Pharmatex instructions for use, contraindications, side effects, reviews. Indications for the use of Pharmatex. Influence on the ability to drive a vehicle

Pharmatex is a contraceptive drug for topical use, characterized by spermicidal and antiseptic action.

Release form and composition

Pharmatex is produced in the form of the following dosage forms:

• capsules: oval, soft, translucent, light yellow; inside the capsules contains an emulsion of white color to white with a yellowish tint; a slight delamination of the capsule filler is possible (6 pcs in an aluminum and PVC blister, in a cardboard bundle 1 or 2 blisters);
• vaginal tablets: round, white, there is a hole in the center (12 pcs in a polypropylene tube, hermetically sealed with a polyethylene stopper with silica gel, 1 tube in a cardboard box);
• vaginal cream 1.2%: homogeneous white mass with a lavender smell (72 g each in an aluminum tube with a membrane, equipped with a polyethylene screw cap and a perforator for piercing the membrane, 1 tube in a cardboard bundle);
• vaginal suppositories: cylindrical in shape with a cone-shaped end, white, with a specific smell (5 suppositories in a strip of PVC film with a polyethylene sheath, in a cardboard box 1 or 2 strips).

The composition of 1 capsule includes:

• auxiliary components: macrogol 400 - 75 mg, dimethicone 1000 - 1042.2 mg, macrogol-7-glyceryl cocoate - 150 mg, hyprolose - 105 mg, colloidal silicon dioxide - 90 mg.

The capsule shell Pharmatex contains: glycerol - 189.75 mg, gelatin - 385.25 mg.

The composition of 1 vaginal tablet includes:

• active substance: benzalkonium chloride - 20 mg;
• auxiliary components: macrogol 6000 - 20.7 mg, sodium bicarbonate - 111 mg, lactose monohydrate - 363 mg, lemon acid- 96 mg, magnesium stearate - 5.3 mg, microcrystalline cellulose - 172 mg, colloidal silicon dioxide - 12 mg.

100 mg vaginal cream 1.2% contains:

• active substance: water solution benzalkonium chloride 50% - 2.4 mg (in terms of benzalkonium chloride - 1.2 mg);
• auxiliary components: purified water - up to 100 mg, citric acid - 0.002 mg, lavender oil - 0.05 mg, Tefoz 63 (macrogol and ethylene glycol palmitostearate) - 24 mg, disodium hydrogen phosphate dodecahydrate - up to pH 3.5–5.5.

The composition of 1 vaginal suppository (weight 1600 mg) includes:

• active substance: an aqueous solution of benzalkonium chloride 50% - 37.8 mg (in terms of benzalkonium chloride - 18.9 mg);
• auxiliary components: solid fat WitepsolS 51 - 1553.1 mg, hyprolose - 9.1 mg.

Indications for use

Pharmatex is used as a local contraceptive for women. reproductive age in the following cases:

• contraindications for use intrauterine contraception or oral contraceptive drugs;
• skipping or being late in taking regularly used oral contraceptives;
• irregular sexual contacts;
• postpartum period and lactation period;
• abortion;
• menopause;
• as an additional local contraceptive for established intrauterine device or vaginal diaphragm.

Contraindications

• irritation and the appearance of ulcers on the mucous membrane of the vagina and cervix;
• vaginitis;
• hypersensitivity to any of the components of the drug.

Method of application and dosage

All forms of the drug Pharmatex are intended for vaginal application.

Capsules

The capsule is inserted as deep as possible into the vagina 10 minutes before sexual intercourse in the supine position. The action of the contraceptive lasts 4 hours. Before repeated coitus, it is necessary to enter new capsule.

Vaginal tablets

The tablet is slightly moistened with water and in the supine position is injected as deep as possible into the vagina (for complete dissolution) 10 minutes before sexual intercourse. The duration of the contraceptive is 3 hours. Before re-coitus, you must enter a new pill.

Vaginal cream 1.2%

It is necessary to replace the cap on the tube with a dispenser and gently squeeze out the contents of the tube until the dispenser is completely filled (the piston is on the stop) in such a way as to exclude the appearance of air bubbles. Then it is necessary to disconnect the dispenser from the tube and close it with a cap.

