Omez is a real aid to digestion. OTC omez

The modern rhythm of life is increasingly leading to digestive problems in adults and children. Dry food, fast food, snacks on the go, flavor enhancers do not contribute to the normal digestion of food. In the structure of morbidity, diseases of the stomach, intestines, and pancreas are firmly entrenched in the first positions. Omez is an effective pharmacological agent used for diseases of the digestive tract in adults and children.

Nutrients entering the human body have a complex chemical structure. The task of the digestive organs is to convert food into simpler substances - sugar, amino acids, fats. The stomach, intestines and pancreas produce special protein substances - enzymes. It is they who turn complex substances into simple ones.

Enzymes are substances that can even digest their own tissues. Therefore, they are contained in the wall of the stomach, pancreatic cells in an inactive form. Enzymes begin to act in the presence of hydrochloric acid. It is produced by special cells of the stomach wall - parietal. The main component of hydrochloric acid is the proton, which parietal cells take from the blood with the help of an enzyme - a proton pump.

Hydrochloric acid is produced in parietal cells

There is a high level of acidity in the stomach. Hydrochloric acid not only activates enzymes, but also kills most bacteria that are ingested with food. However, too high activity of parietal cells leads to excess acidity. It is capable of destroying the wall of the stomach and duodenum, unnecessarily stimulating the pancreas.

The drug Omez blocks the activity of the proton pump contained in the parietal cells. As a result, the production of hydrochloric acid and the level of acidity of gastric juice are significantly reduced. Under these conditions, the activity of pancreatic cells decreases. In addition, Omez fights against the main cause of peptic ulcer - the bacterium Helicobacter pylori.

Omez drug blocks the proton pump in parietal cells

Mechanism of action of Omez - video

Release forms

The drug Omez is produced by pharmaceutical companies in three different forms:


As auxiliary substances, Omez tablets contain:

  • disodium hydrogen orthophosphate;
  • sodium lauryl sulfate;
  • calcium carbonate;
  • mannitol;
  • hydroxypropyl methylcellulose;
  • methacrylic acid copolymer;
  • diethyl phthalate;
  • titanium dioxide.

Auxiliary substances of capsules are:

  • gelatin;
  • glycerol;
  • nipagin;
  • nipazole;
  • sodium lauryl sulfate;
  • titanium dioxide;
  • purified water;
  • dye E 129.

Indications for use

The drug Omez is prescribed for the treatment of many diseases of the digestive tract, the cause of which is the high acidity of gastric juice. First of all, the blockade of the proton pump is required for inflammation of the stomach wall - gastritis, which occurs with excessive release of hydrochloric acid. The process that occurs against the background of low acidity does not require the appointment of Omez.

Peptic ulcer of the stomach and duodenum is successfully eliminated during treatment with Omez. In addition to the influence of the Helicobacter bacterium, excessive acidity of gastric juice plays an important role in the formation of a peptic ulcer. The drug contributes to the speedy tightening and scarring of the ulcer.

Excessive acidity of gastric juice is one of the factors in the development of peptic ulcer

Treatment of gastritis - video

The activity of parietal cells is directly regulated by a specific substance - the hormone gastrin, produced in the pancreas. Often, these cells form a tumor that secretes the hormone in large quantities. The latter leads to excessive acidity of gastric juice, superficial erosive and deep ulcerative defects of the wall of the stomach and duodenum. The disease is called Zollinger-Ellison syndrome. The drug Omez successfully blocks the influence of a huge amount of gastrin, while the acidity level is normalized.

Tumor of the pancreas - the cause of excessive acidity of gastric juice

Heartburn is a negative sign that is directly related to the level of acidity of gastric juice. Most often, this phenomenon occurs when gastric juice enters the esophagus - gastroesophageal reflux. Normally, this process is hindered by a muscle located at the entrance to the stomach - the cardiac sphincter. Her duties include ensuring the movement of food and gastric juice in only one direction - from the esophagus to the stomach. The drug Omez normalizes acidity, eliminating heartburn. In addition, it helps to heal erosions on the wall of the esophagus formed by hydrochloric acid. Therefore, Omez is effective in the treatment of inflammation of the esophagus - esophagitis.

Gastroesophageal reflux leads to the formation of ulcers and erosions of the esophageal wall

Heartburn medication - video

The activity of parietal cells can be increased by drugs belonging to the group of non-steroidal anti-inflammatory drugs - Ibuprofen, Aspirin, Nurofen, Nimesulide. However, the chemicals involved in the process of inflammation play a good role in the body. They make the stomach wall resistant to acid. The drugs also make the internal mucosa vulnerable. Omez eliminates the negative effects of painkillers and anti-inflammatory drugs.

The resistance of the stomach wall to the influence of gastric juice is impaired with a lack of oxygen in the blood and tissues - hypoxia. It can cause severe problems in the body - myocardial infarction, massive trauma and blood loss, burns and frostbite. Under the influence of hypoxia, erosions and ulcers form in the wall of the stomach, which can reach large sizes and cause internal bleeding. Omez protects the cells of the stomach from lack of oxygen, and also promotes the speedy healing of ulcers.

With a lack of oxygen, energy production in the mitochondria suffers.

