Instructions for use of chlorhexidine bigluconate solution. Indications for the use of chlorhexidine. Chlorhexidine is active against

Name:

Chlorhexidine bigluconate (Chlorhexidine bigluconate)

Pharmachologic effect:

An aqueous solution of chlorhexidine bigluconate is local antiseptic, with predominantly bactericidal action. Chlorhexidine bigluconate by chemical structure close to bigumal and is a dichloride derivative of biguanide. The mechanism of action is based on its ability to change properties cell membrane microorganism. After the dissociation of chlorhexidine salts, the formed cations react with the shells of bacteria that have a negative charge. At the same time, the lipophilic groups of the drug contribute to the disaggregation of the lipoprotein membrane of bacteria, as a result of which there is a violation of the osmotic balance and the loss of potassium and phosphorus from the bacterial cell. Under the action of the drug, the cytoplasmic membrane of the bacterium is destroyed and its osmotic balance is disturbed, as a result of which the death of the bacterium occurs.

The drug is effective against strains of such microorganisms: Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia spp., Bacteroides fragilis, Treponema pallidum, Gardnerella vaginalis. In addition, chlorhexidine bigluconate is active against Ureaplasma spp. and moderately active against some strains of Proteus spp. and Pseudomonas spp.

Viruses (except for the herpes virus), as well as fungal spores, are resistant to the drug.

The drug is not absorbed into the systemic circulation when topical application and has no systemic effect.

After treatment of the skin (including the skin of the hands), a certain amount of the drug remains on the skin, so chlorhexidine bigluconate has a long antibacterial effect and can be used for treatment operating field and hands of the surgeon.

The antimicrobial activity of the drug is preserved in the presence of pus, blood and other physiological fluids, however, it is worth noting that in this case its effectiveness is somewhat reduced.

Indications for use:

The drug is used to treat and prevent various diseases caused by microorganisms sensitive to the action of chlorhexidine. Indications for the use of the drug depend on its initial concentration.

Solution of chlorhexidine bigluconate 0.05%, 0.1% and 0.2%:

Prevention of infectious diseases after surgical interventions, including in dental and ENT practice. In dentistry, the drug is also used for the treatment of removable dentures.

Skin treatment before and after surgical intervention for the prevention of infection in urology, surgery, as well as obstetric and gynecological practice.

Disinfection of the skin and mucous membranes before carrying out diagnostic and treatment procedures in gynecological practice.

The drug is also used to treat various skin diseases of bacterial and fungal etiology, as well as purulent wounds, and lesions of the mucous membranes, which are caused by microorganisms sensitive to the action of the drug (including stomatitis, periodontitis, gingivitis and aphthae).

In addition, the drug is used after unprotected intercourse for the prevention of sexually transmitted diseases, including chlamydia, genital herpes, syphilis, trichomoniasis and gonorrhea. As well as the treatment of damaged skin in order to prevent infection.

Solution of chlorhexidine bigluconate 0.5%:

It is used for processing medical instruments at a temperature of 70 °C.

Treatment infected wounds, burns and other damage to the skin and mucous membranes.

Solution of chlorhexidine bigluconate 1%:

It is used for processing medical instruments, devices and working surfaces of equipment that are undesirable to be disinfected by heat treatment.

Disinfection of the skin of the patient and the hands of the surgeon before surgery. Prevention of infection of burns and postoperative wounds.

Solution of chlorhexidine bigluconate 5% and 20%:

It is used to prepare solutions of various concentrations on an aqueous, glycerin or alcohol basis.

Application method:

Chlorhexidine bigluconate is used for local treatment infectious diseases.

For the prevention of sexually transmitted diseases, it is recommended to use a 0.05% solution of chlorhexidine bigluconate no more than 2 hours after unprotected intercourse. Men are shown the introduction of 2-3 ml of the drug into the urinary canal, women 1-2 ml into the urinary canal and 5-10 ml into the vagina. In addition, it is recommended to treat the skin areas on the pubis, genitals and inner thighs with a solution. Urination is allowed 2 hours after the use of the drug, otherwise the effectiveness of chlorhexidine bigluconate is reduced.

Patients suffering from inflammation urinary tract(including urethritis and urethroprostatitis), the introduction of 2-3 ml of a 0.05% solution of chlorhexidine bigluconate into the urinary canal 1-2 times a day is indicated. The drug is recommended to be used every other day. The duration of the course of treatment is 10 days.

In dental and ENT practice, for the prevention of postoperative infection, a 0.05% or 0.1% solution of chlorhexidine bigluconate is usually prescribed 2-3 times a day in the form of rinses or irrigations.

For the treatment of wounds and burn surfaces, as well as other damage to the skin, a 0.05%, 0.02% or 0.5% solution of chlorhexidine bigluconate is usually used. The drug is used in the form of irrigation or applications 2-3 times a day. The application time is usually 1 to 3 minutes.

For disinfection of the surgical field, a 20% solution of chlorhexidine bigluconate pre-diluted 70% is used. ethyl alcohol(For 1 part of a 20% solution of chlorhexidine bigluconate, 40 parts of 70% ethyl alcohol are taken). The surgical field is disinfected twice with the resulting solution, the surgical field is treated a second time 2 minutes after the first disinfection.

AT urological practice lavage is indicated before diagnostic procedures (eg, cystoscopy) Bladder 0.02% solution of chlorhexidine bigluconate.

Preparation of solutions of a given concentration from a 20% solution of chlorhexidine bigluconate:

To prepare 1 l of a 0.5% alcoholic solution of chlorhexidine bigluconate, take 25 ml of a 20% solution of chlorhexidine bigluconate and add 70% ethyl alcohol to the mark.

To prepare 1 l of a 0.5% solution of chlorhexidine bigluconate, take 25 ml of a 20% solution of chlorhexidine bigluconate and add to the mark with distilled water or water for injection (sterile water).

To prepare 1 l of a 0.05% solution of chlorhexidine bigluconate, take 2.5 ml of a 20% solution of chlorhexidine bigluconate and add to the mark with distilled water or water for injection (sterile water).

To prepare 1 l of a 0.02% solution of chlorhexidine bigluconate, take 1 ml of a 20% solution of chlorhexidine bigluconate and add to the mark with distilled water or water for injection (sterile water).

To prepare 1 l of a 0.1% solution of chlorhexidine bigluconate, take 5 ml of a 20% solution of chlorhexidine bigluconate and add to the mark with distilled water or water for injection (sterile water).

Solutions must be prepared under aseptic conditions. Sterilization of ready-made aqueous solutions of the drug in an autoclave at a temperature of 116 ° C for 30 minutes is allowed.

