Calcium with vitamin D3 - official instructions for use. Calcium D3 Nycomed

Trade name of the drug:

CALCIUM WITH VITAMIN D 3

Dosage form:

film-coated tablets

Compound:

Active ingredients
Calcium carbonate is equivalent to 500 mg of calcium.
Vitamin D 3 200 IU.

Excipients - corn starch, polyvinylpyrrolidone, magnesium stearate, hydroxypropylene cellulose, titanium dioxide, purified talc, polyethylene glycol, brown iron oxide, carnauba wax.

Description:

Opaque pink capsule-shaped tablets, film-coated. At the break, a white homogeneous mass surrounded by a thin pink shell.

Pharmacotherapeutic group:

A tool that influences metabolic processes(regulator of calcium and phosphorus metabolism).

PBX code [ A12AX ]

Pharmachologic effect:

Combined drug that regulates the exchange of calcium and phosphorus in the body. Reduces resorption (resorption) and increases bone density, making up for the lack of calcium. Vitamin D 3 is essential for the mineralization of teeth.

Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system.

Pharmacokinetic properties:

Vitamin D 3 is absorbed in the small intestine. Calcium is absorbed in ionized form in the proximal small intestine through an active, D-vitamin dependent transport mechanism.

Indications for use:

Therapeutic and prophylactic agent for conditions of calcium and vitamin D 3 deficiency in the body associated with malnutrition or with an increased need for calcium and vitamin D 3, including:

• The period of pregnancy and breastfeeding.
• Prevention and treatment of postmenopausal and senile osteoporosis, osteomalacia (as part of combination therapy).

Contraindications:

• Hypersensitivity to the components of the drug.
• Pronounced impaired renal function.
• Hypercalcemia ( increased concentration calcium in the blood - in persons with increased function of the parathyroid glands)
• Hypercalciuria (increased concentration of calcium in the urine).
• Urolithiasis (formation of calcium stones).
• Decalcifying tumors (myeloma, bone metastases, sarcoidosis).
• Osteoporosis due to immobilization.
• Tuberculosis of the lungs (active form).
• Childhood.

Dosage and administration:

Before use, consult your doctor.

inside. As a prophylactic adults are prescribed 1-2 tablets per day. To increase calcium absorption, it is preferable to take the tablet with an acidic drink (orange or lemon juice).

For course prevention of osteoporosis 2 tablets per day, one in the morning and one in the evening, preferably with meals.

For the treatment of osteoporosis course and dosage in accordance with the doctor's recommendations.

Side effects:

Possible allergic reactions to the components of the drug. There may be dysfunction gastrointestinal tract(constipation, diarrhea, flatulence, nausea, abdominal pain).

When long-term use an increase in calcium in the blood and urine is possible.

special instructions

• Use with caution in persons suffering from renal insufficiency;
• During the period of treatment, it is necessary to constantly monitor the excretion of calcium in the urine and the concentration of calcium and creatinine in plasma (in case of occurrence of calciuria exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or stop taking it);
• In order to avoid overdose, it is necessary to take into account the additional intake of vitamin D3 from other sources. Do not use simultaneously with vitamin complexes containing calcium and vitamin D 3 ;
• In the elderly, the need for calcium is 1.5 g / day, for vitamin D 3 500-1000 IU / day.

Overdose:

Symptoms of acute and chronic overdose are hypercalcemia and / or hypercalciuria, which are expressed in anorexia, nausea, vomiting, dizziness, weakness, headache. In these cases, it is recommended to stop taking the drug. You should introduce a large amount of fluid into the body and follow a diet with limited number calcium. If symptoms of an overdose appear, you should consult a doctor. An overdose during pregnancy can lead to a violation of the mental and physical development of the child. Ca 2+ and vitamin D 3 pass into breast milk.

Use during pregnancy and breastfeeding.

The need for calcium and vitamin D during pregnancy and lactation increases. When taking the drug, it is necessary to take into account the additional intake of calcium and vitamin D 3 from other sources and carry out constant medical monitoring.

