All about aspirin. Low risk group - does not need aspirin therapy. Beauty recipes with acetylsalicylic acid

Aspirin is intended for blood thinning, prevention of thrombosis, treatment of myocardial diseases and headaches - the instructions for using the medication contain all the necessary information for the patient. The drug is known for its ability to relieve fever and relieve pain due to the active composition. Read the instructions for its use.

What is Aspirin

According to the pharmacological classification, Aspirin is included in the group of non-steroidal anti-inflammatory drugs (NSAIDs) with antiplatelet properties. This allows it to have a wide spectrum of action - from pain relief to preventive action against cardiovascular diseases. The active ingredient of the composition is acetylsalicylic acid. She is responsible for the effect of the drug.

Composition of aspirin tablets

On sale there are effervescent and classic Aspirin tablets, as well as with the prefix "cardio". All of them contain acetylsalicylic acid as an active ingredient. The composition is indicated in the table:

Action of Aspirin

Acetylsalicylic acid refers to non-steroidal components, has an antipyretic effect, analgesic and anti-inflammatory effect. Once in the body, the substance inhibits the work of cyclooxygenase enzymes (it is an inhibitor) that take part in the production of prostaglandins. It reduces the temperature during influenza, relieves joint and muscle pain, and inhibits platelet aggregation.

Once inside, acetylsalicylic acid is completely absorbed from the gastrointestinal tract. Under the influence of liver enzymes, the substance is converted into salicylic acid (the main metabolite). In women, the metabolism is slower due to the low activity of blood serum enzymes. The substance reaches its maximum concentration in the blood plasma after 20 minutes.

The substance binds to blood proteins up to 98%, crosses the placenta and into breast milk. The half-life is 2-3 hours at low doses and up to 15 at high doses. Compared with the concentration of salicylates, acetylsalicylic acid does not accumulate in the serum, it is excreted by the kidneys. With normal functioning of the urinary tract, up to 100% of a single dose of the substance is excreted in 72 hours.

Indications for use

According to the instructions, the use of Aspirin is indicated for the prevention of heart attack, stroke, thrombosis, varicose veins; patients with the following conditions:

• headache, toothache, menstrual, muscle, joint pain;
• pain in the throat, back;
• increased body temperature with a cold or infectious and inflammatory diseases;
• angina pectoris, coronary artery bypass surgery.

How to take Aspirin

The instructions for use say that the drug is prescribed for adults and children over 15 years of age. It is taken after a meal with a glass of clean water. The duration of treatment without consulting a doctor should not exceed a week as an anesthetic and three days to relieve fever. If you need to take aspirin for a long time, contact your doctor for a lower dose, complex drug treatment, or a diagnosis to detect Helicobacter pylori infection.

Effervescent tablets dissolve in a glass of water, taken orally after meals. A single dose is 1-2 pieces, the maximum daily dose is 6 pieces. The intervals between doses are from 4 hours. The duration of treatment without medical advice is five days for pain relief and three days for fever reduction. An increase in the dosage and duration of the course is possible after visiting the doctor.

Aspirin for the heart

Acetylsalicylic acid prevents the formation of blood clots by preventing blockage of blood vessels by platelet clots. Small doses of Aspirin have a beneficial effect on the state of the blood, which makes it possible to use it to prevent the occurrence of cardiovascular diseases. Indications for use are risks in the presence of diabetes, obesity, arterial hypertension; suspected heart attack, prevention of thromboembolism.

To reduce the amount side effects, you need to use a special enteric form of the drug (Aspirin Cardio), inject solutions with the drug intravenously or intramuscularly, use a transdermal patch. According to the instructions, for the prevention of strokes take a dose of 75-325 mg / day, during a heart attack or a developing ischemic stroke - 162-325 mg (half a tablet - 500 mg). When taking the enteric form, the tablet must be crushed or chewed.

For a headache

With pain syndromes of the head of mild and moderate intensity or a feverish state, you need to take a single dose of 0.5-1 g of the drug. The maximum single dose is 1 gram. The intervals between doses should be at least four hours, and the maximum daily dosage should not exceed 3 g or six tablets. Aspirin should be taken with plenty of liquid.

