Treatment of influenza and SARS, urogenital infections with Genferon light (instruction, use, dosage, indications, contraindications, action). Genferon light suppositories - instructions for use Release form, composition and packaging

Viral diseases lie in wait for a person everywhere. Neither children nor adults can resist the new strain of the virus. Viruses are especially active in the autumn-winter period, when even a healthy person's immunity decreases. With a viral infection of the body, it's time to remember the effective drug Genferon Light. It will help get rid of not only the classic cold caused by SARS, but is able to overcome more serious viral diseases, as it effectively improves both general and local immunity.

Basic information about the drug and composition

Candles Genferon Light are available in two dosages:

  • for children under 7 years old- 125 thousand units of interferon;
  • for children over 7 years old- 250 thousand units of interferon.

The basis of the drug contains two active active ingredients - taurine and recombinant human interferon-alpha-2b(hereinafter simply interferon), as well as auxiliary components, the predominant of which is hard fat.

Important! A prerequisite for maintaining the biological activity of interferon is storage in the refrigerator. If the drug is stored at room temperature (up to 25 degrees Celsius), then it must be used within a month.

Interferon in the composition of the drug is not obtained from human blood, but by genetic engineering. It is synthesized by a bacterium into which a gene is introduced that is responsible for the production of human interferon. Therefore, the risk of contracting dangerous types of diseases transmitted through the blood or the risk of allergies is minimized.

Mechanism of action


On the other hand, acting as the strongest antioxidant, taurine binds to oxygen, which is necessary for the development of oxidative processes. As a result, excess oxygen in the tissues disappears, and inflammatory processes do not worsen. Also, thanks to taurine, the biological activity of interferon is preserved, which protects the body from adverse effects.

Interferon has the following types of effects:

  • antiviral:
  • antibacterial;
  • immunomodulatory.

Unique in its characteristics, taurine is capable of:

  • normalize metabolism;
  • accelerate the regeneration of tissues affected by destructive processes;
  • produce an antioxidant effect;
  • enhance the biological activity of interferon.

Instructions for use of children's candles Genferon light

An indication for the rectal administration of Genferon Light suppositories in children is the treatment of acute respiratory viral infections and other infectious diseases of viral origin, including intestinal infections (rotavirus is the most common). If necessary, the remedy is successfully combined with antibiotics, sometimes even enhancing their effect.

Type of diseaseChild's ageDosageMultiplicity of receptionDuration of treatment
SARS and acute viral diseases, including intestinal infectionsUp to 7 years125,000 IU (1 candle)2 times a day. after 12 hours5 days. If necessary, repeat the course after 5 days
Over 7 years old250,000 IU (1 candle)
Viral diseases of a chronic natureUp to 7 years125,000 IU (1 candle)10 days. After completing the course, continue to inject 1 suppository at night every other day for 1-3 months
Over 7 years old250,000 IU (1 candle)

Contraindications and side effects

Like all drugs, Genferon Light suppositories have contraindications, but they are relative. The drug should not be used for those patients who have an individual sensitivity to interferon or taurine.

With the correct use of the drug, there is no negative effect from it, since interferon is not able to adversely affect the formation of the child's immune system. Rather, on the contrary, it is activated and resistance to viruses increases.

Video how to put a candle on a baby

Reviews about the drug

Since Genferon Light is actively used in various fields of medicine, both doctors and patients actively share their opinions about the use of both Genferon Light itself and its analogues. Doctors note that the Genferon Light remedy perfectly fights many viral pathologies that it cannot cope with, for example,. However, doctors warn that you should not get too carried away with Genferon suppositories so that the body does not get used to them, although, according to the manufacturer, the use of suppositories does not affect the body's production of its own interferon. Since the drug is dispensed without a prescription, often even with the appearance of the first runny nose or the first sneeze, patients run for Genferon Light for themselves or their children. Doctors note that the remedy “works best” according to indications, when there really is a need to help your immune system overcome the disease. In this case, doctors actively prescribe Genferon Light, as they are confident in its safety and effectiveness.

Not without attention and Genferon Light in pediatrics. There are a lot of positive reviews when Genferon Light helped children cope with ARVI better than Interferon and Amiksin, which are positioned as full-fledged analogues of the drug. Despite the proximity of Genferon Light to these drugs, it has, according to parents, a greater effect than other antiviral drugs.

As the reviews show, Genferon Light is an effective tool in the fight against viral infection, both in adults and in children.

Content

The drug belongs to the category of immunomodulators and at the same time has an antibacterial effect. The use of the drug is justified in the presence of various inflammatory pathologies caused by a number of pathogenic bacteria. Often, Genferon suppositories are used to treat the organs of the genitourinary tract (for thrush, cystitis, prostatitis, genital herpes), while not only the symptoms of the disease are eliminated, but also the cause of inflammation.

Genferon candles - instructions for use

The drug is an immunomodulatory complex of substances that has an antimicrobial, anti-inflammatory effect. As a rule, Genferon is used to treat diseases of the genitourinary system in men and women. The antiviral effect of the drug extends to a significant group of pathogenic microorganisms - bacteria, viruses, fungi, etc. The immunomodulatory effect of suppositories is manifested due to the activation of immune defense links that ensure the destruction of long-lived bacteria that provoke chronic inflammation.

