Ferrum lek chewable tablets instructions for use. Ferrum lek for injections - instructions for use. Injection

INSTRUCTIONS
on the medical use of a medicinal product

Read this leaflet carefully before you start using this medicine.
Keep the instructions, they may need to be repeated. If you have any questions, please contact your doctor. This medicine has been prescribed for you personally and should not be shared with others as it may harm them even if they have the same symptoms as you.

Registration number:

Trade name of the drug:

Ferrum Lek ® .

International non-proprietary name or grouping name:

Dosage form

Compound

1 chewable tablet contains:
Active substance: iron (III) polymaltose hydroxide 400 mg, in terms of iron - 100 mg.
Excipients: macrogol 6000 - 37.0 mg; aspartame - 1.5 mg; chocolate flavor - 0.6 mg; talc - 21.0 mg; dextrates - to obtain 730.0 mg.

Description

Round flat tablets of dark brown color with patches of light brown color, with a chamfer.

Pharmacotherapeutic group

ATX code: B03AB05.

Pharmacological properties

Indications for use

Contraindications for use

Carefully

No data.

Use during pregnancy and during breastfeeding

Dosage and administration

Inside, tablets can be chewed or swallowed whole. The drug is recommended to be taken during or immediately after a meal.
The daily dose can be divided into several doses.
Doses and duration of treatment depend on the degree of iron deficiency.
Latent iron deficiency
The duration of treatment is about 1-2 months.

Iron-deficiency anemia
The duration of treatment is about 3-5 months. After normalization of the hemoglobin concentration, you should continue taking the drug for several more weeks to replenish iron stores in the body.
Children over 12, adults and breastfeeding mothers
1-3 chewable tablets (100-300 mg) Ferrum Lek ® per day.
Pregnant women
Latent iron deficiency and prevention of iron deficiency
1 chewable tablet (100 mg) Ferrum Lek ® per day.
Iron-deficiency anemia
2-3 chewable tablets (200-300 mg) Ferrum Lek ® per day until the hemoglobin concentration returns to normal.
Thereafter, continue to take 1 chewable tablet daily at least until the end of pregnancy to replenish iron stores in the body.

Daily doses of the drug Ferrum Lek ® tablets for the prevention and treatment of iron deficiency in the body

Side effect

Ferrum Lek ® is generally well tolerated. Side effects are mostly mild and transient.
According to the World Health Organization (WHO), adverse reactions are classified according to their frequency of development as follows: very often (≥1/10), often (≥1/100,<1/10), нечасто (≥1/1000, <1/100), редко (≥1/10000, <1/1000) и очень редко (<1/10000); частота неизвестна – по имеющимся данным установить частоту возникновения не представлялось возможным.
Nervous System Disorders
infrequently: headache.
Gastrointestinal disorders
Often: change in the color of feces (due to the excretion of non-absorbed iron, has no clinical significance);
often: diarrhea, nausea, dyspepsia;
very rarely: pain in the abdomen, constipation, vomiting, discoloration of tooth enamel.
Skin and subcutaneous tissue disorders
very rarely: hives, rash, itching of the skin.
If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects that are not indicated in the instructions, tell your doctor about it.

Interaction with other drugs

Ferrum Lek ® contains complex-bound iron, which causes a low probability of ionic interactions with food components (oxalates, tannins, etc.), as well as with other drugs (eg, tetracyclines, antacids).
Interaction with other drugs or food has not been identified.
Simultaneous use with parenteral iron preparations and other oral iron (III) preparations of polymaltose hydroxide is not recommended due to a pronounced inhibition of the absorption of orally ingested iron.

special instructions

Influence on the ability to drive vehicles, mechanisms

Ferrum Lek ® does not affect the ability to drive a car and control mechanisms that require increased concentration.

Special precautions for the disposal of unused medicinal products

Not applicable.

Release form

Storage conditions

At a temperature not higher than 25°C.
Keep out of the reach of children.

Best before date

5 years.
Do not use the drug after the expiration date.

Holiday conditions

On prescription.

Manufacturer

Good day!

