Almagel neo in sachets instructions for use. Almagel is an effective drug against gastrointestinal disorders. Differences of various forms

Compound

Active ingredients:

5 ml (1 scoop) suspensions contain aluminum hydroxide gel, corresponding to 218 mg of aluminum oxide, magnesium hydroxide paste 350 mg, corresponding to 75 mg of magnesium oxide.

10 ml (1 package) suspensions contain: aluminum hydroxide gel, corresponding to 436 mg of aluminum oxide, magnesium hydroxide paste 700 mg, corresponding to 150 mg of magnesium oxide.

Excipients: hydrogen peroxide solution (30%), sorbitol, hydroxyethyl cellulose, methyl parahydroxybenzoate, propyl parahydroxybenzoate, butyl parahydroxybenzoate, sodium saccharin, propylene glycol, macrogol 4000, lemon oil, ethyl alcohol 96%, purified water.

Description

white or almost white suspension. During storage, a layer of clear liquid may be released on the surface. With vigorous shaking of the contents of the vial, the homogeneity of the suspension is restored.

Pharmacotherapeutic group

PBX code- A02AB10. Antacids, aluminum compounds.

Almagel is a drug that reduces the increased acidity of gastric juice. It is a balanced combination of aluminum and magnesium hydroxides, which are insoluble and hardly enter the body. Almagel has a local effect on the gastric mucosa, protects it from the irritating effect of acids and other harmful substances and food, and reduces the activity of pepsin. The drug reduces the acidity in the esophagus. It has an anti-inflammatory and astringent effect on the mucous membrane of the esophagus, stomach and duodenum. The auxiliary substance sorbitol has a weak carminative and moderate choleretic effect, as well as a moderate laxative effect.

Indications for use

Symptomatic treatment of diseases of the digestive tract, accompanied by increased acidity of gastric juice: esophagitis, hiatal hernia, gastroesophageal reflux disease (GERD), acute and chronic gastritis, gastroluodenitis, peptic ulcer of the stomach and duodenum, post-resection gastritis and gastroanastomositis in the presence of gastroesophageal reflux (heartburn). ). Prophylactically to reduce the irritating and ulcerogenic effect of certain drugs on the mucous membrane of the esophagus, stomach and duodenum (for example, corticosteroids, non-steroidal anti-inflammatory drugs).

Contraindications

The use of Ashiagel is not recommended in case of hypersensitivity to the drug components, habitual constipation, Alzheimer's disease, severe abdominal pain of unspecified origin, suspected acute appendicitis, ulcerative colitis, colostomy or ileostomy, chronic diarrhea, hemorrhoids, severe renal failure , hypophosphatemia, during lactation, children under 10 years of age.

Application Precautions

Keep the following in mind when using this medicine:

In patients with severe constipation; with pain in the stomach of unknown origin and suspected acute appendicitis; in the presence of ulcerative colitis, diverticulosis, colostomy or ileostomy (increased risk of developing disturbances in water and electrolyte balance); chronic diarrhea; exacerbation of hemorrhoids; when changing the acid-base balance in the body and especially in the presence of metabolic alkalosis; with cirrhosis of the liver; with decompensated congestive heart failure; with toxicosis of pregnant women; with renal failure (danger of developing hypermagnesemia and aluminum intoxication).

Patients need to see a doctor in case of weight loss, difficulty in swallowing or constant discomfort in the abdomen, digestive disorders that appeared for the first time; or when changing the course of existing digestive disorders.

Aluminum hydroxide can lead to constipation and magnesium hydroxide can lead to intestinal hypokinesia. The use of this product in high doses may cause or worsen bowel obstruction and ileus, especially in patients at increased risk of such complications, such as patients with renal insufficiency or elderly patients.

The use of antacids containing aluminum in elderly patients should be limited.

With prolonged use of the drug, it is necessary to ensure that a sufficient amount of phosphorus enters the body, since aluminum hydroxide binds to phosphates and reduces their absorption from the digestive tract. The excretion of calcium in the urine increases, which can lead to disturbances in the calcium-phosphate balance and create conditions for the development of osteomalacia (symptoms are complaints of weakness and pain in the bones).

Aluminum hydroxide can be hazardous when used by porphyria patients on hemodialysis.

Since aluminum is concentrated in nervous tissue, the use of aluminum-containing antacids in elderly patients and patients with Alzheimer's disease should be strictly limited. When taken by elderly patients, the course of existing diseases of the bones and joints may worsen.

