Sub Simplex - official * instructions for use. Method of application and dose. Can there be an allergy to the drug

SAB simplex for newborns is one of the most safe medicines from colic. The action of the drug is aimed at the cause of flatulence, without interfering with the biochemical processes of digestion. Drops SAB simplex from colic naturally remove gases from the body.

In this article, we will consider why doctors prescribe Sub Simplex, including instructions for use, analogues and prices for this drug in pharmacies. REAL REVIEWS people who have already used Sub Simplex can be read in the comments.

Composition and form of release

Sub Simplex is available in the form of a suspension for oral administration. The drug is sold in glass bottles with a drip device (25 drops in 1 ml). Each bottle (30 ml of the drug) is placed in a cardboard box.

The active ingredient of the drug is simethicone, which is supplemented with full membership medicinal product the following complex of substances: hypromellose, sorbic acid, carbomer, polyglycostearic acid esters, sodium citrate hydrate, sodium benzoate, citric acid monohydrate, sodium saccharinate and cyclomate, raspberry and vanilla flavors, as well as necessary quantity purified water.

Clinico-pharmacological group: a drug that reduces flatulence.

What helps Sub simplex?

Indications for the use of the drug SAB simplex:

• before hardware diagnostics of the gastrointestinal tract: ultrasound, FGDS, radiography, CT, MRI;
• in case of poisoning detergents(surfactant);
• bloating in the intestines of a physiological nature in infants. This medicine does not cure infectious diseases and enzymatic disorders, which are also characterized painful sensations in the abdomen and bloating, from which the child starts crying.

Before buying this drug for a child, consult a pediatrician. Only he will be able to find out the real reason for the restless behavior of the baby, tell the diagnosis and prescribe the right treatment.

Pharmacological effect

The main active component of the suspension Sub simplex simethicone belongs to surface-active compounds and has the properties of a defoamer. Due to these properties, it reduces the surface tension of gas bubbles, leads to their rupture, while the released gas is absorbed by the walls of the intestine or excreted into the lower sections. digestive tract due to peristaltic movements.

The therapeutic effect of the drug is to reduce the volume of gas in the intestines. During an x-ray examination hollow organs digestive system, it contributes to a more even distribution contrast agent on the mucous membrane and obtaining reliable result research.

Instructions for use

How to take the drug correctly? The dose of the drug depends on the age of the patient:

• According to the instructions Sab simplex with increased gas production for newborns and children who are on artificial feeding, add 15 drops (0.6 ml) of the suspension. The drug mixes well with other liquids (including milk).
• children before school age add 15 drops (0.6 ml) during or after meals, and if necessary, an additional 15 drops at night.
• School age children single dose is 20-30 drops (0.8-0.12 ml), for adults - 30-45 drops (1.2-1.8 ml), which the dose is taken every 4-6 hours. If necessary, it is possible to increase the single dose.

The duration of use depends on the clinical situation, if necessary, long-term therapy is possible. When passing the study, the drug can be prescribed at a dosage of 3 teaspoons the day before the procedure. For ultrasound, the patient drinks 15 ml of the drug the day before the study, the same dose is taken three hours before the procedure.

Contraindications

A contraindication to taking Sub Simplex is:

1. Intestinal obstruction.
2. Obstructive diseases of the gastrointestinal tract.
3. Increased individual sensitivity to the active substance (simethicone) or any of the constituent components of the drug.

Side effects

While taking Sab Simplex, allergic reactions may develop.

Analogues Sub simplex

Structural analogues for the active substance:

• Antiflat Lannacher;
• Bobotic;
• Disflatil;
• Meteospasmil;
• Simethicone;
• Simicol;
• Espumizan;
• Espumizan 40;
• Espumizan L.

Attention: the use of analogues must be agreed with the attending physician.

Prices

The average price of SAB SIMPLEX, suspension in pharmacies (Moscow) is 290 rubles.

Terms of dispensing from pharmacies

The drug is approved for use as a means of OTC.

For newborns - a drug that effectively destroys gas bubbles in the intestinal lumen. It also contributes to a decrease in the level of their education. The gases released from their shell are either successfully and painlessly absorbed by the intestinal walls, or excreted from the body in the process of peristalsis. Thus, after taking, it is possible to significantly reduce the degree of stretching of the intestinal wall, which succumbed to the pressure of gas bubbles.

