Pyobacteriophage polyvalent hydradenitis. "Pyobacteriophage": instructions. "Pyobacteriophage": reviews. Terms of sale and storage

If a patient has a bacterial infection, an antibiotic is often prescribed, but viruses called phages can also be used to treat pathologies caused by pathogenic bacteria.

With their help, drugs are created with a selective effect on certain microorganisms. They contain bacterial phagolysates, that is, purified microbial cells destroyed by phages. One of these drugs are Pyobacteriophages. They are often included in the treatment of purulent infections, including in children.

Release form and composition

Pyobacteriophages are produced by the Russian company Microgen, which also manufactures other immunobiological preparations.

Currently, the bacteriophage with the prefix "pyo" is represented by two means:

"Pyobacteriophage complex";
"Pyobacteriophage polyvalent Sextaphage".

Both preparations are solutions packaged in sterile glass bottles of 20 ml. "Complex Pyobacteriophage" is sold in 8 such bottles in a pack, and is also additionally available in a larger package (100 ml bottles, which are sold in 1 piece). "Sextafag" is presented in packs of 4 and 10 bottles. The solution itself is clear, yellowish or greenish in color.

The main difference between these two drugs is their composition, in particular, the list of microbes destroyed by bacteriophages, which are the active ingredient in the solution.

Sextaphage, as the name implies, contains 6 types of microorganisms:

staphylococci;
streptococci;
proteas;
pathogenic Escherichia coli;
Pseudomonas aeruginosa;
Klebsiella pneumonia.

They are also present in the "Pyobacteriophage complex", but such a medication additionally contains destroyed enterococci and Klebsiella oxytoca. An auxiliary component of both drugs is 8-hydroxyquinoline sulfate (preservative). The effect of such drugs on the body, indications for their use and even dosages are the same, so the information below will relate to both drugs.

Operating principle

The microbes destroyed by phages that are in the "Pyobacteriophage" contribute to the destruction of exactly those types and strains of bacteria from which they were obtained.

This means that "Sextafag" affects strepto- and staphylococci, two types of Proteus and Klebsiella pneumonia, as well as Escherichia and Pseudomonas aeruginosa. "Complex Pyobacteriophage" is also effective against enterococci and Klebsiella oxytoca.

Indications

The reason to prescribe "Pyobacteriophage" may be:

otitis, bronchitis, tonsillitis, rhinitis, tracheitis, sinusitis and other infections of the respiratory system;
furuncle, felon, abscess and other bacterial infections of the skin, bones and soft tissues;
purulent complications in case of skin injuries (burns, wounds, etc.);
cystitis, urethritis and other bacterial lesions of the urogenital organs;
purulent eye infections;
dysbacteriosis;
intestinal infection;
generalized bacterial infections and so on.

The prophylactic use of solutions is in demand for the external treatment of skin lesions and sutures after operations. In addition, drugs are prescribed to prevent nosocomial infection, if there is such a risk.

At what age are they prescribed?

You can use "Pyobacteriophage" in children at any age. This medication is used even in newborns, for example, with sepsis, pyoderma, conjunctivitis or omphalitis.

However, the drug must be prescribed by a doctor after determining the sensitivity of the pathogen.

Contraindications

Treatment with "Pyobacteriophage" is prohibited if the patient has hypersensitivity to any component of the solution. Any other contraindications for such drugs are not indicated.

Side effects

According to the information from the manufacturer, Pyobacteriophage does not provoke any side effects. However, in rare cases, after taking the solution, a skin rash or diarrhea may occur, and in infants of the first months of life, regurgitation may occur. Such negative symptoms should be reported to the attending physician immediately.

Instructions for use

To obtain the desired effect, it is important to follow some rules for using Pyobacteriophage.

Since the medicine is stored in the refrigerator, before giving it to the baby, you should slightly warm the solution by holding the syringe in your hands or typing the remedy for a while (no more than 1 hour).
Before use, the solution must be shaken and its transparency checked. When cloudy, the medication should be discarded. To prevent other microbes from getting inside the vial, it is best to take the drug with a syringe, and the cork and hands should be wiped with alcohol.
Most often, "Pyobacteriophage" is used orally. The remedy is given to the child three or four times a day 1 hour before feeding. The duration of oral administration is from one week to 20 days - the duration of treatment for a particular patient is determined by the doctor.
If the drug is prescribed to a newborn, then the required dose of the solution is diluted with boiled water 1: 2. In the absence of negative reactions and good tolerance, after a few days the drug can be given already undiluted. If the baby refuses to drink "Pyobacteriophage" in its pure form, it is permissible to add a little mother's milk to the medicine.

