nicotinic acid solution. Nicotinic acid instructions for use

Registration number: Р№ 000944/02

Tradename: A nicotinic acid

International non-proprietary name: A nicotinic acid

chemical name: 3-pyridinecarboxylic acid

Dosage form: tablets

Compound
1 tablet contains:
Active ingredients: 0.05 g of nicotinic acid.
Excipients: glucose, stearic acid.

Description. White tablets.

Pharmacotherapeutic group. Means regulating metabolic processes. Vitamin preparation.

ATX code: [S10AD02].

Pharmacological properties.
Nicotinic acid is a specific antipelargic agent (vitamin PP). It improves carbohydrate metabolism, has a vasodilating effect, including on the vessels of the brain, and has lipid-lowering activity. In large doses of 3-4 g per day, nicotinic acid reduces the content of triglycerides and low-density lipoproteins in the blood, reduces the ratio of cholesterol / phospholipids in low-density lipoproteins. Has detoxifying properties.

Indications for use:
Prevention and treatment of pellagra (avitaminosis PP); complex therapy of ischemic disorders of cerebral circulation, obliterating diseases of the vessels of the extremities (obliterating endarteritis, Raynaud's disease) and kidneys, complications of diabetes mellitus (diabetic polyneuropathy, microangiopathy); liver diseases (acute and chronic hepatitis), gastritis with low acidity, neuritis of the facial nerve, various intoxications (professional, drug, alcohol), long-term non-healing wounds and ulcers.

Contraindications:
Hypersensitivity to the drug. Peptic ulcer of the stomach and duodenum (in the acute stage); severe arterial hypertension; gout; hyperuricemia, nephrolithiasis, liver cirrhosis, decompensated diabetes mellitus.
Pregnancy and the period of breastfeeding.

special instructions
To prevent complications from the liver (with prolonged use in high doses), it is recommended to include foods rich in methionine (cottage cheese) in the diet or use methionine, lipoic acid, essentiale and other lipotropic agents. Caution should be used for gastritis with high acidity, gastric ulcer and duodenal ulcer (history). During treatment with nicotinic acid (especially large doses), liver function should be carefully monitored.

Dosage and administration
Used as directed by a doctor.
Nicotinic acid tablets are taken orally after meals. As an antipelargic agent, nicotinic acid is prescribed for adults at a dose of 0.1 g 2-4 times a day (the highest daily dose is 0.5 g). Children are prescribed from 0.0125 to 0.05 g 2-3 times a day, depending on age. The course of treatment is 15-20 days.
For adults with ischemic disorders of cerebral circulation, spasms of the vessels of the extremities, gastritis with low acidity, neuritis of the facial nerve, wounds and ulcers, it is recommended to prescribe nicotinic acid in a single dose of 0.05-0.1 g, in a daily dose - up to 0.5 g. treatment - 1 month.

Side effect
Allergic reactions, dizziness, reddening of the face, a feeling of a rush to the head, paresthesia are possible. In this case, the dose should be reduced or the drug discontinued. With prolonged use of large doses of nicotinic acid, it is possible to develop fatty degeneration of the liver, hyperuricemia, increased activity of hepatic transaminases and alkaline phosphatase, and a decrease in glucose tolerance.

Interaction with other drugs
Consultation with a doctor is necessary if nicotinic acid is to be used simultaneously with other drugs.

Release form
50 tablets in dark glass jars. 10 tablets in a blister pack. Each jar or 5 blister packs is placed in a cardboard box.

Best before date
4 years. Do not use the drug after the expiration date.

Storage conditions
List B. Store at room temperature, in a dry, dark place. Keep out of the reach of children.

Vacation from pharmacies
Without recipe.

Manufacturer: JSC "VEROPHARM"
Legal address: 107023, Moscow, Barabanny per., 3.
Address of production and acceptance of claims: 308013, Belgorod, st. Working, d. 14.

Vitamin B3 / PP, which is called niacin due to the large number of forms, nicotinamide is used in the medical and cosmetic industries. The beneficial properties of the vitamin are so unique that it is equated to a drug. The international name of the substance is nicotinic acid (in Latin "Acidum nicotinicum").

History of the discovery of niacin. Mankind had to survive in the conditions of the development of new diseases. The vitamin formula was discovered in the nineteenth century to combat the severe disease pellagra. This terrible disease developed in people due to an insufficient standard of living, accompanied by hallucinations, depression, nausea, vomiting and diarrhea. Soon pellagra was found in people who abuse alcohol. The literal translation of B3 / PP vitamins is warning pellagra.

Why does the body need niacin? The main function of vitamin PP is participation in the course of redox processes. Due to the effect of the substance, the growth of body tissues is normalized, the metabolism of fat cells improves, the amount decreases, sugar and fats are processed into positive energy.

Why is niacin prescribed? Vitamin PP protects the body from the most complex diseases: platelets, diabetes, hypertension, etc. Nicotinic acid is used to treat disorders of the functionality of the nervous system, to combat migraines.

With a sufficient amount of vitamin PP in the human body, the gastrointestinal tract works without failures and pathological abnormalities. When inflammation occurs, the body fights the process, it is easier to digest the incoming food, and it produces gastric juice better. B3 / PP has a positive effect on the functioning of the pancreas and liver. Vitamin occupies a leading place in the synthesis of hemoglobin, the production of red blood cells, in the ratio of hormones. Better than the substance that regulates the level of cholesterol in the blood, you will not find.

Vitamin PP helps the body produce the right amount of energy, increases blood sugar during a catastrophic drop in its level, which helps fight diabetes and hypertension. The substance is prescribed to increase metabolism, and reduce the amount of triglycerides. In addition, niacin affects the protective properties of the pancreas, so problems with insulin do not threaten everyone who uses nicotinic acid.

Vitamin PP should be used for problems with the nervous system, in cases of loss of concentration, manifestations of a depressive state. Thanks to the preventive use of the drug, it is possible to avoid the development of schizophrenia and other mental disorders.

Signs of excess and deficiency of niacin in the body

For an adult to maintain a normal level of vitamin B3, it is recommended to consume 20 mg of the substance per day. For children, the norm is set from 6 mg, depending on age. Doctors say that, unlike girls, adolescent boys need an increased amount of nicotinic acid.

Women during pregnancy and lactation, performing athletes, use vitamin PP in the amount of 25 mg per day.

Depending on the diet, the use of nutritional supplements, both a deficiency and an overdose of a substance occur in the body. The reaction to the drug remotely resembles an allergy, so the benefits and harms of "nicotine" are regularly discussed on forums and chats.

Symptoms of an excess of vitamin B3 / PP:

• disorders of the digestive tract;
• lack of appetite;
• nausea;
• weakness;
• diarrhea;
• muscle pain;
• sleep disorders;
• hallucinations.

The lack of vitamin B3 / PP in the body is manifested by the deterioration of the body:

• skin problems (redness, rashes, peeling, dermatitis, etc.);
• tachycardia;
• low blood sugar;
• pain in the upper and lower extremities;
• weakness.

To replenish the supply of nicotinic acid, add foods with a high content of the substance to your usual diet. Despite cooking (frying, drying, canning), 90% of the vitamin remains intact. Read more about the group of foods with high levels of niacin below.

An overdose of vitamin PP does not pose a danger to human health. Testing has shown that negative symptoms in the form of dizziness, redness of the skin in the head area, and numbness appear only after taking the vitamin on an empty stomach.

For medicinal purposes, nicotinic acid is administered intravenously, in which case blood pressure drops sharply. Do not be afraid of this symptom, because after a while the processes will normalize, the side effects will disappear.

You should not use nicotinic acid on your own, since it is a drug, the appointment of which is controlled by a specialized physician.

With prolonged use of the drug, the following symptoms are possible:

• loss of appetite;
• headache constantly;
• change in the color of urine;
• the skin becomes yellowish;
• liver dystrophy develops.

To avoid such negative consequences, you should responsibly approach the use of the drug. Doctors recommend taking methionine and lipotropic drugs in parallel with nicotinamide. An increased amount of methionine is found in the following products:

• cottage cheese;
• meat;
• fish;
• eggs;

Nicotinic acid is a harmless vitamin, but not everyone can use it. Contraindications regarding the intake of vitamin PP are clearly spelled out in the instructions for use: liver disease, stomach and duodenal ulcers, gout, chronic forms of hypertension and atherosclerosis.

This is not all that vitamin B3 is useful for.

Most people do not even know what products contain nicotinic acid. The advantage in terms of the amount of vitamin PP in products of animal origin:

• lean pork;
• liver;
• chicken breast;
• low-fat varieties of fish;
• kidneys;
• chicken eggs;
• dairy.

Getting a vitamin is possible from a plant food group:

• tomatoes;
• potato;
• carrot;
• peanut;
• yeast, etc.

Medicinal plants are rich in vitamin PP, most of all:

• alfalfa;
• sage;
• sorrel;
• rose hip;
• burdock root;
• eyebright;
• dandelion, etc.

