Vitamin C effervescent tablets 1000 mg multivit. Vitamin C. International non-proprietary name or grouping name

Latin name: Acid ascorbicum®
ATX code: A11GA01
Active substance: ascorbic acid
Manufacturer: Hemofarm (Serbia),
Stirolbiopharm (Ukraine)
Pharmacy leave condition: Without recipe

Round yellow dragees with a sweet and sour taste are familiar to everyone since childhood. Parents often replaced sweets with healthy vitamins for sweet teeth. But effervescent tablets, highly soluble in water, can only be used by adults. Despite the fact that now the manufacturer produces such a medicine with different flavors - orange, strawberry, the dose of vitamin C in a unit of the drug is shock - 1,000 mg. This is four times the required daily intake, which helps the body instantly start the immune mechanism in an enhanced mode during a cold.

Indications

The drug is prescribed for the following pathologies and conditions caused by a serious deficiency of vitamin C:

  • Viral respiratory pathologies in acute form
  • Increased mental and physical stress
  • To strengthen immunity
  • In influenza epidemics
  • Asthenia
  • Recovery period after illness
  • long-term chronic infections
  • Addictions: alcohol, nicotine, drugs, drugs
  • stressful conditions
  • Burns and frostbite
  • Pregnancy with more than one fetus
  • Postoperative period
  • Scurvy

Compound

The unit of the product contains 1,000 mg of the main active ingredient - ascorbic isomeric acid and a number of auxiliary components:

  • Sodium carbonate and bicarbonate
  • Sorbitol
  • Acid and lemon flavor
  • Phosphatriboflavin sodium
  • macrogol
  • Povidone
  • Orthosulfobenzimid.

All additional elements are used in the pharmaceutical industry for the manufacture of drugs in solid form and for the ability of solubility. These are fillers, defoamers, stabilizers and preservatives.

Pharmacological properties

First of all, vitamin C is responsible for the normal state of connective and bone tissues. Participates in recovery processes, acts as a coenzyme, which is required for reactions with amino acids. This is a powerful antioxidant, which was first introduced in 1928 by the scientist A. Szent-Györgyi. In the 70s of the last century, chemists investigated and confirmed the theory that high doses of ascorib can protect the body from many diseases, from colds to oncological pathologies.

The substance is indispensable for the synthesis of collagen and the formation of its fibers, which is important for the skin, hair, nails, helps prevent the formation of early wrinkles, baldness. It is not able to be synthesized in the body, but enters the system only with food. It is with malnutrition, improperly organized diets or forced starvation that a person experiences a deficiency of ascorbic acid and is exposed to such a disease as sorbut.

This pathology entails an almost complete loss of the ability to produce collagen, which leads to a reduction in the strength of the connective tissue. First of all, the problem is reflected in the oral cavity - the gums begin to bleed, the vessels become fragile, and a hemorrhagic rash appears. Pain in the extremities is also provoked by a lack of vitamin, and in children the formation of the bone skeleton is disturbed, and anemia develops.

Vitamin C is necessary for the production of essential protein, lipid substances, hormones, trace elements and amino acids:

  • Phenylalanine
  • Tyrosine
  • norepinephrine
  • Histamine
  • folate
  • Iron
  • Proteins
  • Carnitine.

Ascorbinka regulates the hydroxylation of neurotransmitters: serotonin and tryptomine, ensures the full distribution of glucose throughout the cells and its reactions with tricarboxylic acids. It utilizes carbohydrates and improves the absorption of vitamins B1, B2, E, A. The element is engaged in the transport of hydrogen ions, the production of tetrahydrofolates, which is aimed at accelerating regeneration processes. By inhibiting the synthesis of hyaluronidase, it maintains normal capillary permeability and colloidal filling of cellular compounds.

Stimulates the enzymatic activity of proteolytics and the accumulation of glycogen elements in the liver. It also increases the production of prothrombin and controls the detoxification functions of the organ. Also, vitamin C is responsible for the normal separation of bile, the functioning of the thyroid and pancreas. In terms of immunity, the properties of the acid ensure the production of antibodies and interferon. The substance blocks the formation of inflammatory and allergic mediators.

