The area of ​​the material room in the pharmacy. Familiarization with the finished medicines department, device, equipment and equipment of workplaces, product nomenclature, assortment groups of the finished medicines department. Pharmacy departments and their functions

Thousands of assortment items in the computer, tens of thousands of packages on pharmacy shelves, and all of them bring health to our customers! True, only if we store them correctly. The abundance of goods in the pharmacy and the many storage modes will confuse the layman, but we, professionals in the pharmaceutical market, do not have to comply with the requirements of the pharmacopoeia.

Temperature and humidity in the pharmacy

Storage of medicinal products for medical use is carried out in accordance with the requirements of the state pharmacopoeia and regulatory documentation, as well as taking into account the properties of the substances that make up them. In addition to the pharmacopoeia, the microclimate of the pharmacy is regulated by three main documents: Order of the Ministry of Health of the Russian Federation No. 377 dated 11/13/1996 "On approval of requirements for the organization of storage in pharmacies of various groups of medicines and medical products", Order of the Ministry of Health and Social Development of the Russian Federation dated August 23, 2010 No. 706n "On Approval of the Rules for the Storage of Medicines" and Order of the Ministry of Health of the Russian Federation dated October 21, 1997 No. 309 "On Approval of Instructions on the Sanitary Regime of Pharmacy Organizations".

The State Pharmacopoeia of the Russian Federation (12th edition, entered into force in 2009) contains detailed information on the temperature regimes for storing medicines and substances for their manufacture:

  • in the refrigerator: 2-8⁰C
  • cold or cool place: 8-15⁰C
  • room temperature: 15-25⁰C
  • warm storage mode: 40-50⁰C
  • hot storage: 80-90⁰C
  • water bath temperature: 98-100⁰C
  • ice bath temperature: 0⁰С
  • deep cooling: below - 15⁰C

In a pharmacy that offers visitors only ready-made dosage forms, usually the first three temperature modes are used and constant monitoring of air humidity. An electronic hygrometer or psychrometer is used to measure relative humidity. There may be only one hygrometer in a small pharmacy, but a thermometer should be available not only near pharmacy shelves, but also in refrigerators. All instruments must be properly certified and calibrated. The thermometer is placed on the inner walls of the room away from heating devices at a height of 1.5-1.7 m from the floor and at a distance of at least 3 m from the doors. The recommended air temperature in the pharmacy is 16-20⁰С, relative air humidity is up to 60% (in some areas up to 70%). It is in this interval that the correct storage of most dosage forms with the “room temperature” storage mode is ensured (for example, most manufacturers recommend storing aerosols at a temperature of 3-20⁰С).

Checking the temperature and humidity in the pharmacy lies on the shoulders of the pharmacist: at least once a day, the readings of the devices are entered into a temperature and relative humidity record (journal), which must be entered in each department of the pharmacy. Separate accounting cards should be not only in the trading departments, but also in the storage rooms - the material room, the goods acceptance area. The air temperature and humidity register can be kept in electronic form with data archiving for the last year. Handwritten journals and accounting cards are stored for one year, not counting the current one (Order No. 706n).

If the temperature in the pharmacy does not meet the required, it is worth taking care of air conditioning or additional heating. Heating and ventilation systems should be located so as to exclude sudden temperature changes and excessive heating of the medicines storage area. When you turn on the air conditioner, do not forget to control the humidity: even the most modern climate systems tend to “dehydrate” the environment.

It is advisable to have at least two refrigerators or a two-chamber refrigerated display case in the pharmacy with the possibility of separate temperature settings. ATP storage temperature - 3-5⁰С, many suppositories are stored at a temperature of 8-15⁰С - it is impossible to store them in one refrigerator.

Where to define a product?

A common mistake when receiving goods in a pharmacy is placing boxes brought by a warehouse forwarder on the floor. This is unacceptable: both in the storage area and in the receiving area there must be pallets and undercarriages on which boxes with goods can be placed.

Information about the storage mode of the drug is always present in the annotation to it and on the secondary (consumer) packaging, if any, therefore, in the process of accepting goods from the distributor's warehouse, you can not rely on memory, but follow the manufacturer's instructions (Order No. 377). The temperature requirements are also described in the accompanying delivery documents: many pharmaceutical warehouses mark preparations to be stored in the refrigerator with a special icon; there is the necessary information in the documents confirming the quality of the goods (certificate, hygiene certificate, etc.).

Often in the annotation there is a recommendation to store the drug in a dry place. The Pharmacopoeia considers a dry place with a relative humidity of not more than 40% at room temperature.. During inspections of pharmacies by Roszdravnadzor, a violation of this storage regime is often encountered - not all pharmacy organizations can allocate a separate room and provide such low humidity there for placing herbs and a number of other drugs that should be stored in a dry place. The pharmacy is recommended to allocate a separate room for such drugs and dry the air in it to the required humidity.

An excellent knowledge of regulatory documents comes to the aid of a pharmacist. Order No. 706n, issued many years after Order No. 377, states: “In bulk medicinal plant materials should be stored in a dry (no more than 50% humidity), well-ventilated area in a tightly closed container. The packaged medicinal herbal raw materials are stored on racks or in cabinets. Despite the fact that this provision is somewhat contrary to the pharmacopoeia, it should be guided by it: medicinal raw materials in the manufacturer's packages are packaged and can be stored in display cabinets on the sales floor. Yes, sometimes a pharmacy manager has to be a bit of a lawyer to defend his point of view during the check!

