Tablets "Eufillin": instructions for use for cough, reviews. Eufillin in children is an unsafe drug for home use

An effective bronchodilator are injections and tablets "Eufillin". What helps this drug? The drug has vasodilating properties, improves blood circulation. Means "Eufillin" instructions for use recommend using for bronchitis, migraine, bronchial asthma.

Composition and form of release

Produced in the form of tablets and solution for injection. Tablets "Eufillin", from which the medicine helps with pulmonary pathology, contains an active element - aminophylline in a volume of 150 mg.

The concentration of the active substance in the solution for injection is 24 mg/ml. Sold in ampoules of 5 and 10 ml.

pharmachologic effect

The drug belongs to the category of xanthines. Tablets "Eufillin", from which the remedy helps to relieve spasms, expands the bronchi. The medicine improves the functions of the respiratory tract, ventilation is easy, saturates the blood with oxygen, removes carbon dioxide from it.

The instruction to the drug "Eufillin" indicates that it improves and stimulates the contractile activity of the heart muscle. The drug reduces the tone of the vessels of the kidneys, skin and brain, relaxes the walls of the veins and lowers the pressure in the pulmonary circulation. By improving blood flow to the kidneys, urine production and excretion are increased.

The drug inhibits platelet aggregation, thins the blood, improves its rheological properties. When taking, it must be borne in mind that Eufillin tablets increase the acidity of the stomach.

The drug has absolute bioavailability, when consumed with food, its absorption slows down a little. The active substance enters the mother's milk and passes through the placenta. Cleavage occurs in the liver, excreted from the body along with urine.

Injections, tablets "Eufillin": what helps the medicine

Indications for the use of the tablet form include:

• emphysema;
• bronchial asthma;
• obstructive bronchitis in a chronic form;
• paroxysmal apnea.

What injections "Eufillin" help?

The drug in ampoules is used for:

• cardiac asthma;
• migraine;
• broncho-obstructive syndrome;
• cerebrovascular insufficiency of the brain;
• left ventricular failure;
• hypertension in the pulmonary circle.

Contraindications

The instruction prohibits the use of "Euphyllin" for:

• epilepsy;
• hyperthyroidism;
• extrasystole;
• dysfunction of the kidneys and liver;
• diarrhea
• hypersensitivity to the drug "Eufillin", from which it can cause allergies;
• prostate adenoma;
• collapse.

Do not give Eufillin tablets to children under 6 years of age. The drug is not prescribed for acute heart attack, paroxysmal tachycardia, peptic ulcer.

The drug "Eufillin": instructions for use

Taking pills

Drink after meals with plenty of water. The dosage depends on the individual characteristics of the patients. If necessary, the volume of the drug is increased every 3 days until the desired result is achieved.

Tablets "Eufillin" for bronchitis are prescribed in a daily dosage of 0.45 - 0.90 mg with a possible increase to 1.2 g. Patients weighing more than 50 kg can be taken 4 times a day. The interval between primams is at least 6 hours.

With a body weight of adults less than 50 kg and in adolescence with children weighing 45-55 kg per day, from 0.45 to 0.6 mg is prescribed. For children from 6 to 17 years old with bronchitis, the dosage is calculated by weight of 13 mg per kg, as a standard they give 1 tablet three times a day.

With an exacerbation of chronic obstructive pulmonary disease, at the initial stage, 5-6 mg per kg for adults per day is indicated, the volume of the drug is gradually increased. In the absence of exacerbations, 6-8 mg per kg are prescribed, but not more than 400 mg per day. The indicated dosages should be divided by 3-4 times.

Eufillin injections: instructions for use

In difficult situations, when you need to immediately help the patient, adults are injected with a large dose of the solution into a vein. The dosage is 5.6 mg per kg of body weight. This volume is dripped for 30 minutes. The Eufillin dropper is prepared by combining 10-20 mg of the drug with 0.9% sodium chloride in a ratio of 1 to 1. The resulting composition is diluted with 250-500 ml of saline.

As a maintenance treatment, intravenous administration of the drug at a dosage of 0.9 mg per kg is indicated. A dropper is made for 1-3 hours. The maximum daily dosage for an adult is 0.5 ml per kg.

The use of the solution in pediatrics

Babies up to 3 months of age, the drug is injected into a vein at a dose of 30-60 mg per day. For other ages, the amount of the drug varies from 60 to 500 mg per day. Injections into a vein are done within 5 minutes. The drug is diluted in an aqueous solution of sodium chloride.

Intramuscularly for children, the drug is administered in an amount of 15 mg per kg of body weight. The duration of therapy takes no more than 2 weeks.

