Galavit - mechanism of action, indications, benefits. Analogues of Galavit: alternative help to immunity and protection against inflammation

The wide variety of diseases that can affect a person during his life requires the use of properly selected drugs. Among medical preparations play an important role in the treatment of diseases immunomodulators. Although there are quite a lot of them today in pharmacies, not all are suitable for the treatment of specific diseases. There is a drug on the pharmacy market called "Galavit", the uniqueness of which lies in its double effect- when applied, it simultaneously has an immunomodulatory and anti-inflammatory effect.

This drug is offered in several pharmacological forms of release, among which you can find exactly those that are suitable for patients of any age. Galavit has been registered as a drug in our country for more than 15 years. During this time, not only specialists, but also patients managed to get acquainted with him. And all of them only speak positively about this medication.

This medicine has been used in many areas of medicine - neurology, dentistry, oncology, surgery, gynecology, etc. Today, you can buy the Galavit drug not only in a regular pharmacy, but also via the Internet.

Composition and action of the drug

chief active ingredient as part of the drug "Galavit" is aminodihydrophthalazinedione sodium. It's about about a synthetically produced compound that provides the drug with an immunomodulatory and anti-inflammatory effect. The mechanism of action of the drug is directly related to the following properties:

The withdrawal of the drug is carried out mainly through the kidneys. The achieved therapeutic effect after taking the medicine lasts up to 3 days. The drug can act as an ingredient in complex therapy many diseases, the development of which is accompanied by a weakening immune system. Doctors can also prescribe it as prophylactic to eliminate chronic inflammatory processes to thereby prolong periods of remission.

Indications

This drug, like any other medication, has its own indications for use, which depend on the dosage and form of release. This medicine is prescribed to patients as an immunomodulator and anti-inflammatory agent in the treatment of a wide variety of diseases.

A preparation in the form of suppositories, about which there are many positive feedback, is indicated for use in children over 12 years of age and adults in the treatment of the following diseases:

For children aged 6 to 12 years, the medicine is prescribed for the following conditions:

as an integral component of the complex therapy of purulent-surgical pathology - peritonitis, appendicitis, osteomyelitis, etc.;
in the treatment of diseases respiratory system viral and bacterial nature and diseases of ENT organs - otitis media, tonsillitis in chronic form, pneumonia and bronchitis;
as a means of treating diseases of the gastrointestinal tract - viral hepatitis, gastric ulcer and duodenum, intestinal infections;
in the treatment of diseases resulting from the penetration of the herpes virus into the body or the virus human papillomas;
to improve well-being due to exposure adverse factors- decreased performance physical fatigue, neuroses and other conditions;
as an operative and means of preventing purulent-septic complications in surgery for urogenital infections;
often "Galavit" is used in dentistry- the drug can help in the treatment of periodontal disease, diseases of the mucous membranes of the mouth and throat.

"Galavit": instructions for the use of candles

Since the drug is offered in pharmacies in different pharmacological forms, the dosage regimen in each case will be different.

In the form of injections

"Galavit" is administered to the patient one injection every 24, 48 or 72 hours. The exact frequency of administration depends on the severity of the disease. To achieve the required therapeutic effect must pass full course, for which it is necessary to make up to 25 injections.

in the form of candles

The drug is prescribed for the treatment of acute respiratory viral infections, pneumonia, sinusitis and bronchitis. The reception scheme involves the introduction of 1 candle rectally once a day for a course of 5 days. If the drug was prescribed for the treatment of other diseases, then one or two suppositories are administered once a day for up to 25 days. It should be remembered that "Galavit" is not a drug for vaginal use.

In the form of tablets

According to the instructions and reviews, the drug can be used by adults and children over 12 years of age. To prevent ARVI and influenza, the medicine should be taken one tablet 2 times a day for a course of 5-10 days. If the drug was prescribed for the treatment of other pathologies, then it is taken 1 tablet 4 times a day for up to 3 weeks.

All these schemes are general, each specific disease requires individual approach choosing the optimal dosage.

If the drug was prescribed to a patient who is already being treated with other drugs, you need to remember the following: as a result of the simultaneous use of Galavit with antibiotics, its single dosage decreases, since the effectiveness of the latter decreases. At the same time, this drug is compatible with all known drugs.

One of the questions that worries many patients who are going to take Galavit medicine is whether it is safe to drink alcohol while taking it? At the moment, experts do not have information about the negative impact of alcohol-containing drinks on Galavit. But at the same time, it must be remembered that alcohol can adversely affect the drug, lowering or enhancing it. therapeutic effect. The same applies to taking along with alcohol and other medicines.