With varicose veins

Acetylsalicylic acid thins the blood, so it can be used to prevent platelets from sticking together and blockage of veins. The drug inhibits blood clotting, can be used to treat varicose veins and prevent its complications. To do this, use Aspirin Cardio, because it treats the body more carefully and does less harm to the gastric mucosa. According to the instructions, the treatment of veins should be accompanied by the intake of 0.1-0.3 g of the drug per day. The dosage depends on the severity of the disease, the weight of the patient, and is prescribed by the doctor.

special instructions

In the instructions for the use of Aspirin there is a point of special instructions, which contains the rules for using the drug:

• For a quick effect, chew or grind the medication.
• Always take medicine after meals so as not to injure the gastric mucosa.
• The drug can cause bronchospasm, an attack of bronchial asthma, sensitivity reactions (risk factors - fever, nasal polyps, chronic diseases of the gastrointestinal tract, bronchi and lungs).
• The drug increases the tendency to bleeding, which should be taken into account before surgery, tooth extraction - you should stop taking the drug 5-7 days before the operation and warn the doctor.
• The drug reduces the excretion of uric acid from the body, can provoke an attack of acute gout.

During pregnancy and lactation

Aspirin is contraindicated for use in the first and third trimesters of pregnancy due to the ability of acetylsalicylic acid to penetrate the placental barrier. In the second trimester, the use requires caution, only as prescribed by a doctor and if the benefit to the mother exceeds the risk to the fetus. During lactation, Aspirin, according to reviews and instructions, is prohibited, because it passes into breast milk.

Application in childhood

According to the instructions, children under 15 years of age are prohibited from using Aspirin and other drugs with acetylsalicylic acid due to an increased risk of developing Reye's syndrome against the background of viral diseases. This condition is characterized by the appearance of encephalopathy and acute fatty degeneration of the liver with a parallel course of acute liver failure.

drug interaction

The instructions for the use of Aspirin indicate a possible drug interaction of acetylsalicylic acid with other medicines:

• The drug increases the toxic effect of Methotrexate, narcotic analgesics, other NSAIDs, hypoglycemic oral agents.
• The agent increases the activity of sulfonamides, reduces - antihypertensive drugs and diuretics (Furosemide).
• In combination with glucocorticosteroids, alcohol and ethanol-containing drugs, the risk of bleeding and damage to the gastrointestinal mucosa increases.
• The agent increases the concentration of Digoxin, lithium preparations, barbiturates.
• Antacids with magnesium or aluminum hydroxide slow down the absorption of the drug.

Side effects

The instructions for use indicate the following side effects of Aspirin that develop in patients:

• abdominal pain, heartburn, vomiting blood, nausea, tarry stools;
• hidden signs of bleeding: iron deficiency anemia, perforation or erosion of the walls of the stomach and intestines;
• dizziness, tinnitus;
• urticaria, bronchospasm, angioedema, other allergic reactions.

Overdose

According to the instructions, symptoms of a moderate overdose are nausea, vomiting, hearing loss, tinnitus, confusion, dizziness, and headaches. They go away when the dose is reduced. Signs of a severe stage of overdose are fever, respiratory alkalosis. The patient may present with coma, cardiogenic shock, severe hypoglycemia, metabolic acidosis, and respiratory failure.

Overdose treatment is the mandatory hospitalization of the patient, lavage (cleansing of toxins by introducing a special solution), activated charcoal, alkaline diuresis to obtain certain parameters of urine acidity. With the loss of fluid, the patient undergoes hemodialysis, measures to compensate for it. Symptomatic therapy is involved in the elimination of other signs.

Contraindications

The instructions for Aspirin say about the following contraindications, in which the use of the drug is prohibited:

• exacerbation of erosion or ulcers of the gastrointestinal tract;
• hemorrhagic diathesis;
• first and third trimesters of pregnancy, breastfeeding;
• bronchial asthma;
• hypersensitivity to acetylsalicylic acid, NSAIDs or other components of the drug;
• age up to 15 years;
• liver disease;
• decompensated heart failure;
• gastrointestinal bleeding.

