The drug nootropil indications for use. Nootropil is an effective and safe replacement for Piracetam

In modern medicine, there are drugs that affect brain activity, improve thought processes, attention, and memory. These include the drug Nootropil. It is suitable for adults but also for children. The medicine will eliminate the problems that have arisen with study, help to concentrate, assimilate new information. Nootropil for children usually is prescribed to increase mental performance and delay speech development. In our review, you will find detailed information about the forms of release of the drug, available side effects, choosing the right dosage.

Nootropil increases concentration and learning efficiency.

Composition and mechanism of action

Nootropil is a drug from the group of neurometabolic stimulants. The main ingredient is piracetam. Auxiliary components are silicon dioxide, magnesium stearate, an additive called macrogol 6000. A solution for internal use (one of the release forms), also contains flavors, acetic acid and preservatives.

Piracetam affects the processes in the brain cells, provides communication between the hemispheres, prevents the adhesion of blood cells, increasing microcirculation in the vessels. Thanks to this component Nootropil has a beneficial effect on brain activity, helps to concentrate.

Indications

Children are prescribed medicine for the following problems:

  • decrease in learning ability;
  • previous ischemic stroke;
  • violations of the vestibular apparatus;
  • coma associated with trauma or intoxication;
  • cortical myoclonus;
  • cerebral paralysis;
  • oligophrenia.

The child cannot remember simple information or does not think well? The drug can help your baby!

Other indications for use are trauma during childbirth or during fetal development, congenital disorders of the central nervous system.

Manufacturer and release forms

Licensed manufacturer - YUSB Farshim S.A., Belgium. The drug is available in different forms, which makes its use more convenient:

  • Tablets. They have an oval shape, are enclosed in a white shell and are packaged in packs of 20 and 30 pieces.

Children older than three years can be given pills.

  • One package contains 60 white capsules. Each contains 400 mg of active ingredient.

The capsule should be taken with plenty of water.

  • Solution for internal use. Moms often call it syrup. It is available in 125 ml dark glass bottles, each comes with a measuring cup. 1 ml of the drug contains 200 mg of piracetam.
  • Injection. Sold in ampoules and is a colorless liquid containing 1 ml of 200 mg of the active ingredient.
  • Solution for intravenous use. In one package 4 bottles of a 20% solution of 15 ml each.

Piracetam injections are painless.

Nootropil the child is most often prescribed in the form of tablets or a solution (syrup) for internal use. The average price of one package of the drug in any form is 300 rubles.

Rules for use and dosage

Nootropil assigned to children only from 1 year. The dosage is selected by the doctor in accordance with the weight, age of the child and the characteristics of the disease. Instructions for use prescribes to take from 2.4 to 4.8 g of the drug per day. The medicine is given to children before meals. Tablets and syrup are recommended to be taken with water or juice.

Reception features:

  • For memory problems, the children's daily dose is 4.8 g.
  • A child with a brain injury - 2.4 g of the drug per day.
  • With poor learning Nootropil is recommended to take 3.3 grams per day.

If for some reason the child cannot take the drug orally, the doctor prescribes injections for him. The dose of the solution for intramuscular injection is calculated depending on the clinical picture and the age of the baby.

The duration of the course of treatment is at least 3 weeks. If by the end of this period there is no positive dynamics, the use of the drug is stopped.

Contraindications and side effects

Non-compliance with the dosage or an incorrect diagnosis can lead to side effects. They may appear as:

  • allergies;
  • pain in the head;
  • hyperkinesia;
  • nausea;

A possible side effect is abdominal discomfort.

  • digestive disorders.

When you stop taking the medicine or reduce the dosage, unpleasant symptoms usually disappear.

Contraindications to the use of Nootropil:

  • the age of the child is less than 1 year;
  • kidney failure;
  • transferred hemorrhagic stroke;
  • violations of hemostasis;
  • individual intolerance.

Give Nootropil to children with bleeding disorders with caution. You can not combine the reception of this drug with anticonvulsants and intended for the treatment of the thyroid gland.