Inflammation of the pancreas - pancreatitis - is another case where treatment with Omez is effective. The cause of the disease is the premature activation of digestive enzymes, which begin to literally digest not food, but their own tissues. The most powerful trigger factor in this case is acidic gastric juice. The blockade of the proton pump is one of the factors for the normalization of the activity of the gland.

In pancreatitis, enzymes are activated within the pancreatic tissue

Acute pancreatitis - video

Pain in the stomach area is most often the result of gastritis, pancreatitis, gastric ulcer and duodenal ulcer. In this case, the appointment of Omez is an effective means of getting rid of the problem.

Features of the use of the drug Omez

When using the drug Omez, several features must be taken into account. The dosage of the drug will be determined by the attending physician, depending on the age and severity of the disease of the digestive tract. Tablets and capsules of the drug should be taken before meals or during meals with water. They should not be chewed, because this violates the specific shell of the drug.

The child's age of the patient imposes some restrictions on the drug Omez. Children for the treatment of gastroesophageal reflux medicine is prescribed from the age of two and with a body weight of at least 20 kilograms. To eliminate ulcerative and erosive defects of the stomach, Omez is used after reaching four years. In both cases, the drug is used in the form of tablets or capsules. Intravenous administration of the drug to children is not prescribed.

The possibility of using Omez with other drugs

The drug Omez significantly affects the mechanism of action of many drugs used in the form of capsules and tablets. This phenomenon is based on two important factors. Some drugs in the presence of Omez penetrate into the blood through the wall of the stomach better or worse than usual. Other drugs compete with the drug for a place in the liver cells, turning them into an active form. In this regard, the activity of some drugs in the presence of Omez decreases.

Many drugs are converted to their active form in the liver by cytochrome enzymes.

Interaction at the level of the stomach wall is observed with the following drugs:

  • drug Digoxin, used to treat arrhythmias and heart failure. In the presence of omeprazole, the activity of the drug increases, which requires dose adjustment;
  • the drug Clopidogrel, which is used to thin the blood, prevent myocardial infarction and the formation of blood clots inside the vessels (thrombi). Joint use leads to a decrease in the effect of Clopidogrel;
  • antiviral drugs nelfinavir and atazanavir. The combined use of these drugs with Omez is not recommended, since it significantly reduces their effectiveness.

Omez disrupts the chemical transformations in the liver of some drugs:


Contraindications

The drug Omez is prohibited for use in the following cases:


Side effects

The use of the drug Omez may be accompanied by some negative symptoms:


Price range and drugs - analogues

Preparations containing the active substance omeprazole are produced by many pharmaceutical companies.

Preparations containing the active substance omeprazole - table

Name of the drug Release form Price in pharmacies
Omez
  • tablets;
  • capsules.
From 60 to 311 rubles
  • capsules;
  • powder for solution for injection.
  • from 82 to 368 rubles for capsules;
  • from 1639 to 1667 for powder.
  • capsules;
  • powder for preparation of solutions for injections.
  • 209 rubles for powder;
  • from 115 to 560 rubles for capsules.
Losek Maps Powder for solution for injection From 230 rubles
Capsules From 145 rubles
Omitox Capsules From 116 to 131 rubles
Capsules From 21 to 52 rubles

Preparations containing the substance omeprazole - photo gallery

Ortanol is a replacement for Omez
Ultop is used for diseases of the digestive system
Losek is an effective proton pump inhibitor.
Gastrozole contains the active ingredient omeprazole
Omeprazole is the most affordable proton pump inhibitor drug.

To normalize the acidity of gastric juice and treat diseases of the gastrointestinal tract, drugs with a similar type of action are used.

Omez analogues - table

Name of the drug Active substance Mechanism of action Release form Price in pharmacies
Pantoprazole Proton pump blockade Tablets From 128 to 655 rubles
Bismuth tripotassium dicitrate Eradication of the bacterium Helcobacter pylori Tablets From 501 to 954 rubles
Rabeprazole Proton pump blockade Tablets From 712 to 4160 rubles
Blockade of H2-histamine receptors Tablets From 13 to 65 rubles
Lansoprazole Proton pump blockade Capsules From 266 to 414 rubles
Esomeprazole Proton pump blockade Capsules From 207 to 679 rubles

Analogues of the drug Omez - photo gallery

Nolpaza is an effective proton pump blocker
Pariet contains rabeprazole
Ranitidine blocks H2 histamine receptors
Emanera contains esomeprazole
Lancid contains the substance lansoprazole
De-nol promotes the elimination of Helicobacter bacteria

Omez ®(lat. Omez) is an antiulcer drug, a proton pump inhibitor. A high-quality and widespread in Russia Indian generic of omeprazole.