Solutions prepared on the basis of hard water have a less pronounced bactericidal effect, which is explained by the formation of sparingly soluble salts of chlorhexidine. It is forbidden to sterilize the drug using ionizing radiation.

Undesirable phenomena:

When using the drug in some patients, the development of such side effects like dry skin pruritus, rash, photosensitivity, dermatitis.

With prolonged use of the drug in the form of rinses and irrigations oral cavity Patients experienced tooth discoloration, tartar formation, and altered taste sensations.

Contraindications:

Increased individual sensitivity to the components of the drug.

The drug is contraindicated for use in patients suffering from dermatitis.

The drug is used with caution in pediatrics.

The drug is not used in ophthalmology.

The drug is not used simultaneously with other antiseptic solutions.

During pregnancy:

With the local use of the drug in women during pregnancy and lactation, there was no effect of chlorhexidine on the health of the child. However, long-term use of the drug during pregnancy and lactation is not recommended.

Interaction with other drugs:

At a pH of more than 8, precipitation is noted. The use of hard water for the preparation of chlorhexidine solutions reduces its bactericidal properties.

The drug is not used in combination with anionic compounds, including soap.

The drug is not compatible with carbonates, chlorides, phosphates, borates, sulfates and citrates.

Chlorhexidine bigluconate increases the sensitivity of microorganisms to the action of kanamycin, neomycin, cephalosporin and chloramphenicol.

Ethyl alcohol enhances the bactericidal effect of chlorhexidine.

Overdose:

When using the drug according to the instructions, an overdose is not possible.

In case of accidental ingestion of the drug, gastric lavage is indicated using milk, mild soap, gelatin or raw eggs.

There is no specific antidote; in case of side effects, symptomatic therapy is carried out.

Release form of the drug:

A solution of 0.05% for external use, 100 ml in bottles of polymeric material with a nozzle, 1 bottle in a carton.

Solution 0.05% for external use, 100 ml in glass bottles, 1 bottle in a carton.

Solution 20% 100 ml in bottles of polymeric material, 1 bottle in a carton.

Solution 20% 500 ml in bottles made of polymeric material with a cap, 1 bottle in a carton.

A solution of 20%, 500 ml in bottles made of polymeric material with a cap, 16 bottles in a box.

Storage conditions:

The shelf life of the drug in the form of a 0.05% solution is 2 years.

The shelf life of the drug in the form of a 20% solution is 3 years.

The shelf life of the prepared solutions is 1 week.

Compound:

1 ml of the drug in the form of a 0.05% solution of chlorhexidine bigluconate contains:

Chlorhexidine bigluconate - 0.5 mg,

Excipients.

1 ml of the drug in the form of a 20% solution of chlorhexidine bigluconate contains:

Chlorhexidine bigluconate - 0.2 g,

Excipients.

Similar drugs:

Hepilor (Happylor) Pantestin (Panthestin) Medasept (Medasept) AHD 2000 (AHD 2000) Etonium (Etonium)

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Latin name: Chlorhexidini bigluconas
ATX code: D08AC02
Active substance: Chlorhexidine bigluconate
Manufacturer: Ali-San, Russia
Pharmacy leave condition: Without recipe

Chlorhexidine bigluconate has been successfully used as an antiseptic and disinfectant. The drug has stable properties. Remains active after application, and long time provides a bactericidal effect. This is one of the most common and safe means. The solution is able to stop the activity of many gramplus and gramminus pathogens. Approved for use during pregnancy, wounds can be treated for children, used in gynecology, dentistry for rinsing the mouth and throat, and venereal practice.

Indications

Chlorhexidine bigluconate is intended for therapeutic measures in the fight against pathologies caused by pathogens susceptible to its action:

Solution 0.1% (0.05 and 0.2)

• It is prescribed for prophylactic purposes after surgical interventions and for injuries in dentistry, laryngo-otorhinological organs.
• When disinfecting damaged mucous membranes of the mouth and genitals.
• Treatment of integuments to prevent infection after manipulations in surgical, obstetric and gynecological practice.
• As an antiseptic for wounds, scratches, abrasions, cuts and burns.
• For protection against viruses penetrating through the urethrogenital system.
• For gargling.

Chlorhexidine digluconate solution 0.5%

• For surface treatment, devices and tools medical purpose in a state heated to 75 0 С.

Chlorhexidine digluconate solution 1%

• Preventive measures for burn injuries of the epidermis.
• For disinfection and cleaning of the hands of doctors and staff before surgery.

There is also a solution with a concentration of 5 and 20% for the preparation of the composition using alcohol, glycerin or water.

Compound

Chlorhexidine bigluconate 0.05% 1 ml contains 0.5 mg similar substance. A mixture of 0.25 ml 20% corresponds to 0.2 g of the main component. Auxiliary elements - purified water up to 100 ml.

Medicinal properties

The drug is a derivative of dichlorobiguanide. The principle of operation is to penetrate into the phosphate compounds of cell membranes. As a result of the transfer of the solvent through the membrane, osmotic pressure occurs. Due to the high permeability, the strains lose the integrity of the nucleus and undergo lysis. Bacteria are deprived of potassium and phosphorus, lipoproteins are disaggregated, cytoplasms are destroyed. Due to the action of chlorhexidine, the pathogen dies, unable to continue life cycle. The agent is active against the following pathogens:

• Pseudomonas (partly)
• Proteus (moderately)
• Treponema pallidum
• Chlamydia trachomatis
• Ureaplasma
• Neisseri
• Bacteroides
• Gardnerella vaginalis
• Trichomonas
• Gonorrhoeae
• candida albicans
• herpesviridae.

Some types of fungi and viruses show resistance to the composition. The drug, when applied externally, is not able to be absorbed into the blood, undergo absorption, therefore it does not affect the body systemically. Antimicrobial functions are preserved in the presence of exudate, secretions and blood, but the effectiveness is slightly reduced.

It cleanses the skin well without causing damage and burns.

Release forms

The drug goes on sale in the form of a solution in glass (5 and 20%) or polymer bottles (0.05; 0.1; 0.2; 0.5%), with a capacity of 100 ml. The clear liquid has a pronounced bitter-salty taste. Top part plastic bottle is made in the form of a removable cap with a dispenser. The lid is screwed on top. Sometimes when rinsing your mouth, the tip flies off so as not to get hurt, it is better to hold it with your finger. The bottle is light, with a barely noticeable pink or blue tint, it is round or square, slightly flattened. The pack is cardboard, white, contains 1 jar and instructions.