Reviews

Feedback from Tatyana Anatolyevna (son Vitaly, 6 years old), Vladimir:

“We were diagnosed with autism. The child gets emotionally tired very quickly from the slightest overload, cannot concentrate during activities where mental effort is required. I have been giving him Nootropil since the beginning of September and I see that Vitalik is already coping with tasks much easier, preparing with pleasure for the New Year's party.

The effect of the drug is noticeable after a few weeks.

Feedback from Elena Sergeevna (daughter Sophia, 4 years old), Volokolamsk:

“Sonechka was prescribed Nootropil for the development of speech. She spoke very poorly until she was 3 years old. I don’t know if the medicine helped or what, but now the baby is babbling, building whole sentences. Even if her speech is not always clear, but the desire to speak pleases. We have already learned a few short rhymes with Sonya, which we could not achieve before. True, I noticed recently that the child has become irritable, whiny. I think this is due to the medicine, just in case, we will refuse further intake for now. ”

Severov M.N., pediatrician:

“Nootropil has a positive effect on the cerebral cortex, improves memory, stimulates speech development in children. It acts gently and effectively, is available in different forms, so you can choose the most convenient. I recommend to patients with Nootropil. If moms are confused by the price of a medicine, then you can find less expensive drugs with a similar effect.

Analogues

If the child has contraindications indicated in the instructions or needs a cheaper drug, the doctor will help you choose a remedy with a similar effect.

An analogue in composition is Piracetam - a medicine with the same active ingredient. It improves metabolic processes, microcirculation, cerebral circulation. The average price for a package containing 30 tablets is 60 rubles. It has a positive effect on attention, memory, intelligence, and increases mental and physical performance. The average price of a bottle of 100 ml is 300 rubles.

  • . The effectiveness of the drug is due to the vinpocetine that is part of it. Means improves cerebral circulation, reduces blood viscosity. The average price is 200 rubles per pack of tablets (30 pcs.).
  • - a drug based on aminophenylbutyric acid. It has a positive effect on brain function, improving attention, memory, normalizing blood circulation in the central nervous system. Phenibut relieves irritability, improves sleep. The cost of one package containing 20 tablets is 70 rubles.
  • - a drug produced in the form of a solution for injection. The active ingredient is a mixture of biologically active oligopeptides. Cerebrolycin has a complex effect on the cerebral cortex, activating mental processes and improving mood. The average price for 10 ampoules is 1000 rubles.
  • . The active substance of the same name. Normalizes the activity of the central nervous system, improves the quality of sleep. It is released without a doctor's prescription at an average price of 30 rubles. per package containing 50 tablets.
  • Nootropil is an effective drug for increasing brain performance, improving memory and attention. However, it cannot be considered harmless and used without the advice of a specialist. Any medicine for a child should be prescribed by a doctor.

    Irina Zykova

    Nootropil belongs to the group of nootropics. The main active ingredient. Recommendations on how to take Nootropil are individual in each case. The action of the drug is to accelerate and enhance mental activity by optimizing the functioning of neurons. In addition, the drug affects the speed of impulse transmission.

    The drug contributes to the activation of life-support metabolic reactions in the neuron by improving blood flow in them, and, consequently, improving the delivery of oxygen, glucose and many essential substances. Microcirculation is normalized by reducing the viscosity of the blood, its thinning, improving the functioning of red blood cells, their ability to change their shape due to the elasticity of the membranes.

    1. Severe degrees of impaired consciousness (coma).
    2. Psychoorganic disorders. Including pathological changes in memory in the elderly, impaired ability to concentrate, pathological changes in behavior.
    3. Therapy after stroke.
    4. Therapy for emotional disorders.
    5. To alleviate the manifestations of withdrawal symptoms in the treatment of alcohol dependence.
    6. With a decrease in learning ability in children with psychoorganic disorders.

    Release form and method of application

    The drug is available in the form of tablets (800 mg), capsules (400 mg), solution for intravenous administration 20% (125 ml), injections 20% (5 ml). How to drink Nootropil? Capsules, tablets are taken before or during a meal. Drink water. For adults: 30 - 160 mg / kg of body weight per day. The dose is divided into 2-4 doses.