In addition to oral administration, the drug is often used in the form of enemas. This method is prescribed for children with enterocolitis, vomiting, regurgitation, sepsis and other problems. Rectal administration of the solution involves a high enema (it is performed through a catheter or using a gas outlet tube). The duration of such treatment is usually 7-10 days.
"Pyobacteriophages" are also used externally, for example, they make lotions for suppuration of an umbilical wound or irrigate burned skin. With damage to the conjunctiva, the agent is dripped into the eyes, with rhinitis and adenoids - into the nose, and with stomatitis and sore throat, rinses and inhalations are prescribed. Surgeons, if necessary, introduce such drugs into cavities, for example, inside a joint or into the pleural cavity.
To determine a single dosage, it is important to know the age of the patient. The recommended dose for both oral and rectal administration is indicated in the table in the instructions for Pyobacteriophages. For example, infants up to 6 months old should be given 5 ml of medicine inside, and 10 ml of solution is used for an enema.
For prophylactic use, age dosages are used, but the medicine is given only once a day. The duration of such a reception should be checked with the doctor for each patient separately.

Overdose and drug interactions

Cases of an overdose of "Pyobacteriophage" have not yet been. If the dose is exceeded, it is recommended to monitor the patient and use standard measures. The drugs are compatible with any other medicines, including antibiotics.

If "Pyobacteriophage" is used externally and the skin is treated with an antiseptic before applying it, then the surface must be washed with saline before use.

Terms of sale and storage

"Pyobacteriophages" are sold without a prescription and are available in most Russian pharmacies. The cost of the drug is affected by the volume of the solution in the vial and the number of vials in the pack. For four bottles of "Sekstafag" or the same package of "Pyobacteriophage complex" you need to pay about 700 rubles.

To store drugs, a low temperature is required (up to +8 degrees), so the medicine should be at home in the refrigerator. The shelf life of both medicines is 2 years. If it has expired, the drug should be discarded, even if the solution is still clear.

Unfortunately, inflammatory diseases of bacterial origin can hardly be considered a rarity. Every person faces similar problems from time to time, regardless of age, gender or other indicators. So what treatments for such ailments does modern medicine offer?

Today, drugs based on bacteriophages are becoming more and more popular. And quite often, doctors prescribe the drug "Pyobacteriophage" to their patients. Instructions for using it are quite simple, but the effect is really there. But what is the peculiarity of this drug? What is included in its composition? Are there any contraindications to therapy? This information will be of interest to many readers.

Description of the composition and form of release of the drug

The preparation "Pyobacteriophage complex liquid" is produced in the form of a clear yellowish solution. The liquid is placed in glass bottles with a capacity of 20 or 100 ml.

This drug is a mixture of bacteriophages, which are obtained by lysis of bacterial cells. In particular, the solution contains bacteriophages that are active against enterococci, staphylococci, streptococci, Klebsiella, Escherichia coli, Pseudomonas and Proteus. The resulting lysate in the production process is carefully filtered from the remnants of pathogenic cells. Quinosol is used as a supporting buffer. By the way, the solution should be stored at a temperature of 2-8 degrees Celsius.

What properties does the drug have?

What effect can provide the drug "Pyobacteriophage"? The instruction says that the medicine copes well with all sorts of infections. But why?

In fact, these drugs have unique properties. Bacteriophages are types of viruses that infect bacterial cells. Penetrating through the cell wall, the virus begins to actively multiply, using cellular resources for this. This, in turn, leads to the death of bacteria, the lysis of their walls and the release of new viral particles.

It should also be noted that the action of bacteriophages is highly specific. Viral particles affect only certain bacterial cells, while not affecting either the structures of the body or the beneficial bacteria that are necessary to maintain the normal functioning of organ systems.

Indications for use

In what cases are patients prescribed the drug "Pyobacteriophage"? The use of this tool is quite wide. It is used to treat inflammatory diseases caused by the activity of phage-sensitive bacteria.

For example, medication is indicated for intestinal infections. In surgical practice, the drug is used to treat suppuration, burns, carbuncles, phlegmon, boils. Also indications for use are infectious tonsillitis, otitis media, pharyngitis, sinusitis, pleurisy, pneumonia, pyelonephritis, cystitis, colpitis, salpingo-oophoritis, etc.

The drug "Pyobacteriophage": instructions for use

Only a doctor can prescribe the use of this drug. The specialist will also determine the most effective dose and duration of therapy. So how to use the tool "Pyobacteriophage"? The instruction in this case depends on the form of the disease, the patient's condition and some other factors.

For example, for skin lesions, the solution is used in the form of wet dressings, applications, irrigations, lotions, etc.
In the treatment of an abscess, a solution with bacteriophages is injected directly into the suppuration cavity, having previously thoroughly cleaned it of the existing purulent masses.
In diseases of the excretory system, the solution can be injected directly into the renal pelvis or into the cavity of the bladder.
Also, the drug can be used for instillation, washing, rinsing (for example, throat), irrigation.
For bowel diseases, enemas based on this solution will be effective.
However, most often the drug is administered orally. In addition, in some diseases it is advisable to combine several methods of administration at once to achieve the maximum result.