Glass brown bottles are designed for clinics and come with an aluminum crimp cap and a rubber stopper. The lid is equipped with a dotted line for easy uncorking. Corrugated packaging contains 20 units and instructions.

Solution 0.5% 100 ml - 10 rubles.

0.1% 100 ml - 15 rubles.

0.2% 100 ml - 20 rubles.

0.5% 100 ml - 25 rubles.

5% 100 ml No. 20 - 300 rubles.

20% 100 ml No. 20 - 500 rubles.

Application methods

For prophylactic purposes, an aqueous solution of Chlorhexidine bigluconate 0.05% is injected into the cavity of the urethral or genital canal in an amount of 2-3 ml for men and 1-2 ml for women. Application is carried out within 2 hours after coitus. It is also necessary to lubricate the skin with liquid. Visiting the toilet for 120 minutes is not recommended, otherwise the efficiency of use will be significantly reduced.

For the treatment of throat and dental pathologies, rinses are prescribed with 0.05% or 0.1% composition. The liquid must be taken into the mouth, held for about half a minute, then spit out. Despite the rather bitter taste, it is better not to drink it. Children can dilute a small amount rosehip syrup.

With severe sore throat, the throat is lubricated with a special glass rod with turunda.

For the treatment of wounds, abrasions, scratches, burns, cuts cotton swab wetted in the composition, applied to the surface. It is also allowed to use applications of 0.1 or 0.5% for 3 minutes.

To disinfect the area prepared for surgery, a 20% preparation is required, diluted with 70% ethyl alcohol in a ratio of 1 to 40. The areas are treated twice with an interval of 2 minutes.

Before diagnostic procedures in urology, washing with a 0.02% solution is indicated.

In the treatment of infections associated with pathologies of the urogenital system, 2-3 ml of 0.05% is injected into the canal cavity twice a day every other day. Total time treatment takes 10 to 14 days.

Well disinfects chlorhexidine during epilation. To prevent the infection from getting into the irritated area, it is necessary to apply the drug 5 minutes before the procedure and 10 minutes after it.

Solution preparation

To obtain 1 l of a 0.5% solution for the treatment of surfaces and devices in medical offices for disinfection of hands of the doctor, as well as for medical procedures use the following schemes:

• 20 ml 20% - ethyl alcohol 70% up to the bottle label.
• 20 ml 20% - water for injection.

For the preparation of the drug requires sterile conditions. Processing in the autoclave at a temperature of 1100C within half an hour is allowed. When using hard water, chlorhexidine releases salts, which significantly reduces its properties. It is strictly forbidden to use devices with ion radiation.

Use in pregnancy

Contraindications

If susceptibility to the main substance is detected, the use is prohibited due to allergic reactions. Also, the drug is not prescribed in the following cases:

• Dermatitis
• Age up to 10 years
• During surgical intervention on the auditory organs
• In ophthalmology.

Drug Interactions

When diluted with hard water, bactericidal functions decrease, salt precipitation is possible.

The agent is not compatible with elements of the anionic group, chloride, phosphate, sulfate formations.

The drug reduces the resistance of strains to antibiotics several times.

Interaction with ethyl alcohol increases efficiency.

The use of other antiseptics does not work.

Adverse reactions

In some cases, itching and burning occurs during treatment. Discomfort passes quickly, so therapy can be continued. If dryness of the mucous membranes appears, when rinsing the throat and mouth, the tone of the teeth changes and a stone forms, it is better to additionally consult a doctor.

Overdose

When used externally, the excess is not dangerous. If liquid accidentally gets into digestive system, you can use milk and raw eggs to reduce intoxication.

Terms and conditions of storage

Composition 0.05% usable for 3 years, 20% - 12 months. After opening, the liquid can be kept for no more than a week. Store in a dark place, away from children.

Analogues

Plevasevt

Pliva Hrvatska, Croatia

Price: bottle 5% 1l - 130-150 rubles.

An antiseptic agent designed to dissolve membrane compounds of gram-positive and negative strains. Depending on the concentration of the prepared solution, it provides a bactericidal or bacteriostatic effect. Maintains stability for a long time after application. Does not render Negative influence on the epidermis, does not cause allergies.

The composition can be made with sterile water or alcohol. The temperature must be kept within 220C.

It is prescribed for diseases of the throat, for rinsing the mouth, for therapeutic purposes in venereological practice and gynecology. It is a prophylactic in the process of protecting against genital infections. It helps well with diaper rash, with disinfection of skin lesions. Used before surgical and diagnostic procedures. It is forbidden to use in concentrated form (except for the treatment of instruments, hands and surfaces in the medical field).

Produced in polypropylene bottles. Depending on the additional components, it differs in a blue or pink tint. Possesses bitter taste, has no smell. The pack is cardboard, white, with drawings of flowers, contains 1 bottle and instructions.

Advantages:

• Can be used diluted as a mouth and throat rinse
• Retains properties in the presence of exudate.

Flaws:

• Inconvenient packaging
• When combined with hard water, it loses its effectiveness.

Octenisept

Schulke & Mayer, Germany

Price: solution 50 ml - 550-600 rubles.

250 ml - 900-950 rubles.

Spray 50 ml - 450-500 rubles.

The drug does not contain chlorhexidine, but active ingredient octenidine hydrochloride has similar properties. Due to the hydrophobic effect on the cytoplasm, it destroys the membranes of pathogenic pathogens. The spectrum of activity covers most anaerobic and aerobic strains. With prolonged use, resistance does not develop. The product is non-toxic, when used externally, it is not capable of damaging tissues.

It is prescribed for the treatment of oral infections, urethral and genital pathologies caused by susceptible bacteria. It helps with sore throat, suitable for gargling. Disinfects infected wounds, cuts and burns. The method of application depends on the severity of the pathology.

Available as a clear solution in plastic bottles, has a slight specific smell and taste. A cardboard white pack with bright pink stains includes 1 bottle, instructions, applicators and sprayer.

The second option is a spray with a dispenser and a transparent propylene cap. It is convenient to use when treating the mouth and irrigating the throat. Can also be used for hand disinfection minor damage skin cover.

Advantages:

• Suitable for treatment during pregnancy
• Assigned to gargle, brings relief from sore throat.

Flaws:

• High price
• Incompatible with antiseptics based on iodine.

Farm group:

Release form: Liquid dosage forms. Solution for external use.

General characteristics. Compound:

Pharmacological properties:

Indications for use:

Important! Get to know the treatment

Dosage and administration:

Side effects:

Interaction with other drugs:

Contraindications:

Storage conditions:

In a dry place protected from light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Shelf life - 2 years. Do not use after the expiry date stated on the package.