    If the doctor has not given other recommendations on how to take Nootropil to improve memory, then for psycho-organic causes of such disorders, it is recommended to take 4.8 g / day. The course of this dosage is an average of a week. Supportive 1.2-2.4 g / day.

    Treatment of postischemic cerebral changes: 4.8 g/day.

    Severe disturbances of consciousness (): start with 9-12 g / day, then move on to the maintained numbers - 2.4 g / day. The course is about 21 days.

    Dizziness, impaired coordination and balance: 2.4-4.8 g / day.

    With a decrease in learning: 3.3 g / day. Admission can continue throughout the academic year.

    In the treatment of alcohol dependence: in the acute period of abstinence with the abolition of alcohol, 12 g / day, then 2.4 g / day. If the patient cannot take Nootropil orally, the method of application can be changed to intravenous.

    In hepatic and renal insufficiency, it can also be prescribed. How much to take Nootropil for kidney pathologies depends on creatinine clearance and is selected individually by the attending physician. For liver pathologies, dose adjustment is not required. In hepatic insufficiency, dosages are adjusted taking into account creatine clearance.

    Side effects and contraindications

    Side effects of Nootropil are extremely rare. Possible: nervousness, deterioration of the emotional background, slight drowsiness. Complications occur with prolonged use of the drug. Side effects of Nootropil are also manifested by headache, feeling, sleep disturbance, increased libido, hallucinations, anxiety, nausea, impaired stool, allergic reactions with Piracetam intolerance.

    Contraindications:

    1. The use of the drug is contraindicated in case of insufficiency of kidney function with creatinine clearance below 20 ml / min, children under one year of age, with hemorrhagic stroke, intolerance to Piracetam, Pyrrolidone.
    2. Pregnancy and feeding. There are no reliable data proving the safety of the drug in pregnant women; studies have not been conducted. The main active ingredient has the ability to penetrate both through the placenta and into the milk of a nursing mother. When taking Nootropil, 70-90% of its volume, determined in the mother's blood, is determined in the baby. Therefore, it is practically not prescribed to pregnant women. Only in cases of vital importance. Lactating women are advised to stop breastfeeding for the duration of the drug.

    The use of the drug in parallel with the use of alcohol does not change the concentration in the blood of either one or the other. The drug is used with caution in case of changes in the blood coagulation system, significant bleeding, with planned operations. With prolonged use of the drug, it is recommended to monitor laboratory renal parameters. It is not recommended to use Piracetam during activities that require a quick reaction, driving a car.

    No specific symptoms of overdose have been identified. Intoxication symptoms are possible: nausea, vomiting, abdominal pain, stool disorder, diarrhea with blood is possible. In such cases, gastric lavage, stimulation of vomiting, hemodialysis are carried out.

    The composition of the medicinal product Nootropil

    tab. po 800 mg, № 30 UAH 29.82

    Piracetam 800 mg

    No. UA/0054/04/02 from 02.08.2004 to 02.08.2009

    tab. po 1200 mg, № 20 UAH 37.1

    Piracetam 1200 mg

    Other ingredients: macrogol 6000, colloidal silicon anhydride (Aerosil R 972).

    No. UA/0054/04/01 dated 02.08.2004 to 02.08.2009

    caps. 400 mg, № 60 UAH 17.4

    Piracetam 400 mg

    No. UA/0054/05/01 from 04/01/2005 to 04/01/2010

    rr d / peroral. approx. 20% fl. 125 ml, No. 1

    Piracetam 20%

    No. UA/0054/02/01 from 07/08/2004 to 07/08/2009

    rr d / in. 20% amp. 5 ml, № 12 UAH 49.5

    rr d / in. 20% amp. 15 ml, No. 4 UAH 52.59

    Piracetam 200 mg/ml

    Other Ingredients: Sodium acetate, glacial acetic acid, water for injection.

