What is Magnelis B6 used for: replenishing vitality. Magnelis B6 - instructions, use, indications, contraindications, action, side effects, analogs, dosage, composition Magnelis B6 contraindications

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The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Magne B6 is a drug that replenishes the deficiency of magnesium and vitamin B 6 in the human body, regardless of the reasons that provoked it. The drug is used for the prevention and treatment of magnesium deficiency and related disorders, such as sleep disorders, nervous excitability, mental or physical fatigue, pain and muscle spasms, anxiety attacks with hyperventilation, as well as asthenia.

Composition, release forms and varieties of Magne B6

Currently, the drug is available in two varieties - Magne B6 And Magne B6 forte. In the pharmaceutical market of some CIS countries (for example, in Kazakhstan), Magne B6 forte is sold under the name Magne B6 Premium. The difference in names is due only to the marketing work of the manufacturing company, since Magne B6 Forte and Magne B6 Premium are absolutely identical drugs. Magne B6 and Magne B6 forte differ from each other only in the dosage of active ingredients, of which the second preparation contains twice as much. Otherwise, there are no differences between the varieties of the drug.

Magne B6 is available in two dosage forms:

  • Tablets for oral administration;
  • Oral solution.
Magne B6 forte is available in a single dosage form - tablets for oral administration.

The composition of tablets and solution of both varieties of Magne B6 as active ingredients includes the same substances - magnesium salt and vitamin B 6, the amount of which is reflected in the table.

Active components of Magne B6 tablets (amount per tablet) Active components of Magne B6 forte tablets (amount per tablet) Active components of Magne B6 solution (amount per ampoule)
Magnesium lactate dihydrate 470 mg, corresponding to 48 mg of pure magnesiumMagnesium citrate 618.43 mg, which corresponds to 100 mg of pure magnesiumMagnesium lactate dihydrate 186 mg and magnesium pidolate 936 mg, equivalent to 100 mg pure magnesium
Vitamin B6 in the form of pyridoxine hydrochloride – 5 mgVitamin B6 in the form of pyridoxine hydrochloride – 10 mg

Thus, as can be seen from the table, one tablet of Magne B6 forte contains the same amount of active substances as one full ampoule of solution (10 ml). And Magne B6 tablets contain two times less active substances compared to a full ampoule of solution (10 ml) and Magne B6 forte. This should be kept in mind when calculating dosages for taking the drug.

Auxiliary components of both varieties of Magne B6 are also reflected in the table.

Excipients of Magne B6 tablets Excipients of Magne B6 forte tablets Excipients of Magne B6 solution
Titanium dioxideHypromelloseSodium disulfite
Carnauba waxTitanium dioxideSodium saccharinate
Acacia gumLactoseCherry caramel flavor
KaolinMacrogolPurified water
CarboxypolymethyleneMagnesium stearate
Magnesium stearateTalc
Sucrose
Talc

Magne B6 and Magne B6 forte tablets have the same oval, biconvex shape and are painted in a shiny white color. Magne B6 is packaged in cardboard boxes of 50 pieces, and Magne B6 forte - 30 or 60 tablets.

Magne B6 oral solution is bottled in sealed ampoules of 10 ml. The package contains 10 ampoules. The solution is colored brown transparent and has a characteristic caramel smell.

Therapeutic effect

Magnesium plays an important role in various physiological processes in the body, ensuring the process of transmitting impulses from nerve fibers to muscles, as well as contractions of muscle fibers. In addition, magnesium reduces the excitability of nerve cells and ensures the activation of a number of enzymes, under the influence of which cascades of important biochemical metabolic reactions occur in various organs and tissues.

Magnesium deficiency can develop due to the following reasons:

  • Congenital pathology of metabolism, in which this element is poorly absorbed in the intestines from food;
  • Insufficient intake of the element into the body, for example, due to malnutrition, starvation, alcoholism, parenteral nutrition;
  • Impaired absorption of magnesium in the digestive tract due to chronic diarrhea, gastrointestinal fistulas or hypoparathyroidism;
  • Loss of large amounts of magnesium due to polyuria (urine excretion in a volume of more than 2 liters per day), taking diuretics, chronic pyelonephritis, renal tubular defects, primary hyperaldosteronism or the use of Cisplastin;
  • Increased need for magnesium during pregnancy, stress, taking diuretics, as well as during high mental or physical stress.
Vitamin B6 is a necessary structural element of enzymes that ensure the occurrence of various biochemical reactions. Vitamin B6 is involved in the metabolic process and in the functioning of the nervous system, and also improves the absorption of magnesium in the intestines and facilitates its penetration into cells.