Leave conditions:

Without recipe

Package:

0.05%; 0.2%; 0.5%; one%; 5% solution for external use, 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, 1000 ml in light-protective glass bottles with a screw neck, sealed with polyethylene stoppers, screw caps or caps with gaskets. 25 ml, 50 ml, 70 ml, 100 ml, 200 ml, 500 ml, 1000 ml in high-pressure polyethylene bottles with a polymer nozzle or with a special nozzle with a screw cap, or equipped with a spray pump and a protective cap made of polyethylene.3 l, 5 l in glass bottles with ground stoppers or screw-on plastic caps or in polyethylene canisters.

INDICATIONS FOR USE
Treatment of infected root canals of teeth in the treatment of pulpitis and periodontitis

WHY CHOOSE A LIQUID
Optimal antiseptic concentration for effective root canal sterilization
The original Luer Pro dosing system for the use of the drug to the last drop
Now you do not need to order at the pharmacy

The antiseptic liquid contains chlorhexidine bigluconate (2%), an antiseptic that actively suppresses the anaerobic flora, is active against gram-positive and gram-negative bacteria and remains active in the presence of blood and pus. The antiseptic liquid effectively sterilizes the root canal system.
When processing the prepared tooth cavity, chlorhexidine bigluconate does not reduce adhesion filling material to the tissues of the tooth.
Even when diluted 100 times (at a concentration of 0.02%), chlorhexidine bigluconate has a powerful microbicidal effect in the treatment of inflamed oral mucosa, and also reduces the formation of plaque during rinsing.
Chlorhexidine bigluconate is active in a neutral environment. Ethanol enhances activity. Chlorhexidine bigluconate is incompatible with alkalis, including calcium hydroxide. At a pH value of 8 or more, the activity of chlorhexidine decreases. Alkaline environment and sodium hypochlorite reduce the activity of chlorhexidine bigluconate and destroy it with the formation of a yellow-brown precipitate that stains the hard tissues of the tooth. Also, diluting a solution of chlorhexidine bigluconate with hard water reduces the activity of the drug. Compatible with antiseptics: benzalkonium chloride, cetrimide.
The antiseptic liquid is made for use in an aggressive biological environment in the temperature range from 32°C to 42°C (in the conditions of the oral cavity at a temperature of (37±1)0C and a humidity of 60-90%).

Antiseptic liquid is used for:
- treatment of infected root canals of teeth in the treatment of pulpitis and periodontitis;
- treatment of the prepared tooth cavity before filling;
- prophylactic rinsing of the mucous surface with gingivitis and initial forms of periodontitis;
- antiseptic washings periodontal pockets.

MODE OF APPLICATION
Using an endodontic needle with a side hole (or an irrigation syringe), the liquid is injected into the deep sections of the expanded root canal, kept for 1-3 minutes. Then the channel is washed with distilled water, dried with a sterile paper point or with a liquid for drying and degreasing the channels.
During multi-stage antiseptic treatment of the root canals of teeth with alternating sodium hypochlorite and chlorhexidine bigluconate, the rules for introducing antiseptic liquids should be strictly observed. After exposure of each liquid, the root canal should be thoroughly rinsed with distilled water several times and dried with a paper point.
For antiseptic treatment the prepared cavity of the tooth before filling, a solution of chlorhexidine bigluconate on a cotton turunda is introduced into the cavity and processed for 1 minute.
A solution for washing periodontal pockets and inflamed mucosal areas is prepared by diluting antiseptic liquid distilled water in a ratio of 1:10 (concentration of chlorhexidine bigluconate 0.2%). The resulting solution is irrigated with a pipette (or syringe) on the mucous surface.
Antiseptic washing of periodontal pockets is carried out in courses.
Antiseptic liquid may be recommended to patients as a rinse solution between periods of periodontitis treatment. For these purposes, the liquid should be diluted: 5-7 drops in a glass of water.
After each use, the material should be tightly closed with a lid.

↓ Show description ↓

BOR wrote: Liquid Chlorhexidine bigluconate 2% is a dichloride derivative of biguanide, an antiseptic for topical use. It has a bactericidal effect on gram-positive and gram-negative bacteria, it also acts on Candida albicans fungi, dermatophytes and lipophilic viruses. Causes the death of bacterial spores only when high temperature. Has no damaging effect on tissues. Prevents the formation of plaque, leading to the development of chronic gingivitis. Possessing bicationic properties, chlorhexidine binds strongly to the surface layers of the skin, mucous membranes and to the surface of the teeth, which ensures the preservation of the antiseptic effect for 12 hours. Chlorhexidine is not characterized by the development of microorganism resistance.
Application:
1. To process the surgical field (2 times with an interval of 2 minutes), use a 0.5% alcohol solution, which is prepared by diluting a 2% aqueous solution of chlorhexidine bigluconate with 70% ethyl alcohol in a ratio of 1:4.
2. For processing carious cavities, fissures and root canals - dial into a syringe with a needle for root irrigation required amount liquid Chlorhexidine bigluconate 2% and rinse the cavity, fissure or canal under slight pressure, avoiding the liquid getting on the oral mucosa. The liquid can also be applied with a cotton swab.
3. For rinsing (irrigation) of the oral cavity in the treatment of periodontal diseases, a 0.1 - 0.2% solution is used.
Attention!
- Liquid Chlorhexidine bigluconate 2% causes a transient discoloration of the hard tissues of the tooth with prolonged use;
- Avoid sharing liquids Chlorhexidine bigluconate 2% and sodium hypochlorite for root canal treatment;
— Liquid Chlorhexidine bigluconate 2% is not compatible with soaps, anionic detergents. Compatible with preparations containing a cationic group (benzalkonium chloride, cetrimonium bromide);
- Avoid contact with liquid Chlorhexidine bigluconate 2% on the oral mucosa;
- Allergic reactions and photosensitivity of the skin are possible. Use with caution.

So, those same bicationic properties interfere, oh how they interfere with the work of our adhesive systems!

www.ukrdental.com

Release form

Tooth gel 1%
Cream 1%
Solution for nar. approx. 0.05%, 0.2%, 0.5%, 1%, 4%, 5%, 20%

Mechanism of action

Chlorhexidine violates the integrity of the cell, causes precipitation of the cytoplasmic contents of bacteria, depending on the concentration, it has a bactericidal (at a concentration of more than 0.01%) or bacteriostatic (at a concentration of less than 0.01%) effect.