In this review, I will share my experience of using the iron-containing drug Ferrum Lek in ampoules for intramuscular injection. The injections were not so terrible, and the result was worth only a couple of bruises on the sirloin.

GENERAL INFORMATION

Number of ampoules: 5 items

Volume of 1 ampoule: 2 ml

Composition for 1 ampoule:

iron (III) in the form of a complex of iron (III) hydroxide with dextran-100 mg; water for injection - up to 2 ml.

Production: Slovenia

Vacation: on prescription

Place of purchase: pharmacy

Price: 1327 rub. + cost of syringes

DESCRIPTION

The packaging of the iron-containing preparation Ferrum Lek is a small square box of a typical color for this company.

Inside the box are the ampoules themselves in the amount five pieces (the contents of two ampoules at the time of photographing were already wandering inside my body), which are embedded in a substrate with individual cells. In this package, the ampoules are completely safe.

Instructions for use are also attached to the drug, which must be MANDATORY read before use. This is not the case when you should rely on "maybe", yes "I know everything"

This product contains iron

in the form of a complex compound of polyisomaltose hydroxide. The product is similar in its structural structure to the natural compound of the element, namely ferritin

I am not a doctor, so I will not succeed in explaining the mechanism of action of this complex in the right words. The only thing I understood is that thanks to this form, there is a rapid replenishment of iron stores in the body.

INDICATIONS FOR USE ✾ PURPOSE

General indications for the use of Ferrum Lek in ampoules:

latent type iron deficiency therapy; treatment of anemia due to iron deficiency; prevention of deficiency of this trace element during pregnancy; situations in which treatment with oral iron preparations is ineffective or not feasible, for example, for an injectable form

My testimony

Iron deficiency anemia has haunted me for many years. With varying success, I either normalize my hemoglobin level, or it rolls down again. Diagnosis is made and then removed. In one of my reviews, I already wrote about the Fenuls iron-containing drug (you can read it), with the help of which I try to maintain hemoglobin.

In the last six months, I somehow started the situation by stopping taking the above drug, and I was in no hurry to do a blood test either. But the circumstances developed in such a way that at the end of September I still had to run around to the doctors, and at the same time pass a bunch of tests.

As expected, hemoglobin levels were again below normal. The therapist, after seeing the results, shook his head and threatened with injections. Thought he was joking, but no. Despite the fact that the hemoglobin level was low, but far from critical, he prescribed me a five-day course of injections of Ferrum lek 50 mg, to quickly raise hemoglobin, and only then drink Fenyuls for two months, to accumulate iron reserves in the body.

Despite the fact that the instructions describe what dosage of Ferrum Lek is necessary for each specific case, only a doctor prescribes this drug, yes besides it is released by prescription. At the pharmacy they asked me for it, and they didn’t even want to sell it due to the lack of some kind of seal there. They also asked for the recipe at the clinic where I went to do them.

Ferrum Lek dosage calculation in ampoules:

APPLICATION FEATURES

The therapist immediately warned that injections should be done in a hospital if there is no health worker at home. Even the manual says:

This is due to the fact that the injection is given intramuscularly, i.e. in the buttock, and from improper administration, bruises that do not go away for a long time can form. In addition to the aesthetic side of the issue, iron preparations in such a concentration can cause unforeseen allergic reactions.

After listening to all this, I decided not to risk it and get injections at the nearest clinic. Of course, the prices are not encouraging: 200 rubles per injection. Thus, a thousand rubles for injections were added to the cost of the drug itself.

In addition to the drug itself, I needed to purchase syringes. Since the injection must be done deep into the muscle, the pharmacy gave me 5 ml syringes, they have just the right length of the needle. If you still decide to inject yourself, then consider this point.

Feelings during and after injection

I am not afraid of injections. Well, I’m not afraid, I don’t faint from the sight of a needle. This is a plus, because. I don’t shrink from fear, and the needle enters the target like clockwork

If you don't stress, then injection is completely painless . A couple of times I didn’t even realize that everything was already done. By the way, the Ferrum Lek injection itself is not done instantly, but the contents are injected slowly, about 1-2 minutes, although according to the instructions:

You get tired of standing for so long.