In the process of metabolism, it is transformed into diketogulonic acid. It is excreted by the kidneys by 60%, the rest is eliminated with the intestines. The higher the dose, the faster the metabolites are evacuated. Smoking and drinking alcohol are detrimental to the vitamin.

Release form

Cost: tab. 1000 mg No. 20 - 350-400 rubles.

The drug is presented in the form of yellowish large tablets with a rough surface and a double-sided chamfer. When lowered into water, the solution with lemon filler acquires a pale yellow tint, and with strawberry - pink. The smell is appropriate, the taste is sweet and sour, quite pleasant. Very convenient packaging - the medicine is packaged in a cylindrical shape made of polypropylene and cardboard with a tight-fitting cap. The lid has a special tongue, so it is easy to uncork. The box is bright, contains a tube with 20 tablets of ascorbic acid 1,000 mg and instructions.

Application methods

Effervescent medicine is not used for prophylaxis in shock dosages. With a serious deficiency, it is prescribed 1 tablet once a day. After restoring the concentration in the patient's body, they are transferred to lower doses - 250 mg twice a day for two weeks.

Use in pregnancy

In the first trimester, the drug is strictly prohibited. In 2 and 3 - the daily requirement is 60 mg, but it should be borne in mind that when taking high doses, the infant may develop a withdrawal syndrome. Therefore, for prevention, it is better to take 250 mg of the drug. An exception is the state of severe deficiency in multiple pregnancies. During lactation, high doses are also not recommended.

Contraindications

Do not prescribe a vitamin medication for the following pathologies and conditions:

  • Diabetes
  • Nephropathy oxalate
  • Thalassemia
  • Sideroblastic type anemia
  • Pigmentary cirrhosis
  • Glucose deficiency
  • oxalosis
  • The presence of stones in the kidneys
  • Nephrolithiasis
  • Pediatric patients
  • Pyorrhea
  • Infectious lesions of the gums
  • Proliferating cancer and the development of metastases.

Combinations with other drugs

It should be borne in mind that vitamin C is able to show both antagonism and synergy with various drugs:

  • Increases the concentration of tetracyclines and penicillins
  • Improves the bioavailability of ethinyl estradiol
  • Reduces the effectiveness of anticoagulants and heparin
  • Absorption worsens when taken with Aspirin
  • Salicylates and sulfonamides increase the risk of excess salt accumulation
  • Iron supplements are absorbed faster
  • Alkaloids are eliminated more slowly
  • Cholinolytics and corticosteroids contribute to the depletion of the ascorbic acid reserve.
  • The therapeutic effect of antipsychotics and tricyclics is deteriorating
  • Barbiturates increase the rate of excretion of vitamin C.

Adverse reactions

Most people tolerate the drug well, but in some cases it can have negative effects:

  • On the part of the digestive system: irritation of the gastric mucosa, nausea, gag reflex, ulceration
  • Endocrine system: hyperglycemia, glycosuria
  • Urethral organs: pollakiuria, nephrolithiasis, damage to the glomeruli.
  • Nervous system: overexcitability, sleep disturbance
  • Heart and blood vessels: microangiopathy, hypercoagulability, arterial hypertension
  • Allergic manifestations on the skin: itching, redness, peeling.

Since vitamin C can have a stimulating effect on the synthesis of corticosteroids, it is important to monitor the functions of the adrenal glands and pancreas during administration in order to monitor insulin levels. With an increased iron content in the body, high doses of ascorbic acid are not prescribed.

It should be borne in mind that the vitamin is a reducing agent, therefore, it can change the rheological properties of the blood, which will affect the results of biological tests during diagnosis. Possible violation of zinc and magnesium metabolism, retention of sodium compounds, which causes accumulation of fluid in the body and swelling.

Overdose

Exceeding the recommended amount leads to aggravation of adverse reactions and the development of serious complications. The patient may begin dyspeptic and nervous disorders. In this case, it is necessary to urgently stop taking the drug, the doctor prescribes symptomatic treatment and forced diuresis.

Storage rules

Tableted vitamin product can be used for 24 months, provided that the tube is protected from light and moisture. Access to children must be restricted. The temperature of the contents of the package is from 20 0 to 25 0 С.