Niacin is present in all food groups, but absorption rates vary. What is the difference? Vitamins of legumes are easily absorbed by the body, while grains are difficult to digest. The synthesis of nicotinic acid occurs exclusively in the presence of the amino acid tryptophan, which is replenished in the body when proteins of animal origin are consumed.

Studies have proven that the quantitative determination of vitamin PP in food products is determined by chemical, spectrophotometric and microbiological methods.

Nicotinic acid in drugs

The properties of vitamin B3 have led to its popularity in the pharmaceutical industry. The release form of nicotinic acid has three variations:

1. Ampoules. The solution is being developed for intramuscular injection of the drug. Injections are attributed to patients with gastrointestinal diseases. The advantage of this form is the immediate entry of the substance through the bloodstream into the cells where biochemical reactions occur.
2. Capsules. They are prescribed for hypovitaminosis, since it is not always possible to replenish the necessary supply of vitamin with food. The medicine corrects this deficiency a week after the start of the reception.
3. Tablets. They have the same purpose as the capsule, they are prescribed to eliminate the lack of niacin.

Storage of vitamin PP: the sealed preparation is stored in a dry place where the sun's rays do not fall. The shelf life of ampoules is four years, and tablets - three. Before using the substance, examine the date of its manufacture and the integrity of the package. The authenticity of the drug is confirmed by multi-stage laboratory tests.

Due to the peculiarities of the chemical structure, niacin (chemical formula C6H5NO2) is actively used in traditional medicine. Vitamin PP penetrates deeply into the cells of the body, so the spectrum of application of the vitamin is extremely wide.

Indications for the appointment of nicotinic acid is used:

• with violations of the gastrointestinal tract updates;
• with a hernia of the spine;
• in violation of the brain (memory impairment, inattention, absent-mindedness);
• in a depressed state;
• with angina;
• with diabetes mellitus of the acquired type;
• with alopecia;
• with osteoarthritis;
• with cardiovascular diseases;
• during menstruation;
• with multiple sclerosis;
• with beriberi (lack of vitamin B3 / PP leads to a decrease in immunity);
• with osteochondrosis, in particular with cervical osteochondrosis;
• with pellagra. This disease occurs due to a deficiency of vitamin PP in the human body due to malnutrition. Pellagra manifests itself in people suffering from alcoholism, chronic diseases of the gastrointestinal tract, but it often occurs in pregnant women;
• with violations of the functionality of the small intestine;
• with pathological abnormalities in the work of the liver, gallbladder, thyroid gland;
• with gastritis;
• with dysbacteriosis;
• with anorexia;
• with hereditary pathologies;
• with hypertension;
• with malignant tumors;
• during pregnancy and lactation;
• with a headache.

Nicotinic acid will not become superfluous for people who use alcohol, oral contraceptives, for smokers it is completely irreplaceable. For children, vitamin B3 / PP is prescribed exclusively by a pediatrician if there is an urgent need.

Niacin helps fight secondary symptoms of diseases. The drug is used for numbness of the fingers. To do this, you need to turn to intramuscular injections, they will also save you from chondrosis when used together with vitamin B and prozerin.

For prevention, vitamin PP should be taken in tablets; in the treatment of diseases, it is better to use the liquid form of the drug. The treatment regimen and dosage of the drug are prescribed after clinical studies and the patient's history.

Vitamin b3/PP is regularly used in cosmetology. With the help of drugs, you can improve your health, improve your skin, hair condition. We offer to consider the popular applications of niacin.

For face

Nicotinic acid is the main element in the nutritional and regenerative process of cells. In addition to a beneficial effect on the functionality of organs, niacin becomes a reliable assistant in the fight for the beauty and health of the skin, so it is often used for rejuvenation.

With an insufficient amount of a substance in the body, the first signs appear on the skin: red spots, itching, decreased elasticity. As soon as you notice such problems in yourself, consume as many products containing nicotinic acid as possible and apply the vitamin externally. With an integrated approach, there will be no trace of acne.

Rating world companies in facial skin care cosmetics use 4% nicotinic acid. Vitamin is freely available in every pharmacy, so you can add it to your favorite creams yourself.

The effect of nicotinic acid for the beauty of facial skin:

• dilates blood vessels;
• improves blood circulation;
• removes excess fluid from tissues;
• has an anti-inflammatory effect;
• retains moisture necessary for tissues;
• promotes regeneration;
• cleanses the skin and improves its color.

In clinical conditions, scientists have discovered another useful property - nicotinic acid minimizes the formation of skin cancer.

Skin cancer is less common in people who take advantage of the properties of niacin. Reviews on how to use vitamin B3 to improve the condition of the face can be read on women's forums.

face mask recipe

In the usual lotion, cream, an ampoule of nicotinic acid is added (1 ampoule per 50 g of face product). A vitamin remedy is applied as a standard cream, if necessary, washed off with warm. It is advisable to mix the drug in a separate container of small volume, since prolonged use of the vitamin leads to an overdose.

For hair growth

Nicotinic acid is considered a reliable remedy for accelerating hair growth. We warn you that even minimal contact with the substance on the skin provokes an allergic reaction. Allergies in the form of redness, slight turbidity will disappear after 20 minutes, leaving no traces of themselves. The drug should be used with caution on its own.

Sometimes people are skeptical about the properties of nicotinic acid because of the repulsive name. The substance is not associated with smokers, forget about prejudice. Nicotine and nicotinic acid are not the same thing.

Niacin, due to its availability, has become popular for home use. Women prepare healing masks, shampoos and scrubs on its basis. A couple of drops of nicotinic acid are added to your favorite shampoo and during each wash your hair is fed with vitamins.

The drug affects the scalp, as there is a strengthening of blood vessels. Nicotinamide gets on the scalp and instantly penetrates into the inner layer of the epidermis. With improved blood flow, vitamin PP enters the bulb of each hair. Changes in the condition of the hair can be observed after five procedures. Folk remedies, despite the action, at first dry out the hair or enrich it with an unpleasant odor. When hair falls out, a person is ready to endure all the consequences, with “nicotine” you can not be afraid for such negative accompanying factors.

Vitamin PP is involved in the oxidative processes of the body, so the hair has a complex effect. Hair follicles are fed with vitamin, saturated with oxygen. The main advantage of hair care with nicotinic acid is moisturizing along their length. Dandruff disappears under the influence of a nourishing vitamin.

If you are wary of additives that are not provided by the manufacturer, drink nicotinic acid in tablets. Thus, you influence the growth of hair, strengthen the condition of the body.

Nicotinic acid is considered a popular drug for hair loss and baldness. Rapid hair loss is the main signal of a malfunction in the body, so first of all, go through a doctor's examination, and in no case start treatment without an appointment.

To stop hair loss, nicotinic acid is rubbed into the scalp on dry hair. Additional ingredients can improve the effect of the drug, with which the vitamin formula is combined:

• decoction of medicinal herbs;
• propolis tincture;
• ginger;
• vitamin E.

Compatibility of drugs contributes to the achievement of quick results in a short time. The course of treatment lasts for one month, only after consultation with a trichologist. The composition of the product for one rubbing uses only one ampoule of nicotinic acid. The vitamin is applied from the side of the temporal region, with massage movements go to the top of the head. Before the procedure, draw liquid into a syringe or pipette, so it is more comfortable to apply the vitamin in even portions to the scalp.

It is necessary to use acid in ampoules immediately after opening, otherwise, under the influence of air, it loses its beneficial properties and becomes unsuitable for further use.

Carefully monitor the body's reaction to vitamin PP in its pure form, if after the procedure the skin turns red, itching appears, drink an anti-allergenic drug, then dilute the acid with purified water.

Recipes for hair masks based on nicotinic acid (analogues of expensive cosmetic products):

Egg mask.

For its manufacture you will need:

• 1 ampoule of niacin;
• 1 capsule of vitamin E;
• linseed oil - 40 g;
• Eleutherococcus tincture - 20 g.

How to use: Mix the ingredients and apply to washed, dried hair. After an hour, wash off the mask and wash your hair under running water.

Nicotinic acid displaces vitamin C from the body, so you should additionally take ascorbic acid in the form of pharmacological vitamins. How much to take a vitamin complex depends on the state of the body and the obvious symptoms.

Niacin is an excellent remedy for cellulite. There is a lot of information on the Internet about how to take a vitamin. To some extent, the recommendations have a basis for existence, since the substance improves blood circulation. Due to contraindications in the instructions for vitamin B3, it is better to refuse to use it unnecessarily. Other ways to get rid of cellulite at home: can massage, body wraps, contrast showers.

Carefully monitor the dosages of vitamin PP to avoid overdose. Before drinking nicotinic acid, consult a doctor and carefully read the instructions for use, pay attention to contraindications.

In gynecology, nicotinic acid is used to eliminate premenstrual syndrome, to combat spasm and severe bleeding. Vitamin B3 / PP has a positive effect on the body, but it is still not clear whether women can take nicotinic acid during pregnancy.

Instructions for use for the drug clearly states that the vitamin is not consumed during pregnancy and lactation. Pregnancy does not always go smoothly, so you can not do without the additional use of niacin.

