What is better to use Pancreatin or Festal? "Festal" from what? Instructions for use, composition, analogues, dosage. Which is better to use: "Festal", "Pancreatin" or "Mezim"

What is better Festal or Pancreatin to eliminate digestive problems, this question was asked by many of us who have encountered such problems in our lives. Everyone strives to choose for himself only an effective and efficient means.

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Problems with the digestive system can manifest themselves with various symptoms, but in most cases, patients complain of the following symptoms when they see a doctor:

  • bouts of nausea and vomiting;
  • the appearance of heartburn;
  • pain in the abdomen.

Gastrointestinal problems can present with a variety of symptoms.

To relieve symptoms, many prefer drugs such as Mezim, Festal or Pankeatin. Despite the fact that these drugs are known to everyone, not everyone knows what the difference between Festal and Pancreatin is.

Both of these drugs are able to relieve a person of unpleasant symptoms in a short period of time, in addition, these drugs are rightfully considered completely harmless and do not cause side effects. This is primarily due to their composition, which consists of the following components:

  • talc;
  • hemicellulose;
  • sodium chloride;
  • components of bile.

All of these components are aimed at improving and normalizing the functioning of the digestive system.

Pancreatitis is very often used by people who, for one reason or another, suffer from pathologies associated with digestion. The benefits of this drug are many. This is primarily the composition of the shell, as well as the amount of active substances in its structure, due to which side effects in the process of administration almost never cause side effects.

"Pancreatitis" is an effective remedy, but a doctor's consultation is required before taking

Despite the huge number of advantages, it is strictly forbidden to use Pancreatitis on your own without prior consultation with a specialist.

In order to get rid of problems with digestion, Festal has been used for quite a long time. This drug is preferred by many people suffering from digestive problems.

Due to its unique composition, it is Festal that is able to break down carbohydrates in the small intestine, normalize its microflora, and also prevent bloating and promote the absorption of food.

As long-term practice shows, Festal has the following advantages:

  • stimulates the production of bile;
  • accelerates metabolic processes;
  • stimulates the production of enzymes;
  • normalizes the gastrointestinal tract.

Festal is able to normalize the intestinal microflora

But since each drug has its own specific features and contraindications, it is imperative to consult a specialist before use.

In order to determine which drug is better than Festal or Pancreatitis, it is necessary to conduct a comparative analysis of these drugs and, based on this, the following conclusions can be drawn:

  • these two preparations contain a number of enzymes that are aimed at stimulating the production of active substances by the body and normalizing digestion. As for the differences, they are primarily due to the fact that they have a different composition of the outer shell. In addition, drugs have different functional features and have different effects on the digestive system;
  • despite the fact that many medical professionals believe that these drugs are similar to each other and are prescribed in their alternation, their difference lies in the fact that when using Pancreatitis, patients do not experience side effects at all, which cannot be said about the use of Festal , the use of which very often ends with the occurrence of side effects.
  • also another difference between Pancreatin and Festal is their cost. I would like to note that it is Pancreatin that is about three times cheaper compared to Festal;
  • many experts still prescribe Festal when prescribing complex treatment, because it is he who is considered the most effective and effective, despite the tangible similarity with pancreatin.

The doctor must decide on the choice of drugs

From all of the above, we can conclude that both drugs do an excellent job with problems associated with digestion. But in turn, each of them has its own advantages and disadvantages, and can also be contraindicated in each case individually, therefore self-medication is strictly prohibited and it is mandatory to consult a doctor before use.

Two well-known drugs, such as Festal and Pancreatin, are prescribed if a person is diagnosed with digestive problems. By and large, these are identical drugs and have almost the same indications for use.

Pancreatitis is prescribed in the following situations:

  • with chronic pancreatitis, if it is in a stable stage of remission;
  • after irradiation;
  • with a disorder of the stool of non-infectious origin;
  • dyspepsia;
  • Remheld's syndrome;
  • pancreatectomy;
  • resection of the digestive organs.

After the examination, the doctor will be able to choose the right drugs for treatment.

Note! Among other things, pancreatitis is also prescribed for preventive purposes, in order to improve the process of digestion of heavy foods, and even if a person leads a sedentary lifestyle. Also, it is pancreatin that is prescribed in preparation for surgery and ultrasound examination of the abdominal organs.