The injection site begins to ache half a minute after the injection of the drug, but not much, very tolerable. After 10-20 minutes, all discomfort disappears.

Side effects from the use of Ferrum Lek

The instruction warns of the following possible side effects:

Fortunately, I did not have any side effects from Ferrum Lek injections.. The only thing that still took place was the minimum bruises in the amount of 2 pieces and the size of a penny. At the time of writing the review, and this is 10 days after the last injection, the bruises have practically disappeared, but the injection site still hurts as you press on it.

How to Minimize Bruising and Speed ​​Up Healing

First of all, the likelihood of bruising depends on the correct administration of the drug and on the skill of the medical staff (if you do it in a hospital). If the injection is delivered as it should, then you can completely do without this side effect. But it is better to take the initiative in your own hands and take measures to prevent them.

Firstly, after the injection you need to move. Due to the fact that I did the injections outside the house, it worked out for me, 20 minutes of intense walking to the house.

Secondly, I used Troxevasin gel at the injection site. I smeared several times a day throughout the course, and after its completion, until the bruises almost completely disappear. You can use any absorbable ointment / gel.

RESULTS

A week after the completion of the five-day course, I went to take a blood test. The result pleased, the level of hemoglobin and other indicators improved. Hemoglobin slightly fell short of the norm, but it's not scary.

I note that a month passed between the two tests, during which a surgical intervention was performed in my body, which was accompanied by a certain blood loss. Consequently, the level of hemoglobin at the time of the appointment of Ferrum Lek injections was even lower than indicated in the analysis in the top photo.

Thus, Ferrum Lek managed to improve the performance in a short period of time, namely, in just 5 days. But it’s too early to relax, there are still 2 months of taking Fenyuls ahead.

CONCLUSIONS

Despite the fact that I was completely satisfied with the action of Ferrum Lek, one should not hope that he will solve the problem of iron deficiency anemia once and for all, because. since it has already appeared, then, most likely, it will periodically pop up as soon as you relax both in terms of nutrition and in terms of prevention.

Ferrum Lek injections are effective for quickly raising the level of hemoglobin, but for the accumulation of iron stores, it is necessary to take other forms of iron-containing preparations.

Once again, I would like to emphasize that you cannot prescribe injections to yourself. Only a doctor can determine whether you need them or not, and also accurately prescribe the dosage, because. An excess of iron is no less dangerous than its deficiency.

On my own behalf, I can only say that if you have iron deficiency anemia, or you are in the category of an increased risk of its development, then in addition to complete blood count, hand over a separate analysis on ferritin. Doctors in most cases do not prescribe this analysis, because. they don't do it for free. Even with good hemoglobin level, ferritin levels may be low, and this already indicates the development of iron deficiency anemia, and prophylaxis should already be prescribed.

The drug Ferrum Lek in ampoules for intramuscular injection I recommend.

Be healthy!

Thank you for stopping by

Preparation: FERRUM LEK®
The active substance of the drug: non appropriated
ATX encoding: B03AB
CFG: Antianemic drug
Registration number: P No. 012698/02
Date of registration: 06.04.07
The owner of the reg. Credit: VIFOR (International) Inc. (Switzerland)

Ferrum lek release form, drug packaging and composition.

Chewable tablets are dark brown, interspersed with light brown, round, flat, with a bevel.

1 tab.
iron hydroxide polymaltose
400 mg
in terms of iron
100 mg

Excipients: macrogol 6000, aspartame, chocolate flavor, talc, dextrates.

10 pieces. - strips (3) - packs of cardboard.

The syrup is clear and brown in color.

5 ml
iron(III) hydroxide polymaltose
200 mg
in terms of iron
50 mg

Excipients: sucrose, sorbitol (solution), methyl parahydroxybenzoate, propyl parahydroxybenzoate, ethanol, cream flavor, sodium hydroxide, water.

100 ml - dark glass bottles (1) complete with a measuring spoon - packs of cardboard.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action Ferrum lek

Antianemic drug. Ferrum Lek contains iron in the form of a complex compound of iron (III) hydroxide with polymaltose.