Dosage forms and composition of Omez
The active substance of Omez is omeprazole (lat. omeprazole). On the Russian pharmaceutical market, Omez is present in the form of three variants of enteric capsules containing 10, 20 or 40 mg of omeprazole, a powder for oral suspension and a lyophilisate for solution for infusion. Capsules are hard gelatinous, filled with white or almost white granules of omeprazole. The capsules look like:
  • 10 mg - opaque with a yellow body and a light purple cap, the inscription "OMEZ 10" on both parts of the capsule
  • 20 mg - transparent with a colorless body and a pink cap, the inscription "OMEZ" on both parts of the capsule
  • 40 mg - opaque with a light purple body and a yellow cap, the inscription "OMEZ 40" on both parts of the capsule
Excipients capsules Omez 20 mg, including shell: mannitol, lactose (10.14 mg), sodium lauryl sulfate, sodium hydrogen phosphate, sucrose, hypromellose, methacrylic acid copolymer, sodium hydroxide, macrogol 6000, purified talc, titanium dioxide, gelatin, propyl parahydroxybenzoate, methyl parahydroxybenzoate, water, azorubine dye.

Excipients capsules Omez 10 and 40 mg, including the shell: mannitol, crospovidone, poloxamer 407, hypromellose, meglumine, povidone K30, methacrylic acid and ethyl acrylate copolymer, triethyl citrate, magnesium stearate, sodium lauryl sulfate, water, gelatin, titanium dioxide, dyes (iron oxides yellow and black, brilliant blue, Sunset Sunset) yellow, Charming Red, phloxin B, indigo carmine, quinoline yellow), n-butanol, propylene glycol, S-1-8114 ink, ethanol, methanol.

Indications for use Omez
  • exacerbation of gastric and duodenal ulcers
  • erosive and ulcerative esophagitis
  • peptic ulcers that developed while taking non-steroidal anti-inflammatory drugs
  • stress ulcers
  • Zollinger-Ellison syndrome, systemic mastocytosis
  • erosive and ulcerative changes in the upper gastrointestinal tract, developed in patients with cirrhosis of the liver
  • eradication (destruction) Helicobacter pylori in the gastric mucosa of infected individuals (only as part of a combination of drugs)
  • anti-relapse treatment of patients with peptic ulcers prone to frequent exacerbations and complications
  • anti-relapse treatment of gastroesophageal reflux disease.
Method of application of Omez and doses
Omez capsules are recommended to be taken in the morning (regardless of food intake), the capsule should be swallowed whole with a liquid. In the absence of special prescriptions from a doctor, the following approximate doses are recommended:
  • duodenal ulcer - 20 mg Omez per day for 2-4 weeks (in resistant cases up to 40 mg per day)
  • stomach ulcer - 20 mg per day for 4-6 weeks (in resistant cases up to 40 mg capsules per day)
  • erosive and ulcerative esophagitis - 20-40 mg per day for 4 weeks, in severe cases of the disease, the course is extended to 6-8 weeks
  • anti-relapse treatment of duodenal and gastric ulcers - 20 mg of Omez per day
  • anti-relapse treatment of gastroesophageal reflux disease - 20 mg per day for a long period (up to six months)
  • Zollinger-Ellison syndrome - the dose of Omez is selected individually depending on the initial level of gastric secretion, usually starting from 60–80 mg per day, a dose of 80 mg or more is divided into 2 doses; treatment is effective if it is possible to achieve a decrease in the level of gastric secretion to 10 mmol/hour and below
  • eradication Helicobacter pylori as part of special schemes containing, in addition to Omez, two antibiotics (only Omez for eradication Helicobacter pylori not applicable) - for specific schemes, see the article " Helicobacter pylori ».
OTC Omez
Omez 10 mg is available from pharmacies without a prescription and can be used independently by patients for the symptomatic treatment of persistent heartburn. The maximum daily dose should not exceed 20 mg. The lowest effective dose should always be used. The maximum period of treatment without contacting a doctor is 14 days. The interval between 14-day courses of treatment should be at least 4 months. If within 2 weeks there is no relief of symptoms, a visit to a specialist is necessary.
Omez properties
Omez belongs to the group of drugs that suppress gastric secretion. It inhibits the proton pump H + -K + -ATPase in the parietal cells of the stomach and thereby blocks the final stage of hydrochloric acid secretion. This leads to a decrease in the level of basal and stimulated secretion, regardless of the nature of the stimulus. After oral administration of Omez, the antisecretory effect occurs within the first hour and persists for a day, the maximum effect is achieved after 2 hours. When you stop taking Omez, secretory activity is completely restored after 3-5 days.
Professional medical publications related to the treatment of gastrointestinal diseases with Omez
  • Uspensky Yu.P., Sablin O.A. Clinical and pharmacoeconomic aspects of the use of the drug "Omez" in the treatment of peptic ulcer. Gastro Bulletin. - 2001. - No. 1.

  • Minushkin O.N., Maslovsky L.V., Shuleshova A.G., Sorokina L.I. Evaluation of the efficacy and safety of monotherapy with omez at a dose of 20 mg twice a day in the treatment of GERD // Clinical perspectives of gastroenterology, hepatology. - 2003. - No. 2. - p. 11–13.

  • Gorbakov V.V., Makarov Yu.S., Golochalova T.V. Comparative characteristics of antisecretory drugs of various groups according to daily pH monitoring. Lechachy vrach. 2001. - No. 5–6.

  • Minushkin O.N. Complex issues of therapy with proton pump inhibitors // Attending physician. - 2007. - No. 6.

  • Pasechnikov V.D., Pasechnikov D.V. How to achieve maximum effectiveness of drug therapy for gastroesophageal reflux disease // Farmateka. - 2008. - No. 13. - With. 68–72.