To avoid toxic effects on the fetus, it is not recommended to take more than 1500 mg of calcium and 600 IU of vitamin D per day. Calcium and vitamin D pass into breast milk.

Interaction with other drugs

• The activity of vitamin D 3 may decrease when it is used simultaneously with phenytoin or barbiturates;
• At simultaneous treatment cardiac glycosides, ECG and clinical condition monitoring is necessary, tk. calcium preparations enhance the action of cardiac glycosides;
• The drug slows down the absorption of antibiotics from the tetracycline group, acetylsalicylic acid and other salicylates, sulfonamides, beta-blockers and indirect anticoagulants from the gastrointestinal tract. In this regard, the drug is recommended to be used 2 hours or 2 hours after taking other medicines.
• Cholestyramine, laxatives based on mineral or vegetable oil can reduce the absorption of vitamin D 3 .
• With the simultaneous use of diuretics from the thiazide group, the risk of hypercalcemia increases.

Release form:

20, 50 and 1000 tablets in PVD vials, 1 vial with instructions for use

application in a cardboard box.

Best before date:

2 years.
Do not use after the expiry date stated on the package.

Storage conditions:

Store at temperatures between 15ºC and 30ºC.
Keep out of the reach of children.

Conditions for dispensing from pharmacies:

Without a doctor's prescription.

Manufacturer:

Daru Pakhsh Pharmaceutical MFG. Company, Tehran-Iran

Calcium with Vitamin D3 - medicinal product, its action is aimed at replenishment. The drug is prescribed for therapeutic purposes.

What is the composition and form of release of calcium with vitamin D3?

The pharmaceutical industry produces the drug in capsule-shaped tablets, they are covered with a matte pink film, at the break you can see a white homogeneous mass, which is surrounded by a pink shell. The active components of the drug: colcalciferol, and calcium carbonate is also present.

Excipients of the drug: corn starch, carnauba wax, polyvinylpyrrolidone, hydroxypropyl methylcellulose, titanium dioxide is present, in addition, purified talc, magnesium stearate, polyethylene glycol, and brown iron oxide.

The drug Calcium with vitamin D3 is supplied to the pharmaceutical market in plastic bottles, where there may be different amount tablets, in particular 20, 50 or 1000. The drug is packed in cardboard boxes, on which there is a date for the manufacture of the drug, as well as the sale of the drug, in this case it is two years. Sold in the OTC department.

What is the effect of calcium with vitamin D3?

The drug Calcium with vitamin D3 affects metabolic processes phosphorus and calcium, regulating them. Reduces resorption (resorption) of bones, and also increases their density, making up for the lack mineral components. Colecalciferol is also involved in the mineralization of teeth.

In addition, calcium is involved in nerve conduction, regulates muscle contractions, and is also considered one of the components of the blood coagulation system. The drug is absorbed mainly in the small intestine, that is, in its proximal section.

What are the indications for calcium with vitamin D3?

The drug is prescribed as a therapeutic and prophylactic agent in a state of deficiency of calcium and vitamin D3, associated with an increased need for these compounds or arising against the background of an inferior and during pregnancy.

The drug is effective in postmenopausal osteoporosis, as well as in senile osteoporosis, tablets are prescribed for osteomalacia.

What are the contraindications for calcium with vitamin D3?

I will list the conditions when calcium with vitamin D3 instructions for use prohibit the use of:

In order to prevent osteoporosis, the patient should take two tablets, it is best to use the medicine during meals. To treat this process daily dosage the doctor selects the medication, as well as the duration of the therapeutic course.

This drug may slightly slow absorption in digestive tract antibiotics of the tetracycline group, in addition, as well as other salicylates, indirect anticoagulants and beta-blockers. In this regard, calcium with vitamin D3 is recommended to be taken two hours before or after the use of other drugs.

Overdose of calcium with vitamin D3

During an overdose of these tablets, the patient will develop the following symptoms: weakness is characteristic, hypercalcemia or hypercalciuria is laboratory determined, which will be accompanied by nausea or vomiting.