With prolonged use of the drug (more than 14 days), regular medical supervision and determination of the magnesium content in the blood is necessary in the treatment of patients with renal insufficiency.

Interaction with other medicinal products and other forms of interaction

Please tell your doctor or pharmacist if you are taking or have recently taken other medicines, even if they were not prescribed for you.

With simultaneous treatment, other drugs should be taken 1-2 hours before or after taking Almagel.

Almagel reduces the acidity of gastric juice, and this can affect the action of a large number of drugs while taking.

Almagel reduces the absorption of digoxin‚ indomethacin, salicylates, chlorpromazine, phenytoin, reserpine, H2-blockers (cimetidine, ranitidine, famotidine), lansoprazole, β-adrenergic blockers (for example, atenolol, metoprolol, propranolol, chloroquine, cycline, diflunisal, diphosphonates ( ciprofloxacin, norfloxacin, ofloxacin, enoxacin, grepafloxacin), azithromycin, cefpodoxime, pivampicillin, rifampicin, indirect anticoagulants, barbiturates, fexofenadine, sodium fluoride, dipyridamole, zalcitabine, bile acids (chenodeoxycholic acid and ursodeoxycholic acid), penicillamine glycosides, lankyprolamine, iron, lithium preparations, quinidine, mexiletine, phenothiazine preparations, tetracycline antibiotics, lincosamides, phosphorus preparations, anti-tuberculosis preparations (ethambutol, isoniazid (for oral use), chloroquine, gshococorticoid preparations (known to interact with prednisolone and dexamethasone), kayexelate and ketok onazol.

With the simultaneous administration of enteric drugs, the increased alkalinity of gastric juice can lead to accelerated destruction of their membrane and cause irritation of the stomach and duodenum.

Almagel can affect the results of some laboratory and functional studies and tests: it reduces the level of gastric secretion and, thus, changes the results of a functional study of its acidity; alters technetium (Tc99) test results, such as bone scans and some esophageal tests, increases serum phosphorus, serum and urine pH values.

Taking the drug and eating and drinking

Use during pregnancy and lactation

Before taking any medicines, consult your doctor or pharmacist.

There are no clinical data on the use of Almagel by pregnant women. The drug is not recommended during pregnancy, but if the drug is necessary, then the duration of treatment should not exceed 5-6 days, and the drug should be taken under medical supervision. It is not recommended to prescribe for toxicosis of pregnant women.

There is no data on the intake of the active substances of the drug in difficult milk. Almagel can be used during breastfeeding only after a thorough assessment of the ratio of benefits to the mother and the potential risk to the newborn.

Influence on the ability to drive vehicles and work with machinery

Almagel does not affect the ability to drive a car AND work with machinery. The ethanol included in the preparation is contained in quantities that are not able to affect the ability to drive a car and use machinery when taking the recommended daily doses.

Information about excipients

The drug contains sorbitol, which allows it to be taken by patients with diabetes, but is not suitable for the treatment of patients with congenital fructose intolerance, as it can cause stomach irritation and diarrhea.

The suspension contains parahydroxybenzoates, which can cause an allergic reaction (possibly of a delayed type) and very rarely - bronchospasm.

The drug contains 2.5 vol.% ethyl alcohol (ethanol), which corresponds to the content of 98.1 mg of ethanol in 5 ml and 196.2 mg of ethanol in 10 ml of the drug. Due to the presence of ethyl alcohol in the composition of Almagel, this drug should be used with caution by pregnant, lactating, children and patients with liver disease, epilepsy and alcohol dependence.

Information for correct use

Dosage and administration

Always take Almagel exactly as directed in this leaflet. If you are not sure about something, ask your doctor or pharmacist.

Symptomatic antacid treatment

Adults and children over 14 years of age

5-10 ml (1-2 measuring spoons or 1 packet) 3-4 times a day. If necessary, a single dose can be increased to 15 ml (3 measuring spoons). After achieving a therapeutic effect, the daily dose is reduced to 5 ml (1 measuring spoon) 3-4 times a day or 1-2 packets per day for 2-3 months.

Patients with renal insufficiency

During the treatment of patients with impaired renal function, it is necessary to reduce the daily dose or increase the interval between doses, depending on the severity of renal failure.

Children from 10 to 14 years old

Apply at a dose equal to half the adult dose - 1 scoop 2-4 times a day or 2 scoops 1-2 times a day or 1 packet 1-2 times a day.

For prevention

5-15 ml (1-3 scoops or 1 packet) 15 minutes before taking irritant medications.

