Gynecological suppositories terzhinan. Terzhinan vaginal tablets - official * instructions for use. Terzhinan: instructions for using candles

There are many good medicines in the world, but the vast majority of them have more or less pronounced restrictions for taking, contraindications, and side effects. To the greatest extent, this applies to the means used inside. But local preparations are not without drawbacks - for example, among suppositories for the treatment of inflammatory processes in gynecology, it is not easy to choose a medicine that can be advised in almost all cases without fear of consequences. Terzhinan, which doctors often prescribe to their patients, meets the highest reliability criteria. Why is he so good?

The action of terzhinan

Terzhinan vaginal tablets, produced by the French pharmaceutical company Laboratoires Bouchara-Recordati, contain several antimicrobial components.

Tinidazole affects the so-called anaerobes - bacteria that live in anoxic conditions. This substance copes with many pathogens, including difficult to eradicate Trichomonas, for the sake of getting rid of which earlier patients were supposed to drink unsafe metronidazole.

The next antibacterial agent - neomycin - covers the remaining spectrum of pathogenic bacteria, which makes the drug effective for any non-specific cause of infection, including infection with mixed flora.

Eliminates colonies of fungi, prednisolone suppresses inflammation, relieves swelling and itching. Also, the product is supplemented with clove and geranium oils, which have an antiseptic and anti-inflammatory effect, and also have a restorative effect on the mucous membrane.

When and how to apply the medicine

The drug is effective:

- with vulvovaginitis, vaginitis and colpitis of non-specific origin, including those that appeared after an exacerbation of genitourinary infections;

- to prevent infection before operations, childbirth, medical procedures (cauterization of the neck, setting the intrauterine device).

Evaluating the results of using the drug from a medical point of view, we can say that terzhinan is really effective both as a means of prevention and as a drug for the treatment of inflammation. Most patients describe its action as good, excellent, or nothing more, nothing less, excellent. Of course, it is also captivating that there are practically no prohibitions on the use of terzhinan: the drug acts exclusively locally, so patients may not be afraid of side effects associated with the penetration of its components into the blood.

It is very simple to treat with this remedy, you need to inject 1 tablet into the vagina every night for 10 days (as prescribed by the doctor - longer) every night. Before this procedure, the tablet should be held in water for half a minute so that it becomes softer and can dissolve, and after it you should lie down for several minutes.

Terzhinan during pregnancy

This remedy causes women much less concern than or even completely safe. Among a fairly large selection, it is often preferred to everyone else. And rightly so: the drug has something to “please” patients who have reason to fear for their own and not only their health.

So, the benefits of terzhinan for pregnant women are as follows:

- it does not accumulate in the body and does not cause effects on the child. Having established its low absorption, scientists were even “too lazy” to conduct pharmacokinetic studies, that is, to study its chemical transformations inside the body: it was not possible to find significant traces of the drug in the blood.

- its efficiency is close to 100%. Some women have difficulty choosing a remedy for "difficult" germs such as Trichomonas. But terzhinan works on the widest possible spectrum. Its component tinidazole, a safe “relative” of the dangerous metronidazole, significantly expands the range of therapeutic action of the drug, but it does not penetrate the mother’s body and does not pass through the placenta to the child.

- In the West, studies have been conducted that study the tolerability and effect of the drug in pregnant women at different times. In 2004, similar tests were carried out in our country, and twice as many patients participated in them than in Europe. Based on our results, it was included in the national guidelines for the treatment of urinary tract infections in pregnant women. Focusing on maximum safety, in Russia it is advised to use it from the second trimester - which is unusual, given that abroad it is used throughout the entire period.

The most frequent questions of patients

• When using the drug the next day, a slight burning sensation appeared. How to evaluate it?

In rare cases, transient discomfort may occur at the beginning of treatment with terzhinan. It will disappear in 2-3 days.

• The course is scheduled for 10 days, but in its second half, menstruation should begin. Should I stop treatment?

Not worth it, you need to continue therapy for the required time.

• Along with inflammation, the doctor found erosion and prescribed local treatment for it. Is it possible to use terzhinan together with sea buckthorn suppositories?

It is possible, the components of terzhinan do not interact with other drugs. But, if possible, it is desirable to divide the use of different means by 1-2 hours.

• After treatment with terzhinan, there was a delay in menstruation. Is it somehow related to the drug?

Terzhinan does not contain hormonal components, so it cannot affect the menstrual cycle, you need to look for other causes of the violation.

• There was vulvovaginitis, a course of treatment with terzhinan was carried out. The drug helped, but after a short time the symptoms reappeared. And this is not the first time ... What to do?

If a similar situation is created, then the infection occurs again. It is advisable to examine and treat the sexual partner, for this he should contact a urologist.

Perhaps, the use of terzhinan does not need further explanation. The main thing you need to know is that it is one of the safest and preferred treatments for gynecological problems. However, if you have any other questions, contact your doctor - he will definitely clarify the points of interest for you.

Some of the women from time to time are faced with such an unpleasant phenomenon as genital infections. They harm the general health of a woman, and also disrupt the rhythm of their usual and fulfilling life. In the prevailing cases of this kind of infectious diseases require an integrated approach, for which today such a drug as Terzhinan (Terzhinan, Tergynan) is very actively used. This remedy is available directly in the form of suppositories, as well as tablets for vaginal use. Produced by the French company Laboratories Bouchara-Recordati (Laboratoires Bouchara-Recordati).

Instructions for use Terzhinan

The drug, produced in the form of tablets and suppositories, is intended for the treatment of many diseases in women. As a rule, one candle is prescribed per day, which is recommended to be kept in water for about 30 seconds before use.

The drug, regardless of the form of release, is recommended to be administered before falling asleep, so that during prolonged sleep it has a longer effect. If the suppository must be applied during the daytime, then after the procedure it is recommended to lie down for at least 15 minutes. Sometimes treatment may involve the simultaneous use of both tablets and suppositories.

The course of treatment with the drug, as a rule, is 10 days. With complex mycoses, therapy should be extended up to 20 days. The drug can be used even during menstruation.