In this situation, stop using medication and urgently proceed to gastric lavage, in addition, the patient is symptomatic treatment, after which a diet with a reduced calcium content in foods is prescribed.

What are the side effects of calcium with vitamin D3?

The use of the drug can provoke the development side effects, while the patient may have constipation or bloating occurs, in addition, sometimes there is a feeling of nausea, as well as pain in the epigastrium.

Other negative manifestations in response to the use of these tablets can be expressed as allergic reactions, with prolonged use medication the patient has changes laboratory indicators in the form of hypercalcemia or hypercalciuria.

If the above symptoms appear, the patient should consult a specialist in a timely manner.

special instructions

During therapy with this drug, constant control for calcium parameters both in urine and in bloodstream, with the development of calciuria, the dose of the drug is reduced or the tablets are stopped.

How to replace calcium with vitamin D3, what analogues?

Analogue drugs include the following medicines: Vitrum Calcium + Vitamin D3, in addition, Vitrum Calcium, Ideos, as well as Calcium-D3 Nycomed.

Conclusion

When taking this drug, you should adhere to the dosages recommended by the doctor.

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Combined drug that regulates the exchange of calcium and phosphorus in the body (in bones, teeth, nails, hair, muscles).

Reduces resorption (resorption) and increases bone density, making up for the lack of calcium and vitamin D 3 in the body, necessary for the mineralization of teeth.

Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system. Adequate calcium intake is especially important during growth, pregnancy and lactation.

Vitamin D 3 increases the absorption of calcium in the intestine.

The use of calcium and vitamin D 3 prevents an increase in the production of parathyroid hormone, which is a stimulator of increased bone resorption (washing out of calcium from the bones).

Pharmacokinetics

Suction

Usually the amount of calcium that is absorbed from the gastrointestinal tract is approximately 30% of the dose taken.

Distribution and metabolism

99% of the calcium in the body is concentrated in the hard structure of bones and teeth. The remaining 1% is found in intra- and extracellular fluids. About 50% of the total calcium in the blood is in a physiologically active ionized form, of which approximately 10% is in combination with citrate, phosphate or other anions, the remaining 40% is associated with proteins, primarily with albumin.

breeding

Calcium is excreted through the intestines, kidneys and sweat glands. Renal excretion depends on glomerular filtration and tubular calcium reabsorption.

Colecalciferol

Suction

Colecalciferol is readily absorbed from the small intestine (about 80% of the dose taken).

Distribution and metabolism

Colecalciferol and its metabolites circulate in the blood bound state with specific globulin. Colecalciferol is metabolized in the liver by hydroxylation to 25-hydroxycolecalciferol. Then it is converted in the kidneys to active form 1.25-hydroxycholecalciferol. 1.25-hydroxycholecalciferol is the metabolite responsible for increasing calcium absorption. Unchanged colecalciferol is deposited in adipose and muscle tissue.

breeding

Colecalciferol is excreted by the kidneys and through the intestines.

Release form

Chewable tablets (orange) without shell, round, biconvex, white color; with orange flavor; may have small inclusions and jagged edges.

Excipients: sorbitol - 390 mg, isomalt - 62.0 mg, povidone - 36.4 mg, magnesium stearate - 6.00 mg, aspartame - 1.00 mg, orange oil - 0.97 mg, mono- and diglycerides fatty acids- 0.0008 mg.

20 pcs. - polyethylene bottles high density(1) - packs of cardboard.
50 pcs. - high-density polyethylene bottles (1) - cardboard packs.
100 pieces. - high-density polyethylene bottles (1) - cardboard packs.

Dosage

Tablets can be chewed or sucked and taken with meals.

Calcium-D 3 Nycomed

Adults for the prevention of osteoporosis - 1 tab. 2 times / day; in complex therapy osteoporosis - 1 tab. 2-3 times / day.

To compensate for the deficiency of calcium and vitamin D, adults and children over 12 years old - 1 tab. 2 times / day, children from 5 to 12 years old - 1-2 tablets / day, children from 3 to 5 years old - dosage in accordance with the doctor's recommendations.