It should also be taken into account that alcohol itself has negative impact on the functioning of the immune system, which is the complete opposite effect that Galavit has. It is for this reason that when treating any disease, patients need to forget about drinking alcohol for a while. This applies even to those cases when the doctor was prescribed for the treatment of candles "Galavit".

Contraindications

One of the main factors that can become a sufficient reason for refusing to prescribe a drug is individual intolerance constituent components drug. If the patient has previously had allergic reactions on certain substances of certain drugs, then before prescribing Galavit, you need to carefully read the instructions. If you notice any side effects after taking the drug, for example, itching, rash, you should immediately stop using it and see a doctor.

Other absolute contraindication to the use of "Galavit" is pregnancy and lactation. Considering that experts did not study the effectiveness and impact of the Galavit drug on the body of women during childbearing and feeding, it is contraindicated to use this drug for them.

Although sometimes the gynecologist may decide to prescribe this drug during pregnancy. He can take such a step in a situation if the young mother was struck by serious illness and she needs immunomodulators. In this case, it should be regularly observed by a specialist. It is forbidden to take Galavit on your own during pregnancy and during breastfeeding. Due to the lack of data on the use of the Galavit drug, suppositories can only be used vaginally by the rectal method.

It is unacceptable to prescribe the drug to children under 6 years of age. This contraindication applies to all available in pharmacies pharmacological forms drug, with the exception of tablets, which is not prescribed to children under 12 years of age. Because the experts did not clinical researches regarding the effect of this drug on patients indicated age groups, it is best not to prescribe Galavit for treatment.

Side effects

Before being released to the pharmacy market, the drug went through many clinical trials, during which he proved to be quite safe drug. And although most patients tolerate it quite well, some may experience allergic reactions. Therefore, people who are prone to developing allergic manifestations It is not recommended to use the drug on your own without prior consultation with a specialist. First of all, this concerns the injection form.

If any side effects were found as a result of the use of the drug, the patient should stop using it and immediately see a doctor.

"Galavit" candles: price

The medicine "Galavit" in the form of suppositories cannot be called accessible to a wide range of patients. In Russian pharmacies, it can be purchased at an average price of 855 rubles.

Galavit is a new generation immunomodulatory drug that has a pronounced anti-inflammatory effect on the body.

Release form and composition

The drug is made in three dosage forms:

Galavit tablets containing 25 mg of sodium aminodihydrophthalazindione, as well as auxiliary components: lactose, starch, talc, sorbitol, calcium stearate, racementol;
Rectal suppositories Galavit containing 50 or 100 mg of the active substance, as well as auxiliary components: witepsol H-15 and witepsol W-35;
Powder for the preparation of Galavit solution containing 50 or 100 mg of active ingredient.

Indications for use

According to the instructions, Galavit is used as part of complex treatment for the correction of immunity in children over 12 years old and adults with the following conditions:

Chronic and acute diseases digestive tract accompanied by diarrhea and intoxication of the body (Crohn's disease, nonspecific colitis, viral hepatitis B and C, infectious diseases of the gastrointestinal tract, liver diseases of a non-viral nature, gastroenteritis);
Ulcerative lesions of the stomach and duodenum;
Acute infectious diseases respiratory tract, including pneumonia and bronchitis;
Post-traumatic osteomyelitis of an infectious nature;
Diseases of the oral cavity of an infectious nature;
Urogenital infectious diseases, including mycoplasmosis, urogenital chlamydia, cytomegalovirus infection;
Adenoma prostate;
Furunculosis, erysipelas;
Inflammatory diseases that developed against the background of secondary immunodeficiency;
Herpetic infection regardless of localization.

Also, the use of Galavit is advisable for the prevention of infectious diseases in postoperative period, in oncology for immunological correction, including breast cancer and lung cancer.

Contraindications

According to the instructions, Galavit is contraindicated in:

Hypersensitivity to the active or auxiliary components of the drug;
Pregnancy and breastfeeding.

Method of application and dosage

The duration of treatment with Galavit and the dosage regimen is determined individually by the attending physician, depending on the type of pathology and the effectiveness of therapy.

Powder Galavit before use should be dissolved in 2 ml of 0.9% sodium chloride or water for injection. Injections are made intramuscularly. At infectious pathologies digestive tract appoint 2-3 injections per day. The initial dose is 0.2 g, subsequently reduced to 0.1 g.

