Almagel neo and difficulty swallowing. Varieties of almagel and the main differences between medicines. Belonging to ATX-classification

Coming to the pharmacy for Almagel, patients will definitely face the question of the pharmacist: which one is needed? The medical staff will briefly list the main differences between the drugs, but an uninformed person may experience a stupor from surprise.

So that the question of the pharmacist is not taken by surprise, we will tell you what varieties of Almagel exist, how they differ, what is their price and in which case each remedy will be most useful.

All forms of Almagel are effective for stomach problems

Tablets and syrups belong to the group of antacids. The basis of all types of liquid form is a suspension of aluminum and magnesium hydroxides. The composition of the tablet preparation includes magaldrate.

The action of any kind is aimed at the symptoms of dyspepsia:

• sour belching;
• heartburn;
• pain in the epigastrium;
• excessive gas formation;
• bloating.

Additionally, drugs act on the condition of the mucous membrane of the esophagus and stomach:

• cover the walls with a protective film;
• reduce the enzymatic activity of gastric juice;
• neutralize excess acid in the stomach;
• reduce the inflammatory response;
• accelerate the healing of erosive and ulcerative lesions;
• minimize the risk of developing gastropathy after taking aggressive medications, such as analgesics, as well as hormones and foods.

All forms are used to treat pathologies of the digestive system, accompanied by normal or:

• acute and chronic gastritis;
• pancreatitis;
• erosion and ulcers;
• dyspeptic symptoms caused by a violation of the rules of a healthy diet or medication;
• hiatal hernia;
• (colitis, enterocolitis);
• gastroduodenitis.

The suspension protects the gastric mucosa from the aggressive internal environment - hydrochloric acid and enzymes

It is also possible to use syrup and tablets for prophylactic purposes in conjunction with drugs that irritate the mucous membranes.

General contraindications for all varieties are:

• hypophosphatemia;
• individual hypersensitivity to components;
• kidney disease, accompanied by severe violations of their functions;
• hypermagnesemia.

Depending on the changes in the composition, the drugs have additional restrictions on the use.

Types of Almagel

There are 3 types of suspensions:

1. No additives (in green packaging).
2. With a carminative component (in an orange box with the additional word Neo).
3. With anesthetic (in a yellow box with the addition of the letter A at the end of the name).

It is additionally produced in tablets, in this case the letter T is attached to the name.

Drug differences

The differences between the varieties are shown in the table:

Tablets differ in composition. Instead of algeldrate, they contain a complex of calcium, magnesium and aluminum salts. In terms of its pharmacological properties, it is not much different from a suspension in a green box. Presented in packs of 12 and 24 tablets.

The maximum duration of therapy with tablets is 2 weeks. The medicine is allowed to be taken on an empty stomach or before meals.

What tool to choose?

The choice of the drug is carried out taking into account the symptoms.

With gastritis

In the initial stage of inflammation, when there is a sharp pain in the epigastrium, a suspension with an anesthetic can be taken as an anesthetic. As the condition improves, it is replaced with the classical form taken by the therapeutic course.

If gastritis is accompanied by excessive gas formation and bloating, it is useful to replace simple Almagel with Neo syrup. It contains a carminative component and reduces the formation of gases.

For pain in the stomach

The most effective remedy is with benzocaine. The anesthetic contained in the syrup in a yellow package will quickly reduce pain.

Despite the absence of an anesthetic additive, the green composition will also cope with soreness in the stomach area.

Stomach pain is a dangerous sign that indicates problems.

For kids

According to the instructions for the preparations, they can be used in children's practice from the age of 10. For children who have not reached it, it is better to choose a safe alternative.

If the child is worried about dyspepsia (discomfort, pain, heartburn) or the doctor has diagnosed a disease of the digestive tract, which is mentioned in the instructions for use, then you can give a suspension in a green pack.

If the pain is unbearable, an anesthetic syrup will help. In this case, the use of the drug should be short-term, because it is a means of emergency care.

Attention! Pain does not need to be endured - it can signal serious surgical pathologies, so you cannot do without calling an ambulance or consulting a doctor.

With the accumulation of gases in the intestinal lumen, which accompanies gastric problems, the use of a suspension in an orange pack is optimal.

During pregnancy

According to the instructions for use, green Almagel can be taken during pregnancy and only in the 2nd and 3rd trimester.

From the beginning of the 2nd trimester of pregnancy, tablets can be used.

The remaining funds from the line are contraindicated for expectant mothers.

Note! Pregnant women should not drink drugs for a long time!