Calcium-D 3 Nycomed Forte

Adults for the prevention of osteoporosis - 1 tab. 2 times / day or 2 tablets 1 time / day; in the complex therapy of osteoporosis - 1 tab. 2-3 times / day.

To compensate for the deficiency of calcium and vitamin D, adults and children over 12 years old - 2 tablets per day, children from 3 to 12 years old - 1 tablet per day or as directed by a doctor.

Duration of treatment

When used for prevention and in the complex therapy of osteoporosis, the duration of treatment is determined by the doctor individually.

When used to compensate for the deficiency of calcium and vitamin D 3 average duration course of treatment for at least 4-6 weeks. The number of repeated courses during the year is determined individually.

Patients with impaired liver function dose adjustment is not required.

Should not be used in severe renal failure.

Elderly patients are prescribed the same dose as for adults. Should be considered possible reduction creatinine clearance.

Overdose

Symptoms: manifestations of hypercalcemia - anorexia, thirst, polyuria, muscle weakness, nausea, vomiting, constipation, abdominal pain, fatigue, bone pain, mental disorders, nephrocalcinosis, urolithiasis disease and, in severe cases, cardiac arrhythmias. At long-term use excess doses (over 2500 mg of calcium) - kidney damage, soft tissue calcification.

If symptoms of an overdose are detected, the patient should stop taking calcium and vitamin D, as well as thiazide diuretics and cardiac glycosides, and consult a doctor.

Treatment: gastric lavage, replacement of fluid loss, the use of "loop" diuretics (for example, furosemide), corticosteroids, calcitonin, bisphosphonates. It is necessary to control the content of electrolytes in the blood plasma, kidney function and diuresis. In severe cases, it is necessary to measure the central venous pressure and control the ECG.

Interaction

Hypercalcemia can potentiate the toxic effects of cardiac glycosides when used simultaneously with calcium and vitamin D preparations. ECG and serum calcium monitoring is necessary.

Calcium preparations can reduce the absorption of tetracyclines from the gastrointestinal tract. Therefore, tetracycline drugs should be taken at least 2 hours before or 4-6 hours after taking the drug.

To prevent a decrease in the absorption of bisphosphonate preparations, it is recommended that they be taken at least 1 hour before taking Calcium-D 3 Nycomed.

Corticosteroids reduce calcium absorption, so treatment with corticosteroids may require an increase doses of Calcium-D 3 Nycomed.

With the simultaneous use of thiazide diuretics, the risk of hypercalcemia increases, because. they increase tubular reabsorption of calcium. With the simultaneous use of thiazide diuretics, the calcium content in the blood serum should be regularly monitored.

Calcium reduces the effectiveness of levothyroxine by reducing its absorption. The period of time between taking levothyroxine and Calcium-D 3 Nycomed should be at least 4 hours.

The absorption of antibiotics of the quinolone group is reduced with simultaneous use with calcium preparations. Therefore, antibiotics of the quinolone group should be taken 2 hours before or 6 hours after taking Calcium-D 3 Nycomed.

Reception food products containing oxalates (sorrel, rhubarb, spinach) and fitin (cereals), reduces the absorption of calcium, so you should not take Calcium-D 3 Nycomed within 2 hours after eating sorrel, rhubarb, spinach, cereals.

Side effects

Frequency side effects the drug is regarded as follows: very frequent (> 1/10); frequent (>1/100,<1/10); нечастые (>1/1000, <1/100); редкие (>1/10 000, <1/1000); очень редкие (<1/10 000).

From the side of metabolism and nutrition: infrequent - hypercalcemia, hypercalciuria.

From the digestive system: rarely - constipation, flatulence, nausea, abdominal pain, diarrhea, dyspepsia.

On the part of the skin and subcutaneous tissue: very rarely - itching, rash, urticaria.

Indications

• prevention and treatment of calcium and/or vitamin D 3 deficiency;
• prevention and complex therapy of osteoporosis and its complications (bone fractures).