The cream is injected deep into the vagina by means of a dispenser in the supine position, slowly pressing on the piston. The duration of the contraceptive is 10 hours. Before repeated coitus, a new dose of cream is necessarily introduced. One dose (5 g of cream) is used for one sexual intercourse only.

Suppositories vaginal

The suppository is inserted as deep as possible into the vagina in the supine position 5 minutes before sexual intercourse. The duration of the contraceptive is 4 hours. Before re-coitus, the introduction of a new suppository is necessary.

Side effects

• pain when urinating;
• burning sensation and itching in the vagina and / or penis of a partner;
• contact dermatitis;
• allergic reactions.

In case of side effects, you should stop using Pharmatex.

If the severity of the side effects mentioned above increases or other side effects, you should seek medical advice.

special instructions

Pharmatex is a contraceptive, so its use during pregnancy is unacceptable.

When pregnancy occurs while using the drug negative impact its course was not detected. Benzalkonium chloride is not excreted with breast milk and can be administered during lactation.

The effectiveness of the contraceptive action of the drug depends on the correctness of its use. When toileting the genitals 2 hours before and 2 hours after sexual intercourse, it is forbidden to use soap in order to avoid the destruction of the active substance of Pharmatex. After coitus, the toilet of the external genital organs is carried out exclusively clean water. Vaginal irrigation is allowed only 2 hours after intercourse. After the introduction of the drug into the vagina, due to the likelihood of a decrease in the contraceptive effect of Pharmatex, you can not swim in open water, the sea and pools, as well as take a bath. In diseases of the vagina, the treatment of which requires the use of vaginal medicines, Pharmatex is temporarily canceled.

Information about negative impact drug on the ability to drive vehicles and other mechanisms are absent.

drug interaction

Any drug, including soap and the solutions in which it is included, reduces the spermicidal effect of Pharmatex. The use of iodine solutions (including iodonate and 0.1% solution) leads to drug inactivation.

Analogues

Analogues of Farmateks are: Spermateks, Benateks, Farmagineks, Konrateks, Eroteks.

Terms and conditions of storage

Store at a temperature not exceeding 25 ° C, keep out of reach of children. If the suppositories melt when exposed high temperatures, it is necessary to substitute them under the jet cold water or refrigerate to return to original shape. The composition of the drug will not change.

The shelf life of Pharmatex capsules is 2 years. Shelf life of vaginal tablets and suppositories, as well as vaginal cream 1.2% - 3 years.

Terms of dispensing from pharmacies

Released without a prescription.

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Published on this page detailed instructions by application Pharmatex. Available dosage forms listed contraceptive drug(capsules, tablets, vaginal tampons and suppositories 20 mg, cream 1.2%), as well as its analogues. Information is provided on the side effects that Pharmatex can cause, on interactions with other drugs. In addition to information about the diseases and conditions for the treatment and prevention of which a drug is prescribed (non-hormonal contraception), the algorithms for admission, possible dosages for women are described in detail, the possibility of using during pregnancy and lactation is clarified. Annotation to Pharmatex is supplemented by reviews of patients and doctors.

Instructions for use and scheme of use

Capsules

Lying on the back, the capsule is injected deep into the vagina no later than 10 minutes before sexual intercourse. The duration of action of the drug is 4 hours. Be sure to introduce a new capsule before each repeated sexual intercourse. 1 capsule is designed for one sexual intercourse.

Tablets

Lying on the back, the tablet is injected deep into the vagina no later than 10 minutes before sexual intercourse. The duration of action of the drug is 3 hours. Be sure to introduce a new tablet before each repeated sexual intercourse. 1 tablet is designed for one sexual intercourse.

Candles

Lying on the back, the suppository is injected deep into the vagina no later than 5 minutes before sexual intercourse. The duration of action of the drug is 4 hours. Be sure to introduce a new suppository before each repeated sexual intercourse.