In turn, Festal has the following indications for use:

  • with diffuse liver diseases;
  • in preparation for ultrasound;
  • prolonged immobilization;
  • insufficiency of exocrine function;
  • chronic pancreatitis;
  • to improve digestion;
  • sedentary lifestyle.

But, like all other drugs, Festal and Pancreatitis have contraindications for use, which are as follows:

  • it is not recommended to use these drugs in case of stagnation in the intestines;
  • chronic disease of the pancreas;
  • intolerance to one of the components;
  • empyema of the gallbladder;
  • complex liver diseases;
  • noninfectious hepatitis.

Drugs should not be taken with complex liver diseases

Despite all of the above, even for preventive purposes, it is not recommended to accustom your body to either Festal or Pancreatitis. At the first signs, you should immediately seek medical help, since self-medication never brings the desired results, but rather can cause serious complications.

The overwhelming majority know firsthand problems with digestion and feelings of heaviness in the stomach. In order to alleviate these symptoms, many different drugs are currently on the pharmaceutical market. The most common of them is still Festal and Pancreatin, as well as various analogues of these drugs.

The analogues of Festal and Pancreatin include the following drugs:

  • mezim;
  • enzistal;
  • creon;
  • allochol;
  • panzinorm;
  • microzyme;
  • penzital.

Now let's compare analogues with their originals and understand their advantages and disadvantages. First of all, we will determine what is better Mezim, Festal or Pancreatin. Currently, Mezim is all the time on hearing, it is often advertised and many prefer this particular drug. Compared with Festal and Pancreatitis, Mezim is suitable even for people who suffer from gallstone disease. But in order to more accurately decide which of these remedies is suitable in a particular case, you need to consult a doctor.

"Mezim" - as an alternative method of drug treatment

No less popular is Enzistal. It is completely identical in composition to Festal and has exactly the same indications and contraindications, so it can rightly be called a worthy analogue.

As for Creon, this drug is different in that it contains a larger amount of pancreatin, and also has a slightly different form of release and is offered for sale in the form of gelatin capsules, due to which the most productive digestion of food occurs.

As for all the drugs listed above, despite the fact that they are analogues, they all have some differences and only a qualified doctor specializing in the treatment of these pathologies can answer the question of which is better panzinorm, mezim, festal, creon or pancreatitis.

Currently, there are many analogues, but which drug to use should be decided only by the attending physician. Otherwise, it can lead to serious consequences. Before replacing a drug prescribed by a doctor with an analogue, consult a specialist and thus you can protect your health from the development of complications.

Conclusion

If we draw a conclusion from all of the above and carefully compare these two drugs, we can conclude that there is not much difference between them. In addition, there is no difference in which remedy will be used to treat digestive problems. Regardless of which of these drugs or their analogues will be used to get rid of symptoms, the main thing is that this should be done after consulting a doctor. Since only a professional, after carrying out certain tests and studies, can accurately determine the cause and make an appropriate diagnosis and, based on this, select a drug and its dosage. In no case should you self-medicate, as well as replace the prescribed medicine with an analogue.

Recommendations from friends and work colleagues, persistent advertising, advice from a pharmacist behind a pharmacy counter - all these sources of information about medicines often contradict each other and cannot always help with the choice. So all the same - Festal or what is safer and more efficient?

Festal or Mezim - sometimes it's hard to choose

The Gastroenterologist's Handbook claims that both of these drugs are enzyme drugs that normalize the digestive process. If we consider medical indications and cases of use in more detail, then for them they will be as follows:

  • Insufficient production of digestive enzymes by the pancreas;
  • Condition after surgery on the pancreas, as well as after resection of the stomach or part of the intestine;
  • Consequences of radiation therapy;
  • dyspepsia;
  • Errors in the diet, changes in its qualitative composition, an increase in volume;
  • Difficulty chewing with maxillofacial fractures, missing teeth;
  • Forced immobility in case of injuries and serious illnesses;
  • Cystic fibrosis is a genetically transmitted disease, manifested by a lack or absence of enzymes.

For Festal, medical indications, in addition to the above violations of the function of the pancreas, are additionally:

Both of these drugs are recommended for use before ultrasound and x-ray examinations of the digestive system. That is, Festal or Mezim compensate for the deficiency of pancreatic enzymes, help digest food in situations that deviate from the standard.

