available, the demand for it has somewhat subsided. In addition, pharmacists have become stricter in asking for a prescription when selling a drug. In response, the manufacturer released "Ruduxin Light", which has nothing to do with its predecessor. It contains only vitamin E. It is this combination that guarantees the processing of carbohydrates into energy and blocks their storage in reserve. It is not necessary to start immediately with heavy artillery and take Reduxin (15 mg). Reviews of those losing weight from 75 kg talk about high efficiency absolutely safe dietary supplement. The only condition is that it is necessary to reduce the amount of calories coming from food, but at the same time provide a balanced diet in terms of proteins, vitamins and microelements. In addition, you need to do strength exercises daily.

Analogues "Reduksina"

There are many of them, and they all contain sibutramine in their composition. This is the well-known "Goldline", which can be purchased at the pharmacy without a prescription, which is a big omission. In addition to him, there are Lindax, Meridia, Slimia, Reductil and many others on sale. Dosage active substance in each of them is different, but the maximum allowable is contained in the drug "Reduxin" (15 mg). Reviews of those losing weight from 90 kg (photos of advertising brochures demonstrate a stunning effect, but let's not forget about the dangers to health) fully confirm that it is enough even for treatment advanced cases obesity. If you need to lose fewer kilograms, then the dosage is reduced. It is categorically not recommended to increase it, so if there are other numbers on the product you purchased, it is better not to risk your health.

Contraindications

First of all, it is arterial hypertension. It is forbidden to use the drug for people with diseases of the liver and kidneys. Sibutramine is metabolized in the liver and excreted through the kidneys. Any prohibit the use of the drug. During pregnancy and lactation, the intake is completely prohibited. It should not be used by children under 15 years of age. Do not forget that health is the most valuable thing you have.

Distribution and cost

The drug should be sold only through pharmacy chain. You should not risk your health and buy Chinese counterparts in Health Shops. Nobody checked these drugs for the percentage of sibutramine, so the reception can end very badly. Sale is carried out only by prescription, do not neglect the advice of a specialist if you decide to take the drug "Reduxin" (15 mg). Reviews say that it can not only become a very effective weapon in the fight against overweight but also seriously harm your health. The cost of the drug is quite affordable: a package containing 30 capsules of 15 mg each will cost you 1300 rubles.