Analogues

There are a number of drugs that are also made in the form of effervescent tablets and contain vitamin C.:

Celascon

Manufacturer: Zentiva (Slovakia)

Price: tab. 500 mg No. 30 - 150-200 rubles.

The medication is a composition with an orange smell and taste. These are pinkish effervescent tablets with marble veins and a rough surface that dissolve quickly in water. The box contains instructions and a tube of 30 units. The main active ingredient is ascorbic acid, which is necessary for the formation of collagen fibers and the preservation of the connective tissue structure. Participates in lipid and protein synthesis, is responsible for stimulating enzyme mechanisms, helps to improve immunity. The substance is able to increase the absorption and absorption of iron, therefore it is actively used to treat anemia.

In addition, the remedy is prescribed for the prevention of vitamin deficiency, it is suitable for maintaining the operation of all systems during pregnancy and lactation. Effective during the rehabilitation period after surgical interventions. It is used as part of complex therapy for respiratory pathologies, for healing wounds and skin lesions. Contraindicated in kidney failure, leukemia, malignant tumors in the stage of metastasis. To take, you need to dissolve 1 tablet in 150 ml of water, drink once a day for 10-15 days.

Advantages:

  • Convenient packaging
  • Acceptable price.

Flaws:

  • Rarely found in pharmacies
  • Do not take with damage to the gastric mucosa.

Ascovit

Manufacturer: Natur Product (Netherlands)

Price: tab. 1000 mg No. 10 - 160-200 rubles.

This preparation contains vitamin C in the form of round large white tablets. They are available in several versions - convenient tubes made of polypropylene and cardboard or in paper caramels, like sweets. The composition has a wide variety of tastes - strawberry, lemon, orange, pineapple. They dissolve easily in water. It is enough to dip one tablet in 150 ml of liquid - and a tasty, aromatic drink will be ready. Great for boosting your immune system and fighting off colds and flu.

It is prescribed after surgery, prolonged use of antibiotics for tuberculosis, for the treatment of alcoholism and the restoration of missing reserves in the body. The drug helps to maintain systems after fasting and diets. For prevention, the composition is prescribed at a dosage of 500 mg per day, for treatment - 1,000 mg. It is best to take it after meals.

Advantages:

  • Pleasant taste
  • Dissolves quickly in water.

Flaws:

  • Should not be given to children
  • Contraindicated in the 1st trimester of pregnancy.

Every day a person needs additional sources of vitamin substances, since unfavorable environmental conditions of life, constant stress, and an irrational approach to nutrition negatively affect their absorption by the body. Because of this, the internal organs and their systems cease to function normally. Vitamin C comes in several forms. According to scientific data, effervescent tablets are the best option, suitable not only for children, but also for adults.

Instructions for use

Effervescent tablets are produced by a Serbian pharmaceutical company, distributed by a representative office from Croatia. The main active ingredient in the preparation is ascorbic acid, which is the strongest antioxidant.

Release form, composition

Effervescent Vitamin C is available in tablets designed to be dissolved in a liquid. They have a pale yellow or yellow tint and are chamfered on both sides. Their surface is rough. The drug is available in two versions. In one amount of ascorbic acid is 1000 mg, in the other - 250 mg. Tablets are offered packed in tubes, which in turn are offered in cardboard boxes. One bottle contains 20 pops.

Auxiliary substances in the preparation are:

  • sodium bicarbonate;
  • sodium carbonate;
  • "lemon" (citric acid);
  • sucrose;
  • flavoring with an orange smell;
  • riboflavin sodium phosphate;
  • sodium saccharin;
  • macrogol;
  • sodium benzoate;
  • povidone.

Auxiliary elements in the composition of the tablets are aimed at enhancing the action of the main substance - ascorbic acid.

Beneficial features

The main benefits of sour for adults and children are:

  • strengthening the body's defenses;
  • increasing the ability to resist pathogens of viral infections;
  • cleansing the vessels, giving them additional elasticity, permeability;
  • removal of cholesterol plaques;
  • strengthening the nervous system, preventing the development of depressive conditions;
  • stimulation of the production of sex hormones;
  • increasing the absorption of iron by the digestive tract;
  • improving the functioning of the hematopoietic system.

Despite the benefits of using vitamin C, you should consult your doctor before taking it. In any case, there are certain indications for its use, as well as contraindications that cannot be ignored.