Nicotinic acid is prescribed to pregnant women and nursing mothers in the following cases: multiple pregnancy;

• pathological processes in the liver, provoked by pregnancy;
• mother's dependence on nicotine and certain drugs;
• abnormal functioning of the placenta.

It is strictly forbidden to take vitamin PP on your own during pregnancy without a doctor's prescription. An overdose may adversely affect the development of the fetus. When breastfeeding, you can take a vitamin only if it is not contraindicated for the baby.

With the controlled use of nicotinic acid, the expectant mother reduces spasms, improves blood circulation. With oxygen starvation of the fetus, niacin improves the metabolic process and eliminates placental insufficiency. In severe cases, vitamin PP for pregnant women will help maintain pregnancy and give birth to a healthy baby. An antihypoxant in small doses will provide the fetus with the right amount of oxygen.

During pregnancy, nicotinic acid is prescribed to thin the blood to avoid blood clots. In this case, vitamin B3 acts as a prevention of premature birth and possible complications.

A deficiency of nicotinic acid in the body of a future mother is manifested not only by hair loss, dry skin, but also negatively affects the psycho-emotional state of a woman. Scientific data on the change in the mood of pregnant women from a cheerful laughter to a depressive maiden confirmed that the lack of vitamin PP is to blame for everything.

Niacin in professional sports

In small doses, nicotinic acid acts as a maintenance supplement, and in excessive amounts it has a serious pharmacological effect. Why do athletes need "nicotine"? Intravenous administration of 10 mg of niacin doubles the amount of growth hormone in the blood. Growth hormone stimulates the growth of muscle mass and activates fat burning processes. In bodybuilding, professional athletes increase the dose of vitamin PP to 250 mg. The final dosage depends on the height, weight and age of the athlete. The table with numbers is freely available.

Among professional athletes, unspoken rules have been developed on how to take vitamin B3 / PP:

• before intense cardio or strength training;
• before intense fat burning training.

In other cases, taking nicotinic acid does not make sense. During the drying period, niacin is simply indispensable, but do not overdo it. How to use nicotinic acid in sports should be discussed with the doctor and trainer. Allergic reactions from an overdose lead to undesirable consequences before the day of the performance. For athletes, not only the regime, proper nutrition, training, but also the right vitamin complex is important.

Nicotinic acid is an affordable remedy that will help prevent the development of serious diseases. Positive reviews confirm the positive effect of the vitamin on the condition of the skin, hair and body as a whole.

pharmachologic effect

Vitamin and lipid-lowering agent. In the body, nicotinic acid is converted into nicotinamide, which binds to coenzymes of codehydrogenase I and II (NAD and NADP) that carry hydrogen, participates in the metabolism of fats, proteins, amino acids, purines, tissue respiration, glycogenolysis, and synthetic processes. Compensates for the deficiency of PP (vitamin B 3), is a specific anti-pellagric agent (avitaminosis of vitamin PP). Normalizes the concentration of blood lipoproteins; in high doses (orally 3-4 g / day) reduces the concentration of total cholesterol, LDL, TG, reduces the cholesterol / phospholipids index, increases the content of HDL, which have an antiatherogenic effect. It has a vasodilating effect at the level of small vessels (including the brain), improves microcirculation, has a weak anticoagulant effect (increases the fibrinolytic activity of the blood).

The hypocholesterolemic effect is noted after a few days, the decrease in TG - a few hours after administration.

Indications

Hypo- and avitaminosis PP: pellagra, inadequate and unbalanced nutrition (including parenteral), malabsorption syndrome (including against the background of pancreatic dysfunction), rapid weight loss, gastrectomy, Hartnup's disease (a hereditary disease accompanied by impaired assimilation of some amino acids, including tryptophan), gastrointestinal diseases (gluten enteropathy, persistent diarrhea, tropical sprue,).

Conditions of increased body need for vitamin PP: prolonged fever, diseases of the hepatobiliary region (acute and chronic hepatitis, cirrhosis of the liver), hyperthyroidism, chronic infections, malignant tumors, prolonged stress, pregnancy (especially against the background of nicotine and drug addiction, multiple pregnancy), period lactation.

Hyperlipidemia, incl. primary hyperlipidemia (types IIa, IIb, III, IV, V).

Ischemic disorders of cerebral circulation, obliterating diseases of the vessels of the extremities (obliterating endarteritis, Raynaud's disease), spasm of the vessels of the extremities, bile and urinary tract; diabetic polyneuropathy, microangiopathy.

Neuritis of the facial nerve, hypoacid gastritis, enterocolitis, colitis, non-healing wounds and trophic ulcers.

Contraindications

Hypersensitivity to nicotinic acid.

For oral administration: peptic ulcer of the stomach and duodenum in the acute phase, children under 2 years of age (as a lipid-lowering agent).

For parenteral use: severe arterial hypertension, atherosclerosis, gout, hyperuricemia, childhood.

Dosage

For the prevention of pellagra, adults inside 15-25 mg / day, children - 5-20 mg / day. With pellagra, adults inside 100 mg 2-4 times / day for 15-20 days, parenterally - 10 mg 1-2 times / day for 10-15 days. Children inside - 5-50 mg 2-3 times / day. For other indications, inside adults 20-50 mg (up to 100 mg), children - 5-30 mg 2-3 times / day. In ischemic stroke, 10 mg is administered intravenously.

Side effects

From the side of the cardiovascular system: flushing of the skin of the face and upper half of the body with a tingling and burning sensation, with rapid administration - a decrease in blood pressure, orthostatic hypotension, collapse.

From the side of the central nervous system and peripheral nervous system: paresthesia, dizziness.

From the digestive system: with prolonged use - fatty degeneration of the liver.

From the side of metabolism: with prolonged use - hyperuricemia, decreased tolerance to, increased blood levels of AST, LDH, alkaline phosphatase.

Local reactions: soreness at the site of s / c and / m injections.

Others: allergic reactions.

drug interaction

Care must be taken when combined with antihypertensive drugs, anticoagulants and.

Nicotinic acid reduces the toxicity of neomycin and prevents the decrease in the concentration of cholesterol and HDL induced by it.

special instructions

Use with caution orally in patients with hemorrhages, glaucoma, gout, hyperuricemia, liver failure, arterial hypotension, hyperacid gastritis, gastric ulcer and duodenal ulcer (in remission).

Use with caution parenterally in patients with hemorrhages, glaucoma, liver failure, arterial hypotension, hyperacid gastritis, peptic ulcer of the stomach and duodenum (in the acute phase).

During treatment, it is necessary to monitor liver function.

It is not advisable to use for the correction of dyslipidemia in patients with diabetes mellitus.

To prevent complications from the liver, it is recommended to include foods rich in methionine (cottage cheese) in the diet or use methionine and other lipotropic agents.

Application in childhood

Contraindications:

- for oral administration: children under 2 years of age (as a lipid-lowering agent).

- for parenteral use: children's age.

For impaired liver function

Use with caution in patients with hepatic impairment.

With prolonged use of nicotinic acid in high doses, the development of fatty infiltration of the liver is possible.

During treatment, it is necessary to monitor liver function. To prevent complications from the liver, it is recommended to include rich foods (cottage cheese) in the diet or use methionine, lipoic acid and other lipotropic agents.

Nicotinic acid or niacin is a water-soluble vitamin PP or B3, which is necessary to ensure redox reactions in the organs and tissues of the human body. Under natural conditions, vitamin PP is found in a large number of foods. animal origin: liver, eggs, seafood, chicken meat, pork, as well as vegetables and cereals.

Nicotine normalizes metabolic processes, participates in the restoration of nerve fibers, provides lipid and carbohydrate metabolism.

The lack of a substance affects the blood supply, the condition of the blood vessels, affects the timely removal of toxins and ethyl alcohol from the body.

If niacin is deficient, a person is more likely to diseases dermatitis, pelagra and diarrhea.

Composition and form of release of the drug

Vitamin PP is produced in two dosage forms that have the same therapeutic effect. These are tablets and solution for injections. In this regard, they are usually united by a common name - "Nicotinic acid preparations"

pharmachologic effect

Nicotinic acid is the only vitamin that has therapeutic action and is used to treat a number of diseases. Also. This remedy is actively used to lower cholesterol levels.

It affects the production of enzymes that carry out carbohydrate metabolism in the body.

Its action normalizes the production of insulin, estrogen, testosterone and progesterone in the human body.

Nicotinic acid has vasodilating action, improves blood circulation in small blood vessels, reduces the risk of blood clots. Regular use of nicotinic acid reduces the risk of developing type 1 diabetes, myocardial infarction and other pathologies of the cardiovascular system.

The drug reduces pain in osteoarthritis, has a positive effect on joint mobility.

The drug has sedative properties, therefore it serves as a remedy for the treatment of depressive conditions, increased anxiety, distracted attention.

The drug is used to detoxify the body after exposure to toxic substances and alcohol.