It has wide range antimicrobial action: active against most gram-positive and gram-negative microorganisms, facultative aerobes and anaerobes, prevents the growth of fungi, incl. Candida albicans, some protozoa and viruses. Changes bacterial absorption on the teeth, causes lysis of microbial cells, prevents the formation of microbial plaque, reduces inflammation of the gums and oral mucosa.

Main Effects

■ Antiseptic.
■ Deodorant.
Indications
■ Treatment and prevention of purulent inflammatory diseases mucous membrane of the oral cavity and periodontium: gingivitis, stomatitis, glossitis, periodontitis, candidiasis, lichen planus.
■ Treatment of carious cavities and root canals in the treatment of caries and its complications (pulpitis, periodontitis).
■ Treatment of damage from dentures and orthodontic appliances, wounds, decubitus ulcers, burn surfaces, surgeon's hands, surgical field.
■ Pre- and post-operative treatment of the oral cavity.
■ Disinfection of removable dentures.

Dosage and administration

Outwardly: for the treatment of carious cavities, root canals, the surgical field and the hands of the surgeon, 0.5% is used water-alcohol solution, mucous membranes - 0.06% solution and gel, oral baths - 0.05% aqueous solution 2-3 r / day.

Contraindications

■ Hypersensitivity.
■ Dermatitis.
■ Tendency to allergic reactions.

Precautions, therapy control

In the treatment of diseases of the mucous membranes of the oral cavity, it is recommended to use short courses, no more than 5-7 days (to avoid the development of dysbacteriosis).

Side effects

■ Dryness and itching of the skin, dermatitis.
■ Sticky hands for 3-5 minutes.
■ Black-brown staining of teeth, non-metallic fillings, tongue surface, acrylic prosthesis; deposition of tartar.
■ Violation of taste and sensitivity of the mucous membrane up to its loss (in the treatment of gingivitis and stomatitis).
■ Dysbacteriosis of the oral cavity (with prolonged use).
■ Allergic reactions.

Interaction

Synonyms

Chlorhexidine (Russia), Chlorhexidine bigluconate (Russia), Hibiscrab (UK), Corsodil (UK), Plivasept (Croatia), Elugel (France)

G.M. Barer, E.V. Zoryan

medbe.ru

Indications for use in dentistry

it antiseptic often included in the composition of rinses for the oral cavity. Their main purpose is to prevent and eliminate diseases such as gingivitis.

By its nature, this disease is inflammatory in nature. It occurs due to the accumulation and rapid reproduction of a large number of pathogens on the teeth and gums.

Without timely and proper treatment, the disease can worsen and lead to more serious complications.

How to use an antiseptic in this case? Rinsing your mouth with a solution of chlorhexidine bigluconate can help you cope with gingivitis for another early stages.

The solution is used for rinsing with stomatitis and some other inflammatory diseases oral cavity (periodontitis, glossitis).

How to apply the solution for prevention?

Chlorhexidine is excellent remedy to prevent the formation of plaque and tartar.

Due to its antibacterial properties, it protects well against these unpleasant phenomena. It is used for the treatment of removable dentures.

Instructions for use of the drug

For achievement maximum effect rinse your mouth with an antiseptic solution immediately after your teeth have been brushed.

By analogy with brushing your teeth, rinsing your mouth should be done 2 times a day. To do this, 10 ml of a 0.05% aqueous solution should be taken into the mouth and rinsed for about 30 seconds.

After that, it is not recommended to eat or drink liquid for 15-20 minutes. This will wash the chlorhexidine digluconate off the teeth and gums.

Mechanism of action

The tool has an effective ability to modify the properties of the cell membrane of bacteria and microorganisms.

When it is used in most bacteria, the cytoplasmic membrane is destroyed. They lose osmotic balance, which leads to inevitable death.

When treated with a solution of the oral cavity, it has only a local effect, not being absorbed into the tissues and not entering the blood. After rinsing, part of the product remains on the mucous membranes of the mouth for up to 24 hours. During this period, they have an antiseptic effect.

Advantages and disadvantages of the drug

The widespread use of the drug, including in dentistry, is due to the following points:

Among the shortcomings of the drug can be called:

• unpleasant taste with a hint of bitterness;
• low efficiency in the fight against viruses;
• the presence of side effects.

Contraindications and side effects

The product is contraindicated for people with high sensitivity to the main active ingredient - chlorhexidine bigluconate.

To rarer but possible side effects relate:

Feedback on the use of Chlorhexidine mouthwash for aphthous stomatitis:

Release form and storage conditions

The drug should be stored in the packaging in which it is produced. Transfusion into another container is not desirable. The product must be protected from direct sunlight and overheating above 25 ° C.

Keep out of reach of children. Valid for 3 years from date of manufacture.

Ointment Sibicort with chlorhexidine

Chlorhexidine in an amount of 1% is part of Sibicort ointment. In addition to it, the drug contains hydrocortisone (1%) and excipients.

The ointment is intended for the relief and treatment of diseases and skin lesions such as eczema in acute or chronic form, dermatitis (skin inflammation), neurodermatitis, concomitant infections of bacterial origin.

Only external application of Sibicort is allowed to eliminate dermatological problems. In dentistry, the drug is not used. Treatment of the oral cavity is not allowed.

High efficiency funds have been proven for years and does not cause controversy. Widely used in dentistry and other areas of medicine. He deservedly occupies a leading position among other antiseptic drugs not only in Russia, but throughout the world.

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History reference

The discovery of this chemical happened in the UK in the 1950s. His dosage form- bigluconate chlorhexidine - a few years later had a good commercial success. First of all, it was used as an external antiseptic in a fairly high concentration. Throughout its history, he has penetrated into every branch of medicine, including dentistry. For about forty years, doctors have known the property of this drug to inhibit the development of caries by killing pathogenic bacteria.

After outdoor processing this agent retains long-term antibacterial activity. This property made it possible to process surgical instruments and sterile rooms with the tool. In burn practice, wounds are washed with a weak solution. Perhaps there is no area in which chlorhexidine would not be used. Even newborns treat the umbilical cord with a 7% solution. How to gargle with chlorhexidine can be found on any website.

The use of chlorhexidine

To date, it is impossible to name a sphere where this antiseptic is used. Dental clinics, gynecological departments, operating units - the effectiveness of chlorhexidine is known everywhere. And due to its low cost, the popularity of its widespread use is even higher.

Without antiseptics in medicine it would be impossible to achieve positive results treatment. After all, they help fight foci of infections and inflammations locally, without a systemic effect on the entire body. And this means minimizing side effects and negative reactions of the whole organism. Antiseptics have a huge advantage over antibiotics. If the latter can cause resistance (resistance), then antiseptics will always effectively suppress and kill bacterial colonies.