The components of the drug provide systemic and local action, activating certain elements of the immune system that act in the blood and on the mucous membranes. With rectal administration, a systemic effect is achieved, which makes it possible to treat bacterial, viral diseases of the respiratory system with Genferon or to prevent many other pathologies by activating immune cells and generally strengthening the protective properties of the body.

Compound

The main component of the drug is human interferon alpha 2B, in the preparation it can be in a dosage of 250, 500 thousand or 1,000,000 IU. Other active substances in the composition of the drug are:

  • aminosulfonic acid (0.01 g);
  • benzocaine or anestezin (0.055 g).

Since the active ingredients need a special environment for the fastest penetration into the circulatory system and fixation on the mucous membrane of the vagina or rectum, the basis of the drug is solid fat. All active substances and other auxiliary components are evenly distributed in it, which include:

  • emulsifier T2;
  • dextran 60 thousand;
  • sodium hydrocitrate;
  • macrogol 1500;
  • lemon acid;
  • purified water;
  • polysorbate 80.

Release form

The medication is presented as suppositories for rectal or vaginal use. The shape of the suppositories resembles a white cylinder with a sharp end. The internal structure of the candles is homogeneous, an air rod or a small depression in the form of a funnel is visible in the section. The drug is available in packs of 10 or 5 suppositories, depending on the dose of interferon, it is divided into 3 types:

  • Genferon 250000;
  • Genferon 500000;
  • Genferon 1000000.

Pharmacodynamics and pharmacokinetics

The introduction of suppositories into the rectum ensures close contact of the mucosa with the drug, due to which the active components of rectal suppositories are absorbed into the bloodstream by 80%. The maximum concentration of interferon and other active substances in the blood is observed 5 hours after the use of Genferon. Good absorption of the drug provides both local and systemic therapeutic effects.

With the vaginal use of suppositories, the maximum local therapeutic effect is achieved, which is due to the accumulation of most of the drug in the foci of infection. The mucous membrane of the vagina cannot provide high absorption, therefore, in this case, the penetration of the active substances of Genferon into the blood is minimal. The drug undergoes breakdown into metabolites, after which it is removed in the urine within 12 hours.

Candles Genferon - indications for use

The systemic immunomodulatory drug has a wide spectrum of action: it has found application in the complex therapy of various infections of the genitourinary system in women and men. In addition, Genferon is used as an independent drug, and as part of complex treatment with other medicines and methods. Candles with interferon are indicated for the treatment of HPV and for such diseases:

  • vaginal candidiasis;
  • herpes viruses;
  • chlamydia;
  • mycoplasmosis;
  • candidiasis of the vulva;
  • ureaplasmosis;
  • adnexitis;
  • viral hepatitis;
  • trichomoniasis;
  • erosion of the cervix;
  • bartholinite;
  • vaginosis;
  • cervicitis;
  • gardnerellosis;
  • urethritis;
  • inflammation of the prostate gland;
  • other sexual infections and urogenital diseases.

Contraindications

It is forbidden to use suppositories in case of an allergic reaction or sensitivity to certain components of the medication. In addition, conditional contraindications to the drug, which you should definitely tell your doctor about, are:

  • autoimmune pathologies;
  • early pregnancy (first trimester);
  • children's age (up to 7 years);
  • allergy in the acute stage.

Method of application and dosage

Candles with recombinant interferon are administered vaginally or rectally, depending on the specifics of the disease and the gender of the patient. Genferon completely dissolves, in contact with the mucous membrane of the rectum or vagina, without causing discomfort. With vaginal administration, a more pronounced local effect is achieved, with rectal administration, a systemic effect is provided. The latter type of drug can even be prescribed for the treatment of acute respiratory viral infections or other infectious pathologies of different localization.

Vaginal suppositories Genferon

In gynecology and inflammatory pathologies, until the age of 7 years, the drug is prescribed at a dosage of 125,000 IU. For adults and children over the age of seven, vaginal suppositories are prescribed in an individual dosage, depending on the severity of the disease, its clinical manifestations. For bacterial infections in the urogenital tract, doctors recommend suppositories with a dosage of 250-500 thousand IU once a day. The duration of therapy, as a rule, does not exceed 10 days.

If Genferon is used as a local anesthetic and anti-inflammatory agent for the treatment of cervical erosion or another disease, then in gynecology it is prescribed in the following scheme: 1 suppository of 500 thousand IU at night vaginally and 1,000,000 IU rectally. In a chronic disease, a three-month therapy is prescribed, which involves the introduction of suppositories into the vagina 3 times a week.

Rectal administration

Candles with this use case allow the active substance to enter immediately into the intestines, and then into the blood. Genferon is administered rectally for the most effective treatment of inflammation of various localizations and for the treatment of male genital infections. In the case of protracted infectious processes in women, the drug is administered rectally, 1 suppository every second day for 1-3 months. For the treatment of men, suppositories are prescribed rectally at a dosage of 500 thousand or 1 million IU, while the use pattern remains the same.