Terms of sale and storage

Acetylsalicylic acid can be bought at the pharmacy without a prescription. The drug is stored at temperatures up to 30 degrees, away from the sun and children. The shelf life is five years.

Analogues

According to the active substance of the composition, pharmacological action in relation to the human body, the following analogues of Aspirin, produced by domestic and foreign firms, are distinguished:

• Thrombo ASS;
• Acecardol;
• ibuprofen;
• Antigripocaps;
• Aspeter;
• Citramon;
• Aspicod;
• Asprovit;
• Acecardine;
• Acelizin;
• Copacil;
• Paracetamol.

Price of Aspirin

In online pharmacies or pharmacy departments, the cost of Aspirin varies depending on the form of release and the number of tablets in the package. Approximate prices are listed below:

Video

Aspirin has been the most popular drug in the world for many years. At the first painful sensations, people drink a pill, or even more of this remedy. Recent studies by scientists have shown that this drug is not as harmless as previously thought. The benefits of aspirin for the body, of course, are, but the harm can be very noticeable. Therefore, it is necessary to remember the features of this medicine and the rules for its use.

Useful properties of aspirin

Aspirin is commonly referred to as a derivative of salicylic acid. One of the hydroxyl groups in the course of chemical synthesis was replaced by acetyl. As a result, acetylsalicylic acid was obtained.

The use of aspirin leads to a suspension of the production of prostaglandins. It is these hormones that are actively involved in inflammatory processes, contribute to an increase in body temperature. Acetylsalicylic acid prevents platelets from sticking together, which leads to the elimination of the symptoms of the inflammatory process.

Aspirin is useful in the following cases:

1. Takes away the heat. The drug affects the thermoregulation center located in the brain. Due to this, there is an expansion of blood vessels and increased sweating, which increases heat transfer. As a result, body temperature quickly returns to normal.
2. Promotes blood thinning, as it resists platelet aggregation. Thanks to this, it is possible to avoid cardiovascular diseases and the formation of blood clots.
3. Has an analgesic effect. The drug has an effect on mediators located in the area of ​​inflammation. In addition, it also affects the central nervous system.
4. Relieves inflammation. Due to the impact on small blood vessels, their permeability decreases, inhibition occurs by a factor that contributes to the development of the inflammatory process.
5. Reduces the likelihood of developing cancer. Scientists have found that people who take aspirin for a long time are less prone to cancer. To achieve this effect, the duration of its administration should be about three years.
6. Reduces the risk of developing Parkinson's and Alzheimer's disease. This action of aspirin only works for women.
7. The combination of aspirin and ibuprofen is also good for health. This leads to improved cerebral circulation, reduces the likelihood of stroke.
8. Reduces the risk of bronchial asthma.
9. In some cases, it can increase potency. This is true for men whose impotence is associated with vascular disorders.

Useful properties of aspirin are manifested only when it is taken correctly. Before using this drug, you should consult a specialist.

Why aspirin can be dangerous

The effect of aspirin on the human body can be negative. Among its negative properties are:

1. Negative effect on the gastric mucosa. In some cases, taking acetylsalicylic acid can provoke gastritis and peptic ulcer. Therefore, it is recommended to take the tablets only after meals and drink them with plenty of water.
2. May cause internal bleeding. This effect is due to the ability of aspirin to thin the blood.
3. Taking aspirin is strictly prohibited for flu, chicken pox and measles. This can provoke Reine's syndrome, which in some cases ends in death.
4. Taking the drug during pregnancy can lead to abnormalities in the development of the fetus.
5. It is forbidden to use aspirin at the same time as alcoholic beverages. This can lead to stomach bleeding.
6. Acetylsalicylic acid slows down the formation of prostaglandins in the kidneys. This can lead to impaired renal blood flow. If a person suffers from cirrhosis or heart problems, then in rare cases, taking aspirin provokes acute kidney failure.

Before specialists prescribe acetylsalicylic acid, its benefits and harms are weighed. Sometimes its negative influence can be stronger than useful qualities.

In order to minimize the harm to the stomach, aspirin is best taken in the form of tablets that dissolve in water. In this case, it is necessary to strictly adhere to the instructions for use.