  • Pasechnikov V.D., Goguev R.K., Pasechnikov D.V. Comparison of the acid-suppressive effect of omeprazole generics // Clinical perspectives of gastroenterology and hepatology. - 2010. - No. 5.
On the site in the literature catalog there is a section "Omeprazole", containing links to medical articles relating to the treatment of diseases of the digestive tract with omeprazole and Omez.
Pharmacokinetics of Omez
Omeprazole, the active substance of Omez, is enclosed in acid-resistant granules that dissolve in the intestines. Omeprazole is rapidly absorbed, peak plasma concentration is reached after 0.5-1 hour. The bioavailability of omez (omeprazole) is 30-40%. Clearance 500–600 ml/min. Plasma protein binding reaches 90%. Omez (omeprazole) is almost completely metabolized in the liver and excreted mainly in the urine. In patients with chronic liver diseases, the bioavailability of the drug increases to 100%, and the half-life increases to 3 hours, the clearance decreases to 70 ml / min. In patients with chronic kidney disease (creatinine clearance 10-62 ml / min), the distribution of omeprazole is the same as in healthy volunteers. Since renal excretion is the main route of elimination of omeprazole metabolites, elimination slows down in proportion to the decrease in creatinine clearance. In elderly patients, the elimination of omeprazole is reduced and the bioavailability is increased.
Contraindications to the use of Omez
  • hypersensitivity to omeprazole
  • childhood
  • pregnancy
  • lactation
Precautions when using Omez
In the presence of any alarming symptoms (for example, such as significant spontaneous weight loss, frequent vomiting, dysphagia, vomiting of blood or melena), as well as in the presence of a stomach ulcer (or a suspected stomach ulcer), the possibility of malignancy should be excluded, therefore, in these cases before and after the end of treatment, endoscopic control is mandatory to exclude a malignant neoplasm, since Omez therapy can hide symptoms and delay correct diagnosis. In patients with severe hepatic insufficiency, the dose of Omez should not exceed 20 mg.

Long-term use of Omez increases the risk of hip, wrist, and spine fractures when taken long-term or at high doses (“FDA Warning”).

Side effects of Omez
Omez is well tolerated by patients. In the treatment of Omez in rare cases, the following, usually reversible, side effects may occur:
  • digestive system: diarrhea or constipation, abdominal pain, dry mouth, taste disturbances, stomatitis, transient increase in plasma liver enzymes.
  • nervous system: headache, dizziness, agitation, drowsiness, insomnia, paresthesia, in predisposed patients - depression and hallucinations.
  • musculoskeletal system: muscle weakness, myalgia, arthralgia.
  • skin reactions: rash, urticaria, erythema multiforme.
  • other: visual disturbances, peripheral edema, increased sweating, fever.
Interaction of Omez with other drugs
The metabolism of Omez (omeprazole) occurs in the liver through the cytochrome P450 system, so care should be taken when combined with diazepam, phenytoin, since omeprazole can slow down their elimination, which requires a dose reduction of these drugs. With simultaneous drug treatment of several diseases, it is sometimes advisable to replace Omez with pantoprazole (Bordin D.S.).
Comparison of Omez with other proton pump inhibitors
Omez is a budget quality Indian generic of omeprazole. A comparison of Omez (omeprazole) with other proton pump inhibitors is described in the article " Omeprazole» in the section «Comparison of omeprazole with other proton pump blockers». The same article describes the sometimes manifesting effect of "omeprazole resistance".
General information
Omez, 10 mg capsules, are dispensed in pharmacies without a prescription, 20 and 40 mg capsules - by prescription.

Instructions for the medical use of the drug Omez (enteric capsules, 10 mg), approved by the Ministry of Health of Russia on May 30, 2016 (pdf, download).

According to the pharmacological index, Omez belongs to the Proton Pump Inhibitors group. According to ATC - to the group "Proton pump inhibitors", code A02BC01.

Manufacturer Omeza: "Dr. Reddy's Laboratories Ltd" (Dr. Reddy's Laboratories Ltd) India; Sofarimex Industria Quimica and Farmaceutica (Portugal).

Omez Insta and Omez D

In Russia, as well as some other countries, drugs are registered that contain the word "Omez" in the name, but slightly differ in pharmacological action from Omez:

Omez ® D- a combined drug with the active substance omeprazole + domperidone.

Omez is intended for the prevention and treatment of gastritis or stomach ulcers. This tool helps to eliminate the symptoms of the disease, while it has minimal side effects.

Most doctors and patients who have undergone treatment recommend it. How to take Omez for gastritis?

This drug belongs to a new group of drugs that can lower the level of acidity.

What is gastritis

Gastritis is an inflammatory process in the stomach that affects the mucous membrane. For a long time, this disease was not treated and did not attach importance to it.

It was believed that this is a person's retribution for the fast pace of life. But statistics say that most of the neglected cases of a disease such as gastritis gradually turns into an oncological formation.

The main cause of this disease is high acidity.

But the change in the level of acid occurs due to autoimmune diseases, untimely nutrition, side effects from drugs, poor quality products.

Also recently, another reason has been identified - the presence of the bacterium Helicobacter pylori.