    No. UA/0054/01/01 from 24.11.2003 to 24.11.2008

    rr inf. 20% fl. 60 ml, No. 1 UAH 59.94

    Piracetam 20%

    Dosage form

    solution

    Pharmacological properties

    nootropil (2-oxo-1-pyrrolidinacetamide) is a cyclic derivative of GABA. Piracetam is a nootropic that, through a direct effect on the brain, improves cognitive (cognitive) processes, such as learning ability, memory, attention, and also increases mental performance. Nootropil affects the central nervous system in various ways: by affecting the rate of spread of excitation in the brain, improving metabolic processes in nerve cells, improving microcirculation and hemorheology, without having a vasodilating effect. Piracetam inhibits platelet aggregation and restores the elasticity of erythrocyte membranes, reduces the adhesion of erythrocytes. At a dose of 9.6 g, it reduces the level of fibrinogen and von Willibrand factors by 30–40% and increases bleeding time. Piracetam has a protective and restorative effect in case of brain dysfunction due to hypoxia and intoxication, reduces the severity and duration of vestibular nystagmus.

    The maximum concentration of the drug after intravenous administration is reached in the blood after 30 minutes, and in the CSF after 5 hours, amounting to 40–60 μg / ml. The volume of distribution of piracetam is almost 0.6 l/kg. The half-life of the drug from blood plasma is 4-5 hours, and from the CSF - 8.5 hours. It does not bind to plasma proteins and is not metabolized in the body. 80-100% of piracetam is excreted by the kidneys unchanged through renal filtration. The renal clearance of piracetam in healthy volunteers is 86 ml/min. The pharmacokinetics of the drug does not change in patients with hepatic insufficiency.

    Piracetam penetrates the BBB, the hematoplacental barrier and membranes used in hemodialysis. In animal studies, piracetam selectively accumulated in the tissue of the cerebral cortex (mainly the frontal, parietal and occipital lobes), in the cerebellum and basal ganglia.

    Indications for use Nootropil

    symptomatic treatment of psycho-organic syndrome in elderly patients, accompanied by memory impairment, dizziness, reduced concentration and general activity, mood changes, behavioral disorders, gait disturbance, as well as in patients with Alzheimer's disease and senile dementia of the Alzheimer type.

    Treatment of the consequences of a stroke (chronic stage of ischemic stroke): speech disorders, emotional disorders, to increase motor and mental activity.

    Chronic alcoholism - for the treatment of psychoorganic and withdrawal syndromes.

    Coma (and during the period of convalescence), including after brain injuries and intoxications. Treatment of dizziness and related balance disorders, with the exception of dizziness of vasomotor and psychogenic origin.

    As part of the complex therapy of psychoorganic syndrome in children.

    Treatment of cortical myoclonus (as monotherapy or in combination with other drugs); in the complex treatment of sickle cell anemia.

    Contraindications

    hypersensitivity to piracetam or pyrrolidone derivatives, as well as to other components of the drug, hemorrhagic stroke, end-stage renal failure (creatinine clearance less than 20 ml / min), age up to 1 year

    Usage Precautions

    due to the effect of piracetam on platelet aggregation, it is recommended to use it with caution in patients with impaired hemostasis, during major surgical interventions or in patients with symptoms of severe bleeding. In the treatment of patients with cortical myoclonus, an abrupt interruption of treatment should be avoided, which may cause the resumption of attacks.

    With long-term therapy in elderly patients, regular monitoring of renal function is recommended, if necessary, the dose is adjusted depending on creatinine clearance.

    Given the possible side effects, the drug should be used with caution in patients working with potentially dangerous mechanisms and drivers of vehicles.

    Piracetam penetrates through the filtration membranes of hemodialysis machines.

    Animal studies have not revealed a negative effect of the drug on the embryo and its development, including in the postnatal period; piracetam did not affect the course of pregnancy and childbirth. There is no experience of using the drug during pregnancy. Piracetam crosses the hematoplacental barrier and into breast milk. The concentration of the drug in the blood of the fetus reaches 70-90% of that in the blood of his mother. During pregnancy, Nootropil is prescribed only if absolutely necessary. When prescribing the drug during lactation, it is advisable to refrain from breastfeeding.

    Interaction with drugs

    when combined with thyroid extract (TK + T4), only one case of increased irritability, disorientation and sleep disturbance was noted. There was no interaction with clonazepam, phenytoin, phenobarbital, valproic acid.

