How long should you take statins. Course treatment or permanent treatment with statins? Do I need to take statins

About 80% of cholesterol is formed by the liver and intestines, and does not come from food. Therefore, the main role in therapy aimed at lowering cholesterol is assigned to medicines. The statin group of drugs is the most popular in this treatment.

Relevance of statins

Statins lower blood cholesterol

Statins block the functioning of liver enzymes that are necessary for the liver to synthesize cholesterol. To maximize the effectiveness of drugs, a person taking statins should follow a special cholesterol-free diet. So that cholesterol from food does not negate the “effort” of these drugs.
Statins also have anti-inflammatory effects. Therefore, they stop local inflammation in the cholesterol atherosclerotic plaque in the lumen of the vessel, inhibiting atherogenesis.

What time of day is best to take statins? Are they related to food intake? How long to drink them?

1. Most cholesterol synthesis reactions are activated at night. Therefore, statins are recommended to be taken in the evening, a few hours before bedtime. Taking it in the morning minimizes the effectiveness of most statins.
2. You need to drink the drugs with plain water.
3. Do not use statins at the same time as grapefruit or its juice. Simultaneous intake of statins and grapefruit (or its juice) blocks the metabolism of the drug. Statins accumulate in the body, leading to overdose and side effects.
4. Eating foods high in animal fat also negates the effects of statins.
5. Interestingly, taking statins for a long time leads to a long-term reduction in cholesterol levels. Thus, a 5-year intake can lead to a decrease in blood cholesterol for 20 years.
6. During treatment with statins, it is recommended to regularly monitor cholesterol levels. First, after 1-3 months of taking the medication, then again after 1-2 months from the time of changing the dosage of statins. In the future, monitoring of blood cholesterol is carried out once a year, if there are no special individual indications.
7. You only need to take statins for a long period. Short-term use is not effective.
8. The combined use of warfarin with statins may potentiate the effect of the former and increase the risk of bleeding.

Most common statins

The main drugs of the statin group are as follows:

• Atorvastatin;
• Lovastatin;
• Pravastatin;
• Rosuvastatin;
• Simvastatin;
• fluvastatin;
• Cerivastatin.

Simvastatin

This drug is a prodrug. That is, in order to become an active substance, it needs to undergo a series of chemical transformations that occur to it when it enters the body. It has proven itself well, thanks to its ability to be quickly absorbed and have a therapeutic effect.

This drug shows its effect no earlier than a couple of weeks after the start of its administration. According to laboratory tests, small but obvious changes are observed only after a month or two.

hypocholesterolemic drug

Simvastatin leaves the body fairly quickly. After 12 hours, it in the body becomes less by 95%. Therefore, it is prescribed before the time of maximum cholesterol synthesis by the liver: at night. It is taken 1 tablet per day. There is no connection to food intake.

Lovastatin

This drug is also a prodrug. The effect of the treatment is manifested only after a couple of weeks of admission. It becomes maximum in a month and a half. Unlike simvastatin, this drug is absorbed slowly. It is absorbed especially slowly in the intestines if taken on an empty stomach. Its bioavailability is only 30%. After a couple of hours, its concentration is maximum. And in a day it is only 10% of the initial one.

Like others are static, it is taken once a day. You need to drink the drug during dinner. Therapy begins with a small dose, which is then gradually increased. Dose changes occur every couple of weeks. A large dosage (80 mg) can be divided into two doses (in the evening and in the morning).

Such high dosages are possible only with monotherapy with this drug. If anticholesterolemic therapy is carried out with nicotinic acid or fibrates at the same time, then the dosage of Lovastatin should not be more than 20 mg.

Crestor

The active ingredient in Crestor is rosuvastatin.

Taking this drug is somewhat different from treatment with other statins. It is equally effective if taken at any time of the day, and not just in the evenings, like the rest of this group.

By the time of the meal, it is also not tied in any way. But the requirements for adherence to an anti-cholesterol diet remain. As a rule, it is recommended to start taking Crestor with a minimum dose of 5 or 10 mg 1 time / day. After a month, the dose can be increased.
Often stop at 20 mg. Less commonly, with a high level of cholesterol in the blood, 40 mg of the drug is prescribed. Such doses are not recommended for those who have not previously treated cholesterolemia. When prescribing such dosages, lipid metabolism is monitored after 2-4 weeks.

Dosages and recommendations for the use of statins are individual in each case. Features of the appointment depend on the properties of each drug, laboratory parameters of the lipid profile, the patient's condition and the severity of atherosclerosis. Age, gender, comorbidities are also important. Great importance has the patient's readiness for long-term, and possibly lifelong use of drugs.

In recent years, much has been said about the dangers of high cholesterol at any age. As a rule, in the case of how to lower cholesterol, the doctor prescribes statins. These are drugs that can lower the level of this substance, but they affect the state of health in general. If this is possible, then first you need to try how realistic it is to normalize cholesterol in easier ways: physical activity, proper nutrition. Elevated cholesterol levels, if you do not try to improve your condition, can eventually lead to the development of atherosclerosis, a heart attack or stroke. All this is serious and you need to fight high cholesterol. To reduce its blood levels, special statins are prescribed, however, are these drugs always necessary?

Important! As a rule, statins are touted in the medical literature. However, you need to understand that these are pills that can harm the body in parallel, for example, if there are contraindications or while taking other medicines.

About the dangers of cholesterol

Even if it was possible to successfully use methods that can replace statins to lower cholesterol, this does not mean at all that it was possible to avoid the development of atherosclerosis and other problems. You need to understand that not all cholesterol is harmful. That is, the content of this substance in the blood is normal and necessary, but if it forms plaques, settling on the walls of blood vessels, this is already a danger. Especially if, against the background of this, lipid metabolism is disturbed, the density of complex compounds increases.

Uncontrolled intake of statins will definitely not help to qualitatively lower cholesterol, this approach will only harm health. But with an increased cholesterol rate, it is necessary to lower it, but you should not immediately rush to drink medicines, because there may be alternative solutions. As practice shows, often this problem can be solved simply by a balanced diet and proper diet.

Types of cholesterol:

1. Bad cholesterol is a substance that has a low density. It forms fatty protein complexes that tend to settle on the walls of blood vessels in the form of plaques. Only such cholesterol brings harm to the human body and the norm of its concentration in the blood is in the range of at least 4 mmol / l (or 160 mg / dl). When this indicator is disturbed and this was confirmed by tests, you need to review your diet and consult with your doctor if it is possible to postpone taking statins for a while.
2. Possible options is the presence good cholesterol in the blood, it is produced by the body itself and it resists the formation of plaques. Such cholesterol delivers dense compounds of fats to the liver, where they decompose and are excreted from the body. That is, the cause of atherosclerosis can also be not high bad cholesterol, but an insufficient amount of good cholesterol.

Doctors and scientists have been talking and arguing about the benefits and harms of this substance for a long time. For the first time, this issue has been closely studied since the seventies of the last century in Japan. It was then that Japanese scientists accidentally discovered the statin enzyme.

About statins

So, lowering cholesterol without artificial statins is possible, but here you still have to look for this enzyme not in the form of a medication. Medical statins are actively used today to lower blood cholesterol, they act at the cellular level. The liver synthesizes mevalonic acid, which is the first step in the formation of cholesterol.

The described enzyme directly affects this acid, suppresses the release of excess cholesterol into the blood plasma. As a result, the enzyme enters the vessels and arteries, interacts with cells there connective tissue at the intercellular level. As a result of such interaction, a reliable protective layer is formed inside the vessels, which resists the formation of blood clots, the development of the inflammatory process.

That is, a statin in its essence is a medicine both for the treatment and for the prevention of such serious and dangerous heart and vascular diseases as atherosclerosis, stroke or heart attack. Yes, this enzyme lowers cholesterol, but it can harm other organs and systems, especially in old age. So, you need to take medications with this enzyme only as prescribed by a doctor, and if possible, if the situation still allows, use natural statins to improve your condition.

About drugs and dietary supplements with statins

There is more than one drug that lowers the level of the substance in question with this enzyme. If the doctor prescribed, prescribed the dosage, then such a drug can be safely taken at home. But first, it may be better to try natural statins, which are not so dangerous for the body.

Synthetic drugs with the statin enzyme with the least side effects:

• The composition of the preparations "Simvastin", "Pravastin" and other similar products contains this enzyme, which is produced from mushrooms.
• In many other medicines, for example, Atoris, Roxera, a synthetic statin is added. That is, the enzyme is obtained during the synthesis of chemical elements, it is not natural, not natural.

Where to find natural statins

About how to replace synthetic statins, we will talk in this part of the material. First of all, if you slightly adjust your diet, in particular, take up the intake of fats, then the body will receive the necessary enzyme. All fats that enter the body interact with the liver and can be transformed by this organ into a different type of cholesterol.

Healthy fats, which will be transformed into good cholesterol, are always dietary. They are part of plant foods, these are almonds and other nuts, green tea and citrus vegetables. Blueberries and carrots, as well as garlic, will help to quickly lower cholesterol.

Important! Without medicine, you can normalize cholesterol levels if you include in your regular menu sea ​​fish, sea kale, some dry red wine, fresh juices. Avoid eggs, sugar and fatty meats.

The only effective way to feel the reducing effect of lowering cholesterol at home is to normalize nutrition. You need to constantly monitor your weight, lead an active lifestyle, give up smoking and excessive alcohol consumption. Additionally, in order to feel the reducing effect, on the advice of a doctor, you can drink some dietary supplements.

How long to take

If you can’t cope with how to lower cholesterol without statins, then medications selected and prescribed by a doctor strictly according to the results of tests and indications will have to be taken.

As a rule, courses of correctly selected drugs of this type are prescribed for 1-2 months, combined methods of treatment are used to prevent the body from getting used to and constantly motivate it to work better and better. The exact course of treatment and the regimen of taking drugs can only be prescribed by a doctor, be sure to take a blood test several times a year and know exactly your cholesterol level, indicating the state of the vessels as a whole.

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Do I need to take cholesterol pills: harm or benefit from taking statins? | Medprice

One of the most important organic compounds produced by our body is cholesterol. This hydrocarbon is necessary for almost all tissues. Without this compound, the normal existence of not a single living cell is possible. And most importantly, cholesterol is the main raw material for the production of sex hormones. Its deficiency leads to sexual dysfunction in men and amenorrhea in women.

But cholesterol molecules are heterogeneous, high-density cholesterol (good cholesterol) is useful and necessary. And molecules with low density (bad cholesterol) have an atherogenic effect, and become the main cause of such diseases as:

If elevated levels of bad cholesterol are found in blood tests, the doctor will definitely recommend a course of treatment with drugs that lower cholesterol and prevent the development of heart disease. vascular pathologies. The main groups of drugs for lowering cholesterol are fibrates and statins.

When prescribing statins, the doctor will definitely warn the patient that now this drug will become an integral part of his daily diet for life. And also that almost all drugs of this group have a lot of side effects. A person will have to decide on his own how to lower cholesterol. Take medication, and whether it is worth doing it, or change your usual lifestyle.

In addition to fibrates and statins, drugs containing fatty acids are prescribed, these are Omega 3 (fish oil) and lipoic acid. The decision whether or not to take statins should not be made on your own. This can only be done by a doctor. If in doubt, consult several doctors. This will help you find the right decision about how much the benefits of their action on your body will exceed the risk of unwanted pathologies.

Statins are cholesterol-lowering drugs

In pharmacology, statins are drugs whose main action is aimed at lowering the production of enzymes responsible for the production of cholesterol in the cells of the liver and adrenal glands. Instructions for the use of statins talk about such abilities of drugs as:

Possible side effects of taking statins

Regular use of statins during the treatment of high cholesterol often causes the development of side effects such as:

Quite often, patients taking statics complain of such types of ailments as:

• myalgia ( muscle pain),
• flatulence,
• abdominal (in the abdomen) pain,
• diarrhea, constipation,
• nausea to vomiting
• persistent headaches,
• state of chronic fatigue.

Violations by nervous system:

• amnesia (memory loss),
• general malaise,
• frequent dizziness,
• bouts of hypertension
• paresthesia (feeling of numbness, tingling and goosebumps),
• neuropathy of peripheral nerve endings (impaired conduction of limb impulses).

Gastrointestinal disorders:

• pancreatitis,
• cholestatic jaundice,
• anorexia (sudden, pathological weight loss),
• hepatitis,
• diarrhea,
• vomit.

Disorders in the musculoskeletal system:

• joint arthritis,
• myopathy (dystrophy of skeletal muscles),
• cramps in the calf muscles,
• acute back pain
• myositis (damage to the skeletal muscles of an inflammatory nature).

Immune system disorders (allergic manifestations):

• exudative erythema (allergic inflammation affecting the skin and mucous membranes),
• Lyell's syndrome (a severe form of allergic dermatitis, accompanied by a lesion internal organs),
• anaphylactic shock,
• hives,
• numerous skin rashes.

Disorders in the hematopoietic system:

• thrombocytopenia (a pathological decrease in platelet production).

Endocrine system disorders:

• type 1 diabetes mellitus,
• hypoglycemia (low blood sugar),
• obesity,
• limb edema,
• sexual dysfunction.

Absolute indications for taking statins as a means of prolonging life

The instruction issued for promotional purposes for cholesterol-lowering drugs of the statin group confidently convinces that these drugs effectively reduce the possibility of a heart attack or stroke, and also improve the quality of life.

In addition, it states that statins have almost no side effects and cannot harm the body, but are a wonderful way to prevent cardiovascular pathologies. The most common slogan of advertising companies is: "Take statin drugs constantly, and you will feel how the bad cholesterol goes away, and the good one increases its level." Under no circumstances should you unconditionally trust such advertising statements. Most of these peremptory claims are just advertising bait to buy expensive drugs.

In practice, the situation is much more complicated. For example, cholesterol-lowering statin pills are prescribed with great caution to the elderly. In general, the attitude of doctors to the use of statins today is quite controversial and ambiguous.

• According to some sources of special literature, taking statins is mandatory for all people with high cholesterol numbers - this is guaranteed to reduce the risk of developing cardiovascular pathologies.
• Other, no less competent scientific publications argue that, first of all, the ratio of possible harm to the intended benefit should be taken into account. And in older people, in the vast majority of cases, the potential harm far outweighs the therapeutic effect.

Standard methods for the treatment of cardiac pathologies include the inclusion of statin drugs in the therapeutic regimen. This increases the effectiveness of treatment and significantly reduces mortality. But practitioners believe that cholesterol pills, specifically statins, should not be given to every patient with hypertension or ischemic syndrome. And it is also impossible to prescribe statins to all elderly patients with high cholesterol levels without a preliminary examination.

Absolute indications for the appointment of statins are such conditions as:

• For prevention after a recent stroke or heart attack.
• During the preparatory period and postoperative recovery during reconstructive surgical interventions on the heart and central vessels. For example, setting up a grand stand for aneurysm abdominal aorta or coronary artery bypass grafting.
• Myocardial infarction or acute coronary syndrome.
• Severe coronary heart disease with an increased risk of heart attack or stroke.

Relative indications for prescribing statins, in which the benefits of taking them are very doubtful, are observed in patients with conditions such as:

• low risk of developing a heart attack;
• women before menopause;
• patients with a history of type 2 and type 1 diabetes mellitus.

In the retail pharmacy chain today, statins are represented by drugs of various cholesterol-lowering activities, these are:

• Lovastatin - lowers bad cholesterol up to 25%;
• Fluvastatin - lowers up to 29%;
• Simvastatin - up to 38%;
• Atorvastatin - up to 47;
• Rosuvastatin - up to 55%.

statin drugs

• Sincard
• Simlo
• Simgal
• Simvor
• Simvastol
• Simvastatin
• Simvacard
• Simvahexal
• Ovenkor
• Zokor
• Vasilip

• Tevastor
• Roxera
• Rosulip
• Rosucard
• Rosuvastatin
• Mertenil
• Crestor
• Akorta

• Liptonorm
• Tulip
• Torvacard
• Liprimar
• Atoris
• Atorvastatin Canon
• Atomax

Principles for choosing drugs

The decision to take drugs should be taken by a person independently, based on the recommendations and prescriptions of the attending physician. In the event that the patient agrees with the arguments of the specialist and is ready to constantly take medications, the choice of the appropriate drug, dosage and course of administration remains entirely with the doctor. The doctor bases his decision on the state of health of the patient, the presence and nature of chronic diseases, and also taking into account the individual tolerance of the body.

Self-administration and uncontrolled intake of cholesterol-lowering drugs is strictly prohibited. The fact is that instead of improving the condition, you can cause irreparable harm to yourself. In the event that, according to the results of the analyzes, there are any deviations in lipid metabolism or a significant deviation from normal indicators, you should immediately contact a cardiologist or therapist.

The doctor will assess the situation and the possible risk of side effects, taking into account indicators such as:

• the patient's weight in relation to height, his gender and age category;
• the presence of bad habits;
• existing chronic diseases of the heart or blood vessels, as well as pathologies of the liver and endocrine system.