Why be treated with Omez

There are many options for the effect of the drug on the function of the gastrointestinal tract. It is necessary to take Omez for the following violations:

  1. Gastric ulcer.
  2. Inflammatory process localized in the lower part of the esophagus.
  3. With gastritis with an increased level of acidity or with atrophic gastritis.
  4. Inflammation of the pancreas.
  5. With gastroduodenitis.

Omez with gastritis helps to normalize the level of acidity. Regardless of what factors caused the disease, a positive effect has been proven.

How to take Omez: instructions for use

Only a qualified specialist can determine the required dosage for the patient. If you follow the recommendations, then there is a chance to get the desired result. Omez is made in the form of capsules for oral administration.

There are a very large number of types of gastritis: atrophic, erosive, with high or low acidity.

The instruction has clear instructions that it is necessary to take the drug depending on the type of disease.

Regardless of the type of disease, the course of gastritis therapy is a rather lengthy process. The dosage depends on the stage of the disease.

Symptoms of inflammation in the stomach are accompanied by diarrhea, heaviness in the abdomen, nausea, heartburn. They can be eliminated quickly enough with the help of a drug such as omez.

If Helicobacter pylori is present, antibiotics are prescribed. The type of antibiotic and its dosage depends on the severity of the process.

With gastroduodenitis, you need to drink two tablets a day. Tablets should be taken for 30-60 days.

If gastritis occurs along with a stomach ulcer, it is necessary to use Omez once a day before bedtime. At this time, it is considered the most effective.

If there are painful sensations in the stomach, then you need to use 2 capsules a day: one in the morning and one in the evening.

Treatment takes place throughout the week. After that, you need to take one tablet a day for 10 days in a row for the purpose of prevention.

With gastritis of a chronic nature, it is necessary to undergo a course of treatment for up to 4 months. The patient should take 1 tablet per day.

Also, in the presence of a chronic disease, it is recommended to use drugs every autumn and spring to prevent the occurrence of seasonal exacerbations.

You need to use medicines a month before the onset of seasonal gastritis.

The tablet should be taken whole, without chewing. The maximum result can occur only a few hours after taking the drugs.

What can happen with prolonged use of Omez? These are drugs of a new era and new time, which have a minimum number of contraindications. One of the main ones is individual intolerance to the drug.

Also, with atrophic gastritis, it is strictly forbidden to take Omez. Since Omeza is able to lower the level of acidity, and atrophic gastritis leads to a decrease in the pH level of gastric juice.

During pregnancy and lactation, the appointment of this drug is contraindicated. If necessary, only a doctor can prescribe Omez to a pregnant woman after assessing the degree of risk.

Side effect

Despite the minimal side effect, the following symptoms may occur:

  1. Dizziness, frequent intense headaches.
  2. Constipation or diarrhea. Irritable Bowel Syndrome.
  3. Vomiting and nausea.
  4. Allergic reaction in the form of rashes on the skin.

If you have symptoms, you need to take a break and make sure that the medication is the cause.

In most cases, such signs may indicate the manifestation of diseases of the gastrointestinal tract.

An overdose of a drug such as Omez can lead to the following conditions: migraine, pain in the stomach, dry mouth, lower body temperature, decreased visual acuity, dizziness.

Side effects from the use of the drug disappear on their own, as soon as the patient stops using Omez.

Forbidden to take

The number of contraindications for the use of a drug such as Omez are limited, but still exist. The drug should not be taken during pregnancy, regardless of the term.

It is forbidden to take Omez in the presence of pituitary adenoma, impaired functioning of the stomach and intestines, as well as bleeding in the internal organs of the gastrointestinal tract.

It is necessary to take the drug under the close supervision of a doctor.

You should also tell the gastroenterologist if you have been taking vitamins, dietary supplements, medications for the treatment of human immunodeficiency syndrome.

How to buy Omez

You can buy it in every pharmacy in the country without a doctor's prescription. The pricing policy directly depends on the number of tablets in the package or capsules.

Drug analogues

If an individual reaction occurs, then it is necessary to change the medicine to a more effective and without side effects.

For example, it can be Omegast, Omegast, Pantap, Ontime, Novobismol, Famotidine.

In order to avoid adverse reactions, you should consult with your doctor about which drug will be the best and at what dosage it should be taken.

Despite the fact that Omez is considered the safest, it should be taken only under the close supervision of a doctor. He will diagnose and determine the condition of the internal organs.

This must be done, because such a serious disease as stomach cancer can be hidden behind the symptoms of gastritis.

Omez is a drug widely represented in Russian pharmacies. Therapy of diseases of the stomach and intestines includes a variety of drugs, and the use of Omez in treatment tactics, despite the indications for admission in case of peptic ulcer, is not limited to this pathology. Instructions for use of the drug describe in detail in which cases it is possible to include Omez in the complex therapy of diseases of the gastrointestinal tract, how to take the drug, what therapeutic and side effects are likely if the prescribed doses are observed and not observed.

What kind of drug is Omez?

Omez belongs to the drugs of directed action from the group of antiulcer drugs related to proton pump inhibitors. The active substance and its main analogue is omeprazole (Omeprazole), a chemical compound that blocks the process of hydrochloric acid synthesis at the last stage.