When applied topically, it is difficult to choose an antiseptic more effective than chlorhexidine biluconate.

Chlorhexidine in dentistry

There are a lot of diseases in dentistry and they can significantly spoil the life of each of us. “A tooth ached” or “opened cheek” - this is the end of knowledge in dentistry of an ordinary patient. But these are symptoms of various diseases. There are diseases not only of the teeth and gums, the mucous membrane is sick, circulatory system tooth. Put accurate diagnosis can only be done by a specialist. And only after prescribing adequate treatment.

Thanks to chlorhexidine, many dental diseases are successfully treated in the early stages. A little later, you will learn how to apply, how and how much to rinse, and what this tool helps to get rid of.

One way or another, any disease is caused infectious agent. Our oral mucosa is a whole micro-ecosystem with its own bacteria, fungi and microorganisms. Being in a certain balance with a normal state of immunity, we do not get sick, and our teeth do not bother us. But if the number of negative bacteria grows more than the positive ones, then we get problems. You can compete with pathogenic microbes. To do this, you need to brush your teeth regularly, and not haphazardly, but correctly. The brush must be correctly selected, the paste should be used only of high quality, paying attention to the components. There is medicinal pastes, the use of which for more than two weeks can only harm. And the cleaning procedure itself should not take 30 seconds. Otherwise, there will be zero sense from such cleaning. Do you remember that the brush should be changed every three months?

Various elixirs and rinses can be a good addition to daily oral hygiene. They contain disinfectants, fluorine compounds, herbal extracts, which help to improve the cleaning result and keep the teeth healthy. In addition, after rinsing it is possible to maintain optimal level acid-base balance.

Chlorhexidine solution is also used as a rinse in medical practice. With one condition - this procedure must be prescribed by a doctor and have clear indications. This is by no means prophylactic, namely medical. And when treating, you must strictly follow the instructions.

The dentist should explain how often and how long rinsing should take to achieve the maximum therapeutic effect.

This solution has been used in therapeutic and surgical dentistry for many years and shows good results. The main thing is that the tool is affordable and effective. It is important to remember that if the doctor prescribed a certain concentration and a certain rinsing time, you should not increase this time yourself. More bacteria will not die, and the mucosa will be harmed, up to a chemical burn.

It is worth mentioning that chlorhexidine can be in the form of an alcohol or aqueous solution. It is the aqueous solution that is most popular in dental practice during operations and treatment of infections. There is a good evidence base confirming the high effectiveness of this drug in the treatment of diseases of the oral cavity.

Unfortunately, this drug is not omnipotent. Yes, indeed, its effectiveness against bacteria and fungi is very high, but viruses like herpes are beyond its power. There are also a number of microorganisms resistant to an acidic environment; for them, chlorhexidine is also not a threat.

But when it comes to aphthous stomatitis or bacterial, then in these cases, any dentist will confirm the effectiveness of the drug. It not only fights infection during rinsing, but also remains on the mucous membrane in the form of a microfilm for up to 24 hours, preventing the active reproduction of bacteria. This film persists despite saliva or the presence of food.

The nuances of the use of chlorhexidine

Chlorhexidine can exhibit slightly different efficacy and properties depending on two critical factors:

• concentration;
• exposure.

Pick up effective combination only your dentist can, neither you personally, nor a pharmacist in a pharmacy. Without correct diagnosis the use of the drug according to an indefinite scheme will only harm. As practice shows, when bacterial infection one concentration is needed, and with fungal diseases - another, even for different fungi and then a different concentration.

Exposure is no less important (this is the time of contact of the drug with the infection, in our case it is rinsing). If the infection is viral or bacterial cause, then rinsing for more than a minute is not recommended. But to effectively fight the fungus, you need to increase this time to five minutes. Obviously, it is about different concentrations solution.

Removal of a tooth

I sincerely want to believe that the days when dentists followed the path of least resistance, pulling teeth left and right, have passed. Dentistry over the past couple of decades, including domestic, has taken a huge step in development. New technologies, new tools, new preparations were in the hands of doctors, which make it possible to fight for the safety of the tooth. The problem is to change the mindset. In private clinics, this issue is resolved. High prices for services dictate high responsibility, which cannot be said about state institutions. One way or another, the teeth are removed and this is a real operation, albeit a simple one.

A prerequisite for surgical intervention should be cleanliness and high level hygiene. But no matter how we brush our teeth, we can’t get rid of bacteria so easily. This is where the same chlorhexidine comes in handy, which can be used to disinfect the cavity immediately before removal.

But what is the right thing to do after a tooth extraction? Remember: any rinsing after removal is contraindicated.

Many will be surprised by this, but it is true. The fact is that in place of the pulled out tooth, in fact, an open wound remains. The body itself has solved this problem. In the wound, the blood gradually coagulates, a clot forms, which prevents the entry of bacteria and microorganisms. But at first, this protection is not the most reliable, so you should carefully monitor the cleanliness of the oral cavity.

The dentist and surgeon must necessarily advise the patient on his further actions, warn what needs to be done and what should not be done. And how best to behave for the speedy restoration of the jaw. In most cases, you may be prescribed chlorhexidine baths after one or more teeth have been removed or other surgery. At the same time, the concentration active substance should not exceed 0.05%. This procedure should last from 20 to 30 seconds. Three times a day will be enough not to worry about the penetration of harmful microflora into the wound.

Focus your attention on the fact that you can only do baths so as not to damage the formed blood clot, otherwise bleeding may open and the healing process will have to be started all over again. After three days, you can safely proceed to rinsing with a solution of the same concentration, increasing the exposure time to one minute.

This is all that concerns the patient, but the doctor also has his own instructions. Before the start of the operation, even before the introduction of anesthesia, the oral cavity must be treated with an antiseptic. In such cases, chlorhexidine is used in the form of aerosols and aqueous solutions. Carrying out this procedure in the future will help to avoid additional problems associated with inflammatory processes.

But in a number of cases, different reasons complications are inevitable. The most common occurrence in such cases is alveolitis, in the common people “an empty hole”. This is just the option when the clot fell out or washed out and a deep non-healing wound remained. Here already rinsing and baths are indispensable. You will have to go back to the clinic for a consultation. Most likely, the doctor will suggest additional drug treatment and possibly given antibiotic therapy.

The fight against stomatitis

Stomatitis is a very generalized concept. For us, any wound in the mouth, inflammation - this is stomatitis. So it is in fact. There are a lot of reasons for its occurrence. This is infectious past illnesses, colds, weakened immunity - in a word, anything. Children are more susceptible to this infection, as they do not yet have a fully formed immune protection from viruses and bacteria. But, after looking at the wound in the mouth, only a dentist can confirm the diagnosis. Depending on the location of the inflammation, what we call stomatitis, dentists may call cheilitis, glassitis or palatinitis.