In the treatment of sleep apnea in infants under 12 months of age, the initial dosage is 5 mg per kg of body weight. The solution is administered through a nasogastric tube. To maintain the condition of the child, they switch to a two-time administration of 2 mg per kg. Therapy lasts up to several months.

electrophoresis

The drug "Eufillin" for electrophoresis is used for the treatment of osteochondrosis and arthrosis in adults. For children, the procedure is performed to reduce intracranial pressure, hypertonicity, and dysplasia.

The procedure is done on the cervical vertebrae, lumbar region. Due to the point action of the drug, electrophoresis does not cause side reactions. It is made for babies older than 30 days.

During the procedure, the specialist wets the gauze bandage in the solution, lays it on the affected area and connects the electrodes. For the penetration of the drug into the depths of the tissues, it is enough to perform electrophoresis for a quarter of an hour.

The therapeutic course is designed for 10 sessions. As a rule, adult patients and children tolerate this procedure well. Electrophoresis is unacceptable for neoplasms, skin pathologies, high blood pressure, heart failure, arrhythmias.

Side effects

The medicine "Eufillin", instructions and reviews say this, can cause negative reactions of the body. Side effects include:

• increased sweating;
• excitation;
• nausea;
• headache;
• diarrhea heartache.
• vomiting;
• insomnia;
• arrhythmias;
• heartburn;
• dizziness;
• pressure reduction;
• increased heart rate;
• allergy;
• stomach ache;
• tremor.

Analogues

An identical active substance contains such analogues of "Euphyllin", such as:

1. "Aminophylline-Eskom".
2. "Eufillin-Darnitsa", -Pharm.

Medicines have a similar effect:

1. "Neotheopack".
2. "Theophylline".
3. "Diprofillin".
4. "Theobromine".
5. "Theotard".

During pregnancy and breastfeeding

The medicine "Eufillin" during pregnancy is prescribed in exceptional cases. Indications for the drug in this period are placental insufficiency, edema and other threatening pathologies. After using the drug, expectant mothers experienced dizziness, palpitations. However, the medicine made them feel better. During lactation, the drug is not prescribed.

Price

In Moscow, you can buy Eufillin tablets at a price of 10, ampoules - 30 rubles. In Kyiv, the drug is sold for 12-30 hryvnia. Its price in Minsk reaches 0.01 - 1.38 bel. rubles, in Kazakhstan - 300 tenge.

Eufillin is referred to as a vasodilator, they are recommended in the treatment of bronchial diseases. This article is an instruction for the use of injectable ampoule in ampoules for non-specialists.

In contact with

Vacation form and composition

The drug is intended for oral and parenteral use. The pharmaceutical industry manufactures aminophylline for intramuscular injection, 1 ml, containing 240 mg of the active component of aminophylline, a xanthine derivative. The release form of intravenous aminophylline is ampoules of 5 or 10 cm3. The concentration of aminophylline is 10 times less than in the preparation for intramuscular use. The medication is packed in 2; 5; 10 pieces in a cardboard box. The kit includes original instructions and a device for opening ampoules.

Important! The medicine is produced in two varieties. For intramuscular injections, the drug is intended in ampoules containing 240 mg / g of aminophylline or 24%. The concentration of the active ingredient in the drug for intravenous use is 10 times lower.

Pharmacology and appointment

Eufillin dilates the bronchi, relieves spasms, stimulates the myocardium, thins the blood, has a diuretic effect.

The ability to increase the sensitivity threshold of the respiratory center to CO2 leads to an intensification of blood oxygen saturation. It is metabolized in the body and excreted in the urine.

Most often it is prescribed for bronchitis. In addition, the drug is used when the following situations occur:

• bronchial or cardiac asthma;
• migraine;
• pulmonary edema;
• chronic cough;
• apnea is short-term cessation of breathing. Snore.

Important! Eufillin relieves bronchial spasms, thins the blood, saturates it with oxygen, stimulates the activity of the respiratory center.

Application

This bronchodilator is administered in the following ways:

• intramuscularly;
• intravenously;
• using a probe;
• microclysters;
• electrophoresis;
• inhalation.

Intramuscular administration

Eufillin is administered intramuscularly in extraordinary cases. Injections are very painful, and the daily dose must be divided into 3-4 injections. The injection is made into the buttock with a thick needle at the rate of up to 1500 mg per day for an adult. Eufillin is used for children at the rate of 150 mg/10 kg body weight. The duration of the course of parenteral administration should not exceed 14 days.