Galavit injections for various kinds infections are prescribed according to the same scheme, however, the duration of treatment is long and is up to 25 injections.

non-communicable diseases of the gastrointestinal tract and genitourinary system are treated by using Galavit for several days, 2 g each, followed by the transition to the use medicinal product at a dose of 1 g every other day. As a rule, the course of treatment consists of 15-25 Galavit injections.

With uterine myoma, as well as to prevent infections in the postoperative period daily dose Galavita is equal to 1 g once a day with a duration of therapy of 5 days, after which the drug is administered at a dose of 1 g every other day for 10 days. At the final stage of therapy, injections are made 1 g once every 2-3 days. General course treatment is 15-25 Galavit injections.

With prostate adenoma, Galavit injections are made at 1 g for 5 days, after which they switch to the use of Galavit at a dose of 1 g once every 2-3 days.

With recurrent furunculosis and herpetic infection the course of treatment with Galavit is 20 injections following scheme: 1 g per day for 10 days, then 1 g every other day.

Chronic inflammatory infections are treated by administering 1 g of Galavit once a day for 5 days, after which they switch to the introduction of 1 g of the drug every other day. The course of treatment is 20 injections. According to the same scheme, vaccination is carried out for the purpose of immunological correction in cancer patients.

Sublingual tablets Galavit take 1 piece 2-4 times a day. The duration of treatment can vary from 5 days to 3 weeks.

Before using Galavit rectal suppositories, empty the intestines. At infectious diseases it is recommended to administer 0.2 g of Galavita divided into two doses. After the disappearance of symptoms, you can switch to the use of 0.1 g per day.

With pathologies of the gastrointestinal tract and the genitourinary system, the course of treatment with the drug is 15-25 suppositories according to the following scheme: the first two days, 0.2 g each, after which they switch to 0.1 g, which is administered once every three days.

For prevention postoperative complications Galavit candles are prescribed according to the following scheme: the first 5 days - 0.1 g per day, then 10 days - 0.1 g once every two days, another 15 days - 0.1 g once every 3 days. In total, the course is equal to 15 Galavita candles.

Side effects

The use of Galavit by patients is well tolerated, side effects do not arise. Occasionally, allergic reactions are possible due to hypersensitivity to the components of the drug.

special instructions

Analogues

An analogue of Galavit containing the same active substance, is Tamerite, which is produced in the form of a powder for the preparation of a solution for injection.

similar pharmacological effects with Galavit provide:

Anaferon;
Vitanam;
Arpeflu;
Arpetolid;
Cycloferon;
Tamiktid;
Ribomunil;
Engystol;
Cytovir;
Imunofan;
Immunal;
Taktivin;
Cytovir;
Methyluracil;
Molixan and others.

Terms and conditions of storage

According to the instructions, Galavit is stored in a dry, dark, cool place out of the reach of children. The shelf life of Galavit in the form of tablets and suppositories is 2 years, powder - 4 years from the date of manufacture.

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Acute inflammatory or chronic diseases in some cases, they require the use of an agent that stimulates the body's immunity. Doctors resort to their help with frequent colds, bronchitis, chronic otitis media, tonsillitis and many other ENT diseases. One of these drugs is Galavit.

The active substance of the drug - sodium salt phthalazine, which has anti-inflammatory and immunomodulatory effects. Their mechanism is based on the ability of this compound to increase the activity of macrophages - special cells that destroy foreign microorganisms. In addition, Galavit:

Able to inhibit the synthesis of inflammatory mediators, such as interleukins.
Reduces the formation of reactive oxygen species, which can damage healthy cells organism.
Stimulates the activity of granulocytes - one of the varieties of leukocytes, which also protect the body from pathogens of infectious diseases.

The complex action of Galavit preparations increases the body's nonspecific resistance to a wide variety of infectious diseases.

To date, Galavit exists in the form of rectal suppositories, powder for solution for injection and sublingual tablets. Indications for use for all three forms of the drug will be the same.

It is prescribed for various inflammatory diseases upper and lower respiratory tract, with infections caused by a virus, flu or a cold. It can be used for both prevention and treatment.

Analogues

An analogue is a drug that contains the same active substance as in Galavit. To date, there is only one closest analogue of Galavit - this is the drug Tamerit.