    Piracetam at a high dose (9.6 g/day) increased the effectiveness of acenocoumarol in patients with venous thrombosis: a significant decrease in the level of platelet aggregation, fibrinogen level, von Willebrand factor, blood and plasma viscosity was noted.

    The possibility of changing the pharmacodynamics of piracetam under the influence of other drugs is low, since 90% of the drug is excreted unchanged in the urine.

    Co-administration of 1.6 g of piracetam with alcohol does not affect the concentration of piracetam and alcohol in the blood serum.

    Method of application and dosage Nootropil

    the daily dose in adults is 30-160 mg / kg of body weight (the frequency of administration is 2-3 times a day). During meals or on an empty stomach. Nootropil is administered intramuscularly or intravenously, starting with 2–4 g and rapidly increasing the dose to 4–6 g/day. The duration of treatment and the individual dose depend on the severity of the patient's condition and the rate of reverse dynamics of the clinical picture of the disease. After improving the condition, they proceed to taking the drug inside.

    In the symptomatic treatment of chronic psychoorganic syndrome, depending on the severity of the symptoms, 1.2-2.4 g is prescribed, and during the first week - 4.8 g / day.

    In the treatment of perception disorders in brain injuries, the initial dose is 9–12 g / day, the maintenance dose is 2.4 g / day. The duration of treatment is at least 3 weeks.

    With alcohol withdrawal syndrome - 12 g / day. Maintenance dose - 2.4 g / day.

    Treatment of dizziness and related balance disorders - 2.4–4.8 g / day.

    For children over the age of 7 years, 3.6 g / day is prescribed to correct a reduced ability to learn. Treatment continues throughout the school year.

    With cortical myoclonus, the initial dose is 7.2 g / day, followed by an increase in dose by 4.8 g / day every 3-4 days until a maximum dose of 24 g / day is reached. Duration of treatment - during the entire period of the disease. Every 6 months it is necessary to reduce the dose, or cancel the drug to prevent an attack, gradually lowering the dose by 1.2 g every 2 days. If ineffective, the reception should be discontinued.

    In sickle cell anemia, the prophylactic daily dose is 160 mg/kg of body weight, divided into 4 equal parts. During the crisis - 300 mg/kg IV.

    Daily doses in children (if it is impossible to use oral forms of the drug) are: at the age of 1 to 3 years - 400 mg / day; from 3 to 7 years - 400-1000 mg / day; from 7 to 12 years - 400-2000 mg / day; from 12 to 16 years - 800-2400 mg / day.

    Patients with impaired liver function do not need dose adjustment.

    Side effects

    more often occur in elderly patients receiving piracetam at a dose of 2.4 g / day and above. In most cases, it is possible to achieve a regression of their severity with a decrease in the dose of the drug. In isolated cases, the following side effects have been reported:

    from the nervous system - dizziness, headache, ataxia, imbalance, exacerbation of epilepsy, insomnia;

    on the part of the psyche - agitation, anxiety, nervousness, hallucinations, increased sexual desire, rarely - drowsiness and depression;

    on the part of the skin - dermatitis, itching, rash, swelling.

    Overdose

    with oral administration of 75 g of piracetam, dyspeptic symptoms (diarrhea with blood, abdominal pain) were noted. No other symptoms of overdose were noted. After an overdose, the stomach should be washed. There is no specific antidote. Treatment is symptomatic, which may include hemodialysis. The effectiveness of hemodialysis is 50-60% of the dose of piracetam.

    Piracetam is the active ingredient of the drug.

    The tablets contain 800 or 1200 mg of this substance. Additional elements: macrogol 6000, silicon dioxide, croscarmellose sodium, magnesium stearate.

    Capsules of 400 mg of active ingredient. Additional substances: macrogol 6000, silicon dioxide, lactose monohydrate, magnesium stearate.

    The oral solution contains 1 ml of 200 or 330 mg of the active substance. Additional elements of the composition are: sodium saccharinate, pure water, , sodium acetate, acetic acid, methyl parahydroxybenzoate, fragrances, propyl parahydroxybenzoate.

    The solution of Nootropil in / in and / m contains 200 mg of the active substance per 1 ml. Auxiliary elements are: sodium acetate trihydrate, injection water, glacial acetic acid.