The molecular weight of the complex is about 50 kDa, so its diffusion through the gastrointestinal mucosa is 40 times slower than the diffusion of ferrous iron. The complex is stable and does not release iron ions under physiological conditions. The iron of the multinuclear active zones of the complex is bound into a structure similar to the structure of the natural iron compound, ferritin. Due to this similarity, the iron of this complex is absorbed only by active absorption. Iron-binding proteins located on the surface of the intestinal epithelium absorb iron (III) from the complex through competitive ligand exchange. Absorbed iron is mainly deposited in the liver, where it binds to ferritin. Later in the bone marrow, it is incorporated into hemoglobin. The complex of iron (III) hydroxide with polymaltose does not have the pro-oxidant properties inherent in iron (II) salts.

Pharmacokinetics of the drug.

Studies using the double isotope method (55Fe and 59Fe) have shown that iron absorption, measured by the level of hemoglobin in red blood cells, is inversely proportional to the dose taken (the higher the dose, the lower the absorption). There is a statistically negative correlation between the degree of iron deficiency and the amount of iron absorbed (the greater the iron deficiency, the better the absorption). To the greatest extent, iron is absorbed in the duodenum and jejunum. The remaining (unabsorbed) iron is excreted in the feces. Its excretion with exfoliating cells of the epithelium of the gastrointestinal tract and skin, as well as with sweat, bile and urine, is approximately 1 mg of iron / day. In women during menstruation, there is an additional loss of iron, which must be taken into account.

Indications for use:

Treatment of latent iron deficiency;

Treatment of iron deficiency anemia;

Prevention of iron deficiency during pregnancy.

Dosage and method of application of the drug.

The syrup can be mixed with fruit or vegetable juices or added to baby food. The measuring spoon enclosed in the package is used for precise dosing of the syrup.

Doses and duration of treatment depend on the degree of iron deficiency.

With iron deficiency anemia, the duration of treatment is about 3-5 months. After the normalization of hemoglobin levels, you should continue taking the drug for a few more weeks to replenish iron stores in the body.

Children under the age of 1 year are prescribed 2.5-5 ml (1/2-1 measuring spoon) of syrup / day.

Children aged 1 to 12 years - 5-10 ml (1-2 scoops) of syrup / day.

Children over 12 years old, adults and breastfeeding mothers - 1-3 tab. chewing or 10-30 ml (2-6 measuring spoons) of syrup / day.

Pregnant women are prescribed 2-3 tablets. chewing or 20-30 ml (4-6 measuring spoons) of syrup until the hemoglobin level normalizes. After that, you should continue to take 1 tab. chewable or 10 ml (2 scoops) syrup/day at least until the end of pregnancy to replenish iron stores in the body.

With latent iron deficiency, the duration of treatment is about 1-2 months.

Children aged 1 to 12 years - 2.5-5 ml (1/2-1 measuring spoon) of syrup / day.

Children over 12 years old, adults and breastfeeding mothers - 1 tab. chewing or 5-10 ml (1-2 measuring spoons) of syrup / day.

Pregnant women are prescribed 1 tab. chewing or 5-10 ml (1-2 measuring spoons) of syrup / day.

Daily doses of Ferrum Lek for the prevention and treatment of iron deficiency in the body
Age
Iron-deficiency anemia
Latent iron deficiency
Prevention of iron deficiency
Children under 1 year old
2.5-5 ml syrup (25-50 mg iron)
*
*
Children (1-12 years old)
5-10 ml (50-100 mg of iron)
2.5-5 ml (25-50 mg iron)
*
Children (>12 years), adults and nursing mothers
1-3 tab. chewable or 10-30 ml syrup (100-300 mg iron)

*
pregnant
2-3 tab. chewable or 20-30 ml syrup (200-300 mg iron)
1 tab. chewable or 10 ml syrup (100 mg iron)
1 tab. chewable or 5-10 ml syrup (50-100 mg iron)

* - due to the fact that this group of patients requires low doses of iron, it is not recommended in these cases to prescribe the drug in the form of tablets or syrup.

Side effects of Ferrum lek:

From the digestive system: very rarely - a feeling of heaviness in the epigastric region, nausea, constipation, diarrhea. When taking the drug, staining of feces in a dark color is noted, which is due to the excretion of non-absorbed iron and has no clinical significance.