Nicotinic acid indications for use

The use of nicotinic acid preparations is indicated for patients with the following diseases and pathological states:

Contraindications

It is not recommended to use the drug in case of hypersensitivity to the active substance, as well as in the case of gastric ulcer and duodenal ulcer, liver cirrhosis, excess uric acid in the blood, atherosclerosis, changes in blood sugar levels in patients with diabetes mellitus.

Nicotine can be used for treatment only as directed specialist with low blood pressure, hemorrhages, glaucoma.

Instructions for use

The use of nicotinic acid is possible only on prescription. The action of the drug will be most effective if the state of the body is associated with a deficiency of this substance.

Treatment with the use of nicotinic acid is carried out according to the scheme prescribed by the doctor. A single use of the drug does not give any result.

The use of the drug is possible in the form of intravenous, intramuscular and subcutaneous injections. intravenous the introduction of the drug is carried out in a hospital by a medical officer. The drug is administered slowly, in a stream.

Subcutaneous and intramuscular injections can be done at home. It should be remembered that the introduction of the drug is painful.

For injections, a 1%, 2.5% and 5% solution is used, which is administered once a day. The dosage of the drug is calculated taking into account the content of nicotinic acid in it.

Usually, for the treatment of pellagra, 50 mg of a solution is used intravenously or intramuscularly for 10 days.

Nicotinic acid for hair

This method of strengthening hair cannot be recommended by the attending physician. It is better known as a traditional medicine and can only be used as a recommendation.

Nicotinic acid is known for its vasodilating properties. When applying the drug to the scalp, the hair follicles are enriched with nutrients. To strengthen the hair, the drug is used for 30 days.

According to the recommendations, a small amount of nicotinic acid inflict on the scalp. The agent is rubbed with light movements. One ampoule is used per application. The drug is applied to the hair in a small amount on the temples, the back of the head and parting.

For convenience, the medicine can be poured into a plastic container and applied with fingertips.

If the dose is exceeded, that is, the use of more than one ampoule, an allergy may develop, which is accompanied by redness skin. It should be borne in mind that redness is possible after each application of the product. The therapeutic effect of using the product will be noticeable after a short time.

The preparation of nicotinic acid can be mixed with juice, egg yolk, burdock oil to obtain a healing masks. The mask should be applied after shampooing along the entire length of the hair. It is applied for one hour, repeated use is possible within a week or with short breaks.

You can also make your own shampoo with a medicinal effect. To do this, you need to mix 10 ml of nicotinic acid with 10 ml of ready-made shampoo, which is applied for 15 minutes to washed hair.

As a result of using the tool, it improves condition hair and scalp.

Nicotinic acid during pregnancy

The use of nicotinic acid preparations during pregnancy, according to experts, is carried out only as directed by a doctor, taking into account the possible risk of harm to the fetus, possible side effects and the method of using the drug.

During lactation, the use of the drug is possible with the complete cessation of breastfeeding.

Nicotinic acid side effects

The use of nicotine, like any drug, can cause a number of side effects. action.

These symptoms resolve on their own and do not require treatment.

• With intravenous use of nicotinic acid, a decrease in blood pressure is possible; with prolonged use, fatty hepatic degeneration may develop.

Overdose

In the event of a lack or overdose of vitamin PP in the body, symptoms may develop that are associated with an unfavorable state of the body caused by a lack or excess of the vitamin.

• Usually, a deficiency of nicotinic acid is accompanied by general weakness, apathy, increased fatigue, headaches and dizziness, sleep disturbance, weight loss and lack of appetite, dry skin, impaired stool, decreased immunity.
• With a prolonged lack of nicotinic acid, the patient may develop pellagra, which is characterized by chronic diarrhea, discomfort in the stomach, burning sensation in the mouth, increased salivation, redness of the mucous surfaces, cracks on the surface of the tongue. Numerous inflammations appear on the surface of the skin, the skin on the elbows and joints becomes covered with red spots. Patients experience numbness of the arms and legs, there is a feeling of "goosebumps" on the body.
• Prolonged use of a drug containing nicotinic acid can cause fainting, itchy skin, impaired cardiac activity and the functioning of the gastrointestinal tract.

Analogues

As an active substance, nicotinic acid is part of Apelagrin, Niacin, Nicoverin, Nicotinic acid bufus, Enduracin.

Nicotinic acid price

You can buy Nicotinic acid in pharmacies with a doctor's prescription. The drug is inexpensive. The average price for a pack of tablets is from 20 rubles and 50 rubles for an injection solution.

Nicotinic acid reviews

Nicotinic acid was taken as prescribed by a neurologist to normalize blood flow in the vessels. The use of the drug passed without side effects, as it was used strictly according to the instructions.

I was prescribed Nicotinic acid for the treatment of vegotovascular dystonia in combination with other drugs. After the first injection, there was a slight reddening of the face, but the doctor warned about the possible effect of the medicine. After using the drug, headaches disappeared, the general condition improved, tinnitus disappeared.

To relieve headache attacks, the doctor advised taking nicotinic acid tablets to dilate blood vessels. After the first use, I began to feel much better. After a full course of pain stopped. Of the side effects, only reddening of the face was noted.

Nicotinic acid in the form of injections should be taken on the advice of a doctor.

Indications for use

• violation of the patency of the blood vessels of the extremities,
• in case of problems with cerebral circulation,
• haemorrhoids,
• osteocondritis of the spine,
• a hereditary disease in which there is a problem with the absorption of certain amino acids (Hartnup's disease),
• lack of vitamin PP,
• diabetes,
• decreased vision,
• infectious diseases,
• disorders in the extremities associated with vasospasm,
• liver disease,
• ischemic stroke,
• noise in ears,
• inflammation of the facial nerve
• lipid metabolism problems
• skin diseases,
• with disorders in the digestive system,
• glucose intolerance,
• intoxication:
  • medical,
  • alcoholic,
  • professional,
• high acidity,
• in order to prevent obesity and diseases caused by vascular disorders.

Contraindications

• exacerbation of peptic ulcer
• drug intolerance,
• cirrhosis of the liver,
• atherosclerosis,
• if, in case of violations of blood sugar levels, it is not corrected by drugs,
• excess levels of uric acid in the blood.

Nicotinic acid is used to treat, but with caution in case of:

• low blood pressure,
• hemorrhage,
• pregnancy,
• glaucoma,
• childhood,
• peptic ulcer in remission,
• lactation.

Side effects

• lowering blood pressure,
• exacerbation of disorders of the functioning of the stomach,
• deterioration of the liver and kidneys,
• possible temporary manifestations:
  • nettle rash,
  • prostration,
  • dizziness,
  • lack of appetite,
  • redness of the face.

The benefits of nicotinic acid in injections for osteochondrosis

Spinal aging is another name for this disease. The loss of the normal state of the disc, a change in its anatomical position as a result of subsidence or improper loading gives the prerequisites for the occurrence of osteochondrosis.

In the future, a violation of the dislocation of the vertebrae is possible.

All these changes lead to pinching and inflammation of the nerve roots and failure of the organs for which they are responsible.

Niacin is useful for osteochondrosis because:

• It is a vitamin and replenishes the lack of nicotinic acid in the body. Good nutrition is an important factor in the prevention of osteochondrosis and its treatment.
• Improves blood circulation, which stimulates tissue nutrition.
• Protects cells from free radicals, which protects them from damage.
• Removes toxins, which heals and rejuvenates body tissues.
• It improves all metabolic processes, which contributes to the supply of necessary substances to the tissues and the removal of waste slags.
• Makes the restoration of the structure of neurons, which helps the nervous tissue to be updated and resist inflammatory processes.

Instructions for use: dosage and treatment regimen

The maximum dose of the drug prescribed for an adult:

How to inject injections

The drug in the form of injections is administered:

With the rapid introduction of the drug intravenously - the sensations resemble how calcium chloride is administered when the drug is administered, but with less force. There is redness of the face and skin of the upper body. There is a sensation of heat. The symptoms go away on their own. To avoid them, the drug should be administered slowly and after meals.

Due to the fact that the injections are painful, nicotinic acid is often prescribed intravenously.

Pharmacy price

Packing of the drug - 10 ampoules. The content of the solution in one ampoule is 1 ml. The cost of a box with niacin ampoules is within the limits of rubles.

Reviews about the drug

There is a noticeable positive effect of the drug: vascular problems are normalized. The accompanying sensations of cold, tingling disappear.

The use of niacin (another name for nicotinic acid) provides quick relief from pain in the spine that accompanies osteochondrosis. There is clarity in the mind.

Patients note that during the course of treatment, skin rejuvenation occurs, it becomes a healthy pink color. If there are wounds, scratches, cuts on the skin, they heal together. Hair grows well and becomes lush.

When treating with nicotinic acid, immunity is strengthened, energy appears. Patients report a surge of energy. Vision improves.

Nicotinic acid in ampoules - can it be administered intramuscularly, how?

Nicotinic acid in ampoules - can it be administered intramuscularly (how - with saline / novocaine or directly)? Is it possible to drink nicotinic acid for injection (how - diluted or not, how many times)?