Cream

Before the introduction of the vaginal cream, you should attach the dispenser to the tube instead of the cap. Gently squeeze out the contents of the tube until the dispenser is full (up to the stop of the piston) so that no air bubbles form. Disconnect the dispenser from the tube. Close the tube with a lid. Lying on your back, insert the cream deep into the vagina using a dispenser, slowly pressing the plunger. The duration of action is 10 hours. Be sure to introduce a new dose of cream before each repeated sexual intercourse. 1 dose (5 g of cream) is designed for one sexual intercourse.

Tampon

Before inserting a vaginal tampon, take it out of its protective packaging. Put middle finger one hand to the center of the flat surface of the swab. Parting the lips of the vulva with the other hand, insert the swab deep into the vagina, up to contact with the cervix. The protective effect occurs immediately and lasts 24 hours. During this period, there is no need to change the tampon, even if several sexual intercourses follow one after another. You can remove the tampon 2 hours after the last intercourse. In any case, the tampon should be removed 24 hours after insertion into the vagina. In the event that difficulties arise with the removal of the tampon, it is necessary to squat down (thereby reducing the depth of the vagina) and pull out the tampon, holding it between the index and middle fingers.

The frequency of use of the drug is limited by the individual tolerance of the active substance and the frequency of sexual intercourse.

It is possible to use Pharmatex together with vaginal diaphragm or the Navy.

Release forms

Vaginal capsules 18.9 mg.

Tablets vaginal 20 mg.

Candles vaginal 18.9 mg.

Cream vaginal 1.2%.

Tampons vaginal 1.2 g.

Compound

Benzalkonium chloride + excipients.

Pharmatex- vaginal contraceptive. The spermicidal effect is due to the ability of the drug to destroy the membranes of spermatozoa (first the flagella, then the heads), which leads to the impossibility of fertilizing the egg with a damaged spermatozoon. The effect develops immediately after the introduction into the vagina.

The drug is active against Neisseria gonorrhoeae, Chlamydia spp. (chlamydia), Trichomonas vaginalis, herpes simplex type 2 (herpes virus), Staphylococcus aureus(staphylococcus).

Weakly active against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.

He is active against Mycoplasma spp.

He affects normal microflora vagina (including on a Doderlein wand) and hormonal cycle.

Pharmacokinetics

Benzalkonium chloride is not absorbed by the vaginal mucosa. Removed by simple rinsing with water and with normal physiological secretions.

Indications

Local contraception for women of reproductive age, including:

• if there are contraindications to the use of oral contraceptives or intrauterine contraception;
• in postpartum period;
• during lactation;
• after termination of pregnancy;
• in the period preceding menopause;
• with irregular sexual intercourse;
• when skipping or being late in taking constantly used oral contraceptives;
• as an additional local contraception when using a vaginal diaphragm or IUD.

Contraindications

• vaginitis;
• ulceration and irritation of the mucous membrane of the vagina and cervix;
• hypersensitivity to the components of the drug.

special instructions

The effectiveness of contraception is associated exclusively with strict observance rules for its use:

• inject a capsule (tablet, suppository, cream) so that the selected dosage form penetrated as deeply as possible into the vagina, preferably in the supine position;
• wait for the complete dissolution of the capsule or tablet in the vagina for at least 10 minutes, suppositories - at least 5 minutes to active substance was completely released;
• be sure to introduce a new capsule (tablet, dose of cream, suppository) before each repeated sexual intercourse;
• it is forbidden to use soap for the toilet of the genital organs 2 hours before intercourse and within 2 hours after intercourse, because. soap, even in residual quantities, destroys the active substance of Pharmatex;
• immediately after sexual intercourse, the external toilet of the genital organs is possible only with clean water or with the help of a foaming agent Pharmatex, which does not contain soap, which includes benzalkonium chloride; vaginal irrigation is carried out 2 hours after intercourse;
• with Pharmatex introduced into the vagina, you can not take baths, swim in the sea, pool and reservoirs because of the danger of reducing the subsequent contraceptive effect;
• since Pharmatex contains benzalkonium chloride, it is necessary to interrupt its use if any vaginal diseases occur or their exacerbation occurs;
• in the event that it becomes necessary to treat diseases of the vagina and / or prescribe any other drug vaginally, it is necessary to wait until the end of treatment before resuming (starting) contraception with Pharmatex.