Pediatricians prescribe Genferon Light to children, the instruction of which implies the following treatment regimen:

  • with viral infections - 2 suppositories rectally with an interval of 12 hours (therapy lasts 5 days, then a break for 5 days follows and the treatment is repeated);
  • in case of viral chronic infections, Genferon is administered rectally to the child at night every other day (the course is 1-3 months).

Side effects

According to reviews, negative effects on the background of the use of the drug rarely develop. As a rule, they manifest themselves as allergic reactions and are expressed by a burning sensation or itching in the rectum, vagina. Such side effects disappear on their own a few days after the drug is discontinued. If you experience such manifestations, doctors advise reducing the dosage. It is extremely rare for patients who have been prescribed candle treatment to experience such negative effects:

  • chills;
  • headache;
  • myalgia (muscle pain);
  • increased sweat secretion;
  • loss of appetite;
  • joint pain;
  • fatigue;
  • decrease in the number of leukocytes.

Overdose

Cases of an overabundance of the active substances of Genferon in the body and the occurrence of negative consequences associated with this have not been registered to date.

special instructions

The drug has mostly good reviews, which are due to the high efficiency of Genferon. This remedy is often used by people who have been suffering from chronic diseases of the reproductive or urinary systems for a long time. Candles do not affect the nervous system, so during therapy a person can do any work, including those associated with increased concentration.

During pregnancy

The medicine is safe during gestation from 13 to 40 weeks, as well as for lactating women (with the optimal dosage being 250,000 IU). The decision to treat pregnant women with the drug should be made taking into account the expected benefits and possible risks. If the doctor saw the need to use suppositories during lactation, it is better to temporarily transfer the child to artificial nutrition. Treatment with Genferon for women in the early stages of pregnancy (up to 12 weeks) is highly undesirable, since there are no objective data on the effect of the drug on the fetus.

In childhood

Candles are used as an antiviral agent for the treatment of acute respiratory viral infections and inflammation of the genitourinary system. However, the drug for children should be used with caution and only in cases where the expected benefit outweighs the risks. Therapy of the pathology of the genital organs and urinary system in children involves a 10-day course of rectal administration, 1 suppository 2 times a day. At the same time, the use of Genferon must be combined with the intake of a vitamin complex that contains vitamins C and A.

Interaction with antibiotics

The combination of Genferon with drugs that have antibacterial activity, or antiseptics, leads to an increase in the effectiveness of the treatment of infectious and inflammatory pathologies of the genitourinary system. With an increase in temperature after the use of suppositories, a single dose of paracetamol at a dose of 500-1000 mg is recommended.

Alcohol compatibility

The instructions for the medication do not contain information about the consequences of the simultaneous use of Genferon with alcohol. However, since the drug is often prescribed as part of complex therapy, it is worth focusing on the compatibility of other drugs with ethanol. Doctors do not advise combining alcohol with suppositories, since in this case the load on the liver increases (immunomodulators activate metabolism and the removal of decay products from the body, which burdens the organ, and alcohol will add extra work to the liver).

drug interaction

Simultaneous administration of suppositories with vitamins C and E accelerates the action of the active components of the drug. As part of complex treatment, the drug is prescribed with other antimicrobial agents or antibiotics. Genferon goes well with Terzhinan vaginal suppositories containing nystatin and the antibacterial substance neomycin sulfate. This set of drugs is used in gynecology for the treatment of cystitis, thrush, and other pathologies of the genitourinary tract. They combine Genferon with Hexicon to quickly eliminate various infections and in order to increase immunity.

Terms of sale and storage

The medicine is recommended to be stored in the refrigerator at a temperature not lower than 2 degrees and not higher than 8 degrees. Suppositories should be kept away from children. The shelf life of the drug is no more than 2 years from the date of issue.

Analogues

In a pharmacy, you can easily find an analogue of Genferon, which will have a similar composition and have a similar effect, but can vary greatly in price. Recombinant interferon contains such drugs:

  • Kipferon (composition completely similar to Genferon);
  • Viferon (the composition additionally includes vitamin C and E).

Price for Genferon

Suppositories can be bought at a pharmacy or through an online store without a prescription. at the same time, the cost of a medicine can vary greatly, which is associated with the value of the trade margin, transportation costs and other factors. Since the drug is produced only by Biocad, there is no difference between cheaper or more expensive suppositories. The table shows how much the antiviral agent costs.

Video


It is often quite difficult to choose the right drug. In order to make your choice, it is recommended that you familiarize yourself with the basic information about the properties of each medication, take into account the available side effects and contraindications. Below, drugs such as Viferon and Genferon will be analyzed.

With rectal use, interferon is absorbed into the blood, which has a systemic effect on the body: immunomodulatory and antiviral.

Let's figure out which is better - "Viferon" or "Genferon".

Antiviral suppositories "Viferon"

This tool has been produced since 1998 by Feron LLC.