ZVENKA respect for the instructions for use! - 2 years ago

Nicotinic acid 1%, 1 ml, administered intramuscularly daily, without dilution, can be injected intradermally into the arm. It is not necessary to dilute for administration, it is ineffective to take it in the form of a drink. There are increasing schemes: every day, 1 ml, adding 4 ml, up to 5 ml, 5 ml for 3 days and leaving in the same decreasing pattern. Some are hard to bear, due to side effects in the form of reddening of the skin and a burning sensation, palpitations and interruptions in the work of the heart.

Nicotinic acid is prescribed for diseases of the nervous system, vascular diseases and as a derivative of vitamin "PP", vitamin B3, niacin. Carry out a course of intramuscular injections of Nicotinic acid No., then take 0.05 mg tablets 1 tablet x 3 times a day for up to 3-4 weeks. This will be a good course.

Large studies have been carried out on the effect of nicotinic acid on lipid metabolism (metabolism of fats and cholesterol fractions).

This allows you to effectively use it in many diseases.

Indications and use

• ischemic stroke;
• noise in ears;
• atherosclerosis;
• pellagra;
• haemorrhoids;
• liver disease;
• alcohol intoxication;
• drug intoxication;
• decrease in visual acuity.

• reduced risk of developing cancer;

The use of vitamin nicotinic acid

The use of the drug in ampoules

Nicotinic acid injections help to quickly introduce the drug into the human body and ensure its uniform distribution. Nicotinic acid in injections helps to avoid such negative side effects as an irritant effect on the gastric mucosa. Nicotinic acid in ampoules is prescribed for:

• increased acidity of gastric juice;
• in acute disorders of cerebral circulation of an ischemic nature;
• with pain syndromes in the trigeminal nerve and spine;
• with acute attacks of hemorrhoids.

Nicotinic acid is available in ampoules of 1 ml of a 1% solution. Usually prescribed 1 ampoule subcutaneously, intramuscularly or intravenously once or twice a day.

How to give injections

Nicotinic acid injections can be given in three ways:

• intramuscularly, 1 ml of a 1% solution;
• intradermally when compensating for vitamin deficiency;
• intravenously, 1-5 ml of a 1% solution diluted in 5 milliliters of saline.

Intramuscular and intradermal injections of nicotinic acid are quite painful. There is a burning sensation. After an intravenous injection of nicotinic acid, fever and redness of the skin may be felt. This is a normal physiological reaction of the body. If redness is not observed, then this may indicate that a person has certain problems with blood circulation.

Use of the drug in tablets

Nicotinic acid preparations in tablets can be used for prevention and for the long-term treatment of certain diseases. In particular, nicotinic acid tablets are recommended to be used twice a year, in spring and autumn, for 1 month, for people who suffer from circulatory problems in the lower extremities. Thrombophlebitis and venous insufficiency is a direct indication for the use of nicotinic acid in tablets for a long time.

The drug nicotinic acid in tablets is used depending on the weight of the person and the severity of the disease, 1-2 tablets 3 times a day. It is advisable at this time to introduce cottage cheese and other foods rich in methionine into your diet. This will help protect the liver cells. With increased acidity of gastric juice, nicotinic acid tablets should be taken after meals and washed down with plenty of mineral water or warm milk.

Contraindications

Electrophoresis for osteochondrosis

Action on intoxication

Taking nicotinic acid for osteochondrosis

The complex substance nicotinic acid refers to stimulant drugs. Its characteristics make it possible to effectively use the drug against osteochondrosis. It is enough to strictly follow the sequence of application and dosage in order to achieve a sustainable result.

Nicotinic acid in osteochondrosis is prescribed as a preventive or main means of dealing with the problem. The reason for the appointment may be:

• osteochondrosis of the chest, cervical, lumbar;
• exacerbation of the disease;
• pain symptoms;
• dizziness;
• noise in ears.

Only a doctor should prescribe drugs containing this acid.

Non-standard use of a vitamin supplement

The cosmetic industry considers the product as rejuvenating and tonic. By changing the dosage, experts achieve a change in the condition of the skin.

The principle of operation of the tablet form, with osteochondrosis, is built on the following principles:

• vasodilation;
• providing tissues with a large amount of oxygen due to the influx of fluids;
• output of metabolic products and waste material;
• stimulation of the metabolic work of the integument.

Possessing anti-allergic mechanisms of action, it stimulates various body systems. As evidenced by the additional marking PP.

Dosage of the drug

The course of nicotinic acid for osteochondrosis is prescribed by the doctor based on the severity of the patient's condition. The drug has two forms:

The pill regimen consists of a fifteen or twenty day course. They are taken only after meals. An adult is prescribed 1 tablet, 2 to 4 times a day. Sometimes this dose is increased gradually.

Injections are made from the proportions of 0.5 ml of a one percent solution once a day. Up to 1 ml is applied once. Proportions are calculated based on the patient's age and weight.

Solution for injections

Ampoules of the substance come with a concentration of 1%. The average amount administered per day is 10 ml. The duration of the appointment of therapy days. In chronic diseases, the dose may be increased to 300 mg.

Important! The decision to use injections should only be made by a qualified specialist. In no case do not self-medicate.

How to inject with a solution of nicotinic acid

The solution is introduced gradually, introduced with a syringe or dropper. There are three main ways to introduce a substance into the body:

No more than 1 ml is injected into the muscle fiber. Dropper or injection is introduced into the vein up to 5 ml. In this case, a solution mixed with saline is prepared. Proportion 1 ampoule ml. A dropper is prescribed at least two doses per day, based on the picture of the development of the disease.

Acid in the form of tablets

Effective nicotinic acid in tablets for osteochondrosis with a long course. The course of treatment is most often repeated 2 times a year. By stimulating blood circulation, the agent gently affects the peristatics of the walls of blood vessels.

There is a gradation of the volume of the substance depending on the violation:

• vitamin PP deficiency - 2 tablets three times after meals;
• osteochondrosis of the cervical and thoracic spine - 1 tablet three times a day, the period of taking up to a month.

During the period of taking the patient feels a burning sensation of the skin, a feeling of temperature increase. This effect is strongest in places of fluid stagnation.

Combination of electrophoresis with nicotinic acid

The accumulation of lactic acid in the affected areas accelerates the trophism of the disease. Treatment of osteochondrosis with nicotinic acid is more effective in combination with electrophoresis. Such a tandem gives quick results:

• the level of inflammation of muscle tissue decreases;
• the tone of blood vessels increases;
• removal of excess fluids;
• decomposition products are removed.

During the procedure, the active components of the substance are quickly delivered to the site. There is a rapid saturation of the muscles with acid components.

The drug for osteochondrosis of the cervical

Osteochondrosis of the cervical region is manifested by severe pain and dizziness. Since the degradation of the intervertebral discs stimulates the appearance of a hernia, it is necessary to take emergency measures at the first symptoms.

The first alarming symbols of the disease:

Impaired blood flow to the brain causes sleep disturbances, anxiety and irritability. There is a group of methods for dealing with problematic manifestations. Each is based on a group of factors identified during the survey.

In case of significant poisoning of the body with various components, a rapid removal of the substance from the body is required. A course of taking pills is prescribed. The active component binds radicals and groups of toxins, stimulating their elimination. For toxic damage from other causes, intramuscular injections are prescribed.

Contraindications for the use of nicotinic acid

Substances in the composition of the drug can cause allergic reactions. This shows up as:

Also, treatment with this drug is undesirable in the following cases:

• hypersensitivity to the components of the drug;
• atherosclerosis;
• hepatitis;
• cirrhosis of the liver;
• gout;
• diabetes.

An excess of a substance in the blood can affect the condition of the intestines, disrupt its work. In this case, there will be a strong rush of blood to the upper body.

When choosing any methods of treatment for a disease such as osteochondrosis, remember that only a doctor should decide on taking any drugs. Do not self-medicate, take care of your health.

Nicotinic acid for injection

Nicotinic acid, or vitamin B3, is produced by both foreign and domestic pharmaceutical companies. The main active ingredient of the drug is nicotinic acid, while each milliliter of the drug contains 10 milligrams of this vitamin, and the tablet contains 0.05 grams of the main component.

The documents indicate that the solution is clear, colorless, has a pH value of 5-7. Pharmaceutical companies produce vitamin PP in the form of a solution for injections and tablets.

Pharmacological characteristics

Instructions for use describe that nicotine has the following properties:

Vitamin PP is a substance that takes part in oxidation reactions that occur in large quantities in the cells of a living organism. This substance has a specific effect - antipelargic and can be used to improve the functioning of the vessels through which blood moves.

The main purpose of nicotinic acid:

• normalization of the permeability of the walls of blood vessels;
• reduction of puffiness;
• improvement of tissue metabolism and microcirculation;
• expansion of the vascular lumen;
• increased fibrinolytic activity of plasma;
• reduction in platelet aggregation.

In the process of metabolism, vitamin PP undergoes biotransformation processes and nicotinamide is formed, which interacts with the coenzymes responsible for oxygen transfer.