Influence on the ability to drive vehicles and control mechanisms

No data on negative influence drug on the ability to drive vehicles and other mechanisms.

Side effect

• contact dermatitis;
• itching and burning in the vagina and / or partner's penis;
• painful urination.

drug interaction

Simultaneous use with drugs used vaginally is not recommended. Any drug introduced into the vagina can inactivate the local spermicidal action of Pharmatex.

Iodine solutions (including 0.1% iodonate solution) inactivate the drug.

Soap and solutions containing it may reduce the spermicidal effect of the drug. Do not irrigate the vagina before and after sexual intercourse, because soap, even its traces, destroys the active substance.

Analogues medicinal product Pharmatex

Structural analogues for the active substance:

• Benatex;
• Benzalkonium chloride;
• Dettol Benzalkonium Chloride;
• Countertex;
• Spermatex;
• Farmaginex;
• Erotex.

Use during pregnancy and lactation

The drug is a contraceptive, it is not used during pregnancy. When pregnancy occurs against the background of benzalkonium chloride contraception, no effect on the course of pregnancy was found.

Pharmatex is not excreted in breast milk, the drug can be used during lactation.

Pharmatex is a local non-hormonal contraceptive that protects, among other things, from sexually transmitted infections. The tool is recommended for use by women who have contraindications to the use of hormonal and intrauterine contraceptives. Additionally, it can be used as an auxiliary measure of protection for other options for protection, namely the drug "Farmatex". Reviews about its use are quite contradictory.

How Pharmatex works

The benzalkonium chloride contained in it has excellent spermicidal and antiseptic properties. This substance, destroying the shell of spermatozoa, does not allow them to fertilize the egg. Accurate adherence to instructions reduces the risk unwanted pregnancy practically to zero.

Benzalkonium chloride is absorbed on the walls of the vagina without being absorbed into the mucous surface. Either naturally, or during the procedure of intimate hygiene.

The drug, on average, begins to work after 10 minutes after its direct introduction into the vagina. single dose funds are designed for only one ejaculation. During secondary intercourse, it will be required in without fail introduce a new dose of the drug "Pharmatex". Reviews of the use of this drug sometimes contain information about such a side effect as feeling quite strong feeling burning. Most likely, this is a manifestation of an allergic reaction to a biologically active substance.

Additional action of the drug "Pharmatex"

Benzalkonium chloride prevents the penetration of the following bacteria and viruses

• gonococcus;
• chlamydia;
• genital herpes virus;
• trichomonas;
• golden staphylococcus.

The highest probability of protection against STDs is guaranteed when used with a condom.

A drug " Pharmatex": analogues

This medical preparation can be successfully replaced by one of the analogue agents, which also have an active active substance - benzalkonium chloride.

These include drugs:

- Benatex;

- "Kontratex";

- "Pharmagineks";

- "Spermateks";

- Eroteks.

A drug Pharmatex: reviews specialists

Most gynecologists agree in their opinions: the drug should be used if there is no allergic reaction to the active substance in both partners and there are no objections to the use of this drug as an additional contraceptive and antiseptic at the same time as barrier contraceptives in particular with a condom.

Types of preparations "Pharmatex"

Vaginal tablets "Farmateks". Apply 10 minutes before the scheduled

sexual contact. Action time 3 hours

Contraceptive candles "Farmateks". Used 5 minutes before sexual intercourse. Action time 4 hours.

Vaginal cream "Farmateks". Begins to act immediately after administration. Action time 10 hours.

Vaginal tampon "Farmateks". It begins to act after the introduction. Time of action - days. It is removed 3 hours after the last sexual intercourse. Does not require replacement for repeated sexual contact.