Magne B6 - indications for use

Both varieties of Magne B6 have the same following indications for use:
1. Identified and confirmed by laboratory test data, magnesium deficiency, in which a person has the following symptoms:
  • Irritability;
  • Sleep disorders;
  • Spasms of the stomach and intestines;
  • Heartbeat;
  • Muscle spasms and pain;
  • Tingling sensation in muscles and soft tissues.
2. Prevention of the development of magnesium deficiency against the background of an increased need for this element (pregnancy, stress, malnutrition, etc.) or its increased removal from the body (pyelonephritis, taking diuretics, etc.).

Magne B6 - instructions for use

Magne B6 tablets

Magne B6 in tablet form is intended only for adults and children over 6 years of age. Children under 6 years of age should be given the drug in the form of an oral solution.

The tablets must be taken with meals, swallowed whole, without biting, chewing or crushing in any other way, and with a glass of still water.

The dosage of Magne B6 is determined by the person’s age:

  • Adults and adolescents over 12 years of age – take 6–8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day);
  • Children over 6 years old with a body weight of more than 20 kg - take 4-6 tablets per day (2 tablets 2-3 times a day).
The indicated daily amount of Magne B6 is divided into 2 - 3 doses per day, keeping approximately equal intervals between them.

Dosages of Magne B6 forte are determined by the person’s age:

  • Adults and adolescents over 12 years of age - take 3-4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day);
  • Children 6 - 12 years old - take 2 - 4 tablets per day (1 tablet 2-3 times a day or 2 tablets 2 times a day).
The total indicated daily dosage of the drug must be divided into 2 - 3 doses.

The average duration of treatment is 3 – 4 weeks. If the drug is taken to eliminate magnesium deficiency, then the course of treatment is completed when, according to the results of laboratory tests, the concentration of this element in the blood is normal. If the drug is taken for prophylactic purposes, the course of treatment is 2–4 weeks.

special instructions

In case of moderate and mild renal failure, the drug should be used with caution, constantly monitoring the level of magnesium in the blood, since due to the low rate of excretion of the drug by the kidneys, there is a risk of developing hypermagnesemia (increased concentration of magnesium in the blood). If renal failure is severe and CC (according to the Rehberg test) is less than 30 ml/min, then Magne B6 is contraindicated for use in any form (both tablets and solution).

Children aged 1 – 6 years should be given Magne B6 only in solution form. Children over 6 years of age who weigh more than 20 kg can be given Magne B6 in tablet form (including Magne B6 forte). But if a child over 6 years old has a body weight of less than 20 kg, then he cannot be given the drug in tablets; in this case, a solution should be used.

If a person has a severe degree of magnesium deficiency, then before taking Magne B6, several intravenous injections of appropriate drugs should be made.

If a person has a combined deficiency of calcium and magnesium, then it is first recommended to take a course of Magne B6 to eliminate the deficiency of magnesium, and only after that begin to take various dietary supplements and medications to normalize calcium levels in the body. This recommendation is due to the fact that in conditions of magnesium deficiency, calcium entering the body is very poorly absorbed.

If a person often drinks alcoholic beverages, laxatives, or constantly endures heavy physical or mental stress, then he can take Magne B6 to prevent magnesium deficiency in the body without any special tests. In this case, the usual preventive course is 2–3 weeks, and it can be repeated every 2–3 months.

Magne B6 solution contains sulfite as excipients, which can increase the manifestations of allergies, which must be kept in mind and taken into account by people prone to hypersensitivity reactions.

When taking the drug in high dosages (more than 20 tablets of Magne B6 forte and more than 40 tablets or 40 ampoules of Magne B6) for a long time, there is a risk of developing axonal neuropathy, which is manifested by numbness, impaired pain sensation, tremor of the arms and legs and gradually increasing coordination disorder movements. This disorder is reversible and disappears completely after discontinuation of the drug.

If, despite taking Magne B6, the symptoms of magnesium deficiency (excitability, muscle cramps, irritability, insomnia, fatigue) do not decrease or go away, then you should stop using the drug and consult a doctor to clarify the diagnosis.