Candles contain, in addition to recombinant interferon alpha-2b, vitamins C and E, which are cell membrane stabilizers and enhance the effect of interferon. The basis of the candle is cocoa butter (it can cause allergic reactions), as well as confectionery fat. The drug is produced in the form of rectal suppositories (150,000, 500,000, 1,000,000, 3,000,000 units), in the form of a gel and ointment. Candles are administered exclusively rectally. If the patient has genitourinary infections, then it is best to use Viferon in the form of a gel for injection into the uterine cervix or into the vagina.

The drug is allowed to be used from birth for the treatment of children.

Dosage

Dosage: children from birth to seven years of age are prescribed suppositories 150,000 IU, patients older than seven and adults - 500,000 IU.

As a prophylactic against influenza and SARS: one suppository once a day for ten to thirty days.

Therapeutic scheme: twice a day, one candle for five to ten days. Then a break is made for five days and, if necessary, a second course can be taken.

Which is better - "Viferon" or "Genferon"? The question is very relevant.

Antiviral suppositories "Genferon"

The drug has been produced since 2005 by JSC "Biocad" in Moscow.

It is produced in the form of suppositories intended for both rectal and vaginal use (this distinguishes them from the drug "Viferon", which is administered exclusively rectally), as well as in the form of a nasal spray. The action of a systemic nature is noted only with rectal use of the agent, since with a similar method of administration, its absorption is carried out by eighty percent. With endonasal and intravaginal application, it is characterized by local influence (in the nose or in the vagina at the site of application, on mucous membranes).

What is better for children - "Genferon" or "Viferon", you can check with your doctor.

What's in the composition?

The preparation contains recombinant interferon alpha-2b, as well as benzocaine and taurine. The latter activates the recovery processes, has an immunostimulating effect and stabilizes the membranes. Benzocaine provides local anesthesia, with intravaginal use it helps to eliminate discomfort and itching, with rectal use, the presence of this component is not important. At the heart of the candle is solid fat.

Which is better - candles "Viferon" or "Genferon light", interesting to many.

"Genferon Light"

There is also a form of release of the drug specifically for children - "Genferon Light" in the form of suppositories that contain interferon in the amount of 125,000 and 250,000 IU. It can be used from birth. If there is no light additive, then Genferon contains interferon in a higher dosage, which is intended for adult patients.

For the prevention and treatment of influenza and SARS, the drug "Genferon Light" is used rectally.

Dosage features: up to the age of seven, suppositories of 125,000 IU are shown, from seven years and adult patients - 250,000 IU.

Scheme for prevention: once a day, one candle for a period of ten to thirty days.

As a remedy: twice a day, one candle for five to ten days.

"Viferon" and "Genferon" - which is better?

These drugs are almost identical preparations, differing only in additional components in their composition and some other properties. In general, both drugs have a similar mechanism of influence, since the main active ingredient in them is recombinant human interferon alpha 2B.

These drugs can be used to treat young patients because they are completely safe. There is only one contraindication to their use - this is the presence of intolerance to any component of suppositories in a person. In practice, it turned out that the manifestation of allergic reactions occurs in rare cases. In principle, the use of the drug is quite easily tolerated by patients. "Genferon" has a slightly larger number of side effects, but they are mild, and therefore most patients simply do not notice the manifestation of negative reactions. But which is better?

Candles "Viferon" and "Genferon" differ from other antiviral agents based on interferon in that they are often used to treat acute respiratory viral infections in children. This is explained by the fact that these drugs have a low dosage, they are easy to use and well tolerated.

"Genferon" is used more often in the treatment of inflammatory processes and infections in the genitourinary tract, because it contains a local anesthetic that quickly eliminates itching and pain.

Pharmacies are often interested in what is better "Kipferon", "Viferon", "Genferon".

These drugs are very rarely used as a remedy that eliminates infections that affect digestion. Viruses in this area are recommended to be treated by other means.

"Viferon" differs from "Genferon" in that it is produced not only in the form of candles, but also in the form of an ointment and gel. Candles "Viferon" are prohibited for vaginal use by women who suffer from urinary tract infections, for these purposes an ointment or gel is usually prescribed. In turn, suppositories "Genferon" can be used not only rectally, but also vaginally.

Consider reviews about what is better for a child "Viferon" or "Genferon Light".

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

medicinal product Genferon is an immunomodulatory agent with antimicrobial activity, which is mainly used for the treatment of inflammatory pathologies of the genitourinary tract in men and women. The antimicrobial activity of Genferon extends to a fairly large group of pathogenic microorganisms - viruses, bacteria, mycoplasmas, fungi and others. Immunomodulatory properties are manifested in the form of activation of immune defense links, which provide effectiveness against long-lived microbes that provoke chronic inflammatory diseases.

Genferon has a systemic and local effect, activating the components of the immune system that act on the mucous membranes and in the blood.

Description

The drug is available in the form of suppositories (candles) for vaginal or rectal administration. Suppository Genferon has the shape of a cylinder with a sharp end, painted white or slightly yellowish. The inner surface of the suppository has a homogeneous structure. Sometimes an air rod or a small funnel-shaped depression is revealed on a suppository incision.

The drug Genferon of any dosage is available in packs of 5 or 10 suppositories by the domestic pharmaceutical company CJSC Biocad.