The single dose is determined by the doctor. For adult patients and children over eight years old, it is usually 50 ml. You need to take the drug three times a day (the number of doses may decrease if the therapy includes other procedures, such as enemas). The course of treatment in most cases lasts from 5 to 15 days. If we are talking about the prevention of a disease, then a seven-day intake will be enough.

Features of the treatment of children under the age of 6 months

Of course, this drug is widely used in pediatrics for the treatment of newborns and children in the first months of life. Treatment with "Pyobacteriophage" in this case has some features that you should pay attention to.

In the treatment of enterocolitis or sepsis in newborns (including premature babies), the method of so-called high enemas is used. For irrigation of the intestines, special catheters are used. A single dose of enema medication is 10 ml, the procedure is repeated 2-3 times a day. If there is no vomiting, then the child can be given a solution orally, mixing with formula milk or breast milk - a single dose is 5 ml. Quite often, doctors recommend combining the rectal and oral routes of drug administration. The course of therapy, as a rule, lasts from 5 to 15 days.

Are there any contraindications and side effects?

Of course, many people are interested in the question of whether all categories of patients are allowed to take the drug "Pyobacteriophage"? The instruction says that this remedy has no contraindications. Moreover, cases of severe adverse reactions have also not been reported. Sometimes patients have a slight allergic reaction, but this is extremely rare.

The drug "Pyobacteriophage complex liquid" is often used to treat even newborns. Moreover, the drug is indispensable in the treatment of certain infections during pregnancy, because during this period of a woman's life, traditional antibacterial therapy with antibiotics can only do harm.

But, despite all the safety, you should not arbitrarily use the medicine - be sure to consult a doctor before starting therapy.

How much does the medicine cost?

For many patients, the issue of the cost of a particular drug is an important issue. So how much will the drug "Pyobacteriophage" cost? The price, of course, may fluctuate depending on the volume you buy, the manufacturer, and the financial policy of the pharmacy.

On average, a package costs 900 rubles. But keep in mind that to complete the full course of treatment, you will most likely need several of these packages.

What to do if for one reason or another you cannot use "Complex Liquid Pyobacteriophage"? The bacteriophage is also contained in some other preparations - if necessary, you can choose a substitute with almost the same properties. For example, such agents as "Pyobacteriophage polyvalent purified", "Pyopolifag", "Sextaphage" and some others are considered good analogues.

The drug "Pyobacteriophage": reviews of doctors and patients

To date, drugs based on bacteriophages are becoming more and more popular. After all, standard therapy with antibiotics is not suitable for everyone and is often associated with side effects. And in such cases, doctors prescribe the drug "Pyobacteriophage". Reviews of doctors are positive, as the drug perfectly copes with its main task.

Patients also respond well to this remedy. It helps to cope with staphylococcus and other pathogenic microorganisms, does not harm health and has practically no contraindications. As for the negative aspects, here it is worth mentioning the price, which for some patients may be too high. The disadvantages include not too pleasant taste, as well as some difficulties that arise with the storage of the drug. But in any case, health is worth all the inconvenience.

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POLYVALENT PURIFIED PYOBACTERIOPHAGE

Before use, the bacteriophage vial must be shaken and viewed. The drug should be clear and free of sediment.

Attention! Do not use the drug in case of turbidity!

Due to the content in the preparation of a nutrient medium in which bacteria from the environment can develop, causing clouding of the preparation, it is necessary to observe the following rules when opening the vial:

Wash your hands thoroughly;

Treat the cap with an alcohol-containing solution; remove the cap without opening the cork;

Do not put the cork with the inner surface on the table or other objects;

Do not leave the vial open;

Opened vials should only be stored in the refrigerator.

When using small doses (2-8 drops), the drug must be taken with a sterile syringe in a volume of 0.5-1 ml.

The drug from the opened bottle, subject to the storage conditions, the above rules and the absence of turbidity, can be used during the entire shelf life.

The drug is used for oral administration (through the mouth), in the form of enemas, applications, irrigation, injection into the cavity of wounds, vagina, uterus, nose, sinuses, as well as into drained cavities: abscesses, abdominal, pleural, bladder, renal pelvis.

Inside the drug is taken on an empty stomach 0.5-1 hour before a meal.

Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug orally.

If the cavity of the purulent focus is treated with chemical antiseptics, it must be washed with a sterile 0.9% sodium chloride solution before using the bacteriophage.

In the treatment of tonsillitis, pharyngitis, laryngitis, the drug is used for rinsing the mouth and throat 3 times a day, 10-20 ml, the course of treatment is 7-10 days.

In the treatment of bronchitis, pneumonia, the drug is taken orally 3 times a day, 10-20 ml, and also used in the form of aerosols and inhalations (without heating and using ultrasound), the course of treatment is 15-20 days.