Tablets, like Terzhinan suppositories, are inserted into the vagina. No more than 1 tablet can be used per day, which is administered immediately before bedtime. This form of release of the drug is also suitable for the rehabilitation of the vagina before childbirth, abortion and before surgical operations in the vaginal area. For this, 1 tablet of the drug must be administered 2 hours before the procedure.

Among other things, the tablets of this drug are well suited for men who also have thrush. However, for some, this form of the drug turns out to be completely inconvenient to use - in such cases, attention should be paid to analogues produced in the form of an ointment or cream.

Terzhinan in the form of candles

Suppositories are a more common dosage form of the drug, when compared directly with tablets. They are intended for topical vaginal use. With the help of the described remedy, you can get rid of not only candidiasis, but also many other problems - Trichomonas, bacterial infections and inflammation processes. Due to this, candles are used for many diseases of the female reproductive system. In addition, Terzhinan in the form of suppositories acts quite gently, due to which the vaginal microflora remains unchanged. It should be noted that some drugs of similar action do not differ in this feature, and after their use, the microflora in the vagina is somewhat disturbed.

When a woman bears a child, she is very susceptible to the appearance of all kinds of diseases, including in the genitals. The use of the drug during pregnancy is not prohibited, however, it must occur under the strict supervision of a gynecologist. The most dangerous is the use of suppositories directly in the first trimester, but during the second and third there is no such restriction. Most often, Terzhinan is used during pregnancy to treat vaginitis, which is characterized by the parallel appearance of inflammatory processes on soft tissues, as well as bacteria and fungi.

It should be noted that when using the drug during pregnancy, you can not be afraid that it will harm the unborn child. It does not affect the fetus, and also cannot cause an overdose.

Terzhinan in the form of tablets

In addition to candles, the antifungal agent is also available in tablet form. Tablets for ease of use have an oblong shape, it is difficult to confuse them with another medicine, since there is a letter "T" on both sides.

The drug is available in a carton box, and the tablets themselves are contained in an aluminum blister (6 pieces).

Just like a suppository, the tablet should be held in a glass of water for 30 seconds before administration - so its action will begin much faster. The drug in the presented dosage form should be used at bedtime.

The described tablets are approved for use even during pregnancy and lactation.

Indications for Terzhinan's use

Tergynan- This is a drug that has a fairly wide spectrum of action. Therefore, it is very often prescribed for such diseases:

• Inflammatory processes in the vagina, the main cause of which is Trichomonas;
• Thrush, which has absolutely any stage;
• Vaginitis of bacterial origin;
• Mixed vaginitis;
• Mycoses;
• Colpitis;
• Sanitation of the vagina;
• Prevention of inflammatory diseases after childbirth, abortion and diagnostic manipulations.

Terzhinan is not suitable for the treatment of cystitis.

Price Terzhinan

Terzhinan is a rather expensive drug that can be bought at any pharmacy. It must be said that different forms of release of the drug have different costs, which must be taken into account directly during the selection and purchase of funds.

The purchase of Terzhinan should be carried out only after this drug is prescribed by a doctor based on the diagnosis. Otherwise, you can make a waste if, for example, the patient makes the wrong diagnosis on his own (some people self-medicate due to the lack of opportunity to visit a doctor).

Terzhinan's analogs

Many patients prefer to choose an analogue of Terzhinan - more affordable from a financial point of view, however, no less effective. Terzhinan can be called a unique drug, which is facilitated by all its components. Therefore, this remedy has no direct analogues, however, it is possible to choose a medicine that is close in action, which contains components identical to the original.

Most often, instead of Terzhinan, such means are chosen:

• Polygynax (Polygynax). This is a very effective drug, which is the closest substitute for Terzhinan. Polygynax has practically no side effects, and its composition is distinguished by several substances that are also found in the original product. The main difference of this drug is that it does not contain such a substance as ternidazole. Therefore, Polygynax is not suitable for the treatment of such an ailment of the female genital organs as trichomonas colpitis. Also Macedonian scientists Goran D, Vesna A, Adela S, Biljana TK, Snezana M in 2004 found out that Polygynax is effective for the treatment of fungal (fungal) vaginitis.
• Pimafucin. It refers directly to antifungal agents that are used to treat a variety of diseases. Pimafucin is convenient in that it is produced in several dosage forms at once - suppositories, ointment and tablets. The advantage of this antifungal drug is that during therapy with its use, you can not give up sexual activity. Sometimes patients complain about the occurrence of Pimafucin side effects such as burning, nausea and vomiting (they usually appear in the first days of treatment).
• Meratin Combi (Meratin Combi). It has a pronounced therapeutic effect, which manifests itself within a short time. The active ingredients are ornidazole (ornidazol), as well as neomycin sulfate, nystatin and prednisolone. In addition to antimicrobial, Meratin Combi has a corticosteroid and antiseptic effect. It comes directly in the form of vaginal tablets, which are effective in treating the predominant percentage of vaginitis. Due to the special composition, this remedy is often used directly for the sanitation of the vagina, which is performed before an abortion or childbirth. If we talk about such a detail as the cost of Meratin Combi, then it practically does not differ from Terzhinan. This substitute is highly not recommended for use in combination with other drugs, and especially with hormonal drugs.
• Clotrimazole. The tool is of synthetic origin and successfully fights against fungal diseases of the vagina. Clotrimazole has practically no side effects, with the exception of non-serious allergic manifestations. The drug has some contraindications, one of which is early pregnancy.

It should be noted that some Terzhinan substitutes are more effective. This can be explained by the fact that they have a much greater aggressiveness, and, accordingly, the likelihood of adverse reactions. It is for this reason that it is not recommended to replace the drug without the knowledge of your gynecologist.

Evidence of effectiveness, opinions of medical scientists

In the article by Moroz Vladimir Anatolyevich from the National Pharmaceutical University (Kharkiv), published in the scientific and practical journal “Dermatovenereology. Cosmetology. Sexopathology ”(2010), it is indicated that in certain nosologies the effectiveness of Terzhinan is 94.4%. In addition, the medical scientist writes that this combo has all the properties of 5-nitroimidazoles, but has no contraindications for topical use, since it does not have bioavailability in this case. This is the key "highlight" of the combination drug ternidazole-neomycin-nystatin (in detail the four components are disclosed below). The agent has a synergistic antimicrobial, antiprotozoal and fungicidal effect, without leading to a violation of the quantitative and qualitative composition of the normal vaginal biota in general. The use of Terzhinan is regulated, among other things, by orders of the Ministry of Health of Ukraine No. 286 of 06/07/2004 and No. 96 of 12/27/2007.