Before each dose, the suspension must be thoroughly homogenized by shaking the package!

The drug is taken 45-60 minutes after a meal and in the evening before bedtime.

If you have the impression that Almagel is too weak or too strong, consult your doctor or pharmacist.

If you missed another dose of Almagel, take it when it's time for your next regular dose, so don't increase your dose.

If you have any further questions on the use of this medicine, please ask your doctor or pharmacist.

Overdose

If you have taken a higher dose than you have been prescribed, contact your doctor immediately!

With a single overdose, no other signs of an overdose are observed, except for constipation, flatulence, and a sensation of a metallic taste.

With prolonged use of high doses, the formation of kidney stones, the appearance of severe constipation, slight drowsiness, hypermagnesemia are possible. There may also be signs of metabolic alkalosis: changes in mood or mental activity, numbness or muscle pain, nervousness and fatigue, slow breathing, unpleasant taste sensations.

In these cases, it is necessary to immediately take measures to quickly remove the drug from the body - gastric lavage, stimulation of vomiting, activated charcoal.

If symptoms of an overdose appear, consult a doctor immediately!

Adverse reactions

Like all medicines, Almagel can cause side effects, although not everybody gets them.

From the gastrointestinal tract:

possible appearance of constipation, which disappear with a decrease in dose, diarrhea, discoloration of feces; nausea, vomiting, stomach cramps.

Laboratory indicators:

most often in patients with renal insufficiency and in the case of prolonged use or high doses of the drug due to hypermagnesemia, hyperapuminaemia, aluminum and magnesium intoxication develops; hypophosphatemia (manifestations of which may be loss of appetite, muscle weakness, weight loss); possible hypocalcemia, hypercalciuria.

From the side of the kidneys and urinary tract:

nephrocalcinosis, impaired renal function;

From the immune system:

allergic reactions of local and general type, including itching, urticaria, angioedema and anaphylactic reactions, bronchospasm.

From the side of the central nervous system:

with prolonged use of the drug in patients with renal insufficiency and patients on dialysis, there may be manifestations of encephalopathy, neurotoxicity (changes in mood and mental activity), dementia, disturbances in Alzheimer's disease;

From the musculoskeletal system:

osteoporosis with prolonged use of high doses of a drug with a deficiency of phosphorus in food, osteomalacia may occur;

Others:

change in taste sensations.

With prolonged use of the drug in patients with renal insufficiency and patients on dialysis, manifestations of thirst, lowering blood pressure, hyporeflexia, and the development of microcytic anemia are possible.

Without recipe.

Package

Suspension of 170 ml in bottles of polyethylene terephthalate. One bottle in a carton box with a 5 ml measuring spoon and a leaflet.

10 ml in a bag of multilayer foil. 10 or 20 bags in a carton, including leaflet.

Manufacturer

Balkanpharma - Troyan AD, Bulgaria

5600 Troyan, st. "Krayrichna" No. 1

Tel: (+ 359) 0670 68 104

active substances: 5 ml (1 scoop) suspension contains:

aluminum hydroxide gel in terms of aluminum hydroxide 340 mg,

magnesium hydroxide paste in terms of magnesium hydroxide 395 mg,

emulsions to simethicone 30% in terms of polydimethylsiloxane 36 mg;

10 ml (1 sachet) suspension contains:

aluminum hydroxide gel in terms of aluminum hydroxide 680 mg,

magnesium hydroxide paste in terms of magnesium hydroxide 790 mg,

emulsions to simethicone 30% in terms of polydimethylsiloxane 72 mg;

Excipients: hydrogen peroxide solution (30%), sorbitol (E 420), sodium saccharin, hydroxyethylcellulose, citric acid monohydrate, ethyl parahydroxybenzoate (E 214), propyl parahydroxybenzoate (E 216), propylene glycol, macrogol 400, orange flavor, ethanol 96%, purified water .

Dosage form

Suspension for oral administration.

Suspension of white or almost white color with an orange smell.

Name and location of the manufacturer

Balkanpharma-Troyan AD/Balkanpharma-Troyan AD.

Bulgaria, 5600 Troyan, st. Krayrechna, 1/1, Krayrechna Str., 5600 Troyan, Bulgaria.

Pharmacotherapeutic group

Antacids. Combinations of simple salts and carminatives (antiflatulenti). ATC code A02A F02.

Almagel ® Neo is a balanced gel of aluminum hydroxide and magnesium hydroxide in combination with the vitamin component - simethicone. It has a long antacid effect, has a mild laxative effect, successfully eliminates constipation and reduces flatulence in patients with stomach ulcers.