Indications for appointment

An indication for the appointment of an agent containing 1000 mg of ascorbic acid is the need to eliminate the state of hypovitaminosis of the specified element. A preparation containing 250 mg of a substance has slightly more indications for prescribing. These include:

  • prevention/treatment of beriberi, hypovitaminosis C;
  • heavy loads mentally, physically;
  • complex therapy of colds, SARS, influenza;
  • exhaustion;
  • recovery from severe illnesses;
  • pregnancy;
  • Addison's disease;
  • radiation sickness;
  • hepatitis;
  • cholecystitis.

In addition, it is important to take effervescent tablets for rheumatoid arthritis, as well as various bleeding, nasal, pulmonary, uterine. Before starting use, it is important to consult with a specialist or study the instructions for use of the drug in detail.

Contraindications

Despite the enormous benefits of vitamin C, there are certain contraindications to its use in an effervescent form. These include:

  • individual intolerance to ascorbic acid, other components of the drug;
  • predisposition to the formation of blood clots;
  • diabetes;
  • urolithiasis disease;
  • belonging to the age group under eighteen;
  • hemosiderosis;
  • hemochromatosis;
  • thalassemia;
  • fructose intolerance;
  • a severe form of diseases that disrupt the functioning of the renal system.

Long-term use of drugs is also contraindicated. For this reason, it is important that the specialist establishes the exact number of days when they need to be used. A second course of admission is prescribed only after consulting a doctor.

How to use?

It is recommended to use drugs after meals. Their minimum dosage per day is one tablet dissolved in 200 ml of liquid. It is strictly forbidden to dissolve the pops, keep them in your mouth for a long time, and also chew them. In the event that it is necessary to treat a condition caused by a lack of vitamin C, one tablet containing 1000 mg of the substance per day is prescribed. In the prevention of hypovitaminosis C, a drug with a dosage of the main element of 250 mg in the amount of one or two pops is used.

During pregnancy and lactation

During pregnancy, a woman needs more ascorbic acid, since it is also necessary for the fetus. For this reason, experts prescribe taking effervescent tablets for ten to fifteen days. In this case, the dosage of "ascorbic acid" should not be higher than 250 mg. Why can't you take the drug all the time? The fetus may develop dependence on the beneficial substance, due to which, after its withdrawal, development may be impaired.

During lactation, it is not recommended to use pharmaceutical preparations at all. It is much better to enrich the diet of a nursing woman with foods containing sufficient amounts of vitamin C. The amount of acidic vitamin per day for a nursing woman should not exceed 80 mg. Otherwise, the baby may develop an allergy to the specified substance.

Side effects

Side effects usually occur when the dosage prescribed by the doctor is exceeded. These include:

  • headache;
  • sleep disorders;
  • increased excitability, disinhibition;
  • irritation of the mucous membrane of the digestive tract;
  • hyperglycemia;
  • glycosuria;
  • decrease in the permeability of capillary walls;
  • allergic reactions in the form of skin rash, hyperemia;
  • hypervitaminosis;
  • violation of metabolic processes.

If you have one or more of these symptoms, you should consult a specialist. Perhaps the withdrawal of drugs will be enough to normalize the condition, however, there are cases when an overdose becomes chronic and then symptomatic treatment is required.

special instructions

It is worth noting that when using effervescent tablets, it is important to control your diet and reduce the amount of food consumed: cabbage, citrus fruits, herbs, tomatoes, currants, potatoes. People who have an increased amount of iron in the blood should take the drug in a minimal amount. In addition, both forms of pops should be used with caution when diseases such as:

  • infectious gum disease;
  • phenomena of hemorrhage;
  • hematuria;
  • hemorrhages in the retina;
  • violations of the protective system;
  • depressive disorders not associated with a lack of vitamin C.

Before passing laboratory tests, it is important not to take ascorbic acid, since its presence in the body can distort the results. For better preservation of drugs, it is important to store them correctly, that is, place them in dark places where children cannot reach. In this case, the air temperature in the room should not exceed 25°C.

Interaction with other drugs

Before you start using vitamin C in tablets intended for dissolution in water, you should notify your doctor about taking certain medications. So, for example, its combined use with birth control pills will lead to an increase in the concentration of the latter in the blood. At the same time, the amount of a valuable substance in the body will decrease.