Tamerite also contains the sodium salt of phthalazine in its composition, therefore it is similar in composition and acts on Galavit. Only there is a drug in a single form - in the form of a powder for preparing a solution for intramuscular injection.

In addition to this drug, there are drugs similar to Galavit in action. That is, they also have immunomodulatory effects, but their composition and dosage form will be different.

Therefore, to talk about what it is complete analogues Galavit candles are not quite right. Several drugs will be similar in action.

Polyoxidonium

Immunomodulatory, anti-inflammatory and antioxidant. Today, pharmaceutical companies produce lozenges, suppositories, injections and drops.

Like candles Galavit, the drug is used to prevent or treat various ENT diseases. However, it works a little differently. Its effect is based on:

Impact on special cells of the immune system - natural killers, neutrophils and macrophages.
Reducing the level of aggressive oxygen and protecting cells from damage.
Blocking the production of inflammatory mediators.
Stimulation of the formation of interferon.

Polyoxidonium can be used in adults and children over three years old. During pregnancy and breastfeeding it can also be prescribed, but only if the benefit significantly outweighs the risk of development negative consequences. Despite the fact that in experiments on animals, the drug did not reveal toxic action per embryo, sufficient clinical experience Polyoxidonium has not yet been used in pregnant women.

Derinat

There are two types of dosage forms: nasal drops and injection solution. In composition, it is the sodium salt of DNA, which is obtained from the milk of sturgeon fish. The drug also affects the immune system, however, in addition to this, it has several additional effects:

Stimulates regeneration processes, therefore it is often prescribed for healing infected wounds, deep burns and trophic ulcers.
Helps to cleanse wounds in gangrenous processes.
Improves the condition of organs and tissues in dystrophies caused by impaired vascular function.

It has the only contraindication for use - intolerance to the components that make up the drug. It can be used in children at any age, while expecting a baby or breastfeeding.

Imunofan

Available in the form of a spray, solution for injection and suppositories. In addition to immunomodulatory properties, it also has detoxifying, hepatoprotective and antioxidant properties. After taking, it is the detoxification effect that develops first, and additionally the drug:

Inhibits the breakdown of the cell wall.
It inhibits the synthesis of arachidonic acid and thereby blocks the production of inflammatory mediators.
Reduces the level of cholesterol in the blood.
It has a beneficial effect on the function of liver cells - hepatocytes, reducing their toxic injury, and not only from viruses and bacteria, but also from drugs.
Activates cellular immunity, mainly due to the effect on phagocytes.

Imunofan can be used in adults and children over two years old. During pregnancy and lactation, the drug is prescribed in exceptional cases.

In the treatment of ENT diseases, it is usually used as additional remedy in case of severe, protracted, chronic infections.

Cycloferon

A drug that exists not only in the form of tablets or solution for injection, but also in the form of liniment for external use. According to the classification, Cycloferon refers to interferon inducers, that is, in the human body it affects the production of its own interferon.

The main mechanism of action of Cycloferon is similar to that of the drugs of the Galavit line, it also increases the activity of macrophages. However, the drug also has a direct antiviral action. That is, it affects not only the immune system, but also the viruses themselves, namely, it partially blocks the reproduction processes and leads to the formation of defective viral particles.

Cycloferon is prescribed for influenza and SARS for adults and children over four years of age. Contraindications for use are pregnancy, lactation and serious illnesses liver.

Imunorix

There is a single version - a solution for oral administration. Affects special cells of the immune system, increasing their activity. In addition, Imunorix increases the production of cytokine proteins, which also play important role in the formation of the body's defense against viruses, bacteria and fungi.

The drug itself is practically not used. Doctors usually include it in their regimens for flu or other viral infections both acute and chronic.

The drug is contraindicated in children under three years of age. As far as pregnancy or breastfeeding is concerned, rare cases Imunorix can be prescribed during such periods.

Despite the fact that the drugs have similar indications, and the effect of their use is similar to that of Galavit candles, it is impossible to replace one remedy with another on your own. Only a doctor can do this.

The closest in action and dosage forms to Galavit candles are only Polyoxidonium and Imunofan, which also exist in candles. As for the rest of the medicines, apart from the main effect from the use of other matches with Galavit, they do not have.

Immunomodulatory and anti-inflammatory drug

Active substance

Aminodihydrophthalazinedione sodium

Release form, composition and packaging

◊ Suppositories rectal from white to white with a yellowish tint, torpedo-shaped, without visible patches on a longitudinal section.