It is very difficult to understand the causes of occurrence and get to the root of evil in such diseases. The provoking factor can be:

• stomach diseases;
• problems with the heart and blood vessels;
• allergic manifestations;
• weakening of the immune system;
• disturbance in the process of metabolism.

What can we say about local damage to the gums when eating hard food or when we banally bit our cheek and an infection got into the wound. That is why in dental practice stomatitis is treated symptomatically. And how do you think they do it? That's right, the same chlorhexidine helps out. True, initially it is worth visiting the doctor and carefully listening to all his prescriptions. If you carefully read the article, you will understand that with this rinse you do not treat stomatitis, but only prevent the spread of germs in the oral cavity.

If you decide to ignore the trip to the dentist and prescribe yourself treatment with this drug, do not be surprised at the lack of results and do not scold pharmacies for slipping you a fake.

Moreover, choosing the wrong concentration, you can also earn a burn. Chlorhexidine itself can effectively fight a fungal infection caused by Candida spores. It is common in children preschool age. Properly selected treatment in the form of rinsing schemes will help to easily overcome it. When rinsing, remember that you should not use this antiseptic for more than 10 days.

Effective treatment of gingivitis and periodontitis

You may be wondering why we combined these two diseases? Everything is simple. They are interconnected and the second often arises as a consequence of the first. In simple terms, gingivitis is an inflammatory process that has touched the gums. It is usually superficial and easily treatable, but only if diagnosed early.

Periodontitis is a more severe form that penetrates deep into, affects the gum adjacent to the tooth, and can lead to loss of teeth altogether.

Without going into details, the main cause of these diseases can be safely called plaque on the teeth and tartar. Plaque is a mass accumulation of colonies of bacteria that must be seriously dealt with. Unfortunately, even chlorhexidine is powerless here. An integrated approach is important here and it is necessary to act in sequence.

1. The first step is to get rid of plaque and tartar. There are special procedures for this - professional cleanings teeth. There are several different methods but the main thing is the result.
2. The next step will be the disinfection of the formed gingival canals. When the breeding ground for bacteria is removed, chlorhexidine is put into the pocket.
3. And only now, after all the procedures carried out, it can be confidently stated that rinsing will bring the desired result.

There are cases when a solution of chlorhexidine is used not as a remedy, but as a prophylactic. it postoperative periods, conditions after traumatization of the jaw. At this time, using an ordinary toothbrush is simply unrealistic, and rinsing will not work, but irrigation will come in handy.

Inflammation of the gums is also often affected by owners of removable dentures. This happens due to improper storage. If you leave the prosthesis in a chlorhexidine solution at night, then in the morning, putting it on, you will not bring a colony of bacteria into your mouth, and therefore protect your gums from inflammation and abrasions.

Children and pregnant women

These categories of patients always cause increased interest and caution when taking any medications. During pregnancy, the drug can be used, but with some caution. Pharmacology tells us that chlorhexidine works only locally and does not penetrate the blood through the mucous membrane, there are no restrictions. But what if the integrity of the mucosa is broken by sores and wounds? The answer is obvious - refrain from using it. Consult your doctor and choose an alternative treatment.

As such, there are no contraindications for the use of the drug in a child. But parents should be very careful. Chlorhexidine is very unpleasant in taste and can enter the esophagus during rinsing. If you swallow a couple of drops, then nothing terrible will happen, but if it does a large number of, then this does not bode well. A drug that kills bacteria in such low concentrations will also have a detrimental effect on the entire body, once it enters the digestive system.

Here, nursing mothers should still refrain from using this remedy. Although rare, it can provoke allergic reactions. And during lactation, the presence of allergens in the blood is completely useless - neither mother nor baby.

Side effects of use

Medicines are never perfect. They are able to cure one disease and lead to a new problem, and chlorhexidine is no exception. At long-term treatment in the form of baths or mouthwashes tooth enamel may turn yellow. Especially places where bacteria accumulate (plaque and stone) will stand out, they will acquire a brown color. The tongue may also darken. And if the language after giving up treatment will come normal, then the teeth will have to be whitened by professional means.

This effect can be somewhat reduced by refusing coloring food for the duration of treatment, but not completely eliminated.

There is another problem. High efficiency in the fight against microbes means the destruction of positive microflora. Prolonged rinsing of the mouth will leave the mucosa without "defenders" and open the way to infection. The very first symptom will be the appearance of bad breath. This condition is called halitosis by dentists.

Chlorhexidine does not get along well with other medicines and toothpastes, so they should be selected with caution. And from drugs with iodine in general, completely refuse for the duration of treatment.

The question often pops up on the forums about how to dilute chlorhexidine. Friends, don't be selfish. Currently sold in pharmacies enough ready-made solutions with a safe concentration and their price is not at all high. Everywhere there is an insert-instruction for use, which should not be neglected and should be read once again before starting treatment.

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Chlorhexidine bigluconate - instructions for use (composition, form of release, pharmacological action)

The active component of the medicinal alcohol and aqueous solution is chlorhexidine bigluconate. Purified water acts as an additional component. The drug is available as a 0.05% solution for topical use.

In the pharmacy network, this product is sold in a volume of 100 ml. There is also a 20% Chlorhexidine solution available in 100 and 500 ml vials. In addition, there are gels, ointments, sprays and suppositories, which include this active ingredient.

The drug Chlorhexidine has a powerful disinfecting and bactericidal effect. Most pyogenic and pathogenic microorganisms that cause infectious and inflammatory diseases in the body.

Taking into account the results of clinical studies, it was found that this remedy has a detrimental effect on pathogenic fungi, and can be used for thrush (candidiasis). 1% solution concentration is able to inhibit the growth and development of lipophilic viruses.

This remedy has a detrimental effect on pathogens skin diseases, such as ringworm. A detrimental effect has been noted in relation to candidiasis.

Indications for the use of chlorhexidine

This bactericidal pharmaceutical agent is widely used in medical practice for the purpose of disinfecting surgical instruments, treating the operated area, as well as for cold sterilization of other medical devices. Recently medical specialists consider justified the use of chlorhexidine for the treatment inflammatory process in the bladder (cystitis).