Nicotinic acid is almost completely absorbed in the digestive tract. Metabolism occurs in the liver, and products are excreted in the urine. It should be noted that while taking high doses, the main component of the drug does not undergo metabolization, but is excreted to a greater extent unchanged.

Indications

• lack of vitamin B3, which arose as a result of parenteral nutrition or other ailments;
• fever that lasts a very long time;
• hyperthyroidism;
• oncological diseases;
• hyperlipidemia;
• atherosclerosis;
• spasm of the urinary and biliary tract;
• microangiopathy;
• diabetic polyneuropathy;
• hypoacid gastritis;
• neuropathy of the facial nerve;
• ulcers and wounds that do not heal for a very long time.

Contraindications

Also, the instructions for use describe that contraindications to prescribing the drug is the presence in the patient's history of:

Side effects

Since during the treatment of diseases using this drug, histamine release is stimulated, patients note the appearance of:

During prolonged use of high dosages of the drug develop:

• anorexia;
• disruption of the liver;
• gagging;
• stomach upset;
• irritation and ulcers of the mucous organs of the gastrointestinal tract;
• paresthesia;
• violation of the heart rhythm;
• reduced glucose tolerance;
• hyperglycemia.

Doses and regimens

The method of administration and dosage of this medication directly depends on the disease and its neglect.

If the patient has an ischemic stroke, the dose of the drug is in the range of 0.01-0.05 grams.

After an intravenous or intramuscular injection, patients report fever, burning, and redness. This reaction is absolutely adequate and indicates the absence of problems with blood circulation.

Overdose

If you enter a dose of the drug, which significantly exceeds the permitted, the patient begins to feel the following symptoms:

• blood rushes to the head;
• the skin itches;
• dyspeptic disorders appear.

The first aid for this condition is symptomatic treatment.

Interaction

Vitamin PP has the ability to enhance the effect of drugs of the group of ganglionic blockers, which contributes to the development of orthostatic pressure reduction.

Since the components of bile acids can reduce the bioavailability of nicotinic acid, this drug is taken several hours before or after a meal.

Also, during treatment, a false-positive result of the reaction can occur with the use of Benedict's reagent, which is used to determine the amount of glucose in the urine.

Vitamin B3 has a hyperglycemic potential and can reduce the activity of acarbose, which is the cause of decompensation of diabetes mellitus. This is the reason why when prescribing nicotinic acid with Metformin and Saxagliptin, you need to regularly monitor blood sugar levels.

It is important to control blood clotting parameters when combining vitamin PP with calcium nadroparin.

Myopathy and rhabdomyolysis develops with a combination of nicotinic acid with statins and amlodipine. It is not recommended to combine vitamin B3 with ascorbic acid.

The instruction describes that it is strictly forbidden to inject vitamins PP and B1 in one syringe.

With alcohol

Since the main component of the drug stimulates the excretion of heavy metal ions and a certain amount of toxic compounds from the blood, it is often used to eliminate the symptoms of alcohol poisoning.

During pregnancy

Women during the period of gestation, as well as during lactation, should not take large doses of this drug.

Acquisition

Tablets and injections of nicotinic acid are sold from a pharmacy only after presenting a prescription from the attending physician, which indicates the dose, frequency of administration and course of treatment with the drug.

Storage

It is not difficult to store this medicine. To do this, it is enough to protect the drug from direct sunlight at a temperature not exceeding 25 degrees, and also away from children.

Nicotinic acid injections are stored for no more than 5 years. The end date is indicated on the packaging. After this period, the use of the drug is prohibited, and it must be disposed of.

Analogues

This drug in tablets and ampoules is admitted by many pharmaceutical companies. The only analogue that has a combined composition: nicotinic acid and drotaverine is called Nikoshpan.

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Nicotinic acid instructions for use

The drug nicotinic acid refers to vitamin derivatives of pharmacological production. This drug has a number of actions on the human body.

This allows you to effectively use it in many diseases.

Among the positive effects of nicotinic acid on the human body, the following should be noted:

• metabolic action leads to the normalization of metabolic processes, the restoration of the neural structure;
• as vitamin nicotinic acid and instructions for use contain this information, is responsible for lipid and carbohydrate metabolism in the human body;
• also, injections and tablets of nicotinic acid are able to restore impaired blood supply to certain parts of the body and human brain;
• vasodilation, which occurs under the influence of nicotinic acid, leads to the normalization of oxygen metabolism and oxidative processes;
• also nicotinic acid is able to have a detoxifying effect, so it can be used for poisoning and alcohol consumption.

These are not all the positive properties of nicotinic acid. The instructions for use that we offer you will help you deal with all the therapeutic effects. We hope to help you evaluate and use this drug.

The drug nicotinic acid indications for use is quite extensive. This drug can be taken both for medicinal purposes and for the prevention of many diseases.

In particular, nicotinic acid is used for medicinal purposes in such diseases and conditions:

• osteochondrosis of the spinal column of various departments;
• ischemic stroke;
• violation of cerebral circulation;
• noise in ears;
• atherosclerosis;
• pellagra;
• impaired glucose tolerance;
• circulatory disorders in the lower extremities;
• haemorrhoids;
• lipid metabolism disorders and obesity;
• liver disease;
• alcohol intoxication;
• drug intoxication;
• professional intoxications;
• trophic ulcers of the lower extremities;
• decrease in visual acuity.

For prevention, nicotinic acid is used in:

• reduced risk of developing cancer;
• rapid breakdown of fats and a decrease in the level of intake of fatty acids in the human body;
• with gastritis with low acidity;
• to eliminate the symptoms of hemorrhoids;
• to improve memory and vision;
• to accelerate the process of splitting fats during weight loss.

The use of nicotinic acid requires careful monitoring by the attending physician. Self-treatment with nicotinic acid is not allowed due to the fact that negative consequences may develop in the human body. Like any other vitamin preparation, when overdosed, it causes irreparable damage to your health.

Very often, vitamin nicotinic acid finds non-standard use. In particular, this drug is very often used to rejuvenate and renew the skin of the face and body in many beauty salons. In fact, this is a completely justified method only if the treatment is carried out under the supervision of an experienced doctor.

Nicotinic acid indications in this case are very different. However, the principle of influence is quite simple.

This drug has a unique ability:

• on the one hand, expand the vessels of the peripheral circulatory system;
• on the other hand, it increases the supply of oxygen to tissues;
• on the third hand, it increases the outflow and removal of free radicals and aggressive toxins from skin cells.

Together, this has a rejuvenating effect on the human body. This is best seen on the skin. The skin becomes smooth, moisturized and gets a pleasant pink tint.

Benefit or harm

The drug "Nicotinka" (injections): when it is needed

Nicotinic acid or, as it is also called, “Nicotinka” (shots) refers to vitamin-like substances. The strength of its vessels and the normal functioning of the circulatory system depend on the content of this vitamin in human blood. That is why the medicine is so often used in modern medicine.

The drug "Nicotinka" (injections): pharmacological properties

Nicotinic acid (vitamin PP) is very important for the normal functioning of all human organ systems. Once in the body, it is quickly converted into nicotinamide - a substance that is involved in the metabolism of fats, lipids, proteins, purines. Nicotinamide is also important for the normal transport of hydrogen ions.

Nicotinic acid affects the concentration of lipoproteins in the blood, and in certain doses it can lower cholesterol levels.

The drug "Nicotinka" improves the microcirculation of the brain, and also partially increases the fibrinolytic activity of the blood.

It is worth noting that with a deficiency of nicotinic acid in the body, the development of a disease called pellagra begins. Therefore, the drug is used both for the treatment of the disease, and as a preventive measure.

The drug "Nicotinka" (injections): instructions for use

To date, the drug "Nicotinic acid" has become quite widespread among medical staff. Of course, it is primarily used for the prevention and treatment of pellagra, but its significance does not end there.

It has already been mentioned that this vitamin has a positive effect on the circulatory system, especially on the blood supply apparatus of the brain. Therefore, the drug "Nicotinic acid" is used in the presence of spasm of peripheral vessels, as well as in ischemic stroke. It is also prescribed for chronic migraines, as well as for the treatment of atherosclerosis.

In some cases, this medicine is used as part of complex therapy in the treatment of infectious diseases, disorders of the digestive tract, and hypercoagulability. The drug is effective in the presence of neuritis of the facial nerve.

The drug "Nicotinka": instructions for use

This tool is not recommended to be taken on its own - for starters, you should consult a doctor. The specialist will determine the dose, mode of administration and route of administration. The solution can be administered subcutaneously, intramuscularly or intravenously. It is believed that injections are quite painful, especially intramuscular ones.

The daily dose of the drug depends on the type of disease and its severity. For preventive purposes, adults are recommended to enter 0.025 g of vitamin per day. For children, the dose is less - from 0.005 to 0.025 g per day.

If pellagra has already begun, then the daily dose is recommended to be increased. Adults should be administered from 0.05 g intravenously 1-2 times a day. Treatment in this case lasts from 10 to 15 days.