Excipients: witepsol W-35 (glycerides fatty acids) - 575 mg, witepsol H-15 (fatty acid glycerides) - 575 mg.

5 pieces. - cellular contour packings (1) - packs of cardboard.
5 pieces. - cellular contour packings (2) - packs of cardboard.

pharmachologic effect

The mechanism of action is associated with the ability to influence the functional and metabolic activity of macrophages.

In inflammatory diseases, it reversibly (for 6-8 hours) inhibits excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, reactive oxygen species by hyperactivated macrophages, which determine the degree inflammatory reactions, their cyclicity, as well as the severity of intoxication. Normalization functional state macrophages leads to the restoration of the antigen presenting and regulatory functions of macrophages, a decrease in the level of autoaggression.

Stimulates bactericidal activity neutrophilic granulocytes, enhancing phagocytosis and increasing nonspecific resistance body to infectious diseases.

Pharmacokinetics

It is excreted from the body mainly by the kidneys. After rectal application T 1/2 is 40-60 min.

Main pharmacological effects observed for 72 hours.

Indications

Suppositories rectal 100 mg

As an immunomodulating and anti-inflammatory agent in the complex therapy of immunodeficiency conditions in adults and adolescents over 12 years of age:

- infectious intestinal diseases accompanied by intoxication and / or;

- viral hepatitis;

- infectious and inflammatory diseases of the urogenital tract (urethritis of chlamydial and trichomonas etiology, chlamydial, acute and chronic salpingo-oophoritis, endometritis);

- purulent-inflammatory diseases of the pelvic organs;

— postoperative rehabilitation of patients with uterine myoma;

- complications of the postoperative period in women reproductive age;

- chronic recurrent furunculosis, erysipelas;

— asthenic conditions, neurotic and somatoform disorders, decreased physical performance(including athletes);

- Mental, behavioral and post-withdrawal disorders in alcohol and drug addiction;

non-specific prevention and treatment of acute respiratory infections.

Suppositories rectal 50 mg

As an immunomodulating and anti-inflammatory agent in complex therapy in children aged 6-12 years:

- infectious intestinal diseases accompanied by intoxication and / or diarrhea;

- peptic ulcer of the stomach and duodenum;

chronic relapsing diseases caused by herpes virus;

- diseases caused by the human papillomavirus;

- purulent surgical diseases (including burn lesions, recurrent furunculosis, chronic, gangrenous appendicitis with omentitis, peritonitis, purulent pleurisy);

- asthenic conditions, neurotic and somatoform disorders, decreased physical performance;

- postoperative purulent-septic complications and their prevention (including in oncological patients);

– treatment and prevention of urogenital infections of bacterial and viral etiology;

- inflammatory diseases of the mucous membrane of the mouth and throat, periodontal disease;

- frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent SARS, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis);

- prevention of influenza and acute respiratory infections.

Contraindications

- pregnancy;

- lactation period;

— childhood up to 6 years (for suppositories 50 mg);

- individual intolerance.

Dosage

Rectally. The suppository is released from the contour packaging and then injected into the rectum. It is recommended to first empty the intestines.

The dose and duration of the drug depends on the nature, severity and duration of the disease.

Suppositories 100 mg

Adults and teenagers over 12 years old

At acute intestinal infections accompanied by diarrheal syndrome, the initial dose is 2 supp. once, then - 1 supp. 2 times / day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course of 1 supp. with an interval of 72 hours. The course is 20-25 supp.

At in acute period - 2 supp. 1 time / day for 2 days, then - 1 supp. with an interval of 72 hours. The course is 15-25 supp. AT chronic period - within 5 days, 1 supp. 1 time / day, then - 1 supp. after 72 hours. The course is 20 supp.

At viral hepatitis the initial dose is 2 supp. once, then 1 supp. 2 times / day until relief of symptoms of intoxication and inflammation. Subsequent continuation of the course - 1 supp. with an interval of 72 hours. The course is 20-25 supp.

At appoint 1 supp. daily for 5 days, then - 1 supp. every other day for 15 days.

At diseases caused by the human papillomavirus, the drug is prescribed for 5 days, 1 supp. 1 time / day, then - 1 supp. in one day. The course is 20 supp.

At urogenital infections (chlamydial and Trichomonas urethritis, chlamydial prostatitis)- on the 1st day, 1 supp. 2 times / day, then - 1 supp. in one day. The course is 10-15 supp. depending on the severity of the pathological process.