In this case, the agent is used to flush the bladder cavity through urinary catheter. More wide application this remedy was obtained in obstetric and gynecological practice. This branch of medicine uses it in such cases:

1. With a prophylactic purpose at the risk of developing an infectious inflammatory processes before performing abortions, before surgical procedures, intrauterine examinations, childbirth, diathermocoagulation of cervical erosion, and also before setting up an intrauterine contraceptive;
2. To prevent infection infectious diseases sexually transmitted (genital herpes, ureaplasmosis, chlamydia, gonorrhea, trichomoniasis);
3. In an integrated drug therapy colpitis and bacterial vaginosis.

In dermatological practice, a 0.5% aqueous solution of Chlorhexidine is used for the face and disinfection of wound surfaces, damaged mucous membranes, burns, bedsores and abrasions. A highly effective remedy has been noted in the prevention of dental diseases such as periodontitis, stomatitis and alveolitis.

In otolaryngological practice, the solution is instilled into the ear and nose for the purpose of disinfection. How to gargle with chlorhexidine will be detailed below.

How to dilute chlorhexidine

Pharmacy chains offer 0.1%, 0.0 5%, 5% and 20% solutions active drug. The first two mentioned concentrations do not require additional dilution and can be used for therapeutic purposes.

In this case, the main thing is to keep the proportion. If it is necessary to obtain 0.5 l of a ready-made solution with an active substance concentration of 0.05%, then 12.5 ml of a solution with a concentration of 20% will be required for dilution.

The taken volume of the concentrated solution must be brought to 0.5 l with distilled water. To obtain 200 ml of a 0.0 1% solution of the drug from an initial concentration of 5%, it is necessary to mix 0.4 ml of a concentrated solution and 199.6 ml of distilled water.

In order to obtain a 0.05% solution from a given concentration, it is enough to mix 198 ml of distilled water and 2 ml of a concentrated solution.

Chlorhexidine mouthwash

For this procedure, you can use both the usual solution of Chlorhexidine and preparations containing this component. These drugs include Hexicon, Gibitan, Amident, Korsodil.

Most often, this tool is used to disinfect the oral cavity with stomatitis and after tooth extraction. For the treatment of stomatitis, you can use aqueous solution Chlorhexidine with a concentration of 0.02 percent.

The frequency of rinsing with this disease is 2-3 times a day, after preliminary cleaning of the teeth. The duration of the solution in the mouth when rinsing is at least 1 minute. After cleansing the mouth, it is not recommended to drink and eat.

When using rinse, it is important not to damage blood clot formed at the site of tooth extraction. In this case, it is necessary to avoid intensive rinsing, resorting to the so-called retention of the solution in the mouth.

Swelling of the oral mucosa, characteristic of gingivitis, is successfully treated by rinsing with 0.05% antiseptic. For the purpose of treatment, it is recommended to rinse the oral cavity with this remedy 2 times a day, after brushing your teeth. Such manipulations can not only cure some diseases of the oral cavity, but also contribute to the oppression pathogenic microflora contained in dental plaque.

Many people have heard of such a phenomenon as pericoronitis. it dental disease characterized by inflammation of the gum tissue, in the thickness of which a wisdom tooth erupts. In order to prevent the spread of an infectious inflammatory process during pericoronitis, it is recommended to rinse with Chlorhexidine 3 times a day.

Chlorhexidine, instructions for use in gynecology

The antiseptic solution, is used in gynecological practice, as a rule, for douching. This procedure is carried out both in a antenatal clinic and at home. The modern pharmaceutical industry offers special packaging with ready solution equipped with vaginal attachments.

In the absence of these products, you can use an ordinary rubber syringe. The Chlorhexidine douching procedure has the following plan:

• Before starting the action, it is recommended to sterilize the syringe or vaginal nozzle. For this purpose, it is necessary to pour boiling water over them;
• The finished antiseptic solution is strictly forbidden to be heated, since a change in its temperature leads to a change in medicinal properties;
• The sterilized nozzle or syringe must be lubricated with sterile vaseline oil;
• An antiseptic solution is gently injected into the lumen of the vagina. The disposable volume of antiseptic for douching is 10 ml.
• After a short retention of the solution in the lumen of the vagina, by means of the tension of the muscles of the perineum, it must be pushed into the bath.

The duration of the course of treatment is 5-6 days.

In dentistry

In this area, this antiseptic and bactericidal agent is used to eliminate such problems:

• carious lesions of the teeth;
• Infectious and inflammatory diseases of the oral mucosa;
• Disinfection of the mouth after tooth extraction;
• For the rehabilitation of the mouth from the fungus (with candidiasis) and the presence of a purulent focus;
• To remove tartar;
• With inflammation of the gums.

In this case, the drug is used for rinsing, with a frequency of 2-3 times a day.

Chlorhexidine for children

In pediatric practice and pediatric otolaryngology, this remedy is widely used. His healing effect noted in relation to purulent-inflammatory lesions of the oropharynx (tonsillitis, with tonsillitis, pharyngitis, laryngitis). It is advisable to use the drug for the treatment of children in such cases:

• For cleansing the sinuses with gaumoritis and sinusitis;
• For inhalation in diseases respiratory tract inflammatory nature;
• For rinsing the throat with infectious and inflammatory lesions of the mucous membrane of this area.

Chlorhexidine during pregnancy

Local use of this pharmaceutical agent acceptable in this situation, because active ingredients the drug does not have a toxic and teratogenic effect on the body of the expectant mother. With a therapeutic purpose, expectant mothers can safely use a solution for the throat (gargle), as well as for the purpose of disinfecting the external genital organs.

To get rid of acne, you can wipe your face with this remedy. In this case, you can wipe your face with chlorhexidine at a concentration of 0.05%.

Video - chlorhexidine for the face

Chlorhexidine's analogs

Many people are interested in the list of antiseptic and bactericidal medicines with similar activity to Chlorhexidine. The closest means are:

• Tsiteal. This tool is widely used for antiseptic treatment of mucous membranes and skin;
• Baktosin. This tool is often used to treat the skin in places of insect bites, with microcracks, wounds and other injuries;
• Mukosanin. This analogue is used for the rehabilitation of the skin and mucous membranes with infectious and inflammatory lesions;
• Instillagel. This powerful bactericidal agent is used in surgical practice to treat the surgical field.

Miramistin or Chlorhexidine, which is better

If we talk about comparing these two antiseptic drugs, then we can say that Miramistin has an advantage over Chlorhexidine due to a milder effect on the mucous membrane and the absence of a specific taste and smell.

When this drug enters the gastrointestinal tract, a person may not worry about the development of side effects. From point of view pricing policy, Chlorhexidine is a budget tool available to everyone. If it is planned to process medical instruments, then it is preferable to use a concentrated solution of Chlorhexidine.

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