Intravenous administration

In threatening situations, aminophylline is administered intravenously. Children up to three months are prescribed 30-60, older ones - 60-500 mg. The duration of the injection solution is 5±1 minute. In other cases practice drip administration. Fractional mixing is used. At the same time, 1-2 ten-ml ampoules are diluted with an equal amount of saline. 0.25–0.5 dm3 of isotonic sodium chloride is added to the resulting mixture. Drip administration lasts about half an hour.

Insertion with a probe

If a newborn has attacks of breath holding for a quarter of a minute or more with a slowdown in the rhythm of heart failure and blue skin, the solution is injected into the stomach through a nasal-gastric tube at the rate of 20 mg / 4 kg of weight.

it about 1 ml solution for intravenous use. If necessary, the procedures are repeated twice a day, using 0.4 ml of medication per four-kilogram baby.

At the discretion of the doctor, the course of therapy can last for weeks.

Microclysters

It is used in situations where it is necessary to continue treatment, taking tablets is contraindicated, and it is no longer possible to administer in ampoules. One or two containers of solution for intravenous or intramuscular administration are diluted with 20-30 cm3 of heated water and administered rectally after defecation. Shown 2-4-fold injection during the day. The method is applicable from the age of sixteen.

electrophoresis

Apply with osteochondrosis in adults, coxal joint dysplasia in children, and, if necessary, reduce intracranial pressure. The procedure is as follows:

• Moisten the gauze with the solution.
• Impose on a problematic place on the neck or lower back.
• Lead the electrodes and turn on the power. The procedure takes about a quarter of an hour.

The treatment course of electrophoresis is 10 sessions. The procedure is easily tolerated by children older than 4 weeks. However, there are contraindications - the presence of tumors, cardiac and skin pathologies, hypertension.

Inhalations

The medicine is used for relieving asthma attacks. The contents of one ampoule plus three with diphenhydramine are added to the container for aerosol spraying and adjusted with saline to 150 cm3. There is an expansion of the lumen of the bronchi, sputum is removed faster. The frequency of injections of the drug is determined by the pediatrician.

Euphyllin for children

Children under 13 weeks of age do not practice parenteral administration. Dosage by live weight is difficult, and non-compliance with it threatens with unpredictable results. Why does the doctor prescribe eufillin in ampoules? Most often from cough, bronchospasm, hypoxia, excessive intracranial pressure I.

The exact dosage for children is important, which depends more on age than weight. It is shown in the table.

*Where VN - age, weeks.

Older children, as well as adults, are prescribed 2–5 mg of the drug / kg of body weight, depending on the condition and the presence of other diseases. Elderly people, as well as people suffering from liver pathologies, prescribe the lowest dose, since the excretion of the drug from the body is inhibited. Smoking, on the contrary, accelerates the removal of the drug from the blood. Therefore, the maximum dosage is required in the treatment of diseases.

Eufillin in ampoules for adults

Ampoule administration for adults is indicated in acute situations when need to quickly relieve bronchospasm. Eufillin intramuscularly or intravenously is used for no more than 14 days, then it is necessary to switch to taking the drug in tablet form.

Eufillin for pregnant and lactating women

Aminophylline crosses the placental line, but it is relatively safe for the fetus, and for the mother it can cause toxicosis, manifested by vomiting, palpitations and discomfort.

Gynecologists prescribe a bronchodilator in case of edema or conditions that threaten the life of the mother.

The effect on infants up to 13 weeks of age is poorly understood, so the medicine should not be used by a nursing mother. Otherwise, you need to stop breastfeeding.

Side effects

Side effects when using eufillin in ampoules are accompanied by the following pathological symptoms:

• excitation;
• excessive sweating;
• nausea;
• headache;
• diarrhea;
• heartbeat;
• allergy;
• pressure surges;
• muscle trembling;
• polyuria.

Contraindications

Of course, there are contraindications for the use of the drug Eufillin. Cause appoint another type of therapy should be:

• epilepsy;
• pathology of the thyroid gland;
• diarrhea;
• BPH;
• heart or kidney pathologies;
• hypersensitivity to xanthine derivatives;
• old age;
• road transport management.

Analogues

The pharmaceutical industry manufactures the medicines listed below - analogues of the drug:

• Neotheopec;
• Theophylline;
• Aminophylline;
• Theobromine;
• Diprofillin;
• Theotard.

Restrictions

The drug is not prescribed to women during breastfeeding. During pregnancy, it is used when edema or placental insufficiency. After using the medicine, women experience palpitations and dizziness.

Eufillin is one of the most affordable drugs from the group of adenosinergic drugs. These are bronchodilator drugs that block the activity of enzymes involved in the regulation of the phosphodiester bond. The medicine is produced at pharmaceutical plants in Russia and the Republic of Belarus and is included in the list of vital medicines. The main indication for the appointment of "Euphyllin" is bronchial asthma, but the drug is widely used as part of complex treatment for other pathologies accompanied by broncho-obstructive syndrome.