Comparing the dosage form and composition

Mezim: release form - tablets

Mezim is produced by the German pharmaceutical company Berlin-Chemie, while Festal is produced by the Indian pharmaceutical industry. The dosage form of Mezim is pink tablets with a characteristic odor, consisting of a core and a shell. also consists of a core and a shell, which have a different composition from each other. This drug is offered to consumers in the form of round white dragees with a subtle vanilla flavor. It is worth asking about the constituent active substances for a more objective picture. So, the composition of Mezim (in one tablet):

  1. Lipase - 3500 units (breaks down fats)
  2. Amylase - 4200 units (breaks down proteins)
  3. Protease - 250 units (breaks down carbohydrates)

These enzymes are the components of the active substance Mezim. In addition to it, there are excipients in the composition:

  • Microcrystalline cellulose
  • Carboxylmethyl starch sodium salt
  • colloidal silicon dioxide
  • magnesium stearate

The active substance of Festal is the same Pancreatin, consisting of enzymes:

  1. Amylase - 4500 units
  2. Lipase - 6000 units
  3. Protease - 300 units

Judging by the amount of Lipase, Festal should break down fats more actively than Mezim. In addition to enzymes, the active substances of Festal include:

  • Hemicellulase - 50 mg
  • Ox bile extract - 25 mg

Bile is the main difference between Festal and Mezim, its components stimulate the biliary function of the liver, gallbladder, and intestines. Hemicellulase, which is not present in Mezim, but present in Festal, breaks down plant fiber, normalizes the intestinal microflora.

The combination of bile and hemicellulose effectively breaks down carbohydrates, proteins, fats in the duodenum, increases the absorption of fat-soluble vitamins. Auxiliary substances are also different from those of Mezim, although this is not decisive for the consumer, except in cases of individual intolerance to these components:

  • Castor oil
  • Gelatin
  • Dextrose
  • Ethylvanillin
  • sucrose
  • Cellacephate
  • acacia gum
  • Glycerol
  • macrogol
  • Titanium dioxide

When choosing, you need to pay attention to the differences in their composition, the difference in active and excipients.

Compare side effects and contraindications

Festal: release form - tablets

Contraindications to the use of Festal due to the inclusion of bile in its composition, which adversely affects the state of the liver and gallbladder with their functional disorders, are:

  1. Hepatitis of various etiologies;
  2. Mechanical jaundice;
  3. Liver failure, other liver diseases, accompanied by elevated levels of bilirubin;
  4. (bile irritates the damaged esophagus);
  5. Individual intolerance to enzymes of animal origin.

The list of contraindications for the drug Mezim is much shorter, since it does not affect the function of the liver and gallbladder. This is acute pancreatitis and exacerbations of chronic, as well as individual intolerance to the components.

When choosing Festal or Mezim for the treatment of children, you need to consider that Festal is not used for use in children under 3 years of age. With regard to the use of these drugs in pregnant and lactating women, the use of Mezim is not recommended, since there are no research data, Festal in pregnant women is taken with caution.

Side effects when using Festal can be diarrhea, nausea. If high doses are used long enough, such complications from the urinary system as hyperuricuria, hyperuricemia are not excluded. In children in similar situations of overdose, irritation of the oral mucosa is possible. Side effects of Mezim practically do not differ from Festal.

After analyzing the contraindications of both drugs, we can conclude that their uncontrolled use is not so safe, and can have irreparable consequences, which means that Festal or Mezim should not be taken for a long time without consulting a doctor.

Compare how to use

Pancreatin - the active substance of both Festal and Mezim

The advantage of Mezim for use can be considered that the active substance of the drug is protected by a shell that dissolves under the influence of intestinal secretion, that is, it reaches its destination in full. This means that Mezim tablets cannot be divided into parts, chewed, crushed.

Also, they can not be taken simultaneously with other drugs, go to bed after taking Mezim, so that dissolution does not occur in the esophagus. The tablet is washed down with water, it is taken with food. Children's dosage - 50,000-100,000 units of lipase, adult - 150,000 units, in the complete absence of their enzymes - 400,000 units. The term of application is quite long, if necessary, up to several years.

The method and duration of application of Festal are almost identical to Mezim, however, the dosage for children, and the increase in the standard dose for adults, necessary for medical reasons, is calculated only by a doctor. In preparation for the study of the abdominal organs, Festal begins to be consumed 2-4 days before taking 2 tablets three times a day.