At salpingoophoritis, endometritis in the acute period appoint within 2 days, 2 supp. 1 time / day, then - 1 supp. with an interval of 72 hours. In the chronic period- within 5 days, 1 supp. 1 time / day, then - 1 supp. every 72 hours. The course is 20 supp.

At acute and chronic purulent diseases pelvic organs - in the acute period the drug is prescribed on the 1st day 2 supp. once, then for 3 days, 1 supp. daily, then - 1 supp. every other day for 5 days. Course - 10 supp. In the chronic period the drug is prescribed for 5 days, 1 supp. 1 time / day, then - 1 supp. every 72 hours. The course is 20 supp.

For postoperative rehabilitation patients with uterine myoma and complications of the postoperative period in patients of reproductive age- within 5 days, 1 supp. 1 time / day, then - 1 supp. in one day. Course - 15 supp.

For prescribe before surgery - for 5 days, 1 supp. 1 time / day, after surgery - 1 supp. every other day (5 supp.) and 5 supp. with an interval of 72 hours. severe course diseases, the initial dose of the drug is 2 supp. once or 1 supp. 2 times/day Course - 20 supp.

At chronic recurrent furunculosis, erysipelas- within 5 days, 1 supp. 1 time / day, then - 1 supp. in one day. Course - 20 supp.

At asthenic conditions, neurotic and somatoform disorders, at mental, behavioral and post-withdrawal disorders, in patients with alcohol and drug addiction - within 5 days, 1 supp. daily, then - 1 supp. after 72 hours Course - 15-20 supp.

For - 1 supp. every other day - 5 supp., then - 1 supp. after 72 hours Course - up to 20 supp.

At the initial dose of the drug is 1 supp. daily for 5 days, then - 1 supp. with an interval of 72 hours Course - 15 supp.

For nonspecific prophylaxis and treatment of influenza and acute respiratory infections- 1 supp. 1 time / day Course - 5 days.

Suppositories 50 mg

Children aged 6-12 years

At acute infectious intestinal diseases associated with diarrheal syndrome, the initial dose is 2 supp. once, then 1 supp. 2 times / day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course of 1 supp. with an interval of 72 hours Course - 20 supp.

At peptic ulcer stomach and duodenum in the acute period- in the first 2 days, 2 supp. 1 time / day, then 1 supp. with an interval of 72 hours Course - 15-25 supp. AT chronic period- within 5 days, 1 supp. 1 time / day, then 1 supp. after 72 hours Course - 20 supp.

At chronic relapsing diseases caused by the herpes virus, appoint 1 supp. daily for 5 days, then 1 supp. every other day - 15 supp.

At diseases caused by the human papillomavirus, appoint within 5 days on 1 supp. 1 time / day, then 1 supp. in one day. Course - 20 supp.

At purulent surgical diseases (burn lesions, recurrent furunculus, chronic osteomyelitis, gangrenous appendicitis with omentite, purulent pleurisy) appoint 1 supp. daily for 5 days, then 1 supp. every other day for 10 days.

At asthenic conditions, neurotic and somatoform disorders- within 5 days, 1 supp. daily, then 1 supp. after 72 hours Course - 15 supp.

For increase physical performance- 1 supp. in one day; course - 5 supp.

For prevention and treatment surgical complications in the pre- and postoperative period (including in oncological patients) appoint within 5 days before surgery, 1 supp. 1 time / day, 1 supp. one day after the operation (5 supp.) and 5 supp. - with an interval of 72 hours. In severe cases of the disease, the initial dose is 2 supp. once or 1 supp. 2 times/day Course - 20 supp.

For treatment and prevention of urogenital infections of bacterial and viral etiology the drug is prescribed on the 1st day, 1 supp. 2 times / day, then 1 supp. in one day. Course 10-15 supp. (depending on the severity of the pathological process).

At inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases the initial dose is 1 supp. daily - 5 supp., then 1 supp. with an interval of 72 hours Course - 15 supp.

Among the wide variety of immunomodulating agents on the modern pharmaceutical market, Galavit is distinguished.

it domestic drug, which has been successfully used over the past 15 years in many branches of medicine. special attention deserve suppositories used in gynecology.

On this page you will find all information about Galavit: complete instructions on application to this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Galavit suppositories. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Immunomodulatory drug.

Terms of dispensing from pharmacies

Released without a prescription.

Prices

How much does Galavit cost in the form of candles? average price in pharmacies is at the level of 800 rubles.