A drug " Pharmatex": reviews women

In general, the reviews are good. During application this drug in women, there is a feeling of abundant moisture in the vagina, and this, in turn, somewhat reduces pleasure. Quite often there is an inconvenience, most often psychological, of the administration of the drug. The inability to fully visit the shower, as well as spontaneous unplanned sex outside the home, the use of this contraceptive is not possible. However, many women say that they have been using this contraceptive for several years and have no complaints.

The analogues of the drug Pharmatex are presented, in accordance with medical terminology, called "synonyms" - drugs that are interchangeable in terms of effects on the body, containing one or more identical active substances. When choosing synonyms, consider not only their cost, but also the country of origin and the reputation of the manufacturer.

Description of the drug

The effect develops 10 minutes after the introduction into the vagina.

In vitro, the drug is active against Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Herpes simplex type 2, Staphylococcus aureus.

Weakly active against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.

He is active against Mycoplasma spp.

He affects the normal microflora of the vagina (including the Doderlein stick) and the hormonal cycle.

List of analogues

Note! The list contains Pharmatex synonyms that have a similar composition, so you can choose a replacement yourself, taking into account the form and dose of the medicine prescribed by your doctor. Give preference to manufacturers from the USA, Japan, Western Europe, as well as well-known companies from Eastern Europe: Krka, Gedeon Richter, Actavis, Egis, Lek, Geksal, Teva, Zentiva.

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Pharmatex

Pharmacological properties

Pharmacokinetics

Indications for use

Contraindications

Pregnancy and lactation

Dosage and administration

Side effects

Overdose

Interaction with other drugs

special instructions

Influence on the ability to drive a vehicle

Release form

Storage conditions

Best before date

Holiday conditions

Manufacturer

The information on the page was verified by the therapist Vasilyeva E.I.

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Pharmatex is a local contraceptive with antiseptic and spermicidal action, which is available in several dosage forms and is produced by the French pharmaceutical company Lab. Innotech International.

About the drug, composition, form of release

The drug Pharmatex is available in the form of vaginal tablets, vaginal suppositories and vaginal cream:

• Pharmatex tablets have round shape and a small hole in the middle, they contain 20 mg of active ingredient. Produced in a blister for 12 cells, packed in a cardboard box.
• Contraceptive candles Farmateks have the shape of a cylinder with a cone at the end, white. They contain 18.9 mg of benzalkonium chloride. Suppositories are sealed in a contour package, 10 pieces in a box.
• The cream is available in aluminum tubes of 864 mg with a dispenser. One dose contains 28.8 mg active component. The cream has a pleasant homogeneous consistency, white in color and flavored with lavender fragrance.

The active substance of the drug is benzalkonium chloride. it chemical compound It has spermicidal, bactericidal, antiviral and antifungal properties. Spermicidal action is carried out due to the surface activity of the active substance Farmateks. It covers the entire vagina with a thin film, slowing down the movement of the male germ cell towards the cervix.

Influencing the bioelectrical balance of the phospholipid-protein layer, the drug damages the membrane of the sperm head and causes the flagella to separate from the body, which makes fertilization from the damaged germ cell impossible.

The drug works very low concentrations- 0.005%. During the first 20 seconds of interaction of the seminal fluid with the drug, the activity of spermatozoa is eliminated. One dose of the drug is enough to neutralize the middle portion of the ejaculate.

The effectiveness of the drug is very high, however, if all the rules for its use are not observed contraceptive action may be lost.

The Pearl Index at Pharmatex is 3-4%. Those. in a year out of 100 women, 3-4 became pregnant using this local contraceptive. The drug has no effect on fertility and libido.

The bactericidal activity of the drug is directed against many sexual infections - gonococcus. chlamydia, trichomonas, herpes virus type 2 and Staphylococcus aureus. Unfortunately, its action does not apply to equally common diseases - mycoplasma, candida, vaginal gardnerella, etc. The drug is not absorbed into the systemic circulation, but is only absorbed on the walls of the vagina.

What helps Pharmatex? - testimony

The main use of the drug is to ensure safe intercourse, both in relation to unplanned pregnancy and in relation to some sexually transmitted diseases.