Both Mezim and Festal are available without a doctor's prescription. Mezim may be falsified, as it is very often counterfeited. In order to verify the opposite, you need to remove the top cover of the hologram on the package. An image of a stylized letter M should remain under it, this serves as proof of the authenticity of the drug.

If you have to face a choice - Festal or Mezim, you need to evaluate the indications and contraindications for use. You will have to be especially careful when choosing a drug for children and pregnant women. In the presence of chronic diseases, pathologies of the digestive system, especially the liver and gallbladder, consultation with a gastroenterologist or therapist is vital. With independent episodic use, do not exceed the dosage in order to avoid side effects.

About enzyme preparations for patients with chronic pancreatitis - in the video:


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Festal and Mezim are popular enzyme medicines. They are taken both for the treatment of diseases of the gastrointestinal tract, and to eliminate the symptoms of overeating. The active ingredient in both preparations is pancreatin, obtained from the pancreas of a pig.

Characteristics of Festal

Produced in the form of enteric dragees. Pancreatin is an active ingredient that contains digestive enzymes:

  • amylase - involved in the digestion of carbohydrates;
  • lipase - breaks down fats;
  • protease - breaks down proteins.

The composition also contains bile components and hemicellulose. Bile acids aid in the digestion of food. The hemicellulose enzyme is involved in the digestion of plant fiber.

After the use of Festal, the active ingredient is released in the small intestine, where it has a therapeutic effect.

The medicine is indicated for the following conditions:

  • disorder of exocrine function of the pancreas;
  • flatulence, non-infectious diarrhea;
  • irritable bowel syndrome;
  • diffuse liver diseases;
  • chronic gastritis, colitis, cholecystitis, duodenitis.

In patients without gastrointestinal pathologies, it is used to improve digestion.

The drug is indicated for diseases of the esophagus, as well as in preparation for ultrasound, x-ray examination of the abdominal organs.

Contraindications to the appointment of Festal:

  • hypersensitivity;
  • hepatitis;
  • acute pancreatitis;
  • exacerbation of chronic pancreatitis;
  • liver failure;
  • hepatic coma or precoma;
  • jaundice;
  • acute purulent inflammation of the gallbladder;
  • hyperbilirubinemia;
  • intestinal obstruction;
  • predisposition to diarrhea;
  • cholelithiasis;
  • age up to 3 years.

Pregnant and lactating women are prescribed carefully.


Side effects:

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  • allergic reactions (itching, skin rash, lacrimation, runny nose);
  • malfunctions of the digestive system (abdominal pain, nausea, diarrhea);
  • hyperuricemia, hyperuricosuria, irritation of the oral mucosa and anus (occur while taking an increased dosage).

Characteristics of Mezim

Mezim contains pancreatin. Pancreatin enzymes help digest proteins, fats and carbohydrates that play important role in many bodily processes.

The action of the drug is aimed at the production of its own enzymes internal organs. Bile begins to be actively produced, restoring the digestive process. This allows you to digest and assimilate even the most fatty, heavy food.

Mezim is produced in the form of coated tablets. It protects the active substance from the effects of gastric juice. Without such a shell, the therapeutic effect would be reduced.

The drug is indicated in the following cases:

  • diseases of the pancreas;
  • chronic pancreatitis;
  • flatulence, bloating, diarrhea;
  • cystic fibrosis;
  • pathology of the gastrointestinal tract and liver;
  • enzyme deficiency after surgery on the intestines or stomach;
  • preparation for diagnostic examinations.

The drug should not be used in acute pancreatitis, exacerbation of chronic pancreatitis, hypersensitivity. Acceptance by pregnant and lactating women is allowed. But it should be borne in mind that adequate research in these areas has not been conducted.

Most often, while taking the drug, the following side effects appear:

  • allergic reaction in the form of urticaria;
  • diarrhea, constipation, nausea, vomiting;
  • discomfort in the epigastrium.

Composition Similarities

In these drugs, the same active ingredient is pancreatin. But the number of enzymes is somewhat different. So, 1 tablet of Mezim contains:

  • 3500 units of lipase;
  • 4200 units of amylase;
  • 250 units of protease.

The composition contains auxiliary components:

  • microcrystalline cellulose;
  • sodium salt of carboxymethyl starch;
  • colloidal silicon dioxide;
  • magnesium stearate.