The active substance of the drug - aminophylline - is a combination of ethylenediamine and theophylline. The substance has a pronounced stimulating effect on the respiratory center, relaxes the smooth muscles of the bronchial tree, eliminates spasms that cause breathing difficulties. Aminophylline can be considered an antagonist in relation to calcium ions, since it slows down their transportation through the calcium channels of cellular membrane structures. "Eufillin" helps to increase the amount of cyclic adenosine monophosphate and blocks adenosine receptors - cell surface purine receptors.

The medicine expands the peripheral vessels of the brain, renal and cardiac systems, and also increases the number of heart contractions and their strength. With prolonged use, it has a moderate diuretic effect, helps eliminate edema and remove excess fluid from soft tissues and subcutaneous fat.

Indications for the use of "Euphyllin" are:

• chronic obstructive pulmonary disease;
• bronchial asthma;
• progressive respiratory failure against the background of the absence of primary pathology of the bronchopulmonary system (Pickwick's syndrome);
• attacks of respiratory arrest at night, which can be caused by a lack of carbon dioxide in the circulating blood (night sleep apnea);
• destructive changes in the alveolar walls against the background of pathological expansion of the distal bronchioles (emphysema).

As part of combination therapy, the drug can be used for severe edematous syndrome, cerebrovascular accidents.

"Eufillin" in injections is indicated for increased blood pressure in the pulmonary arteries, left ventricular heart failure, migraine attacks of unknown etiology, and also for stopping attacks of cardiac-type asthma.

Release forms

"Eufillin" is produced in two four dosage forms, each of which has its own contraindications. For oral administration, Euphyllin tablets are prescribed containing 150 mg of the active ingredient, or film-coated tablets, which include 250 mg of aminophylline (this form is preferable for patients with diseases of the digestive system, as it reduces the load on the digestive tract).

If it is necessary to administer the drug by injection, a solution for intramuscular (240 mg of aminophylline in 1 ml of solution) or intravenous administration (24 mg of the active ingredient in 1 ml of the drug) is used.

Instructions for use

Tablets should be taken after meals with a sufficient amount of water (at least 70-100 ml of liquid per 1 tablet). The drug is well absorbed by the mucous membranes of the gastrointestinal tract and quickly binds to the protein components of the circulating blood plasma.

The solution can be used for intramuscular injection (deep into the gluteal muscle) or intravenous infusion. In acute conditions that threaten the patient's life, "Eufillin" is injected into a vein using an infusion pump. To prepare a composition for drip infusion, you need to mix 1-2 ampoules of the drug (20 ml) with the same amount of an aqueous solution of sodium chloride with a concentration of 0.9%. After that, the mixture is diluted in 250-500 ml of saline. The infusion should be carried out slowly (the minimum procedure time is 30 minutes).

Price

"Eufillin" is the most affordable drug in its pharmacological group. Its cost in online pharmacies is (average values ​​are indicated):

• tablets 150 mg (pack of 30 pieces) - from 4 to 14 rubles;
• ampoules 240 mg (pack of 10 ampoules) - from 54 to 66 rubles;
• 24 mg ampoules (pack of 10 ampoules) - from 24 to 85 rubles.

The final cost of the drug depends not only on the region of sale, but also on the manufacturer: a Russian-made drug will cost almost 2-3 times more than its Belarusian counterpart.

Analogues

"Eufillin" has many contraindications. Therefore, if necessary, the doctor can replace it with another medicine with similar medicinal properties. Replacement may also be required if you are allergic to aminophylline or have poor tolerance to the drug. The following are the popular analogues of "Euphyllin" and their cost.

• "Aminophylline"(58 rubles). The structural analogue of "Euphyllin", is available in the form of a solution for intravenous administration, tablets and rectal suppositories. It is used for the treatment of asthma, relief of bronchospasm, combined therapy of heart failure and conditions after cerebral infarction.
• "Teotard"(110-210 rubles). A drug from the group of adenosinergic drugs based on theophylline. Available in the form of capsules with a dosage of 200 mg and 350 mg. During treatment with theophylline preparations, it is necessary to control the level of the active substance in the blood serum, which should not be higher than 20 μg / ml, therefore "Teotard" is approved for use strictly on prescription.
• "Teopak"(130-250 rubles). An adenosinergic drug in the form of tablets and theophylline extended-release tablets. Available in three dosages: 100 mg. 200 mg and 300 mg.

Self-cessation of treatment with drugs from the group of adenosinergic drugs can lead to deadly conditions, so the cancellation of treatment should be carried out in several stages and monitored by the attending physician.