Release form and composition

Candles Galavit rectal have a white or yellowish-white hue, torpedo-shaped, no visible inclusions. Sold in blister strip packaging, in cardboard box a pack of 10 suppositories is included.

In one rectal suppositories contains 0.1 g galavita , additional substances.

Pharmacological effect

After the introduction of the suppository into the rectum, there is a rapid (within 20 minutes) absorption of the drug into the systemic circulation. Active substance penetrates everything well. functional fabrics body and acts locally:

normalizes antibody formation, and activates T-cell immunity;
has an indirect effect on the production of endogenous interferons - substances that can fight foreign antigens;
affects the phagocytic activity of neutrophils and macrophages: the ability of immune cells to capture and destroy pathogen cells increases;
produces a reversible blocking of the production of inflammatory markers (cytokines, tumor necrosis factor and others).

The above effects are valid for 68-72 hours after administration. The drug has an average bioavailability (61%). Metabolites of Galavit are excreted mainly through the kidneys.

Indications for use

Galavit is used for prevention and pathogenetic treatment:

Traumatic osteomyelitis;
Inflammatory diseases gastrointestinal tract( and , non-specific ulcerative colitis, etc.);
Inflammatory diseases of the urogenital area (, pyelitis, etc.);
Inflammatory diseases of the urogenital area (salpingitis, vaginitis, etc.);
Ear infections (, dysentery, food poisoning and other diseases accompanied by diarrheal syndrome);
Reduced sexual function, which is based on a violation of microcirculation;
infectious diseases ( various etiologies septic conditions, hepatitis, purulent meningitis);
Bronchopulmonary diseases (, including with,);
Immunodeficiency states, as well as for the correction of immunity in cancer patients in the pre- and postoperative period, receiving radiation and chemotherapy;
Various vascular disorders (diabetic angiopathy, endarteritis and related complications, ischemic angiopathy of various organs);
Chronic inflammatory diseases (including those with allergic and autoimmune components in the pathogenesis - liver damage of various etiologies, scleroderma, endometritis, etc.);
Prevention of postoperative complications.

Contraindications

Contraindications to the use of the drug are hypersensitivity to the constituent substances, pregnancy and lactation.

Use during pregnancy and lactation

Treatment with a woman's drug is contraindicated throughout pregnancy and during breastfeeding.

Instructions for use

The instructions for use indicate that Galavit suppositories are used rectally. The suppository is released from the contour packaging and then injected into the rectum. It is recommended to first empty the intestines. The dose and duration of the drug depends on the nature, severity and duration of the disease.

Suppositories 50 mg are intended for children aged 6-12 years:

To improve physical performance - 1 supp. in one day; course - 5 supp.
With peptic ulcer of the stomach and duodenum in the acute period - in the first 2 days, 2 supp. 1 time / day, then 1 supp. with an interval of 72 hours Course - 15-25 supp. In the chronic period - within 5 days, 1 supp. 1 time / day, then 1 supp. after 72 hours Course - 20 supp.
In acute infectious intestinal diseases accompanied by diarrheal syndrome, the initial dose is 2 supp. once, then 1 supp. 2 times / day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course of 1 supp. with an interval of 72 hours Course - 20 supp.
In chronic recurrent diseases caused by the herpes virus, appoint 1 supp. daily for 5 days, then 1 supp. every other day - 15 supp.
In viral hepatitis, the initial dose is 2 supp. once, then 1 supp. 2 times / day until relief of symptoms of intoxication and inflammation. Subsequent continuation of the course - 1 supp. with an interval of 72 hours Course - 20 supp.
In diseases caused by the human papillomavirus, 1 supp is prescribed for 5 days. 1 time / day, then 1 supp. in one day. Course - 20 supp.
In asthenic conditions, neurotic and somatoform disorders - within 5 days, 1 supp. daily, then 1 supp. after 72 hours Course - 15 supp.
In case of purulent surgical diseases (burn lesions, recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with omentitis, purulent pleurisy), 1 supp is prescribed. daily for 5 days, then 1 supp. every other day for 10 days.
In inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases, the initial dose is 1 supp. daily - 5 supp., then 1 supp. with an interval of 72 hours Course - 15 supp.
For the treatment and prevention of urogenital infections of bacterial and viral etiology, the drug is prescribed on the 1st day, 1 supp. 2 times / day, then 1 supp. in one day. Course 10-15 supp. (depending on the severity of the pathological process).
For the prevention and treatment of surgical complications in the pre- and postoperative period (including in oncological patients), 1 supp is prescribed for 5 days before surgery. 1 time / day, 1 supp. one day after the operation (5 supp.) and 5 supp. - with an interval of 72 hours. In severe cases of the disease, the initial dose is 2 supp. once or 1 supp. 2 times/day Course - 20 supp.
With frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent SARS, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) - 1 supp. daily for 5 days, then 1 supp. every other day for 10 days. Course - 15 supp.
For the prevention of influenza and acute respiratory infections - 1 supp. 1 time / day Course - 5 supp.