If "ascorbic acid" is taken together with aspirin, it is not absorbed in the stomach, it is immediately excreted by the renal system. At the same time, the excretion of aspirin from the human body slows down. It is advisable to take iron-containing preparations together with an acidic vitamin, since it favorably affects their absorption. You should not combine taking atropine, isoprenaline with vitamin C, as this will lead to a rapid heartbeat.

Why are effervescent tablets a priority?

It is known that the human body is not able to independently synthesize acidic vitamin. For this reason, it is important to replenish its shortage in a timely manner. Some begin to adjust the diet, enriching it with foods with a high content of ascorbic acid in them. However, there are often times when this is not enough. Then you have to resort to pharmaceutical preparations.

Experts used to prescribe the substance in tablets, syrup form, but recently everyone agrees that pops are the best, more effective option. The advantages of using this form of release of the vitamin are:

  • rapid assimilation by the human body;
  • safety;
  • pleasant taste, which is important when taking the drug by children.

It is known that the effervescent form of vitamin C is absorbed by the human body five times faster than the tablet form. In addition, it is absorbed much faster, which does not allow it to harm the mucous membrane of the gastrointestinal tract. For this reason, the drug is not contraindicated in people suffering from gastritis, gastric ulcer, duodenal ulcer.

About the benefits ascorbic acid (vitamin C) everyone knows. Many people during the off-season try to eat more products that contain it. As a rule, high hopes are placed on fruits and berries. But, unfortunately, if these are not self-grown fruits, vegetables and berries, then they contain a minimum amount of vitamins, they are not ripe, they are used for growing chemicals, and during long-term storage they even lose what they have.

To maintain immunity and vitality in the autumn-spring period, I always take ascorbic acid prophylactically. I buy it both in powders and in effervescent tablets and small dragees.

Of the effervescent options, I like it the most ascorbic acid manufacturer Hemofarm. This manufacturer produces effervescent tablets in two versions: 250 mg and 1000 mg per tablet.

Externally, the tablets are no different, they have the same size and their solution also has the same citrus taste. (The packaging in the photo is slightly different because the company has changed the packaging, and now both dosages look like the one for 1000 mg.)


The drug is available in the form of soluble tablets of a sufficiently large diameter, having the classic smell of ascorbic acid with an admixture of citrus aroma. Tablets are packed in a metal tube with a plastic cap, 20 pieces, and then in a cardboard box.


The cost is from 130 rubles for a dosage of 250 mg, up to 250 rubles for a dosage of 1000 mg. I sometimes take a large dosage and then just break it in about half. It is clear that the dosage in each half is not exactly 500 mg, but approximately, but it turns out cheaper, and I don’t overdo it with the amount of acid.


VITAMIN C plays an important role in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration; participates in the synthesis of corticosteroids, collagen and procollagen; normalizes capillary permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid, increases the body's resistance, which is apparently associated with the antioxidant properties of ascorbic acid.

The disadvantage is manifested in rapid fatigue, bleeding gums, in a general decrease in the body's resistance to infections, with advanced hypovitaminosis C, scurvy may appear, which is characterized by loosening, swelling and bleeding of the gums and tooth loss, small subcutaneous hemorrhages. In case of an overdose, violations of the liver and pancreas are possible.


Despite the fact that this seemingly simple vitamin has a significant effect on all processes in the human body, it is not worth taking it in huge dosages, even if it is a water-soluble substance and is freely excreted from the body in excess. If it turns out to be too much, then it will have time to have a negative impact on the body even before the kidneys get rid of it.


There are certain indications for taking ascorbic acid.

INDICATIONS:

For tablets containing 1000 mg of ascorbic acid

- treatment of vitamin C deficiency.

For tablets containing 250 mg ascorbic acid

Treatment and prevention of hypo- and avitaminosis C, incl. due to the state of increased need for ascorbic acid with:

- increased physical and mental stress;

- in the complex therapy of colds, SARS;

- in asthenic conditions;

- during the recovery period after illness.

- pregnancy (especially multiple, on the background of nicotine or drug addiction).


It is also necessary to remember that this is still a drug and its excessive intake into the body may be contraindicated, and side effects may also develop.