The drug "Nicotinka" (injections): contraindications

Firstly, this medicine is categorically contraindicated for those patients who have developed hypersensitivity to nicotinic acid. Secondly, it is not recommended for people with diabetes.

On the other hand, the drug is not used to treat patients with severe atherosclerosis or hypertension. Exacerbation of an ulcer of the intestine or stomach can also be a contraindication. It is not recommended to use this remedy in the presence of gout or severe liver disease. During pregnancy and lactation, the use of the drug should be very careful.

The drug "Nicotinka" (shots): side effects

Adverse reactions are recorded quite rarely, but all of them are somehow associated with the active release of histamine. For example, a patient complains of dizziness, a feeling that blood is rushing to the head. Diarrhea, nausea, vomiting and other disorders of the digestive tract are sometimes observed.

How to inject nicotine

Nicotinic acid is vitamin PP or B3. This drug is prescribed to improve lipid metabolism, lower cholesterol levels, etc. Nicotinic acid is most often prescribed for a two-week course, it can be injected in the same doses throughout the course or according to a certain scheme.

Instruction

1. For the treatment of various diseases, a course of nicotinic acid of different duration and doses is recommended. So in the treatment of pellagra (a metabolic disease that occurs due to a lack of vitamin PP), the maximum course of this drug is prescribed. With pellagra, 2-4 ml of nicotinic acid diluted in 200 ml of isotonic solution is injected intravenously. Those. in a 200 ml bottle with a 0.9% sodium chloride solution, inject 2 to 4 ml of nicotine as prescribed by a doctor and connect a dropper with an induced solution to the patient. In severe cases of the disease, a dropper with nicotinic acid is placed twice a day - in the morning and in the evening. The course of treatment prescribed by a doctor is days.
2. In diseases of the liver and pathology of the gastrointestinal tract (peptic ulcer, gastritis of various etiologies), nicotinic acid is prescribed in 0.5-1 ml subcutaneously or intramuscularly. For intramuscular injection of this drug, adults need to use the needle that comes with the 5 ml syringe. And the needle that comes with the 2 ml syringe is more suitable for intradermal injection of the solution. The course of treatment on the recommendation of doctors is 7-10 days. With these diseases, it is desirable to repeat the therapeutic course of nicotinic acid 2 times a year, until the period of seasonal exacerbations, i.e. in September and March.
3. To improve metabolic processes in the body in mild forms of diabetes mellitus, atherosclerosis, hyperlipidemia, as well as to reduce spasms of peripheral vessels in obliterating endarteritis, migraine, Raynaud's disease, etc., it is recommended to inject nicotinic acid solution intramuscularly according to a certain scheme. Start with small doses of the drug - from 1 ml, then bring to the maximum single dose of administration - 5 ml, then reduce the dose. Thus, on the first day of therapy, you need to inject 1 ml of vitamin B3, on the second - 2 ml, on the third - 3 ml, on the fourth - 4 ml, on the fifth day you enter the maximum dose - 5 ml, and from the sixth day you begin to reduce the dose , i.e. on the sixth day - 4 ml, on the seventh - 3 ml, on the eighth - 2 ml, on the last ninth day of the treatment course you inject 1 ml of nicotinic acid.
4. Be sure to keep in mind that nicotinic acid is a vitamin, so it is better to inject with its solution after eating, because. acid binds with other nutrients and passes into the compound nicotinamide, which is very valuable for the body, because. participates in lipid metabolism and normalizes blood cholesterol levels. Like many vitamins, nicotine causes pain when administered parenterally. If you know the technique of intramuscular injections and will inject vitamin PP yourself, then try to inject the drug very slowly to reduce the painful feeling from the injection.

Nicotinic acid tablets: properties and uses

Today we offer a closer look at such a broad-spectrum drug as nicotinic acid. This tool is successfully used not only for the treatment of a number of diseases, but also for weight loss, as well as improving the condition of the hair.

Nicotinic acid tablets: pharmacology

This drug is a very important vitamin for the human body, which contributes to the normal course of the overwhelming number of educational and metabolic processes. Nicotinic acid improves liver function, helps heal wounds and ulcers, promotes hematopoiesis in the bone marrow, reduces the risk of vascular spasms, activates the motility of the gastrointestinal tract and the production of the gastric mucosa, facilitates the detoxification process, and reduces the concentration of glucose in the blood. In addition, the use of this drug has a positive effect on the functioning of the cardiovascular, as well as the nervous system. Nicotinic acid in tablets has a beneficial effect on lipid metabolism, and also helps to reduce blood cholesterol levels in patients with atherosclerosis and hypercholesterolemia. Very effective is the use of this drug in pellagra. However, the full list of useful properties of nicotinic acid is not limited to the listed items. Thus, this substance is effective as an antipruritic, desensitizing, detoxifying and vasodilator. In addition, nicotinic acid tablets are also used for weight loss.

Indications for use

Nicotinic acid in tablets is prescribed by doctors for various liver diseases, multiple sclerosis, as well as for endarteritis and processes accompanied by angiospastic phenomena. In addition, this drug is often used in the treatment of diseases of the skin and mucous membranes: eczema, lupus erythematosus, photodermatosis, dermatitis, psoriasis, neurodermatitis, glossitis, skin porphyria and others. This tool is also effective in the treatment of dermatosis, leading to disorders of the peripheral circulation. This drug is also used as a detoxifying agent for sulfonamide poisoning, as well as for prolonged therapy using anti-tuberculosis and antimalarial drugs. Nicotinic acid also helps in diagnostic measures to detect erythema leprous or syphilitic roseola.

Nicotinic acid (tablets): instruction

Since this drug is used to treat various diseases, it is important to prescribe the correct dosage. Only a qualified doctor can do this. As a rule, nicotinic acid tablets are prescribed in a dosage of 0.02 to 0.1 grams at a time three times a day. The drug should be taken after meals. For prevention purposes, nicotinic acid is prescribed at a dosage of 0.015-0.025 grams three times a day (for adult patients) and 0.005-0.02 grams per day (for children). Depending on the type of disease and the condition of the patient, the duration of therapy using this drug can be 3-5 weeks. If it is necessary to conduct a second course of treatment, it should be started no earlier than every other day.

Side effects

Nicotinic acid tablets, reviews of which are overwhelmingly positive, are usually very well tolerated by patients. Nevertheless, for the first time after the start of taking the drug, side effects may develop in the form of an increase in body temperature and reddening of the skin of the face. Such symptoms quickly pass and do not cause any particular inconvenience to the patient. In the case of long-term use of nicotinic acid, stomach diseases can worsen, as well as disorders in the liver and kidneys. In order to prevent such complications, patients are additionally prescribed the drug "Methionine", and it is also recommended to eat cottage cheese more often. As for contraindications, in no case should nicotinic acid be used by people who have an individual intolerance to this substance. For all other groups of patients, this drug is quite safe. In addition, it is successfully used by both pregnant women and children.

What doctors are silent about. . Nicotinic acid and in cosmetology

What is vitamin B3 and how is it eaten?

American scientists have found that the most powerful vitamin that resists all kinds of infections is B3. Studies have shown that this vitamin is able to cope with bacteria, in front of which most of the existing drugs are powerless.

Intense neuropsychic activity (pilots, dispatchers, telephone operators)

In the conditions of the Far North

Working in hot climates or in hot workshops

Pregnancy and lactation

Low-protein diet and the predominance of vegetable proteins over animals (vegetarianism, fasting)

Signs of a lack of Vitamin B3 - lethargy, apathy, fatigue

Dizziness, headache

Decreased appetite, weight loss

Pale and dry skin

Decreased body resistance to infections

Diarrhea (stools 3-5 or more times a day, watery without blood and mucus)

Loss of appetite, heaviness in the stomach

Burning in the mouth, drooling

Redness of the mucous membrane

Puffiness of the lips and the appearance of cracks on them

The papillae of the tongue protrude as red dots and then smooth out

Deep cracks in the tongue

Red spots appear on the hands, face, neck, elbows

Swelling skin (sore, itchy, and blistering)

Severe weakness, tinnitus, headaches

Feelings of numbness and crawling

The drug nicotinic acid refers to vitamin derivatives of pharmacological production. This drug has a number of actions on the human body.

Among the positive effects of nicotinic acid on the human body, the following should be noted:

• metabolic action leads to the normalization of metabolic processes, the restoration of the neural structure;
• as vitamin nicotinic acid and instructions for use contain this information, is responsible for lipid and carbohydrate metabolism in the human body;
• also, injections and tablets of nicotinic acid are able to restore impaired blood supply to certain parts of the body and human brain;
• vasodilation, which occurs under the influence of nicotinic acid, leads to the normalization of oxygen metabolism and oxidative processes;
• also nicotinic acid is able to have a detoxifying effect, so it can be used for poisoning and alcohol consumption.

Nicotinic acid indications and use

The drug nicotinic acid indications for use is quite extensive. This drug can be taken both for medicinal purposes and for the prevention of many diseases.