Some pharmaceutical products require additional protection from light (herbal medicinal raw materials, antibiotics, tinctures and extracts, vitamin complexes, essential oils, nitrates, and many others). They come to the pharmacy in packaging made of light-protective materials, but they should be stored in a dark room or in tightly closed cabinets or on shelves, provided that measures are taken to prevent direct sunlight or other bright directional light from falling on these drugs (use of reflective film, blinds , visors, etc.).

Narcotic, psychotropic, potent and poisonous drugs have their own special storage rules, but their observance is more about ensuring safety than maintaining the quality of the drug in a pharmacy. The rules for the storage of narcotic drugs and psychotropic substances are established by Decree of the Government of the Russian Federation of December 31, 2009 N 1148.

Requires special attention placement of flammable medicines in a pharmacy- alcohol, alcohol solutions, tinctures, extracts, organic oils and a number of other products. For their storage, a separate cabinet should be allocated away from heating devices (at least 1 meter), in which bottles can only be placed in one row in height.

In a pharmacy, the rules for storing drugs are usually observed, but what happens after the sale of the drug? Many of our customers place a first aid kit in the bathroom or kitchen, which negatively affects the quality of medicines and can significantly reduce their effectiveness, because it gets hotter in the kitchen during cooking, and lovers of hot water procedures in the bathroom can “steam” the temperature up to 50⁰С and even higher, and the humidity of the air does not meet the required. When completing the sale, be sure to remind the client about the need to comply with the rules for storing the drug at home!

Published: 20.02.2013

Much attention is paid to the rational arrangement and equipment of the pharmacy. Pharmaceutical research institutions and departments of higher educational institutions were involved in solving this problem and are currently continuing to work fruitfully.

The pharmacy should be arranged and equipped in such a way that it guarantees: the correct preparation and dispensing of medicines, conditions for high labor productivity of pharmacy workers, compliance with the necessary sanitary and hygienic standards in the premises and at each workplace, proper storage of medicines and the necessary cultural environment for pharmacy visitors.

For the better implementation of the assigned tasks, certain departments are organized in pharmacies:

Stocks;

Prescription and production;

Finished medicines;

OTC (manual sale).

The dimensions of the premises in accordance with the volume of work of the pharmacy are determined by special standards approved by the Ministry of Health.

It is very important for the productive work of the pharmacy the correct location and relationship between the pharmacy premises. All pharmacy premises must be dry and meet sanitary and hygienic requirements.

Pharmacies usually consist of the following rooms:

Reception(waiting for visitors). In the reception room of the pharmacy, ordinary furniture for visitors is placed; showcases with samples of medicines, exhibitions from health education and a hand-selling department equipped with counters and glass cabinets.

prescription- this is a room or part of the room, separated from the reception by a glass partition, in which there should be windows designed for receiving prescriptions and dispensing prepared drugs, a table for a pharmacist-technologist (reciper) and rotating units with shelves and drawers for drugs prepared for holidays.

Assistant- this is a room intended for the preparation of medicines, usually isolated from other rooms. It is equipped with special assistant tables with turntables, on which the most popular medicines are placed.

In large pharmacies, assistant tables are specially equipped, some of which serve only for the preparation of ointments, others for powders, others for liquids, etc. Tables adapted for the preparation of liquid medicines are equipped with burette systems and pipette sets.

The assistant's room contains cabinets for storing small amounts of poisonous and potent medicinal substances.

Sterilization and aseptic unit- This is a special room for the preparation of sterile and aseptic medicines. Usually this block consists of a sterilization room, a vestibule and an aseptic room. If there is no required number of rooms, this block can be placed in one room.

Koktory- this is a room in which water extracts (infusions, decoctions) are prepared, purified water is obtained, and other technological operations related to heating are carried out. The koktory is equipped with infunding or distillation-infunding apparatuses, a distillation cube.

material room- This is a room designed to store stocks of medicines and other sanitary and hygienic items. Equipped with special material cabinets.

washing- This is a special room designed for washing dishes, various appliances. It has cold and hot water, as well as special devices for washing dishes. Equipped with cabinets for drying and storing clean dishes.

Basement- this is a room where stocks of medicines are stored, which must be stored in a cool and dark place. Equipped with shelving and cabinets. For the storage of flammable substances, a refractory concrete storage with iron doors is provided.

In addition to these rooms, the pharmacy should have: a manager's office, a room for a pharmacist on duty, a control and analytical room or a table, a staff room, a first aid room, and a filling room. In small pharmacies, it is possible to combine departments in one room.