Contraindications

The use of "Euphyllin" is contraindicated in unstable blood pressure, arrhythmia, hemorrhagic stroke and some diseases of the gastrointestinal tract, for example, gastritis with high acidity, ulcerative lesions of the walls of the stomach and duodenum. Contraindications to therapy with this drug are seizures of epilepsy (including remission) and pathologies of the visual system, accompanied by retinal hemorrhage.

For some diseases, "Eufillin" can be used, but under strict medical supervision in a hospital setting. These states include:

• violation of blood flow in the coronary arteries;
• angina;
• necrotic lesions of myocardial fibers (infarction in a severe stage);
• prostate adenoma and prostatic hyperplasia;
• extrasystole of the right or left ventricle of the heart;
• insufficient production of thyroid hormones by the tissues of the thyroid gland;
• bleeding in the organs of the gastrointestinal tract;
• cardiomyopathy;
• thyrotoxicosis.

It is not allowed to take "Eufillin" with a long-lasting elevated body temperature (more than 38 °).

For children under three years of age, as well as for pregnant women, the drug can be prescribed if there are vital indications. In old age, treatment must be monitored by a doctor.

Dosage

The dosage regimen and the use of "Euphyllin" depends on the patient's age, body weight, underlying diagnosis and comorbidities. The recommended dosing regimen is shown in the table below.

The use of "eufillin" during pregnancy requires careful medical supervision in a hospital setting. Aminophylline rapidly accumulates in fetal tissues and can cause acute hypoxia and intrauterine death. For a mother, a violation of the dosing regimen can be dangerous by a violation of the heart and its stop, therefore it is strictly forbidden to take this drug on its own.

Side effects

Tolerability of the drug in different groups of patients can vary significantly. The active substance of the drug can cause serious side effects, therefore, during treatment, it is necessary to be guided by the prescription and recommendations of the doctor. Most often, side effects are manifested by the cardiovascular and nervous system. It can be:

• increased arousal and irritability;
• instability of the emotional state;
• headache;
• dizziness and fainting;
• sleep disorders;
• angina attacks;
• violation of the heart rhythm;
• tachycardia;
• pain syndrome in the left half of the heart, not associated with damage to its own vessels and arteries (cardialgia).

Common adverse reactions include digestive disorders: nausea, vomiting, heartburn. In some patients, peptic ulcer or gastritis may worsen. Some patients have increased sweating, an increase in daily diuresis, an increase in blood sugar, and pruritus. If a febrile syndrome occurs, it is necessary to stop treatment and consult a doctor.

When taking the drug in the third trimester of pregnancy, it is possible to increase the heart rate in the fetus, as well as the development of tachycardia in the newborn in the first 1-3 days after birth.

Compatibility

It is impossible to prescribe the drug simultaneously with antidiarrheal drugs and drugs from the sorbent group, since they reduce the absorption of aminophylline. In some cases, combining with other drugs can cause an increase in their side effects. These drugs include glucocorticosteroid hormones, drugs that excite the central nervous system and drugs for general anesthesia.

"Eufillin" increases the absorption of the active ingredients of beta-adrenergic stimulants and diuretics. When taken simultaneously with lithium preparations and adrenaline receptor blockers, it reduces their effectiveness.

Simultaneous use with drinks containing ethyl alcohol increases the absorption of aminophylline and neurotoxic effects.

Overdose

An overdose of "Eufillin" can lead to severe complications from the nervous and cardiovascular systems. To avoid serious consequences (among which the most severe is cardiac arrest), it is necessary to know the basics of emergency care, depending on what kind of symptoms the pathology manifested itself.

Regardless of the symptomatic manifestations, the patient must wash the stomach and give sorbents in a dosage appropriate for age. Continue further treatment according to the following scheme:

• with vomiting - "Metoclopramide" or "Ondansetron" intravenously;
• with convulsions - oxygen therapy;
• with seizures - "Diazepam" intravenously (no more than 10 mg).

A doctor's examination after an overdose of aminophylline preparations is required.

With a number of diseases of the respiratory system, Eufillin is prescribed, the indications for the use of this drug are as follows:

• respiratory failure due to bronchospasm;
• cerebrovascular accident.

The medicine is sold without a prescription in a pharmacy, but before using it is necessary to consult a doctor.

Eufillin has contraindications. The drug affects the tone of the blood vessels, so it can not be used for:

• heart failure and cardiac arrhythmias;
• angina pectoris and other forms of ischemia;
• epilepsy;
• peptic ulcer of the duodenum and stomach;
• dysfunction of the kidneys and liver;
• individual intolerance to aminophylline and theophylline;
• high blood pressure;
• gastritis;
• hemorrhagic stroke.