Contraindications to taking acetylsalicylic acid

A healthy person can, in case of urgent need, drink aspirin fearlessly. But with health problems, you need to be careful. It is forbidden to take the drug in the following cases:

• Individual intolerance to the drug.
• Bronchial asthma, as the situation is likely to worsen.
• Unstable blood pressure.
• Liver diseases and suspicions of their presence.
• Serious abnormalities in the work of the kidneys.
• Pregnancy and breastfeeding period.
• Influenza, chickenpox and measles.
• Age up to 15 years.
• Gout.
• Alcoholism.

In the presence of such diseases, taking acetylsalicylic acid is harmful. Replace it with another remedy that is gentler on the body.

Permissible dosage

In order for the medicine not to cause harm to health, remember how much you need to use it. Exceeding the recommended amount can have negative consequences. You can drink tablets according to the following scheme:

1. Adults can take no more than 500 mg of acetylsalicylic acid at a time. The maximum daily dose is 3000 mg. It must be divided into several equal doses so that at least four hours pass between them. The duration of such treatment is not more than five days. As a means to thin the blood, the drug is recommended to be taken at night.
2. For children over 15 years of age, a single dose is 250 mg. At the same time, it is forbidden to consume more than 1500 mg per day.

You can't drink aspirin every day. Even in the treatment of cardiovascular diseases, it is consumed once every two days. Exceeding the permissible dosages is fraught with serious consequences.

The exact dosage in the treatment of a particular problem should be determined by the doctor. Remember that self-medication is dangerous to health.

Overdose

In the case of uncontrolled use of the drug or exceeding its permissible amount, symptoms of poisoning appear. In case of a single overdose, the following symptoms appear:

• Attacks of nausea followed by vomiting.
• Dizziness.
• Increased fatigue, drowsiness.
• Noise in ears.
• Tachycardia.
• Rapid breathing.
• Wheezing in the lungs.

If such signs appear, the use of the drug should be discontinued. Be sure to consult with a specialist.

In the case of a systematic excess of the permitted amount of aspirin, a state of chronic overdose develops. It may be accompanied by the following problems:

• Significant hearing loss.
• The appearance of hallucinations.
• pathological bleeding.
• Convulsions.
• Reinforced sweat compartment.
• Unquenchable thirst.
• Loss of visual acuity.
• Confusion of consciousness.
• Feverish state.

In this case, emergency medical intervention is necessary. It will require detoxification of the body and a long recovery period. In severe cases, aspirin poisoning can lead to cerebral edema and death of the victim. Therefore, the sooner you seek help, the greater the likelihood of a favorable outcome.

Useful properties of aspirin for external use

Not everyone knows that aspirin can not only be taken orally, but also used to treat hair and skin. Among the most common and effective methods of its application are the following:

1. As a peel. Based on aspirin, an effective face mask is prepared that perfectly removes impurities and dead skin cells. For its preparation, several tablets of the medicine are crushed and the resulting powder is stirred into a small amount sour cream. If the skin is oily, then it is better to replace sour cream with honey. This mask is applied to the face and kept for about 15 minutes.
2. For the treatment of inflammation on the skin: acne, pimples, boils. To prepare a healing agent, it is enough to dissolve an aspirin tablet in water and apply to problem areas. After three minutes, the remnants of the product must be washed off.
3. Restoration of shine and health of hair. To do this, before washing your hair with everyday shampoo, rinse your hair with water with aspirin dissolved in it. For one liter of water you need 6 tablets.
4. Elimination of calluses. With the help of an aspirin-based compress, it can effectively cope with calluses. To prepare it, you need to mix a teaspoon of lemon juice with the same amount of water. The resulting liquid should be mixed with six crushed aspirin tablets. The prepared paste is applied to the corn and wrapped in plastic wrap. Such a compress must be maintained for at least 15 minutes. After that, rinse and treat the skin with any nourishing cream.

When properly used judiciously, aspirin will provide health benefits. Before starting such therapy, it is necessary to consult a doctor and identify possible contraindications. Carefully monitor the dosage of the drug.