In the treatment of otitis media, the drug is used for washing and introducing into the middle ear cavity 2-5 ml 1-3 times a day. The course of treatment is 7-15 days.

In the treatment of inflammation of the sinuses, the drug is used to wash the nasal cavity, nasopharynx and sinuses at a dose of 5-10 ml and inject 2-3 ml into the sinuses. The procedure is repeated once daily for 7-10 days. In addition, the drug is injected into the nasal cavity in the form of turundas moistened with bacteriophage, in turn into each nasal passage and left for 0.5-1 hour. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.

In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of mouth rinses 3-4 times a day at a dose of 10-20 ml, as well as the introduction of bacteriophage-impregnated turundas into periodontal pockets for 5-10 minutes, the course of treatment is 7-10 days.

With conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days; with a purulent corneal ulcer - 4-5 drops per day for 7-10 days, with purulent iridocyclitis - 6-8 drops every 3 hours in combination with ingestion in therapeutic dosages for 7-10 days.

In case of an abscess after opening and removing the purulent contents, the drug is administered in an amount less than the volume of the removed pus once a day, the course of treatment is 7-10 days.

In case of peritonitis and pleurisy, the drug is injected into the drained cavities - abdominal and pleural through the drainage tubes once daily 20-70 ml, the course of treatment is 10-15 days.

In osteomyelitis, the drug is injected into the wound cavity through turundas, drainages in the amount of 10-30 ml once daily, the course of treatment is 15-20 days.

In the treatment of mastitis, suppuration of wounds and burns, the drug is used in the form of irrigation, applications, dressings, injection into the drainage at a dose of 5-50 ml, depending on the lesion at least 1 time per day, the course of treatment is 10-15 days.

In the treatment of purulent-inflammatory gynecological diseases (suppuration of wounds, endometritis, vulvitis, bartholinitis, colpitis, salpingo-oophoritis), the drug is used for irrigation, applications, injected into the cavity of wounds, vagina, uterus, 5-20 ml once a day for 7-10 days.

For cystitis, pyelonephritis, urethritis, the drug is taken orally at a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. In the event that the cavity of the bladder or renal pelvis is drained, the drug is administered through a cystostomy or nephrostomy 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days.

With gastroenterocolitis, pancreatitis, cholecystitis, as well as intestinal dysbacteriosis, the bacteriophage is taken orally in age dosages 3 times a day 1 hour before meals for 7-15 days (according to clinical indications). With indomitable vomiting, the drug is used in the form of high enemas 2-3 times a day, 20-40 ml each. With intestinal dysbacteriosis, the drug can be used with normoflora preparations.

For the prevention of nosocomial surgical infections, the drug is used to treat postoperative and freshly infected wounds at a dose of 5-50 ml, depending on the lesion, once daily for 5-7 days.

The use of the drug in children under 1 year (including premature babies)

With gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used by mouth 2-3 times a day, 3-5 ml 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas outlet tube or catheter) once a day at a dose of 5-10 ml. Perhaps a combination of rectal (in the form of high enemas) and oral administration of the drug. The course of treatment is 7-15 days (according to clinical indications). With a recurrent course of the disease, repeated courses of treatment are possible.

In the treatment of omphalitis, pyoderma, infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or the affected area of the skin) for 7-15 days.

In order to prevent the occurrence of nosocomial infection in newborns, the bacteriophage is used according to epidemic indications orally, 3-5 ml 3 times a day 30 minutes before feeding during the entire stay in the hospital.

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Polyvalent Pyobacteriophage

Compound

The composition of the drug contains the active substance of pyobacteriophage (a mixture of filtrates of sterile phagolysates, streptococci, Proteus, Pseudomonas aeruginosa, staphylococci, enterococci, Klebsiella, Escherichia coli) 10 ml per vial.

Also, the composition of the drug includes excipients - preservatives.

Release form

Solution in a vial of 20 ml, ampoules of 10 and 5 ml. In a carton box 4 bottles, ampoules - 5 or 10 pieces.

pharmachologic effect

Antibacterial, immunostimulating agent.

Pharmacodynamics and pharmacokinetics

The drug specifically lyses Proteus bacteria, streptococci, staphylococci, Klebsiella pneumoniae, Pseudomonas aeruginosa, various serogroups of Escherichia coli. Thus, providing an immunostimulating effect on the body.

Indications for use

Liquid Pyobacteriophage is prescribed:

for the treatment and prevention of purulent, inflammatory, gastrointestinal diseases;
with peritonitis, pleurisy, osteomyelitis, mastitis, purulent wounds and skin lesions;
for the treatment of tonsillitis, stomatitis, otitis, sinusitis, pleurisy and pneumonia;
with pancreatitis, gastroenterocolitis, cholecystitis, dysbacteriosis;
for the treatment of cystitis, endometritis, colpitis, pyelonephritis;
with suppuration of the cornea, conjunctivitis;
with omphalitis, pyoderma, enteritis, various dysbiosis, septicemia, septicopyemia.