Release form

Suppositories (candles) Genferon as one of the active substances contain human interferon alpha 2b in various dosages. Depending on the dose of human interferon, the drug is available in three types of suppositories:
1. Genferon 250,000 - contains interferon alpha 2b in the amount of 250,000 IU.
2. Genferon 500,000 - contains interferon alpha 2b in the amount of 500,000 IU.
3. Genferon 1000 000 - contains interferon alpha 2b in the amount of 1000 000 IU.

Different dosages of Genferon are used for a differentiated approach to the treatment of pathologies that occur with different severity, duration, clinical symptoms, etc.

Compound

Suppositories Genferon as active substances contain three main components:
1. Human interferon alfa 2b at 250,000 IU, 500,000 IU, and 1,000,000 IU.
2. Aminosulfonic acid - taurine in the amount of 0.01 g.
3. Local anesthetic - benzocaine or anestezin in the amount of 0.055 g.

Since the active components of the drug need a special medium for rapid penetration into the bloodstream and fixation on the mucous membranes of the vagina or rectum, solid fat was chosen as the optimal substance for this purpose. Active ingredients and other excipients are evenly distributed in solid fat, which ensure penetration into the bloodstream, stabilization in the volume of the suppository, etc. Auxiliary components are exactly the same, and are contained in equal quantities.

So, the auxiliary substances of Genferon are as follows:

  • dextran 60,000;
  • polysorbate 80;
  • emulsifier T2;
  • sodium hydrocitrate;
  • lemon acid;
  • purified water (deionized);
  • solid fat.

Absorption, distribution and excretion from the body

Rectal application of suppositories (candles) Genferon
The introduction of Genferon into the rectum leads to close contact of the drug with the mucosa, rich in blood and lymphatic vessels, due to which the active components are freely absorbed into the blood. When injected into the rectum, approximately 80% of the dose is absorbed into the bloodstream. The maximum concentration of active components in the blood is observed 5 hours after the administration of suppositories. The high degree of absorption of the drug into the blood allows the drug to have not only a local, but also a systemic effect.

Vaginal use of suppositories (candles) Genferon
With the introduction of Genferon into the vagina, a grown local effect is achieved with the accumulation of a large part of the dose in the pathological focus. The mucous membrane of the vagina does not have a high absorption capacity, so the entry of active components into the bloodstream is minimal. Due to this circumstance, when administered vaginally, the drug has mainly a local effect, and only a slight systemic effect. The maximum concentration in the bloodstream and in the focus of inflammation on the mucous membrane is reached, on average, 5 hours after the administration of suppositories.

The drug Genferon is degraded into metabolites in the kidneys, which are excreted in the urine. The time for which half of the dose of the drug Genferon is excreted is called the half-life - T1 / 2. T1 / 2 for Genferon is 12 hours, which necessitates the use of the drug at least twice a day.

Therapeutic effects (principles of treatment)

Genferon is a combination drug - an immunomodulator, which is used primarily for the treatment of chronic inflammatory diseases of the genitourinary tract in men and women. The therapeutic effects are provided by the active substances that make up its composition - interferon alpha 2b, taurine and benzocaine.

Effects of interferon

Recombinant human interferon alfa 2b is obtained by introducing a special gene into the bacterium Escherichia coli, which produces this substance. Human interferon alfa 2b has the following local and systemic effects:
  • antiviral action;
  • antibacterial action;
  • immunomodulatory action;
  • antiproliferative action (stopping the reproduction of pathogenic microorganisms).
Genferon has an antiviral effect by acting on specific enzymes that help stop the reproduction of viruses. In addition to the activation of enzymes, Genferon directly suppresses signals for the reproduction of a viral particle.

The antibacterial effect of the drug is achieved by activating the cells of the immune system, which begin to fight pathogenic bacteria more effectively.

The immunomodulatory effect of the drug Genferon is manifested by enhancing the activity of immunocompetent cells, which directly capture microbial cells, destroy them, and remove them from the body. This effect is called an increase in the activity of the cellular link of immunity, which is provided by T-lymphocytes or, as they are designated, CD8 +. Activated T-lymphocytes quickly destroy pathogenic bacteria and viruses that are in the blood and have penetrated into the cells of the human body. In addition to cells affected by pathogenic microbes, T-lymphocytes recognize and destroy cells that have undergone tumor transformation and can serve as a source of further growth of neoplasms.

In addition to activating T-lymphocytes, Genferon enhances the activity of killer cells (NK cells, CD16+), which are capable of destroying 5-10 times more pathogenic microorganisms compared to lymphocytes. An increase in the activity of killer cells is associated with an increase in the speed and efficiency of phagocytosis processes, which are provided by a massive release of special cells - macrophages living in the tissues of the body.

The second direction of activation of the body's immune defense under the action of the drug Genferon is characterized by increased production of special biological molecules - antibodies directed against pathogenic microorganisms. Antibodies are immunoglobulins, and are produced by special cells - B-lymphocytes, circulating in the blood.