Price table for different types of drug

Almagel's analogs are presented

Which variety has the greatest analgesic effect

Almagel is an antacid agent, the main active ingredient of which is a combination of aluminum and magnesium hydroxides, which neutralizes hydrochloric acid in the stomach. In addition to the usual medicine, Almagel A and Neo are also produced, additionally containing other active ingredients: benzocaine and simethicone, respectively.

Almagel A has the greatest analgesic effect, since it contains a local anesthetic. It is the drug of choice for diseases of the digestive tract, accompanied by severe pain against the background of high acidity. The drug reduces the concentration of hydrochloric acid in the stomach, as well as the activity of the pepsin enzyme, has a protective, adsorbing and enveloping effect. The analgesic effect occurs within two minutes after administration, which allows you to quickly improve the patient's condition with severe pain.

The mechanism of action of the anesthetic benzocaine is to block the work of potassium-sodium channels. This prevents the generation and conduction of nerve impulses: the nerve endings stimulated by pain become unable to transmit a signal to the central nervous system from the area of ​​action of the drug.

Indications for prescribing a variety of the drug with benzocaine are: acute gastritis, duodenitis, pancreatitis, enteritis, peptic ulcer, colitis, hernia of the esophagus, reflux esophagitis.

Almagel Neo is an antacid, adsorbent, carminative and enveloping drug.

Release form and composition

The drug is available in the form of a suspension for oral administration, which is a white or almost white homogeneous liquid with an orange smell (170 ml or 200 ml in dark glass or polyethylene terephthalate bottles with a screw-on plastic cap, in a cardboard box one bottle, a 5 ml measuring spoon and medical instructions for the preparation; 10 ml in multilayer foil sachets, in a carton pack of 10 or 20 sachets and instructions for using Almagel Neo).

Composition per 5/10 ml suspension (one measuring spoon / one sachet):

• active ingredients: magnesium hydroxide (in the form of magnesium hydroxide paste) - 395/790 mg, algeldrate (in the form of aluminum hydroxide gel) - 340/680 mg, simethicone (in the form of an emulsion of simethicone) - 36/72 mg;
• auxiliary components: sorbitol, citric acid monohydrate, propyl parahydroxybenzoate, hydrogen peroxide solution 30%, macrogol 4000, ethanol 96%, sodium saccharinate, propylene glycol, ethyl parahydroxybenzoate, hyethylose, orange flavor, purified water.

Pharmacological properties

Pharmacodynamics

Almagel Neo is a combined drug with enveloping, antacid, carminative and adsorbing effects.

Magnesium hydroxide and aluminum hydroxide (algeldrate) bind bile acids, neutralize free hydrochloric acid and reduce the acidity of gastric juice. Due to the laxative properties of magnesium hydroxide, the slowdown in intestinal motility caused by algeldrate is balanced.

Simethicone prevents the formation of gas bubbles and promotes the destruction of released gas bubbles. The gases that are formed during this are absorbed in the walls of the intestine and, due to peristalsis, are excreted from the body.

Pharmacokinetics

Absorption of magnesium and aluminum ions in the intestine is negligible. In patients with normal renal function, the plasma concentration of magnesium and aluminum does not change. In chronic renal failure, it is possible to increase the level of magnesium and aluminum in the blood to toxic concentrations, since the excretion of these ions is impaired.

Simethicone is chemically and physiologically inert, so it is not absorbed into tissues and organs, and after passing through the digestive tract, it is excreted in its original form.

Indications for use

• exacerbation of peptic ulcer of the duodenum and stomach;
• inflammation of the duodenum in the acute phase;
• duodenogastric reflux (reflux of the contents of the duodenum into the stomach);
• exacerbation of chronic gastritis with normal or increased intestinal secretion;
• acute gastritis;
• reflux esophagitis and gastroesophageal reflux;
• heartburn and gastralgia (due to excessive consumption of coffee, ethanol or nicotine, as well as taking various drugs; due to an incorrect diet that negatively affects the functioning of the organs of the gastrointestinal tract);
• symptomatic ulcers of the gastrointestinal tract of various etiologies;
• exacerbation of chronic pancreatitis or acute pancreatitis;
• erosion of the mucous membranes of the upper gastrointestinal tract;
• flatulence (excessive accumulation of gases in the intestines);
• putrefactive or fermentative dyspepsia.

Contraindications

Absolute:

• low levels of phosphate in the blood (hypophosphatemia);
• chronic renal failure;
• hereditary fructose intolerance;
• senile dementia of the Alzheimer's type (Alzheimer's disease);
• period of pregnancy;
• children under 10 years of age;
• increased individual sensitivity to the main or auxiliary components of the suspension.

Relative (Almagel Neo is used with caution):

• liver disease;
• traumatic brain injury;
• epilepsy;
• brain diseases;
• excessive alcohol consumption;
• breastfeeding period;
• the age of the patient is from 10 to 18 years.