Contraindications

Doesn't have.

Side effects

Not registered.

Instructions for Pyobacteriophage Polyvalent purified (Method and dosage)

According to the instructions for use of Pyobacteriophage Polyvalent, enemas, lotions and irrigation are done with the drug. It is also possible to use the drug intracavitary and inside.

Frequency of application 1-3 times a day. The course, as a rule, is from 5 to 15 days.

For the treatment of pyelonephritis, 5-20 ml are administered orally, 3 doses.

How to give to a child?

With the manifestation of indomitable vomiting in children under one year old, you can additionally administer the drug through a probe, 3-5 ml every day. The course is 5-7 days.

For the treatment of omphalitis and pyoderma in newborns, the drug can be used in the form of applications, twice a day. The course of piopolyvalent bacteriophage is from 5 days to a week.

Overdose

No cases of overdose have been reported.

Interaction

In parallel with drug treatment, other anti-inflammatory and antibacterial agents can be used.

Terms of sale

No prescription needed.

Storage conditions

Temperature from 2 to 8 degrees. The shelf life at temperatures up to 25 degrees is reduced to one month. Use immediately after opening. With the appearance of flakes, inhomogeneity of the solution, after the expiration date, Bacteriophage cannot be used.

Best before date

24 months.

Analogues

Analogues: Pyobacteriophage, Pyobacteriophage Complex Liquid, Pyopolyphage, Sextaphage.

Complex Bacteriophage and Polyvalent Pyobacteriophage

The only difference between the Complex Pyobacteriophage and the Polyvalent Pyobacteriophage is that the latter does not contain Enterococcus phagolysate. The drugs have a common manufacturer.

Reviews for Pyobacteriophage Polyvalent Purified

Reviews of doctors are good. It is also used by surgeons for postoperative wound treatment, and pediatricians, and gynecologists with urologists. Some believe that the drug is more effective and safer to use than antibiotics.

The reviews on the forums are very good. Many used the drug and were satisfied with the result. Bacteriophage is especially effective for children, due to the absence of side effects, often newborns are allergic to antibiotics.

Price of Polyvalent Pyobacteriophage, where to buy

The price of Pyobacteriophage Polyvalent purified in Ufa is about 650 rubles.

You can buy a remedy in Moscow for 700 rubles, for 4 ampoules of 20 ml each. Sometimes the agent may be called PIOpolyvalent Bacteriophage.

NOTE! Information about medicines on the site is a general reference, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medicines in the course of treatment. Before medicine use the Polyvalent Pyobacteriophage surely consult with the attending physician.

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Bacteriophage complex: instructions for use, analogues and reviews

Diseases of bacterial etiology are most often treated with antibacterial drugs that have a wide spectrum of action. Bacteriophages are recommended for the selective destruction of disease-causing agents. Such drugs have many advantages over other medicines. A complex bacteriophage is a drug that contains several types of bacteriophages at once. Let us consider in more detail the mechanism of action and the scope of this drug.

What are bacteriophages?

Each ailment needs specific treatment. To choose the right method of therapy, it is important to determine the type of pathogen. To combat bacterial pathologies that are characterized by severe course and consequences, doctors often prescribe bacteriophages. These drugs are useful viruses for the human body that use harmful bacteria to reproduce and continue their life. At the same time, they have a negative impact only on pathogenic microorganisms and do not affect the functioning of organs and systems.

Unlike antibiotics, bacteriophages do not destroy the beneficial microflora and do not cause the development of dysbacteriosis. Preparations can be taken on a long-term basis and not be afraid of the emergence of resistance of pathogenic microorganisms to the active ingredients.

In pediatric practice, a polyvalent bacteriophage is often used. Reviews (for children, the medicine is prescribed after the diagnosis is established), specialists confirm the effectiveness of the drug, provided that the type of pathogen is accurately determined. To do this, before starting therapy, it is necessary to undergo laboratory diagnostics. Bacteriophages are considered as powerful drugs as antibiotics.

Latin name:
Pyobacteriophagum Polyvalentum
ATX code: V03A
Active substance: Pyobacteriophage
Manufacturer: Microgen NPO, Russia
Pharmacy leave condition: Without recipe
Price: from 700 to 800 rubles.

Purified polyvalent pyobacteriophage (Sextaphage) is a medicinal product used in therapeutic and prophylactic treatment of infections accompanied by purulent and inflammatory processes. Belongs to the category of antibacterial and immunostimulating drugs with a wide spectrum of effects. Contains a mixture of bacteriophages.