CONTRAINDICATIONS FOR USE:

- children's age up to 18 years (for this dosage form);

With prolonged use in high doses (more than 500 mg): diabetes mellitus, hyperoxaluria, nephrolithiasis, hemochromatosis, thalassemia;

- hypersensitivity to the components of the drug

FROM caution: diabetes mellitus, deficiency of glucose-6-phosphate dehydrogenase, hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, oxalosis, urolithiasis.


I try not to take ascorbic acid in any form, and even more so in the form of effervescent tablets during the period of exacerbation of my chronic gastritis, so as not to expose the gastric mucosa to excessive acid, which is already enough. And in general I try to drink vitamin C not on an empty stomach, so as not to suffer from heartburn later. It is generally desirable for people with erosive gastritis and those suffering from gastric and duodenal ulcers to refrain from taking ascorbic acid in this form.

In addition, you need to remember that the pill, no matter how funny it sounds, must be dissolved in water, and not dissolved in the mouth. Otherwise, it can lead to damage to the enamel of the teeth and even to the development of stomatitis with the formation of ulcers.


The tablets dissolve in water quite quickly, literally within 3-4 minutes, and a greenish-yellow solution is formed with a characteristic smell of vitamin C and a fruity-citrus taste. A kind of Fanta.



Dosages will depend on how much this drug is not enough in the body, that is, it is prevention of hypovitaminosis or already treatment.

Dosing regimen:

The drug is taken orally after a meal. 1 tablet is dissolved in a glass of water (200 ml). Tablets should not be swallowed, chewed or dissolved in the mouth.

Treatment for vitamin C deficiency: 1000 mg / day.

Treatment and prevention of hypo- and avitaminosis C: 250 mg 1-2 times / day.

At pregnancy prescribe the drug in the maximum daily dose - 250 mg for 10-15 days.


It should also be remembered that if a person simultaneously takes other vitamins containing ascorbic acid, then you need to control the dosage more carefully so as not to exceed the daily requirement.


It is extremely difficult to prove the positive effect of ascorbic acid, like any other vitamins, on the body. because all processes occur at the cellular level. I can’t say if I had more or less colds, whether it really makes my skin feel better, but I would like to hope that it is easier for the body to survive the cold season with additional intake of vitamin C.

This spring, my sick husband recovered much faster on vitamin C than last time. So we still managed to observe the effect of the drug.

I recommend ascorbic acid in effervescent tablets, but with certain reservations about the dosing regimen.

Vitamin C-1000 / Vitamin C-1000, 100 capsules, - a natural source with a high content of vitamin C.

Ascorbic acid, an organic compound related to glucose, is one of the main substances in the human diet, which is necessary for the normal functioning of connective and bone tissue, and is an antioxidant. Only one of the isomers is biologically active - L-ascorbic acid, which is called vitamin C. In nature, ascorbic acid is found in many fruits and vegetables. Vitamin deficiency of ascorbic acid leads to scurvy.

Citrus bioflavonoids (Citrus plants bioflavonoids) are natural phenolic compounds, the source of which is the peel of citrus fruits. They regulate the permeability of the walls of blood vessels and improve their elasticity, preventing sclerotic lesions.

Due to the antioxidant effect, dietary supplements based on citrus bioflavonoids slow down aging and prevent the occurrence of malignant neoplasms. Such drugs have anti-inflammatory, anti-allergic, antiviral and antitumor effects.
Citrus bioflavonoids (Citrus plants bioflavonoids) are involved in cellular respiration as catalysts, accelerating physiological processes. They can be used to prevent atherosclerosis and atherothrombosis.

Rutin is a remedy for reducing vascular permeability, improving microcirculation and normalizing metabolic processes in the vascular wall. The active substance of Rutin is rutoside, filling the deficiency of vitamin P, reduces swelling and inflammation, and also strengthens the walls of blood vessels. Rutin's action extends to capillaries and veins. Rutin reduces swelling of the lower extremities in patients with pathology of the outflow of lymph (lymphostasis), chronic venous insufficiency, relieving pain and numbness of the extremities (paresthesia).