Impact on the ability to operate machinery

Neither tablets nor Magne B6 solution affect a person’s ability to control mechanisms, therefore, while taking any form of the drug, you can engage in various activities that require high reaction speed and concentration.

Overdose

An overdose of Magne B6 is possible, but, as a rule, this occurs against the background of renal failure. In people who do not suffer from kidney disease, an overdose of Magne B6 is usually not observed.

Symptoms of an overdose of Magne B are the following:

  • Reduced blood pressure;
  • Nausea;
  • CNS depression;
  • Reduced severity of reflexes;
  • Changes on the ECG;
  • Respiratory depression up to paralysis;
  • Anuria (lack of urine).
To treat an overdose of Magne B6, it is necessary to give a person diuretics in combination with large amounts of water and rehydration solutions (for example, Regidron, Trisol, Disol, etc.). If a person suffers from renal failure, then hemodialysis or peritoneal dialysis is necessary to eliminate the overdose.

Interaction with other drugs

Magne B6 reduces the severity of the therapeutic effect of Levodopa. Therefore, it is recommended to avoid the combined use of Levodopa with Magne B6, however, if there is an urgent need to take these drugs, then peripheral dopa decarboxylase inhibitors (Benserazide, etc.) should also be prescribed. In other words, the combination of Levodopa and Magne B6 is possible only with the additional use of a third drug from the group of dopa decarboxylase inhibitors.

Calcium and phosphate salts impair the absorption of magnesium in the intestine, so they are not recommended for use simultaneously with Magne B6.

Magne B6 reduces the absorption of tetracyclines (Tetracycline, Oxytetracycline, Chlortetracycline, Doxycycline) in the intestine, so an interval of at least 2 to 3 hours should be maintained between taking these drugs. That is, Magne B6 should be taken either 2 - 3 hours before or 2 - 3 hours after taking a tetracycline antibiotic.

Magne B6 weakens the effects of thrombolytic agents (Streptokinase, Alteplase, etc.) and anticoagulants (Warfarin, Thrombostop, Phenilin, etc.), and impairs the absorption of iron preparations (for example, Fenyuls, Ferrum Lek, Sorbifer Durules, etc. .).

Magne B6 during pregnancy

Magne B6 is approved for use during pregnancy, since long-term observations and experimental studies have not revealed any negative effects of this drug on the fetus and mother.

Magne B6 is widely prescribed to pregnant women, since its benefits are obvious in almost all cases. Thus, magnesium, which is part of the drug, helps reduce excitation in the central nervous system, due to which the woman becomes calmer, nervousness, moodiness, mood swings, etc. disappear. Of course, the calmness of the expectant mother has a positive effect on the child.

Vitamin B6, also included in the drug, is necessary for normal growth and development of the nervous system and heart of the fetus. Against the background of vitamin B6 deficiency, the fetus may develop malformations of the heart, its valve apparatus or the central nervous system. Magne B6 prevents such pregnancy complications.

Thus, it is obvious that Magne B6 improves not only the physical condition of a pregnant woman and eliminates uterine hypertonicity, but also has a positive effect on the emotional background and relieves unnecessary stress.

However, Magne B6 is prescribed to almost all pregnant women in fairly long courses, even if the woman does not have a threat of miscarriage, hypertension, tics, etc. This practice is due to the fact that during pregnancy the consumption and need for magnesium doubles, and quite often a woman does not receive the required amount of the microelement from food or vitamins, as a result of which she develops certain symptoms of microelement deficiency. Therefore, doctors consider the prophylactic prescription of Magne B6 to be justified in order to prevent deficiency of magnesium and vitamin B6.

remember, that Symptoms of magnesium deficiency are:

  • Spasms, cramps, muscle tics, nagging pain in the lower back or lower abdomen;
  • Dizziness, headaches, sleep disorders, irritability;
  • Arrhythmia, high or low blood pressure, palpitations, heart pain;
  • Nausea, vomiting, alternating constipation with diarrhea, cramps and abdominal pain;
  • Tendency to edema, low body temperature, constant chilliness.
Similar symptoms occur in a large number of pregnant women, which allows us to conclude that magnesium deficiency is widespread during pregnancy. Knowing this state of affairs, gynecologists managing pregnancy prescribe Magne B6 to women in regular courses of 3 to 4 weeks, even if this particular pregnant woman has not yet fully developed symptoms of magnesium deficiency.