Pharmacologists Vitaly Iosifovich Mamchur (MD) and Sergey Nikolaevich Dronov (MD) in an article in the journal "Medical Aspects of Women's Health" (2015) describe some of the advantages of the combo remedy: compact elongated-flattened the form of a tablet that increases the area of ​​contact with the mucosa; smooth glossy surface and rounded edges that prevent irritation; preventing the growth of fungi, in particular, as a result of irrational antibiotic therapy; greater compliance (voluntary adherence to the prescribed regimen); the presence of 4 basic substances in the composition, which prevents polypharmacy (drug load).

Iraida Stepanovna Sidorova and Ekaterina Igorevna Borovkova in an article in a magazine
Russian Bulletin of an Obstetrician-Gynecologist (2007) conducted an experiment comparing Terzhinan, Neo-Penotran, Dalacin and Betadine®. Terzhinan provided a 98% cure rate along with Neo-Penotran. It also distinguished itself by the most prompt action, a positive effect on microcirculation.

Savicheva Alevtina Mikhailovna, Spasmodova Elena Vladimirovna in 2017 ("Journal of Obstetrics and Women's Diseases") conducted an in vitro test of the terzhinan agent on microorganisms such as Candida spp., Enterobacteriaceae, Atopobium vaginae, etc. The drug showed high efficiency against the dominant part of microbes.

Savicheva Alevtina Mikhailovna, Zakharevich Natalya Nikolaevna, Mikhnina E.A. from the Research Institute of Obstetrics and Gynecology. Otta, St. Petersburg, determined the effectiveness of the combo agent in 93.8% and 100% in vaginal candidiasis for non-pregnant and pregnant women, respectively.

In addition, on the Internet you can find a brochure of the Bouchara-Recordati Laboratories (Laboratoires Bouchara-Recordati), containing the results of Terzhinan's research by a number of scientists, including Novikova S.V., Levashova I.I., Logutova L.S., Leush S.S., Dzyubanchuk T.V., Dubossarskoy Z.M., Kokhanevich E.V., Konoplyanko V.V. etc.

Also, the study of the agent was carried out by Kalugina L.V., Tatarchuk T.F., Shakalo I.N., German D.G., Kuznetsova A.V., Kalugina L.V., Lipova E.V., Khrzayan R.S. ., Kuznetsova A.N., Illarionova E.A., Iskra A.I., Belousov E.A., Belousova O.V., Petrenko S.Yu., Popkova S.M. Dobrovolskaya L.M., Chichul N.S. Therefore, it can be considered highly studied.

Composition of Terzhinan

The effectiveness of the drug is achieved due to its special composition, which includes three antibiotics at once. This applies to any form of drug release. More specifically, the drug contains four of the following components:

• Ternidazole (Ternidazole, C7H12ClN3O3). This is an antibiotic of synthetic origin, which represents a group of nitroimidazoles. It is a derivative of imidazole. Effective only when applied topically. Ternidazole successfully fights various representatives of bacteria, in particular Gardnerella vaginalis, as well as protozoa.
• Neomycin (Neomycin, C23H46N6O13). It is a complex antibacterial substance and aminoglycoside, which has a bactericidal effect. It was discovered back in 1949 in the laboratory of the Jewish-Ukrainian-American biochemist and inventor Selman Abraham Waksman. This antibiotic fights staphylococci, streptococci and other infections in a short time, while it is powerless in the fight against fungi.
• Nystatin (C47H75NO17). It was discovered in 1950 by chemists Rachel Fuller Brown and Elizabeth Lee Hazen. It is also an antibiotic that fights fungi. It is the nystatin agent that is responsible for the treatment of genital candidiasis. It refers directly to polyene antibiotics, which means that nystatin is able to somewhat increase the overall permeability of those cells that are harmful.
• Prednisolone (C21H28O5). This substance is an analogue of hydrocortisone. It was discovered in the mid-fifties of the last century in the course of chemical experiments with Corynebacterium simplex (removal of the acetyl group). It is an effective hormone that is directly responsible for reducing inflammation during topical use. In addition, prednisone also performs an anti-allergic function.

Depending on the form of release of the drug, it also has auxiliary components that give the drug the form of a tablet / suppository.

Thanks to this composition, the cure of a disease occurs quite quickly. At the same time, the integrity of the vaginal mucosa does not become impaired, as well as pH.

Application features

Terzhinan is contraindicated in the first trimester of pregnancy, and its use is also prohibited at the age of less than 16 years. During the use of this drug, you should completely stop sexual activity. The main reason for this need is the likelihood of the destruction of the condom under the action of one of the components of the drug (nystatin).

Diseases such as vaginitis and trichomoniasis require simultaneous treatment not only for women, but also for men. The fact is that if one of the partners does not undergo the necessary course of treatment, then the other will definitely become infected again.

One of the possible side effects of the drug is dizziness. It is for this reason that it should not be used by those persons whose work is directly related to the management of road transport or other mechanism.

Patients who have other chronic diseases should carefully monitor their health during treatment with Terzhinan. The presence of such diseases provides for a fairly frequent delivery of the necessary tests and special studies. This applies to such diseases:

• High blood pressure;
• Tuberculosis;
• Osteoporosis;
• Diabetes mellitus of any type;
• heart or liver failure;
• Epilepsy;
• myopathy;
• Glaucoma.

An effective remedy for thrush is available in tablet form. The drug is injected into the woman's vagina and with regular use contributes to a complete recovery.

Elongated tablets have a beige tint and a special marking: the letter T on each side of the tablet. You can purchase this remedy in packs of 6 or 10 candles each.

As part of the candle Terzhinan have the following healing substances:

• ternidazole, which has a trichomonacid effect;
• neomycin, well overcoming the cell membrane of bacteria;
• prednisolone medicinal product;
• nystatin, which has an antifungal effect;
• flower oils cloves and fragrant geraniums.

With indications for the use of Terzhinan suppositories, doctors pay attention to the need to quickly resolve gynecological problems that have arisen.