The dual mechanism of its action, combining acid-neutralizing ability and cytoprotective activity, provides protection of the gastric mucosa and its healing in case of damage.

Alkaline active components of the drug are finely dispersed, which increases their active surface, provides closer contact with the surface of the mucous membrane of the stomach and duodenum, slows down the evacuation of the contents of the stomach and lengthens the neutralizing effect.

Cytoprotective activity is associated with the activation of the synthesis of prostaglandins, which stimulate the secretion of mucus and bicarbonates of the gastric mucosa.

Given the ability of the drug to bind bile acids and lysolecithin, as well as to have a gastroprotective effect, Almagel ® Neo can be used to treat duodenogastric reflux.

Simethicone, which is part of the drug, helps to eliminate flatulence.

Simethicone is a stable silicone substance that is not absorbed from the digestive canal, causing the natural release of gases and their absorption by the intestinal walls.

Simethicone exerts its action in the lumen of the small intestine and is excreted unchanged from the body.

The constituents of the drug are not absorbed in the gastrointestinal tract and thus do not lead to clinically significant plasma concentrations when used at the recommended doses and for the recommended duration of treatment.

Aluminum hydroxide neutralizes the increased secretion of hydrochloric acid in the stomach, forming aluminum chloride. Under the influence of the alkaline environment of the intestine, the latter is converted into alkaline aluminum salts, which are poorly absorbed and excreted in the feces. With normal kidney function, the serum level of aluminum remains practically unchanged.

Magnesium hydroxide also neutralizes hydrochloric acid in the stomach and turns into magnesium chloride. In the intestines, it turns into magnesium carbonate, which is poorly absorbed, so the concentration of magnesium ions in the blood practically does not change.

In patients with chronic renal failure, the level of aluminum and magnesium ions may increase to toxic values ​​due to a violation of their excretion.

Indications for use

Symptomatic treatment of diseases of the digestive tract, which are accompanied by increased or normal acidity of gastric juice and increased gas formation.

The drug is used alone or in combination with other drugs for:

• gastritis and duodenitis;
• stomach ulcer and duodenal ulcer;
• erosions of the stomach and duodenum;
• gastroesophageal reflux disease;
• duodenogastric reflux;
• functional dyspepsia;
• flatulence, discomfort as a result of increased gas formation.

Contraindications

Hypersensitivity to any active and / or auxiliary substances that are part of the drug. Severe renal dysfunction, including in patients on hemodialysis, in whom there is a risk of increasing the concentration of aluminum and magnesium ions in the blood serum to toxic levels as a result of a decrease in excretion through the kidneys. Hypophosphatemia, severe osteoporosis, Alzheimer's disease, habitual constipation, chronic diarrhea, intestinal obstruction, suspected appendicitis, bleeding from the digestive tract of unknown origin, severe abdominal pain of unspecified origin, ulcerative colitis, conditions that cause disturbances in water and electrolyte balance.

Appropriate safety precautions for use

Before starting the use of the drug, the presence of a malignant process should be excluded.

Aluminum hydroxide can cause constipation, and magnesium hydroxide can cause intestinal hypokinesia. The use of this product in high doses may cause or exacerbate bowel obstruction and ileus, especially in patients at increased risk of such complications, such as patients with renal insufficiency or elderly patients.

Patients should see a doctor if:

• weight loss;
• difficulty swallowing or constant discomfort in the abdomen;
• digestive disorders that appeared for the first time or a change in the course of existing digestive disorders;
• kidney failure.

In patients with impaired renal function, an increase in plasma levels of aluminum and / or magnesium is possible, so it should be borne in mind that prolonged use of high doses of the drug can lead to the development of dementia and microcytic anemia.

With prolonged use of the drug, it is necessary to ensure that a sufficient amount of phosphorus enters the body, since aluminum hydroxide binds to phosphates and reduces their absorption from the digestive canal. The excretion of calcium in the urine increases, which can lead to disturbances in the calcium-phosphate balance and create conditions for the development of osteomalacia (symptoms are complaints of weakness and pain in the bones).

During the treatment of patients with renal insufficiency, it is necessary to monitor the dynamics of the indicators of the condition of the kidneys, the size of the ulcer, the appearance of diarrhea, the serum level of aluminum and magnesium.

Each dose (10 ml) of the drug contains:

• 0.226 g of ethanol, the presence of which can adversely affect the condition of patients with liver and brain diseases, in persons with alcohol dependence, epilepsy, in pregnant women and in children under 14 years of age;
• 0.95 g sorbitol, which is contraindicated in patients with rare hereditary diseases such as fructose intolerance.