Contraindications

• hypercalcemia;
• hypercalciuria;
• nephrolithiasis;
• hypervitaminosis D;
• severe renal failure;
• active form of tuberculosis;
• sarcoidosis;
• hypersensitivity to the components of the drug, soy or peanuts.

The drug in the form of tablets is not used in children under the age of 3 years.

The drug contains sorbitol, isomalt and sucrose, so its use is not recommended for patients with hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency.

With caution: pregnancy, lactation, renal failure.

Application features

Use during pregnancy and lactation

Calcium and vitamin D 3 are used during pregnancy to make up for their deficiency in the body.

During pregnancy, the daily dose of the drug should not exceed 1500 mg of calcium and 600 IU of vitamin D 3.

Hypercalcemia due to overdose during pregnancy can have an adverse effect on the developing fetus.

The drug is used during lactation.

Calcium and vitamin D 3 can pass into breast milk, so the intake of calcium and vitamin D from other sources in the mother and child must be taken into account.

Application for violations of kidney function

Use in children

special instructions

With long-term therapy, the content of calcium and creatinine in the blood serum should be monitored. Observation is especially important in elderly patients with simultaneous treatment with cardiac glycosides and diuretics and in patients with an increased tendency to form kidney stones. In cases of hypercalcemia or signs of impaired renal function, reduce the dose or stop treatment.

Vitamin D should be taken with caution in patients with renal insufficiency. In this case, it is necessary to control the content of calcium and phosphates in the blood serum. It is also necessary to take into account the risk of soft tissue calcification.

In order to avoid overdose, it is necessary to take into account the additional intake of vitamin D from other sources.

Calcium and vitamin D 3 should be used with caution in immobilized patients with osteoporosis due to the risk of hypercalcemia.

Simultaneous use with antibiotics of the tetracycline or quinolone group is usually not recommended, or should be carried out with caution.

Influence on the ability to drive vehicles and control mechanisms

The drug does not affect the ability to drive vehicles or work with technically complex mechanisms.

Composition of 1 chewable tablet:

• - 1250 mg (in terms of elemental calcium - 500 mg);
• cholecalciferol - 5.0 µg, which corresponds to 200 international units;
• - 390 mg;
• isomalt - 62.0 mg;
• povidone - 36.4 mg;
• magnesium stearate - 6.00 mg;
• - 1.0 mg;
• orange oil 0.97 mg or mint flavor 31.9 mg;
• mono and diglycerides of fatty acids - 0.0008 mg.

Compound Calcium D3 Nycomed Forte(1 chewable tablet):

• calcium carbonate – 1250 mg (equivalent to 500 mg of elemental calcium);
• vitamin D3 (cholecalciferol) - 10 mcg (400 IU);
• sorbitol - 390 mg;
• isomalt - 49.9 mg;
• povidone - 36.4 mg;
• magnesium stearate - 6 mg;
• aspartame - 1.0 mg;
• lemon oil - 0.78 mg;
• mono and diglycerides of fatty acids - 0.0006 mg.

Release form

• orange or mint chewable tablets Calcium D3 Nycomed white, not having a shell, biconvex, round shape with the appropriate aroma. Small dot inclusions and jagged edges are allowed. Tablets are packaged in high-density polyethylene bottles of 20.50 or 100 pieces. The carton contains 1 vial with the drug and annotation to the drug.
• Calcium Nycomed D3 Forte- round chewable tablets with lemon flavor. Biconvex tablets do not have a shell and are sold in high-density polyethylene bottles of 30, 60 and 120 pieces. 1 vial and instructions for use of the drug are enclosed in a cardboard pack.

pharmachologic effect

The drug refers to combined pharmaceutical preparations that regulate the exchange of calcium and phosphorus in the body and compensate for the deficiency of the main structural element. The biochemical role of calcium lies in the physiological construction of bone tissue, mineralization of teeth, the processes of coagulation and transmission of a nerve impulse, and the implementation of muscle contractions. In response to its increase in the systemic circulation, bone density increases, calcium excretion by the kidneys decreases.

cholecalciferol is responsible for the absorption of the element in the gastrointestinal tract and its distribution in the body. Oral administration of the drug inhibits the synthesis parathyroid hormone - a natural hormone of the parathyroid gland, which largely affects the phosphorus-calcium metabolism. Accordingly, the amount of calcium absorbed from the digestive tube increases and its resorption (washout) from bones and other organs decreases.