Hydrochloric acid is an essential element of the digestion process, ensuring the separation of food into its constituent elements and facilitating its absorption in the small intestine. An excess of this acid irritates the walls of the stomach, which is especially negative in the presence of erosions and ulcerations of the mucosa. Suppression of the secretion of hydrochloric acid by taking Omez reduces irritation of the walls of the stomach, regardless of the etiology and type of irritant.

Domperidone is the second component of Omez D, a combination drug based on omeprazole. This tool has an additional effect on the smooth muscles of the digestive tract. Due to the presence of domperidone, Omez D has an antiemetic effect, reduces the likelihood of reflux, manifestations of heartburn, leading to a state of increased tone of the muscle tissue of the lower esophageal sphincter, and also causes intestinal contractions, which enhances its peristalsis and accelerates the emptying process.

Omez and Omed D are drugs of almost immediate action. The therapeutic effect occurs within 45-60 minutes after oral administration and lasts for 24 hours. The maximum concentration of active substances is observed 2 hours after administration. The decrease in the concentration of hydrochloric acid with daily intake reaches an indicator of 70-80%, depending on the individual reactions of the patient's body. To achieve a single therapeutic effect, a course of at least 4 days is recommended.

The active ingredients of the drugs are absorbed in the gastrointestinal tract, the process of metabolism occurs in the liver tissues, the excretion in the form of a metabolite is carried out by the kidneys with urine (80%) and the intestines with feces (20%). The blocking of the secretory function of the stomach disappears after the course of treatment is canceled on its own within 3 days, the level of synthesis and secretion is restored.

Omez: various forms and composition of the drug

Omez is a drug presented in several versions both in the form of the drug release and in its composition. Monocomponent Omez is available in two forms:

  • enteric-coated capsules. The composition includes 20 mg of the active substance (omeprazole) and related components. The capsules are made on the basis of gelatin, consist of a transparent and pink transparent parts, each of which has the inscription OMEZ. Inside the enteric capsule are rounded white granules. The capsules are packaged in plastic strips covered with foil. Omez carton contains 3 strips of 10 capsules each;
  • Omez Insta is a form of release of the drug Omez, intended for patients who have difficulty swallowing capsules. As part of the drug omeprazole (20 mg per dose), related substances: sucrose, xylitol, mint flavor, sodium bicarbonate, gum. The drug is available in the form of a powder for self-preparation of a suspension (a mixture of the drug in a liquid). Each dose of the drug is placed in a separate paper bag with moisture protection, depending on the number of bags in the package, Omez Insta No. 5, No. 10, 20, 30 is isolated.

Omez D is a drug of combined action based on the presence of omeprazole and domperidone (10 mg each, respectively). Produced in the form of enteric gelatin capsules, consisting of two parts: purple and transparent, with the name of the drug and a logo to protect against counterfeiting. In the capsule, the active ingredients are presented in the form of a white powder. This form is presented No. 10, in each carton - 10 capsules of the drug.

In hospitals and clinics, the drug can be presented in the form of a dry mixture, intended for infusion transfusions, mainly for the prevention of postoperative complications.

Indications for taking the drug Omez

Omez is a medicine with a fairly wide range of indications, despite belonging to the group of antiulcer drugs. Its appointment is justified in the following cases:

  • in courses of treatment and preventive measures of exacerbations, chronic course, relapses of peptic ulcer of the stomach and duodenum;
  • in the presence of symptoms of reflux esophagitis;
  • when hypersecretion of the stomach is detected (stress lesions of the stomach walls caused by increased synthesis of hydrochloric acid, Zollingen-Ellison syndrome, systemic manifestations of mascidosis, adenomatosis of polyendocrine etiology, etc.);
  • ulcerative, erosive lesions of the walls of the gastrointestinal tract with long-term use of non-steroidal anti-inflammatory drugs (aspirin, ibuprofen, etc.);
  • as part of complex therapy as a proton pump inhibitor in pathologies and diseases of the gastrointestinal tract caused by H. pylori microorganisms.

Omez D is used for manifestations of dyspepsia, gastroesophageal reflux resistant to other drugs, gastritis accompanied by increased acidity of the gastric environment, hypersecretion of the stomach, etc.

Contraindications to taking Omez and Omez D

The appointment of taking Omez and Omez D drugs, in accordance with the instructions for use, is limited in the following cases:

  • early childhood. The use of Omez in children is strictly limited to specific indications and age limits;
  • the presence of individual intolerance to the components of the drug (fructose, sucrose, benzimidazole groups, etc.), hypersensitivity reactions;
  • with mechanical obstruction of the intestine, perforation of the walls, the presence of bleeding in the organs of the gastrointestinal tract, previous therapy for surgical intervention in the gastrointestinal tract;
  • when combined with certain medications, including Warfarin, Diazepam, Ketoconazole, Clarithromycin, St. John's wort derivatives (decoctions, tinctures, capsules and tablets based on medicinal plants), etc.

In case of renal, hepatic insufficiency, a history of jaundice, episodes of ulcer perforation, as well as during pregnancy and lactation, omeprazole preparations are taken only according to the doctor's indications.