After the appointment of a statin, it should be taken strictly in the recommended dosages and with constant control blood tests for biochemistry. In the event that the prescribed drug cannot be purchased due to the high cost, its substitute is negotiated with the attending physician. Practice shows that it is better to try to acquire original preparations. Generics entering Russian pharmacies are significantly inferior in quality and effect not only to originals, but also to imported generics.

When prescribing drugs from the statin group to elderly patients, the doctor takes into account the fact that the risk of developing myopathy doubles when taking these drugs together with drugs for diseases such as:

• gout,
• diabetes,
• hypertension.

The presence of a patient with chronic liver disease inclines the doctor to the choice of Ruvastatin preparations in reduced dosages. It is also possible to opt for drugs such as Pravaxol or Pravastatin. These medicines do not negative impact on the liver, but are absolutely incompatible with alcohol or antibiotics.

For patients with persistent muscle pain or an increased risk of muscle damage, Pravastatin is also prescribed. It not only has a gentle effect on the liver, but also has no toxicity against muscle tissue.

The presence of chronic kidney disease prohibits the appointment of Fluvastin - Leskol and Atorvastatin - Lipitor. These drugs are highly toxic to the kidneys.

In the case when it is necessary to reduce low molecular weight cholesterol, and there are no concomitant diseases, statins cannot cause harm. Therefore, the doctor may prescribe any drug in this group, for example, Ruvastatin or Atorvastatin.

Accurate data on the possibility of simultaneous use of statins and nicotinic acid is not yet available. Although there is evidence that nicotinic acid, together with statins, provokes a sharp drop in blood sugar, sudden gastrointestinal bleeding, exacerbation of gout and the development of myopathy.

Studies on the harms of statin side effects

Some time ago, treatment with statins for almost all cardiological diseases was practiced to lower cholesterol, while the harm of drugs was not fully understood. Statins were prescribed at all stages of ischemia, hypertension, and even at a low risk of developing cardiovascular pathology. This attitude was based on the recommendations of American scientists, who also advised the appointment increased concentration drugs, reaching up to 80 mg.

After the publication of the results of a study by the British medical journal, which showed that in 20% of cases, adverse symptoms appeared in patients treated with statins. And an independent commission confirmed these figures, the practice of prescribing statins was revised.

In fairness, it should be noted that in the territory Russian Federation There has not been a single independent study of the side effects of statins. And many cardiologists still actively prescribe statins, despite the risk of harming the health of patients with comorbidities. Similarly, in the United States, physicians frequently and frequently prescribe statins to lower cholesterol based on economic benefit, not health risk. In 2007 alone, the sale of statins brought in more than $40 billion in profits.

Latest Research Canadian scientists have shown that taking statins in patients increases the risk by 57% rapid development cataracts (symptoms, treatment), and if the patient also has diabetes, the risk rises to 82%. This means that older people with a history of diabetes are 5.6 times more likely to develop cataracts.

An analysis of 14 studies showed that statins do reduce the risk of developing cardiovascular disease, and specifically heart attack or stroke. But the presence of a huge number of side effects does not recommend prescribing these drugs to patients who do not have a history of cardiac pathologies and have never had a heart attack or stroke. It has also been noted that people who constantly take statins develop abnormal liver function, kidney failure, cataracts, and muscle myopathy. These patients also suffer from depression, mood swings, and short-term memory lapses.

Irrefutable facts about the importance of cholesterol in the life of the body and lowering its level with statins

German scientists, after a series of studies, came to the following conclusion: low cholesterol is much more dangerous for a person than high rates or statins, which, moreover, can lower cholesterol levels to critical indicators.

German specialists have proved that low cholesterol contributes to the development of such pathologies as:

• oncological tumors,
• liver disease,
• nervous diseases,
• strokes,
• anemia,
• suicidal tendency,
• premature death.

US scientists, after a series of studies, assert with all responsibility that: the development of heart attacks and strokes does not depend on cholesterol levels, but on a low content of magnesium in the blood serum. Its deficiency causes an increase in cholesterol levels, which leads to diseases such as:

• diabetes,
• hypertension,
• arrhythmia,
• angina.

A well-known scientific fact says that statins are able to suppress the main function of cholesterol - the restoration of damaged tissues.

All tissues of the body, and especially the vascular tissue, contain cholesterol molecules in large quantities. When the walls of blood vessels are damaged from the accumulation of proteins or under the action of amino acids, cholesterol cells immediately begin to eliminate this damage. In addition, for normal muscle growth and the vital activity of the body as a whole, low-molecular fat cells bad cholesterol. The lack of this element affects muscle pain, swelling and general weakness, up to the appearance of muscular dystrophy.

Is it good for the body to constantly reduce the amount of cholesterol?

Suppression of cholesterol production by statins is due to the inhibition of the production of mevalonate, a derivative of cholesterol. How does its deficiency affect the body? Mevalonate is not only a source of cholesterol production, it is necessary for the body to produce many more useful and important components that perform important functions. If this does not happen due to a lack of the original substance, many serious diseases develop.

Statins can contribute to the development of endocrine diseases, specifically diabetes, the manifestations of which contribute to an increase in bad cholesterol. Taking statins increases the risk of developing diabetes in patients with various pathologies from 10% to 79%. It has also been found that diabetics are 4 times more likely to develop various cardiac pathologies, such as:

• ischemic disease,
• stroke,
• heart failure,
• angina.

Statins lower the concentration of Glutamine 4 at the cellular level. This component is responsible for the quantitative content of glucose in the blood stream. More than 10,000 women over the age of 60 were surveyed in Britain. Two groups were identified. The first group of women took statins, the second did without them. The result showed that in the group taking statins, the risk of developing diabetes increased by 70%. Therefore, scientists concluded that the use of statins by women during menopause increases the possibility of developing diabetes by up to 70%.

The danger of side effects of statins lies in their slow development, almost imperceptible for a patient who has been taking these drugs for a long period. It was also found that statins affect the mental abilities of patients who take them for a long time.

The human body is a single coordinated system. The work of all organs is connected by physiological and biochemical factors. Constant interference with the process of natural functioning leads to completely unexpected results. By suppressing the enzymes of the cholesterol metabolic process, statins adversely affect the functioning of the liver. This can be expressed for obese people by a temporary improvement in the condition of the vessels. Or for patients with normal weight - the development of anorexia. And the constant forced adjustment of internal systems leads to more serious violations. In particular, mental insufficiency is noted in the elderly.

Many scientists have come to the conclusion that an increase in cholesterol levels cannot be considered the cause of the disease. It is rather an indicator of the presence of disorders in the digestive system and carbohydrate metabolism. High cholesterol is an indicator of the state of the body. It signals that work is underway to restore, and not destroy, internal organs. Moreover, the hypothesis of the influence of high cholesterol on the formation of atherosclerosis has not yet been confirmed.

In many developed countries, programs have been introduced to reduce the level of bad cholesterol, which included such areas as:

• adjustment of the diet;
• giving up alcohol and smoking;
• physical education and therapeutic exercises;

The results exceeded all expectations. During the period of this program, the death rate from heart disease in Europe and the United States decreased by 50%. Medical scientists thought, maybe maintaining a healthy lifestyle, avoiding alcohol and tobacco, switching to the consumption of products that help lower cholesterol, and regular exercise is a more effective and safe way to normalize cholesterol and prolong life. As opposed to the constant use of drugs that have serious side effects, the actions of which have not been fully studied.

fibrates to lower cholesterol

Another group of cholesterol-lowering drugs is fibrates. They are derivatives of fibric acid. These substances bind to bile and reduce the active production of cholesterol in liver cells. In addition, they reduce the content of lipids, which leads to a decrease in bad cholesterol.

Clinical studies have shown that fenofibrates can lower cholesterol by 25%, triglycerides by 45%, and increase high molecular weight cholesterol by up to 30%. Fenofibrates prevent the formation of extravascular deposits, reduce the amount of triglycerides and cholesterol in people suffering from hypercholesterolemia.

However, just like statins, they have just as many side effects. In most cases, manifested as digestive disorders:

• flatulence (bloating),
• dyspepsia,
• diarrhea,
• nausea and vomiting.

• Tycolor
• Lipantil
• Exlip
• Ciprofibrate
• Gemfibrozil

• Digestive system disorders:
  • pancreatitis,
  • hepatitis,
  • diarrhea,
  • formation of stones in gallbladder.
• Disorders in the musculoskeletal system:
  • muscle weakness,
  • myalgia,
  • myositis,
  • spasm of the leg muscles.
• Cardiovascular disorders:
  • pulmonary embolism,
  • venous thromboembolism.
• Allergic manifestations:
  • photophobia,
  • skin rashes,
  • itching and burning,
  • hives.

Other drugs to lower cholesterol

In uncomplicated cases or with a slight increase in cholesterol, it is recommended to take safer drugs. These can be dietary supplements that do not cause dangerous side effects, and help to slightly reduce the level of bad cholesterol. These are tools such as:

• Omega 3 (Doppelhertz),
• Omega forte Evalar;
• SitoPren (BAA),
• lipoic acid,
• Tykveol.

These drugs protect against cardiac disorders and vascular pathologies. And they are also an excellent prevention of depression and arthritis.

The article “Should I take cholesterol pills: harm or benefit from taking statins?” you can also read in Ukrainian: “Which is necessary to take pills for cholesterol: Skoda or measles for taking statins?”.

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Statins for cholesterol - the benefits and harms of cholesterol-lowering drugs

Medicines are used more often than others to treat diseases. For example, statins are used for cholesterol, and the benefits and harms of these drugs have been studied for a long time. What prevails? Cholesterol, or rather its excess, can cause many serious diseases. Should I use statins to reduce its amount in the blood? What are the side effects of these drugs and how best to take these drugs?

How do drugs work?

Human blood contains cholesterol. It is involved in the production of many hormones that are important for the body. Also, cholesterol helps the formation of vitamin D, without which human health can be greatly shaken. But all this is true if the amount of this substance does not exceed the norm. Once the rule is broken, cholesterol starts to do harm. Namely, it is the cause of the formation of fatty plaques in the blood vessels, which lead to heart attacks and other serious diseases.

If cholesterol has become high, it should be reduced immediately. For this you can use folk remedies or diet. But in some cases, it is necessary to start taking medications. For example, a doctor may prescribe a statin drug to lower cholesterol. And what is the principle of operation of such funds?

Statins work to lower cholesterol in the following way. Entering the patient's body, they inhibit the activity of certain enzymes. These substances are responsible for the production of cholesterol in the liver. As you know, almost 80 percent of cholesterol is “produced” by this organ. In addition, drugs from this group can help with the removal of LDL ("bad" cholesterol) from the body.

Medicines from the "statins" group have the following properties:

• firstly, they reduce the activity of enzymes that are responsible for the production of cholesterol by the liver;
• secondly, they help to reduce (by 60 percent or more) the level of "bad" cholesterol, or LDL;
• raise the level of "good" cholesterol, or HDL;
• do not have mutagenic and carcinogenic properties.

Due to the use of statins, the formation of fatty plaques in the blood vessels can significantly decrease or stop altogether. result such actions there is a decrease in the risk of manifestations of diseases such as ischemia and heart attack.

Any medications must be taken only as directed by a doctor, this also applies to the drugs under consideration, even if the patient has thoroughly understood what statins are and what is the principle of their effect on the body. Based on the actions of these substances, they should be taken at high cholesterol levels. But do not immediately run to the pharmacy. First of all, you need to familiarize yourself with the current practice of when and how statin drugs are used.

As a rule, cholesterol-lowering drugs from the statin group are prescribed in the following cases:

• if there is a high risk of heart attack or stroke during coronary disease;
• with myocardial infarction and acute coronary syndromes;
• after suffering a stroke or heart attack as a prophylactic;
• in the prevention and treatment of vascular atherosclerosis;
• after and before coronary artery bypass grafting and other operations on large vessels or on the heart of a reconstructive nature.

In current practice, drinking statins is most often recommended for any cardiological pathology. Due to this, in some cases, a significant reduction in mortality is observed. But specialists have not yet developed an unambiguous attitude to these drugs. For example, statins for cholesterol are almost never given to patients under the age of 45.

In addition, many doctors do not practice the use of such a medicine:

1. If the patient does not have serious diseases of the cardiovascular system, but simply there is an increased level of cholesterol in the blood. In this case, it is better to use a special diet in combination with exercise.
2. When the patient is out of the risk group.
3. If the client has a disease such as diabetes.
4. They try not to prescribe drugs from the “statins” group to patients before they have menopause.

It is worth noting that this group of drugs that lower cholesterol in the blood has been produced for a long time.

Therefore, experts distinguish between several generations of statins. The newer the drug, the more effective its action. For example, the very first statins had less of an ability to lower cholesterol, but they had many side effects. Fourth generation (today's last) generation drugs are able to reduce LDL and at the same time increase HDL. But still, a number of experts believe that they are dangerous to human health.

Side effects

Cholesterol pills from the statin group have been produced for a long time, so most of their side effects are well studied. Whether it is necessary to drink these medicines or not is up to the patients themselves in accordance with the recommendations from the attending physicians. But the patient taking statins should be familiar with all side effects in advance.

If you had to resort to these means, then you need to understand the following. Statins, or rather their main action, leads to a decrease in the production of the enzyme HMG-CoA reductase. It is this substance that is responsible for the production of HDL by the liver. But at the same time, cholesterol-lowering statins can reduce coenzyme Q10 levels. And what can this lead to?

Coenzyme Q10 is a substance vital to the body. It provides energy production in cells, especially in muscle tissue. As you know, the human heart is a muscle.

Here, the concentration of coenzyme Q10 is almost four times greater than in other tissues. human body. If this substance is not enough, then there will be little energy. And this means that the work of the heart can be disturbed. As a result, taking a statin can even be harmful to health. That is why it independent use, without the recommendations and supervision of a doctor, it is dangerous. In addition to possible problems with the work of the heart, these drugs have other side effects.

Among them, experts distinguish the following:

1. Pain and inflammation in the muscles. The patient experiences the same sensations as with the flu. In especially serious cases, the destruction of part of the muscle cells may begin. As a result of this process, myoglobin enters the blood, which harms the kidneys.
2. Impaired thinking and/or memory. The patient may not remember who he is and where he is for several minutes or even hours. This amnesia passes quickly.
3. Problems with the liver. Enzymes begin to accumulate in the blood this body. If after several tests a worsening of the situation is detected, then the drug should be stopped immediately.
4. A number of side effects that are characteristic of many medications. These, in particular, include nausea and vomiting, headaches and insomnia, flatulence and abdominal pain, and so on.

Many of these side effects do not appear immediately. Dangerous processes gradually accumulate and then can lead to serious complications.

Therefore, taking drugs from this group must be carried out under the strict supervision of a physician. In addition, you need to constantly take a blood test for biochemistry in order to notice possible negative consequences in time and stop taking the drug.

At what level of cholesterol and for how long to take statins - only a specialist should solve this problem.

Since drugs have a number of serious side effects, some of which can be dangerous to health, this decision should be balanced.

With the same indicators, taking the medicine is strictly not recommended if the patient has:

• kidney or thyroid disease;
• pathologies in the work of the endocrine system;
• if a woman is carrying a child, or even when planning this event soon. And also during breastfeeding of a newborn;

• individual intolerance and allergic reaction;
• in the presence of a cataract or an increased risk of its formation;
• serious disorders in the liver.

Since statins have a serious effect on the functioning of the liver, additional workload can significantly harm this organ. During treatment, it is strictly forbidden to drink alcoholic beverages. You also need to follow a certain diet that does not burden the liver.

Should You Take Statins?

Statins for cholesterol: the benefits and harms of these drugs. What more? Many patients have faced this issue. First you need to figure out which is better: when cholesterol is higher than normal, or vice versa - will it cause more harm? And how to take statins correctly, if you still take them.

With high cholesterol, you should not leave things to chance. As already noted, this substance can accumulate in the blood vessels in the form of fatty plaques. The body itself can find a solution to such a problem. Very often there is an expansion of the veins, or the blood is looking for other ways for its movement. But the fatty plaques themselves can be quite dangerous. If they come off, a blood clot forms, which can kill in a matter of hours. That is why the fight against excess cholesterol is an important task. But is it worth doing it with statins?

The fact is that the substances contained in the preparations help to reduce the production of mevalonate. This substance is a building material for a number of useful and important components, without which the work of many body functions is disrupted.

Studies have been carried out in a number of foreign countries. They identified important negative effects of taking these drugs. For example, a person taking statins was more at risk of developing diabetes.

The substances contained in the preparations help to reduce the level of glutamine 4. This compound works in the mechanism of controlling the amount of sugar in the blood. Such processes have a greater impact on patients over the age of 60 years. That is why both foreign and domestic medical institutions try not to prescribe statins to people from this risk group.

As you know, in patients with diabetes, the risk of such ailments as:

• ischemia;
• stroke and heart attack;
• angina;
• heart failure.

But it is precisely to combat these diseases that doctors recommend lowering the level of cholesterol in the blood.