Almagel Neo: instructions for use (dosage and method)

Suspension Almagel Neo is taken orally, not diluted with water and, if possible, not washed down. Within 30 minutes after taking the drug, it is not recommended to drink liquid. Before use, shake the bottle or crush the sachet to homogenize the suspension.

For adults, Almagel Neo is prescribed 10 ml (1 sachet or 2 scoops) four times a day. The drug should be taken one hour after meals and in the evening (before going to bed). If necessary, it is possible to increase the single dose up to 15 ml. The maximum dose of the suspension is 60 ml (12 scoops) per day.

For children and adolescents over the age of 10, Almagel Neo is prescribed by the attending physician. Usually the daily dose of the drug for children is ½ of the daily dose for adults.

Duration of therapy - no more than 4 weeks.

Side effects

During treatment with Almagel Neo, the patient may experience nausea, changes in taste, vomiting, diarrhea or constipation, as well as allergic reactions.

In the case of long-term use of the drug in high doses, the following side effects are observed: hypermagnesemia, hypocalcemia, hyperaluminemia, hypophosphatemia, hypercalciuria, osteoporosis, nephrocalcinosis, osteomalacia, impaired renal function, encephalopathy.

In patients with renal insufficiency, thirst, a decrease in blood pressure and a decrease in reflexes (hyporeflexia) may occur.

Overdose

With prolonged therapy with high doses of Almagel Neo, hypermagnesemia may occur, which is characterized by facial redness, muscle weakness, fatigue, exhaustion and inappropriate behavior.

Symptoms of metabolic alkalosis may appear: slow breathing, muscle pain or numbness, unpleasant taste sensations in the mouth, mental impairment, nervousness, mood changes, fatigue.

In case of an overdose of Almagel Neo, urgent measures must be taken to remove its residues from the body (stimulation of the gag reflex, gastric lavage, oral administration of activated charcoal).

special instructions

Suspension Almagel Neo should be taken separately from other medicines (with an interval of at least 1-2 hours).

If treatment with the drug is prolonged, it is necessary to provide additional intake of phosphates with food.

One scoop (5 ml) of the suspension contains 0.113 g of ethanol, and one sachet (10 ml) contains 0.226 g. The amount of ethanol in the usual daily dose of Almagel Neo (4 sachets or 8 scoops) is 0.904 g, in the maximum daily dose (6 sachets or 12 scoops) - 1.356 g. Due to the content of ethyl alcohol in the preparation, it should be used with caution in patients with epilepsy and alcoholism, patients with diseases of the brain and liver, children and adolescents under 18 years of age.

In one measuring spoon (5 ml) of the suspension, the content of sorbitol is 0.475 g, and in one sachet (10 ml) - 0.95 g. Sorbitol should not be taken by patients with congenital fructose intolerance; it can cause diarrhea and stomach irritation.

Influence on the ability to drive vehicles and complex mechanisms

Almagel Neo does not have any negative effect on the patient's ability to engage in work associated with increased concentration of attention and requiring a quick response (driving vehicles, dispatching and operator activities, etc.).

Use during pregnancy and lactation

Almagel Neo is contraindicated in pregnant women.

During lactation, the drug can only be used as prescribed by a doctor, since controlled clinical trials of the drug for its use during this period have not been conducted.

Application in childhood

In children under 10 years old, Almagel Neo is not used.

In children and adolescents from 10 to 18 years of age, drug treatment is carried out with caution.

For impaired renal function

The drug should not be used in chronic renal failure.

Almagel Neo is prescribed to patients with impaired renal function with caution.

For impaired liver function

Almagel Neo is prescribed to patients with impaired hepatic function with caution.

Use in the elderly

Elderly patients Almagel Neo is prescribed only under the supervision of a physician.

drug interaction

Almagel Neo slows down and reduces the absorption of many drugs: salicylates, H2-histamine receptor blockers, quinolones, tetracycline antibiotics, indirect anticoagulants, beta-blockers, barbiturates, digoxin, chlorpromazine, diflunisal, isoniazid, azithromycin, pivampicillin, fexofenadine, zalcitabine, penicillamine, indomethacin, phenytoin, itraconazole, ketoconazole, cefpodoxime, rifampicin, dipyridamole, lansoprazole, efsodeoxycholic and chenodeoxycholic acids.

With simultaneous use with m-anticholinergics that slow down gastric emptying, the therapeutic effect of Almagel Neo is enhanced and lengthened.

Analogues

Analogues of Almagel Neo are Almagel, Almagel A, Rennie, Vikair, Simalgel-VM, etc.