Vitamin C-1000 / Vitamin C-1000 composition:

One tablet of Vitamin C-1000 contains:

  • Vitamin C (as ascorbic acid) 1000 mg
  • Citrus Bioflavonoids 100 mg
  • Rutin 25 mg

Vitamin C-1000 / Vitamin C-1000 functions:

o Inhibits the release and accelerates the degradation of histamine, inhibits the formation of prostaglandins and other mediators of inflammation and allergic reactions.
o Regulates immunological reactions (activates the synthesis of antibodies, interferon), promotes phagocytosis, increases the body's resistance to infections.
o Improves bile secretion, restores the exocrine function of the pancreas and the endocrine function of the thyroid.
o Activates proteolytic enzymes, participates in the exchange of aromatic amino acids, pigments and cholesterol, promotes the accumulation of glycogen in the liver. Due to the activation of respiratory enzymes in the liver, it enhances its detoxification and protein-forming functions, increases the synthesis of prothrombin.
o Maintains the colloidal state of the intercellular substance and normal capillary permeability (inhibits hyaluronidase).
o Regulates the transport of H + in many biochemical reactions, improves the use of glucose in the tricarboxylic acid cycle, participates in the formation of tetrahydrofolic acid and tissue regeneration, the synthesis of steroid hormones, collagen, procollagen.
o It has antiplatelet and pronounced antioxidant properties.
o Participates in the metabolism of phenylalanine, tyrosine, folic acid, norepinephrine, histamine, iron, carbohydrate digestion, lipid synthesis, proteins, carnitine, immune responses, serotonin hydroxylation, enhances the absorption of non-heme iron.
o Participates in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration; increases the body's resistance to infections, reduces vascular permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid.
o Inhibits glycosylation of hemoglobin, inhibits the conversion of glucose into sorbitol.
o Converts ferric iron to ferrous, thereby contributing to its absorption.
o Stimulates the synthesis of interferon, therefore, is involved in immunomodulation.
o Vitamin C is essential for detoxification. Restores ubiquinone and vitamin E.
o Ascorbic acid is involved in the conversion of cholesterol into bile acids.
o Participates in the formation of collagen, serotonin from tryptophan, the formation of catecholamines, the synthesis of corticosteroids.
o It has a stress-protective, tranquilizing, tonic and other effects.

Vitamin C-1000 / Vitamin C-1000 indications for use:

  • In cases of increased bleeding (hemorrhagic diathesis), hemorrhoids, allergic inflammation of the walls of blood vessels (capillarotoxicosis), hypertensive, diabetic, atherosclerotic retinopathy; inflammatory diseases of the internal cavities of the heart caused by the presence of microbes in the blood (septic endocarditis); lymphostasis; in case of kidney disease accompanied by edema (glomerulonephrosis); rheumatic disease; radiation sickness; in cases of pain and swelling due to injuries.
  • With chronic venous insufficiency, accompanied by trophic disorders, swelling, ulcers.
  • With edema, dizziness, diseases of the inner ear.
  • Diseases characterized by increased vascular permeability, glaucoma, allergies, diathesis, infectious diseases.
  • Skin diseases.
  • Influenza and acute respiratory infections.
  • Hypertension and other cardiovascular diseases.
  • Pain in the joints (osteoarthritis, osteochondrosis, etc.).
  • Improvement of skin properties (whitening and tightening effects).
  • Psycho-emotional stress and great mental stress.

Ascorbic acid, or vitamin C, is an affordable remedy that is easy to buy without a prescription at any pharmacy. Regular use protects the body from infections, stimulates metabolism and improves skin condition. A sufficient amount of the vitamin enters the body with a balanced diet, but in winter, in conditions of a shortage of fresh fruits and vegetables, the risk of hypovitaminosis C increases. In order to avoid this condition, you can buy vitamin tablets.

Ascorbic acid, or vitamin C, is an affordable remedy that is easy to buy without a prescription at any pharmacy.

Release form and composition

Release form - effervescent tablets, 20 pcs. packaged. 1 tablet contains 1 g of the active ingredient - vitamin C. Additional components: sodium carbonate, sodium saccharinate, sodium benzoate, sodium bicarbonate, povidone-K30, sodium riboflavin phosphate, macrogol 6000, sorbitol. Contains citric acid and citric acid flavor.