Therefore, an increasing number of specialists are turning their attention to other methods of reducing LDL. For example, to reduce cholesterol levels, it is better to use complex treatment. It includes proper nutrition, exercise and the rejection of bad habits (smoking and alcohol).

It is worth noting that low blood cholesterol can be even more dangerous than exceeding the norm.

This substance is involved in many important processes for the body, and its lack can only do harm. For example, studies in Germany have shown that low cholesterol can lead to liver disease, nervous disorders, and even provoke the formation of cancer.

To normalize the situation, it is better to use a complex of diet and exercise.

There are many natural substances that help lower cholesterol levels:

• Ascorbic acid (rose hips, as well as hot and sweet peppers, sea buckthorn, and so on).
• Fatty acids (vegetable oils, oily fish).
• Policosanol (available in the form of capsules containing extracts from sugar cane).
• Resveratrol (red wine, grapes).

• Dietary fiber (bread with bran and cereals, as well as beans, carrots, and so on).

Of course, in some cases, which are listed in the previous chapters, the effect of taking statins will be higher than the risk of complications. Everything will depend on the opinion and knowledge of the attending physician.

It is he who must determine how to take statins, how long the treatment should last, and so on.

After all, many side effects dangerous to health occur gradually, without pronounced signs and manifestations. If the process of taking the drug takes place without proper control, the consequences can be very serious.

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Statins are cholesterol-lowering drugs

Statins are a group of medications that can significantly reduce the concentration of LDL-cholesterol (low-density lipoprotein or "bad" cholesterol) in the blood of a person. The mechanism of action of these drugs is as follows: drugs provoke a significant decrease in the production in the patient's body of special enzymes responsible for the production of cholesterol. Statins reduce the body's total production of cholesterol by 40-45%, thereby reducing the risk of heart attack, ischemia, and angina pectoris.

Side effects

Despite the undeniable health benefits, funds can cause many unpleasant side effects:

• sleep disorders;
• asthenia;
• constipation;
• diarrhea;
• migraine;
• nausea and vomiting;
• myalgia;
• abdominal pain;
• bloating;
• thrombocytopenia;
• neuropathy;
• dizziness;
• weakness;
• sudden weight loss, obesity;
• hepatitis and jaundice;
• pancreatitis;
• arthritis, myositis;
• joint pain;
• muscle cramps;
• rash and hives;
• erythrema;
• skin itching;
• impotence;
• puffiness;
• diabetes.

Who needs to take statins?

Absolute indications for taking drugs of the statin group are:

• hypercholesterolemia, insensitive to a radical change in diet and a diet lasting more than 3 months;
• high coronary risk associated with transient hypercholesterolemia;
• acute coronary syndrome;
• arterial hypertension;
• stroke, post-stroke condition with cardiosclerosis;
• atherosclerosis of the arteries;
• cardiosclerosis in the postinfarction state;
• operation performed on large arteries and vessels, on the heart.

Patients with diabetes and women in childbearing age it is not necessary to drink statins; before that, you need to consult a qualified specialist.

Contraindications

Do not take statins:

• during pregnancy;
• people with allergies;
• with lactation;
• with liver diseases (cirrhosis, hepatitis).

List of drugs for cholesterol

There are a great many drugs to reduce the concentration of cholesterol in the blood, below is an approximate list of the range of pharmacies.

Table 1: List of cholesterol remedies.

At what level of cholesterol in the blood can a doctor prescribe statins?

It is worth noting that the endless reduction of cholesterol is a road to nowhere. A person cannot live without it, this substance is present in the body in large quantities, it is a fuel and building material. There are two types of cholesterol: "bad" and "good". “Good” is just the same as the “fuel” of the body, the source of strength and energy. The human central nervous system cannot function without it. "Bad" cholesterol is different in that it has a high tendency to "stick" to the walls of blood vessels, creating "cholesterol plaques" - a direct path to atherosclerosis. It is worth getting rid of only the second type of cholesterol. You can find out its concentration by donating blood for analysis. It is better to do this in qualified clinics, where the accuracy of determining the concentration of fats in the blood will be maximum.

Cholesterol norms

Patients with cardiovascular disease need to periodically donate blood and check their cholesterol levels. normal value a value of 200 mg/dL is considered. However, few can boast of such a figure. Average in a woman 35 - 40 years old is 240 mg / dl. When cholesterol levels are between 250 and 280 mg/dl, it is recommended to reconsider the diet and start leading a healthy lifestyle. Nutrition recommendations for patients with high cholesterol (increase is not critical):

• reduce the consumption of butter, replacing it with vegetable (olive, vegetable, sunflower);
• replace fatty cheese, cottage cheese, sour cream and eggs ( egg yolk) on soy and its derivatives: this will help get rid of cholesterol and extra pounds;
• eat raw garlic: it contains enzymes that help to quickly digest and absorb animal fat;
• Do not eat lard, it is better to replace it with fatty varieties of fish;
• Grape juice (red grape varieties) is very beneficial for people with high levels of "bad" cholesterol.

If cholesterol is more than 280 mg/dL, you should consult a doctor for treatment (diet, exercise, medication, cholesterol monitoring). It is necessary to control the result of a new lifestyle for at least 4-5 months. To do this, you need to donate blood for re-analysis at least once every 30 days.

Risk factors

It is recommended to monitor the amount of cholesterol:

• men aged 40+;
• women after menopause;
• with diabetes;
• with hypertension;
• if the person smokes.

How to choose a statin?

To drink or not to drink a drug from the statin group is the individual choice of each person. However, it is worth knowing that once you start drinking these drugs, you will have to take them for life. Only the dosage of the medication, which the doctor prescribes after reading the results of a blood test, can change.

Self-administration of statins and their intake is unacceptable! The remedy must be chosen experienced doctor, guided by the condition of the patient, the testimony of his tests and the history of the disease.

The therapist or cardiologist has the right to prescribe the drug, taking into account age, gender, the presence of extra pounds, diabetes mellitus and heart disease. The selected drug should be drunk strictly according to the doctor's instructions, having previously discussed with him cheaper analogues that can be purchased at pharmacies.

Attention!

• The use of statins by older people who are already taking medications for hypertension or diabetes mellitus can lead to myopathy (cellular and muscular atrophy).
• Patients with hepatitis or cirrhosis can drink Rosuvastatin in small doses: the drug has the additional property of protecting liver cells. Taking antibacterial agents and alcohol at the same time as Rosuvastatin is unacceptable!


How to take valocordin drops

Statins - that's what they are called - will have to be taken for a fairly long period of time, and maybe constantly. Naturally, almost every patient will want to know as much as possible about this group of drugs.

What are statins?

These drugs include medications, the main function of which is to lower the level of low-density lipoprotein cholesterol (LDL). At first, elevated levels of this substance in the blood do not cause any negative symptoms. However, over time, without taking appropriate measures and medicines, the process of formation of atherosclerotic plaques will begin on the walls of blood vessels, which at one far from perfect moment will completely clog the lumen of the vessel, thereby provoking the development of a heart attack, stroke, up to death. Therefore, if the doctor decides that you need to start taking statins for cholesterol, most likely, the patient will have to follow the doctor's instructions.

Preparations of this type, according to a fairly large group of medical workers, are able to protect human vessels from serious damage, thereby significantly improving the quality of life. The results of serious studies have shown that statins practically do not cause side effects. A long course of use of these medicines can not only reduce the level of "bad" cholesterol, but also increase the amount of high-density lipoproteins - "good" cholesterol.

On the territory of the Russian Federation different names you can buy the following medicines to lower cholesterol: statins "Simvastatin", "Pravastatin", "Atorvastatin", "Fluvastatin" and "Lovastatin".

Effects of statins on the human body

There are no statistics on the frequency of use of drugs that reduce cholesterol in the blood in the territory of the Russian Federation. However, doctors in other countries use these drugs more often than any other. There are two opinions about the effect on the processes of cholesterol production.

One speaks of the unconditional benefits of statins as drugs that reduce the risk of blockage of blood vessels and the development of serious cardiovascular diseases (myocardial infarction, stroke, etc.).

Another opinion on this matter comes out with a statement about the harm that statin pills cause. In no case should you get rid of cholesterol for the simple reason that this substance is simply necessary for every cell in the body to restore in cases where cell membranes are damaged. Simply put, when for some reason the integrity of the walls of blood vessels and arteries is violated, the body uses cholesterol for “repair” work. By artificially reducing the content of this substance, we simply deprive our body of serious protection.

Of course, both of these opinions discussing statins for cholesterol have the right to life. The benefits and harms of using these drugs (if you read the special literature on this issue) take place.

What is normal cholesterol level?

It should be understood that cholesterol is not fat, but the alcohol that this fat holds. If such a substance binds to low-density lipoproteins (LDL), then “bad” cholesterol enters the vessels, and if it interacts with high-density lipoproteins (HDL), fat is carried out of the vessels (“good” cholesterol).

According to medical professionals, a cholesterol level of less than 200 mg/dl can be considered normal. But everything is far from clear. The HDL level in men should be at least 40 mg / dl, in women - 50 mg / dl. It should be noted that this figure should not exceed 130 mg / dl.

However, the question of what cholesterol is prescribed for statins may not be considered if the use of these drugs is vital. Doctors consider it mandatory to take funds if the patient has coronary artery disease, after suffering heart attacks or strokes, after surgical interventions on the vessels. In addition, according to a fairly large number of doctors, people with diabetes should definitely take statins for cholesterol, in which the risk of complications is potentially high.

"Natural" statins

If the doctor, for some reason, decided to prescribe medication statins, then, of course, it is unacceptable to cancel them on your own. However, after consulting with your doctor, you can increase your diet. mass fraction so-called "natural" statins.

For example, vitamin C (ascorbic acid) has the most beneficial effect on the functioning of the heart and blood vessels, inhibiting the production of LDL (low density lipoprotein) in the body. Cholesterol-lowering "statins" of this kind are present in many fruits and vegetables.

Further, meat and dairy products, cereals, green vegetables contain nacin (vitamin B3) - a wonderful natural statin. Ordinary garlic is also quite effective in helping to regulate cholesterol levels in the blood. Curcumin, a well-known seasoning, stimulates the liver to produce cholesterol and at the same time removes its excess from the body. Fish fat and flax-seed recommended for people suffering from heart disease.

It may well be that a certain group of patients will not need to take cholesterol-lowering medications. Statins natural origin and physical exercise can effectively deal with this problem.

Undesirable manifestations provoked by statins

In most cases, statins are well tolerated by the body. Doctors say it's better to take a pill as directed by a healthcare professional than to take an aspirin for a headache on its own. After all, pain can be the result of developing atherosclerosis (narrowing of the lumen in the vessel due to blockage by atherosclerotic plaques). In this case, the statin will remove the cause, and aspirin will only remove the consequences (and that is not a fact).

However, certain undesirable effects of statins on cholesterol can still be provoked. Quite often you can hear about headaches, nausea, abdominal pain, constipation, diarrhea. From the side of the central nervous system, dizziness, paresthesia, hypesthesia may appear. Also, patients often complain of joint pain, the appearance of myositis, muscle cramps, and back pain.

Of the allergic manifestations, they most often talk about itching, skin rash, and urticaria. Although in some cases there is a possibility of developing anaphylaxis. Sometimes manifestations of thrombocytopenia, obesity, impotence, peripheral edema are possible.

Basic rules for taking statins

In general, how to take statins for cholesterol should be indicated in the instructions for use. In addition, when making an appointment, the attending physician should sharpen the patient's attention to the treatment regimen. In addition to these two critical sources of information, people need to know that statins should not be taken with grapefruit juice. The substances contained in this product prevent their destruction and excretion from the body, as a result of which the concentration of the latter in the blood increases. This situation can provoke destructive processes in muscle fibers, the development of liver failure (and this is a life-threatening condition).

In addition, it is advisable to take statins not in the morning, but in the evening one and a half to two hours before bedtime.

If we talk about the duration of the course of treatment with these drugs, there is no such thing at all. Statins for cholesterol in most cases need to be taken for life. It is only permissible to vary the dosage.

How to choose statins?

All currently used drugs have a high level of effectiveness. However, statins for new generation cholesterol are in the greatest demand. Most often, medical workers distinguish Atorvastatin from a number of medicines.

The most significant plus of this tool is a large evidence base. For this medicinal product, the largest number research. It is easiest and easiest to apply once a day. There is a pronounced dose-dependent effect, which some statins do not have at all. Also, Rosuvastatin is a new generation of drugs. A feature of these two medicines is the ability to quickly and painlessly lower cholesterol levels in patients.

Health professionals have several principles for choosing a statin for each individual patient, depending on the history and health status. Any drug can be used to lower LDL. For those who suffer from chronic liver disease, it is better to prescribe Pravastatin or Rosuvastatin in low doses. With muscle pain, preference is given to "Pravastatin", as a drug that has a minimal toxic effect on the muscles. Patients with diseased kidneys are not prescribed Atorvastatin and Fluvastatin.

Opinion "against" the use of statins

Once in the human body, statins with high cholesterol reduce its level in the blood, thereby inhibiting the production of mevalonate (a cholesterol precursor). Thus, the sequence is clear: less mevalonate - less cholesterol. At first glance, nothing wrong. However, mevalonate is a source not only for cholesterol, but also for a number of substances that carry important functions. The loss of these substances from the biological cycle can lead to a lot of health problems.

The use of cholesterol to repair damaged tissues and blood vessels was discussed earlier. And the fact that in the event of a crisis (need "repair" cell membranes, vascular walls, etc.) cholesterol synthesis increases in the body, looks natural. Satisfies the increased needs of the liver, its resources are sufficient to increase the production of cholesterol by 400%.

It is clear that looking at things from this point of view radically changes people's opinion about the need to reduce the level of this substance. So is it worth taking permanent basis statins for cholesterol? According to doctors and most consumers, artificially lowering cholesterol levels with the help of synthetic drugs can provoke the development of a number of complex diseases. Violation of the functioning of the adrenal glands (the first link in the chain of deviations) may well lead to an increase in blood glucose, brain damage, a lack of minerals, asthma, and also cause a weakening of libido, infertility, inflammation and edema, and abnormalities in the functioning of the reproductive system.

Who needs to take statins?

Currently, any lipid-lowering drug (statins from cholesterol among them) is undergoing an ambiguous attitude towards itself. As a result of some studies, it is postulated that regularly lowering cholesterol levels through the use of such drugs reduces the risk of developing problems in the cardiovascular system. Other studies lead scientists to conclude that the number of side effects is not comparable to the benefits of these medications.

Today, in Russia, statins are included in standard scheme treatment of many pathologies of a cardiological orientation. Their use reduces the mortality rate of the population. However, this does not mean at all that these medications should be prescribed to every patient with arterial hypertension or coronary artery disease. Also, statins are not prescribed to people over the age of 45, and to those who have slightly elevated blood cholesterol levels.

At the same time, according to health workers, these drugs are simply necessary for those who have had a heart attack or stroke (for secondary prevention). They are also recommended for patients who are scheduled for reconstructive operations on the heart and large vessels (coronary bypass grafting). The reason for starting statins is the state of acute coronary syndrome, ischemia with high risks of stroke or heart attack.

From the foregoing, it follows that for patients with severe vascular lesions, statin medications are an opportunity to prolong life.

Statins - a breakthrough in medicine or not?

Proponents of evidence-based medicine can sleep peacefully. Clinical studies on the effectiveness of statin medications have proven that these lipid-lowering drugs are indeed effective in lowering blood cholesterol levels and, as a result, reduce the risk of developing cardiovascular pathologies. In addition, some new generation statins can even affect the size of atherosclerotic plaques (Rozuvastatin has just such an effect). And this is an absolute plus for such drugs.

However, one cannot be completely sure that statins bring only benefits. Cholesterol is required by the body for many biological processes. They are very important for the normal life of every person. A lot of negative consequences can be provoked by constantly taking statins for cholesterol. Benefit and harm practically go hand in hand.

Under big question the safety of the use of these drugs by patients age group from 50 to 60 years old. At first, the results of the studies were so impressive that the approval for the use of statins was issued 2 years ahead of schedule. This did not make it possible to assess the side effects that occur with long-term use. Up to 98% of people taking statins for a long period complain of rather severe muscle pain, increased fatigue, speech impairment and problems with the vestibular apparatus. There are cases of cognitive dysfunction and fine motor skills of the hands.

There are situations when statin drugs are vital for patients. And sometimes you can get by with a balanced diet and exercise.

The right to decide whether to take lipid-lowering drugs or not belongs to the attending doctor, who can assess the state of health of his patient as a whole and take into account all the nuances and related problems.

Benefits and harms of treating high cholesterol with statins

The question of normalizing cholesterol levels in modern life is extremely acute. Many doctors are sure that all means are good in solving the problem.

Statins for cholesterol, the benefits and harms of which are widely discussed, are prescribed quite often. At the same time, the guarantees of their complete safety are rather unsteady, since almost every drug has its own contraindications and side effects. Not only the components of the drug, but also self-medication and excess dosage can provoke their manifestation.