Terms and conditions of storage

Store in a dark place at a temperature not exceeding 25 °C. The suspension must not be frozen. Keep away from children.

Shelf life - 2 years.

INSTRUCTIONS
on the use of a medicinal product for medical use

Registration number:

Trade name of the drug: Almagel ® Neo

International non-proprietary name:

Dosage form:

Compound
5 ml (one scoop) suspension contains:

Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 340mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 395 mg;
Simethicone (simeticone emulsion - in terms of dimethicone) 36 mg;
The content of excipients in 5 ml of suspension: hydrogen peroxide solution 30% 0.495 mg, sorbitol 474.60 mg, sodium saccharinate 1.13 mg, hyetellose 5.65 mg, citric acid monohydrate 5.65 mg, ethyl parahydroxybenzoate 7.90 mg, propyl parahydroxybenzoate 3.40 mg, propylene glycol 113.00 mg, macrogol 4000 452.00 mg, orange flavor 2.26 mg, ethanol 96% 113.00 mg, purified water up to 5 ml.

10 ml (1 sachet) suspension contains:

Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 680 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 790 mg;
Simethicone (simeticone emulsion - in terms of dimethicone) 72 mg;
The content of excipients in 10 ml of suspension: hydrogen peroxide solution 30% 0.990 mg, sorbitol 949.20 mg, sodium saccharinate 2.26 mg, hyetellose 11.30 mg, citric acid monohydrate 1130 mg, ethyl parahydroxybenzoate 15.80 mg, propyl parahydroxybenzoate 6.80 mg, propylene glycol 226.00 mg , macrogol 4000 904.00 mg, orange flavor 4.52 mg, ethanol 96% 226.00 mg, purified water up to 10 ml.

Description
White or almost white suspension, with an orange odour.

Pharmacotherapeutic group
Antacid + carminative ATX code: A02AF02

Pharmacological properties
Pharmacodynamics
Combined remedy, the action of which is due to its constituent components. It has an antacid, adsorbing, enveloping, carminative effect. Algeldrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, lower the acidity of gastric juice, and bind bile acids. The laxative effect of magnesium hydroxide balances the ability of algeldrate to slow down intestinal motility. Simethicone hinders the formation of gas bubbles and contributes to their destruction. The gases released during this are absorbed by the intestinal walls and excreted from the body due to peristalsis. Pharmacokinetics Due to physiological and chemical inertness, simethicone is not absorbed into organs and tissues and, after passing through the gastrointestinal tract (GIT), is excreted unchanged. Absorption of aluminum and magnesium ions in the intestine is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the level of aluminum and magnesium in the blood may increase to toxic values ​​as a result of a violation of their excretion.

Indications for use
Acute gastritis; chronic gastritis with increased and normal secretory function of the stomach (in the acute phase); acute duodenitis, duodenogastric reflux; peptic ulcer of the stomach and duodenum (in the acute phase); symptomatic ulcers of the gastrointestinal tract of various origins; erosion of the mucous membrane of the upper gastrointestinal tract; gastroesophageal reflux, reflux esophagitis; acute pancreatitis, exacerbation of chronic pancreatitis; gastralgia, heartburn (after excessive consumption of ethanol, nicotine, coffee, taking medications; incorrect diet that adversely affects the functioning of the gastrointestinal tract); flatulence; fermentative or putrefactive dyspepsia.

Contraindications
Hypersensitivity, chronic renal failure, pregnancy, Alzheimer's disease, hypophosphatemia, children under 10 years of age, congenital fructose intolerance. With caution - lactation, liver disease, alcoholism, traumatic brain injury, brain disease, epilepsy, children and adolescents from 10 to 18 years of age.

Dosage and administration

adults
Inside, 2 scoops or 1 packet of suspension with orange flavor 4 times a day 1 hour after meals and in the evening before bedtime. If necessary, a single dose can be increased to 4 scoops or 1 sachet 4 times a day, but the maximum daily dose should not exceed 12 scoops (b packets).

Children over 10 years old
The dosage is determined by the attending physician - usually 1/2 dose for adults. The course of treatment - no more than 4 weeks. Before taking the suspension must be mixed by shaking the vial or carefully kneading the sachet. It is advisable to take Almagel ® Neo without diluting with water and without drinking. It is not recommended to take liquid within half an hour after taking the drug.

Side effect
Allergic reactions, nausea, vomiting, changes in taste, constipation, diarrhea. With prolonged use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis, impaired renal function. In patients with concomitant renal failure - thirst, lowering blood pressure, hyporeflexia.