2. All premises of the pharmacy facility must be combined into a single block, isolated from other facilities. It is allowed to enter the pharmacy facility through the premises of another organization.
3. The area of ​​the pharmacy facility must be sufficient for the implementation of pharmaceutical activities, taking into account its type and volume.
4. On the premises of pharmacy facilities, it is not allowed to place units that are not functionally related to the implementation of the activities provided for in Article 73 of this Chapter.
5. Pharmacy facilities, depending on the type, must include at least the following premises:
a) for a pharmacy: a trading floor, a room for acceptance and unpacking, a material room, a room for staff, a room for administration, a bathroom. A pharmacy that also manufactures medicines must have, in addition to the following: a room for the manufacture of medicines (assistant), washing, distillation. For pharmacies involved in the manufacture of sterile dosage forms, it is also necessary to have a sterilization room, which can be combined with a distillation room, and an aseptic box / block;
b) for a pharmacy: a trading floor, a room or area for acceptance and unpacking, for a material room and for staff. Pharmacy workers should be provided with access to the use of a bathroom, which can be located in the building where the pharmacy is located;
c) for a pharmacy kiosk: a single room for one workplace without a trading floor. Pharmacy workers should be provided with access to the use of a bathroom, which may be located in the building where the pharmacy kiosk is located;
d) for a hospital and interhospital pharmacy: a room (area) for acceptance and unpacking, a material room, a room (area) for vacation, a room for staff, a room for administration, a bathroom. A pharmacy that also manufactures medicinal products must have, in addition to the listed ones: premises for the manufacture of medicinal products (assistant), washing, distillation. For pharmacies of hospital and interhospital pharmacies engaged in the manufacture of sterile dosage forms, it is also necessary to have a sterilization room, which can be combined with a distillation one, and an aseptic box / block.
6. The internal surfaces of walls, ceilings, floors of pharmacy facilities should allow wet cleaning using disinfectants. The decoration of administrative and amenity premises of pharmacy facilities allows the use of wallpaper, carpets, parquet, oil paints, etc.
7. Pharmacy facilities must be equipped with equipment corresponding to the volume and nature of the pharmaceutical activities carried out.
Premises for the storage of medicinal products must be equipped with equipment to ensure their proper storage, taking into account the physico-chemical, pharmacological and toxicological properties within the established shelf life.