The reported side effects were mostly mild and transient.

Contraindications to the drug:

Excess iron in the body (for example, hemochromatosis);

Iron utilization disorders (eg, anemia caused by lead intoxication, sideroahrestic anemia);

Anemia not associated with iron deficiency (for example, hemolytic anemia, megaloblastic anemia caused by a lack of cyanocobalamin);

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation.

In the course of controlled studies, when using the drug in the II and III trimesters of pregnancy, there was no negative effect on the body of the mother or fetus. No harmful effects on the fetus were found when using the drug in the first trimester of pregnancy.

Special instructions for use Ferrum lek.

Chewable tablets and syrup do not cause staining of tooth enamel.

When prescribing Ferrum Lek to patients with diabetes, it should be borne in mind that 1 tab. chewing and 1 ml of syrup contains 0.04 XE.

In cases of anemia caused by an infectious or malignant disease, iron accumulates in the reticuloendothelial system, from which it is mobilized and utilized only after the underlying disease has been cured.

Taking the drug does not affect the results of fecal occult blood tests (selective for hemoglobin).

Pediatric use

For children under the age of 12, due to the need to prescribe low doses of the drug, it is preferable to prescribe the drug in the form of a syrup.

Influence on the ability to drive vehicles and control mechanisms

Does not affect.

Drug overdose:

In cases of overdose of the drug Ferrum Lek for oral administration, no signs of intoxication or signs of excessive intake of iron into the body have been described so far, since iron from the active substance is not present in the gastrointestinal tract in free form and is not absorbed by passive diffusion.

Interaction Ferrum lek with other drugs.

No interaction with other drugs has been noted.

Conditions of sale in pharmacies.

The drug is dispensed by prescription.

The terms of the storage conditions of the drug Ferrum lek.

The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C. The shelf life of chewable tablets is 5 years, the shelf life of syrup is 3 years.

Active substance

Iron hydroxide polyisomaltose

Release form, composition and packaging

Solution for intramuscular injection brown, opaque, practically free of visible particles.

Excipients: sodium hydroxide, hydrochloric acid (concentrated), water for injection.

2 ml - ampoules (5) - blisters (1) - cardboard packs.
2 ml - ampoules (10) - blisters (5) - cardboard packs.

pharmachologic effect

Antianemic drug.

In the preparation, iron is in the form of a complex compound of iron (III) hydroxide polyisomaltose. This macromolecular complex is stable and does not release iron in the form of free ions. The complex is similar in structure to the natural iron compound - ferritin. Iron (III) hydroxide polyisomaltose does not have pro-oxidant properties that are inherent in iron (II) salts.

Iron, which is part of the drug, quickly compensates for the lack of this element in the body (including with iron deficiency), restores the level of hemoglobin (Hb).

When using the drug, there is a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, soreness and dryness of the skin) and laboratory symptoms of iron deficiency.

Pharmacokinetics

Suction

After the / m administration of the drug, iron quickly enters the bloodstream: 15% of the dose - after 15 minutes, 44% of the dose - after 30 minutes.

Iron in combination with transferrin is transferred to the cells of the body, where it is used for the synthesis of hemoglobin, myoglobin and some enzymes.

breeding

T 1/2 - 3-4 days The complex of iron (III) hydroxide polyisomaltose is quite large and therefore is not excreted through the kidneys, the compound is stable and does not emit iron ions under physiological conditions.

Indications

Treatment of all conditions of iron deficiency requiring rapid replenishment:

• severe iron deficiency due to blood loss;
• impaired absorption of iron in the intestine;
• conditions in which treatment with oral iron preparations is ineffective or not feasible.

Contraindications

• excess iron in the body (hemosiderosis, hemochromatosis);
• violations of the mechanisms of inclusion of iron in hemoglobin (anemia caused by lead, sideroahrestic anemia, thalassemia);
• anemia not associated with iron deficiency;
• Osler-Rendu-Weber syndrome;
• infectious diseases of the kidneys in the acute stage;
• uncontrolled hyperparathyroidism;
• decompensated;
• infectious hepatitis;
• I trimester of pregnancy;
• hypersensitivity to the components of the drug.