Eufillin is prescribed for children under 12 years of age only if the benefits of taking it outweigh the harm from the disease. Reception in children takes place under the supervision of a doctor. After 12 years, you can not take it simultaneously with Ephedrine and a number of other drugs, such as beta-blockers.

The following side effects are associated with exposure to blood vessels, which may occur while taking the drug:

• nausea and vomiting;
• headache and dizziness;
• tachycardia and other cardiac arrhythmias;
• anxiety, irritability, increased anxiety;
• cramps and muscle weakness;
• exacerbation of peptic ulcer;
• decrease in blood glucose.

Allergy to Eufillin and side effects are rare. In case of intolerance, a skin rash, urticaria appears. Eufillin has several forms of release, which differ in the speed of exposure. In some diseases of the internal organs, Eufillin is prescribed only when the potential benefit of taking the drug outweighs the likelihood of dangerous side effects.

With the following diseases, Eufillin can only be used under the supervision of the attending physician:

• prostate enlargement, including benign hyperplasia;
• atherosclerosis;
• hypothyroidism, thyrotoxicosis;
• prolonged fever, temperature rise over 38.5 °C;
• recent stomach or intestinal bleeding;
• gastroesophageal reflux;
• heart disease (myocardial infarction, coronary insufficiency, cardiomyopathy, ventricular extrasystole).

For immediate delivery of the drug to the blood, Eufillin is used in ampoules. Introduction is carried out:

• intravenously, solution 2.4%;
• intramuscularly, solution of 24%.

For a milder effect, Eufillin is used in 150 mg packaging tablets. There are 30 tablets in one blaster, while taking the tablet you need to drink clean drinking water, swallow it without chewing.

It is best to take the drug within an hour after a meal, but in an emergency it can be used at any time. If Eufillin is used to relieve allergic spasm of the respiratory tract, it is more profitable to drink a pill at night. It is at night that all manifestations of allergies are exacerbated.

In the treatment of what diseases is Eufillin used?

The range of application of Eufillin is quite wide, which is associated with its effect on the cardiovascular and respiratory systems. The effect of taking Eufillin:

• the smooth muscles of the respiratory tract relax, breathing becomes easier;
• the blood vessels of the lungs expand, more oxygen enters the blood;
• the work of the intercostal and respiratory muscles improves, muscle spasm is relieved;
• alveolar ventilation increases, bronchospasm is eliminated;
• coronary blood flow increases;
• blood pressure returns to normal, in the pulmonary circulation - decreases;
• the tone of the blood vessels of the brain, skin and kidneys is reduced;
• blood circulation in the tissues of the kidneys increases, the bile ducts expand;
• the formation of blood clots in the circulatory system is reduced;
• blood circulation in small blood vessels improves;
• red spots disappear from the skin of the patient's face and neck;
• due to blood saturation with oxygen, the amount of carbon dioxide decreases, the patient's condition normalizes in a short time.

In addition, Eufillin causes an increase in the acidity of gastric juice, which is why it is better to take it after meals. Indications for use of the drug - diseases of the respiratory system:

• severe spasm of the airways caused by an allergic reaction, bronchospasm;
• allergic reactions, which are expressed in difficulty breathing, bronchial asthma;
• Cheyne-Stokes reaction, systematized respiratory rhythm disorder;
• apnea, respiratory arrest.

Eufillin is also used for the treatment of cardiovascular diseases, indications for use in complex therapy:

• acute or chronic cerebrovascular insufficiency;
• cerebral vascular crisis;
• increased intracranial pressure;
• swelling of the brain.

In addition, Eufillin is used in the treatment of kidney failure and kidney edema. The use of Eufillin in conjunction with other drugs should be discussed with your doctor.

How to take Eufillin?

Reception can be one-time or last for a long time, from 1 week to several months. The dosage, frequency and duration of administration can only be correctly selected by the attending physician, who is aware of the entire clinical picture. A dropper with a solution of Eufillin is used to stop an attack of bronchospasm.

During drip administration, it is necessary to control the patient's blood pressure and heart rate. In outpatient treatment, Eufillin is prescribed in tablets.

Bronchopulmonary diseases are one of the most common not only among the adult population of the planet, but also among children of almost any age. The treatment of respiratory diseases has already formed into a whole branch of medicine. One of the favorite drugs with a constant effect is "Eufillin" (euphyllini). It has a pronounced activity, helps to fight pulmonary insufficiency, relieves cough. "Eufillin" is prescribed for children, observing some important precautions and restrictions.