Work on the reception of goods of the pharmacy assortment Tasks and functions of the inventory department : Stock department features: 1) determination of the current need for medicines and medical devices 2) timely submission of orders for them 3) acceptance of goods in terms of quantity and quality 4) ensuring proper storage 5) organization of subject-quantitative accounting 6) laboratory and packaging work 7) release of goods other departments, separate structural divisions, medical institutions Placement and equipment of material rooms: AT material rooms - goods are placed, the storage conditions of which do not require a low temperature. The material room is located separately and is equipped with special shelves and cabinets for storing goods. The penetration of sunlight and high humidity is not allowed. A room is located in the inventory department. The inventory department includes the following premises: · unpacking; pantries (for storing drugs, finished medicines, thermolabile, mineral waters, containers, utensils, auxiliary materials, medicinal plant materials, dressings); · Premises for maintenance of medical institutions (for receiving and processing orders, forwarding). In the stock department, laboratory (preparation of concentrates for burette units, semi-finished products and finished drugs for intra-pharmacy preparation - intra-pharmacy preparation) and packaging work can be carried out. ). They store medicines in material cabinets and safes, and medical products in cabinets and on shelves. Storage of medicines is carried out taking into account the possibility of their location. At the same time, systematization is carried out according to pharmacological groups, aggregate state (liquid separately from loose, gaseous, etc.), the nature of dosage forms, physico-chemical properties, belonging to the lists. Poisonous medicines belonging to List A, regardless of the dosage form (with the exception of especially toxic ones), are stored in isolation, in metal cabinets specially allocated for this purpose under lock and key. Narcotic medicines are stored only in safes. On the inside of the doors of the safe and the cabinet in which medicines of list A are stored, the inscription “Venena” is made, and on the inside of the doors of the cabinet in which medicines of list B are stored, the inscription “Heroica” and a list of poisonous, potent medicines indicating higher single and daily doses. The inscriptions on the stem-glasses in which poisonous drugs are stored are written in Latin in white letters on a black background, and on the stem-glasses containing potent drugs, in red letters on a white background; in both cases, the highest single and daily doses are indicated on the barbells. Metal bars are made on the windows of the material rooms, in which poisonous, narcotic drugs are stored, and the doors are upholstered with iron. After work is completed, the doors are locked and sealed. Material rooms and safes in which narcotic medicines are stored have a security light and sound alarm. The stock of poisonous and narcotic drugs does not exceed the monthly requirement. The stock department is headed by the head and his deputies. In addition, pharmacists-technologists and packers can work in the department. Workplace of a pharmacist in the stock department: The workplace of a pharmacist dressed in stocks contains: a chair, a tabletop or a table with small cabinets for storing inventory. Availability of a computer, line machine, printer. The inventory includes: boxes and cabinets for storing goods, wheelchairs, baskets for transferring goods. For packaging goods: clerical knife, adhesive tape Normative base: The work of a pharmacist in the stock department is regulated by: -Order of the Ministry of Health of Russia dated November 13, 1996 No. 377 “On approval of requirements for organizing storage in pharmacies of various groups of medicines and medical products”; · -Order of the Ministry of Health of Russia dated July 16, 1997 No. 214 “On Quality Control of Medicines Manufactured in Pharmacy Organizations (Pharmacy Stores)”; - order of the Ministry of Health of Russia dated 05.11.1997 No. 318 “On Approval of the Instruction on the Procedure for Storage and Handling in Pharmaceutical (Pharmacy) Organizations with Medicines and Medical Devices Possessing Flammable and Explosive Properties”; · -Order of the Ministry of Health and Social Development of Russia dated 12.11.1997 No. 330 “On measures to improve the accounting, storage, prescribing and use of narcotic drugs and psychotropic substances” (as amended and supplemented); · -order of the Ministry of Health of Russia dated March 15, 2002 No. 80 “On approval of the industry standard “Rules for the wholesale trade of medicines. Basic Provisions” (as amended and added). · Work on receiving goods pharmacy assortment occurred in both pharmacies and almost daily. The main task was to accept the goods from the supplier as soon as possible, check them for quality and quantity (instruction. N P-6 of June 15, 1965 for quantity and instruction. N P-7 of April 25, 1966 for quality). Acceptance of goods takes place in several stages. At the first stage, the pharmacist checks the quantity of goods in places, then checks the documentation, stamps the pharmacy and personal signature, and then releases the courier. The second stage is to check the goods in terms of quantity and immediately quality. The quantity is checked against the invoice data, as well as the series indicated on the product and in the documents. After checking, the goods are cured, hatched and sent to the material room. Hatching is carried out throughout the product, the necessary product is sent to the trading floor with price tags. Goods that need to be stored in a cool place are sent to the refrigerator. Examples of accompanying documents: - waybill (Appendix No. 4) - invoice - price negotiation protocol - certificate (declaration. Reg.ud, passport) of conformity (Appendix No. 4) - packing list Books of accounting for incoming goods, acceptance of goods. Acceptance of goods and containers must be carried out in strict accordance with GOSTs, technical conditions, special delivery conditions, etc. in terms of the number of pieces and gross weight, which is noted in the primary documents. Acceptance of goods by the number of units and net weight is carried out on the spot (at the pharmacy) with the involvement of a representative of the supplier (before opening the container). At the same time, a note is made about the start and end time of receiving goods. If discrepancies are found between the actual quantity and quality of the received valuables and the corresponding data indicated in the supplier's accompanying documents, the head of the pharmacy, and in his absence, the first deputy, creates a commission that draws up an act in the form N 2-AP. When accepting goods delivered in bulk, the financially responsible persons on all copies of the invoice returned to the driver or freight forwarder, confirming the fact of acceptance of the goods, affix a stamp in the form N 1-AP, certify with their signature, and in the absence of a stamp put the seal of the pharmacy. Upon delivery by the supplier to the pharmacy of goods packed in boxes, containers, bags or other types of packaging, sealed and sealed, the financially responsible persons on all copies of the invoices confirm the fact of acceptance by the number of places with their signatures and seals. In the event of a discrepancy (if any) between the actual availability of goods and the invoice data, a note is made about the start and end times of goods acceptance. When the supplier delivers goods to the pharmacy, in addition to checking the gross weight and the number of places, the pharmacy representative may require