Rules for taking Omez

The duration of the course of therapy and the required dosage are set by the attending physician based on the diagnosis, the clinical picture of the disease (duration of the disease, stage, severity of symptoms), the presence of concomitant pathologies and the individual characteristics of the patient.

According to the instructions, the drug in any of the above forms is taken orally. The recommended time of admission is half an hour before a meal or during a meal. The capsules are swallowed whole, without chewing, washed down with a sufficient amount of liquid. If necessary, you can take granules without a capsule shell, mixing them with water with a small amount of acid (lemon, citrus juice). It is forbidden to mix granules with milk or dairy products, carbonated drinks. The resulting mixture is consumed immediately, it is not subject to storage.

If it is impossible to take whole capsules, experts recommend not resorting to the method of dissolving granules, but using the Omez Inta suspension form. To mix the suspension, the contents of the package are poured into a clean container and up to 2 tablespoons of boiled water at room temperature are added.
Depending on the disease and the course of treatment, it is possible to take from 1 to 6 capsules or Omez powders per day, the duration of therapy depends on the goals. In preparation for surgery, a single dose is possible; in the treatment of diseases of the gastrointestinal tract, the average duration of treatment is 2-8 weeks.

Omez: Possible Side Effects

The drug is well tolerated by patients with a low likelihood of side effects. In studies of monocomponent Omez, the following possible side effects have been identified:

  • shift in the blood formula due to disorders of the hematopoietic system (thrombocytopenia, agranulocytosis, pancytopenia, leukopenia);
  • in the presence of diseases and pathologies of the central nervous system while taking Omez, headaches, irritability, dizziness, depressive states may occur;
  • on the part of the organs of the gastrointestinal tract, such side effects of the drug as a feeling of nausea, dyspepsia, vomiting, dry mouth, induration, discoloration of feces (melena), etc .;
  • allergic skin reactions, hypersensitivity to UV rays, hair loss may occur.

If you experience these symptoms, you should consult with your doctor.

The cost of the drug

The price of Omez depends on the form of release and the composition of the drug. On average, 30 capsules cost from 220 to 270 rubles, Insta suspension powder - from 80 rubles / 5 packages.

Omez: analogues and substitutes

Analogues of this drug include all monocomponent drugs based on omeprazole, as well as pantoprazole (Nolpaz drug). Among them may be drugs with different dosages, countries and manufacturers. Direct analogues present on the Russian pharmaceutical market include: Omeprazole, Gastrozole, Omezol and others.
What is the difference between this drug and analogues? Omeprazole, a drug with the same active ingredient, unlike Omez, was produced not in India, but in Russia. The amount and chemical formula of the active substance are the same, however, there are no additives in Omeprazole, which, on the one hand, reduces the likelihood of allergic reactions and individual intolerance to additional substances, on the other hand, increases the likelihood of side effects. The release form is the same - capsules with an enteric-coated shell. The cost of the Russian analogue is lower than foreign-made medicines.

Today we will talk about such a drug as Omez, the instructions for use of which will be considered in detail.

We will also tell you about Omez analogues in tablets, ampoules and capsules.

General information about the medication

Before we talk about the method of using Omez, and what this medicine helps with, you need to describe its medicinal properties.

The drug belongs to the group of inhibitors, in medicine it is used as an antiulcer agent.

The main active ingredient is omeprozole. It affects the process of synthesizing hydrochloric acid, blocking it.

As a result, peptic ulcer quickly disappears. However, in order not to harm your health, it is important to know how to take this drug correctly.

The composition of Omez drugs also includes another active ingredient - domperidone. It allows you to increase the tone of the lower sphincter of the gastrointestinal tract. Also, this substance helps to improve intestinal motility and accelerated emptying.

Omez medicine acts quickly. The therapeutic effect after taking it occurs within 1 hour.

You can take this medication for medicinal purposes not only for adults, but also for children.

It is rapidly absorbed into the mucosa of the gastrointestinal tract and metabolized in the liver. The drug is excreted from the body due to the functioning of the kidneys.

For the gastrointestinal tract, the medicine Omez is harmless. The functioning of this organ is fully restored after 2-3 days.

Release form

In pharmacies, you can find several variations of this medicine. Its release form:

  • Capsules (gelatin capsules are also available).
  • Tablets.
  • Ampoules.
  • Powder (Omez Insta).

Omez capsules are purchased most often. Their color is different: black, pink or yellow. Sometimes they have no color at all.

Inside each capsule there are white granules containing the active ingredients.

1 capsule of the drug contains 20 mg of omeprozole. In one drug package - 30 capsules.

The drug, dispensed in a gelatin shell, has a white powder inside. It is sold in cardboard boxes of 10 capsules inside.

The drug in the form of a powder is intended for the preparation of a suspension. Omez Insta has a very pleasant color and aroma.

The powder has several additional components, namely:

  • sodium bicarbonate.
  • Sucrose.
  • Xylitol.
  • Gum.
  • Mint flavor.

What can replace Omez

Fortunately, the pharmaceutical market daily delights consumers with new, more profitable offers.