Pharmacodynamics and pharmacokinetics

Calcium absorbed from the proximal digestive tube in an amount of 30% of the dose taken, after which the element enters the systemic circulation, where 50% is in an active ionized form, that is, the active substance binds to citrates, phosphates, and some other anions and protein structures. The main building component is eliminated by the intestines, sweat glands and kidneys. When calculating excretion, it should be taken into account that renal excretion of calcium depends not only on glomerular filtration, but also on tubular reabsorption.

Vitamin D3 It is absorbed mainly from the small intestine, from where about 80% of the dose taken enters the main bloodstream, where it binds to a specific transport globulin. The metabolism of cholecalciferol includes two stages - first, the vitamin is converted into 25-hydroxycholecalciferol by hydroxylation, after which, getting into the kidneys, it is transformed into an active form - 1,25-hydroxycholecalciferol . Unchanged vitamin is stored by the body in muscle and adipose tissue. Cholecalciferol is excreted by how much and intestines.

Indications for use

• prevention and complex treatment ;
• deficiency of calcium and / or vitamin D3;
• bone fractures.

Contraindications

Absolute contraindications to the use of a pharmaceutical product:

• hypervitaminosis D;
• hypercalcemia - increased calcium in the blood;
• hereditary fructose intolerance;
• immobilized patients;
• hypercalciuria - the appearance of calcium in the urine;
• glucose-galactose malabsorption;
• nephrolithiasis and other diseases, in the pathogenesis of which the formation of calcium stones is noted;
• active form ;
• sucrose-isomaltase deficiency;
• increased sensitivity to the constituent components of the medicinal product or to food products such as soy and peanuts;
• children's age up to 3 years.

Side effects

• From the side metabolism: hypercalcemia and hypercalciuria.
• From the side gastrointestinal tract: (constipation ), flatulence , , nausea , abdominal pain , .
• From the side skin and subcutaneous tissue: rash , , .

Instructions for Calcium D3 Nycomed (Method and dosage)

Instructions for use of the pharmaceutical product indicate that the drug is used orally, and the tablets should be chewed or sucked during meals. For prevention osteoporosis the dosage of Calcium D3 Nycomed is used: 1 tablet 2 times a day or 2 tablets 1 time a day. With the aim of complex therapy for this pathological condition, 1 tablet of Ca D3 Nycomed is taken 3 times a day. The duration of such treatment is prescribed individually, based on the biochemical parameters of metabolic processes and the state of bone tissue, teeth and skin derivatives (hair and nails).

For liquidation scarce states the duration of the course of treatment is at least 4-6 weeks, and the dosage necessarily takes into account the age category of the patient:

• children from 3 to 5 years - 1 or ½ tablets per day;
• from 5 to 12 years - 1-2 tablets per day;
• adults and adolescents over 12 years old - 1 tablet 2 times a day.

The instruction for Calcium D3 Nycomed Forte differs only in the dosage of the drug and the duration of the course of conservative therapy, therefore, when prescribing it, these aspects of the drug correction of phosphorus-calcium metabolism should be further discussed with the attending physician.

Overdose

In the event of an overdose of a pharmaceutical preparation, symptoms develop that indicate hypercalcemia :

• anorexia ;
• dry mouth, thirst;
• muscle weakness;
• nausea and other dyspeptic disorders;
• polyuria ;
• bone pain;
• mental disorders;
• nephrocalcinosis ;
• (with a prolonged increase in the concentration of calcium in the blood);
• (in especially severe cases);
• soft tissue calcification;
• organic kidney damage.