opening the container and checking the net weight, the number of trade units in each place. In the event of a shortage or damage to the cargo accepted by the pharmacy at the railway station, water pier or airport, the cargo receiver must require the administration of the transport organization to draw up a commercial act. At the same time, it is necessary, as in the case of doubts about the usefulness of the arrived cargo (due to soaking, a long stay on the way, etc.), to open the corresponding shipping items of the cargo to check its contents, identify the actual amount of damage and include all deviations associated with specified cases, in a commercial act. All goods received by the pharmacy are credited and recorded in the register of receipt of goods by groups in the form N 5-AP. At the end of the month, the results of the magazine are calculated at two prices (retail and wholesale). Accounting for the movement of goods (including prescription and material utensils, boxes) is carried out in a pharmacy only in value terms at the sale value. Medicines subject to subject-quantitative accounting are recorded separately in quantitative terms in the register of poisonous, narcotic, scarce medicines and ethyl alcohol in the form N 10-AP. The head of the pharmacy keeps records of goods in the register (sheet), which is also a commodity report in the form N 25-AP. The report is drawn up in two copies. The received material values, according to which an act of combat, marriage and damage was drawn up, are credited to the total of the pharmacy account in the form N 72-AP on account 004 "Inventory accepted for safekeeping". Organization of storage of pharmacy goods: Requirements for the arrangement and operation of storage facilities: In order to ensure the high quality and safety of medicines and medical products in pharmacies, to create safe working conditions when working with them, there are instructions for organizing the storage of various groups of medicines and medical products in pharmacies storage of pharmacy warehouses and pharmacies must meet all the requirements of the current regulatory and technical documentation SNiP, guidelines, regulatory internal documentation, etc. Medicines, medical products in storage rooms must be placed taking into account the fullest use of the area, creating the best working conditions for warehouse and pharmacy workers, the possibility of using mechanization and ensuring pharmaceutical order. Medicinal products, medical products should be placed on shelves, in cabinets, and, if necessary, on the floor, having previously placed a pallet, a pallet, a special plate, etc. The arrangement, operation and equipment of storage rooms should ensure the safety of medicines and medical products. Storage rooms in accordance with established standards are provided with security and fire-fighting equipment. In the storage rooms, certain temperature and humidity must be maintained, the frequency of checks, which should be carried out at least 1 time per day. To monitor these parameters, warehouses must be provided with thermometers and hygrometers, which are fixed on the internal walls of the storage away from heating devices at a height of 1.5-1.7 m from the floor and at a distance of at least 3 m from the doors. Each department should have a record of temperature and relative humidity. In order to maintain clean air, storage rooms in accordance with the current regulatory and technical documentation (SNiP, guidelines, etc.) should be equipped with mechanically driven supply and exhaust ventilation. If it is not possible to equip storage rooms with supply and exhaust ventilation, it is recommended to equip window vents, transoms, second lattice doors, etc. Pharmacy warehouses and pharmacies are equipped with central heating devices. It is not allowed to heat the premises with gas appliances with an open flame or electric heaters with an open electric coil. Storage rooms must be provided with the necessary number of racks, cabinets, pallets, underwares, etc. The racks are installed in such a way that they are at a distance of 0.6-0.7 m from the outer walls, at least 0.5 m from the ceiling, and at least 0.25 m from the floor. The racks in relation to the windows should be located so that the aisles are illuminated, and the distance between the racks is at least 0.75 m, providing free access to the goods. Premises of pharmacy warehouses and pharmacies must be kept clean; the floors of the premises should be periodically (but at least once a day) cleaned with a wet method using approved detergents. Basic principles of storage. Medicines, medical products in storage rooms must be placed taking into account the fullest use of the area, creating the best working conditions for warehouse and pharmacy workers, the possibility of using mechanization and ensuring pharmaceutical order. Medicines, medical products should be placed on racks, in cabinets, and if necessary on the floor, after placing a pallet, a pallet, a special plate, etc. Medicines are placed separately in storage rooms: - in strict accordance with toxicological groups; - poisonous, narcotic and potent drugs must be stored in accordance with applicable requirements; - according to pharmacological groups; - depending on the method of application (internal, external); - medicinal substances "angro" in accordance with the state of aggregation (liquid separately from loose, gaseous, etc.); - in accordance with the physico-chemical properties of drugs and the influence of various environmental factors; - taking into account the established shelf life for drugs with limited shelf life; - taking into account the nature of the various dosage forms. Medical products should be stored separately by groups: - rubber products; - plastic products; - dressings and auxiliary materials; - products of medical equipment. During storage, a continuous visual inspection of the state of the container, external changes in medicines and medical devices should be carried out at least once a month. If the container is damaged, it is necessary to immediately eliminate its defects or transfer the contents to another container. In case of external changes in medicines, their quality is controlled in accordance with the requirements of the State Pharmacopoeia (GF) and other regulatory and technical documents (NTD) and their suitability for use is determined in the prescribed manner. In storage rooms, as well as on the territory of the warehouse, it is necessary to systematically carry out measures to combat rodents, insects and other pests. Requirements for the storage of various groups of medicines and medical devices. All medicines, depending on the physical and physico-chemical properties, the impact on them of various environmental factors, are divided into: - requiring protection from light, - requiring protection from moisture, - requiring protection against volatilization and drying, - requiring protection against exposure to elevated temperatures, - requiring protection from low temperatures, - requiring protection from environmental gases, odorous, coloring and a separate group of medicines - disinfectants. Features of storage of medicines requiring protection from light: Among the medicines that require protection from light include: antibiotics, herbal preparations (tinctures, extracts, concentrates from plant materials), herbal medicinal raw materials, organ preparations, vitamins and vitamin preparations; corticosteroids, essential oils, fatty oils, coated preparations, salts of hydroiodic and hydrobromic acids, halogenated compounds, nitro and nitroso compounds, nitrates, nitrites, amino and admido compounds, phenolic compounds, phenothiazine derivatives. Medicinal products that require protection from light should be stored in