Pharmacological action of Ascorbic acid 1000

Vitamin C has an effect on redox reactions in cells. Has an antioxidant effect - neutralizes the action of free radicals; activates metabolism, affects tissue regeneration.

Vitamin is vital for a person, it is not synthesized by the body on its own, it comes with food - berries, fruits, vegetables, nuts. With a lack of a substance, scurvy develops - a disease characterized by fragility of blood vessels and a decrease in the protective forces of immunity.

The presence of vitamin C contributes to the synthesis of substances important for the body - it is involved in the formation of corticosteroids, collagen, and the neurotransmitter serotonin. It has an effect on the restoration of vitamin E and ubiquinone (coenzyme Q10). Provides uptake of glucose by cells.

Vitamin affects the functions of the immune system - activates the synthesis of interferon. In the presence of ascorbic acid in humans, the need for vitamins A, B1, B2, E, folic and pantothenic acids is reduced.

With violations of the digestive system, the use of alkaline drinks, vegetable and fruit juices, the absorption and assimilation of the vitamin is reduced.

After administration, the maximum plasma concentration of the substance is observed after 4 hours. Normally, the amount of ascorbic acid in the blood is about 10-20 μg / ml, with the use of the recommended doses of the substance, approximately 1.5 g is stored per day. Drinking alcoholic beverages and smoking contribute to the destruction of vitamin C and reduce the reserves of the substance in the body.

Indications for use Ascorbic acid 1000

Contraindications

Do not take in case of hypersensitivity to any of the components in the composition.

In the case of a long course and in high doses, diseases become a contraindication: diabetes mellitus, kidney stones, oxalosis, Cooley's anemia, hemochromatosis. With these diagnoses, sideroblastic anemia and deficiency of glucose-6-phosphate dehydrogenase, the vitamin should be used with caution, even if the minimum dosage is observed.

How to take Ascorbic Acid 1000

Do not swallow or dissolve the tablets - they are taken orally, previously dissolved in a glass of water. This should be done after meals.

With vitamin deficiency, the daily dose is 1000 mg (1 tablet).

Daily intake in order to prevent vitamin deficiency is 250 mg 1 or 2 times.

Side effects

In case of hypersensitivity to the components, an allergic reaction may occur. Long-term use in high doses can lead to hypervitaminosis, metabolic disorders, insomnia and headache, feeling hot, excitation of the central nervous system.

There may be irritation of the gastrointestinal mucosa, inhibition of pancreatic function, impaired renal function, and a decrease in vascular permeability.

Overdose

With prolonged use of the drug in an amount of more than 1 g per day, an overdose is possible. It is manifested by heartburn, nausea, diarrhea, flatulence, abdominal cramps, irritation of the gastrointestinal mucosa. Urination is increased, the amount of sugar in the blood falls, there are problems with sleep, the person becomes more irritable.

Overdose therapy consists of forced diuresis and treatment of symptoms.

special instructions

Caution should be exercised in certain conditions.

Use during pregnancy and lactation

The minimum required amount of vitamin during pregnancy is 60 mg, while breastfeeding - 80 mg.

When prescribing ascorbic acid to pregnant women, the dose does not exceed 250 mg per day, and the course of use lasts no more than 2 weeks.

Application in childhood

Ascorbic acid at a dosage of 1 g per day is prohibited for use in childhood. Children should take vitamin C at a lower dosage.

drug interaction

Joint use with acetylsalicylic acid and hormonal contraceptives reduces the absorption of vitamin C, and barbiturates accelerate its excretion.

Reduces the effect of isoprenaline, anticoagulants and some antipsychotics.

Long-term therapy with corticosteroids, salicylates, quinolones and calcium chloride reduces vitamin C stores.

When using the vitamin, the level of oral contraceptives in the blood decreases, the excretion of acids slows down and the transportation of drugs with an alkaline reaction is accelerated. Increases the amount of salicylates in the blood, which can lead to the development of crystalluria. Improves intestinal absorption of drugs containing iron.

Terms and conditions of storage

Storage temperature – +15…+25°C. It should be kept out of the reach of children. Protect from direct sunlight and high humidity. Tablets are suitable for use for 2 years from the date of manufacture.

Vitamin C.

Terms of dispensing from pharmacies

No prescription required to purchase.

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