The use of "Eufillin" has become widespread due to its pharmacokinetic properties. The active substance taken as a basis is theophylline. Known as aminophylline in the international pharmaceutical market. It has a pronounced bronchodilatory effect. What does it mean?

The main effect of the drug is that, through complex chemical interactions, the drug reduces the motor, contractile activity of smooth muscles.

Of course, this applies not only to the bronchi of different diameters, but also to the vessels, liver, uterus, and stomach. At the same time, eufillin increases the amount of blood that passes through the kidneys, which contributes to an increase in diuresis.

The action on the respiratory tract consists of the following steps:

A decrease in smooth muscle tone occurs due to a decrease in the flow of calcium ions through cell membranes due to blocking of purine receptors. Relaxation of the bronchi is necessary for the free discharge of sputum, improving respiratory activity.

The diaphragm begins to move actively, which is an auxiliary mechanism for ventilation of the respiratory system. At the same time, the contractile activity of the intercostal muscles increases. They contribute to the complete opening of the air passages.

Due to the activation of muscle fibers, indirect stimulation of the corresponding center in the brain occurs - the NPV increases.

"Eufillin" for children is also relevant as for adult patients, but its use is significantly limited due to some features of childhood.

The use of the drug is not limited to the treatment of diseases of the bronchi and lungs. "Eufillin" and its analogues are used in complex treatment due to the following properties:

• stimulate cardiac activity;
• reduce the tone of blood vessels that carry blood to the brain and kidneys;
• reduce the formation of blood clots in vessels of different calibers;
• improve the rheological properties of blood;
• increase the release of hydrochloric acid in the stomach.

It can be prescribed as a component of therapy for edematous syndrome of renal origin.

Drug analogues

A large number of medicines on the pharmaceutical market allows the patient and the doctor to choose exactly the drug that will have the maximum necessary effect. At the same time, it will be available for purchase at a price, and it will be easy to buy it in a particular locality. Many companies produce synthesized analogues of the original Euphyllin, based on are the same active ingredients.

In a pharmacy, you can find medicines with the active element "theophylline" in the base, but each has its own commercial name. For example, drugs produced in India, Slovenia, Ukraine are widely represented: Teopec, Teotard, Theophylline, Neophyllin, Unicontin. They are available in the form of tablets with different concentrations and dosages, solutions for injection.

Indications for the use of "Euphyllin" in children

In childhood, there are a number of serious restrictions on the use of "Eufillin" precisely because of such a diverse spectrum of influence. Children under three months of age are generally not subject to therapeutic exposure to this remedy. In the age interval between one and three years, it is preferable to use eufillin treatment in the form of inhalations. Babies under six years of age are prescribed electrophoresis with eufillin, older children are given the drug intravenously.

Any diseases of the respiratory system with a spastic component, cough, difficulty breathing are indications for the appointment of aminophylline:

• bronchitis with asthma-like attacks;
• obstructive bronchitis;
• emphysema;
• acute laryngitis with spastic attacks;
• swelling of the airways at any level;
• bronchial asthma;
• pneumonia.

In addition to the above diagnoses, it is used as a palliative in the treatment of cerebrovascular insufficiency, diseases of the cardiovascular system, spastic conditions of smooth muscles of other internal organs.

Treatment of infants up to a year

A child under three months is not subject to treatment with Euphyllin. And at this age, the appointment is strictly limited, only in the case of absolute ineffectiveness of other bronchodilators. If there is a threat of pulmonary edema for a child of several months, as well as bronchospasm, acute hypoxia, then the drug is prescribed. Its dose is selected very carefully, the doctor monitors the reaction of the body and the resulting result around the clock.

Newborn children cannot take electrophoresis, pills for obvious reasons. All drugs are administered intravenously, through droppers. The calculation of the amount for the relief of an acute condition is based on six milligrams per 1 kilogram of the baby's body weight. After the disappearance of the threat of hypoxia, the doctor may adjust the dose:

• 3 - 6 months old: multiply the number of weeks by 0.07 and add 1.7 mg;
• age 6-12 months: multiply weeks by 0.05 and add 1.25 mg.

The frequency of injections in the first half of life is up to three times a day. Children aged six months and older, if necessary, are allowed to enter "Eufillin" no more than four times a day.

Small patients are very sensitive to drugs of this kind. A reaction to treatment can be convulsions, respiratory arrest, so the doctor monitors the condition of such patients especially carefully.

Treatment of young children

In the second year of life, the child's body is already stronger, but you should not lose vigilance. The method of selecting the correct, optimal dose remains in force, it is impossible to deviate from it. The route of entry of "Euphyllin" into the body is also preferable to choose injection, drip. This allows you to protect against unwanted, side effects of rapid administration.