Carefully the drug should be used for bronchial asthma, chronic polyarthritis, cardiovascular insufficiency, low ability to bind iron and / or deficiency, in children under 4 months of age.

Dosage

The drug in the form of a solution can be administered only in / m. It is not allowed to / in the introduction of the drug!

Before the introduction of the first therapeutic dose, each patient should receive a test dose of 1/4-1/2 ampoules (25-50 mg of iron) for adult and 1/2 daily dose for children. In the absence of adverse reactions within 15 minutes after administration, the remainder of the initial daily dose is administered.

Doses of the drug Ferrum Lek are selected individually in accordance with the total iron deficiency, calculated according to the following formula:

Total iron deficiency (mg) = body weight (kg) × (estimated Hb level (g/L) - detected Hb (g/L)) × 0.24 + deposited iron (mg).

At body weight up to 35 kg: calculated level of Hb = 130 g/l, deposited iron = 15 mg/kg of body weight.

At body weight over 35 kg: calculated Hb level = 150 g/l, deposited iron = 500 mg.

Factor 0.24 = 0.0034 × 0.07 × 1000 (iron content in Hb = 0.34%, total blood volume = 7% of body weight, factor 1000 - conversion from g to mg).

Calculation of the total number of drug ampoules based on the detected hemoglobin level and body weight

If the total number of ampoules to be administered exceeds the maximum allowable daily dose, then the total number of ampoules should be divided by the required number of days. If 1-2 weeks after the start of treatment, hematological parameters do not improve, the diagnosis should be clarified again.

Calculation of the total dosage for replacement of iron due to blood loss

With a known amount of blood lost in / m, the introduction of 200 mg of iron (2 ampoules) leads to an increase in hemoglobin equivalent to 1 blood unit (400 ml with a hemoglobin content of 150 g / l).

Amount of iron to be replaced (mg) = number of blood units lost x 200 or number of ampoules needed = number of blood units lost x 2

With a known final level of hemoglobin, the above formula is used, taking into account that the deposited iron does not need to be replenished.

Amount of iron to be replaced (mg) = body weight (kg) × (calculated Hb level (g/L) - detected Hb level (g/L)) x 0.24

Usual doses of Ferrum Lek

Adults and elderly patients prescribe 100-200 mg (1-2 ampoules) depending on the level of hemoglobin; children- 3 mg / kg / day (0.06 ml / kg body weight / day).

The maximum daily dose for adults- 200 mg (2 ampoules); for children- 7 mg / kg / day (0.14 ml / kg body weight / day).

Rules for the administration of the drug

The drug is administered deeply intramuscularly alternately into the right and left buttocks.

In order to reduce pain and avoid skin staining, the following rules should be followed:

• the drug should be injected into the upper outer quadrant of the buttocks using a 5-6 cm long needle;
• before injection, after disinfection of the skin, the subcutaneous tissues should be moved down by 2 cm to prevent subsequent leakage of the drug;
• after the injection of the drug, the subcutaneous tissues should be released, and the injection site should be pressed and held in this position for 1 minute.

Before using the solution for intramuscular injection, the ampoules should be carefully examined. Only ampoules containing a homogeneous solution without sediment should be used. Solution for intramuscular injection should be used immediately after opening the ampoule.

Side effects

From the digestive system: nausea, vomiting.

From the side of the central nervous system:, dizziness.

Local reactions: with an incorrect technique for administering the drug, it is possible - skin staining, the appearance of soreness and an inflammatory reaction at the injection site.

Others: arterial hypotension, arthralgia, swollen lymph nodes, fever, malaise; extremely rarely - allergic or anaphylactic reactions.

Overdose

Symptoms: overdose of iron preparations can lead to acute iron overload and hemosiderosis.

Treatment: symptomatic therapy. As an antidote, slowly (15 mg/kg/h) deferoxamine is administered intravenously, depending on the severity of the overdose, but not more than 80 mg/kg/day. Hemodialysis is ineffective.