The drug Genferon also increases the production of the histocompatibility complex molecule, which is necessary for identifying the body's own cells and distinguishing them from the structures of pathogenic microbes and cells infected with viruses.

Genferon activates all types of leukocyteslocated on the surface and inside the mucous membranes, which allows you to enhance the immune response and effectively eliminate the pathological focus in the shortest possible time. The components of the drug Genferon enhance the synthesis of immunoglobulin A (IgA) molecules, which provide protection against pathogenic microorganisms on the mucous membranes, and prevent recurrence of inflammation.

The antiproliferative effect of the drug is expressed in the direct suppression of the activity of the genetic apparatus of viruses and chlamydia, which stops the reproduction of the latter.

Effects of taurine

Taurine has a complex effect on the tissues of the human body, causing the following effects:
  • strengthening of metabolic processes;
  • acceleration of tissue repair processes (regeneration);
  • normalizes the properties of cell membranes, increasing the stability and viability of cells;
  • anti-inflammatory property;
  • immunomodulatory effect;
  • antioxidant action associated with the neutralization of free radicals and stopping chain reactions of peroxidation;
  • enhances the activity of interferon alpha 2b.

Effects of benzocaine

Benzocaine is a local anesthetic that is not absorbed into the bloodstream and does not have a systemic effect. The main effects of benzocaine:
1. Blocks the conduction of pain along the nerve fibers.
2. Block the perception of pain by the processes of nerve cells.

Thus, the drug Genferon has pronounced therapeutic effects that can effectively cure long-term chronic inflammatory diseases of the genitourinary tract in men and women.

Indications

Since the range of therapeutic properties of Genferon is quite large, it has found wide application in the complex therapy of various inflammatory diseases of the genitourinary system in men and women. Genferon is used both as an independent drug and as part of complex therapy using non-drug methods.
Genferon is indicated for the following diseases:
  • genital herpes ;
  • chlamydia;
  • mycoplasmosis;
  • candidiasis of the vulva and vagina (for example, chronic recurrent vulvovaginal candidiasis);
  • human papilloma virus (papilloma and condylomas);
  • cervicitis (inflammation of the cervical canal);
  • vulvovaginitis (inflammation of the vagina and vestibule);
  • bartholinitis (inflammation of the Bartholin glands);
  • inflammation of the prostate gland (prostatitis) in men;
  • urethritis (inflammation of the urethra);
  • balanitis (inflammation of the glans penis);
  • balanoposthitis (combined inflammation of the glans penis and foreskin);
  • viral hepatitis.

Contraindications

An absolute contraindication to the use of the drug Genferon is the presence of sensitivity or allergy to any component of the drug. In addition to this absolute contraindication, there are conditions in the presence of which it is necessary to make a balanced decision on taking the drug, and to carry out therapy under close medical supervision. Such relative contraindications include the following conditions:
  • autoimmune diseases (for example, Hashimoto's thyroiditis, systemic lupus erythematosus, type I diabetes mellitus, glomerulonephritis, etc.);
  • exacerbation of allergic conditions;
  • pregnancy up to 12 weeks;
  • children's age up to 7 years.

Instructions for use

Methods of using the drug Genferon differ in men and women.

Scheme of application for women

Depending on the severity of infectious and inflammatory pathologies of the urinary and reproductive systems, the duration of their course, the severity of complaints, women need to use Genferon 250,000 IU, 500,000 IU or 1,000,000 IU. Suppositories are administered twice a day into the vagina or rectum, depending on the location of the pathology (into the vagina for genital tract infections, and into the rectum for inflammation of the urinary tract). Treatment is continued for at least 10 days.

In the presence of a long-term inflammatory disease of the genitourinary tract, after the main course of therapy lasting 10 days, it is necessary to continue taking Genferon for 1-3 months, one suppository every three days.

A severe infectious disease of the genital tract is allowed to be treated with a combination of Genferon suppositories with other suppositories that have antibacterial and antifungal properties. In this situation, 1 suppository of Genferon 500,000 IU is injected into the vagina in the morning, and 1 suppository of Genferon 1,000,000 IU is injected into the rectum in the evening, and the second drug, with pronounced antifungal and antimicrobial activity, is injected into the vagina. Course - 10 days.

In order to sanitize the vagina, normalize microbial biocenosis, treat sexually transmitted infections, and inflammation of the genitourinary system, pregnant women can use Genferon 1 suppository of 250,000 IU twice a day. To do this, one suppository is introduced into the vagina in the morning and evening, for 10 days. Pregnant women can receive treatment between 13 and 40 weeks.

Scheme of application for men

For the treatment of infectious and inflammatory diseases of the urinary system and genital tract, men use Genferon suppositories in dosages of 500,000 IU and 1,000,000 IU, depending on the severity of the pathology, the duration of the disease and the severity of clinical symptoms.

Genferon for men is administered rectally (into the rectum), one suppository twice a day, for 10 days.

Against the background of the use of the drug Genferon, vitamin therapy (B and C) can be used, which significantly increases the effectiveness of the drug.

Scheme of application for children

Children under 7 years of age can use the drug Genferon Light at a dosage of 125,000 IU, only on the recommendation of a pediatrician.