During pregnancy, it is optimal to take 2 tablets of Magne B6 or 1 tablet of Magne B6 forte 3 times a day with meals.

Magne B6 for children

Magne B6 is prescribed to children to eliminate or prevent magnesium deficiency. In some cases, the drug is prescribed “just in case,” since clinical observations have shown that taking Magne B6 has a positive effect on the general condition of the child, who sleeps better, becomes calmer, more attentive, more diligent, and is less likely to be capricious and nervous. Of course, such effects are assessed very positively by both parents and pediatricians, and therefore Magne B6 is often prescribed to children who do not have magnesium deficiency, but adults want to make them calmer and less excitable. Despite the beneficial effects of Magne B6, it is not recommended to use the drug without a doctor’s prescription and supervision, especially for children 1–6 years old.

Magne B6 is available in two dosage forms - tablets and oral solution. Tablets can only be given to children over 6 years old, provided that their body weight has reached 20 kg or more.

The dosage of Magne B6 for children is determined by their age and body weight:

  • Children aged 1 – 6 years with a body weight of 10 – 20 kg– take 1 – 4 ampoules per day, having previously calculated the exact dosage based on body weight, based on the ratio of 10 – 30 mg of magnesium per 1 kg of weight per day;
  • Children aged 6 – 12 years, weighing more than 20 kg– take 1 – 3 ampoules per day (1/3 – 1 ampoule 3 times a day) or 4 – 6 tablets per day (2 tablets 2 – 3 times a day);
  • Teenagers over 12 years old– take 2 – 4 ampoules per day (1 ampoule 2-3 times a day or 2 ampoules 2 times a day) or 6 – 8 tablets per day (2 tablets 3 times a day or 4 tablets 2 times a day).
Clarifying the dosage not only by age, but also by body weight is very important. The fact is that even if the child is one year old, but his weight is less than 10 kg, then he cannot be given Magne B6 solution. Also, you should not give pills to a child if he is 6 years old but weighs less than 20 years. In this case, a six-year-old child is given a solution in dosages for 1 to 6 years.

For children 1–6 years old, it is recommended to calculate the dosage individually based on body weight. For example, a child’s weight is 15 kg, which means he can be given a solution in a dosage of 10 * 15 = 150 mg, or 30 * 15 = 450 mg per day (calculation is based on the amount of magnesium). Since one full ampoule contains 100 mg of magnesium, 150 mg and 450 mg correspond to 1.5 or 4.5 ampoules. When the calculation results in an incomplete number of ampoules, it is rounded to whole numbers. That is, in our example, 1.5 ampoules are rounded to 2, and 4.5 - to 4, since the maximum permissible dosage for a child 1 - 6 years old is 4 ampoules.

Magne B6 forte can be given to children over 6 years old, provided that their body weight is more than 20 kg. The dosage of Magne B6 forte for children of different ages is as follows:

  • Teenagers over 12 years old– take 3 – 4 tablets per day (1 tablet 3 times a day or 2 tablets 2 times a day);
  • Children 6 – 12 years old– take 2 – 4 tablets per day (1 tablet 2-3 times a day or 2 tablets 2 times a day).
The indicated daily amount of Magne B6 and Magne B6 forte should be divided into 2 - 3 doses and drunk with meals. It is optimal to give the child all 2 - 3 doses of the drug before 17.00. The solution from the ampoules for administration is first diluted in half a glass of still water, and the tablets are washed down with a glass of water.

The course of use of Magne B6 for children without confirmed magnesium deficiency is 2–3 weeks. For children with identified and laboratory-confirmed magnesium deficiency, the drug is given until the level of the mineral in the blood rises to normal values.

  • Age under 6 years (only for Magne B6 and Magne B6 forte tablets);
  • Age under 1 year (for oral solution);
  • Fructose intolerance (for Magne B6 and Magne B6 forte tablets);
  • Sucrase-isomaltase deficiency (for Magne B6 and Magne B6 forte tablets);
  • Glucose-galactose malabsorption syndrome (for Magne B6 and Magne B6 forte tablets);
  • Taking Levodopa;
  • Increased individual sensitivity to the components of the drug.
  • Analogs

    Magne B6 has two types of analogues - these are synonyms and, in fact, analogues. Synonyms include medications that contain the same active substances as Magne B6. Analogues include drugs that have a similar spectrum of therapeutic action, but contain other active substances.