    Release form

    In tablets, capsules, as well as oral solution and solutions for intravenous and intramuscular use.

    pharmachologic effect

    Nootropic agent.

    Pharmacodynamics and pharmacokinetics

    The active substance is . The use of the drug Nootropil enhances the utilization of glucose, enhances the synthesis of phospholipids and RNA, increases the level of ATP in brain tissues, stimulates glycolytic reactions . The drug has a positive effect on brain tissues, facilitates the learning process, improves integrative work and brain activity, improves memory . Nootropil is able to suppress the aggregation of activated ones, does not have a vasodilating effect, but at the same time it has a positive effect on microcirculation and the speed of propagation of the excitation wave in the brain tissues. With brain damage on the background of intoxication, electric shock, the drug has a pronounced protective effect, reducing the severity of vestibular nystagmus, reduces delta activity and enhances alpha and beta activity by electroencephalogram . The drug improves cerebral blood flow, increases mental performance, improves conductivity between synapses in neocortical structures, and has a positive effect on interhemispheric connections. The therapeutic effect of the treatment develops gradually. The drug does not have psychostimulating and sedative effects.

    The drug is rapidly absorbed, not metabolized, does not bind to blood proteins. Excreted by the kidneys unchanged.

    Instructions for use of the drug Nootropil recommends prescribing the drug in neurology, narcology and psychiatry.

    AT neurological practice the medication is used for pathology of the nervous system, accompanied by disorders in the emotional-volitional sphere (for example,) and a decrease in intellectual-mnestic functions. The drug is prescribed after intoxication and traumatic brain injury, with chronic cerebrovascular insufficiency (, pronounced, speech, attention, memory disorders), with vascular pathology of brain tissues, with coma and subcoma, during the period of convalescence in order to increase mental and motor activity, with residual effects of cerebral circulatory disorders according to the ischemic variant.

    Indications for the use of Nootropil in psychiatry: sluggish defective conditions (such as psycho-organic syndrome, ), asthenodepressive syndrome (with a predominance of ideational retardation, with senesto-hypochondriac disorders, asthenic pathology, with adynamia), nephrotic syndrome . Piracetam is prescribed in the complex therapy of depressive states that are resistant to the effects of antidepressants, in the treatment of mental pathology that occurs on “organically defective soil”. The drug is recommended for prescription in case of intolerance to neuroleptics, antipsychotic drugs in order to eliminate mental, neurological and somatovegetative complications. The drug is prescribed for cortical form of myoclonus.

    Nootropil in narcological practice used for cupping alcohol withdrawal syndrome , in acute poisoning , barbiturates , morphine, ethanol, with morphine withdrawal syndrome, chronic (in combination with intellectual-mnestic disorders, asthenia, persistent pathology of the psyche). The drug can be used as part of combination therapy in the treatment sickle cell anemia .

    In order to eliminate the consequences of perinatal damage to brain structures, to improve the learning process, with children's cerebral , mental retardation Nootropil can be used in pediatrics.

    Contraindications

    The drug is not used for hemorrhagic , with severe pathology of the renal system, with intolerance to the main substance piracetam. When carrying, heavy bleeding , after extensive surgical interventions, with pathology hemostasis and when Nootropil is prescribed with caution, assessing the possible risks.

    Side effects

    There are the following side effects during treatment: vomiting, nausea, impaired concentration, imbalance, motor disinhibition, mental arousal , gastralgia, sleep disorders, anxiety, appetite disorders, stool disorders, increased sexual activity, convulsive syndrome , extrapyramidal disorders, headache, dizziness, . When diagnosed, there is a worsening of the course of the disease. Most often, side effects are recorded when the recommended dose of 5 g per day is exceeded.

    Instructions for use Nootropil (Method and dosage)

    The drug is prescribed intravenously, intramuscularly and orally.

    Instructions for the solution

    The initial dosage of the drug for parenteral intravenous administration is 10 g. In severe pathology, the drug is administered intravenously in drops up to 12 g per day, the duration of the infusion is 20-30 minutes. Upon reaching a therapeutic effect, the amount of the drug is reduced with a gradual transition to oral administration.