According to The Daily Telegraph. It seems that scientists nevertheless decided to get to the bottom of the truth, and if there are questions about its 100% effectiveness against heart disease, why not talk about cancer in connection? A new study by scientists at the University of Oxford has shown that this medicine, if taken daily for 3-5 years, can reduce the risk of developing by up to 30%. In this case, the drug not only stops the progression of the disease, but also the spread of metastases. In particular, taking 75 mg of aspirin per day for five years or more reduces the risk of developing bowel cancer by a quarter, and mortality from this disease by a third.

We also know that aspirin thins the blood by affecting platelets, so, again, it is prescribed for people with cardiovascular disease, it is also prescribed for the prevention of high blood pressure and diabetes. In addition, aspirin is widely used to maintain blood clotting processes and prevent recurrence. It is prescribed for migraine, cataract patients and preeclampsia of pregnancy. So should the elderly (who are not contraindicated in the drug) - the main risk group subject to serious - primarily heart and cancer diseases - take it every morning, like a pill for all diseases?

Professor Peter Rothwell, who leads the Oxford team, says yes. And Professor Gordon McVie of the European Institute in Milan confirms: “There is no doubt that aspirin is cheap and effective.” Peter Elwood, professor of epidemiology at the University of Wales, agrees with them, and is even more confident in the miraculous properties of this drug: "Taking aspirin every day, you increase your chances of a long and productive life, preventing serious diseases."

One of the UK's leading cancer experts, Professor Karol Sikora, says the preventive part of aspirin's miraculous effect has certainly been proven, but he himself is in no hurry to take the drug. Why - and he does not know, he does not have a clear answer. And he, so indecisive, is not the only one among British doctors. One day, Sikora, who was attending a thematic conference in the United States on cancer, asked his colleagues: “Do you take aspirin as a preventive measure for serious diseases?” - 60% answered yes. And at a conference in Britain, only 5% of doctors answered yes to a similar question. Cause? Karol Sikora believes that Americans are by default more concerned about their health than Europeans.

Side effects associated with regular aspirin use are a major risk factor for those who prescribe it for themselves as a panacea. The most important problem that has been talked about lately is disruption of the gastrointestinal tract, which can manifest itself in the form of pain, and in the most severe cases, aspirin can cause. “No one can guarantee that you will not experience this when taking this drug,” says Professor Sikora. “If you do not have an ulcer or gastritis in your anamnesis, in all likelihood, side effects will not appear. But if you experience stomach discomfort within a week or two of starting aspirin, talk to your healthcare provider.”

In addition to peptic ulcer disease, other contraindications include hemophilia or a bleeding disorder, and aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and diclofenac. People with asthma, liver disease, kidney disease, digestive problems, pregnant and lactating women should also take aspirin with caution.

But if you still decide to start taking this medicine as a preventive measure, then a natural question arises - when, at what age? Doctors believe that this is definitely worth doing to older people. For example, Dr. Sauvra Whitcroft, a consultant gynecologist at Guildford, recommends aspirin for menopausal women and older, who can take a low daily dose of no more than 75 mg. In this way, Wheatcroft explains, it is possible to reduce the risk of cardiovascular diseases, including, possibly, dementia, since aspirin, by thinning the blood, reduces the likelihood of microscopic blood clots in the blood vessels. It is also known that in women with age, estrogen levels gradually decrease, which can provoke a risk of developing cancer, so taking this drug may be effective. Should middle-aged people take aspirin? This question is still open, if only because cancer has no age restrictions.

Aspirin is a “folk” medicine with many prescriptions: it lowers the temperature, thins the blood, and relieves headache (tooth) pain. Also, this wonderful pill has been taken since the 70s of the last century for the prevention of heart attacks, strokes and oncology. And the housewives have long managed to use it even in conservation. An inexpensive and familiar medicine, tested by time: the date of invention is 1838.

Acetylsalicylic acid is still a widely used drug. It is an analgesic and anti-inflammatory drug used to treat:

• migraine;
• fever;
• neuralgia;
• rheumatism.

Cases of childhood illness after taking aspirin during the flu put the antipyretic functions of this drug in second place.

The beneficial properties of aspirin include the antithrombotic and cardioprotective properties of acetylsalicylic acid.