Today, blood diseases come out on top among all pathologies of the body. The most common of them is anemia, the causes of which are many: from bad habits, poor ecology to severe diseases of the bone marrow and other blood-forming organs. Everyone who is faced with the problem of anemia will look for effective means for themselves in order to say goodbye to this misfortune as soon as possible. In cases of iron deficiency anemia, Ferrum Lek is one of the priorities. “How to take the drug?”, “Can it be done with leukemia?”, “How long does the medicine work?” ‒ questions that have gained the most popularity on the forums among patients. Answers to them can be obtained by reading the instructions for the drug.

Iron is one of the most important trace elements, plays a leading role in the formation of hemoglobin, a protein involved in oxygen-carbon dioxide metabolism.

Iron deficiency leads to anemia, which leads to oxygen starvation of the body. Causes of anemia:

• poor nutrition;
• bad habits;
• passive lifestyle;
• diseases of the hematopoietic organs;
• leukemia;
• massive bleeding;
• focus of chronic inflammation.

Composition and forms of release

The active substance of the drug is trivalent iron. Among all the dosage forms of Ferrum Leka, there are three.

Solution for intramuscular injection

In each ampoule, the solution is 2 milliliters, which is equivalent to 100 mg of iron. Immediately after the injection, a depot of iron is created, which is released for several more days. Well suited for helping in critical conditions, especially if there are iron absorption disorders in the digestive tract. Despite this, this route of administration gives the greatest number of various complications. Each package contains 5 ampoules with injection solution.

Tablets

Syrup

One milliliter contains 5 mg of the active ingredient. The drug is produced in a dark bottle with a screw cap, packed in a cardboard box. Well suited for pediatric use, as well as for the treatment of patients who need to take less than 100 mg per day.

Forms for oral administration are more effective than injection, while they are also safer in relation to allergic manifestations. In most cases, especially after massive bleeding, for the speedy stabilization of the patient, the agent is immediately used both in injections and in tablets. This allows you to quickly form a depot of iron, which allows you to stabilize the indicators of hemoglobin, red blood cells. As the condition normalizes, they switch to a tablet form to consolidate the effect.

Analogues

If, for some reason, Ferrum Lek does not suit the patient and you have to choose another iron preparation, this will not be a big problem, since there are several similar equally effective remedies.

If you need to choose a substitute for intramuscular and intravenous administration, Maltofer, Dextrafer, Ferrolek are worthy analogues. As for syrup or tablets, Orofer, Ferumbo is well suited.

Pharmacological properties

The drug Ferrum Lek, regardless of the form of release, is intended for the treatment of iron deficiency anemia, it works due to the iron saccharate included in it. With its help, hemoglobin in the blood rises, signs of anemia disappear. In the forms for oral administration, the substance remained in its native state, and the injection solution contains dextran as an auxiliary agent, which allows the gland to enter the bloodstream immediately, bypassing the gastrointestinal tract.

According to the therapeutic effect, the varieties of forms do not differ; in all three cases, iron is absorbed equally well. The only difference is how quickly you need to get the desired result.

Indications for use

Ferrum Lek injections are prescribed for such conditions:

• anemia, which was provoked by massive blood loss;
• patient intolerance to excipients that make up oral preparations;
• inflammatory diseases of the mucosa of the digestive system, preventing the absorption of iron.

Indications for the use of Ferrum Leka for internal use are:

• prevention of anemia in children, pregnant women, during lactation;
• treatment of iron deficiency anemia of mild or latent form.

To understand which form of medication is best to use, you need to know exactly the level of iron deficiency. This indicator can be calculated using the following formula: body weight (kilograms) is multiplied by the difference between the hemoglobin norm and current indicators, multiplied again by 0.24. To this result, the amount of iron from the body's reserves is added (determined using a blood test for serum iron. If it drops below the norm, it can be judged that the reserves are depleted). With a mass of less than 35 kg, a hemoglobin indicator of 130 is taken as the norm, over this weight - 150.

Dosage and administration

Duration of treatment, doses of Ferrum Leka are adjusted individually, paying attention to the age of the patient, the severity of the disease. The effect of the treatment is equally good, regardless of which form of the drug the patient has chosen.