Does not affect the ability of a person to drive a vehicle / machinery.

According to research results, no therapeutic effect if needed to relieve colic in infants or older children.

Do not use the drug after the expiration date.

Overdose

Doesn't have cumulative action does not accumulate in the body. Therefore, cases of overdose were not recorded. If mistakenly received large dose the drug, you need to contact your doctor .. A medicine is produced in syrup, which can be used to eliminate bloating, constipation, restore intestinal microflora.

Terms and conditions of storage

Keep out of the reach of children/animals, at temperatures environment no higher than +25 degrees.

From the date of manufacture, an unopened vial can be stored for 36 months.

Implementation conditions

The drug is sold without a prescription. Before purchasing and using the medicine, a doctor's consultation is required.

The price of the drug

The cost of the drug is an average of 281 rubles. Prices range from 249 to 348 rubles

Intestinal colic in newborns is considered normal and are explained by the immaturity of the digestive system.

Production of enzymes necessary for cleavage nutrients(fats, carbohydrates and proteins) will be sufficient to provide normal digestion only by 4-6 months - until this time, the baby may be disturbed by increased gas formation, flatulence, intestinal spasms and colic.

To combat these phenomena, you can use proven methods: heat on the stomach, massage, special gymnastics, herbal teas. In the absence of the effect of the above measures, the doctor may advise the use of medications with carminative action. One of these drugs is "Sab Simplex" - a remedy for the treatment of functional gastrointestinal disorders, which can be used from the first days of a baby's life.

As the main active ingredient in the production of "Sub Simplex" is used organic compound, consisting of silicon and carbon molecules - simethicone. This is a substance that prevents the formation of gas bubbles and releases already accumulated gas, which is absorbed by the intestinal walls or excreted from the intestinal sections with the help of peristaltic contractions.

Simethicone does not react with chemical compounds and substances and removes the resulting increased gas formation foam naturally, splitting it into gas and water molecules.

The use of the drug "Sab Simplex" in newborns allows you to achieve the following therapeutic effect:

• reducing the number of gas bubbles in the intestines and preventing their fermentation;
• elimination of intestinal spasm;
• muscle relaxation abdominals by foam suppression.

The medicine is available in the form of a suspension with a faint taste of raspberries and vanilla (vial volume - 100 ml).

When is the remedy prescribed?

The main indication for the appointment of "Sub Simplex" in infancy- intestinal colic caused by functional disorders in the work of organs gastrointestinal tract.

The tool is used to eliminate unpleasant symptoms(flatulence, bloating, colic, increased gas formation), but does not replace the main treatment, if necessary.

The pediatrician may prescribe a prophylactic reception of "Sub Simplex" to the baby, if, according to medical indications required diagnostic measures organs of the gastrointestinal tract. These include:

• radiography;
• ultrasound diagnostics;
• esophagogastroduodenoscopy.

Application carminative drugs in the period of preparation for these studies, it helps to eliminate gas bubbles, colic, which can spoil the image quality and affect the diagnostic result.

Important! "Sab Simplex" can be used as an auxiliary component in therapy acute poisoning detergents.

Instructions for use: dosage

To eliminate increased gas formation and colic, newborns should be given 15 drops of the drug in each feeding. If the child is receiving artificial nutrition, the suspension can be added to the bottle (be sure to shake well before feeding).

Babies who are on breastfeeding, "Sub Simplex" can be given with a spoon or instilled from a pipette. It is better to do this before feeding, so that the child feels hungry and does not refuse the medicine.

If the child is already 1 year old, the dosage regimen of the drug does not change, but you can additionally give 15 drops of the suspension at bedtime to eliminate difficulty falling asleep associated with pain.

Note! For children over 6 years of age and adolescents under 15 years of age, the dosage will be 20-30 drops to be taken every 4-6 hours. Adolescents over 15 years of age are given the medicine in the same dosage as adult patients - 30-45 drops.

The duration of treatment depends on the severity of the symptoms. It is necessary to continue the use of the drug until the complete disappearance of painful symptoms. If necessary, it is possible long-term use suspensions (only after consulting a doctor).