Suppositories 100 mg are intended for adults and adolescents over 12 years of age:

To improve physical performance - 1 supp. every other day - 5 supp., then - 1 supp. after 72 hours Course - up to 20 supp.
In chronic recurrent furunculosis, erysipelas - for 5 days, 1 supp. 1 time / day, then - 1 supp. in one day. Course - 20 supp.
With peptic ulcer of the stomach and duodenum in the acute period - 2 supp. 1 time / day for 2 days, then - 1 supp. with an interval of 72 hours. The course is 15-25 supp. In the chronic period - within 5 days, 1 supp. 1 time / day, then - 1 supp. after 72 hours. The course is 20 supp.
In acute intestinal infections accompanied by diarrheal syndrome, the initial dose is 2 supp. once, then - 1 supp. 2 times / day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course of 1 supp. with an interval of 72 hours. The course is 20-25 supp.
In viral hepatitis, the initial dose is 2 supp. once, then 1 supp. 2 times / day until relief of symptoms of intoxication and inflammation. Subsequent continuation of the course - 1 supp. with an interval of 72 hours. The course is 20-25 supp.
In diseases caused by the human papillomavirus, the drug is prescribed for 5 days, 1 supp. 1 time / day, then - 1 supp. in one day. The course is 20 supp.
In chronic recurrent diseases caused by the herpes virus, appoint 1 supp. daily for 5 days, then - 1 supp. every other day for 15 days.
With salpingoophoritis, endometritis in the acute period, 2 supp are prescribed for 2 days. 1 time / day, then - 1 supp. with an interval of 72 hours. In the chronic period - for 5 days, 1 supp. 1 time / day, then - 1 supp. every 72 hours. The course is 20 supp.
In acute and chronic purulent diseases of the pelvic organs - in the acute period, the drug is prescribed on the 1st day 2 supp. once, then for 3 days, 1 supp. daily, then - 1 supp. every other day for 5 days. Course - 10 supp. In the chronic period, the drug is prescribed for 5 days, 1 supp. 1 time / day, then - 1 supp. every 72 hours. The course is 20 supp.
For postoperative rehabilitation of patients with uterine myoma and complications of the postoperative period in patients of reproductive age - within 5 days, 1 supp. 1 time / day, then - 1 supp. in one day. Course - 15 supp.
For the prevention and treatment of surgical complications in the pre- and postoperative period (including in oncological patients), it is prescribed before surgery - for 5 days, 1 supp. 1 time / day, after surgery - 1 supp. every other day (5 supp.) and 5 supp. with an interval of 72 hours. In severe cases of the disease, the initial dose of the drug is 2 supp. once or 1 supp. 2 times/day Course - 20 supp.
With asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and post-abstinence disorders, in patients with alcohol and drug addiction - within 5 days, 1 supp. daily, then - 1 supp. after 72 hours Course - 15-20 supp.
In inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases, the initial dose of the drug is 1 supp. daily for 5 days, then - 1 supp. with an interval of 72 hours Course - 15 supp.
With urogenital infections (chlamydial and trichomonas urethritis, chlamydial prostatitis) - on the 1st day, 1 supp. 2 times / day, then - 1 supp. in one day. The course is 10-15 supp. depending on the severity of the pathological process.
For non-specific prevention and treatment of influenza and acute respiratory infections - 1 supp. 1 time / day The course is 5 days.

Side effects

Galavit rarely has a negative effect on the body, in less than 0.1% of cases. To side effects allergic reactions from the mucous membranes and skin can be attributed: itching, redness, rash, urticaria.

Overdose

There are no data on drug overdose.

drug interaction

When this drug is used concomitantly with drugs antibacterial action it is possible to reduce the dosage of the latter.

The drug "Galavit" and alcohol can be combined, but it is better not to abuse alcohol during treatment.

Information about interactions with other drugs on this moment no.