In Festal:

  • 6000 units of lipase;
  • 4500 units of amylase;
  • 300 units of protease.

Also included is:

  • 50 mg hemicellulose;
  • 25 mg ox bile extract.

Festal's auxiliary components are different:

  • Castor oil;
  • sucrose;
  • gelatin;
  • dextrose;
  • cellacephate;
  • ethylvanillin;
  • acacia gum;
  • titanium dioxide;
  • macrogol;
  • glycerol.

Thus, the composition of the drugs is the same. The difference is only in the enzymatic activity of enzymes and excipients. When prescribing Festal or Mezim, the doctor takes into account these features.


What is the difference between Festal and Mezim

The drugs have a number of minor differences:

  • Mezima contains fewer enzymes, so it is considered safer. The drug has a pronounced odor. The list of contraindications is short. contains no bile.
  • Festal has a pleasant taste, but it should not be used for a number of diseases. Large list of contraindications.

Medicines are produced by different manufacturers. Festal is produced by an Indian pharmaceutical company, Mezim is a German one. It is also important that Mezim is cheaper than Festal. Although prices in different pharmacies may vary.

What is better to use Festal or Mezim

Both drugs have long been used in gastroenterology and have proven themselves well, which makes the choice difficult. But based on numerous reviews of doctors and patients, we can conclude:

  • Mezim is well suited for long-term treatment of pancreatic diseases and restoration of digestion.
  • Festal should not be used in diseases of the liver and gallbladder. It is better to take this medicine for a short time.
  • Both drugs are excellent for overeating symptoms. But at the same time, one drug cannot be called a substitute for another.

Mezim and Festal are medicines, so only a doctor should prescribe them. When choosing, the severity of the disease and the individual characteristics of the organism are taken into account.

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The modern rhythm of life makes a person do everything "on the run" - meet, resolve business issues and return to work again. Returning home, take a shower and fall on the bed in order to get into the same wheel again in the morning.

There is sorely not enough time for a full-fledged meal, so food is also “on the run” - sandwiches, fast food, snacks, and only in the evening - “for the whole day”.

This rhythm leads to malfunctions of the digestive tract. In many cases, preparations containing enzymes come to the rescue. They help improve the digestion of food. Mezim and Festal are perhaps the most famous and sought after.

And if they are not in the pharmacy or there are certain contraindications? There is a way out - analogues and substitutes also effectively help to solve the problem.

Everyone should remember that there must be clear indications for taking enzyme preparations. Otherwise, you can bring the pancreas (it is its enzymes that are part of the agents under consideration) to complete atrophy.

Mezim or Pancreatin

Before figuring out which is better - Mezim or Pancreatin, it would be nice to know what is the difference between them. After all, an analogue is an analogue, but one drug is prescribed in each specific case.

Pancreatin is an enzymatic complex that is extracted from the pancreas of animals (cattle, pigs and poultry). It consists of:

  • Amylase, which breaks down carbohydrates;
  • protease processes proteins;
  • lipase - carbohydrates.

There is also a drug of the same name. But it is pancreatin that is part of all the means that promote digestion and supply the missing enzymes to the body. Pancreatin or Mezim should be chosen according to the number of active ingredients.

There are many drugs that include Pancreatin:

  • Festal;
  • Panzinorm;
  • Penzital;
  • Motilium;
  • Micrasim;
  • Creon;
  • Pangrol;
  • Enzistal;
  • Pancrenorm;
  • Panzim;
  • Ermital and many others.

But the most popular analogue of Pancreatin still was and remains Mezim. Although other drugs are in no way inferior to this "sweet couple".

What is the difference between drugs

The main difference is the concentration of the amylase enzyme. Usually this is the number in the name of the drug. Mezim Forte 10000 contains the same amount of amylase. Mezim Forte's analogues in concentration are Creon, Panzinorm and Micrasim with the corresponding number in the title.

  1. Creon and Micrasim 25000 is the highest concentration of the enzyme. The lowest is in Mezim Forte 3500.
  2. In addition to the concentration of amylase (respectively, other pancreatic enzymes), Mezim's analogues differ in the content of additional components. Festal, Enzistal and Digestal also have hemicellulose and bile.
  3. Mezim Forte substitutes can be produced in different pharmacological forms. These are coated tablets and gelatin capsules with micro-tablets inside.