Preparation for research

If the child is scheduled for a gastrointestinal examination, the doctor may recommend taking "Sab Simplex" for more exact result. The dosage regimen for children under one year old is calculated individually and depends on many factors: the weight of the child, age, existing diseases. Standard recommendations for the dosage of the drug are as follows:

• preparation for x-rays - 24 hours before the procedure, take from 15 to 30 ml of the drug (preferably in the evening);
• preparation for ultrasound - 15 ml (3 teaspoons) 24 hours and 3 hours before the examination;
• preparation for endoscopic manipulations - 2.5-5 ml immediately before the procedure.

During endoscopic examination a single administration of another dose of the drug is allowed, if necessary.

poisoning

In case of poisoning with detergents minimum dose the drug is 5 ml (1 teaspoon). After taking the drug, it is necessary to show the child to a specialist to assess the severity of the poisoning and the condition of the baby.

Contraindications and side effects

"Sub Simplex" should not be taken if the baby is diagnosed with obstructive diseases of the gastrointestinal tract. Absolute contraindication is intestinal obstruction- a condition in which the movement of digested food through the digestive tract is disturbed.

The use of the product should be discontinued if the child shows signs of allergy or intolerance active ingredient or ancillary components.

Side effects during treatment are extremely rare. AT exceptional cases rash, itching and other allergy symptoms may appear, in which you should immediately consult a doctor who prescribed the treatment.

Is it possible to overdose in newborns?

Cases of overdose this moment not registered. If you accidentally exceed the recommended dose specific treatment the patient is usually not required, since the agent is not absorbed into the systemic circulation and acts only in the intestines. If the dose has been exceeded several times, it is necessary to show the child to the pediatrician.

Interaction with other drugs

Simethicone does not enter into chemical interaction with substances and elements, therefore it can be used simultaneously with any drugs.

How long will the result appear?

"Sub Simplex" begins to act 10-15 minutes after ingestion. The achieved effect lasts from 4 to 6 hours.

What can be replaced?

The absolute analogue of "Sab Simplex" with the same active ingredient is the drug "Espumizan". But there is a significant difference between the drugs, which lies in the dosage: 1 ml of Espumizan contains only 8 mg of simethicone, while Sub Simplex contains 69.19 mg of active ingredient per 1 ml. For this reason, "Sub Simplex" has several advantages:

• the bottle is enough for a longer course of administration;
• the effect after application comes faster;
• one dose requires less drug, which is convenient for the treatment of newborns and infants.

Another analogue based on simethicone is the popular drug "Bobotik". According to the main characteristics, these medicines are similar, but they also have one difference: "Bobotik" can be given no more than 4 times a day, and "Sub Simplex" is suitable for long-term use, and it can be given at each feeding to prevent colic.

According to the principle of influence, one more can be distinguished famous drug, which is often prescribed for infantile colic, is "Baby Calm". This tool is based on vegetable oils and fennel seed extract, which has a complex effect.

It not only provides a mild analgesic and anti-inflammatory effect, but also has sedative effect due to the main active ingredient.

If necessary, "Sub Simplex" and "Baby Calm" can be used simultaneously.

"Sub Simplex" - affordable and effective remedy to fight intestinal colic in children, which begins to act almost immediately after administration and is suitable for use from the first days of life. If the instructions are followed, the drug does not cause side effects and can be used for long-term therapy. In order not to harm your baby, you need to consult your doctor, as there may be individual contraindications.

*registered by the Ministry of Health of the Russian Federation (according to grls.rosminzdrav.ru)

Registration number:

Trade name of the drug:

International non-proprietary name:

Dosage form:

Compound:

100 ml of the drug contains:
Active substance: simethicone 6.919 g (dimethicone 350: silicon dioxide, ratio 92.5% : 7.5%)
Excipients: hypromellose 1.5 g, carbomer 0.6 g, sodium citrate dihydrate 1.0 g, citric acid monohydrate 0.5468 g, vanilla flavor 0.315 g, raspberry flavor 0.108 g, sodium cyclamate 0.2 g, sodium saccharinate 0.02 g, sodium benzoate 0.1 g, polyglycostearyl ester acid 1.0378 g, sorbic acid 0.0347 g, water 89.6189 g.

Description: White to grey-white, slightly viscous suspension with a characteristic fruity odor (vanilla-raspberry).