containers made of light-protective materials (orange glass glass containers, metal containers, packaging made of aluminum foil or polymeric materials painted black, brown or orange), in a dark room or cabinets painted painted inside with black paint with tight-fitting doors, or in tight-fitting boxes with tight-fitting lids. To store medicinal substances that are especially sensitive to light (silver nitrate, prozerin, etc.), glass containers are pasted over with black opaque paper. Features of storage of medicines requiring protection from moisture. Among the drugs that require protection from moisture include: hygroscopic substances and preparations (for example, potassium acetate, dry extracts, herbal medicinal raw materials, hydrolyzing substances, salts of nitric, nitrous, hydrohalic and phosphoric acids, salts of alkaloids, sodium organometallic compounds, glucosides, antibiotics, enzymes, dry organ preparations), medicinal substances characterized by FS as "very easily soluble in water", as well as medicinal substances, the moisture content of which should not exceed the limit established by the Global Fund and other NTDs, and medicinal substances oxidized by atmospheric oxygen . Medicines that require protection from exposure to atmospheric water vapor should be stored in a cool place, in a tightly closed container made of materials impervious to water vapor (glass, metal, aluminum foil, thick-walled plastic containers). Medicinal products with pronounced hygroscopic properties should be stored in a dry room in a glass container with a sealed closure, filled with paraffin on top. When closing containers with such medicinal substances, it is necessary to carefully wipe the throat and cork. Features of storage of medicines requiring protection from volatilization and drying. Among the drugs that require protection from volatilization include: - actually volatile substances; - medicines containing a volatile solvent (alcohol tinctures, liquid alcohol concentrates, thick extracts); - solutions and mixtures of volatile substances (essential oils, solutions of ammonia, formaldehyde, hydrogen chloride over 13%, carbolic acid, ethyl alcohol of various concentrations, etc.); - medicinal plant materials containing essential oils; - medicines containing water of crystallization - crystalline hydrates; - medicinal substances that decompose with the formation of volatile products (iodoform, hydrogen peroxide, chloramine B, sodium bicarbonate); - medicinal substances with the lower limit of moisture content established by regulatory and technical documentation (magnesium sulfate, sodium paraaminosalicylate, sodium sulfate, etc.). Medicines that require protection from volatilization and drying should be stored in a cool place, in a hermetically sealed container made of materials impervious to volatile substances (glass, metal, aluminum foil). The use of polymer containers, packaging and capping is allowed in accordance with the Global Fund and other NTD. Features of storage of medicinal products requiring protection from exposure to elevated temperatures. Medicines that require protection from exposure to elevated temperatures include: - a group of medicinal substances that require protection from volatilization and drying; - fusible substances; - immunobiological preparations; - antibiotics; - organ preparations; - hormonal preparations; - vitamins and vitamin preparations; - preparations containing glycosides; - medical fats and oils; - fat-based ointments and other substances. Medicines that require protection from exposure to elevated temperatures should be stored at room (18-20 degrees C), cool (or cold - 12-15 degrees C) temperature. In some cases, a lower storage temperature is required (for example, for ATP - 3-5 degrees C), which should be indicated on the label or in the instructions for use of the drug. Immunobiological preparations should be stored in industrial packaging separately by name, at the temperature indicated for each name on the label or in the instructions for use. Immunobiological preparations of the same name are stored in batches, taking into account their expiration date. It is necessary to strictly comply with the requirements for the timely replacement of sera and vaccines in an irreducible supply with freshly prepared ones. Immunobiological preparations should be visually inspected during storage at least once a month. Antibiotics should be stored in commercial containers at room temperature unless otherwise indicated on the labels. Organic preparations should be stored in a dark, cool and dry place at a temperature of 0 + 15 degrees. C, unless otherwise indicated on labels or instructions for use. Burov's liquid needs to be stored in a cool place. When cloudy, the solution is filtered and checked for compliance with all the requirements of the Global Fund. Solution opalescence is allowed. Features of storage of medicines requiring protection from exposure to low temperatures. Among the drugs that require protection from exposure to low temperatures are those whose physicochemical state changes after freezing and is not restored upon subsequent warming to room temperature (40% formaldehyde solution, insulin solutions, etc.). 40% solution of formaldehyde (formalin) should be stored at a temperature not lower than +9 degrees C. When a precipitate appears, the solution is kept at room temperature, then the solution is carefully drained and used in accordance with the actual formaldehyde content. Glacial acetic acid should be stored at a temperature not lower than +9 degrees C. When a precipitate appears, the acid is kept at room temperature until the precipitate dissolves. If the precipitate does not dissolve, the liquid part of the acid is drained and used in accordance with the actual content of acetic acid in the preparation. Medical fatty oils are required to be stored at a temperature ranging from +4 to +12 degrees C. When a precipitate appears, they are kept at room temperature, decanted and checked for compliance with all the requirements of the Global Fund. When a precipitate appears, oils are not used in medical practice. Freezing of insulin preparations is unacceptable. Features of storage of odorous and coloring medicines and parapharmaceutical products. The group of odorous drugs consists of both volatile and practically non-volatile drugs with a strong odor. The group of coloring drugs includes substances, their solutions, mixtures, preparations, etc., leaving a colored mark on containers, closures, equipment and other items that is not washed off by ordinary sanitary and hygienic treatment (brilliant green, methylene blue, indigo carmine and etc.). Odorous medicines should be stored separately in a hermetically sealed container, impervious to smell, separately by name. Medicinal products and parapharmaceutical products should be stored separately. Coloring medicines must be stored in a special cabinet in a tightly closed container, separately by name. To work with dyes for each item, it is necessary to allocate special scales, a mortar, a spatula and other equipment. Features of storage of finished medicines Storage of finished medicinal products must meet the requirements of the Global Fund and all the general requirements of these instructions for the storage of medicinal products, taking into account the properties of the ingredients that make up their composition. All finished medicinal products must be packed and installed in the original packaging with the label (marking) facing out. On racks, shelves, cabinets, a rack card is attached, which indicates the name of the medicine, series, expiration date, quantity. The card is printed on thick paper and started for each newly received series to control its timely implementation. In addition, the