What helps Pharmatex? Pharmatex tablets, suppositories or cream are used in the following situations:

• at breastfeeding and immediately after childbirth;
• if it is impossible to use oral methods of contraception;
• with rare sexual intercourse, when it is inappropriate to use oral contraceptives;
• in cases where the birth control pill is missed;
• in the period before menopause;
• how additional remedy contraception;
• after an abortion or miscarriage.

Pharmatex does not provide complete protection against unwanted pregnancy, especially for young couples (under 35 years old), in which the sexual partner has saturated semen. enough active sperm.

Instructions for use Pharmatex, dosage

administration of Pharmatex cream

According to the instructions, Pharmatex tablets must be injected deep into the vagina, lying on your back. Pre-tablet must be moistened (!). The introduction is carried out 10 minutes before the onset of sexual intercourse.

• The tablet dosage form is valid for no more than 3 hours.

Pharmatex suppositories are administered vaginally in the same position as tablets, but at least 5 minutes before the onset of coitus. Suppositories melt quickly enough at body temperature, so it is better to keep them in the refrigerator beforehand and insert them into the vagina immediately after removing them from the contour package.

• The action of candles is 4 hours.

The contraceptive cream is squeezed out of the tube into the dispenser container, it is important that no air bubbles form, this reduces the amount of active ingredient in a portion of the contraceptive. Lying on your back, you need to insert the dispenser into the vagina and slowly inject the cream as deep as possible, pressing the plunger.

• The cream starts working immediately and lasts 10 hours.

The duration of the action of the drug does not mean that during all this time you can have sex. Each new sexual intercourse should be accompanied by a dose of Pharmatex. If the instructions are violated, there is a high probability that the spermatozoa will not lose their activity and the egg will be fertilized.

special instructions

It is very important to follow the instructions for use of Pharmatex, since it is often the non-compliance with the rules of use that leads to an unplanned pregnancy. Do not use soap and other cosmetics for washing during the use of this contraceptive.

Soap, even in small quantities, destroys the active ingredient of the drug and makes it inactive. Therefore, wash with detergents cosmetics and you can douche no earlier than 2 hours after the end of sexual intercourse. Prior to this, you can carry out the external toilet of the genital organs with running water.

The drug does not have a teratogenic effect and is not excreted in breast milk, so it can be used during pregnancy (which is inappropriate) and breastfeeding.

Since this contraceptive method does not give absolute guarantees, it makes sense to simultaneously use barrier methods contraception.

Side effects Pharmatex, contraindications

Side effects include local allergic reactions. In this case, one or both sexual partners may experience itching, redness, swelling, rash and burning sensation. However, according to doctors, Pharmatex rarely gives side effects.

Contraindications to the use of the drug are the presence of hypersensitivity to the components of the drug, irritation and injury of the genital organs, the use of other vaginal drugs during this period of time, which can neutralize the action of Pharmatex.

An overdose cannot happen, since the drug is not absorbed into the blood, but is only distributed along the walls of the vagina.

Pharmatex analogues, list of drugs

Pharmatex analogues include:

1. Erotex,
2. Benatex,
3. Gynecoteks,
4. Erocepin-Farmex.

Remember that a doctor's consultation is required, but if you are going to use an analogue of the already prescribed Pharmatex - instructions for use, price and reviews of analogues do not apply and cannot be used as a guide for treatment. When replacing Pharmatex with an analogue, it may be necessary to correct the application scheme.

Pharmatex - tablets, cream or suppositories - which is better?

Choose pills, cream or suppositories Pharmatex can only be decided by the woman herself according to her subjective feelings. However, there are still some nuances in the use of drugs.

For example, Pharmatex vaginal birth control pills are suitable only for those women who have no problems with lubrication. Since if the natural lubricant is weakly secreted, then the tablet is quite difficult to insert deep into the vagina, and besides, there may be problems with its dissolution.

Suppositories have a great lubricating function and are suitable for everyone. Pharmatex cream has a high lubricity, its use is considered more hygienic, since it is not necessary to insert fingers into the vagina, a special dispenser is attached for this. In addition, its action occurs immediately and lasts many times longer compared to tablets and suppositories.