Parabens, which are part of the drug as excipients, can cause allergic reactions, including urticaria, bronchospasm.

Use during pregnancy or lactation

Due to the lack of data from adequate clinical studies, women during pregnancy Almagel ® Neo can only be used as directed by a doctor if the expected benefit to the mother outweighs the possible risk to the fetus / child.

The content of aluminum and magnesium ions that can affect transit in the gastrointestinal tract should be taken into account, namely:

• magnesium hydroxide salts can cause diarrhea;
• aluminum salts can cause constipation and worsen constipation, often

seen during pregnancy

therefore, long-term use and excess doses of this medicinal product should be avoided.

When Almagel ® Neo is used in pregnant women, the drug may be harmful due to the content of ethyl alcohol (0.226 g per dose).

During treatment with the drug should stop breastfeeding.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms

There is no evidence of a negative effect on the ability to drive vehicles or work with complex mechanisms.

Children

Apply to children over the age of 14 years.

The safety and efficacy of the drug in children under 14 years of age have not been established.

Dosage and administration

Adults and children over 14 years of age:

For gastroesophageal reflux disease, the recommended dose is 10-15 ml (2-3 scoops) or 1 sachet 4 times a day, 1 hour after meals and at bedtime. After achieving the desired effect, the recommended dose is 10 ml (2 scoops) or 1 sachet 4 times a day.

For gastritis, duodenitis, erosions of the stomach and duodenum, peptic ulcer of the stomach and duodenum, duodenogastric reflux, functional dyspepsia, flatulence, the recommended dose is 10 ml (2 scoops) or 1 sachet 4 times a day 1 hour after meals and before sleep.

The duration of treatment is determined by the doctor.

The maximum daily dose is 60 ml (12 scoops or 6 sachets), the maximum duration of treatment is 4 weeks.

If the symptoms do not disappear, you should consult a doctor.

The drug must be taken undiluted. It is not recommended to drink liquids within 30 minutes after taking it. Before use, the suspension must be thoroughly homogenized by shaking the vial.

Patients with impaired renal function. The drug should be taken after consulting a doctor. With prolonged use, the state of kidney function should be taken into account.

Overdose

Prolonged use of Almagel ® Neo can cause hypermagnesemia, despite the fact that the drug is almost not absorbed from the alimentary canal. Symptoms of an overdose are manifested by rapid fatigue, reddening of the face, exhaustion, muscle weakness and inappropriate behavior.

There may also be signs of metabolic alkalosis: changes in mood or mental activity, numbness or muscle pain, nervousness and fatigue, slow breathing, unpleasant taste sensations.

If an overdose of the drug is suspected or if clinical signs appear, it is necessary to stop the drug and take measures to quickly remove the drug from the gastrointestinal tract (introduce activated charcoal, do gastric lavage and other procedures to reduce the absorption of aluminum and magnesium ions).

Treatment for magnesium overdose: rehydration, forced diuresis. You can prescribe calcium gluconate intravenously. In case of renal insufficiency, hemodialysis or peritoneal dialysis is necessary.

Side effects

Prolonged use of Almagel ® Neo or taking high doses can cause phosphorus deficiency syndrome (loss of appetite, muscle weakness, weight loss).

It should be borne in mind that even when using the usual doses of the drug in patients whose diet is characterized by a low phosphorus content, it is possible to reduce the phosphorus content in the body, increase the processes of resorption in bone tissue, hypercalciuria, osteomalacia, osteoporosis, since this drug contains aluminum (see. section "Proper precautions for use"). In patients with renal insufficiency, elevated plasma concentrations of both aluminum and magnesium are observed, therefore, long-term use of high doses of aluminum and magnesium salts can lead to the development of encephalopathy, dementia, microcytic anemia, or worsen the course of dialysis-induced osteomalacia.

Aluminum hydroxide can be dangerous for patients with porphyria who are receiving hemodialysis.

Adverse reactions:

• ;from the gastrointestinal tract: taste disturbance (taste of chalk), diarrhea, constipation, nausea, vomiting, discoloration of feces;
• ;from the immune system: hypersensitivity reactions, including bronchospasm, pruritus, urticaria, angioedema and anaphylactic reactions.

In case of any undesirable effects or unusual reactions, consult your doctor regarding the further use of the drug!