Therefore, you can choose not only Mezim or Pancreatin, but also analogues, depending on the general condition, the cause of indigestion and the degree of damage to the pancreas.

Indications and application features

Before taking any enzymatic preparation, it is necessary to know about the cases when it is indicated for use.

Typically, such therapy is prescribed for the following ailments and conditions:

  • cystic fibrosis;
  • chronic pancreatitis against the background of enzyme deficiency;
  • pathology of the stomach of an inflammatory nature with digestive disorders;
  • diseases of the liver and gallbladder with disruption of the digestive tract;
  • bowel disease;
  • irradiation and resection of the above organs;
  • before an ultrasound of the abdominal organs or radiography of these organs;
  • binge eating;
  • alcohol intoxication.

Only in the last two cases can Mezim or Pancreatin or their analogues be taken independently. In all others, it is necessary to consult a specialist with the selection of an effective dosage. This is done on the basis of diagnostic measures to determine the condition of the pancreas.

If a person needs only temporary support, then the dosage will be negligible. If the gland does not work at all, then therapy is likely to be constant and in fairly high doses.

You should know that with diarrhea caused by even a banal overeating, bile-containing medicines cannot be taken. Therefore, the answer to the question - Festal or Mezim, will be decided in favor of Mezim.

It is necessary to take enzymatic agents during a meal, drinking a small amount of water or juice, but not an alkaline liquid. Once in the digestive system, the shell (on tablets or gelatin capsule) dissolves directly in the small intestine, where the action of enzymes is most necessary and important.

As we have already found out, Mezim analogues are very diverse both in terms of the number of pancreatic enzymes, and in the form of release and additional components. Consider the most common, well-known and affordable.

Pancreatin

Mezim and Pancreatin are "twin brothers". They are absolutely identical in composition, spectrum of action, contraindications and side effects. The drug is produced by domestic manufacturers, so it is the cheapest analogue of Mezim, but not at all the worst in quality. Therefore, if you choose between Mezim and Pancreatin, then the choice will definitely remain with the second.

Festal

If we talk about which is better - Festal or Mezim, then everything is not so simple. Enzistal is similar in composition and mechanism of action. The composition includes, in addition to pancreatic enzymes, also bovine bile, which improves the functioning of the liver and biliary tract.

Festal has a number of contraindications that are not listed in the Mezim instructions for use. According to reviews, this remedy also causes side effects in the form of diarrhea, sour belching, and in some cases heartburn.

This once again proves that the use of any medication must be agreed with a specialist in order to avoid trouble during treatment.

Creon

Creon is an expensive analogue of Mezim. It is available in the form of gelatin capsules, the shell of which dissolves only in the small intestine. The concentration of enzymes can be similar. But it is Creon Mezim that surpasses the drug with the maximum amount of amylase. That is, if large doses are necessary, preference is still given to Creon.

A drug is prescribed to restore the functioning of the digestive system, disturbed due to the intake of other drugs, as well as in diseases that are characterized by increased flatulence.

Pangrol

Pangrol is a very high-quality analogue of Mezim Forte, but at a slightly higher price. It effectively restores the work of the gastrointestinal tract in various pathologies, is indicated for diarrhea caused by insufficiency of the secretory functions of the pancreas. With an exacerbation of chronic pancreatitis or with an acute attack of a primary disease, it is not recommended to take it.

Other analogues and substitutes

Now let's dwell a little on less well-known, but no less effective drugs that can be called a substitute for Mezim. And let's start with the most highly concentrated.

  1. Mezim Forte 10000 or Micrasim 10000 are absolutely similar medicines. But our second "hero" is also available with an amylase dosage of 25000;
  2. Panzinorm 10000 has the same list of indications, mechanism of action and differs only in the size of the tablet;
  3. Penzital has a lower amount of amylase - 6000. It is indicated for the treatment of situational disorders of the digestive system, which it effectively copes with if the prescribed dosages are observed.

Mezim can be replaced with a drug such as Motilium. It does not contain Pancreatin in its composition, but it even has some advantages over enzymatic preparations, as it is able to stop vomiting attacks, copes with gas formation and bloating, improves gastric and intestinal motility, and promotes high-quality excretion of feces during stagnant processes.

Knowing how to replace Mezim, it will not be so difficult to make a choice, and unfamiliar names do not have such an intimidating effect on the patient's psyche. But it should be remembered that Mezim's analogues are cheaper than himself, and are not a way out of the situation, especially if the drug was prescribed by a specialist to solve certain problems.