Overdose
Symptoms. Prolonged use of high doses can lead to the development of hypermagnesemia, which is characterized by rapid fatigue, facial flushing, emaciation, muscle weakness and inappropriate behavior.
There may also be signs of metabolic alkalosis: mood changes, mental impairment, numbness or muscle pain, nervousness and fatigue, slow breathing, unpleasant taste sensations. urgent measures. It is necessary to immediately take measures to quickly remove the drug - gastric lavage, stimulation of vomiting, intake of activated charcoal.

Interaction with other drugs
Almagel ® Neo reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamine receptor blockers, beta-blockers, diflunisal, ketoconazole and itraconazole, isoniazid, tetracycline antibiotics and quinolones, azithromycin, cefpodoxime, pivampicillin, non-direct rifampicillin, anticoagulants, barbiturates, fexofenadine, dipyridamole, zalcitabine, chenodeoxycholic and ursodeoxycholic acids, penicillamine and lansoprazole. M-anticholinergics, slowing down the emptying of the stomach, enhance and lengthen the effect of the drug.

special instructions
The interval between taking Almagel ® Neo and other medicines should be 1-2 hours. With long-term use, sufficient intake of phosphorus from food should be ensured. Due to the lack of data from controlled clinical trials, breastfeeding women should take Almagel ® Neo only after consulting a doctor. One scoop (5 ml) of the drug contains 0.113 g of ethyl alcohol. One sachet (10 ml) of the drug contains 0.226 g of ethyl alcohol. As a result, complications may occur in patients with liver and brain diseases, in those suffering from alcoholism and epilepsy, in pregnant women and children under 18 years of age. The daily dose of the drug (8 scoops or 4 sachets) contains 0.904 g of ethyl alcohol, the maximum daily dose of the suspension (12 scoops or 6 sachets) contains 1.356 g of ethyl alcohol. One scoop (5 ml) of Almagel ® Neo contains 0.475 g of sorbitol. One sachet (10 ml) of suspension contains 0.950 g of sorbitol. Sorbitol is contraindicated in congenital fructose intolerance and may cause stomach irritation and diarrhea. Almagel ® Neo does not adversely affect the ability to drive vehicles and work with mechanisms that require increased concentration of attention and speed of psychomotor reactions.

Release form
Suspension for oral administration.
170 ml or 200 ml of the drug in a glass bottle. Each bottle, along with instructions for use and a 5 ml measuring spoon in a cardboard box.
170 ml or 200 ml of the drug in a bottle of polyethylene terephthalate. Each bottle, along with instructions for use and a 5 ml measuring spoon in a cardboard box.
10 ml of the drug in a bag of multilayer foil. 10 or 20 sachets with instructions for use in a cardboard box,

Storage conditions
In a place protected from light at a temperature not exceeding 25 ° C. Do not freeze! Keep out of the reach of children!

Best before date
2 years.
Do not use after the expiry date stated on the packaging.

Terms of dispensing from pharmacies
Without recipe.

Manufacturer
Balkanpharma-Troyan AD, Bulgaria,
5600 Troyan, st. "Krayrichna" № 1

Consumer claims should be sent to:
LLC ACTAVIS
127018, Moscow, st. Suschevsky Val, 18

Today, people are increasingly suffering from diseases of the gastrointestinal tract, among which gastritis and ulcers are the most common diagnoses. To combat such ailments, there are many drugs that have proven their effectiveness more than once. Almagel is considered one of these drugs. It has been known for over 40 years and has been successfully used to this day to treat diseases of the digestive system. Today we will find out how the types of Almagel differ from each other, and how this medicine acts on the body.

Almagel copes well with diseases of the gastrointestinal tract, regulating the level of hydrochloric acid in gastric juice. The drug has proven itself on the good side, as it does not cause a shift in the pH balance of the stomach and intestines, does not affect the state of the blood and the excretory system.

Types of Almagel

This is an antacid drug that neutralizes the acidity of gastric juice and suppresses its excessive proteolytic activity. There are several types of Almagel, and how they differ from each other needs to be sorted out. Let's start with external differences:

• Almagel - in green packaging;
• Almagel A - in yellow packaging;
• Almagel Neo - in orange packaging.

All preparations are produced in the form of a thick white suspension in a 170 ml plastic bottle, sold in a cardboard box. Instructions for use are attached. Only Almagel Neo goes on sale in the form of sachets of 10 ml, packed in a box of 10 or 20 pcs. Almagel is also in the form of tablets, as a replacement for the suspension. Sold in packs of 12 and 24.

It is worth noting that the drug has two spellings of the name: Almagel and Almagel. However, these are the names of the same medication.

Composition and action

The composition of the drug includes the active substance and auxiliary components. It is the active ingredients that determine the therapeutic effect of all forms of Almagel.