We invite you to talk about cheap analogues of Omez (how to replace it). Consider the most popular of them:

  • Gastrosol. After taking it, the therapeutic effect begins after 3-4 hours. Gastrozole contains gastric secretion, its activity is 1 day. To prolong the medical effect, repeated medication is required.
  • Ortanol. This is the most popular analogue of Omez. When to take Ortanol? It is prescribed for violation of the secretory function of the gastrointestinal tract. Ortanol has the same medicinal properties as Omez.
  • Ranitidine. The therapeutic effect after taking this medication comes due to its hydrochloride content. Ranitidine is available in tablet form. Its feature is the short duration of the therapeutic effect. It is allowed to use the medication only after consulting a doctor.
  • Omeprazole. This is the cheapest substitute for Omez. Its intake does not depend on the use of food, which makes it a universal drug for relieving the symptoms of gastric diseases.

Indications for use

Let's talk about Omez tablets: what do they help from? Doctors advise taking it to patients suffering from:

  • Esophagitis. The drug allows you to eliminate the symptoms of reflux.
  • Ulcerative lesions of the duodenum or stomach. You can also drink Omez to prevent the occurrence of these ailments.
  • Zollinger-Ellison syndrome or stress ulcers.
  • Systemic mastocytosis.
  • pancreatitis. The drug is advised to drink and for the prevention of this disease.
  • Adenomatosis, etc.

Prescribe medications containing omeprozole for gastritis with high acidity.

When not to take Omez

Medicines for the treatment of gastric pathologies often have many restrictions on admission. The main contraindications to the use of Omez:

  • Pregnancy, breastfeeding period.
  • Bleeding in the bowel or gastrointestinal tract.
  • Perforation of the gastric or intestinal walls.
  • Intestinal obstruction due to mechanical damage.
  • Individual intolerance to some components of the drug.

For children over 12 years of age, this remedy is prescribed only as a last resort. With caution, it should be taken by patients suffering from hepatic or renal insufficiency.

As for the powder form of Omez, sometimes doctors write a prescription for it to pregnant patients.

Expectant mothers should drink the suspension only under the supervision of their doctor.

Side effects

Like any drug, taking Omez can cause side effects in the body.

To prevent this from happening, you need to carefully read the instructions attached to it. But first things first.

The main side effects of the drug:

  • Intestinal obstruction. Most often it occurs due to an overdose of the drug.
  • Diarrhea, frequent bowel movements.
  • Flatulence (bloating).
  • Nausea, sometimes accompanied by vomiting.
  • Increased gas formation in the intestines.
  • Stomatitis.
  • Violation of the functioning of the liver.
  • Change in taste preferences.
  • Dryness in the mouth, problems with salivation.
  • An imbalance in the blood vessels. In rare cases, leukemia may occur.
  • Malaise, increased fatigue.
  • Visual impairment.
  • Deterioration of coordination of movements.
  • Hepatic encephalopathy.
  • Formation in the stomach of a cyst.
  • Increased swelling.
  • Allergy, manifested in the form of skin rashes, severe itching, difficulty breathing, etc.

Despite the large number of adverse reactions, one should not think that they appear in 100% of cases. They are caused by 2 factors. Firstly, this is the wrong method, and, secondly, non-compliance with medical recommendations.

If an allergic reaction occurs, you should stop drinking this medication for medicinal purposes. Now let's talk about the instructions for using Omez.

Admission rules

Instructions for use:

  1. In violation of intestinal motility and the presence of stomach ulcers, the drug should be drunk twice a day, 20 mg. It is advisable to do this in the morning and evening. The recommended course of treatment is 3 weeks. In the absence of positive dynamics, the gastroenterologist can increase therapy up to 2 weeks.
  2. To stop the symptoms of Zollinger-Ellison, you need to drink the medicine 1 time per day, 60 mg.
  3. To prevent the re-development of gastric diseases, Omez is recommended to drink 20 mg 1 time per day.
  4. With pancreatitis, this medicine should be drunk 3 times a day for 40 mg. The course of treatment is determined by the doctor. It can last from 2 to 4 weeks. It depends on the severity of the disease.
  5. In case of liver failure, Omez is drunk 1 time per day, 20 mg.
  6. With cholelicobacter, the drug is drunk twice a day, 40 mg each.
  7. For the treatment of gastritis with high acidity, gastroenterologists recommend drinking Omez 1 capsule once a day.

Intravenous administration of the drug is also possible. In this case, a single dose is 40 mg.

At an advanced stage of the disease, doctors increase the daily dosage to 70 mg.

If the patient took Omez incorrectly and his body reacted accordingly, you should not postpone the trip to the medical facility.

In some cases, the patient will require urgent hospitalization to provide medical care.

Important to take note

Before prescribing Omez to a patient for the treatment of ulcers, a gastroenterologist must exclude the development of an oncological process.

Why is it important? Taking medications containing omeprozole can mask the alarming symptoms of a malignant process.

Therefore, the correct diagnosis will be delayed. Patients suffering from severe renal insufficiency should drink Omez with caution, otherwise they may experience complications. Their daily dosage should not exceed 20 mg.

However, sometimes, if you have problems with swallowing, doctors advise you to mix the medicine powder with applesauce.

After preparing the mixture, it must be swallowed immediately. Keeping the powder mixed with applesauce is highly discouraged.

Sometimes doctors advise drinking Omez in parallel with meals. In order to prevent the occurrence of complications, it is important to follow all medical prescriptions.

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