In particular, nicotinic acid is used for medicinal purposes in such diseases and conditions:

• osteochondrosis of the spinal column of various departments;
• ischemic stroke;
• violation of cerebral circulation;
• noise in ears;
• atherosclerosis;
• pellagra;
• impaired glucose tolerance;
• circulatory disorders in the lower extremities;
• haemorrhoids;
• lipid metabolism disorders and obesity;
• liver disease;
• alcohol intoxication;
• drug intoxication;
• professional intoxications;
• trophic ulcers of the lower extremities;
• decrease in visual acuity.

For prevention, nicotinic acid is used in:

• reduced risk of developing cancer;
• rapid breakdown of fats and a decrease in the level of intake of fatty acids in the human body;
• with gastritis with low acidity;
• to eliminate the symptoms of hemorrhoids;
• to improve memory and vision;
• to accelerate the process of splitting fats during weight loss.

Like any other vitamin preparation, when overdosed, it causes irreparable damage to your health.

Vitamin nicotinic acid finds non-standard application

Very often, vitamin nicotinic acid finds non-standard use. In particular, this drug is very often used to rejuvenate and renew the skin of the face and body in many beauty salons. In fact, this is a completely justified method only if the treatment is carried out under the supervision of an experienced doctor.

Nicotinic acid indications in this case are very different. However, the principle of influence is quite simple.

This drug has a unique ability:

• on the one hand, expand the vessels of the peripheral circulatory system;
• on the other hand, it increases the supply of oxygen to tissues;
• on the third hand, it increases the outflow and removal of free radicals and aggressive toxins from skin cells.

Together, this has a rejuvenating effect on the human body. This is best seen on the skin. The skin becomes smooth, moisturized and gets a pleasant pink tint.

The drug nicotinic acid dosage

Nicotinic acid tablets

Nicotinic acid preparations in tablets can be used for prevention and for the long-term treatment of certain diseases.

In particular, nicotinic acid tablets are recommended to be used twice a year, in spring and autumn, for 1 month, for people who suffer from circulatory problems in the lower extremities. Thrombophlebitis and venous insufficiency is a direct indication for the use of nicotinic acid in tablets for a long time.

The drug nicotinic acid in tablets is used depending on the weight of the person and the severity of the disease, 1-2 tablets 3 times a day. It is advisable at this time to introduce cottage cheese and other foods rich in methionine into your diet. This will help protect the liver cells.

Nicotinic acid tablets should ALWAYS be taken after a meal. and drink plenty of water.

The drug nicotinic acid contraindications

Vitamin nicotinic acid has minor contraindications. Usually this drug is not recommended for use in:

• individual intolerance to vitamin PP;
• with acute liver diseases;
• with liver failure;
• with exacerbation of gastric ulcer;
• with high blood pressure.

Also, nicotinic acid may have contraindications in a number of individual cases. Only a doctor can determine the appropriateness of using nicotinic acid in one form or another.

Electrophoresis with nicotinic acid in osteochondrosis

The appointment of electrophoresis with nicotinic acid in osteochondrosis helps to quickly remove accumulations of lactic acid from the tissues affected by the inflammatory process. This reduces swelling and eliminates pain. Also, electrophoresis with nicotinic acid is able to provide faster entry of other drugs into the affected area. This becomes possible due to the fact that blood flow increases, and the tissues are better supplied with oxygen and nutrients. Accordingly, the healing process is much faster.

Most often, electrophoresis with nicotinic acid is prescribed 1 time per day for ten days.

Effective treatment with nicotinic acid

To obtain the maximum effect, treatment with nicotinic acid should be started only after a complete examination of the state of health. The maximum effect is achieved only if a certain condition is associated with a lack of this vitamin in the human body.

The second principle is persistence. Treatment with nicotinic acid should be carried out in the form of courses. A single dose does not help. Only a constant intake according to the scheme prescribed by the doctor can give you a lasting therapeutic effect.

The action of nicotinic acid in intoxication

Scientists and practitioners have long noticed the positive effect of nicotinic acid in various intoxications. Nicotinic acid instructions for use take this into account, helps to quickly remove toxic substances from the human body. It binds free radicals and neutralizes the effects of toxic substances on target organ cells.

Nicotinic acid is widely used in this capacity in the removal of a hangover syndrome, in the treatment of alcoholism and drug addiction, and in occupational harmful effects.

The drug nicotinic acid: the price is affordable for everyone

Nicotinic acid has an amazing benefit. This drug at its cost is available to almost everyone. For nicotinic acid, the price is currently around 20 rubles for 1 pack of injections or tablets. The course of treatment requires no more than 3 packs. So consider how nicotinic acid and the price correspond to their useful qualities. Use affordable drugs and be healthy.

http://www.glamour.ru PRIVATE OPINION

I heard about this vitamin again during an interview with cosmetologist Tiina Orasmäe-Meder, an expert on cosmetic safety at the European Parliament -. Answering my question: “What are your favorite ingredients in cosmetics?” Tiina said: “Nicotinka”.

“I have been prescribing it to patients with decreased muscle tone for many years. I learned about this technique from California plastic surgeons - they recommend that patients drink a course of nicotinic acid before surgery so that the skin recovers faster. I often advise my clients to take the course when their skin looks tired and dull, a problem that is especially common in smokers.”

I rushed to the pharmacy for nicotinic acid. The best part is that the issue price is about 20 rubles. And honestly drank a two-week course. My observations are that the skin really immediately turns slightly red (as if you are suddenly embarrassed) and “burns” a little, but this reaction disappears within half an hour and the face looks incredibly fresh. I, as a person who is used to sharing beauty secrets, joyfully answered the question: “Have you done anything with your skin lately?” That this is a wonderful nicotinic acid.

ANOTHER OPINION

badstepa777 0 0 0% I wrote about this nicotinic acid! and so a month later! everything went away for me! after taking it for 10 days! but I still have 2 months to do it! the actions are such that when we drink it, blood flow is obtained, the face should turn red! long-standing acne suppressed! but the doctor said to take it strictly with food! 10 days before today! take 1 tablet 3 times a day STRICTLY WITH MEAL! drink these 10 days! then break! calculate when you will start there! and so in 10 days you start taking! 3 months in total! It turns out 3 times in 3 months!

What are nicotinic acid injections for?

with diabetes

Nicotinic acid (vitamin B3) is part of a substance called "glucose tolerance factor" (GTF) that plays an important role in regulating insulin and blood sugar levels. In studies conducted with insulin-dependent diabetics, the additional intake of nicotinic acid allowed the complete cessation of insulin injections in 66% of cases. Let me clarify that these people were all diabetic adults whose need for insulin exceeded their body's ability to produce it; therefore, they were forced to inject themselves and thus inject additional insulin into the body in order to control blood sugar levels; they were not diabetics from childhood, whose body produces very little or no insulin. Recommendations: If you are an adult diabetic on insulin, start taking nicotinic acid (as nicotinamide) 500 mg three to six times a day (for a total of 1.5 to 3 g per day) and carefully monitor your sugar levels in the blood, slowly reduce the dose of insulin, but always under the supervision of the attending physician. If you take insulin intermittently, you can increase your carbohydrate (glucose) tolerance by taking nicotinic acid 500 mg once or twice a day. Caution: In some people, nicotinic acid causes flushing of the face. Read the article about this vitamin and get to know what side effects you may encounter if you start taking it, and how it interacts with other drugs and products. http://vitaminas.ru/diabet0.html

when removing freckles

Nicotinic acid has the ability to reduce the sensitivity of the skin to sunlight. Ascorbic acid is taken 1.0-1.5 g three times a day before meals daily for 2-3 weeks, and nicotinic acid (vitamin PP) - 0.01 g 3 times a day after meals, also for 2 -3 weeks. There is a week break after each course. There are 2-3 courses in total. http://www.medaest.ru/state/4/

from redheads

Vitamin PP (nicotinic acid) when administered intravenously improves the condition of inflamed, acne-prone skin. However, intravenous injections are not the most convenient way to take medications at home. Therefore, try taking this vitamin by mouth at 100-250 mg one to three times a day in order to get rid of skin inflammation. However, it must be remembered that one of the most common side effects of nicotinic acid is reddening of the skin. If, after taking the vitamin, the reddening of the skin increases, and the blood pressure and pulse rate increase, stop taking it. Start with a dose of 100 mg once a day. Stick to this dose for two to three weeks and watch your body's response to the vitamin. Then increase the number of single doses to two, and then up to three times a day at weekly intervals. If you still do not see any result (and there is no reddening of the skin), increase the single dose to 250 mg, and the number of doses at first to two, and by lot, if necessary, up to three times a day. http://briut.pochta.org/bk4.htm

Nicotinic acid is a vitamin PP.

Vitamin PP is a component of the B-complex that is critical for energy production and well-being on many levels, especially for heart health and optimal circulation. It is involved in more than fifty reactions, during which sugar and fat are converted into energy. It is also essential for amino acid metabolism and is involved in the conversion of fats into substances called eicosanoids, hormone-like agents that control our body's metabolic pathways.