Source: priponose.ru

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Today, the question remains, Festal or Mezim medicines - which is better?

Both drugs contribute to the absorption of food, especially in pancreatitis, cystic fibrosis, cystic fibrosis, preparation for ultrasound, x-rays, and also as part of the complex therapy of certain diseases.

Comparison of these drugs is necessary because they have different composition and limitations in use.

Composition of medicines

Enzymatic drugs are necessary for patients suffering from diseases in which there is a decrease in the external secretion of the pancreas. The use of preparations containing pancreatin is also necessary during feasts and holidays. Therefore, it is important to find out what is better to use - Festal or Mezim.

First you need to find out what the composition of these drugs. Both drugs include pancreatin, which is extracted from the pancreas of cattle. It contains enzymes:

  • lipase - for the breakdown of lipids;
  • amylase - for the absorption of carbohydrates;
  • protease - for the digestion of proteins.

These drugs need to be compared, because they have different auxiliary components. Below is a table with information about the release form and composition.

They also produce Mezim forte, which has a higher concentration of pancreatin.

Hemicellulose is necessary for the absorption of dietary fiber (fiber), which prevents flatulence and improves the digestion process. Bile helps break down lipids, vegetable oils, fat-soluble vitamins, and improves lipase production.

Indications and contraindications for use

Both drugs are used in violation of the exocrine function of the pancreas. They can be prescribed by a healthcare professional, but since they are sold without a prescription, anyone can buy them.

Festal and Mezim have the same list of indications. You can use dragees and tablets in such cases:

  1. With indigestion. This applies to healthy people who have eaten too much food, have problems with chewing function due to prolonged immobilization (immobilization of body parts) or wearing braces.
  2. With cystic fibrosis, cystic fibrosis or chronic pancreatitis. In these cases, the production of enzymes leads to even more inflammation of the pancreas.
  3. In preparation for ultrasound examination and radiography of the peritoneal organs.
  4. With complex treatment. These can be chronic dystrophic-inflammatory pathologies of the digestive tract, cholecystitis, poisoning, removal or chemotherapy of the stomach, liver, gallbladder or intestines.

Despite the general indications, Festal and Mezim have different contraindications. It is forbidden to use Festal in such cases:

  • with exacerbation of chronic and;
  • with non-infectious hepatitis;
  • with hepatic dysfunction;
  • with individual sensitivity to the components;
  • with an increased content of bilirubin;
  • with intestinal obstruction;
  • in childhood less than 3 years.

Compared to Festal, Mezim has much fewer restrictions:

  1. Acute pancreatitis at the stage of exacerbation.
  2. Hypersensitivity to drug substances.

Medicines are prescribed with extreme caution to pregnant women and nursing mothers.

Since there is no data on how the components of the drug act during pregnancy and the lactation period, they are prescribed when the benefits of use outweigh the possible negative consequences.

Instructions for use of tablets

Enzymatic preparations should preferably be taken with meals. Tablets and dragees must be swallowed whole with water.

The dosage and duration of the course of therapy is determined by the attending specialist on an individual basis.

The duration of taking medications ranges from a few days to a couple of months and even years in the case of substitution treatment.

There are some drugs with which you can not use Festal and Mezim at the same time. These include:

  • antacids that reduce the effectiveness of these drugs, such as Rennie;
  • Cimetidine, which enhances the effectiveness of enzymatic agents;
  • antibiotics, PASK and sulfonamides, since simultaneous administration with Festal or Mezim increases their adsorption.

Long-term use of enzyme preparations leads to a decrease in the absorption of drugs containing iron.

There are certain requirements for the storage of drugs. The packaging must be kept out of the reach of children. The temperature regime for Mezim is up to 30⁰С, for Festal - up to 25⁰С.

The shelf life of medications is 36 months. After the expiration of this term, the use of drugs is strictly prohibited.

Side effects and overdose

It is quite difficult to determine which remedy is better - Festal or Mezim. There are many positive reviews about both drugs. They are even used for weight loss for better absorption of food. When choosing an effective enzymatic agent, it is necessary to take into account the age, individual characteristics and concomitant pathologies of the patient.

An expert will tell you about enzyme preparations for pancreatitis in the video in this article.

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