Prevention of thrombosis and cardiovascular diseases

Suppressing platelet aggregation (through inhibition of the production of thromboxane A2) and the synthesis of prostaglandins, acetylsalicylic acid prevents the development of thrombosis and cardiovascular pathologies.

Today, aspirin is often used as a prophylaxis against thrombosis and its associated dangers to the heart and blood vessels.

For the discovery in 1971 and evidence of the diluting and cardioprotective properties of acetylsalicylic acid, John Wayne, an English pharmacologist, received the Nobel Prize in 1982.

Prophylactic administration of small doses of acetylsalicylic acid reduces the risk of thrombosis in the coronary and cerebral arteries, which prevents heart attack, ischemic stroke and other cardiovascular diseases.

Chewing an aspirin tablet for myocardial infarction gives the patient a chance to survive and is used in first aid.

Controversies: swine flu, thrombosis and aspirin

A few words about the new swine flu season, in which, according to the medical standard protocol, aspirin is not recommended.

In 2016, by the way, it leads not only to pneumonia, but also to thrombosis.

Leonid Zhabotinsky died from a complication of swine flu - thrombosis of the intestinal arteries. Maybe acetylsalicylic acid, on the contrary, would have saved the weightlifter?

With contraindications to aspirin, other drugs should be used for thrombosis:

• Warfarin, phenylin, etc.

When choosing a medicine, you need to carefully study its composition, since a number of modern thinning drugs are based on the same acetylsalicylic acid: for example, cardiomagnyl, aspecard, cardopyrin.

Cancer prevention with aspirin

Oxford University professor Peter Rothwell, having examined a large group of patients, found that the constant intake of acetylsalicylic acid leads to a decrease in the incidence:

• cancer of the pharynx and esophagus;
• bowel cancer;
• lung cancer;
• colon and rectal cancer.

Aspirin was taken for 5 years in small doses: 75 - 100 mg.

Later, the experiment was repeated on specific tumors and found out the real effect of aspirin on tumors of the gastrointestinal tract - the likelihood of cancer was reduced by 20%. A decrease in the likelihood of cancer of other organs (breast, lung, etc.) when taking aspirin has not been proven.

The short duration of the effect was also established: as soon as the drug was stopped, the risk of developing cancer resumed.

Long-term prophylaxis with acetylsalicylic acid, even in small doses, can lead to intestinal gastroduodenopathy, duodenal and gastric ulcers, and gastrointestinal bleeding. Therefore, it is necessary to periodically take protectors for the gastrointestinal tract and monitor the level of platelets in the blood.

When is aspirin prohibited?

What is a benefit - the thinning properties of aspirin become deadly in the presence of:

• ulcers of the stomach or intestines;
• internal bleeding;
• hemophilia;
• thrombopenia;
• impaired vascular permeability;
• allergies to aspirin.

All these pathologies are contraindications for taking the drug.

• Acetylsalicylic acid is strictly prohibited for uterine bleeding, heavy menstruation, decaying tumors.
• Taking aspirin with blood clotting disorders, inelastic vessels can cause extensive hemorrhages, including in the brain.
• An allergic reaction to salicylates often manifests itself in the form of bronchial asthma, and one tablet is enough for the development of an allergy.

Myths and misconceptions

One of the misconceptions common among the population: aspirin irritates the mucous membranes due to the presence of acetylsalicylic acid in it.

In fact, acetylsalicylic acid has nothing to do with the side effects of the drug on the gastrointestinal tract - this action is characteristic of absolutely all drugs from the NSAID series, which include aspirin.

The technique of any NSAID is the blocking of cyclooxygenase (an enzyme involved in the production of prostaglandins that cause inflammatory processes).

There are two types of enzyme - COX-1 and COX-2.

In addition to the synthesis of prostaglandins, COX-1 also benefits - it protects the mucous membranes of the gastrointestinal tract, ensuring the proliferation (division) of epithelial cells.

Most drugs (including aspirin), except for selective ones that act selectively, block both types of enzyme, which leads not only to the relief of the inflammatory process, but also to the depletion of the protective mucous layer of the gastrointestinal tract and the subsequent development of erosion phenomena.