If symptoms of overdose are detected calcium and vitamin D3 you should immediately stop taking the pharmaceutical product, tiazide diuretics and cardiac glycosides (features of the pharmacokinetics of therapeutic properties are indicated in the "Interactions" section) and consult your doctor. As a rule, "loop" diuretics are prescribed for therapeutic purposes (the drug of choice is ), oral glucocorticosteroids, , bisphosphonates. In case of an overdose, the following physiological parameters should be monitored:

• the content of electrolytes in blood plasma;
• functional ability of the kidneys and diuresis;
• central venous pressure;
• electrical activity of the heart.

Interaction

With the combined use of Calcium D3 Nycomed and cardiac glycosides potentiation of the toxic effect of the latter is possible, therefore, if necessary, their simultaneous use is recommended careful monitoring of electrocardiography and calcium concentration in the blood.

Calcium may decrease absorption capacity groups quinoline and row , as well as , bisphosphonates therefore, these drugs should be taken no earlier than 2 hours before or 6 hours after the use of drugs based on the physiological "builder" of the body's skeletal system.

Glucocorticosteroids , barbiturates ,laxatives , phenytoin and reduce the bioavailability of the oral therapeutic agent, that is, the active ingredients are absorbed in the gastrointestinal tract in smaller quantities, therefore, it is necessary to correct the dosage or dosage regimen of Calcium D3 Nycomed during conservative sanitation, involving the combination of the drug with other pharmaceutical products.

Thiazide diuretics in pharmacy they are sometimes called sparing, since pharmaceuticals of this series inhibit the tubular reabsorption of calcium and some other micro- and macroelements, as a result of which regular monitoring of calcium in the blood serum is required to avoid hypercalcemia and overdose.

Use food products , which contain oxalates (sorrel, potatoes, spinach, rhubarb) or (most crumbly cereals), reduces the ability of calcium to be absorbed in the gastrointestinal tract, therefore, the daily diet should be adjusted in a special way. Do not take a pharmaceutical product within four hours of eating any of the foods listed above.

Terms of sale

The sale of a pharmaceutical product involves over-the-counter dispensing at pharmacy kiosks.

Storage conditions

Store the drug in a tightly closed vial in a dry place out of the reach of children. The temperature regime is not higher than 25 degrees Celsius.

Best before date

special instructions

Brief information about the manufacturer

Nycomed is a Swiss pharmaceutical company founded back in 1874 with headquarters in Zurich, and is widely known for such medicinal products as, and Calcium D3 . Until a certain time, it was one of the 30 largest corporations in the world in terms of sales in the market of conservative therapeutic agents. In September 2011, it was bought by a Japanese company Takeda, one of whose areas of interest is metabolic diseases and their correction with the help of drug treatment. Therefore, the official website of Nycomed is now represented by an Internet resource managed by Takeda.

The impact of a pharmaceutical product on areas of daily life

Calcium D3 Nycomed is a combined drug with a marked selectivity of therapeutic action, that is, the active ingredients of chewable tablets and their auxiliary components do not affect the ability to concentrate, prolonged attention, or other areas of everyday life. During the course of treatment, it is allowed to independently drive vehicles and work with technical complex mechanisms.

Analogues Calcium D3 Nycomed

Coincidence in the ATX code of the 4th level:

The drug belongs to the group of combined drugs for the regulation of calcium levels in the blood and the content of a structural element in body tissues. Of course, there are various analogues of chewable tablets. As a rule, preparations are presented directly by the biogenic component and excipients for a more complete realization of its therapeutic properties. So it should be noted:

• - mainly used for the children's age category to prevent calcium deficiency;
• Ideos - chewable tablets prescribed for senile, age-related osteoporosis or its occurrence due to menopause;
• - used for idiopathic progressive lack of calcium and its complications in the form of bone fractures or dental problems.

These drugs are prescribed if there are any absolute or relative contraindications to Calcium D3 Nycomed, for example, with increased sensitivity to its auxiliary components, in order to avoid or the development of adverse effects of conservative therapy. The price of analogues Calcium D3 Nycomed, as a rule, is higher, which gives a clear advantage to this pharmaceutical agent for the correction of phosphorus-calcium metabolism.