department should have a file on expiration dates. Drugs that are subject to re-control and expired are stored separately from others until the results of the analysis are received. Tablets and dragees are stored separately from other medicines in their original packaging, which protects them from external influences and is designed for distribution to individual patients and medical institutions. Storage of tablets and dragees should be carried out in a dry and, if necessary, in a place protected from light. Dosage forms for injections should be stored in a cool, dark place in a separate cabinet or insulated room, and taking into account the characteristics of the container (fragility), unless otherwise indicated on the package. Liquid dosage forms (syrups, tinctures) should be stored in a hermetically sealed container filled to the top in a cool, dark place. Precipitates during storage of tinctures are filtered out, and if the filtered tincture, after quality control, meets the established requirements of the Global Fund, it is considered suitable for use. Plasma-substituting (and detoxification) solutions are stored in isolation at a temperature ranging from 0 degrees C to 40 degrees C in a place protected from light. In some cases, freezing of the solution is allowed, if this does not affect the quality of the drug. The extracts are stored in a glass container sealed with a screw cap and a cork with a gasket in a place protected from light. Liquid and thick extracts are stored at a temperature of 12-15 degrees C. The precipitates that form in liquid extracts over time are filtered out and, if the extracts, after quality control, meet the established requirements of the Global Fund, they are considered suitable for use. Ointments, liniments are stored in a cool, dark place in a tightly closed container. If necessary, storage conditions are combined depending on the properties of the incoming ingredients. For example, preparations containing volatile and heat-labile substances are stored at a temperature not exceeding 10 degrees C. Suppositories should be stored in a dry, cool, dark place. Storage of most medicines in aerosol packages should be carried out at a temperature of +3 to +20 degrees C. In a dry, dark place, away from fire and heaters. Aerosol packages should be protected from shock and mechanical damage. Regulatory framework for the storage of lek. funds and medical devices: - ORDER of the Ministry of Health of the Russian Federation dated August 23, 2010 N 706n; “On approval of the rules for the storage of medicines” - ORDER of the Ministry of Health of the Russian Federation of November 13, 1996 N 377 (as amended by the Order of the Ministry of Health and Social Development of the Russian Federation of August 23, 2010 N 706n) “On approval of instructions for organizing the storage of various groups of medicinal and medical products in pharmacies ". Registration of labels in the OZ: The procedure for the formation of free retail prices for lek funds: These issues are considered in the Procedure for setting prices for medicines and medical products (separate issues) (Appendix N 5 to the Order of the Prime Minister of the Government of Moscow dated 06.10.97 N 1093-RP). In cases where the terms of the contract between Russian companies provide that payment will be made as the medicines are sold and their cost is indicated in foreign currency, the trade markup should be applied to the price converted into rubles at the exchange rate of the Central Bank of the Russian Federation on the date of receipt of medicines on buyer's warehouse. If the contract provides that the supplier of medicines provides the consumer with a percentage discount from the free wholesale (selling) price of medicines and indicates this in the payment document, the wholesale or trade markup is applied to the price reduced by the amount of this discount. In cases where the supplier indicates to the consumer in the payment document that out of the total number of supplied medicines, a part of certain drugs is dispensed in the form of a discount in kind, such a discount should be considered by analogy with a percentage discount. If the contract provides that, as a result of joint cooperation, the supplier, in addition to the main supply, dispenses medicines of other names without payment, their further sale is carried out with the addition of a wholesale or trade markup to the prices indicated by the supplier in the invoice for the release of goods, depending on the type of sale of the goods. Income from the sale of medicines received free of charge is directed to the results of financial and economic activities. When a pharmaceutical enterprise manufactures medicines from customer-supplied raw materials with subsequent presentation of the costs of their production to the owner of raw materials, free wholesale (selling) prices for domestic finished products can be formed by the owner of raw materials based on their cost, as well as supply and demand in the wholesale market. At the same time, all costs for the production of such products should be reflected in the balance sheet of the owner of the finished product. An organization or an entrepreneur who has supplied raw materials to an organization licensed to manufacture medical products and has entered into an agreement on joint activities with a manufacturing organization, which indicates that the owner of the product ready for sale is the owner of the raw materials, have the right to independently form selling wholesale prices. Pharmacy enterprises (firms) engaged in wholesale trading activities and containing pharmacies on their balance sheet (without the right of a legal entity), but having licenses for the right to retail, subject to separate accounting for the wholesale and retail link, form retail prices for medicines and medical products using two allowances simultaneously (wholesale and retail). Prices for medicines manufactured by pharmacies are formed based on the cost of ingredients at retail prices, containers and manufacturing tariffs. Tariffs for the manufacture of medicines are free and are determined by pharmacies. The exchange of medicines and medical devices is carried out in the following order: - in the retail sector - at retail prices formed by pharmacies, taking into account the trade markup; - in the wholesale link - at wholesale prices formed by the wholesale link, taking into account the trade markup. The exchange of imported medicines and medical products purchased by wholesale organizations at the expense of their own foreign exchange funds is carried out at selling prices formed in accordance with the current regulatory documents. The further sale of the goods received under the exchange is carried out at the exchange price without the application of any trade markups. Setting up price tags: The design of price tags is regulated by Decree of the Government of the Russian Federation of January 19, 1998 N 55 (as amended on October 4, 2012) "On approval of the Rules for the sale of certain types of goods, a list of durable goods that are not subject to the buyer's requirement to provide him free of charge for the period of repair or replacement of a similar goods, and a list of non-food products of good quality that cannot be returned or exchanged for a similar product of a different size, shape, dimension, style, color or configuration" (as amended and supplemented, effective from 01.01.2013) According to the resolution "seller is obliged to ensure the availability of uniform and clearly defined price tags for the goods sold, indicating the name of the product, its grade, price per weight or unit of goods, the signature of the financially responsible person or the seal of the organization, the date of issue of the price tag.