Selective drugs (movalis, nimesulide, celecoxib) inhibit only COX-2. They are less detrimental to the gastrointestinal tract, but also have side effects. Such NSAIDs are intended for long-term use and are used mainly for diseases of the joints and spine.

Myth 2: A coated aspirin tablet with additives is less dangerous for the stomach and intestines than a regular one.

This bluff was intensively spread by pharmacologists, releasing all kinds of expensive “soft” action aspirin - in a shell, mixed with other elements, in particular, with magnesium hydroxide:

• aspirin cardio,
• cardiomagnyl,
• aspecard and others.

In reality, despite the protective shell of the tablets, the harm from them to the stomach and intestines is exactly the same as from a regular aspirin tablet: the side effect does not come from direct contact of the drug with the surfaces of the gastrointestinal tract, but from its absorption into the blood. Therefore, regardless of the form in which the NSAID will be taken (intramuscularly, intravenously, orally or in the form of an external gel), only the absorption rate will be different - the side effects will remain the same.

Conclusion: everything is relative

• it is dangerous with the flu;
• it irritates the mucous membranes of the gastrointestinal tract;
• it causes bleeding...

As a result, the drug is unwittingly considered almost the most dangerous of all NSAIDs.

In fact, this medicine has a lot of useful properties, as you have seen, and contraindications are relative:

• The danger of the flu comes in the form of a rare Ray's syndrome in children.
• The danger of inflammation and ulceration of the mucous membranes is no more than when taking other NSAIDs.
• The properties of a blood thinner, being contraindications for clotting disorders and bleeding, become therapeutic indications for thrombosis and cardiovascular disorders.

Absolutely any medical drug has contraindications, and they should always be carefully studied, and not taken indiscriminately, guided by the principle: the more pills I drink, the healthier I will be.

Acitylsalicylic acid, or, as it is popularly called, aspirin, is a very common drug. By using this drug bring down the temperature, treat fever, anesthetize and even save themselves from a hangover.

But what are the harms and benefits of aspirin, not many people know. Most importantly, it helped! This is the wrong approach to drug treatment. Like other drugs, aspirin has a light and a dark side. In this article, we will consider such issues as the harm and benefits of aspirin, areas of application, restrictions and indications for use.

From the history

This type of acid has been known for a very long time. How to get it? From willow bark. Its healing and analgesic properties were noticed by Hippocrates and medieval herbalists. But willow was a valuable raw material for light industry, so it was forgotten in the field of pharmaceuticals for several centuries.

Whom to thank for the re-emergence of aspirin? The triumphant return was organized by Napoleon during the blockade of Europe. The problem was that they stopped importing quinine, which was popular among antipyretics. Then aspirin treatment came to replace it, only at that time it was known as But the taste of this remedy left much to be desired, and it irritated the mucous membranes.

How did the name "Aspirin" come about? It all happened in 1899. Felix Hofmann obtained a pure derivative of salicylic acid. Then a German company patented it and gave the name "Aspirin".

Application

Initially, the drug was used in the form of a powder, but over time it gained popularity. What are the harms and benefits of aspirin? To begin with, it was originally prescribed to patients who suffered from inflammation of the pleura and bladder. But later they noticed that it helps with other diseases, such as gonorrhea or tuberculosis.

The benefits of aspirin are certainly great. Why is he so versatile? Everything is explained very simply: every human cell has a protective shell. When under any influence it breaks through, is released arachidonic acid. Together with other enzymes, it signals a breakdown (fever, fever, inflammation). Is it possible to drink aspirin in such cases? Of course, it reduces the release of enzymes, thereby inhibiting inflammatory processes.

Cardiovascular diseases

Aspirin helps with a large number of diseases, influenza and acute respiratory infections are not limited. For example, let's take cardiovascular diseases that are very common in our country. Aspirin is often used to thin the blood. How to take and how long the course of treatment lasts, we will describe a little later.

The thing is that acetylsalicylic acid is able to thin the blood, thereby reducing the risk of blood clots, and as a result, it significantly reduces the risk of heart attacks and strokes. Note that a large dose of aspirin can help with a heart attack that has already happened. It reduces mortality by twenty-three percent.