The essential oils that make up the drug contribute to the rapid dissolution of the tablet and rapid penetration into the mucous membranes affected by bacteria.

Among the auxiliary components it is worth noting: starch, silicon dioxide, magnesium, lactose and a little purified water.

Indications for the use of vaginal tablets

Among the indications for the use of Terzhinan suppositories, gynecologists note infectious diseases that lead to inflammation of the vagina due to the sensitivity of the body to the effects of harmful bacteria.

The following types of vaginitis are treated with candles:

• bacterial vaginitis, which appears under the influence of staphylococcus, proteus, dangerous shigella, E. coli or infectious Trichomonas;
• fungal type of vaginitis caused by the presence of Candida yeast-like fungi in the body;
• vaginitis, in which the mixed flora of the vagina is characteristic.

It is important to remember that in addition to drug treatment, it is possible to carry out effective prevention of vaginitis.

1. Terzhinan in suppositories is indicated for use before certain types of surgical interventions.
2. Before a planned termination of pregnancy or childbirth.
3. Before and after interventions involving the establishment of an intrauterine device.
4. Before and after treatment of erosions of the vaginal mucosa.
5. Before diagnostic hysterography.
6. Before various manipulations involving the penetration of medical instruments into the vagina.

The spectrum of action of candles Terzhinan

The spectrum of action of the drug is quite wide. It is recommended to be used both as the main treatment component and for preventive purposes.

Instructions and application features

do not use more than one tablet within 24 hours.

For treatment to be effective, the following guidelines must be followed:

1. Before using the tablets, you need to wash the perineal area well. using a special tool that does not contribute to the appearance of irritation on the sensitive mucosa.
2. Wash your hands well and wipe them with an antiseptic lotion. If it is impossible to thoroughly wash your hands, you should use gloves to insert the tablet into the vagina.
3. Remove the candle from the package and place in a small container. with purified water for half a minute. This is done to dissolve the top layer of the drug and enhance its effectiveness.
4. There are prescriptions of experienced gynecologists who It is recommended to administer the drug in the supine position. It is not convenient for all women to do this in this position, and therefore you can enter the pill in any comfortable position, and then immediately lie down on a bed or sofa.
5. Lie in this position for at least 20 minutes. During this time, the drug will have time to dissolve inside the vagina and begin to affect its flora. If there is a need to lead an active lifestyle after the administration of the drug, this can be done after the time indicated above.

Contraindications to the appointment of Terzhinan

Candles Terzhinan indications for use have practically no contraindications. You need to be careful only if the body is intolerant to the components that make up the drug. If negative reactions are detected, treatment should be stopped and the drug should be replaced with its analogue.

Possible side effects of Terzhinan suppositories

Side effects when using suppositories are extremely rare.. This is possible only with a certain intolerance to the substances that make up Terzhinan.

The drug is so safe and does not harm the body that, with special indications, it is recommended to use it during pregnancy.

With intolerance to the components, a woman may experience slight itching or redness of the vaginal mucosa.

Is it possible to continue therapy with the onset of menstruation

It is important to remember that Terzhinan candles indications for use do not exclude the use of the drug during the menstrual cycle. Gynecologists do not advise using Terzhinan, provided that the woman feels significant discomfort during the administration and action of the medication.

Is it possible to use suppositories during pregnancy and lactation

The use of the drug according to its instructions during pregnancy is not excluded, but possible only under the supervision of a treating specialist.

At the same time, you need to know that tablets are not recommended for use during the 1st trimester. Candles are used in the 2nd and 3rd trimesters with identified inflammatory processes that affect the vaginal mucosa.

The drug is also used during lactation. The ingress of active substances into breast milk is excluded.

Storage conditions and shelf life

The drug is stored at an air temperature not exceeding 25ºС. Candles must be used within 3 years from the date of manufacture.

Analogues of vaginal suppositories Terzhinan

Effective drug Terzhinan has no absolute analogues. The spectrum of action of the drug is so wide that not all recognized analogues can cope with infections of the genital tract, which are treated with Terzhinan.

Despite this, the price of the drug is quite high compared to some analogues, and therefore, sometimes women can choose the latter.

Among the drugs that can replace Terzhinan, the following agents can be used:

1. Meratin combi- the active ingredients of the drug are nystatin and prednisolone. It is used for the treatment of vaginitis of various etiologies, sanitation of the vagina before childbirth and various surgical interventions.
2. Quite often in gynecological practice, the drug is used Neotrizol. It is recommended for use in bacterial-based vaginitis, Trichomonas, before and after cauterization of erosion that occurs on the cervix.
3. In an effective solution to the problem of thrush has long established itself positively Flucostat.
4. Has a wider spectrum of action compared to Terzhinan Pimafucin. They treat vulvovaginitis and damage to the body by various fungi. It is distributed for the treatment of not only gynecological problems, but also lesions of the digestive tract and skin integuments.
5. One of the analogues is Polygynax. It helps to eliminate itching and has an antimicrobial effect on the vaginal flora.
6. Not bad eliminates thrush drug clotrimazole. Available in the form of suppositories, as well as ointments and tablets. It has a pronounced antifungal effect on the affected mucous membranes.

Prices for candles Terzhinan

The drug Terzhinan is considered a rather expensive remedy for thrush. Some analogues are distinguished by a lower price. But thanks to good therapeutic actions, the purchase of this drug is always justified.

You can buy candles at an average price of 360-390 rubles per package with 6 tablets. 10 pieces of healing candles cost about 420-450 rubles.

On the Internet, you can find a lot of positive feedback from patients who cured thrush using Terzhinan. Among the main advantages note ease of use and rapid effective action of the drug.

The drug is highly praised by young mothers who are faced with an unpleasant disease during pregnancy. Thrush often occurs during the period of bearing a baby; it can be caused by a serious hormonal change in the body of a future mother.

Terzhinan is recognized as an effective drug that does not have negative effects on the body, and quickly eliminates the unpleasant symptoms of the disease. Be healthy!