Children and adolescents aged 7–14 years can safely use Genferon suppositories at a dosage of 250,000 IU. Adolescents over 14 years of age can use the drug in any dosage (250,000 IU, 500,000 IU and 1000,000 IU), depending on the severity of the disease.

Genferon is most often used to treat acute respiratory viral diseases or urinary tract infections in children. Candles for children are administered exclusively rectally, that is, into the rectum. Avoid the introduction of Genferon into the vagina in girls under 7 years of age, since the microflora of the child is not sufficiently developed and is not ready for exposure to aggressive chemicals.

So, for the treatment of acute viral infections in children, one suppository is administered into the rectum twice a day, for 5 days. If the disease is protracted or chronic, then the duration of treatment is extended to 10 days. After the end of the course, in order to prevent the recurrence of a viral infection and strengthen the child's immunity, you can take one suppository rectally, in the evening, once every two days, for 1 to 3 months.

Treatment of diseases of the urinary system and genital organs in children is carried out using a 10-day course of rectal administration of the drug Genferon, one suppository twice a day. It is necessary to ensure that the interval between two injections of Genferon does not exceed 12 hours.

The use of the drug in children must be combined with the intake of vitamins A and C, as well as antibiotics and other drugs that can be used to treat viral or infectious-inflammatory pathologies.

Contraindications for the use of Genferon in children are similar to those for adults (autoimmune pathologies, allergic reactions). If an allergy develops, the drug should be stopped immediately.

Overdose

An overdose of this drug has never been detected to date. However, in the situation of introducing a large number of suppositories at the same time, it is necessary to take a break in the reception for 24 hours, and after a day, continue treatment according to the scheme indicated by the doctor.

Side effects

Side effects rarely develop while taking the drug Genferon. Most often, various manifestations of an allergic reaction are observed, for example, a burning sensation in the vagina or rectum, skin rash, itching. As a rule, such allergic side effects disappear on their own, 3 days after the drug is discontinued. In this case, it is necessary to reduce the dosage.


Rarely, while taking the drug Genferon, the following side effects develop:

  • chills (increased body temperature);
  • loss of appetite;
  • joint pain (arthralgia);
  • a decrease in the total number of leukocytes and platelets in the general blood test.
The above side effects most often develop with a daily dose of Genferon more than 10,000,000 IU.

Interaction with other drugs

The combined use of Genferon with antibiotics and antiseptics enhances the effectiveness of the treatment of infectious and inflammatory diseases of the genitourinary tract.

The following drugs increase the analgesic effect of benzocaine:
1. Non-steroidal anti-inflammatory drugs:

  • sulindac;
  • clofezon;
  • tenoxicam;
  • metamizole;
  • phenacetin;
  • ketorolac;
2. Anticholinesterase drugs:
  • physostigmine;
  • galantamine;
  • prozerin;
  • armin;
  • pyrophos;
  • ezerin.
Sulfanilamide preparations, when used in conjunction with Genferon, lose some of their effectiveness against pathogenic microorganisms.

With an increase in body temperature after taking the drug, a single use of paracetamol at a dose of 500-1000 mg is allowed.

special instructions

Genferon does not affect the activity of the nervous system, so a person can do any work associated with increased concentration and concentration (for example, drive a car).

Genferon during pregnancy

The drug Genferon is safe during pregnancy at 13-40 weeks, and for lactating women, at a dosage of 250,000 IU. The decision to use Genferon in pregnant and lactating women should be made taking into account all possible risks and expected benefits.

If there is a need to take Genferon during lactation, then it is better to temporarily transfer the child to artificial mixtures.

The use of the drug Genferon in pregnant women up to 12 weeks is undesirable, since there are no objective data on the effect of the drug on the body of the mother and fetus.

The use of Genefron in children

Genferon in children is used as an antiviral agent for the treatment of acute respiratory infections and inflammation of the urinary system. However, the drug should be used with caution and only if the expected benefit far outweighs all possible risks.

For the treatment of viral infections in children, it is better to use specially designed drugs that take into account the functioning of the child's immune system. It should be remembered that a child is not a miniature adult, his immune system functions in a completely different way, immune mechanisms work in different modes.

Reviews

To date, the immunomodulator Genferon has good recommendations, which are provided by the high efficiency of the drug. This drug is more often used by people who have been suffering from chronic diseases of the urinary and reproductive systems for a long time, and who have undergone numerous courses of treatment. In such situations, the completed course of treatment ensures the remission of the disease, but due to the failure of one's own immune system, the slightest fluctuations can lead to a relapse or the development of dysbiosis, which can exist for years, reducing the quality of life. The introduction of the immunomodulator Genferon into the complex therapy allows avoiding relapses and restoring the normal microflora of the genitourinary system. In the vast majority of cases, therapy is successful, and there are no relapses of the painful disease, so people leave positive feedback about Genferon.