Almagel

Qualitative composition of the suspension: aluminum hydroxide gel (algeldrate) and magnesium hydroxide paste. Both components provide absorbent action. They absorb substances that adversely affect the lining of the stomach and intestines. Another therapeutic effect of these components is enveloping action. A powerful protective barrier is created on the surface of the walls of the stomach, which contributes to the uniform distribution of the drug. Such a protective layer provides a long-term effect of the active ingredients.

Aluminum and magnesium hydroxide neutralizing action on hydrochloric acid in the lumen of the stomach, resulting in the formation of aluminum and magnesium chloride. Subsequently, passing through the intestines, they are modified into alkaline salts. The proteolytic activity of pepsin decreases, and the environment becomes less aggressive. This is how it manifests antacid action medication. The ability to digest hydrochloric acid decreases and, accordingly, its adverse effect on the walls of the gastric tract decreases. There is an accelerated healing of erosive and ulcerative lesions, due to the elimination of negative factors. Another advantage is the absence of such a phenomenon as "acid rebound".

All aluminum compounds, including algeldrate, are characterized by a fixing effect. Magnesium hydroxide, on the contrary, manifests itself as an osmotic laxative, increasing the amount of water in the feces, accelerating their passage through the intestines. Sorbitol increases the secretion of bile, which laxative effect. Thus, these 2 substances complement each other, eliminating unpleasant consequences and causing a normal stool.

Almagel A

The only difference between Almagel A and the base suspension is that benzocaine is added to the main components. It is a local anesthetic.

Thanks to this substance, the patient is pronounced and rapid analgesic effect. Benzocaine, getting into the gastrointestinal tract, blocks the conduction of nerve impulses, so pain and discomfort disappear.

It should be remembered that the timing of the use of this type of medication is limited due to the side effects inherent in painkillers.

Almagel Neo

This type differs from the usual one in that it contains an additional component of simethicone. This element belongs to the group of carminatives, and according to the chemical structure it is an organosilicon compound.

Simethicone reduces the surface tension of gas bubbles in the digestive system, stimulating their rapid destruction and hindering further formation. Further, the released gases are absorbed into the intestinal wall and removed by peristalsis to the outside. This type of suspension acts gently and delicately, relieving dyspeptic disorders.

Any kind of drug Almagel can be found in a pharmacy. The price of the medicine varies from 150 to 300 rubles.

Indications for use

Indications for the use of all types of Almagel are similar, with the exception of a few points.

The use of antacid suspensions is prescribed:

• for the treatment of acute or chronic gastritis with normal or elevated levels of hydrochloric acid;
• in the treatment of ulcerative manifestations of the stomach and duodenum during periodic exacerbation;
• to carry out preventive measures;
• in the complex treatment of esophagitis, duodenitis, enteritis, hernia;
• to relieve food intoxication;
• to protect the walls of the stomach from the negative effects of non-steroidal anti-inflammatory drugs.

Besides green Almagel recommended for indigestion. This is the best option for heartburn attacks, to eliminate discomfort after malnutrition or the influence of harmful factors.

Doctors prescribe yellow Almagel A in cases where the pain symptom is pronounced, accompanied by vomiting and nausea. When intense pain subsides, accompanying signs disappear, the patient is recommended to switch to the classic suspension.

Effectively relieves bloating (flatulence) orange Almagel Neo, which is used for putrefactive or fermentative dyspepsia.

Almagel is used to relieve symptoms and treat various diseases of the gastrointestinal tract. Each type of medicine is responsible for its area of ​​action, carefully check with the gastroenterologist which Almagel is right for you.

Mode of application

Almagel comes in the form of a suspension and tablets. Before using the suspension, it is necessary to shake the contents of the vial so that it acquires a homogeneous composition.

The required dosage of the drug is determined by the gastroenterologist, depending on the age of the patient and the severity of the disease itself. Adults are prescribed from 5 to 10 ml. a single dose of the drug three times a day. Twice before meals for 30 minutes, and the last part is drunk before bedtime. If after a while there is no improvement in the patient's condition, the dosage is increased. The maximum allowable amount per day should not exceed 80 ml. (16 measuring spoons).

The dosage of Almagel for children should be strictly determined by the doctor. The following are just recommendations.

• Children under 10 years old: 1.7-3.5 ml.
• Children aged 10-15 years: 2.5-5 ml.
• Teenagers over 15 years old: 5-10 ml.

Application by adults

Suspension Almagel begins to act within 5 minutes, and the therapeutic effect lasts up to 2 hours. The liquid can be drunk only 30 minutes after taking the antacid. If, in addition to this medicine, you additionally drink other medicines, it is recommended to observe an interval between doses of at least one hour. During treatment, it is undesirable to drink antibiotics, antihistamines and heart medications.