Indications for use

Sextaphage is used in medical practice in the treatment of pathologies caused by staphylococci, streptococci, Proteus, Escherichia coli and others. Most often prescribed for such ailments:

ENT pathologies and respiratory diseases (pharyngitis, pneumonia, bronchitis, inflammation of the middle ear)
Purulent wounds, burns, various kinds of boils, abscess
Urological infectious diseases
Conjunctivitis, purulent ulcers on the cornea resulting from trauma
Generalized septic pathologies
Diseases caused by intestinal viruses
Purulent pathologies accompanied by inflammation in newborns.

In severe infectious diseases that have arisen against the background of the above bacteria, Pyobacteriophage polyvalent purified is prescribed in combination with other medicines.

In addition to therapy, it is also appropriate to use Sextafag for prophylactic purposes in the treatment of wounds in the postoperative period.

Compound

Purified polyvalent pyobacteriophage includes the following main components: a mixture of phagolysate of staphylococci, streptococci, Escherichia coli, Proteus, Pseudomonas aeruginosis and Klebsiella pneumoniae. Additional ingredient: preservative 8-hydroxyquinoline sulfate monohydrate.

Medicinal properties

Purified polyvalent pyobacteriophage has a detrimental effect on microorganisms such as staphylococci, streptococci, Escherichia coli and some others. It is characterized by anti-inflammatory and antibacterial effects.

The average price is from 700 to 800 rubles.

Release forms

Purified polyvalent pyobacteriphage (Sextaphage) is represented by a light liquid with a yellowish or greenish tint. Produced in glass bottles of 20 ml. One package contains 4 vials. Sextafag is also offered in ampoules of 10 ml and 5 ml.

Mode of application

Assign Pyobacteriophog polyvalent purified for internal use, and also used topically and for intracavitary administration. Locally used as compresses, irrigation, for the treatment of wounds. Intracavitary injection is indicated in the area of the nasal sinuses, bladder, vagina, etc. Also, the medicine is prescribed orally, sometimes administered with a probe, and enemas are made.

Depending on the nature of the disease, the dosage may vary, the recommended doses are:

For children up to six months, a single dose is 5 ml, with rectal administration - 10 ml. For babies up to a year - 10 ml and 20 ml with rectal administration. For children under 3 years of age, the recommended dose is 15 ml orally and 20 ml enema. Children under 8 years of age should be given 20 ml internally and 30-40 ml rectally
A single dose for adults and adolescents is 20-30 ml orally and 40 ml rectally. The duration of the therapeutic course is determined by the specialist
During the treatment of purulent inflammation, the drug is prescribed topically as lotions. With abscesses, it is introduced into the affected cavity, after the removal of suppuration
In case of bronchitis or pneumonia, the medicine should be taken 10-20 ml internally 3 times a day. It is also recommended for inhalation. The duration of therapy is 15-20 days. With angina and pharyngitis, this solution is used for rinsing 10 ml 2-3 times a day, a week
In case of urological infections, Sectafage is injected into the bladder cavity in an amount of 15-20 ml.
For ophthalmic diseases, the medication is prescribed orally, as well as drops 4-5 times a day.
For various intestinal infections, Pyobacteriophage polyvalent purified is taken orally 1-2 hours before meals for one week or administered with an enema.

During pregnancy and breastfeeding

In the treatment of diseases of an infectious nature, women during childbearing and when feeding Pyobacteriophage polyvalent purified can only be used as directed by a doctor.

Contraindications and precautions

The solution has practically no restrictions, the only one of them is the individual intolerance of its components.

It is necessary to open the polyvalent purified Pyobacteriophage (Sextaphage), adhering to all the rules of antiseptics. Before use, the medication should be shaken well, if the liquid is clear, then such a drug is approved for use. It must be remembered that when turbidity, the use of medicine is prohibited!

It is not advisable to leave the opened bottle open, it must be stored in a cool place. When it is necessary to use a small dosage, it is best to use a sterile syringe, which draws the solution from the container.

Cross-drug interactions

Sextaphage is approved for use with other antibacterial and anti-inflammatory drugs.

Side effects

To date, adverse reactions are unknown.

Terms and conditions of storage

The medicine must be stored in a dry and dark place, at a temperature of 2-8 degrees Celsius. The shelf life is 2 years.

Analogues

Pybacteriophage complex liquid

Microgen NPO, Russia
Price from 800 to 900 rubles.

Pyobacteriophage complex liquid is prescribed for the treatment of infections accompanied by purulent and inflammatory processes. It has antibacterial action against many microorganisms. The difference between the complex Pyobacteriophage and the polyvalent Pyobacteriophage is that the composition of the polyvalent Pyobacteriophage does not include enterococcus phagolysate. Pyobacteriophage complex liquid is offered as a solution.

pros

Virtually no side effects
Allowed in pediatrics

Minuses

Not very pleasant taste
Fairly high cost.

Microgen NPO, Russia
Price from 700 to 800 rubles.