In rare cases, you can find negative reviews about the drug. This may be due to improper use of the drug, lack of indications, or profound disorders of the immune status, which requires serious correction. If a person has serious immunity disorders, then Genferon will not have a significant effect, and relapses of the disease will develop. Very rarely, people do not have sensitivity to interferon produced by a certain type of microorganisms, which also leads to the absence of a positive effect from the drug. In this case, people leave negative feedback.

The use of Genefron in children - reviews

Reviews about the use of the drug in children are very numerous and varied - from enthusiastic to extremely negative. This polarization of opinions is due to the fact that Genferon is not a specialized children's drug that takes into account the functioning of the child's immune system. Therefore, the effectiveness of the drug depends on the many individual characteristics of the child, and the characteristics of the pathological process. This explains why taking Genferon helped some children to recover completely, while others did not have a significant therapeutic effect.

Each parent must decide for himself whether to use Genferon to treat his child, after carefully weighing the expected effect and all possible risks. If in doubt, it is better to replace it with a special children's antiviral drug, which is designed taking into account the age-related characteristics of the child's immune system.

Genferon or Viferon - which is better?

Genferon and Viferon belong to the same group of drugs, and are analogues, that is, they contain the same active substance - interferon alfa 2b. The spectrum of action and effectiveness of these drugs are the same.

However, when deciding the question: "Which is better - Genferon or Viferon?" it is necessary to take into account not only the data of "dry" science, but also the individual characteristics of a person, including psychological ones. The active substance of the preparations Genferon and Viferon is produced by special bacteria, so its activity and affinity for the tissues of a particular human body may vary. In one case, the patient can get an excellent effect from the use of Genferon, and another time the same drug will be completely useless. Then it is better to switch to Viferon.

Also of great importance is the psychological component, which is formed by the opinions of acquaintances, friends, relatives and colleagues. When a person is positive about the drug, then the effectiveness of its action will undoubtedly be higher. If you do not trust the drug, it is better to opt for the remedy that seems to you the best.

Viferon and Genferon show different effectiveness against pathogenic Candida fungi, which is due to a greater or lesser effect on a specific type of microorganism. Viferon more effectively suppresses some varieties of the Candida fungus, and Genferon - others. Therefore, the effectiveness of drugs will be determined by the specific type of this fungus that a person has.

Price

Candles Genferon can be purchased at a pharmacy or through an online store. The manufacturer recommends dispensing the drug by prescription, but Genferon can often be purchased without a doctor's prescription.

The price may be different, and depends on the pharmacy chain's markup, transportation costs, etc. Since Genferon is produced by Biocad CJSC, there is no difference between a cheaper and more expensive drug.

So, the average price for 10 Genferon suppositories 250,000 IU is 310 - 415 rubles. The cost of 10 suppositories of Genferon 500,000 IU is on average 402 - 539 rubles, and the price of 10 pieces of Genferon 1,000,000 IU ranges from 552 to 700 rubles.

Analogues

Today, the range of immunomodulators with antiviral properties is quite wide. Analogues of Genferon include the following drugs that have a similar effect:
  • lyophilisate for the preparation of Avonex solution;
  • solution for intramuscular injection Avonex;
  • solution for injections Altevir;
  • Alfaron lyophilisate (for intranasal administration and for injections);
  • solution for injection Alfaferon;
  • lyophilizate Betaferon (for subcutaneous administration);
  • gel for local use Viferon;
  • ointment for local use Viferon;
  • rectal suppositories Viferon;
  • Genfaxon solution (for subcutaneous injection);
  • suppositories vaginal and rectal Giaferon;
  • ointment for topical application Diaferon;
  • lyophilizate Ingaron (for intramuscular, subcutaneous and intranasal use);
  • lyophilisate Interal-P (for injections);
  • lyophilizate Interferal (for injections);
  • interferon recombinant human dry Rekolin (for injections);
  • injection solution - human leukocyte interferon;
  • solution for topical application - human leukocyte interferon;
  • rectal suppositories - human leukocyte interferon;
  • recombinant ointment - Interferon alfa-2 (for local and external use);
  • Intron A solution (for intravenous and subcutaneous use);
  • gel Infagel (for local use);
  • lyophilisate Inferon (for intramuscular injections);
  • Infibeta lyophilisate (for injection);
  • lyophilisate Laifferon (for intramuscular and ocular use);
  • Laifferon solution (for intramuscular and ocular use);
  • Lyophilizate Leukinferon (for injection);
  • lyophilizate Lokferon (for topical application);
  • Pegasys solution in vials and syringe tubes (for subcutaneous injection);
  • lyophilisate Intron (for subcutaneous administration);
  • Realdiron lyophilisate (for intramuscular and subcutaneous use);
  • lyophilizate Reaferon (for injections and topical application);
  • lyophilisate Reaferon-EC (for injections and topical application);
  • Rebif solution (for subcutaneous use);
  • Ronbetal solution (for subcutaneous use);
  • Roferon-A solution (for subcutaneous use);
  • rectal suppositories Sveferon;
  • lyophilizate Sinnoveks (for intramuscular injections);
  • Eberon Alpha R lyophilisate (for injections);
  • Extavia lyophilisate (for subcutaneous injection).

Treatment of genital warts with geneferon

Before use, you should consult with a specialist.
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