    On the Russian pharmaceutical market Magne B6 has only three synonymous drugs:

    • Magnelis B6;
    • Magwit;
    • Magnesium plus B6.
    On the Ukrainian pharmaceutical market In addition to those indicated, there are two more synonymous drugs - Magnicum and Magnelact. Previously, Magnelact was also sold in Russia, but its registration has now expired.

    The following drugs are analogues of Magne B6:

    • Additiva magnesium effervescent tablets;
    • Vitrum Mag chewable tablets;
    • Magne Positive tablets;
    • Magne Express granules for resorption;
    • Magnerot tablets;
    • Magnesium-Diasporal 300 granules for the preparation of solution for oral administration;
    • Magnesium plus tablets.

    Cheap analogues of Magne B6

    The following drugs are cheaper synonyms compared to Magne B6:
    • Magnelis B6 – 250 – 370 rubles for 90 tablets;
    • Magnesium plus B6 – 320 – 400 rubles for 50 tablets.
    The cost of Magnelis B6 and Magnesium plus B6 is almost two or more times lower than that of Magne B6.

    The only cheaper analogue of Magne B6 is Vitrum Mag - 270 - 330 rubles for 30 tablets.

    The main task of Magnelis B6 is to prevent magnesium deficiency in the body. Vitamin B6, which is also included in its composition, helps the body absorb magnesium from a synthetic preparation.

    Importance of Magnesium for Health

    Magnesium- one of the most important microelements for human well-being. It is needed at all stages of protein synthesis in the body, converts creatine phosphate into adenosine triphosphate(ATP). ATP is the source of energy in all living cells in the body.

    Magnesium ensures the smooth transmission of impulses from the brain to the muscles through the nervous system, helping muscles contract effectively.

    During pregnancy, the daily need for magnesium increases. The growth and development of an embryo requires a lot of energy.

    Magnesium deficiency can be corrected by eating plenty of green vegetables and fruits. Sometimes it can be difficult to eat enough of these foods. In such cases, doctors prescribe this microelement in tablets, for example, Magnelis B6.

    What does magnesium deficiency lead to?

    Why take Magnelis B6? First of all, in order to prevent a lack of magnesium in the body. This condition is dangerous for the normal functioning of the body. Without it, it is more difficult for the body to cope with stress; the nervous system is exhausted due to constant tension. It stimulates the intestines, allowing you to avoid such a common problem in most pregnant women - constipation.

    In addition, an insufficient amount of magnesium in the body manifests itself in one of the following ways:


    For pregnant women in the early stages, additional intake of medications and vitamins that contain increased amounts of magnesium is especially important. In most cases, it is prescribed to everyone who registers for pregnancy for prevention along with Duphaston (or its analogue, Utrozhestan).

    Why should pregnant women take magnesium?

    How Magnelis B6 helps during pregnancy:


    Duphaston is a synthetic analogue of progesterone. This is a hormone produced in the second phase of the menstrual cycle. Why do pregnant women need it? Its main task is to support the ongoing pregnancy. Therefore, it is prescribed to avoid miscarriage caused by progesterone deficiency.

    Why is Magnelis B6 prescribed together with Duphaston?

    Gynecologists prescribe Duphaston to most pregnant women to avoid the development of progesterone deficiency.

    One of its actions is to flush out magnesium and calcium from the body.

    By the way, almost all hormonal drugs, even oral contraceptives, have the same effect. Therefore, it is recommended to regularly take a course of vitamins to prevent a deficiency of these microelements in the body.

    What is included in Magnelis B6?

    Magnelis B6 contains magnesium itself in the form of magnesium lactate and pyridoxine hydrochloride, better known as vitamin B6.

    The daily requirement of a pregnant woman for magnesium is - 350 to 400 mg, and in vitamin B6 - from 2 to 2.2 mg.

    At first glance, it may seem that one tablet per day will be quite enough to meet the body's need for these substances. But this is not entirely true, because:

    • The instructions indicate the content of magnesium lactate, not magnesium lactate itself in its pure form. Its equivalent content is approximately 10 times less;
    • the body does not absorb the contents of the tablet 100%, some of the magnesium simply leaves it unchanged;
    • Most of vitamin B6 is spent on the body's absorption of magnesium, rather than replenishing the content of the vitamin itself.