Calcemin or Calcium D3 Nycomed - which is better?

is one of the most popular analogues of Calcium D3 Nycomed. This is a combined pharmaceutical preparation, the composition of which includes calcium carbonate , vitamin D3 , copper and zinc oxide, manganese sulfate and sodium borate. Coated tablets are prescribed not only for violations of phosphorus-calcium metabolism, but also to compensate for the deficiency of certain trace elements , which are of great biological importance for the normal functioning of the body.

dosage of calcium and cholecalciferol in Calcemin is an order of magnitude less than in chewable tablets Calcium D3 Nycomed, which leads to fewer side effects, a sharply reduced chance of overdose. But the composition of the drug also determines more long course of medication therapy with, because it is prescribed mainly for adolescents and women during pregnancy or lactation. Calcium D3 Nycomed, in turn, copes much more effectively with its main task - the regulation of phosphorus-calcium metabolism and the elimination of relevant complications.

Calcium D3 Nycomed for children

In childhood, metabolic progressive diseases are especially difficult to tolerate, because the young organism is still at the stage of development and the stock of compensatory-adaptive mechanisms has not yet been fully formed. Calcium and vitamin D deficiency is one of the most pressing problems described by pediatric orthopedics, because due to this pathological deficiency, a large number of severe nosological units up to delays in mental and physical development Therefore, it is so important to undergo regular medical examinations and correct all diagnosed disorders in a timely manner.

How to take Calcium D3 Nycomed for children should be checked with the attending pediatrician for sure, because its dosage is selected individually, taking into account the current level of blood calcium, concentration parathyroid hormone and some other biochemical indicators.

The standard scheme of conservative therapy provides for the appointment of 1 tablet 1-2 times a day at the age of 5 to 12 years, and for adolescents over the age of 12 years - 1 chewable tablet 1-3 times a day. It should be understood that an excess of a pharmaceutical product, as well as its deficiency, can lead to the adverse effects described in the "Overdose" section.

With alcohol

Alcohol abuse is a common cause scarce states , since alcohol contributes to the leaching of micro- and macroelements, as well as vitamin structures from tissues and organs, therefore bad habits should be completely excluded for the period of a conservative course of treatment with calcium-based chewable tablets. As a preventive measure, it is recommended to significantly limit the proportion of alcoholic beverages, caffeine and smoking in the future.

Calcium D3 Nycomed during pregnancy and lactation

The insufficiency of micro- and macroelements for pregnant women is a common condition, because the woman's body provides not only her needs, but also supplies the necessary structural "bricks" for the normal organization of the tissues and organs of the child. Especially often manifested calcium deficiency - one of the main components of the skeleton, muscle organs and nervous system, however, it is quite difficult to digest, therefore it is recommended to use special preparations that compensate for the state of insufficiency. Medicines are prescribed if the following symptoms of calcium deficiency during pregnancy are observed:

• back pain;
• numbness of the upper and lower extremities;
• hair loss and brittle nails;
• tooth decay;
• leg cramps.

Calcium D3 Nycomed during pregnancy is the drug of choice to compensate for the deficiency of a structural element in the mother's body. First of all, the drug in a relatively short time allows you to eliminate the lack of calcium and restore pathologically altered functions of the body. It should also be noted that the oral form of chewable tablets is more physiological and to a lesser extent can cause any side effects or adverse effects for a woman and her unborn child.

Tablets Calcium D3 Nycomed can also be used for breastfeeding , however, it should be borne in mind that the active constituents of the pharmaceutical preparation have the ability to penetrate into breast milk during lactation, and therefore it is necessary to accurately correlate other sources of calcium and vitamin D in the body of the newborn. When prescribing Calcium D3 Nycomed, young mothers should definitely find out the symptoms hypervitaminosis and hypercalcemia in a small child, in order to stop the use of the drug in time.