Useful video materials on the use of Terzhinan suppositories for thrush:

Indications and contraindications for the use of Terzhinan:

Detailed instructions for the use of candles Terzhinan:

The answer to the question: is it possible to use vaginal suppositories on critical days:

Suppositories "Terzhinan" are combined drugs that have an antifungal, antibacterial, antiprotozoal and anti-inflammatory effect. This drug is widely used in gynecology for various infectious and inflammatory diseases of the reproductive system in women. What are the indications for use and analogues of the "Terzhinan" candle?

Compound

Suppositories "Terzhinan" have a cream color, oblong shape. They include several main active trace elements, their concentration in one candle is:

1. Neomycin - 0.1 grams.
2. Ternidazole - 0.2 grams.
3. Nystatin - 100,000 international units.
4. Prednisolone - 0.003 grams.

Candles are packaged in strips of six and ten pieces. There is only one strip in the package.

Pharmacological actions

Candles "Terzhinan" refer to combined medicines, the therapeutic effects of which are due to the main substances that make up the structure of the drug:

1. Neomycin is a broad-spectrum antimicrobial agent that belongs to the group of aminoglycosides and has a bactericidal effect.
2. Nystatin, a compound that is considered an antifungal antibacterial agent, has activity against yeast-like fungi of the genus Candida.
3. Prednisolone, a chemical derivative of the hormone hydrocortisone, has a strong anti-inflammatory effect by lowering the content of pro-inflammatory mediators that are produced by immunocompetent cells at the source of inflammation.

After intravaginal administration of the "Terzhinan" suppository, the active trace elements of the drug are absorbed in the mucous membrane, where they have a therapeutic effect. They are practically not absorbed into the general circulation.

Indications

The main medical indications for the use of Terzhinan suppositories are inflammatory processes in the vaginal mucosa caused by various infectious pathogens:

1. Colpitis is an inflammatory process of the mucous membrane of the vaginal cavity.
2. Trichomoniasis of the vagina is one of the most common sexually transmitted diseases, which is characterized by lesions in women of the vagina and urethra.

Is it possible to put candles "Terzhinan" from thrush?

The drug is widely used for candidal vaginitis - a fungal infection of the mucous membrane of the vagina and the vaginal part of the cervix.

In addition, the drug is widely used for the anti-inflammatory treatment of vaginitis of mixed etiology.

What are Terzhinan candles for? They are used prophylactically to prevent vaginitis. The indication for the use of Terzhinan suppositories is the implementation of gynecological operations, they are used before childbirth, abortion, as well as before the installation of intrauterine devices, hysterography (performed using an X-ray unit).

Is it possible to put candles "Terzhinan" for pregnant women?

Some future mothers are afraid to use such vaginal suppositories, as they contain an antibacterial agent. But according to many doctors, the medicine has only a local effect, not being absorbed into the general bloodstream, therefore it has no detrimental effect on the baby and its development.

The drug can be used at any stage of pregnancy and during breastfeeding, as due to the local action, its particles do not enter the milk.

According to the instructions, Terzhinan suppositories during pregnancy are prescribed in situations where there are signs of the disease, as well as to prevent them.

Contraindications

The only main prohibition on the use of Terzhinan suppositories is considered to be individual intolerance to the active ingredients of the drug, as well as any of the additional components of the drug. Before starting therapy with this medicine, it is necessary to exclude the presence of contraindications.

How to use candles correctly?

According to the instructions for use, "Terzhinan" suppositories in gynecology are intended for intravaginal use in women. They are inserted into the vagina in a horizontal position of the body once a day, usually at night. Before use, you need to hold the "Terzhinan" candle in water for twenty to thirty seconds for the subsequent dissolution of its shell into the vagina.

After the introduction of the suppository, in order to exclude the release of the active substances of the drug from the vaginal cavity, it is necessary to remain in a supine position for ten to fifteen minutes. The duration of treatment with candles is on average ten days.

What are Terzhinan candles used for? For preventive purposes, the drug is recommended to be used for six days. If necessary, in a situation of detecting a fungal infection, a medical specialist can prescribe suppositories for twenty days.

Peculiarities

According to the instructions for the use of Terzhinan suppositories in gynecology, it is known that several features of their use must be taken into account before starting the course. During the treatment of vaginitis in women, it is necessary to temporarily limit intimacy.

When diagnosing trichomoniasis, one should undergo a diagnosis, as well as, if necessary, treatment of the sexual partner. The active trace elements of the drug do not affect the structures of the central nervous system and the activity of the cerebral cortex. In pharmacies, suppositories "Terzhinan" are dispensed according to a doctor's prescription.

Overdose

Due to the low degree of absorption of the active microelements of Terzhinan suppositories into the general bloodstream, the likelihood of developing poisoning is considered low. If necessary, treatment is symptomatic.

Side effects

If the Terzhinan suppositories are used incorrectly, local negative reactions may occur, which include burning or itching in the female genital area, which usually manifests itself at the beginning of treatment and disappears on its own, without requiring cessation of therapy. In rare situations, local allergic reactions may occur, according to the instructions for use.

Analogues of candles "Terzhinan"

The drug has certain substitutes similar, both in composition and in the spectrum of action:

1. "Nystatin".
2. "Elzhina".
3. "Ecofucin".
4. "Hexicon".
5. "Pimafucin".
6. Synthomycin.
7. "Acilact".
8. "Clotrimazole".

"Elzhina"

The drug is a Russian generic. "Elzhina" effectively eliminates vaginitis of bacterial etiology:

1. Vulvovaginal mycoses (inflammatory lesions of the perineum, internal membranes of the vulva, vagina, urethra).
2. Candidiasis (diseases of the mucous membranes, skin, internal organs caused by yeast-like fungi of the genus Candida).

This medical product should not be used by sensitive to the composition and underage girls. In addition, Elzhin should not be used by pregnant and lactating women.

Harmful side effects can include:

• swelling;
• rash on the skin of the body;
• dryness of the genitals.

According to many responses, the drug is an effective remedy that is used to eliminate bacterial vaginitis, candidiasis and other vaginal inflammations. Patients note that the medication instantly eliminates burning, swelling and pain. But there are also reviews that indicate the appearance of severe burning and itching after the use of suppositories.

"Ecofucin"

Another medicine of domestic production, which is less common in pharmacies than other medicines. Ecofucin is recommended against candidiasis and various kinds of inflammatory processes in the vagina provoked by infection.