Staphylococcal bacteriophage is often contained in the Pyobacteriophage combined or produced independently. Staphylococcal Sextaphage contains bacteriophages that can only deal with staphylococci. Used for diseases caused by these microorganisms.

pros

Can be used for both indoor and outdoor use
Does not adversely affect other organs, unlike antibiotics

Minuses

Narrow spectrum of action
It is advisable not to use for a long period.

Microgen NPO, Russia
Price from 700 to 750 rubles.

Streptococcal bacteriophage is a drug that is effective against streptococci. It is used in pulmonology, otolaryngology, in the treatment of urological, enteral and some other infections.

pros

Does not change the intestinal microflora
Can be given to children

Minuses

Difficulty - not available in all pharmacies.

Many patients are categorically disposed towards antibiotics, however, there are such clinical pictures in which it is simply impossible to do without representatives of this pharmacological group. A common medical preparation is Pyobacteriophage polyvalent, which is produced in the form of a therapeutic solution, is taken orally, externally and topically.

General description of the drug

After processing cultures of bacteria such as E. coli, streptococcus, staphylococcus, proteus, enterococcus and others, a medical preparation called Pyobacteriophage polyvalent was developed. In fact, this is a mixture of bacteriophages necessary for the productive suppression of the activity of pathogenic flora. The drug is represented by a therapeutic solution of yellow, transparent or greenish color.

Since this medical preparation is a mixture of bacteriophages in its chemical composition, in practice it has a wide spectrum of action, i.e. active against a number of colonies of harmful microorganisms. This is the safest method of treatment, since the active components of the drug do not interact with the cells of the body, beneficial bacteria.

According to its pharmacological properties, it is an immunostimulating and antibacterial agent that demonstrates a gentle, but targeted effect directly on the foci of pathology. Pyobacteriophage polyvalent has no complete analogues in modern pharmacology, the list of contraindications and side effects is minimal. You can buy it at a pharmacy, it is dispensed without a prescription.

Indications for use

The appointment of this medication is appropriate for inflammatory, purulent, infectious processes, when the cause of the pathology is the increased activity of streptococci, staphylococci, enterococci, Escherichia coli, Proteus. More often, doctors recommend such an antibacterial drug in the following clinical pictures:

surgical infections (peritonitis, suppuration of open wounds, pleurisy, mastitis);
extensive lesions of the digestive tract (dysbacteriosis, pancreatitis, cholecystitis);
urogenital infections (colpitis, vulvitis, cystitis);
purulent-inflammatory pathologies of ENT practice (frontal sinusitis, tonsillitis, sinusitis);
prevention of intrauterine infections;
diseases of ophthalmology of an infectious nature (keratoconjunctivitis, conjunctivitis, purulent corneal ulcer).

The use of this medication should not be unauthorized, only the attending physician can determine the daily doses, the method of using the antibiotic, and the duration of intensive care. Superficial self-treatment can only aggravate the clinical picture, provoke complications.

Contraindications for use

Despite the fact that Pyobacteriophage polyvalent belongs to the group of antibiotics, its use is allowed for all categories of patients, from newborns to deep pensioners. There are no medical contraindications in full, moreover, the increased sensitivity of the body to active components is completely excluded. Pregnant women, young mothers during breastfeeding are no exception. Such categories of patients can also receive such an appointment from the attending physician.

Side effects and cases of overdose

During intensive care, the occurrence of side effects is excluded, and cases of overdose have not been recorded at all in extensive medical practice. Pyobacteriophage polyvalent is an absolutely safe medical preparation, moreover, it can be safely combined in one treatment regimen with other antibiotic agents.

Method of application and daily doses

The indicated medication is distinguished by several ways in which the drug enters the weakened body. These are applications, compresses, mucosal irrigation, oral administration, enemas, drainage of internal cavities. Which method of application is suitable in a particular clinical picture is determined by the attending physician. In addition, prescribes daily doses, specifies the time frame for the course of antibiotic therapy. So:

Treatment of tonsillitis, sinusitis, frontal sinusitis, pharyngitis, laryngitis proceeds with mandatory rinsing of the pharyngeal mucosa. Antibiotic use in the amount of 10-20 ml three times a day for a week.
In the complex therapy of bronchitis, Pyobacteriophage polyvalent is used as inhalations, aerosols. The main method of application is inside 10 ml three times a day. Treat 10 days.
If otitis media progresses, it is required to instill the auricle up to 3 times a day, with a single dose of 2-5 ml. The course of intensive therapy - until the alarming symptoms disappear completely.
When sinusitis or another infectious disease of the nasal passages develops, this medication can be safely used as nasal drops. For 10 days, drop 3 drops into each nasal passage.
If periodontitis of a chronic form unexpectedly reminded of itself, rinsing the mouth with the polyvalent Pyobacteriophage medicine will help to suppress an acute attack of pain. Carry out procedures for 10 days.
When the disease develops in the field of ophthalmology, inflamed eyes are dripped with an antibiotic for 10 days. Single doses are negotiated individually, detailed in the instructions for use.
In case of damage to the genitourinary system, the drug is taken orally for 10 days. Drink a single dose of 20-50 ml an hour before a meal, while depending on the clinical picture, the doctor makes individual adjustments.
If the digestive tract becomes the focus of the pathology, the polyvalent Pyobacteriophage is also taken orally, but already for 2-3 weeks. A single dose of the drug is 20-40 ml, it is indicated to use one hour before the main meal.
For open wounds, suppuration, cuts and other soft tissue injuries, in order to avoid further infection, the doctor prescribes Pyobacteriophage polyvalent externally. Most often, these are applications that are supposed to be performed for 7 days.
If the medicine is used for prophylactic purposes, daily doses and other details of such measures must be determined individually by a doctor, depending on the specifics of the organic resource.