In the absence of malabsorption in the lumen of the digestive organs with anemia for children and adults, it is better to choose oral forms. They are also suitable for the treatment of pathology of any severity. Another great advantage of these drugs is that the iron that enters the intestines is released gradually, without having an aggressive effect on the body.

The drug in injections is used in the treatment of anemia caused by iron deficiency, when there is a disruption in the digestive system. To calculate the number of ampoules of solution needed for a course of treatment, you need to divide the total iron deficiency by one hundred.

The duration of Ferrum Lekom therapy is 4–5 months, of which 2–3 are spent on eliminating anemia and a few more to replenish iron stores.

How to take adults

Treatment of anemia in adults is carried out in various dosages, depending on the severity of the course of the disease.

For treatment, the daily dose is 200-300 mg, it must be divided into several doses, not more than 100 mg at a time. If the choice fell on the ampouled form, no more than 200 mg can be given per day, the medicine must be administered deep intramuscularly, adhering to all the rules of asepsis and antisepsis.

As a preventive measure, 1 tablet or 10 ml of syrup per day is used.

Use in children

From 1 year to 12 years, no more than 100 mg of the substance should be taken per day. For this category, tablets can already be used. For children weighing less than 35 kg, the daily dose is calculated individually, based on indicators of iron deficiency. For prevention, you need to take no more than 5 ml of syrup per day.

Use in pregnant and lactating

The drug Ferrum Lek is allowed to be taken with low hemoglobin during pregnancy and lactation. For treatment, you need to drink 2-3 tablets per day, for prevention - 1 tablet or 10 ml of syrup per day throughout pregnancy. Syrup and tablets can be taken in any trimester, injectable form only from 13 weeks.

For all categories of patients, it is recommended to divide the daily dose into several doses so that iron is supplied evenly, in small amounts. It is better to take the drug after a meal in order to avoid irritation of the mucosa of the digestive tract. You can not drink milk, tea, these products inactivate the effect of the drug, and the desired effects will not be obtained.

When not to apply

Contraindications for the use of Ferrum Leka of any dosage form are:

• anemia not associated with iron deficiency;
• allergies to the components of the product;
• inflammatory processes of the mucosa of the gastrointestinal tract (gastritis, enterocolitis, Crohn's disease).

Before starting treatment with this drug, it is necessary to do analyzes of the kidneys, thyroid gland, liver. The presence of hepatitis, cirrhosis, hyperthyroidism, acute infectious diseases of the kidneys in a patient does not allow the use of this medicine.

Side effects

As for side effects, Ferrum Lek's drugs rarely cause them, but they still exist, and they should be given due attention. While taking the drug, you may experience:

• heaviness, pain in the stomach;
• dyspeptic disorders;
• inflammation of the mucosa of the digestive tract;
• allergies;
• general malaise;
• fever.

When taking oral medications, stool turns black. Injection of Ferrum Leka can lead to induration at the injection site, pain.

Overdose

Cases of overdose occur most often with parenteral administration. During internal administration, exceeding the required dose is almost impossible, since excess iron is simply not absorbed into the intestines, but is excreted with feces. Overdose symptoms are:

• vomit;
• abdominal pain;
• gastrointestinal bleeding;
• weakness;
• dizziness;
• cardiopalmus;
• inhibition of the nervous system;
• convulsions;
• arthritis;
• myalgia.

Interaction with other drugs

Varieties of Ferrum Leka cannot be used simultaneously. Five days must be allowed between injection and internal administration. The use of ACE inhibitors together with iron significantly increase its absorption, possibly overdose symptoms.

Determination of the effectiveness of treatment

Treatment of iron deficiency anemia should be carried out under the control of laboratory blood parameters, namely general and biochemical analysis. To restore the level of ferritin and other blood parameters, the drug is taken for several more months.

Storage

Store Ferrum Lek at a temperature not exceeding 25C, in a dark place protected from light.

Price

The tablet form of Ferrum Leka costs 300-400 r, the price of syrup is 200 r, and the injection solution, 5 ampoules of 2 ml each, is 800-1000 r.