Interaction with other medicinal products and other forms of interaction

Almagel ® Neo interacts with some other drugs that are taken orally. There is a decrease in the volume of absorption of drugs that are taken simultaneously from the gastrointestinal tract. As a measure, a break should be taken between taking antacids and other drugs.

Recommended to be taken 2 hours before or 2 hours after use of the drug Almagel ® Neo: antibiotics of the tetracycline group (tetracycline, doxycycline), fluoroquinolones (ciprofloxacin, norfloxacin, ofloxacin), H 2 -antihistamines, anti-tuberculosis drugs: ethambutol, isoniazid (oral), atenolol, metoprolol, propranolol, chloroquine, cyclini, diflunisal, digoxin, diphosphonates, fexofenadine, iron (salts), sodium fluoride, glucocorticoid drugs (described interaction with prednisolone and dexamethasone), indomethacin, kayexalate, ketoconazole, lansoprazole, lincosamide, phenothiazine antipsychotics, penicillamine, phosphorus (additives), thyroxine.

Combinations to consider: with simultaneous use with salicylates, the excretion of salicylates by the kidneys increases due to alkalinization of urine.

The drug should not be used simultaneously with quinolines.

Elimination of quinidine may be impaired with manifestations of quinidine toxicity, especially in patients with renal insufficiency.

Simultaneous use with cholinergic agents reduces their effectiveness.

The simultaneous use of aluminum hydroxide and citrates can lead to an increase in the level of aluminum, especially in patients with renal insufficiency.

The use of the drug together with drugs that have an enteric membrane may lead to more rapid dissolution of the membrane and irritation of the stomach and duodenum.

The drug may reduce the absorption of folic acid.

When combined with levothyroxine, it is possible to reduce its hormonal action. Pirenzepine enhances and prolongs the action of Almagel ® Neo.

Best before date

Storage conditions

In original packaging at a temperature not exceeding 25 °C. Keep out of the reach of children. Do not freeze!

After the first opening of the primary packaging, the suspension can be stored for 30 days under the indicated conditions.

Package

170 ml or 200 ml in a vial with a measuring spoon.

10 ml in foil sachets. 10 or 20 sachets in a carton box along with instructions for use.

With malnutrition, nervous strain, alcohol abuse or spicy food, decreased immunity and under the influence of pathogenic microorganisms, inflammatory and ulcerative diseases occur in the stomach.

Which are accompanied by pain, discomfort, heartburn, bloating and indigestion.

As part of therapy, the patient is shown drugs that reduce the destructive effect of acid on the walls of the stomach. One of the popular medicines - Almagel A. In addition to neutralizing the acid, it relieves pain and creates a protective layer on the gastric mucosa.

1. Instructions for the drug

Almagel A is a drug of complex action. Envelops the walls of the stomach, has a protective and analgesic effect, reduces acidity.

The effect is noticeable after a few minutes after taking. The active substances are practically not absorbed in the gastrointestinal tract. The effect of the drug lasts up to 60 minutes.

The composition of the drug and the form of release

Under the name Almagel A, a drug is produced in the form of a white suspension. During storage, the suspension can delaminate, with vigorous shaking, uniformity is restored.

Country of origin: Bulgaria. Available in 170 ml plastic bottles and 10 ml bags.

The composition of the drug is presented in the table.

Application of the drug

Apply Almagel A under the following conditions:

Dosage and method of application

Shake the suspension well before taking. If the product is in a bag, knead with your fingers. Do not dilute with water or drink. Take the suspension 10-15 minutes before meals.

Single dose 5–10 ml. The drug can be taken up to 4 times a day. The last dose is before bed. The duration of treatment should not exceed 7 days.

drug interaction

Benzocaine inhibits the antibacterial action of sulfonamides.

The components of Almagel A react and impair absorption:

• tetracyclines,
• ketoconazole,
• glucocorticoids,
• indomethacin,
• acetylsalicylic acid,
• cardiac glycosides,
• cimetidine,
• ethambutol,
• phenothiazine.

The interval between taking different medications is at least 2 hours.

2. Side effects

Possible complications:

Contraindications and application features

Almagel A is contraindicated:

• Children and teenagers. Because of the risk of methemoglobinemia.
• Pregnant and lactating.
• With individual intolerance to any of the components of the remedy.
• With intolerance to anesthetics.
• In cases of chronic stool disorder (prolonged constipation or diarrhea).
• Patients with Alzheimer's disease.
• With pain in the abdomen of unknown origin, including suspected appendicitis.
• In severe cases of renal failure. High risk of intoxication.
• With hypophosphatemia, a drop in the level of phosphates in the body below normal.
• With fructose intolerance (due to sorbitol in the composition of the product).