Almagel can be combined with other means, but the expected result will not be the same. This also applies to drinks containing caffeine, which reduces the effectiveness of therapy.

Almagel A is taken in the same way as classic Almagel in green packaging. The instructions indicate the following indications: exacerbation of gastric and duodenal ulcers, enteritis, duodenitis, exacerbation of acute and chronic gastritis, diaphragmatic hernia, acid reflux, colitis, indigestion, epigastric pain with malnutrition, diabetes. If you have severe, sharp pain, nausea and vomiting, then an anesthetic suspension is better suited for therapy.

Almagel Neo is prescribed one hour after meals at a dosage of 5 ml. - this is the whole difference between this drug and others from the Almagel series. You can drink up to 60 ml per day. It differs from other preparations in its orange flavor. Allowed for children only from 10 years in the amount of 5 ml. for one visit.

special instructions

The medicine is produced in the form of a suspension - gel, which ensures its rapid and uniform distribution throughout the digestive system. The antacid begins to act gently, creating reliable protection and not leading to a sharp decrease in acidity, so problems with digestion of food are excluded.

If the drug is taken for a long time, phosphorus deficiency may occur, because it is able to remove it from the body. Therefore, the lack of phosphorus must be filled with special preparations, or a balanced diet.

Almagel Neo contains alcohol. For this reason, it should be taken with caution by people who have impaired liver function, have alcohol dependence, and suffer from epilepsy. The presence of alcohol does not affect the concentration of attention and the speed of reaction. It is prescribed even to patients whose activities determine perseverance and attentiveness.

Patients with fructose intolerance are not recommended to be treated with this medicine, since it contains sorbitol. It can provoke mucosal irritation and diarrhea in this category of people.

Read the instructions carefully before using the medicine.

Side effects

Side effects occur in isolated cases, if the doctor's instructions are not followed. As a rule, this is:

• allergic manifestations;
• nausea and vomiting;
• change in taste sensations;
• pain and spasms in the epigastrium;
• drowsiness and thirst;
• constipation or diarrhea.

When the patient suffers from renal insufficiency and consumes high doses of the suspension, this can lead to negative phenomena that are significantly different from the rest of the consequences. These include:

• the appearance of edema;
• an increase in the concentration of magnesium and aluminum in the blood, and calcium in the urine;
• pressure drop;
• dementia and encephalopathy.

Possibility of overdose

Long-term therapy in high doses of Almagel Neo may differ from treatment with other types of the drug by the occurrence of an overdose. The main symptoms are: increased fatigue and nervousness, changeable mood, slow breathing, numbness and muscle pain, inadequate reaction to events, hyperemia (redness) of the face. To eliminate such negative signs, you need to cleanse the body of an excess of medicine.

Such activities are carried out as: gastric lavage, stimulation of vomiting, laxatives and sorbents are given.

Contraindications

Here are the contraindications for all forms of Almagel:

• hypersensitivity to its components;
• Alzheimer's disease.

Caution should be taken during pregnancy. Let's just accept the usual form of Almagel. It is allowed to drink it for a maximum of 3 days and as a symptomatic remedy, as it can harm the development of the fetus.

This medication is considered one of the safest, because it is not absorbed into the circulatory system and does not harm the body during therapy. It quickly and effectively acts on an irritated stomach without stimulating metabolic disorders. All types of Almagel meet modern requirements, and their clinical effectiveness has been proven by many years of research.

Antacid drug with a component that reduces flatulence

Active ingredients

Magnesium hydroxide (magnesium hydroxide)
- simeticone
- algeldrate (aluminum hydroxide gel) (algeldrate)

Release form, composition and packaging

◊ Suspension for oral administration white or almost white, with an orange scent.

Excipients: hydrogen peroxide (solution 30%) - 0.495 mg, sorbitol - 474.6 mg, sodium saccharinate - 1.13 mg, hyetellose - 5.65 mg, citric acid monohydrate - 5.65 mg, ethyl parahydroxybenzoate - 7.9 mg, propyl parahydroxybenzoate - 3.4 mg, propylene glycol - 113 mg, macrogol 4000 - 452 mg, orange flavor - 2.26 mg, ethanol 96% - 113 mg, purified water - up to 5 ml.

170 ml - glass bottles (1) complete with a 5 ml measuring spoon - cardboard packs.
170 ml - polyethylene terephthalate bottles (1) complete with a 5 ml measuring spoon - cardboard packs.

pharmachologic effect

Combined remedy, the action of which is due to its constituent components. It has an antacid, adsorbing, enveloping, carminative effect. Algeldrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, lower the acidity of gastric juice, and bind bile acids. The laxative effect of magnesium hydroxide balances the ability of algeldrate to slow down intestinal motility. Simethicone hinders the formation of gas bubbles and contributes to their destruction. The gases released during this are absorbed by the intestinal walls and excreted from the body due to peristalsis.