When planning the premises of a pharmacy, one should be guided by the type of activity and the volume of work of the organization. At the same time, it is important to take into account not only your own ideas that allow you to increase turnover, but also the mandatory requirements for pharmacy premises necessary to obtain a pharmaceutical license:

The area of ​​the pharmacy must be at least 80 m2

The minimum composition of the premises should include:

  • Trading floor with an area of ​​at least 20 m2;
  • Premises (in a production pharmacy) for the manufacture of medicines of at least 15 m2 and distilled water of at least 5 m2;
  • Washing room not less than 5 m2;
  • Premises for storage of medicines not less than 36 m2;
  • Receiving room;
  • Office of the head and accountant;
  • Room for staff at least 8 m2;
  • Wardrobe;
  • Bathroom.

No one forbids increasing the area of ​​\u200b\u200bthe room, but it is impossible to reduce it. Let us consider in more detail the composition and purpose of pharmacy premises.

Shopping room. His appointment- customer service. Information stands are placed on the trading floor, where the buyer can familiarize himself with the license, obtain data on reception hours, the procedure for servicing disabled people and participants in the Second World War, and regulatory and supervisory authorities. There is also a book of complaints and suggestions.

Planning a sales floor is not an easy task, for which you need to have certain marketing knowledge. So, according to statistics, only 15% of the retail space falls on the checkout area, the rest - on the hall. If the area of ​​the trading floor has too many free zones, it means that it is spent inefficiently, and this mainly concerns the center and perimeter, with the exception of the zone on the left side immediately at the entrance to the pharmacy.

Medicine preparation room equipped with various equipment for working with medicines - mixing, filtering, packaging, packaging, direct manufacturing. In this room, in addition to equipment, it is necessary to install pharmacy furniture and devices for measuring weight and volume, as well as reagents for chemical control of manufactured drugs. There are also safes for storing potent, narcotic, poisonous drugs and ethyl alcohol.


The premises for the preparation of medicines must be equipped with workplaces for employees. In a production pharmacy, the area of ​​​​this room goes beyond the regulatory requirements and may have several jobs for the manufacture and quality control of drugs.

It must be understood that sanitary and hygienic conditions are especially important for a production pharmacy, which is why it is necessary to ensure complete isolation from polluted outside air. In these pharmacies, it is necessary not only to comply with regulatory requirements (isolated entrance), but also to install additional air purification systems in the ventilation system. It is desirable to exclude the presence of extraneous noise from the street so that employees can fully concentrate on their work. In passing, it is necessary to mention the entrances to the pharmacy - two doors for pharmacy organizations of categories 1 and 2, it is double-winged with a width of at least 0.9 m for pharmacies of categories 3 and 4, as well as a separate entrance for receiving goods and a service entrance with a width of at least 1.2 m. Be sure to equip the vestibule with a thermal curtain.

Room for the production of distilled water required only in industrial pharmacies. Here are located the apparatus for obtaining distillate and containers for its storage. The presence of foreign objects and the performance of other work not related to the distillation of water is unacceptable! It is allowed to obtain distilled water by direct distillation, reverse osmosis, ion exchange, or a combination of these methods.


In the washing room laboratory glassware used for the preparation of medicines is washed, therefore this room can also be classified as a production room. The basic requirements for equipment are set out in the documentation on the sanitary regime of the pharmacy. Sinks for washing dishes should be marked depending on its type: for eye drops and injection solutions, for intravenous and external dosage forms.


Storage room for medicines is available in any pharmacy, while it must necessarily comply with regulatory requirements and be equipped with the necessary equipment and furniture (lockers, racks, pallets), storage areas for medicinal herbs. The pharmacy must ensure the safety of drugs, preserve the original properties of drugs, maintaining the desired level of temperature and humidity, otherwise they will not only lose their qualities, but can also become dangerous. A complete list of requirements is specified in the Order of the Ministry of Health N 706n dated August 23, 2010 "On approval of the Rules for the storage of medicines."


All medicinal products are stored in conditions appropriate to their

  • physical and chemical properties;
  • pharmacological group;
  • method of application;
  • state of aggregation

The surfaces of the room must be made of materials that are resistant to disinfectants. Rooms and safes with narcotic and especially poisonous drugs must have an alarm system, there must be metal bars on the windows.

staff room designed for employee recreation. Since it is forbidden to eat at the workplace, and a private dining room is a luxury, most often employees also have lunch in the staff room. Therefore, it must be equipped with the necessary equipment for this (refrigerator, microwave, electric kettle). It is strictly forbidden to store food in refrigerators for storing medicines!


The area of ​​the dressing room should correspond to the number of staff and is equipped with cabinets for storing outerwear and shoes.

Office of the head and accountant is allocated depending on the possibility - the larger the pharmacy, the more senior managers there, the larger the area of ​​\u200b\u200bthe premises. In small pharmacy kiosks and pharmacy points, most often there is one office for the manager and accountant.


The pharmacy must necessarily include a bathroom, and if the organization is located in a shopping center, employees must be provided with unhindered access to the common bathroom. Rooms should be planned based on their purpose.

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