Mechanism of action of statins

Statins are medications that lower cholesterol levels in the blood. They do not affect cholesterol as such - they do not destroy and do not remove from the body. The drugs interact with the liver, inhibiting the secretion of an enzyme that is involved in the production of cholesterol.

AT human body contains lipoproteins with different density - low and high. These are carriers of cholesterol from the liver to body tissues and vice versa. With proper metabolic processes, they are harmless to health. But “bad” cholesterol can cluster and form plaques that lead to severe pathologies.

Statins help to reduce the number of cholesterol transporters to tissues. Conversely, the concentration of cholesterol carriers from tissues to the liver increases. That is, the direct and reverse transport of cholesterol is normalized. In this case, its overall level decreases.

At the same time, drugs are broken down adipose tissue into separate fragments, struggling with hereditary prerequisites for elevated cholesterol concentrations. This property is unique to statins.

Indications for the use of drugs

Treatment with statins is prescribed:

• When the cholesterol content in the blood is over 5.8 mmol / l - if it cannot be corrected with a diet for three months or more;
• With atherosclerosis and heart pathologies - to prevent further development;
• In diseases that provoke the appearance of atherosclerosis;
• For prevention to young people - if one of the family members suffers from hereditary heart diseases;
• As a preventive measure for the prevention of atherosclerosis for people of mature age - with the aging of the body, the risks of developing pathology increase.

The use of statins is contraindicated:

• If the risk of developing diseases of the heart and blood vessels is low;
• Women before menopause;
• Patients suffering from diabetes;
• Children and patients over 75 years of age - the likelihood of side effects increases due to poor tolerance of the drug, the harm from statins will be more than good.

On the question of at what cholesterol levels you need to take statins, doctors disagree. But after heart attacks, rehabilitation measures in without fail provide for the use of these drugs.

Very rarely they are allowed to be taken by children with genetic disorders and an excessively high concentration of "bad" cholesterol in the blood. Statins in these circumstances are prescribed, carefully weighing the benefits and harms that they can bring. But under any circumstances, the doctor needs to correctly calculate the dosages and regimens for taking drugs - for each patient individually.

Benefits of using statins

In certain situations, statins for cholesterol bring tangible benefits. Sometimes they become the patient's only chance to save a life.

• Help the body fight atherosclerosis;
• Promote rehabilitation after strokes and heart attacks;
• Prolong the life of a patient suffering from serious illnesses;
• Reduce the content of "bad" cholesterol in the blood;
• Prevent pathologies of blood vessels and heart.

Many patients respond well to statin therapy. But the need for their long-term intake (about three to four years) negatively affects the body's immune system.

Harm caused by drugs

The patient is sometimes unaware of the dangers of statins. The harm from their use does not appear immediately. Therefore, with long-term use of drugs, it is necessary to monitor the state of health - regularly take appropriate tests and visit the attending physician.

The disadvantages of long-term use of statins are manifested by the reaction:

• Nervous system - agitation, unexplained mood swings, insomnia, dizziness, weakness,
• Non-inflammatory nerve lesions;
• Digestive systems - constipation, diarrhea, flatulence, poor appetite, vomiting, anorexia, drug jaundice, pancreatitis;
• Locomotor system - severe joint and muscle pain, pain in the back, aching bones, cramps, exacerbation of arthritis;
• Circulatory systems - a decrease in the concentration of platelets in the peripheral circulatory system.

Cholesterol statins can disrupt metabolism, causing sudden changes in blood sugar levels. allergic reactions may be accompanied by itching, rash, runny nose, peeling of the upper layer skin, anaphylactic shock.

Sometimes taking statins is harmful to the body, provoking the development of respiratory diseases, causes impotence, obesity, edema, and very rarely Alzheimer's disease. There have been cases of renal pathologies, manifestations of cataracts, vascular thrombosis, eczema.

The risk of side effects increases with the age of the patient. An inadequate response to drugs may occur in people of a slender physique and in alcoholics - statins and alcohol are incompatible. For patients with pathologies of the musculoskeletal system, drugs are indicated in cases of emergency and under medical supervision.

It is not recommended to use statins simultaneously with certain drugs (antibiotics, antidepressants, verapamil, fluconazole, erythromycin). It is necessary to refuse the use of grapefruits and juices based on them.

Several generations of drugs

The group of statins is represented by drugs of several generations.

statin group drugs

The drugs differ in active substance, otherwise they are all similar. Statins of the latest generation - drugs of the Rosuvastatin group; its name is identical to the name of the main active agent, the benefits and harms of taking are individual for each patient.

natural statins

Statins have a number of serious contraindications, which is why many suspicious patients are afraid to use them.

But there is a natural replacement - the well-known "anti-cholesterol" substances:

• Ascorbic acid (citrus fruits, sea buckthorn and blackcurrant berries, rose hips, sweet peppers, cabbage);
• Nicotinic acid (nuts, all types of meat and red fish);
• Omega-3 fatty acids (all types of red fish, vegetable oils);
• Policosanol (extracted from sugar cane, sold in pharmacies);
• Pectin (apples, carrots, cabbage, beans and cereals, bran);
• Resveratrol (red wine, grape skins);
• Curcumin (turmeric).

Soy products and ordinary garlic contribute well to lowering the concentration of cholesterol in the blood.

Features of the use of drugs

When assessing the harm, the patient may refuse to use drugs that are dangerous, in his opinion. But the decision to take or not to take statins should be made after careful consideration of the risks involved. Including those that occur without treatment with these drugs.

It is important to know the features of the use of statins:

• Their reception sometimes becomes lifelong. Without them, the patient may feel a significant deterioration in health - at times compared to the initial state.
• Only a specialist can determine the drugs suitable for the patient - taking into account all chronic diseases. Independent appointments are strictly prohibited.
• achieve effective result with the safe use of drugs, it is possible, observing the dosage correctly chosen by the doctor.
• When prescribing medications, the doctor determines the necessary frequency of biochemical blood tests; the patient must strictly comply with it.
• With pathological changes in the liver in small doses, it is recommended to take Rosuvastatins. They will cause the least harm to the diseased organ. During therapy, nutrition should be carefully monitored. Alcohol and antibiotics must be completely eliminated.
• Patients with kidney disease Fluvastatins and Atorvastatins are not recommended. Their impact is most toxic to the kidneys.
• If the prescribed drug is not affordable, the possibility of its replacement must be discussed with the attending physician.
• Statins are almost incompatible with other drugs. When taking several drugs, complications and side effects may occur.

According to pharmaceutical companies and representatives official medicine The benefits of statins far outweigh their harms. But the opinion of independent researchers is different - the side effects of drugs are much more dangerous than their benefits. Probably, as in most cases, it is important to find a middle ground.

It is clear that taking statins brings both harm and benefit to the patient. Therefore, you can take them only as prescribed by a doctor. It is he who will determine the optimal type of drug for the patient and its dosage. And to listen to the doctor's recommendations or not is the patient's business.

Feedback on the effectiveness of statins

Reviews of patients taking statins for cholesterol equally testify to the benefits and harms of drugs. They allow us to conclude: in the fight against "bad" cholesterol, drugs are very effective. But the side effects sometimes make this struggle unbearable.

The specifics of taking statins from cholesterol, the possible benefits and harms of taking them

In many cases, statins are prescribed after a cholesterol test. The main task of these tablets is to prevent the development of diseases of the heart and blood vessels.

The doctor is obliged to explain to the patient that now he needs to take statins every day. But, like any cholesterol-lowering drug, statins have both positive and negative effects.

What are statins?

Statins are chemicals that regulate the production of enzymes that synthesize cholesterol in the human body.

How statins work:

1. Lowering the concentration of LDL in the blood by inhibiting HMG-CoA reductase and stopping the synthesizing processes of cholesterol in the liver.
2. Decrease in LDL levels in people who have been diagnosed with homozygous familial hypercholesterolemia, which is not treatable with other medications.
3. Lowering the amount of cholesterol by a percentage, LDL - by a percentage.
4. An increase in the concentration of high density lipoproteins.
5. Reducing the risk of developing ischemic pathologies by a percentage, myocardial and angina pectoris - by a percentage.
6. Absence of mutagenic and carcinogenic effects on the body.

What are the indications for statins?

At what levels of cholesterol are statins effective? Prescribing medications is advisable in such cases:

• Hypercholesterolemia. Exceeding the norm of cholesterol does not decrease for several months.
• Pronounced clinical atherosclerosis.

• Diagnosed cardiac ischemia.

Scientists still have not given an answer at what level of cholesterol statins - the best medicines for treatment. American scientists, after conducting a series of studies, argue that statins can be used to lower cholesterol when the norm is exceeded by 3.5 mmol / l. This is especially rational if the patient meets one of the criteria:

• Over 58 years old.
• Male gender.
• Suffering from obesity.
• genetic predisposition.
• Hypertension.
• Has diabetes.

Benefits of statins

Statins for the treatment of patients have a number of undeniable advantages:

1. Reduce the rate of deaths from heart disease by 39 percent over the first 5 years.
2. Reduce the risk of heart attack and stroke by 33 percent.
3. Effective. Systematic use lowers the level of LDL by a percentage, increases the amount of HDL by 25 percent.
4. Wide selection of analogues. The pharmaceutical market provides a wide range of statin drugs, which allows you to choose statins for financial opportunities.

Side effects

Despite the fact that cholesterol-lowering drugs are effective and well tolerated, their use does not go unnoticed for health. This shortcoming is due to the fact that in order to therapeutic effect statins should be taken for a long time, from 3 to 4 years.

Muscles suffer the most from statins. A patient who uses drugs may develop myopathy over time, the main symptoms of which are weakness and soreness of the skeletal muscles. If, after the manifestation of the disease, you do not stop drinking the pills, rhabdomyolysis will appear - muscle breakdown, due to which the renal tubules are blocked by decay products, acute renal failure develops.

Often there are problems with memory and thinking. The patient has memory lapses for several hours, in which he cannot remember himself and his close environment.

The risk of side effects increases if, in parallel with taking statins, a person uses such medications:

Also, the likelihood of side effects is affected by:

• Age of the patient (in the elderly it is observed 55 percent more often than in patients under 48 years of age).
• Diseases of a chronic nature.
• Wrong nutrition.
• Experienced surgical interventions.
• Improper functioning of the liver.
• Excessive consumption of alcoholic beverages.
• The use of a large number of tablets.
• Drinking freshly squeezed grapefruit juice.

Taking statins with high cholesterol provokes increased activity of transaminase, a kidney enzyme, which signals the harm that the drug does to the liver. Especially - the situation is aggravated if the patient systematically takes alcohol.

Often after taking statins, patients complain of the manifestation of such conditions in the morning:

1. Headache.
2. Rash and redness on the skin.
3. Insomnia.
4. Disorders of the gastrointestinal tract.
5. Flatulence.
6. Lack of appetite.
7. General malaise.
8. Drowsiness.
9. Vomiting.

These symptoms appear less frequently, and in some people completely disappear if the doctor allows you to lower the dose of the medicine.

Therefore, it is better to take statins under the supervision of your doctor and at least once every few months to take tests to check your health. Such studies include:

• Test for alanine aminotransferase levels.
• Check for the amount of aspartate aminotransferase in the blood plasma.
• Determining the amount of cholesterol.
• Determination of the level of creatine phosphokinase.

List of drugs for lowering cholesterol in the blood

We bring to your attention a list of statins and their effectiveness in lowering cholesterol.

Classification of statins

So far, there are four generations of statins. At the heart of the representatives of the first - lovastatin and simvastatin - penicillin fungi. Representatives of other categories are bred under synthetic conditions.

It is a mistake to think that first-generation statins have fewer side effects than more modern ones. All who took simvastatin complained of symptoms characteristic of the latest generation of statins.

How to choose the right statins

Whether it is necessary to take statins is a personal choice of each, which he must make after consulting with a specialist. If it is decided that medications should be taken, the selection of the drug is carried out by the doctor, who must take into account the individual characteristics of the patient.

If lipid metabolism is disturbed, and a blood test showed abnormalities, it is necessary to visit a cardiologist. The doctor will select the right statin based on the characteristics of the patient:

1. Age category.
2. Addiction to bad habits.
3. Presence of CVD and diabetes.

If the decision is made to take a statin to increase HDL levels, then this should be done according to the instructions prescribed by the doctor. He will also appoint a schedule for the delivery of blood biochemistry, which will help control the benefits and harms of statins from cholesterol. Implementation of this recommendation is mandatory.

If the prescribed statin is too expensive for the patient, he should immediately tell about it and choose a cheaper medicine with the doctor. The main thing is that it was an original drug.

Principles of prescribing statins:

1. A patient with chronic liver disease should take low-dose rosuvastatin or pravastatin. These statins are reliable protection liver, but they can not be combined with antibiotics and alcohol.
2. A patient who complains of muscle pain or has a tendency to such a disease is better to take pravastatin, since it has the least effect on muscle tissue of all statins.
3. It is dangerous for a patient with chronic kidney disease to prescribe Fluvastin-Leskol and Atorvastatin, since the drugs are too toxic to these organs.
4. Patients with high LDL levels are better off with rosuvastatin or atorvastatin.
5. When prescribing a statin to elderly patients, take into account that the drug provokes the development of myopathy by 3 times.

Scientists have not yet been able to determine how it works simultaneous reception statins and nicotinic acid, since the latter:

• Reduces sugar in diabetics.
• Provokes bleeding from the gastrointestinal tract.
• Exacerbates gout.
• Increases the possibility of developing myopathy.
• Increases the risk of rhabdomyolysis.

How to take statins and at what time

To restore HDL levels, statins are drunk once a day, preferably in the evening. This is due to the fact that during this period of time, the formation of lipids increases. But if atorvastatin or rosuvastatin are prescribed, then they can be drunk at any time, since they differ in prolonged action.

To improve the effect, adhere to some restrictions in food and lifestyle. For example: Minimize or completely give up alcohol and cigarettes. The amount of salt in meals should be limited.

It is useful to walk in the fresh air or do simple physical exercises 3-5 times a week for a minute. Such a load will improve the condition of the vessels and enhance the effect of taking statins.

natural statins

Some patients refuse to take statins for cholesterol because they are afraid of severe side effects. In such cases, natural statins are recommended to increase HDL levels. This is the name of specific substances that are contained in sufficient quantities in products:

1. Vitamin C. It is found in rose hips, peppers, sea buckthorn, currants, citrus fruits and cabbage.
2. Policonazole. Produced from sugar cane.
3. Niacin. It is rich in meat, nuts, cereals, red fish.
4. Monacolin. This substance can enrich the body by eating red rice yeast. They are presented as a dietary supplement but are hard to find.
5. Curcumin. They are enriched with turmeric.
6. Fatty acids (omega-3). Contained in sufficient quantities in vegetable oils (experts recommend choosing flax oil) and fatty fish.
7. Resveratrol. Found in red wine and grape skins.
8. Pectin. Bread with bran, buckwheat, pearl barley, oatmeal, cabbage, beans, carrots and apples are enriched with this substance.

Garlic, fermented tempeh, and miso are also considered natural statins.

Statins and other medicines

According to WHO and AAS, statins are mandatory in the treatment of ischemia, which is characterized by a high likelihood of complications and heart attack. The appointment of statins to stabilize HDL in a patient will not be complete, so the doctor also prescribes:

• Beta blockers: Bisoprol, Metoprolol.
• Antiplatelet agents: Aspirin, Aspicor.
• ACE inhibitors: Quadripil, Enalapril.

Statins used to be recommended only before bed to separate their effects from other medications, but now more and more leading scientists are leaning towards the idea of ​​taking combination drugs. On the this moment in laboratories, the combined drug Polypill is being tested, and in pharmacies you can already find Caduet and Duplekor, which combine Atorvastatin and Amlodipine.

If the norm of cholesterol is exceeded by more than 7.2 mmol / l, it is rational to prescribe the use of statins with fibrates. Such a decision should be made by a qualified specialist, taking into account individual indicators patient and all possible risks.

Indications for statins

In some cases, when a patient is diagnosed with non-progressive hypercholesterolemia, a specially selected diet, the use of natural lipid-lowering products and a healthy lifestyle help to lower blood cholesterol and, accordingly, reduce the risk of developing heart and vascular diseases. Natural correction of lipoproteins in the blood can reduce this figure by an average of 15%, but some patients, with the proper approach, increase this percentage to 30.

But even such good results may not always help in the case of advanced hypercholesterolemia or when there are cardiac pathologies.

The use of drugs - statins - helps to improve the quality of life and significantly increase its duration in atherosclerosis.

What are statins

Statins are a group of lipid-lowering drugs that inhibit the synthesis of certain enzymes required for the production of cholesterol by liver cells. In this indirect way, statins can significantly lower total blood cholesterol and LDL levels. In addition, the latest generation of statins are able to increase the concentration of high density lipoproteins, which is important in the normalization of lipid metabolism.

The result of the use of this group of drugs are the following effects:

• improving the function of the inner layer of blood vessels;
• reduction in the size of atherosclerotic plaques;
• suppression of fibrotic processes and hypertrophy of the heart muscle;
• elimination of the inflammatory process in the vessels;
• decrease in blood viscosity;
• improvement of systolic function of the left ventricle;
• inhibition of transplant rejection reaction.