It is important to know not only the dose, but also the way the drug is used. For example, before opening the bottle, you need to shake it well, and then observe the color of the medicine. If a cloudy precipitate appears, or the liquid is not clear enough, it is better to check the expiration date of the antibiotic, temporarily stop taking it. If the medicine is suitable for use, the rules for its use are as follows:

Wash hands before using Pyobacteriophage polyvalent liquid.
The rubber stopper of the vial with repeated use is recommended to be treated with alcohol, to exclude the unsuitability of the indicated antibiotic.
If the drug is used repeatedly, it is supposed to store it only in the refrigerator.
When using relatively small doses of the drug, draw up a portion exclusively with a sterile syringe.
Do not leave the vial open.

Subject to the above rules, you can use the opened bottle of Pyobacteriophage polyvalent throughout the entire shelf life.

special instructions

Since this is an antibiotic, it is important to coordinate its appointment with the local therapist (pediatrician), another narrowly specialized specialist. The drug Pyobacteriophage polyvalent can be an independent therapeutic agent, or be part of complex therapy with representatives of other pharmacological groups. There is no drug interaction.

The drug is dispensed without a prescription, moreover, it is approved for use by premature babies in conditions of mandatory hospitalization. A child can learn about this antibiotic in the prenatal period, when there is a need for urgent treatment of a pregnant woman.

Data on the compatibility of Pyobacteriophage polyvalent and alcohol are completely absent. It is also known that this combined antibiotic does not reduce the patient's concentration, does not affect the quality of driving during the period of antibacterial therapy.

The drug has several varieties of the same remedy. In this case, we are talking about Pyobacteriophage polyvalent, purified, staphylococcal and Sextaphage. The specific name depends on the characteristics of the clinical picture, the intended method of using the antibiotic agent.

It remains only to add that the reviews of such treatment are positive. Doctors prescribe Pyobacteriophage polyvalent in inflammatory and infectious processes, while not fearing for the health of a weakened body. So at the first symptoms from the list of indications, you should definitely pay attention to this natural antibiotic.

Rate Pyobacteriophage polyvalent: instruction!

Description of the composition and form of release of the drug

The preparation "Pyobacteriophage complex liquid" is produced in the form of a clear yellowish solution. The liquid is placed in glass bottles with a capacity of 20 or 100 ml.

What properties does the drug have?

What effect can provide the drug "Pyobacteriophage"? The instruction says that the medicine copes well with all sorts of infections. But why?

Indications for use

In what cases are patients prescribed the drug "Pyobacteriophage"? The use of this tool is quite wide. It is used to treat inflammatory diseases caused by the activity of phage-sensitive bacteria.

The drug "Pyobacteriophage": instructions for use

For example, for skin lesions, the solution is used in the form of wet dressings, applications, irrigations, lotions, etc.
In the treatment of an abscess, a solution with bacteriophages is injected directly into the suppuration cavity, having previously thoroughly cleaned it of the existing purulent masses.
In diseases of the excretory system, the solution can be injected directly into the renal pelvis or into the cavity of the bladder.
Also, the drug can be used for instillation, washing, rinsing (for example, throat), irrigation.
For bowel diseases, enemas based on this solution will be effective.
However, most often the drug is administered orally. In addition, in some diseases it is advisable to combine several methods of administration at once to achieve the maximum result.

Features of the treatment of children under the age of 6 months

Are there any contraindications and side effects?

But, despite all the safety, you should not arbitrarily use the medicine - be sure to consult a doctor before starting therapy.

How much does the medicine cost?

On average, a package costs 900 rubles. But keep in mind that to complete the full course of treatment, you will most likely need several of these packages.

What to do if for one reason or another you cannot use "Complex Liquid Pyobacteriophage"? Bacteriophage is also contained in some other preparations - if necessary, you can choose a substitute with almost the same properties. For example, such agents as "Pyobacteriophage polyvalent purified", "Pyopolifag", "Sextaphage" and some others are considered good analogues.