    Tablets Nootropil, instructions for use

    The drug is taken twice a day, the daily dosage is 30-160 mg per 1 kg. It is possible to increase the frequency of administration up to 3-4 times a day if necessary. The course of treatment according to this scheme is up to 2-6 months.

    At treatment of memory disorders, cognitive disorders the drug is prescribed orally at the initial stages of therapy three times a day for 1600 mg, in the future, the amount of the drug is reduced to 800 mg.

    Treatment cerebrovascular disease in the acute stage, it is necessary to start as soon as possible with a dose of 12 g per day for two weeks, then switch to a dosage of 6 g per day.

    Therapy cortical myoclonus start with 7.2 g per day with a gradual increase in the amount of active substance by 4.8 g per day every 3-4 days. The maximum dose is 24 grams in 24 hours.

    Daily dosage at sickle cell anemia is 160 mg per 1 kg (4 doses). In the crisis period, the dose is increased to 300 mg per 1 kg.

    In case of violations of the kidneys, the drug is used with caution. The dose is prescribed by the doctor.

    How to take a drug to improve memory?

    It is necessary to take the medicine 2 times a day. The following dosage is advised to improve memory - 8 ml of a 20% oral solution.

    Overdose

    Possible bloody diarrhea or abdominal pain at doses greater than 75 g per 24 hours. Treatment is as follows: gastric lavage or induction of vomiting, hemodialysis can be used.

    Interaction

    Nootropil reduces the risk of developing extrapyramidal disorders with simultaneous therapy with neuroleptics. The description of the drug Nootropil indicates its ability to increase efficiency indirect anticoagulants , antipsychotic drugs, psychostimulant drugs and thyroid gland .

    Terms of sale

    Presentation of a medical prescription is required.

    Storage conditions

    In a dry place inaccessible to children at a temperature not exceeding 25 degrees Celsius.

    Best before date

    Not more than 4 years.

    special instructions

    Treatment with Nootropil requires regular monitoring of the work of the renal, hepatic systems, the condition peripheral blood , level and residual nitrogen. Drug therapy can be combined with psychoactive drugs, drugs for the treatment of cardiovascular diseases. Treatment of acute lesions of tissues and structures of the brain is recommended to be carried out in combination with the methods of restorative medicine, detoxification therapy . In psychiatric diseases, psychoactive drugs are simultaneously prescribed. Abrupt withdrawal of the drug is unacceptable, especially in the treatment of patients suffering from the cortical form. myoclonus (because of the high risk of recurrence of seizures and seizures). With the development of such side effects as or excessive drowsiness, it is recommended to stop taking the medication in the evening. When Nootropil penetrates through special filtering membranes in the apparatus. Piracetam affects the ability to drive a vehicle.

    The drug is not described in Wikipedia.

    Alcohol compatibility

    Alcohol does not affect the content of piracetam in serum, in turn, when taking 1.6 g of the active substance, the level of alcohol in the blood also did not change.

    Nootropil's analogs

    Coincidence in the ATX code of the 4th level:

    Analogues are drugs: Biotropil , .

    The price of Nootropil analogues is lower and higher. For example, Piracetam costs less.

    Which is better: Nootropil or Piracetam?

    Medicines are generics, that is, they contain one active substance, piracetam, and have a similar effect on the body. The drug Piracetam is of domestic production, and therefore it is cheaper, however, it is also considered to be less purified.

    Nootropil tablets are a remedy that improves cerebral circulation, stimulates nervous activity and enhances the regeneration of brain tissue. The drug is based on piracetam. This chemical has been used by neurologists for several decades. During this period, all side effects were thoroughly studied and measures were taken to neutralize them. In this regard, the drug nootropil can be absolutely safely used from the earliest childhood in the complex treatment of various diseases of a cerebral nature.

    The pharmacological industry produces nootropil for use in various dosage forms. It is a granular powder that can be used to prepare syrup for children, ready-made syrup, capsules for oral use and solution in ampoules for intravenous and intramuscular administration.