The instruction for calculating doses takes into account not only the age of the patient, but also the degree of development of the process: acute or chronic. So, for children from one to three years, the amount of the drug per kilogram of body weight in acute illness should not exceed 5 mg and ingested up to 4 times a day. Children with chronic forms of pulmonary pathologies are recommended to prescribe a dose of not more than 4 mg per kilogram with the same frequency of administration. Children from three to five years old can receive medicine in an amount of 4 to three milligrams, respectively, the severity of the disease with a frequency of administration up to four times a day.

The limitation of the maximum daily amount is up to 7 mg per kilogram of body weight with a single intake and not more than fifteen milligrams per kilogram per day. These doses can be administered through a therapeutic enema, which is less traumatic for children, and even for adult patients, and reduces the possibility of an adverse reaction.

Self-treatment of young children with "Eufillin" is unacceptable!

Inhalation treatment

One of the valuable qualities of the drug is the ability to have the necessary effect in different forms of intake, which makes it possible to use "Eufillin" for children, choosing the dosage and method of administration. The most convenient and effective method of administration for children older than three years is inhalation and iontophoresis, which can be carried out even at home using the Elfor electrophoresis and galvanization apparatus.

The inhalation effect from the inhalation of "Euphyllin" in the vapor state occurs quickly. The drug acts directly in the target organ, which increases the effectiveness of treatment. Modern inhalers allow you to carry out procedures as compactly as possible, with the necessary frequency, efficiency.

For example, the inhalation "Nebulizer" can be transferred, which makes it possible to inhale the therapeutic mixture with "Eufillin" right in the inpatient ward or at home. One of the recipes for preparing a solution with "Eufillin" for inhalation is as follows:

• 100 ml of water must be mixed with the contents of one ampoule of diphenhydramine solution and the same amount of "Euphyllin", the concentration percentage of which is 2%;
• inhalation is carried out no more often than with a break of up to 6 hours;
• the patient's neck is in a fixed state for maximum air permeability.

After inhalation of the therapeutic mixture, the child must be in a calm state for at least 30 minutes. We remind you once again that the independent appointment of "Euphyllin" is unacceptable!

When appoint "Eufillin" in ampoules

Any solutions for parenteral, rectal or inhalation administration are indicated for acute conditions, for the rapid relief of a life-threatening attack or consequences. Also, drugs in ampoules are preferable if there are disorders of the gastrointestinal tract, the patient is in an unclear consciousness, inadequate. Another indication for the appointment of injection forms is the elderly, children's age.

Features of treatment with a tablet preparation

Conscious age of seven years and older allows the use of tablet forms. For eufillin, instructions for the use of tablets for children have been developed. Here, too, the doctor adheres to a strict scheme for prescribing, which contains the following prescriptions:

• The weight of a child up to 30 kg involves the appointment of more than 20 mg per 1 kg per day;
• From three to seven years, the maximum dose is 100 mg per day.

Tablets should be taken with plenty of liquid, plain water is better to prevent complications from the kidneys.

Compress with "Eufillin"

There are recommendations to put a compress on the back of a small child, which includes a solution of "Euphyllin", dimexide, no-spa for stopping a strained cough. There is no reliable information about its effectiveness, but you can get an allergic reaction. It is best to consult a doctor in order to avoid undesirable consequences of such treatment.

Contraindications and side effects

There is a list of absolute contraindications for the appointment of treatment with "Eufillin" not only for children, but also for adults:

• epileptic activity;
• convulsive syndrome;
• kidney failure;
• acute and chronic liver failure;
• mental disorders.

Relative limitations are the following pathologies:

• organic disorders of the cardiovascular system;
• diseases of the gastrointestinal tract with high acidity.

In addition to restrictions on the use and contraindications, there is a list of possible side effects:

• allergic reactions of various manifestations: from rashes on the skin to Quincke's edema;
• disorders of the gastrointestinal tract;
• palpitations, tachycardia;
• vegetative reactions.

Children are prone to adverse reactions from the nervous system. They may be agitated, sleep poorly, act up, react to the drug with convulsions.

Interaction with other drugs and overdose

Antimicrobial agents potentiate the action of Eufillin, this must be taken into account when calculating the dose. Antidiarrheal drugs reduce the absorption of the drug and its effectiveness.

Steroid drugs greatly increase the possibility of adverse reactions with the simultaneous use of a bronchodilator. That is why only the doctor decides on the treatment of "Eufillin", its dose and frequency of administration, especially for children.

A symptom of drug poisoning, convulsions, respiratory arrest, hypercapnia is an emergency condition that requires urgent cancellation of Eufillin, gastric lavage, and antidotes.