Almagel A is used with caution in patients with cirrhosis, heart failure, ulcerative colitis, acute hemorrhoids, diverticulosis.

Alcohol and acidic drinks reduce the analgesic effect of benzocaine.

During pregnancy and lactation

Overdose

In the case of a single dose of a large dose of Almagel A, constipation, bloating occur, a taste of metal appears in the mouth. Symptoms resolve on their own and no treatment is required.

With prolonged use of the drug in large doses, poisoning with the components of the drug occurs. Possible complications:

You can neutralize excess magnesium by taking calcium gluconate. If the patient's condition is serious, medical attention should be sought.

3. Shelf life and storage conditions

Store the suspension at room temperature, protected from light. When frozen, it loses its medicinal properties.

The shelf life of the drug is 2 years from the date of manufacture. After the first opening of the bottle - 3 months.

4. Price

Average price in Russia for 10 sachets of 10 ml from 180 rubles; for a bottle of suspension 170 ml - 200 rubles.

A drug Almagel Neo- a combined agent, the action of which is due to its constituent components. It has an antacid, adsorbing, enveloping, carminative effect.
Algeldrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, lower the acidity of gastric juice, and bind bile acids.
The laxative effect of magnesium hydroxide balances the ability of algeldrate to slow down intestinal motility.
Simethicone hinders the formation of gas bubbles and contributes to their destruction. The gases released during this are absorbed by the intestinal walls and excreted from the body due to peristalsis.
Pharmacokinetics
Simethicone, due to physiological and chemical inertness, is not absorbed into organs and tissues and, after passing through the gastrointestinal tract (GIT), is excreted unchanged. Absorption of aluminum and magnesium ions in the intestine is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the level of aluminum and magnesium in the blood may increase to toxic values ​​as a result of a violation of their excretion.

Indications for use

Mode of application

Side effects

Contraindications

Pregnancy

Interaction with other drugs

Overdose

Storage conditions

Release form

Compound

10 ml (1 sachet) suspension Almagel Neo contain: active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 680 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 790 mg;
Simethicone (simeticone emulsion - in terms of dimethicone) 72 mg;
The content of excipients in 10 ml of suspension: hydrogen peroxide solution 30% 0.990 mg, sorbitol 949.20 mg, sodium saccharinate 2.26 mg, hyetellose 11.30 mg, citric acid monohydrate 1130 mg, ethyl parahydroxybenzoate 15.80 mg, propyl parahydroxybenzoate 6, 80 mg, propylene glycol 226.00 mg, macrogol 4000 904.00 mg, orange flavor 4.52 mg, ethanol 96% 226.00 mg, purified water up to 10 ml.

Additionally

main parameters

It has long been known as an indispensable drug for various ulcerative and inflammatory diseases of the digestive tract. Most often, Almagel is taken in the form of a suspension (ready-made or powder for dilution), since it is most effective in the liquid state, tablets are prescribed in exceptional cases.

Heartburn - indications for the appointment of Almagel in sachets

Almagel in sachets is available in 3 forms: Almagel (green packaging), (yellow packaging), Almagel Neo (red packaging). All of these varieties have in their composition two main active ingredients, which provide the protective effect of the drug. These are aluminum hydroxide and magnesium hydroxide. The combination of these components provides the following actions of the drug:

1. Adsorbent. Almagel absorbs harmful substances that irritate the gastric mucosa. It binds and removes toxins from the body.
2. Protective. The drug envelops the walls of the stomach, creating a thin film. This film protects the inflamed walls from the effects of gastric juice, allowing the mucosa to recover and relieve pain.
3. Neutralizing. The drug lowers the acidity of gastric juice. With an ulcer and other inflammations of the gastrointestinal tract, an aggressive effect causes a sharp pain.
4. Mild laxative. Almagel is not a laxative, but a combination of certain components helps prevent constipation. It has been proven that patients who completed the Almagel course had no problems with stool regularity.

In addition to these components, Almagel A includes benzocaine, which is a powerful anesthetic. It is recommended for people with during an exacerbation of the disease. Almagel Neo helps to cope with increased gas formation. It contains a substance called simethicone, which keeps gas from building up and prevents bloating. Indications for the use of Almagel are the following diseases:

1. and duodenum. An ulcer is always accompanied by severe abdominal pain, heartburn, nausea and constipation. All these symptoms are relieved by Almagel A.
2. Gastritis, even in chronic form, periodically reminds of itself with pain in the abdomen. Almagel allows you to relieve pain after eating.
3. This is inflammation of the duodenum, which is also accompanied by pain of varying intensity, nausea, and discomfort after eating.
4. Enteritis is an inflammation of the mucous membrane of the small intestine. Almagel is prescribed as part of therapy to relieve symptoms and prevent constipation.