For these reasons, the indication for statin prescription is a rather large list of diseases and pathological conditions that may not be associated with high blood cholesterol. These indications can be divided into absolute, when their use is mandatory to normalize the patient's condition, and relative, when it is possible to replace the prescription of statins with diet therapy or other groups of drugs.

Absolute readings

There are groups of patients who need to take statins, because without additional medical support, the risk of developing severe complications and even mortality increases significantly. Absolute indications for prescribing statins include:

1. Hereditary heterozygous hypercholesterolemia type II a, when the level of total cholesterol is above 10 mmol / l.
2. Dysfunction of LDL-receptors of hepatocytes.
3. Primary hypercholesterolemia IIa and IIb, if there were no positive results for 3 months of diet therapy.
4. Combined familial hypercholesterolemia.
5. Disorders of lipid metabolism of alimentary genesis.
6. Severe manifestation of atherosclerosis.
7. Severe coronary heart disease, when the risk of stroke or heart attack is too great.
8. Aneurysm of the abdominal aorta.
9. The defeat of the coronary arteries of any location with a stenosis of more than 50 percent.
10. Preparatory or recovery periods associated with reconstructive operations on the coronary vessels or the heart: coronary artery bypass grafting, setting up a grand stand, etc.
11. Diabetes mellitus with diagnosed cardiac ischemia.
12. Recently suffered a heart attack or a stroke.
13. Acute coronary syndrome.
14. The presence of arterial hypertension, when the probability of occurrence of cardiovascular accidents is estimated on the SCORE scale over 5%.

If we consider the absolute indications for the appointment of statins regarding the content of cholesterol in the blood, then we can highlight the following points when you need to take these drugs:

• total cholesterol level is more than 6 mmol/l;
• the total cholesterol level in patients with heart and vascular diseases is more than 5 mmol / l;
• the content of low-density lipoproteins in the blood is more than 3 mmol / l.

Therefore, the answer to the question at what cholesterol statins are prescribed will be a purely individual consideration of each patient and taking into account existing chronic pathologies. So, sometimes you need to take statins for more low rates blood lipid levels when there are one or more risk factors for ischemic heart disease: hypertension, male sex, elderly age, obesity, hereditary predisposition, etc.

Before making such appointments, the doctor must conduct 3 biochemical blood tests:

1. The first time when a patient complains.
2. The second - a week after receiving the first results for the final diagnosis of dyslipidemia.
3. The third - 3 months after diet therapy.

Relative readings

In addition to absolute, that is, mandatory indications for prescribing statins, there are also relative ones when it is desirable to take these drugs, but others can be dispensed with. therapeutic methods or groups of drugs. Such indications include:

1. Cases of sudden cardiac death in relatives of the patient, whose age has not reached 50 years.
2. History of unstable angina.
3. Low risk of developing a heart attack.
4. Diabetes mellitus type 1 or 2 without diagnosed coronary heart disease.
5. Obesity.
6. Age over 40 years with a low risk of developing cardiovascular pathologies.

In each case, the advisability of taking this group of drugs should be assessed by the attending physician, taking into account the individual characteristics of the patient and his chronic and hereditary diseases.

The amount of cholesterol required to take statins

Many patients are interested in the question at what level of cholesterol should statins be prescribed. After all, different patients with the same level of lipoproteins in the blood can be given different recommendations for their normalization: one will be prescribed a diet, and the second - drugs.

Doctors have their own opinion on this matter. First you need to remember what level of fatty fractions in the blood is considered normal:

• OH: less than 5.2 mmol/l;
• LDL: less than 3-3.5 mmol / l;
• HDL: more than 1 mmol / l;
• TG: less than 2 mmol / l.

It is to such values ​​that one should strive, but not all people, due to individual characteristics and diseases, manage to maintain these indicators at an optimal level.

The decisive factor in the appointment of statins is not an increase in a certain lipid index, but the level of risk of developing complications. To calculate this risk, various tables and calculators have been developed today (for example, the SCORE scale).

Guided by this principle, the mandatory appointment of statins is a clinical picture when the following two points are simultaneously present:

1. The level of lipoproteins exceeds normal values.
2. The risk of developing cardiovascular disease is above 5% in 10 years.

At the same time, it is worth considering some systemic diseases, which make their own adjustments to the normal functioning of lipid metabolism. So, if in patients with diabetes mellitus or atherosclerosis, total cholesterol is above 4.5 mmol / l, and low-density lipoproteins are above 2.5 mmol / l, then such patients must definitely take statins.

Some patients with normal blood lipid fractions are still on lifelong statin therapy. This practice is used in patients who, in the absence of changes in the level of cholesterol in the blood, are diagnosed with a high risk of developing atherosclerosis. These risk factors include age, bad habits, hereditary predisposition, and many others.

What statins are prescribed to lower cholesterol

To date, there are 4 generations of statins that affect fat fractions in different ways. Consider how they affect the level of atherogenic low-density lipoproteins, taking into account the intake of the highest daily dosage:

How is the appropriate statin prescribed? Their appointment does not depend on the percentage of cholesterol that needs to be adjusted, but on the overall effectiveness of the drug and its safety, that is, there are no side effects.

Therefore, statins are most often prescribed today. latest generations– Atorvastatin and Rosuvastatin, which are the safest for health when long-term use, quickly and stably reduce "bad" cholesterol, and also increase the concentration of "good" cholesterol in the blood - high-density lipoproteins, which is important for the normalization of lipid metabolism.

For each person, depending on the data of his lipid profile and the presence of chronic diseases, an individual dosage is selected. So, if lipoproteins in the blood are slightly elevated and there is no history of severe coronary diseases, the doctor may prescribe a daily dosage of Rosuvastatin in the range of 5-20 mg. If low-density lipoproteins greatly exceed the permissible limits and there is a history of cardiovascular pathologies, for example, ischemic disease, you need to take this drug at a maximum dosage of 40 mg per day.

Can you stop statins?

Many people walk out of the doctor's office, bewildered by the fact that they have been assigned to take statins throughout their lives, although the patient himself feels relatively well. Is it possible to refuse their appointment?

Patients need to understand that no doctor will prescribe statins unreasonably, since there are absolute and relative indications for their use. So, in the first case, statins should be taken without prior replacement therapy. Relative indications allow for the first 3 months of observation of a patient with high cholesterol to use diet therapy, prescribe other lipid-lowering medications, or conduct other treatment.

Therefore, if the doctor immediately prescribed statins, you should immediately purchase them and start taking them, since life expectancy and its quality may depend on timely treatment.

There is another side of the coin: you can start using statins only on prescription! If you and your neighbor have the same symptoms and the doctor prescribed statins for her after the examination, you can’t buy and take the same ones. Firstly, they are prescribed only according to indications and after diagnostic procedures. Secondly, statins have their own side effects, especially if they are taken without medical supervision and individual selection of the daily dosage.

How long to take statins

In order to maintain lipid levels at an optimal level, you need to take statins for life. Most patients are frightened of this prospect and stop drinking them when all indicators of lipid fractions stabilize, fearing the development of side effects.

This cannot be done, since ongoing studies have shown that with a ten-year intake of statins, the likelihood of negative consequences has not increased. Therefore, if the doctor prescribed a long-term, up to lifelong, use of statins, you need to follow his recommendations, since there were weighty indications for this.

The use of statins is largely aimed at lowering the level of cholesterol in the blood, but they are no less important in terms of improving the quality of life of the patient and prolonging his life. Therefore, if the patient has indications for their use, the doctor will definitely prescribe lipid-lowering drugs, choosing their dosage on an individual basis.

All information on the site is provided for informational purposes only. In case of symptoms of the disease, contact a specialist.

So, the first step towards lowering cholesterol is to change your diet. Not a "diet", but a change in eating habits. I don't really like the word "diet", it usually means something short-term. If you can "diet", then it is logical to assume that sooner or later you will have to "get up with" and go along the "familiar route". Therefore, we are not talking about a diet, but about the need to reconsider your eating habits for life.

In a nutshell, I usually use this formula: "from meat to fish and unlimited vegetables and fruits."

If we discuss nutrition issues in more detail, then I suggest looking at the table, which was developed by international experts on atherosclerosis.

However, "diet therapy" for high cholesterol, unfortunately, is not always effective. Firstly, few people are ready to completely abandon the usual culinary delicacies. In my practice, there are not so many such persistent fighters "for the cleanliness of refrigerators".

Secondly, as we remember, the intake of cholesterol from food is only 20%. Therefore, it is very sad to hear the stories of patients about how a doctor, with a double increase in cholesterol, instead of prescribing therapy, says with a sigh: “Well, what are you, my friend ... You have high cholesterol ... You should diet ... ".

Therefore, sooner or later the question arises: is it time to take drugs that lower cholesterol. And if so, which ones?

Statins for cholesterol. Myths about statins: benefits and harms

Mankind has come up with a lot of drugs to lower cholesterol. Now there are four groups of drugs on the market, about a dozen more groups are under study. But in 99% of cases, doctors prescribe drugs of one group - statins. Why?

The fact is that statins are the only group of cholesterol-lowering drugs that not only lowers the level of "bad" cholesterol, but also reduces mortality, and therefore increases life expectancy.

What is the secret? The fact is that statins not only lower cholesterol, but also reduce inflammation (and inflammation and endothelial dysfunction are key factors in the development of atherosclerosis). Statins have the ability to stabilize atherosclerotic plaque and prevent its rupture, and therefore prevent myocardial infarction and other catastrophes.

We currently have three drugs on the market - atorvastatin, rosuvastatin and the almost disappearing weak simvastatin.

Surprisingly, statins are the group of drugs surrounded by the most myths and legends. I will try to answer the main objections that are expressed by patients at the reception, as well as those common in publications on the Internet.

1. If I take statins, I will never get off of them. Statins are not addictive in the narcological sense of the word. If you stop taking them, then cholesterol will rise to its previous level and the risk of complications will increase again. Indeed, statins should be taken for life, just as we brush our teeth for life and do not complain that we were “hooked on toothpaste.” Brush your teeth so that there is no caries, take statins so that there is no heart attack. Everything is simple.
2. One we treat, another we cripple. Statins, of course, protect blood vessels, but they increase the risk of cancer, dementia, and liver and muscle diseases.

In medicine, when using a particular drug, the benefit-harm ratio is always evaluated. To develop one new case diabetes, 250 patients need to be treated within 4 years. During this time, without treatment, 6 people will die from a heart attack.

An increase in liver enzymes, AST and ALT (markers of liver damage), against the background of standard doses of statins, occurs in 2 out of a thousand people, while most often it has no clinical significance. Much stronger liver alcohol and fatty foods damage, but this, as a rule, does not bother anyone.

As for cancer and dementia, these myths have long been debunked in serious research. On the contrary, oncologists are increasingly noting a slight antitumor activity statins.

1. In fact, cholesterol drugs are all a conspiracy of pharmaceutical mafia. After all, they do not affect well-being.

Yes, it is very difficult to accept that there are drugs that affect the prognosis, life expectancy, and not a momentary symptom. AT modern world in developed countries, drug manufacturers are closely monitored by both governments and public organizations, and competitors. It is simply unrealistic to bring “fuflomycin” to the market and sell it around the world just like that. By the way, up to 50% of studies in cardiology end with a negative result, and it is impossible to falsify them.

1. And yet it is better to use natural remedies, because they are natural and harmless.

Alas: not a single herbal preparation based on garlic, parsley, not a single dietary supplement in studies (and such ones were carried out!) Demonstrated an effect on survival.

Treatment of atherosclerosis

Here it is time to answer the main question of all times and peoples: But how can you clean the vessels??

Dear readers. The vessel is not a sewer or water pipe. We do not have a magic pill to "dissolve" an atherosclerotic plaque if it has already formed there. Consider anyone who promises to do this to you a charlatan and a personal enemy. Alas, none of the molecules on the planet (whether chemical or plant) is able to reverse the processes of atherosclerosis.

But there is good news. We can stop plaque from growing, we can stabilize it and keep it from rupturing, we can reduce inflammation— serious factor progression of atherosclerosis. And if the plaque is so large that it interferes with blood flow (as a rule, this narrowing is more than 50%), then the issue of surgical treatment is discussed.

But in fact, it is not so much the size of the plaque that is important, but how much it harms in this particular place, in which vessel it is located, whether there is a roundabout blood flow. After all, what is 50% - it is sometimes 55%, and sometimes 45%, so before discussing the issue of surgery, it is important to analyze the symptoms - how pronounced is angina pectoris, how limited is physical activity, whether all the possibilities of drug treatment have been exhausted.

There are several types of vascular operations. Very common stenting- an operation in which the narrowing zone is first inflated with a balloon, and then a special spring-stent is inserted into this place. She, like a frame, rises inside the vessel, preventing it from falling off.

The second treatment option is shunting. A shunt in translation into Russian is a “bypass”. A section of another artery or vein is sutured so as to bypass the affected area of ​​the vessel.

The third variant of the operation, which is used to treat atherosclerosis of the carotid arteries, is endarterectomy. In this case, the vessel is incised and the plaque is "scraped off" along with the inner lining of the artery.

• Do a lipid profile analysis.
• Define treatment goals (LDL levels depending on your risk group).
• Review your diet: try to limit animal fats. Plant foods do not contain cholesterol at all.
• Talk to your doctor about the need for statins.
• If statins are prescribed, they must be taken continuously. You cannot stop healing when the target values ​​​​are reached.

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Comment on the article "Diet for high cholesterol. Statins: benefits and harms"

Cholesterol can be perfectly lowered by a diet without any statins. Women after 40: cholesterol in the blood and 8 more examinations. To do this, doctors have developed a special therapeutic diet to lower cholesterol, the maintenance of which helps prevent...

With high cholesterol, which doctor?. Doctors, other medical staff. With high cholesterol, which doctor? It turned out that my mother had a very high cholesterol level. My mother lowered her cholesterol from 10 to normal in half a year.

Cholesterol is high. Need advice. Weight loss and diets. Cholesterol cannot return to normal in one month if it has been elevated. You need at least three months. Although my mother eats very little in general, simply by force, she doesn’t eat anything fatty, and cholesterol is elevated at the same time.

Discussion

My cholesterol was very high. Very local doctors were going to put me on medication. Which I didn’t want at all at my age. I lowered it for quite a long time. units, so it’s hard for me to judge how much your indicators exceed the norm), then you won’t help yourself with diet alone. Physical activity, regular, is simply necessary. Until I started exercising regularly, my cholesterol decreased quite a bit. I have it and now it is already a little higher than the norm, but not much. Medicines are no longer forced.
Yes, and take fish oil, it is also very useful.

Cholesterol cannot return to normal in one month if it has been elevated. You need at least three months. Although my mother eats very little in general, simply by force, she doesn’t eat anything fatty, and cholesterol is elevated at the same time. Medicine is a dark business! I advise you to stay on a strict diet for another 2-3 months, if it doesn’t help, then talk to a doctor. maybe some herbs for prevention to drink.

cholesterol. Tips, recommendations. Medicine and health. Diseases, symptoms and their treatment: tests, diagnosis, doctor, medications, health. I have high cholesterol, tell me some folk remedies to reduce it.

Discussion

how old are you and what is your cholesterol level, it is better to take another LPNI and HDL. maybe you have a lot of good olesterol and little bad. write, in our department they deal with family hypercholesterolemia, and if there are problems, we will help.

Olive oil removes bad cholesterol well, every day in the morning before breakfast, flaxseed is also good. Only all this must be taken for a rather long time, there will be no instant action. I read about alfalfa, but did not check. And if faster then pills.

If there are no signs of atherosclerosis - then the diet, if there are signs of even non-stenotic atherosclerosis, then in the absence of elevated Cholesterol pills are statins, I guess? It's not so easy with them. They are really good at lowering cholesterol, but...

Discussion

The question is not simple. How old are you? Are your periods normal? Do you have risk factors: smoking, hypertension, physical inactivity, the presence of early vascular events in parents and siblings (stroke, heart attack in women under 65, men under 55)?
If you at least have something + you are obese, you need to look at the condition of the brachiocephalic arteries. If there are no signs of atherosclerosis, then the diet, if there are signs of even non-stenotic atherosclerosis, then in the absence elevated enzymes AST. ALT (you have hepatitis) 2.5 times you need to take statins. I apologize for the tedium - but these are international European recommendations, which cardiologists are guided by in their work.

Discussion

Returning to the topic of cholesterol. Thank you very much for your answers. Especially for the advice to go to a cardiologist. Can you imagine, it didn’t even occur to me :) .
I will lay out the parameters from the results with the highest risk (before the measures taken later - quit smoking, sports, diet).
Cholesterol total - 6.73.
Triglycerides 0.99
Cholesterol HDL-1.02
Cholesterol LDL-5.25
Cholesterol VLDL-0.45
To anthrogenicity 5.73
Now he has a total cholesterol of 6.2. We do not know the rest.
We have been working under a contract in one of the countries of the Persian Gulf for 10 years. So it’s not so easy with doctors here. Against the backdrop of excellent hospitals with the latest equipment, the specialists themselves ... mmm .. they can prescribe something very strange. more than once. Moreover, doctors from different countries. So we trust only ours, so I got into the conf. There are not many other exits :))))))

First of all, you need to make sure that the analysis was carried out correctly. The test is done in the morning, on an empty stomach, you should refrain from eating for 10-12 hours.