You can not use the drug for people who have problems with the absorption of its composition. The instructions for use note that during treatment, a woman can have sex. But it is recommended to visit a medical specialist to carry out a medical examination of a sexual partner. This is due to the possibility of his developing candidal diseases. During the use of suppositories in the vagina, mild itching may occur.

"Hexicon"

The drug has a more extensive list of indications. It is prescribed to prevent the following ailments:

1. Gonorrhea.
2. Chlamydia.
3. Genital herpes.
4. syphilitic disease.

And also these suppositories are used by gynecologists to prepare for an abortion or childbirth. It is effective in the treatment of inflammation of the vaginal mucosa of various origin and course.

"Hexicon" is prohibited for people with poor absorption of its active and additional components.

As a rule, side effects occur after the suppository has been inserted into the vagina. Allergic reactions are less common:

• rash;
• hives;
• redness of the skin.

"Pimafucin"

Country of origin - Italy. It is necessary to use the drug in the presence of the following diseases and conditions:

• vaginitis;
• vulvitis.

"Pimafucin" is contraindicated for people with hypersensitivity to the constituent components of the medical product. The main difference between the drug is the admission to treatment for women who are expecting a baby and while breastfeeding.

The patient may experience the following adverse reactions:

• rash;
• burning in the vagina.

What are the candles "Terzhinan" and "Pimafutsin" used for? The second drug is a polyene antibacterial agent from the group of macrolides with an extensive spectrum of action. All suppositories show increased activity against bacteria and fungi. Getting directly into the pathological environment, the active substance adversely affects its membranes, preventing further reproduction.

The drug has a pharmacological effect in relation to the sources of the disease, which are sensitive to natamycin. Even with prolonged use, the drug does not cause addiction and withdrawal syndrome.

"Syntomycin"

Russian-made drug. "Synthomycin" qualitatively fights colpitis, as well as cervicitis. In addition, it does not allow the appearance of other diseases of the female reproductive system that are inflammatory in nature. The drug is used for the implementation of gynecological measures:

• installation of a spiral in the uterus;
• preparatory stage of childbirth;
• artificial termination of pregnancy.

The drug differs markedly from other previously considered medications and a voluminous list of contraindications for admission. They concern those patients who do not tolerate its composition, have severe kidney and liver diseases. The drug is not recommended for people under the age of eighteen and who have not begun sexual activity. Women during pregnancy and breastfeeding are allowed the drug.

Analogs have more undesirable effects: ailments that are associated with the hematopoietic system, dermatological diseases, an increase in the area affected by the fungus. It is important to note that the sexual partner of a girl who uses Synthomycin can also suffer.

"Acilact"

What are the candles "Terzhinan" and "Acilact" used for? They well eliminate vaginal dysbacteriosis and other inflammations that affect the reproductive system of the female body. "Acilact" is used in preparation for gynecological surgical interventions to prevent complications.

It is necessary to highlight the absence of prohibitions on the use. But in the presence of vulvovaginal candidiasis, the medicine cannot be used.

After the intravaginal administration of the "Acilact" suppository, the bacteria spread in a thin layer on the mucous membrane, then they begin to multiply, gradually eliminating pathogenic microorganisms. They do not enter the general circulation.

In addition, "Acilact" is used for prophylactic purposes to prevent purulent complications that may occur after surgery, as well as difficult childbirth, abortion or hysteroscopy, curettage of the uterine fundus. The purpose of "Acilact" in the prophylactic use of the drug is considered to be prolonged antibiotic therapy, after which the number of bacterial cells decreases.

"Clotrimazole"

The drug is considered one of the inexpensive and effective domestic remedies. It is prescribed for candidiasis, vaginitis, as well as for prevention before performing operations in the field of gynecology.

"Clotrimazole" is contraindicated in patients who are sensitive to its composition, and in women who are in position.

The drug has a number of adverse reactions:

• pain in the lower parts of the stomach;
• rash;

The pharmacological effect of the drug is due to a violation of the formation of ergosterol, a component that is part of the membrane of fungal cells, as a result of which the permeability changes and further elimination of the cell is observed.

The drug exhibits high therapeutic activity in relation to dermatophytes, Candida yeast-like fungi, as well as mold fungi and pathogens of multi-colored lichen.

Storage conditions

The shelf life of Terzhinan suppositories is thirty-six months. The medication must be kept in a dark, dry, hard-to-reach place for children at an air temperature of no more than twenty-five degrees. The average price of candles varies from 350 to 500 rubles.

Opinions

You can find a huge number of positive reviews about the candles "Terzhinan", the patients in them tell that vaginal suppositories helped to eliminate serious gynecological diseases. Many women consider Terzhinan candles to be good and effective.

The main advantage of the drug is the availability and ease of use of suppositories, as well as women note the low price and normal tolerance by the body. In rare situations, drug therapy entailed the appearance of negative effects.

As a remedy for candidiasis and reducing secretions, Terzhinan suppositories are also widely used. Women of childbearing age use the drug at home, quickly resume the biocenosis of the vagina.

The representatives of the fair half, who used "Terzhinan" during pregnancy and breastfeeding, confirm in their responses the high effectiveness of the drug. Compared with other drugs, these suppositories had the best therapeutic effect.

Negative responses to suppositories are associated with increased sensitivity of individual patients to the composition of the medication. In addition, some women fix spotting that appears after Terzhinan candles. But medical professionals do not see a connection between bleeding and the use of suppositories.

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

In addition, Terzhinan is used to prevent vaginitis before gynecological surgical interventions (for example, "cauterization of cervical erosion", etc.), childbirth, abortion, installation of an intrauterine device and other manipulations carried out through the vagina.

Forms of release, composition and names of Terzhinan

Since drugs intended for insertion into the vagina are most often produced in the form of suppositories, Terzhinan may be mistakenly called candles Terzhinan. However, this is not correct, since the drug is available in the form of tablets. But it should be borne in mind that when someone says "Terzhinan candles", he means exactly the pills.

In addition, the drug is often called "Terzhinan 10" or "Terzhinan 6", where the number after the commercial name indicates the number of tablets in the package. Such names are not official, but are used by doctors, pharmacists and patients very often, and therefore are considered generally accepted. Therefore, using such common clichés, you can not worry that a person will be misunderstood.