    It should be borne in mind that nootropil tablets can be used to treat brain diseases only in adults. For children, the drug is given as a syrup or as an injection as prescribed by a doctor.

    Therapeutic action

    The pharmacological effect on brain structures is based on the effect of the drug on metabolic processes in the nervous tissue. 72 hours after the initial administration of the active substance, the processes of accumulation of adenosine triphosphoric acid in the main tissues of neurons are activated. Against this background, RNA production increases and a large number of phospholipids of prolonged action appear. Glycolytic metabolic processes are stimulated due to the increased synthesis and utilization of decomposition products of carbohydrate inclusions.

    In the process of using nootropil, the following is achieved:

    • strengthening of integrative processes between neurons;
    • increase in the productivity of the brain;
    • improving the processes of memorization and perseverance;
    • acceleration of the educational process;
    • improving the overall level of performance.

    After entering the brain tissue, the drug begins to quickly have a positive effect on the processes of blood microcirculation. The lumen of the blood vessels remains unchanged, which ensures reliable prevention of hemorrhagic strokes. Against the background of prolonged treatment, reduced platelet aggregation is observed, which has a beneficial effect on the viscosity and other rheological properties of the blood.

    Due to the protective effect on the brain, this drug can be prescribed for prolonged exposure to various toxins, including alcohol, on the human body. A positive effect is observed after an injury, an electric shock, against the background of prolonged oxygen starvation. With a concussion of the brain, nootropil contributes to the rapid elimination of ataxia, dizziness, manifestations of vestibular nystagmus.

    During treatment, you should be aware that positive therapeutic results do not appear from the first day of course therapy. The first signs of a positive effect can be seen after 7 - 10 days from the start of treatment. At the same time, patients do not experience inhibition or stimulation of nervous and mental activity. For the period of treatment with nootropil, in the absence of other pronounced symptoms that impede normal work activity, restrictions on the spheres of work and its intensity are not required.

    Indications

    The drug nootropil instructions for use recommends using in narcological and psychiatric, pediatric and neurological practice. The greatest effectiveness of the drug is observed in complex therapy in combination with other pharmacological preparations of the following diseases:

    • damage to cerebral vessels;
    • atherosclerosis;
    • cerebral vascular insufficiency of uncertain origin, which is accompanied by disturbances in the process of memorization, headaches and dizziness, decreased brain activity;
    • trauma to brain structures;
    • damage by alcohol, nicotine, certain drugs;
    • consequences of the transferred violation of cerebral circulation according to the ischemic type;
    • Alzheimer's disease and other forms of encephalopathy.
    • In psychiatry, there are also separate indications for the use of nootropil:
    • asthenia with elements of depression;
    • hypochondria with adynamic syndrome;
    • mental retardation with damage to the psyche;
    • various forms of myoclonus.

    In adolescence, the drug improves the processes of social adaptation, reduces the level of psychological tension, shyness and a tendency to depressive states. At an early age, nootropil is indicated for children with birth injuries and intrauterine damage to brain structures, including cerebral palsy. The drug helps to cope with the consequences of intrauterine fetal hypoxia, excluding the further development of the destruction of the nervous tissue.

    In narcological practice, the drug can effectively eliminate the consequences of the use of alcoholic and narcotic substances. During the withdrawal period, negative side effects are removed, and the process of complete restoration of the affected brain structures is achieved. During the period of treatment for alcoholism and drug addiction, nootropil can reduce the painful psychological craving for the use of toxic substances. Improves the psychological state of a sick person.

    How to take nootropil?

    Severe conditions at the initial stage of treatment The drug is administered intravenously slowly at a dose of at least 10 grams per day
    Treatment of moderate conditions 600 mg 3 times a day for 60 days
    Senile dementia and organic lesions of brain structures Long-term 600 mg 3-4 times a day
    Nootropil for children In the form of syrup, not more than 50 mg per day
    brain injury 400 mg 3 times a day for 15 days

    The drug should be taken in the morning. After 5 p.m., taking nootropil is not desirable, as this can provoke a disruption in the process of falling asleep. Also, when taken in the evening, cases of increased blood pressure are not uncommon. Direct analogue of nootropil -

    Similar posts