Pharmacotherapeutic group:

ATX code: A03AX

Pharmacological properties

By reducing the surface tension at the interface, it hinders the formation and contributes to the destruction of gas bubbles in the intestinal contents. The gases released during this can be absorbed by the intestinal walls or excreted due to peristalsis. Prevents interference and overlapping of images during sonography and radiography; promotes better irrigation of the mucous membrane of the large intestine with a contrast agent, preventing the contrast film from breaking.
Simethicone changes the surface tension of gas bubbles formed in the contents of the stomach and intestinal mucus, and causes their destruction. The released gases are absorbed by the intestinal wall or removed during intestinal peristalsis. Simethicone removes foam in a physical way, does not enter into chemical reactions.

Pharmacokinetics

Due to physical and chemical inertness, it is not absorbed in the body; after passing through the gastrointestinal tract, it is excreted unchanged.

Indications for use:

• Used as symptomatic therapy with increased gas formation, flatulence (including in the postoperative period);
• preparation for diagnostic studies gastrointestinal tract (radiography, ultrasound, esophagogastroduodenoscopy);
• acute poisoning with detergents containing surfactants, if they enter the stomach.

Contraindications:

Hypersensitivity to active substance simethicone or any of the auxiliary components of the drug, obstructive diseases of the gastrointestinal tract, intestinal obstruction.

Pregnancy and lactation

Sub ® Simplex can be used during pregnancy and lactation.

Dosage and administration:

Increased gas formation
Newborns and children infancy(up to 1 year of age) receiving feeding from a baby bottle: 15 drops (0.6 ml) of suspension are added to each bottle.
Sub ® Simplex mixes well with other liquids such as milk.
Children from 1 to 6 years old: 15 drops (0.6 ml) during or after meals. If necessary, an additional 15 drops at night.
Children from 6 to 15 years old: 20-30 drops (0.8-1.2 ml).
Adults: 30-45 drops (1.2-1.8 ml).
This dose should be taken every 4 to 6 hours; if necessary, it can be increased.
Sub ® Simplex is best taken with or after meals and, if necessary, at bedtime.
Sub ® Simplex can be given to newborns before feeding with a teaspoon.
Shake the vial vigorously before use. In order for the suspension to start flowing from the pipette, the vial should be turned upside down and tapped on the bottom. Duration of application depends on the dynamics of complaints. Sub ® Simplex, if necessary, can be taken for a long time.

Preparation for diagnostic studies of the gastrointestinal tract
Use in preparation for diagnostic studies of the gastrointestinal tract is facilitated if the pipette is removed from the vial.
X-ray examination: to prepare for radiography the day before the study in the evening, you should take 3-6 teaspoons (15-30 ml) of Sub ® Simplex.
Ultrasound procedure: in preparation for ultrasound, it is recommended to take 3 teaspoons (15 ml) of Sub ® Simplex in the evening the day before the examination and 3 teaspoons 3 hours before the examination.
Endoscopy: before endoscopy, take 1/2 - 1 teaspoon (2.5-5 ml) of Sub ® Simplex. During the study, an additional few milliliters of Sab ® Simplex suspension can be injected through the endoscope.

Detergent poisoning
The dose depends on the severity of the poisoning. The recommended minimum dose of Sub ® Simplex is 1 teaspoon (5 ml).
In cases of persisting existing complaints and / or newly appeared complaints, you should consult a doctor.

Side effect

Allergic reactions are possible.

Overdose

Cases of drug overdose are not known.

Interaction with other drugs

Not installed.

special instructions

The drug Sab ® Simplex can be used, including in patients diabetes, because does not contain carbohydrates.
New and/or recurring complaints related to increased gas formation must be clinically confirmed.

Influence on the ability to drive a car and use machinery

Does not affect the ability to drive a car and operate machinery.

Release form

Suspension for oral administration 69.19 mg / ml. 30 ml bottles of light-protective glass with a drip device (25 drops per 1 ml). Each bottle, along with instructions, is placed in a cardboard box.

Storage conditions:

Best before date:

3 years.
Do not use after the expiry date stated on the package.

Conditions for dispensing from pharmacies:

without recipe

Manufacturing firm:

Pfizer Inc., USA, Produced by: Famar Orleans, France
Address: 235 East 42nd Street, New York, NY 10017 USA,
5, avenue de Concir, 45071 Orléans Sede 2, France

Claims of consumers should be sent to the address of the representative office:

Representative office of Pfizer H. Si. Pi. Corporation (USA),
123317 Moscow, Presnenskaya emb., 10
Naberezhnaya Tower Business Center (Block C)