The composition of Terzhinan tablets as active ingredients includes the following substances:

• Ternidazole - 200 mg;
• Neomycin sulfate - 100 mg (65,000 IU);
• Nystatin - 100,000 IU;
• Prednisolone sodium metasulfobenzoate - 4.7 mg, which corresponds to 3 mg of pure prednisolone;
• Geranium and clove oil - 1.2 g.

Terzhinan tablets contain the following substances as auxiliary components:

• Wheat starch;
• Colloidal silicon dioxide anhydrous;
• Sodium starch glycolate (type A);
• magnesium stearate;
• lactose monohydrate;
• Purified water (distilled, deionized, sterile).

Therapeutic effects of the drug

• Antibacterial action, which consists in the destruction of pathogenic and opportunistic bacteria (staphylococci, streptococci, gardnerella, etc.), provoking infectious and inflammatory processes in the vagina (colpitis);
• Anti-inflammatory effect, which consists in the rapid suppression of the inflammatory process in the vagina, provoked by any reason;
• Antifungal action, consists in the destruction of various fungi and the elimination of thrush;
• Antiprotozoal action consists in the destruction of pathogenic protozoa, such as chlamydia, Trichomonas, etc.

Ternidazole is an antifungal agent from the imidazole group, which stops the synthesis of lipids necessary for the construction of fungal cell walls. As a result, the cell membrane of fungi loses its properties, its configuration is disturbed, and it ceases to perform the necessary functions, as a result of which the microorganism dies. In addition, Ternidazole has a detrimental effect on trichomonas and gardnerella.

Neomycin sulfate is a broad-spectrum antibiotic of the aminoglycoside group, which has a detrimental effect on staphylococci (Staphylococcus spp.), Escherichia coli (Escherichia coli), Shigella (Shigella spp.) and Proteus (Proteus spp.), which are often the causative agents of nonspecific colpitis, vulvovaginitis or bacterial vaginosis. Microbial resistance to neomycin develops very slowly and rarely, so it is effective in almost all cases. In relation to various varieties of streptococci, neomycin is ineffective.

Nystatin is an antifungal antibiotic of the polyene group, which effectively destroys fungi of the genus Candida and, accordingly, cures thrush. Nystatin has been used for a long time and successfully, but despite this fact, the resistance of fungi to the antibiotic is practically absent.

Prednisolone is a glucocorticoid hormone derived from hydrocortisone and has a powerful anti-inflammatory effect. Prednisolone suppresses any inflammatory reaction, regardless of the nature of the causes that provoked it, therefore, in combination with antifungal, antibacterial and antiprotozoal agents, it quickly eliminates colpitis and vulvovaginitis of any etiology.

In addition, prednisolone has antiallergic and antiexudative effects. Therefore, under the influence of this component, women do not develop allergic reactions and edema stops.

Terzhinan - indications for use

So, Terzhinan tablets are shown for the treatment of vaginitis in the following cases:

• Bacterial vaginitis caused by Staphylococcus aureus, Proteus, Shigella, Escherichia coli, or Trichomonas;
• Complex therapy of colpitis provoked by chlamydia;
• Fungal vaginitis, provoked by yeast-like fungi Candida;
• Vaginitis caused by mixed flora, that is, simultaneously bacteria, fungi, trichomonas or gardnerella in various combinations.

• Before planned gynecological operations;
• Before childbirth or abortion;
• Before and after the installation of the intrauterine device;
• Before and after diathermocoagulation ("cauterization"), laser or chemical treatment of cervical erosion;
• Before hysterography or hysterosalpingography;
• Before any medical manipulations related to the introduction of any objects, instruments or doctor's hands into the vagina.

Terzhinan - instructions for use

General provisions

For treatment and prevention, it is necessary to administer one tablet once a day for the period of time prescribed by the doctor.

The tablet must be removed from the package immediately before use and inserted into the vagina as soon as possible, otherwise it may begin to soften and melt. A soft pill is much more difficult to properly insert into the vagina. To remove Terzhinan from the package, the foil must be torn along the length of the tablet or cut with scissors.

Terzhinan should always be administered with freshly washed hands with soap or with sterile surgical gloves. Do not handle with dirty hands. Moreover, hands that have not been washed for an hour are considered dirty, even if the woman was at home or in a relatively clean room.

Before the introduction of the Terzhinan tablet, it is recommended to wash your hands with soap - solid or liquid, and not use various commercially available lotions, waters, foaming formulations, emulsions and other products designed to remove contaminants from the skin of the hands. The only product that can be used to wash and sanitize hands before inserting pills into the vagina is antiseptic or antibacterial liquids.

In addition, it is necessary to avoid touching the anus with your fingers during the insertion of the tablet into the vagina, as this can lead to additional infection.

If part of the course of treatment with Terzhinan tablets falls on the period of menstrual bleeding, then it should not be interrupted. In other words, tablets must continue to be inserted into the vagina during menstrual bleeding, since their effectiveness is not reduced. But during menstruation, you should especially carefully observe the rules of hygiene when administering tablets.

If a woman has been diagnosed with vaginitis, then it is recommended to undergo a course of therapy not only for her, but also for her sexual partner. This recommendation should be considered mandatory in the case of trichomoniasis. In other situations, the treatment of the sexual partner is advisory.

During the entire period of therapy, it is necessary to refrain from sexual intercourse and not to use lubricants, lubricants, gels, ointments and any other means intended for insertion into the vagina, since they can completely neutralize the therapeutic effect of Terzhinan.

How to administer Terzhinan vaginally?

First, before the introduction of the tablet, you should wash the external genital organs and the perineum, including the anus, with warm water and soap. It is not recommended to use any gels or other hygiene products for washing. Then you need to wash your hands also with soap or treat them with an antiseptic liquid. If for some reason it is impossible to wash your hands, then you should put on sterile surgical gloves, which are sold in pharmacies.

After that, the tablet is removed from the package and dipped in a cup of clean, cool boiled water for 20-30 seconds, so that the top layer dissolves a little, and the drug begins to act immediately.