Rules for taking the drug

Almagel should be taken before meals

Almagel is taken before meals, 30 minutes in advance, for best results, and also at bedtime. The powder must be diluted in water, mix thoroughly. Take 1-3 teaspoons at a time. During the period of exacerbation, you can take Almagel between meals, but not more than 4 tablespoons at a time.

It should be remembered that the protective shell that forms on the walls of the stomach can reduce the absorption of other drugs, so at least 2 hours should elapse between taking Almagel and another medication.

After the main course of treatment has already been completed, the dosage can be reduced and Almagel can be taken for prevention. The daily dose of an adult should be limited to 16 tablespoons. If, according to the doctor's indications, the dosage has to be exceeded, the course of treatment should be short, no more than 2 weeks.

You can change the type of drug. For example, if the disease is accompanied by pain, it is recommended to start treatment with Almagel A. When the condition becomes more stable, the pain subsides, you can switch to regular Almagel.

Almagel reduces the effect of antihistamines, some antibiotics. The drug removes phosphorus from the body and disrupts the absorption of phosphates, so doctors recommend taking additional phosphorus preparations for long-term treatment.

Almagel Neo is taken not before, but after a meal, about an hour later. After taking the drug, you must refuse to take liquids for at least half an hour.

An overdose of Almagel is unlikely, except for Almagel Neo. With prolonged use, redness of the skin, muscle pain, numbness, behavioral disorders, nervousness, and an unpleasant taste in the mouth are observed. All these conditions are caused by a violation of the proper metabolism of trace elements, namely phosphorus, calcium and magnesium. If these signs or any other discomfort appear, stop taking the drug and seek medical help. In severe cases, it is necessary to wash the stomach and take

The drug can be taken not in courses, but one-time in case of discomfort and after a violation of the diet, drinking alcohol or smoking. In case of renal insufficiency, prolonged use of Almagel can cause swelling of the extremities. With fluid retention, you should take a diuretic, and also seek the advice of a doctor. In some cases, the drug must be replaced by an analogue.

Almagel for children and pregnant women

Almagel is prescribed to children both for ulcers and gastritis (in older children), and as an adsorbent and drug (in infants). The previous dosage is for children over 10 years of age. Younger children need to reduce the dosage by half. Almagel Neo is contraindicated for children under 10 years old, while regular Almagel and Almagel A are allowed even for infants from a month old. The dosage should be reduced three times. More often, children are given a ready-made suspension without diluting it.

Almagel: release form - in sachets

Admission rules are the same as for adults. The child should be given 1 teaspoon of the drug half an hour before meals before each feeding (3-4 times a day) and at bedtime. Teenagers and children over 10 years old take 1-2 tablespoons. The total amount of the drug per day for young children should not exceed 5 tablespoons.

The course of treatment lasts approximately 2-3 months. After that, you can continue to give the child a drug for prevention for some time, but by reducing the dosage by half. With prolonged use, you need to additionally give the child phosphorus preparations.

With severe vomiting and abdominal pain, it is recommended to start taking Almagel A, and then switch to regular Almagel. If the treatment includes other drugs, the time difference between doses should be 1.5-2 hours, otherwise their effect will be reduced. as you know, they can also suffer from gastritis, heartburn, ulcers, duodenitis, etc. Regular Almagel and Almagel A are allowed to be used during pregnancy, but not more than 3 days in a row. Almagel Neo is usually not recommended for expectant mothers, since it is not known for certain how it affects the fetus. Sometimes it is still prescribed, in rare cases and under the supervision of a doctor.

The most common reason for taking the drug during pregnancy is severe heartburn, which occurs due to the pressure of the growing uterus on the stomach.

The volume of the stomach decreases, and part of the hydrochloric acid is released into the esophagus, causing discomfort. During pregnancy, it may not appear much, or it may interfere with sleep and lead a normal lifestyle. In the second case, a short course of Almagel is prescribed.

The dosage of the drug is prescribed by the doctor individually in each case. It is usually recommended to drink Almagel 1-2 tablespoons half an hour before meals. If you need to take the drug during lactation, the child at this time should be transferred to the mixture.

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