High cholesterol levels can be determined by genetic causes - the ratio of low and high density blood lipoproteins. If in fact such analyzes, you need to check this too. If this ratio is normal, then the question of cholesterol in food is not ...

Discussion

Before taking a cholesterol test, for the reliability of the results, you must not eat for 10-12 hours. If your mom hasn't been warned about this, it's no wonder your cholesterol is going through the roof. And so, in general, exercises, vitamins, diet, green and red vegetables (peppers, tomatoes, cabbage, lettuce, green onions), garlic, fish (including fatty ones, like salmon and herring), sunflower, olive or corn oil is desirable , green tea (but not at night), completely exclude margarine and others like it, as well as products sweetened with aspartame and synthetic fructose (high fructose syrup). You will also have to give up coffee. Fruits are very useful - apples, apricots, raisins, as well as oatmeal and buckwheat. As for butter, beef-veal, eggs and liver, it has not been proven at all that the animal cholesterol contained in them passes into human cholesterol so easily and simply, everything is just good in moderation. But the fact that fructose, unlike glucose, turns into cholesterol in the human body is a fact.
Some cholesterol-lowering drugs have already been banned in the States, others, like Lipitor, are next in line - they do more harm than good.
Regarding high blood pressure - it can be caused by the kidneys, did they check them for her? Usually, with hypertension, doctors advise limiting table salt, and also taking potassium supplements.

Vitamins "Aevit" help lower cholesterol. Still the use of garlic, oatmeal - they reduce too. Exclude from the use of margarine, veal (there is a lot of X in a growing organism), remove the skin from the bird, no more than 2 eggs per day. Medicines to reduce H. are very aggressive, they should be taken only under the supervision of a doctor.

So what? They almost never go home anywhere in the world. WHO is an office for third world countries that writes recommendations for developing countries on how to get rid of worms. If someone promises to clean the vessels, then these are charlatans, this can only be done surgically. No matter how much we reduce cholesterol to a very low level in experiments (now we have learned to reduce it very, very low), people still live longer. We don't use the word "diet" at all when talking to patients. At the same time, you need to write honestly. For example, quitting smoking, lowering blood pressure, getting rid of excess weight and exercise is as effective as, or even better at reducing the risk of heart disease than, medications. I returned yesterday from Geneva, there was a European Lipidological Congress, and a question was asked about specific cholesterol regulators.

But any predisposition can be realized, or not realized, because it is just a predisposition. How many calories does he burn per day? His energy costs can pay off with a handful of rice. There are no such situations in cardiology that could be treated with a course. There will be no article in the Criminal Code for the independent abolition of statins. Active ingredients:

Anatoly N. 02.12.2011 at 08:20 Link I have been suffering from coronary heart disease for many years, the cardiologist is constantly changing drugs and treatment regimens. Secondly, it happens that a person takes up his mind and really changes his lifestyle, loses twenty kilograms, quits smoking, starts to take care of himself, rebuilds his brain, throws all nonsense out of his head. First, WHO should not be deified. You come to the Caucasus - they put a dish in front of you: fifteen khinkali for one. My husband has been taking various statins for about 15 years. He was seventy-five years old and came to me for shortness of breath. Because here on the surface really lies calcium. The question, of course, is the extent of these movements.

Is it possible to stop drinking statins: in more detail

Any house, as you know, stands on a foundation, and so the foundation diseases and there will be the very risk factors: hypertension, high cholesterol, smoking, obesity, stress... Is it necessary to lower cholesterol? Quitting smoking often requires motivation. When I came to the clinic twenty years ago, I got into a group that dealt with arterial hypertension, and I also began to deal with this problem and still deal with severe forms of hypertension.

If you come to Austria, ask: "Where can I buy Cerebrolysin here?" They will say: “Are you crazy, we don’t have it.” The next question is about the safety of these drugs. In mathematics, there is the concept of N, and there is N-1. But someone can reproach me that I appointed statin? I gave him the opportunity to live to eighty years, and these changes are age-appropriate, nothing indicates that they arose during statin therapy. It is difficult to force yourself to take three, four, five drugs that do not affect well-being. The effect of some neutral solution being injected into a vein is very well studied, in particular, the placebo effect is well studied in pain relief. They say that while you drink it, you get the effect.

This is our super task. More obesity? Maybe. For example, diseases accompanied by chronic inflammation. All these drugs are not Russian, they are all bourgeois, produced in capitalist countries, but they are not used anywhere in the capitalist countries themselves. This is how the antiarrhythmic drug Quinidine appeared (another thing is that it then disappeared, because it turned out to be too toxic).

They took away the social component, the doctor stopped going to the house. And nothing will happen to the kidneys. They began to tax those who produce meat and milk, and, on the contrary, exempted those who produce vegetable raw materials from duties. There are additional "small" factors. What happened to you? You are describing some situation related to psychotrauma; most likely, this is not the beginning of hypertension.” Cardiac glycosides, for example, are still a herbal preparation.

Is it possible to stop drinking statins: what you did not know

Therefore, we treat atherosclerosis, but we do not set ourselves the task of dissolving these plaques. Therefore, the use of magnesium is completely meaningless. For example. Like Dovlatov: “I only smoke when I drink. Behind the predisposition lies a certain combination of genes that tells us with a certain probability that this person will have a higher risk of myocardial infarction than another. Yes, that's how weak we are, we can only offer this now. Yes, you will limp, but as long as you wear a prosthesis, it gives you the opportunity to walk. valentine 20.02.2012 at 04:10 LinkAtoris took 4 months.

And some brilliant neurologists know this. When discussing the drug on forums and websites, there are a lot of questions about how to take the drug correctly, what is the duration of treatment. Do you know how many calories are in seeds?

Great amount. Going home, physiotherapy, which is also not particularly needed by anyone. No, they do not affect the pressure in any way.

For a healthy person, for a person without heart failure, without kidney failure, for a person who does not take medication, there is no lower pressure limit. There is a very simple recommendation called "Keeping a food diary." But in fact, now 90% depends on him, on how much he can influence his lifestyle and his risk factors without drugs. Sometimes elderly people forget to take, skip taking medications, who need a lot of medications, who take five to seven or even more medications. This is the purest placebo effect. Life expectancy is based on 50% genetics, that is, hereditary predisposition. This is proof that non-drug therapies work. How are drugs made? I really don't like it when traditional medicine and our chemical medicine are contrasted.

Inflammation is the leading mechanism for the development of atherosclerosis. Our drugs, beta-blockers, are not addictive, they do not have this mechanism, they are not drugs. Aspirin does not need to be taken "just like that." I saw a lot of different things and forgot how to generally speak categorically, because anything can happen. It turned out that these publications (these anti-statin publications are all over the world, not only here) increase mortality. This is well known to cardiologists. Although they are often prescribed for hypertension precisely because the more “blocks in the foundation”, the stronger atherosclerosis will stand. And finally, one more part.

Clinical studies of these drugs that would allow their use in the world do not exist. There are no courses in cardiology, with rare exceptions, after a myocardial infarction, Plavix is ​​given for twelve months. By the way, we still need to look for a doctor who would write so many times in the conclusions: "He does not need medical treatment." This is the lumen of the vessel, which is 60% narrowed by an atherosclerotic plaque. Nitroglycerin is only used as a spray in people during an angina attack. It was summer. Still, of course, it is very important not only how much, but also what exactly we eat.

Forty percent of what can lead to the realization of this predisposition are risk factors. Fraction? No. You know perfectly well that mortality is absolutely not based on this. In most countries it is registered as a dietary supplement, in some it is prohibited. But, in their opinion, a plate of lamb per day is not food. Behind the TV, seeds.

Some men call a decrease in erectile function as a side effect of taking the drug. In fact, there were not so many drugs. Atoris (Atoris) - reviewsAtoris refers to drugs of the statin group, as a result of which the level of cholesterol in a person's blood decreases, and thus cardiovascular diseases are prevented.

When I gave a lecture in Dagestan, I said: “How are you dripping Cerebrolysin? You look what he is made of, otherwise it will not be good, it will be inconvenient in front of the authorities. You've tried changing your diet and staying active, but you haven't reached your desired cholesterol levels. If a young person can run, jump, ski, swim in the pool, then a patient with severe heart failure should at least move around the apartment, at least get up and cut circles along the corridor. If I explained everything to you, you understood everything, and, therefore, you work with me in a team, and if you don’t work in a team, then I’m sorry. For the sake of this, all this was created, all this was written. That is, it is not a drip in itself that heals, but some kind of drug that is dripped into a vein.

Patients say: "Here I will take these pills, what should I feel?" You shouldn't feel anything, absolutely nothing. Obesity combined with in a sedentary manner life also greatly affects the development of atherosclerosis. And often we spend them too little. The latter, with the help of the so-called. The respiratory chain allows organisms to produce energy in the form of ATP. About droppers I typed five pages of text on the computer, and then I decided: “Why, actually, only to her?” - and published it on the Snob portal and on Facebook.

It makes no sense to expect results in 2 weeks. She did blood biochemistry, the tests were not very good, they prescribed Atoris. What's the point of taking pills if they don't affect the blood in any way? Or maybe they just couldn't help you? As I understand it, the cholesterol did not go down in the end?Android 12/09/2011 at 05:51 LinkPeople, don't take statins, they destroy the liver!

Although many doctors consider these drugs to be relatively safe, there are already studies that prove them. harmful effect! My father took Atoris for a long time, as a result he died of cirrhosis of the liver. When you have gallbladder surgery, you pay money once or don't even pay, but when you go and dissolve stones for years, you are hooked on it. They rebuilt the country's economy: they switched from the meat and dairy industry to vegetable products.

How can you invest in your own life extension? After all, we are talking about what will happen to us in twenty or thirty years. In Russian, the noun "diet" is governed by the verb "sit", and since you can go on a diet, you can get off the diet, which usually happens. We jokingly say to students: “If you are asked what is the cause of such and such a disease, then answer: “Genetics”, you will not be mistaken.” In any case, we do not draw energy from the air. I looked on the company's website for a warning about this side effect, but found nothing.

The body struggles with the prohibition to live normally, and therefore taking statins causes many adverse reactions that drastically reduce the quality of life. Everyone needs to move, all the time. Questions about hypotension. But, when you have severe atherosclerosis in your vessels, then it’s my job to stabilize this place and prevent it from bursting. But there is one of the leading risk factors, the severity of which has changed dramatically over the past twenty years. How and what? It's so difficult." If someone invented something to treat, to dissolve the plaque, it would be a revolution that would eclipse all the Nobel Prizes.

The use of an antispasmodic in the treatment of hypertension is an idea of ​​the 50-60s of the last century. And we came to the conclusion that in Finland there is a very high severity of risk factors: a developed meat and dairy industry, a lot of alcohol, a lot of people smoke. But that's not even the problem. Where to direct to throw these or those derivatives of cholesterol in accordance with the address tied to the alcohol group of cholesterol.

The next question is: “Is it possible to quit if I smoke for a long time?” - "Can". A question for you, if you can, answer, how much more Atoris should I take? Is it possible to take breaks in use. Often there are questions about the liver. He underwent surgery to remove a thrombus in the femoral vein and was prescribed Xarelto 1 per day for 6 months. detralex for a course of 2 months (he has been drinking it longer), atoris or atorvastatin 20 mg 1 r.v.d. Life expectancy is always at the forefront. The same goes for fish oil. There is no lower limit of normal. If for some reason it breaks (and the reasons can be different: a pressure surge, an emotional conversation, stress, smoking), then a person will suddenly grab his heart and either he will have a heart attack, or he will fall and die. The rupture of an atherosclerotic plaque and myocardial infarction is now the main slide, for which everything was started.

But after two weeks, cholesterol will rise again. But the biggest part is the risk factors, how we manage them. There are few people who can resubordinate their entire lives to counting calories. Nothing will happen. And within a few weeks, her memory recovered. The blood flow stops, a blood clot develops, and all those tissues that are behind this place die off. But atherosclerotic plaque is completely different in composition. Why?

Because the basis for reducing the incidence of cardiovascular complications is lifestyle modification. These are family traditions, these are hereditary traditions. I asked the doctor, he told me that this is one of the side effects of these pills in some people immediately caviar seizes, in others (like me), after a while. Yes, they are not popular, they are somewhat repressive, they prohibit smoking, they fine, but this must be done in the name of the health of those who will replace us. However, often people who are fascinated by non-traditional methods, who “as if” also understand that not everything depends on medicine, tell me: “Pharma mafia pays you to put patients on pills, perform operations on them. For example, I couldn't. A patient came to me, an elderly Armenian, very orthodox. And sometimes the motivation is positive.

Not without reason it happens that when the patient continues to smoke, the effect of smoking eliminates the effect of statins. As patients usually say. When they criticize the reform, they say that everything has been taken away from us. Yes, we cannot cure hypertension. I have a very touching story in my memory, I described it in the second book.

It is both so and not so. This may be your specialty. For everyone over forty, Malysheva recommends taking aspirin to thin the blood. Smoking is a drug addiction, a very powerful addiction. It is very difficult to remove from them those who are psychologically addicted to it. Statins have been shown to reduce the risk of heart attack, stroke, and death in people with high cholesterol. which at risk for heart attack and stroke. A young, forty-year-old man has just come to me with "jumping" pressure, with the onset of hypertension. Well, what about the fact that you brush your teeth every day, wash your hands every day? Well, then teeth, then hands. By the end of the year, we are asked: “How did you reduce mortality from cardiovascular diseases”?

I will honestly and frankly tell you that it is possible to reduce mortality from cardiovascular diseases in one year only by postscripts. I must say that the remaining 40% is still enough to supply oxygen to the tissue of the myocardium or brain, that is, this person may very well not feel anything bad at the moment. I have a good attitude towards Pechatnikov.

Now questions. You get money for this, but you need to think right, breathe right, think right, eat right, do yoga, you need to drink dietary supplements, you need to study physics, the laws of thermodynamics, etc.” Just in case you don't need to drink aspirin!

It turned out that the number of prevented heart attacks is very small, and the amount of bleeding (aspirin can cause bleeding) is quite significant. The choice of treatment is not so clear-cut for people with moderate elevated cholesterol levels and small risk factors for coronary artery disease and heart attack. Why are they needed if we are fighting them in the 21st century? Are we fighting nature? Mother nature has made enzymatic systems for us so that cholesterol is synthesized, and we are fighting it. They were abandoned precisely because they are addictive and eventually ceased to work.

Your health is dear only to you and your loved ones! Lera 04/09/2012 at 20:56 LinkOlga. if you do not complicate, describe what problems began. They are terribly frightened, they come running, they say: “Listen, nothing bothers me, but yesterday we met with classmates, and my friend, with whom we drank, ate, smoked, turns out to have already died. And they parted ways.

It is how we eat, how we move, how we behave, how we react to what surrounds us. Drugs are too expensive for you if your insurance doesn't pay for them. Of course, statins should be prescribed according to indications, and not to everyone. And I understand that if I had been as smart then as I am now, or if it were now, they could have been saved. Omega-3 is registered as a drug in many countries and in Russia. And when young, 25- and 30-year-old patients came to us, we turned them inside out, trying to find the cause of secondary hypertension. Sometimes there are muscle pains. He perceives pills as a load, but the pills, of course, help during this time. Stress and Hypertension Stress is not even a small factor, but it is very difficult to calculate and very difficult to influence.

Statins lower LDL levels by 18-55%. We must be partners. I generally work in federal institution, I absolutely do not care who will drip a dropper, who will not. At the start, we used a combination of three drugs. The patient says: "Yes, but I have it so high all the time."

On the one hand, I understand why: because cholesterol does not hurt. May cause dysrhythmias, especially in the elderly. Does wine alcoholism exist? 20 comments from site readers peoples Pharmacy suki65 5:37 am. Such that a person has real hypertension with a pressure of 180-200 mm Hg. Art. and suddenly he went into a stable remission, I hardly saw him. She turned out to be a very strong-willed woman and changed her lifestyle so much that we either left tiny doses of one drug, or completely canceled therapy.

But then a reader from Omsk wrote me an ordinary paper letter, and I, of course, could not help answering it. Seeds, some candies. Although the majority of users tolerated the drug well, when analyzing reviews, we also encountered examples of leg cramps, headaches, nausea, and several cases of worsening liver tests while taking Atoris. Yes, it's not cool and not that impressive, it's not physical therapy. The older a person is, the stiffer his arteries are, and the mechanism of this muscle spasm, narrowing of the artery, as a rule, is no longer present in an elderly person, there is already a hard calcified plaque. There is laboratory analysis but it is not routine. This is not about our North Karelia (Kem, Kandalaksha, Chupa, Loukhi - whoever went kayaking knows ...). Omega-3s affect triglyceride levels, yes. If you stop taking the pills, you will have hypertension again, you will have high cholesterol again, you will have high sugar again, you will have asthma attacks again. When the lumen of the vessel is almost closed, it must be opened, unfortunately - this is only surgery.