The tablet is removed from the cup and taken in a comfortable position for administration. At this point, you should dwell in more detail, since the instructions for use indicate that you need to administer the tablet in the supine position. However, it is not convenient for all women to administer the drug while lying on their backs, since the tablet is quite small and difficult to push into the collapsed vagina. Therefore, doctors recommend administering the drug in the position in which it is most convenient to do this, but in the immediate vicinity of the bed or sofa, on which it will be necessary to lie down a bit after the manipulation.

The most convenient for the introduction of Terzhinan tablets are the following positions:
1. Squatting with knees wide apart.
2. Standing, with one leg raised and resting on a chair or other elevation.
3. Lying on your back with knees and hips bent and legs drawn to the stomach.

Having chosen the optimal position, it is necessary with the fingers of a non-working hand (left for right-handers and right for left-handers) to gently part the labia to the sides and expose the entrance to the vagina. Then, with the index finger of the working hand, push the tablet deeply forward until it stops advancing.

After that, the finger must be removed from the vagina and, making a minimum of movements, lie on your back on a bed or sofa. In this position, you should lie down for 10-20 minutes so that the tablet completely dissolves and the active substances begin to be absorbed into the cells of the vaginal mucosa.

After 10 - 20 minutes, you can get up, put on your underpants, putting a panty liner on them, as discharge may appear, and go about your business.

How long does the treatment take?

Application of Terzhinan during the day

That is, Terzhinan tablets can be inserted into the vagina during the day, in the morning, and in the early evening, etc. But in this case, after the manipulation, you should definitely lie down for 10-20 minutes on your back on a flat surface, and only after that get up or sit down. Also, when Terzhinan tablets are administered during the daytime, daily pads should be used, since a small part of the melted medicine will flow out under the influence of gravity. In addition, it is morally and psychologically necessary to tune in to the fact that with the daily administration of Terzhinan tablets, it is necessary to increase the duration of therapy by about 1/4 - 1/3 in order to compensate for the leaked volume of the drug. That is, if a 10-day course of Terzhinan is prescribed, then with the introduction of tablets during the day, it should be increased to 12-13 days, etc.

After Terzhinan

In some women, Terzhinan causes severe itching, which they mistake for a recurrence of thrush. However, this drug is not able to provoke thrush, since it contains components that have a detrimental effect on fungi of the genus Candida, which are the causative agents of the disease. Therefore, the cause of itching and discharge during the use of Terzhinan are other factors.

So, normally, in the first days of treatment, tablets can really cause itching, which gradually decreases, and completely disappears by the end of therapy. If the itching does not decrease and does not disappear, then most likely this is a manifestation of an allergic reaction, which requires the abolition of Terzhinan.

After using Terzhinan, many doctors recommend putting down a course of any suppositories containing lactobacilli and bifidobacteria for the speedy restoration of microflora. Most often, candles Vagisan, Atsilakt, Bifidumbacterin and others are used for this purpose. Separately, it should be noted the drug Vagilak, which is a capsule for oral administration containing strains of lactobacilli that penetrate well from the intestine into the vagina and take root well in it. Also, to restore the microflora of the vagina after treatment with Terzhinan, you can take ordinary probiotics, since the normalization of the intestinal microflora will accelerate this process in the genitals.

Influence on the ability to control mechanisms

Overdose

Interaction with other drugs

Treatment with Terzhinan - effective regimens

So, for the relief of itching and the prevention of trovorous secretions similar to thrush that occur in the first days of Terzhinan's use, it is recommended to put down Pimafucin suppositories for 3 to 5 days before that. This tactic makes the use of Terzhinan comfortable and almost invisible.

To stop the discomfort that occurs after treatment with Terzhinan, which in most cases are due to the absence of normal vaginal microflora, since the pathological one was destroyed during therapy, and the normal one has not yet had time to settle, microsyringes with antiseptic Tantum Rose or probiotic preparations are used. Among probiotics, the most effective are Vagisan, Vagilak, Acipol and others.

Separately, it is worth noting Vagilak, which is a capsule for oral administration, which is very convenient, since you do not need to insert something into the vagina again. These capsules contain lactobacilli that can penetrate the vagina through the intestinal wall, quickly populate it and take root, due to which Vagilak quickly restores normal microflora.

Application for thrush

If this treatment regimen is followed, thrush is completely cured and its relapses do not bother the woman for several years.

Terzhinan during pregnancy and breastfeeding

From the second trimester of pregnancy and up to childbirth, Terzhinan can be used without fear, since during these periods of childbearing the drug is no longer able to have a negative effect on the fetus.

During breastfeeding, it is not recommended to use Terzhinan, however, if there are indications and a clear excess of benefits over risks, the drug is allowed to be used.

Side effects

• Feeling of itching, burning and irritation in the vagina;
• Allergic reactions (rash, urticaria, skin itching, etc.).

Contraindications for use

Tablets (candles) Terzhinan: release form, composition, indications, instructions for use, dosages, contraindications, side effects - video

Analogues

Terzhinan's analogues are the following drugs:

• Vagisept vaginal suppositories;
• Vagiferon vaginal suppositories;
• Gynomax vaginal suppositories;
• Ginalgin vaginal tablets;
• Giterna vaginal tablets;
• Klion-D 100 vaginal tablets;
• Clomegel gel vaginal;
• Metrogyl Plus vaginal gel;
• Metromicon-Neo vaginal suppositories;
• Neo-Penotran, Neo-Penotran forte and Neo-Penotran forte L vaginal suppositories;
• Polygynax vaginal capsules;
• Polygynax Virgo emulsion for insertion into the vagina;
• Elzhina vaginal tablets.

Cheaper analogues of Terzhinan

• Vagisept - 209 - 230 rubles;
• Ginalgin - 230 - 300 rubles;
• Clomegel - 60 - 120 rubles;
• Metromicon-Neo - 300 - 400 rubles for 14 tablets.

What is better than Terzhinan?

Terzhinan is an effective drug, well suited to many women, so it is considered a "good" remedy. If any woman at this particular moment did not fit the drug, then you will have to try using analogues. And the analogue that turns out to be the most suitable and effective, and will be the best for this particular woman at the current time.

According to the reviews of doctors and women, Vagisept, Polygynax, Gaynomax and Elzhina are good analogues of Terzhinan. Therefore, if Terzhinan for some reason did not suit the woman or was not effective enough, then it is recommended to try these drugs, which are highly likely to be better.