Crayfish

The results of a study by American scientists revealed another useful property of acetylsalicylic acid. They describe how to take aspirin for a year. If you use this drug for a year, the disease does not progress, the tumor shrinks, and the risk of metastases is significantly reduced.

There is one "but": the study of aspirin in this area is not yet sufficiently supported by facts, so it cannot be included in anticancer therapy.

Pregnancy

The harms and benefits of aspirin do not apply equally to all populations. We suggest you separately study the effect of aspirin during pregnancy.

Any drug you take can harm the mother and unborn baby during pregnancy. Even the most innocuous drugs have restrictions or warnings about taking expectant mothers. Even vitamins, and those are not always allowed, and not any.

Aspirin is very difficult to call a safe remedy for a pregnant girl, but many doctors prescribe it for prevention. How to understand them? The thing is that acetylsalicylic acid can harm only in the first and third trimesters.

Risks

Why these particular periods? Everything is explained quite simply. In the first trimester of pregnancy, the formation of the internal organs of the baby occurs, so aspirin can harm this process. In the third trimester, the risk is due to the fact that it thins the blood, as a result of which there may be a large loss of blood during childbirth.

Some doctors do not recommend taking this drug to their wards, so they find a less dangerous replacement for it. Why? Because aspirin has an aggressive composition and has many side effects. As for the question: "Benefits of aspirin and harm, what more?" - it's up to you to decide. The reverse side of aspirin is presented below.

Side effects

The following are common:

• nausea;
• diarrhea;
• anorexia;
• impaired liver / kidney function;
• the formation of asthma;
• anemia;
• leukopenia;
• ulcerative lesions of the gastrointestinal tract;
• bleeding;
• hearing loss;
• swelling.

Harm during pregnancy

• the risk of miscarriage;
• complications during pregnancy;
• overwearing;
• risk of placental abruption;
• cardiac and pulmonary complications in a child;
• bleeding during childbirth.

Why do pregnant women need aspirin?

If you are used to using this drug for headaches, fever, then it's time to give it up. A good substitute would be safe during pregnancy paracetamol.

However, some people simply need to drink aspirin if, for example, in these cases, the child does not receive oxygen well, which threatens with a miscarriage. If a woman has found this problem or is at risk, then a quarter of an aspirin tablet is prescribed per day.

It is also prescribed for varicose veins, but there are also less dangerous drugs, for example, Curantil. If the situation is not critical, then instead of drug treatment, it is recommended to use foods that thin the blood: cranberries, carrots, beets.

Aspirin for blood thinning: how to take, dosage

Often in colloquial speech there is a concept Do not take everything literally. Platelets are responsible for blood clotting. Over time, strong hormonal changes occur in the human body. Substances appear in the blood that affect the rate of platelet aggregation, which leads to the formation of blood clots (thrombi). They are the cause of sudden death of people.

It is necessary to think about this issue at the age of forty. Taking aspirin daily reduces the risk of heart attacks and strokes.

Note that many do not have enough patience for all the treatment, they finish the course earlier than expected. But only daily and long-term use of drugs containing aspirin will help in this problem.

The choice of medicine should be given to the doctor, only he will be able to choose the right drug that will not harm your health. Who should pay special attention? People who have a family history of heart attacks and strokes. Hemorrhoids and varicose veins are also signals.

"Aspirin": instruction, price

Dosage and method of application depends on the purpose of the reception. If we are talking about prevention, then it should be taken for life when a certain age is reached. You need to drink one tablet in the evening with water. Why drink at night? It is at this time of day that the likelihood of blood clots is high. In emergency situations, the tablet must be chewed and placed under the tongue.

The daily dose for prevention is 100 mg, for treatment - 300 mg. As a rule, aspirin is sold in a pharmacy with a dosage of 500 mg, so you should be careful. Overdose can aggravate the overall clinical picture and lead to an increased rate of blood clots.

Are there analogues for this drug? Definitely yes:

• "Aspecard";
• "Cardiomagnyl";
• "Warfarin".

To thin the blood, you can not limit yourself to taking aspirin. You need to seriously rethink your diet. It should include fruits, vegetables, berries, fish, a large amount of liquid.

Prices for acetylsalicylic acid range from one hundred to five hundred rubles.