Irina 01/03/2013 at 01:16 Link My lipid profile worsened after I had part of the thyroid gland removed. That's thirty seconds: one circuit of a neuron in my brain and one movement of a pen. Has no analoguesApproximate cost: 318 rubles. Most likely you are hiding the main etiology of your dad's disease.

You will notice that we are discussing the main foundation factors in order. Yes, it’s unpleasant, before I could call home, but now I have to drag a patient to the hospital, it’s not convenient, it’s not comfortable, but this has nothing to do with medicine. It is naive to think that they closed hospitals, closed the polyclinic - and therefore the death rate increased.

80% of cholesterol depends on how our synthesis systems are configured. The second reason is that in relation to many drugs. in particular, the same statins, there is a huge counter-propaganda. I repeat once again: it is very good to talk about any healing non-drug technologies while you are healthy, while you do not have all this splendor.

A serious motivation, especially for men, is the death of friends and classmates. That's why I bought your four books, waiting for the release of the fifth. In one case, a woman asks if she can stop taking the drug or reduce the dosage if her cholesterol levels have already returned to normal. It happens, but very rarely, and this is just the exception. And he says to me: "I eat very little." If we don't get enough, if we overeat, that's the key to developing this plaque.

It is produced only for the Russian market, because it is used in Russia, which means that you can sell it to us for crazy money. Cortexin is the same. Do you think it does not affect life expectancy? This is very influential. My father died at sixty from a myocardial infarction, and my aunt died at fifty-seven from a stroke with very severe hypertension.

I kept trying to find the source of this information, but most often the source is some kind of popular science publications, which it is not clear to whom they belong. Severe pulmonary insufficiency, when the lungs are literally burned. And I drew this picture for this book: imagine that cardiovascular disease is a house.

The effect of these drugs has not been proven in clinical studies. Do not do this. It is with a steady increase in pressure in calm state we say that you need to take medications. The same is the treatment of hypertension with pills. Everyone needs to move, all the time. Sometimes it is objected that the body needs cholesterol, all steroid hormones are synthesized from it, it is used to build cells (although there is not cholesterol, but other fats go - phospholipids, but this is not important). As a pleasant side effect, improved digestion and reduced risk of stone formation in the biliary tract. Unable to live in the absence of oxygen.

Why does this help then? And because, as a rule, hospital a person lies, something is dripped into his vein (pig brains) and in parallel they also give pills. For the past 5 years, all my patients have been taking Atoris. Because the chance of recurrence is quite high.

The raw materials from Norway are most appreciated. And who wrote this is completely incomprehensible! Just yesterday, at our European event, a publication of 2015 was shown. Olga 04/09/2012 at 12:55 Link I had high cholesterol, the doctor prescribed statins instead of checking the liver. What are these drugs? Let's list them, they are probably familiar to all of you. Therefore, no one dissolves stones in the gallbladder now. Sometimes they faint, and that's okay.

Hand washing is the prevention of intestinal infection. Once he gets into bed and doesn't get up, the prognosis is very poor. But, alas! The cardiologist recommended taking the beds. Patients say: "I smoke very little." Very hard to get into thought that the drugs that I take today are an investment in the fact that I will die not at sixty-five, but at eighty. This is the main side effect of statins: life expectancy increases, mortality decreases. And we prescribe drugs when there is already stable hypertension.

The same if someone came up with a cure for ARI. The goal of treating a stroke patient is to prevent repeated stroke. The first book is called "How to live without a heart attack and a stroke", and we named our lecture after it. To reduce your risk of coronary artery disease and heart attack, you will need to lower all your risk factors, not just your cholesterol. Cardiovascular health is 90% dependent on us, on what we do. These deaths could definitely have been prevented. There are no such pathological processes that could be removed in courses, and then wait until they grow again. Why did this happen? Are we getting worse?

Nothing like this. Magnesia is an antispasmodic that relieves pressure (then, by the way, the pressure rises, a rebound effect occurs). As a rule, early cardiovascular deaths in the family or early cardiovascular diseases can be traced in such patients. Thanks to hygiene habits, thanks to the fact that we have learned to brush our teeth and wash our hands, humanity began to live longer. Just like we give a prosthesis to a person without a leg, and he says: “How is it? It's not a cure. I'm in this case I absolutely support all the most aggressive, repressive, unpopular measures that our state takes, this is one of the few things in which I support our state - in the militant part of tobacco legislation. It's just that these drugs allow you to live to this age, to these changes. Hypertension, unfortunately, is not a disease that can be transferred into a stable remission and stop treatment. In ancient, primitive man, the level of physical activity was colossal.

And how to calculate the severity of this risk factor? It is not customary to talk about him, it is very difficult to influence him. Are there other reasons why you don't want to take cholesterol-lowering drugs?

Statins and combinations of statins are the most effective and common cholesterol-lowering drugs. We are not photosynthetics, we do not receive energy from the sun, we do not receive energy from mother earth, but at least we do not get in industrial quantities sufficient to get better. And it looks like medical help is provided. I always answer this way: apparently, it was destined for me to become a cardiologist - at a very early age, two people very close to me died of heart disease. How we eat, cholesterol depends on only 20%. On the contrary, with regard to the kidneys, these drugs are nephroprotectors, that is, they protect the kidneys. But before there were “long” nitrates - Nitrong, Trinitrolong, Sustak.

Relatives at home say: “Sorry, he left, we don’t know when he will be.” Latvia is a small country, it does not need rocket fuel, and the professor brilliantly solved this problem. That's why we say now that statins are not just cholesterol-lowering drugs. This is a thin covering of an atherosclerotic plaque.

For example, I try never to prescribe medications when they are clearly not needed. The reduction of the social component is necessary in order to leave the main thing - to leave the vascular centers, so that patients with myocardial infarction could be helped, so that they could put pacemakers, do bypass surgery. More than ten years ago, when we were still graduate students, we wrote a small pamphlet "The School of Hypertension", it was published by the Geotar publishing house with a circulation of 3000 copies and sold out instantly. They are produced exclusively for the Russian market. We don’t have and can’t have, in principle, the physical activity that we had ten thousand years ago.”

You don't have to refer to the WHO all the time. Correctly. Out of 50,000 patients, not one died of cirrhosis. It's the same with cholesterol medicine. This becomes a problem when there is heart failure, when the heart contracts so badly that it cannot pump blood, and vascular tone drops. By the way, in the 90s, products that affect cholesterol were actively promoted in Finland, and this company as a whole led to the appearance on the shelves of a huge number of dairy products with 0 fat content. Unfortunately, the main problem in the treatment of hypertension and in general the treatment of all diseases is that patients do not drink our pills.

This is stroke prevention. All of the above has nothing to do with medicine. The best way to reduce bad cholesterol in the blood has been and remains real high-quality fish oil from the muscles of cold-water fish. To whom it is not given - you can even drink a bucket of Cerebrolysin, nothing will change. In the war on smoking, all means are good.

Why do people who quit smoking gain weight? They say: "My metabolism is changing." I drank regularly for two weeks, went to donate blood, but there are no changes. Various patients come to me, ranging from young healthy people (anxious hypochondriacs) to very serious patients (with severe heart failure), and each patient asks: “Doctor, tell me, what if I go quickly and my heart stops?” And seriously ill patients with heart failure also ask: "Doctor, can I move"? The answer is always: "You can!" There is not a single condition in which it would be impossible to move (except for some fractures). High cholesterol is just one of several risk factors for heart disease. You can't do that.

Cardiomagnyl and garlic tablets (video on the topic)

They say to me: “Then what can you offer instead?” Firstly, I can’t offer anything instead of droppers, you don’t need to drip anything. You may experience side effects from taking medications.

Cholesterol is not the only cause of atherosclerosis, but it is undoubtedly the building block of atherosclerotic plaque. Moreover, the younger the patient, the more likely it is that I will write to him "Does not need treatment." Other risk factors

Other risk factors for coronary artery disease and heart attack include high homocysteine ​​levels, obesity, sedentary lifestyle, menopause and the estrogen decline that follows, and metabolic syndrome. But leeches thin the blood, because there is an active substance hirudin there. "Giruda" is a leech. By the way, how do normal people treat a cold? There is a symptom - I take pills, the symptom has passed - that's it, I don't drink pills. And then my mother does not have a choice: to drink or not to drink Atoris. Medical preparations– are convenient in use. These drugs are in principle mandatory, for example, in diabetics with kidney disease, even in renal insufficiency. This is a very hard, rigid, very complex complex, which is coated on top with calcium. This group will especially benefit from reading this article.

It is necessary either to go to a commercial laboratory, or to get into some kind of research. Because on the one hand, I remove inflammation, and on the other hand, the patient adds this inflammation, and it turns out minus plus plus. Decent countries have their own professional medical associations that do their job. Why lose weight? The second book is called Heart and Vascular Health. The floor is already dirty, it needs to be washed again. Yes, it was very social, but there was no special medical component, and there were no special technologies, and there were no special medicines. Have you started to get sick less acute respiratory infections?

There is not a single drug that really treats ARI. What about means of communication? I used to leave the house, and that's it - happiness has come, no one will find you, there is no phone in your pocket. Look, those who quit smoking always have seeds, lollipops, cookies at hand. This is completely serious, this is not a joke. Because Mildronate is made from heptyl (it's rocket fuel). Then the question arises: maybe a placebo is also good? If this helps an 88-year-old patient who is addicted to all this, then so be it, let's not take away the last toy.

It is necessary to understand and accept a simple and important thing: Even an absolutely “herbivore” person, who saw meat only in a children's book in the picture, can have a very high cholesterol level. The main thing is not to draw into it those who are not hooked on it yet.” In the comments, of course, they again began to write that “she is fulfilling the order of the health department to close hospitals.” We must have partnership, collegiate relations. Yes, part of it is genetics. All our diseases require constant treatment. Substitution therapy: who does not have enough of his own brain, we can transplant a pig, in all seriousness. You can quit smoking.

Unemployment appeared, a person became more economically vulnerable, social security decreased, confidence in the future disappeared. In all other cases, there are no courses. Is it possible to stop drinking statins Megapolien these are capsules with golden oil without an unpleasant odor at all. On the one hand, I understand that, according to all world recommendations, the only way to treat it is to stop smoking. You will need to have periodic blood tests to check your liver function. In order to make a decision to use statins, it is important to determine your risk for coronary artery disease and heart attack. How much I have left, so much left.

We analyzed the number of publications, which in Denmark are all collected in electronic form, and saw that the more such publications were in the media, the more patients were who, under their influence, actually stopped taking statins, as a result of which there was an increase in the number of heart attacks and, accordingly, cardiovascular mortality. So I have no conflict of interest today. Don't get sick everyone. Nootropil in huge doses is used for certain types of epilepsy, it does not add the amount of mind. Li Ming | 06/11/16, 11:49 am Can I take omega while taking statinsShould I take statins to treat high cholesterol? Lowering cholesterol will help you prevent heart attack or stroke. My father died when I was at school, my aunt died when I was at the institute. Risk factors are mostly lifestyle factors. Photo: Ivan Jabir, Anna Danilova

Video: Viktor AromshtamThe educational lecture hall of the Orthodoxy and the World portal has been operating since the beginning of 2014. Sometimes they remember about, in medical terms, cognitive impairment, they say that supposedly statins increase the risk of developing dementia (dementia). But this is social assistance, this is not medicine. If you eat so much and think that it is not enough, let it be N, and you need N-1 from your "little" or even less. This pattern applies to absolutely all of our diseases. I really do not want to take drugs that do not affect the quality of life. There has been a lot of clinical research on omega-3s, and it seems that nothing good has come of it.

That's for sure! Think carefully about what is more important to you: your health or the material well-being of pharmacists? Problem with cholesterol? Be surveyed, first of all the Liver! Be healthy and do not trust 100% doctors. Therefore, many mistakenly think that I smoke.

The same is true here. Cerebrolysin - pork, Actovegin - beef. The birth of a child, the birth of a grandson is a positive motivation. Smoking is a very powerful risk factor. Suddenly, instantly, this remaining lumen of the vessel closes. We don't really promise anything more. We used to think that the house is something good. Traffic.

We looked for tumors of the adrenal glands, kidney diseases. We then believed that hypertension is a disease of grandparents, people of the second half of life. I was taught that hypertension develops in women after fifty. The patient says: "Yes, yes, I will sit, of course." Now the Finns, despite their polar night, despite their severe northern climate, are ahead of all Europe in terms of life expectancy. Can cardiologists reduce mortality? First of all, let's answer the most important question: why do cardiologists treat their patients? Oddly enough, when patients come to me and say: “I have heart failure”, “My heart hurts”, “My head hurts”, I don’t immediately think about how to make sure that there is no interruptions, so that the heart does not hurt, the first thought is always: how to make a person live longer. He had a traumatic situation, so maybe there was no true hypertension. Any way to support normal level cholesterol - to someone by a non-drug method, to someone with medicines.

After all, it is impossible to brush your teeth in courses, wash your hands in courses. Someone says that drugs do not affect well-being. But an excess of cholesterol in the blood increases the chances of getting a heart attack or stroke.

These side effects occur when taking diuretics and a lack of potassium and magnesium in the blood. And if there is a symptomatic plaque that, say, causes angina pectoris, then aspirin should be taken. And there are special highly sensitive kits that show the presence of this particular inflammation. Therefore, in primary prevention, just for hypertension, just healthy person just in case, aspirin is not prescribed. Statins reduce triglyceride levels by 7-30%. As for omega-3 polyunsaturated fatty amino acids, they have been studied very well. This is perhaps the only example when the drug is used in a course. We are talking about prevention, and I repeat: it is impossible to take courses in prevention. It always surprises me: how to drink vodka - no one cares what will happen to the liver, but as soon as you prescribe a statin: “What will happen to my liver?” Yes, nothing will happen. Swan, crayfish and pike.

You can't live without bread, you can't live without water, but you can live without cigarettes." It is a fact. I never had any health issues until 2011 when I started taking statins to lower my cholesterol, which went up to 12.1. We also met the question of whether it is possible to independently refuse to take Atoris if an elderly person experiences side effects in the form of dizziness, weaknesses and sleep disorders. But we do not promise immortality. After all, after reading your messages, a person will stop drinking a vital drug, which subsequently leads to sad events. How do you imagine “cleansing vessels”? It is impossible to dissolve, dissolve the plaque with something.

You brush your teeth every day, it doesn't bother you. Everyone was given instructions. This is some kind of “fuflomycin”, some kind of “improver”. Once again I say that you don’t need a cold antiviral drugs It's all money thrown away.

Can you imagine how all this was implemented in twenty years?! And, indeed, during this time in Finland radically changed the structure of mortality and morbidity. Crushing and dissolving are two different things. Now about cholesterol. So here it is cardiovascular disease, diabetes mellitus, bronchial asthma, oncological diseases- everything that forms the basis of morbidity and mortality - basically 50% have a hereditary predisposition. With this slide, I have to announce to you who I am, at whose expense the banquet is and promise that I will not advertise any drugs (I definitely won’t!). Among the lecturers are teachers of spiritual and secular universities, scientists and popularizers of science.

Look for this phrase in search engines. Can I stop brushing my teeth? Of course it is possible. This is either aspirin or the so-called anticoagulants. We know that in developed countries the main cause of death is cardiovascular and oncological diseases. The goal of treating a patient who has had a stroke is not to eliminate the residual effects of a stroke, it is impossible to eliminate them. In Finland, a completely unique project "North Karelia" was implemented. For some reason, no group of drugs is surrounded by as many prejudices as cholesterol-lowering drugs.

On the other hand, I understand that now I will tell him, a 75-year-old man who smokes all his life, that he needs to quit smoking, and he will tell me: “What are you, doctor, I have been smoking for so many years. And this is my fault, I didn’t explain that you need to take medication not to bring down the pressure, Since you already have this disease, it will not go anywhere. There have been attempts, slightly far-fetched, to use Omega-3 for rhythm disturbances. Sometimes in popular science articles they write: "A high dose of a statin reduces the size of the plaque." Reasons not to take statinsYour LDL is above 190 mg/dL. It is often believed that if cholesterol is high, then you need to go on a diet. I am a frank person, I say: “Do you lift your legs yourself or sit in the front row and show how to do it with your finger?” She says: "Most likely the second" ... She had severe hypertension. I drank m-c: cholesterol is normal, and stopped taking it, but endless problems began ... I heard that. if you start taking statins, you can no longer quit and you have to take them for life.

In patients with rheumatoid arthritis, atherosclerosis occurs one and a half times more often. And I drink constantly. But in the situation you described, there could be an overdiagnosis of hypertension. Let's discuss what a dropper is. Statins act at the earliest stage of cholesterol synthesis, putting the body in a difficult position. Ethyl alcohol is practically pure cholesterol. Aspirin is needed when there is already a disease: coronary heart disease, cerebrovascular disease or atherosclerosis of the vessels of the legs.” And the progression of atherosclerosis will occur much faster.