Pharmacokinetics

Simethicone, due to physiological and chemical inertness, is not absorbed into organs and tissues and, after passing through the gastrointestinal tract, is excreted unchanged. Absorption of aluminum and magnesium ions in the intestine is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In chronic patients, the level of aluminum and magnesium in the blood may rise to toxic values ​​as a result of a violation of their excretion.

Indications

- acute gastritis;

- chronic gastritis with increased and normal secretory function of the stomach (in the acute phase);

- acute duodenitis, duodenogastric reflux;

- peptic ulcer of the stomach and duodenum (in the acute phase);

- symptomatic ulcers of the gastrointestinal tract of various origins;

- erosion of the mucous membrane of the upper gastrointestinal tract;

- gastroesophageal reflux, reflux esophagitis;

- acute pancreatitis, exacerbation of chronic pancreatitis;

- gastralgia, heartburn (after excessive consumption of ethanol, nicotine, coffee, taking medications; incorrect diet that adversely affects the functioning of the gastrointestinal tract);

- flatulence;

- fermentative or putrefactive dyspepsia.

Contraindications

- chronic renal failure;

- hypophosphatemia;

- children's age up to 10 years;

- congenital fructose intolerance;

- hypersensitivity.

Carefully: lactation period, liver disease, alcoholism, traumatic brain injury, brain disease, epilepsy, children and adolescents from 10 to 18 years.

Dosage

Adults.

Inside, 2 scoops of suspension with orange flavor 4 times / day 1 hour after meals and in the evening before bedtime. If necessary, a single dose can be increased to 4 scoops, but the maximum daily dose should not exceed 12 scoops.

Children over 10 years old.

The dosage is determined by the attending physician - usually 1/2 dose for adults.

The course of treatment - no more than 4 weeks. Before taking the suspension must be homogenized by shaking the vial. It is advisable to take Almagel Neo undiluted. It is not recommended to take liquid within half an hour after taking the drug.

Side effects

Allergic reactions, nausea, vomiting, changes in taste, constipation, diarrhea. With prolonged use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis, impaired renal function. In patients with concomitant renal failure - thirst, lowering blood pressure, hyporeflexia.

Overdose

Symptoms. Prolonged use of high doses can lead to the development of hypermagnesemia, which is characterized by rapid fatigue, facial flushing, emaciation, muscle weakness and inappropriate behavior. There may also be signs of metabolic alkalosis: mood changes, mental impairment, numbness or, nervousness and fatigue, slow breathing, unpleasant taste sensations.

urgent measures. It is necessary to immediately take measures to quickly remove the drug - gastric lavage, stimulation of vomiting, intake of activated charcoal.

drug interaction

Neo reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamine receptor blockers, beta-blockers, diflunisal, ketoconazole and itraconazole, tetracycline antibiotics and quinolones, azithromycin, cefpodoxime, pivampicillin, rifampicin, indirect anticoagulants , fexofenadine, dipyridamole, zalcitabine, chenodeoxycholic and ursodeoxycholic acids, penicillamine and lansoprazole.

M-anticholinergics, slowing down the emptying of the stomach, enhance and lengthen the effect of the drug.

special instructions

The interval between taking Almagel Neo and other medicines should be 1-2 hours.

With long-term use, sufficient intake of phosphorus from food should be ensured.

Due to the lack of data from controlled clinical trials, breastfeeding women should take Almagel Neo only after consulting a doctor.

One measuring spoon (5 ml) of the drug contains 0.113 g, as a result of which complications may occur in patients With diseases of the liver and brain, in those suffering from alcoholism and epilepsy, in pregnant women and children under 18 years of age.

The daily dose of the drug (8 scoops) contains 0.904 g of ethyl alcohol, the maximum daily dose of the suspension (12 scoops) contains 1.356 g of ethyl alcohol.

One measuring spoon (5 ml) of Almagel Neo contains 0.475 g of sorbitol, which is contraindicated in congenital fructose intolerance and can cause stomach irritation and diarrhea.

It does not adversely affect the ability to drive vehicles and work with mechanisms that require increased concentration of attention and speed of psychomotor reactions.

Terms of dispensing from pharmacies

The drug is approved for use as a means of OTC.

Terms and conditions of storage

Store in a place protected from light, out of the reach of children, at a temperature not exceeding 25°C. Do not freeze! Shelf life - 2 years. Do not use after the expiry date stated on the packaging.