Such a person can sit with us now, he can read this text at this moment and be completely unaware that he has such a plaque in his vessel. Yes, daily intake. Everything has its evidence. A million drugs. As a result of atherosclerosis, there is a general aging of the body (since the organs receive less nutrition). Michele 9:54 am. It is about these 40% that we will talk today. They began to analyze, to find out what was the matter.

If a person has had a heart attack or stroke, he must take drugs constantly, because the risk of relapse is enormous. But it is customary to dose drugs, but how much hirudin is in this particular leech, and in this one? How to dose them? Therefore, the active substance was isolated, purified, synthesized, and a drug, an anticoagulant, was obtained. So far, not one patient has given reasons to worry. But what actually affects life expectancy? You know that 2015 is the year of the fight against cardiovascular disease. Brush your teeth for a month, and do not brush for a month so that the enamel does not wear off. When young people complain about pressure, we say that it can be treated non-pharmacologically: weight loss, salt restriction (sodium pulls water on itself, and fluid retention is one of the mechanisms for increasing pressure). Question: Is it possible to increase the lumen of blood vessels?

Are there cleaning products? vessels?Answer: Medically, unfortunately, it is impossible to do this. When they say that Soviet medicine was good, this is a delusion. The main side effect of cholesterol-lowering drugs is life extension. When we tell students about risk factors, we so carelessly, by the way, mention “psycho-emotional overstrain”. Here's a man life cycle which is that he gets out of bed in the morning, washes, goes to the kitchen, has breakfast, goes down the elevator, gets into the car, arrives at the office, sits in the office on a chair, goes to the dining room, returns to the office and further through the car , kitchen, bath back to bed. Calls I left the office for two minutes, left the phone on charge, returned - five missed calls. But medicine, our medicines, our pills, our operations account for less than 10% (maybe five, maybe three). Literature on the fight against alcoholism.

Together we make up one team that solves the problems of preventing and treating a disease or condition. This is both true and false at the same time. - Pressure is a bit different from a disease that can be brought into stable remission, unlike, for example, an ulcer, bronchial asthma, where sometimes this can happen if treated well. What to do if highly sensitive CRP is positive? This is more difficult. This is the foundation.

Someone reacts calmly, someone explodes on every occasion. When patients from a neurologist come to me after treatment with Cavinton with atrial fibrillation, I begin to grind my teeth. Mexidol is one of succinic acid, a purely Russian thing, there are no proper clinical studies. Pressure is a separate risk factor. Lecture by doctor Anton Rodionov (+video)Anton Rodionov - cardiologist-therapist, candidate of medical sciences, associate professor of the Department of Faculty Therapy, PMSMU IM. You have two or more risk factors for coronary artery disease or at least serious illness. After all, it is impossible to tell everything in 12-15 minutes of admission. Each drug has its own period of action.

I prepared this presentation for the sake of just one slide (although I don’t really need it today, it’s much more interesting just to talk). Moreover, the younger the person, the more likely it is that he needs to be treated without medication. No money. If I take off the prosthesis, then I will limp again.

Those. But many people remember better than me, especially those who were connected with medicine: if a person fell ill and needed a serious drug, then a search began through familiar diplomats how to bring this drug from abroad. The doctor says: "You need to go on a diet." A person with a smoking experience of about seventy years, who smoked since childhood, smoked a lot, really quit smoking. Well, it will stink from the mouth, well, caries will develop. The placebo effect in injections is much better than the placebo effect in pills, this is known. But we have algorithms for how to deal with this: we need to change drugs, we need to use minimum doses. They only work well for the kidneys.

Many drugs are based on the same active substances that were once known. I say: "Wait, we'll do the monitoring first, most likely you won't need any." Everything was clear and understandable there. literally three minutes I talked to him, I listened to him, he had a severe chronic obstructive pulmonary disease. It can be said differently. Next, we will discuss Actovegin, Cerebrolysin, Cortexin, beloved by everyone. The medicine works 24 hours, one action has ended, the second has begun.

Question: Do I need to take something constantly from medications in order to prevent a recurrence of a stroke? Answer: Of course. In underdeveloped countries, the main causes of death are infectious diseases, injuries and accidents, and infant mortality. It is packaged in a capsule so that it is not so disgusting. As long as a person moves, he lives. Why did they refuse, for example, nitrates? Nitrates are now practically not used in medicine, in cardiology. It is really impossible to make a 20% stenosis out of an 80% stenosis. For example, when cinchona (cinchona bark) was used to treat malaria, it was noticed that those who were treated with cinchona for malaria had a heartbeat.

There are special electronic feeders, pillboxes designed for a week, buy these. Consider the following information when you make your decision. Traditionally, there should be a second slide, which is called “Conflict of Interest”. If the lining of the vessels (endothelium) is damaged, cholesterol and many other elements penetrate there, and this plaque forms. Even the maximum dose of statins can reduce this plaque by fractions of millimeters due to its compaction and stabilize it. Is it possible to stop drinking statins3 / 5 based on 707 voters (60%)

But don't even think about the taste! There are such questions for penny counterparts. What increases my chances of coronary artery disease, heart attack, or stroke?

You are at particular risk if: You are a man over 45 or a woman over 55. Of course, than more people smokes, the greater the risk that this plaque will develop rather quickly. We simply decided to write in a small brochure everything that the doctor cannot tell the patient during the appointment. Literature on the fight against alcoholismI want to stop drinking and smoking. We really live in some crazy, absolutely non-physiological information space. In fairness, of course, we must admit that a lot of useful things have been done within the framework of the latest national projects. Last stage alcoholism is a sign of alcohol, but my wife has coded from alcoholism in Minsk, prices ranging from beer to simple worker-peasant vodka. Actovegin is a squeeze from the blood of young calves, beef.

The problem is that cholesterol is synthesized in the body. And everyone needs to move. This is a brilliant development of a Latvian scientist, professor, who simultaneously solved the problem of creating another drip soother and eliminating rocket fuel in Latvia. When deciding to use statins other than medical advice, you should also rely on your personal feelings. All of our blood pressure medications must be taken every day. And what, exactly, is the difference? Brushing your teeth is the prevention of caries.

Let's start with the fact that a dropper is just a jar with 200 milliliters of saline, in which some kind of drug is added. If someone invented this, he would win a Nobel Prize, because the economic losses from ARI all over the planet are enormous. There is such a thing as aerobic exercise. Among the risk factors, there are many that can and should be influenced non-pharmacologically. In all other situations, you need to quit smoking. Summing up, I want to say that medicine does not solve all health problems. Cholesterol is synthesized from active acetate in the body in 22 stages. Irina 01/03/2012 at 16:39 Link

Can I stop the statin? Yes, you certainly may. This is a war of life and death. I took it for two months." If you need to change your diet, reduce the amount of carbohydrates and fats, then this must be done constantly, and not according to the principle of “sit and then get up”. What else is related to the risk factors - the blocks of this foundation? Arterial hypertension, increased cholesterol levels, excess sugar (hyperglycemia or diabetes mellitus) and smoking. undoubtedly.

Cholesterol can be formed from ethyl alcohol without any additional accompanying substances. Many patients report that Atoris works much more effectively when they follow a low-fat diet and increase motor activity. Special mention must be made of Mildronate. I will not talk about smoking for a long time. In the 1970s, the Finns noticed that they had a very high mortality rate from cardiovascular diseases. At the same time, they both say that they eat very little. This is just the borderline between dietary supplements and drugs. Video recordings and texts of all lectures are published on the website. But here the question arises: why did mother nature arrange us this way? Such high cholesterol is that a mistake of nature?

No, this is not a mistake of nature. My aunt left a husband who is still alive, and he is older than her, he is now eighty years old. And even then, when hypotension occurs on the background of treatment, when the patient receiving drugs, the pressure drops below 110-100 millimeters, then this is also a problem. Who was prescribed statins, then the addresses consist of peptides and can be polyunsaturated fatty acids (omega-3,)) since saturated even fatty acids can eventually turn into the same cholesterol, all alcoholic beverages, if banned, they receive information about Since she stopped taking statin drugs, it is not eggs that should be banned, and after a few years, memory problems arose.

But, unfortunately, it can be a negative motivation - an illness, the first heart attack. And then I imagined that the disease also wants to live, and it wants to build a house for itself. You have smoked in the last 30 days. We are talking about the "method" of treatment, which is unfortunately very often used in relation to our patients, especially elderly patients - these are the so-called vascular cleansing drips. All these cerebrolysins and other nonsense absolutely do not work, recovery does not depend on them in any way.

Thus, these are drugs that do not affect the quality of life at all, do not affect the symptoms, but increase life expectancy. But the fact is that we really need very little cholesterol. Yes, now he is eighty years old, he really has cognitive impairments, impaired short memory, as happens at that age. The first book in the series is dedicated to hypertension. “How to live without a heart attack and a stroke” is actually the book “School of Hypertension”, it had such a working title.

My colleague, with whom we read a lot together, said very well: “These droppers are like smoking. The fifth book "Medicines" is devoted, in particular, to the treatment of acute respiratory infections. If you look at the scale of the globe, then it is round, and if you level the summer cottage, then it is quite flat. And people shift this logic to our drugs. What is the point of taking pills if they do not affect the blood in any way? The course of treatment with statins is 12 weeks.

When a husband and wife come, you can immediately see: she loves to cook, he loves to eat. And here is the place in the vessel for which I go to work every day. Because stone-dissolving drugs are very toxic, with very large side effects and a high relapse rate. All of these drugs are actually drugs with an unproven mechanism of action. It is called highly sensitive C-reactive protein. Cortisol, cortisone a, aldosterone, female sex hormones estrogen and progesterone, male sex hormone testosterone, and is also involved in the functioning of nerve cells. He really quit smoking. Not even statins can do that. All this will happen because in this place the tire has torn, and the body has reacted: “Here is damage!” Platelets arrive at the site of injury, and a complex cascade of thrombus formation is triggered.

Hypotension is not a disease. This topic has been actively studied, and in general they agreed that statins are the best way to reduce CRP levels. Semen 11.02.2012 at 19:59 LinkAndroid People, do not take statins, they destroy the liver! Although many doctors consider these drugs to be relatively safe, there are already studies that prove their harmful effects!

My father took Atoris for a long time, as a result he died of cirrhosis of the liver. It is necessary to eat less. But I say again: this does not mean that they should be given to everyone from the cradle.

Snacks at work, tea. Mildronate is produced by chemical conversion of heptyl. The same is true here. I answer: “What do you mean - do not treat? Healing is a process." “But they don’t heal!” Tanakan to the same place, Ginkgo Biloba is a dietary supplement of pure water, it is not registered anywhere as a drug. Everything that I will tell you today, I will tell you as a cardiologist, as an assistant professor at the First Moscow State Medical University, as a member European society cardiologists, the Russian Society of Cardiology and so on. Cholesterol-lowering drugs

Now let's talk about one of the most controversial issues from the patient's point of view about cholesterol-lowering preparations. which many of you know firsthand about "statins" drugs that you are prescribed to lower cholesterol, and you kick them in every possible way. Are there other reasons why you want to take cholesterol-lowering drugs?

Alexander Myasnikov. Ask a doctor. (video on the topic)

You say: “What if someone calls me?” It is very difficult to influence stress, and this is a very serious factor. You have high blood pressure (140/90 mmHg or higher) or are taking medication for high blood pressure. Everything, put away the phone and went in circles around the house to cut. With regard to Atoris, there were no recommendations for the duration of use. Here we have such an audience, in which, I think, no one smokes, but, nevertheless, we work with you all over the country, so this issue is worth discussing.

High cholesterol is a mistake of nature? Diet is still tracing paper from English, diet means a little different, it is a way of eating. Is it hard to lose weight or is it easy? On the one hand, during the Leningrad blockade there were no fat people, there were no fat people in the concentration camps, because they ate very little and moved a lot. Start simple: take a small plate or saucer like a one-serve smorgasbord, that's your one go. Fish oil is vitamin D, which was used even under King Pea to prevent rickets.

She did blood biochemistry, the tests were not very good, they prescribed Atoris. Mildronate is a separate song. In this case, we are talking about the Finnish province of North Karelia. Here they are, the four corners: hypertension, cholesterol, smoking and obesity with a sedentary lifestyle. You know, there are tests for “rheumatic tests”: rheumatoid factor, antibodies to streptococcus and CRP. We cannot predict recovery. Today I brought here a set of my books, then I will present them to our organizers.

I am used to communicating by e-mail and have published my e-mail address in my books, and many write to me. We often have a doctor and a patient perceive each other as antagonists, this is completely abnormal. When Patients Don't Treat The next thing to discuss, and which is undoubtedly a huge problem all over the world, is adherence to treatment, that is, adherence to our recommendations. For twenty-five years, systematic work with the population in the media continued. It is mainly devoted to how to be treated without drugs.

This is what actually affects life expectancy, and not our medical component at all. Honestly, I don’t give a damn about the capital’s health department, I don’t obey him. But what do you think, by what percentage does medicine affect life expectancy? Approximately five percent, according to optimistic estimates - ten, but no more. With the combination of high cholesterol and diabetes, vision is lost and severe damage to the arteries in the legs occurs, leading to amputation. I just calculated: we have about forty molecules on the market just to reduce pressure, and the number of drugs is several hundred. If they figured out how to clean the vessels without surgery, then there would be not a Nobel Prize, but a super-Nobel Prize.

Then I called the company and talked to an employee who admitted that it was about a similar side effect of alcoholism, idiocy, cableism, the effect of Crestor, it was included in the instructions, but not for consumers, alcoholism is folk but for doctors, and very ambiguous. What to do?JIa3ypb 03/07/2012 at 04:41 LinkSemen I am a cardiologist by training, and many patients, I think, were saved from repeated coronary events by Atoris. In the face of a shortage of funding, this social component of medical care is cut off, in fact, not a medical one.

Now all phones are smartphones, they have a built-in pedometer. An analysis of the reviews shows that Atoris, being an effective means for lowering blood cholesterol levels, at the same time requires mandatory medical supervision over the course of treatment. A woman of about fifty came, she was recommended to me as a dance teacher. Again, this trinity: hypertensive drugs that lower cholesterol and antithrombotics. How was it before? The patient comes to the doctor. If it was an atherothrombotic stroke - Plavix or aspirin, if heart rhythm disturbances are observed - anticoagulants that are taken constantly. The only patients for whom we do not recommend quitting are patients who have less than six months to live. I can offer those patients who really need, who have cardiovascular diseases, to treat them.

Therefore, body weight is such a swing between the calories that we eat and the calories that we spend. The second is cholesterol. At Atoris, more than 50 thousand patients have already been examined and the duration is on average from 4 to 6 years.

Salicylic acid is found in raspberries, which is why raspberries are said to have antipyretic properties. Just imagine: the floors were washed, the floor was clean, and then one person in dirty boots walked along it - and that’s it, it doesn’t matter anymore, one person walked or fifteen. Basically, these drugs can be divided into three groups.

But once added additional factors risk, this is where the construction of the disease begins. After taking Atoris for 2 months, all indicators are normal. This is only from hypertension, and there is also arrhythmia, there is heart failure. Washing your hands and brushing your teeth is a preventive measure. And a salad for lunch. I can talk for five years on TV, on the Internet, in newspapers, in magazines, with Myasnikov, without Myasnikov, that they should be accepted!

But no! One publication somewhere about the fact that, it turns out, statins are poison, and cholesterol is good, is enough, as everyone immediately forgets about everything that we have been telling them for five years, and believe this publication. Therefore, before writing, understand the etiology of the occurrence of side effects. Also a very boring, dreary word. Remember when I said that smoking causes inflammation? So even one cigarette a week already causes inflammation. For example, to that young man, who came to me today, has already been prescribed two drugs, but he did not take them, however. It is possible and necessary. Our task is for it to stabilize, so that it does not grow, so that there is no gap.

Lust for life grows stronger with age. This is a bit of a rough analogy. If the patient does not understand what is happening to him, then, of course, he will not be treated. The appearance of leg cramps is sometimes associated with a combination of atorvastatins and other cardiac agents. In fact, you understand that he will not sit on any diet. Statins have nothing to do with it, they said.

I am not afraid to speak the truth and I think that I am not pouring water on anyone's mill. The patient writes the following: “Hello, dear Anton Vladimirovich! A pensioner is writing to you, I am seventy-five years old, but I really want to live. Another study found that statins increase the risk of cataracts, to which my colleague, a lipidologist-cardiologist, says: “Listen, do you want your grandfather to lie in a coffin, but with clear transparent eyes, or for him to still live, but competed for a cataract? We need to understand what we are risking.

Patient to me: “I swear, in the morning only a sandwich. Indeed, there are people with high cholesterol, who do not have atherosclerosis. Everyone writes some kind of program. If someone tells you something or gives a lecture, then the second slide should look like this. I recently had a situation. But for patients with atrial fibrillation (and this is, of course, a disease) well