    Why is vitamin B6 needed?

    Vitamin B6 deficiency has almost the same symptoms as magnesium deficiency. Hair falls out, a persistent feeling of fatigue occurs, the skin becomes dry and cracks often appear in the corners of the lips and on the heels, the limbs periodically go numb.

    During pregnancy, it is necessary to promptly compensate for the lack of vitamins.

    Vitamin B6 promotes better absorption of magnesium by the body.

    That is why most drugs used as a source of magnesium also contain vitamin B6.

    How vitamin B6 is beneficial for the health of the expectant mother and fetal development:

    • it is involved in metabolism and energy production in cells;
    • improves the absorption of magnesium by body cells after it enters the stomach;
    • does not allow blood glucose levels to change sharply;
    • helps the body tolerate stress more easily, strengthens the nervous system, and helps to remain calm in difficult situations.

    All these properties and actions that Magnelis B6 has make it an almost indispensable drug not only during pregnancy, but also during its planning.

    Contraindications

    Like most medications, Magnelis B6 has a number of contraindications. It should be prescribed with caution to patients with kidney disease and moderate renal failure. In case of severe renal failure, taking Magnelis B6 is prohibited. Therefore, pregnant women take this drug without fear.

    Magnelis B6 is a medicine aimed at restoring the deficiency of such an important element as magnesium in the body.

    What is the composition and release form of the medication Magnelis B6?

    The drug Magnelis B6 is produced in white tablets, they are round, biconvex, where the active components are magnesium lactate and pyridoxine hydrochloride.

    The excipients of this product are represented by the following components: sucrose, povidone, collidon SR, talc, added magnesium stearate, in addition, sodium carboxymethylcellulose, as well as kaolin, gelatin, titanium dioxide, acacia gum, white beeswax and carnauba.

    The tablets are packaged in contour packs of 10 pieces, in addition, the product is supplied to the pharmaceutical market in jars made of polymer material, where there are 60 and 90 tablet forms. The medicine is sold without a prescription. The shelf life is no more than two years, which is reflected on the medicine box.

    What is the effect of Magnelis B6 tablets?

    The drug Magnelis B6 replenishes magnesium deficiency; this element is vital for humans, as it is involved in many biochemical processes that continuously occur in the human body.

    Magnesium is found in all tissues of the body, it is necessary for the full functioning of cells, helps regulate the transmission of nerve impulses, takes part in muscle contraction, and also has an antiplatelet and antispasmodic effect.

    A lack of magnesium can be observed in case of malnutrition, as well as when the body’s need for this element increases, for example, in a stressful situation, with increased physical and mental stress, during pregnancy, and also when using diuretics.

    The second active compound of Magnelis B6 is pyridoxine or vitamin B6, which is involved in the regulation of nervous system metabolism and also promotes better absorption of magnesium from the digestive tract.

    What are the indications for use of Magnelis B6?

    The instructions for use of the drug Magnelis B6 are prescribed for the treatment of magnesium deficiency, and the medicine must be used as prescribed by a doctor.

    What are the contraindications for use of Magnelis B6?

    There are some contraindications when it is prohibited to use Magnelis B6, I will list them:

    Severe renal failure;

    Hypersensitivity to the components of the drug;

    Presence of phenylketonuria;

    The drug is not prescribed to children under six years of age.

    The drug is prescribed with caution for moderate kidney pathology.

    What is the use and dosage of Magnelis B6?

    For adults, Magnelis B6 is recommended to use a maximum of eight tablets per day, washed down with water. It is recommended to divide the daily dosage into two or three times. Children over six years of age are prescribed 4 to 6 tablet forms.

    Treatment should be discontinued after normalization of magnesium levels in the bloodstream. The drug is taken during meals. It is worth noting that Magnelis B6 can reduce the absorption of medications of the tetracycline group; accordingly, it is recommended to separate the use of these medications with a three-hour break.

    Overdose from Magnelis B6

    With normal kidney function, an overdose will not cause toxic reactions. If the patient takes a significant amount of the drug with impaired renal function, he may develop the following symptoms: a drop in blood pressure, nausea and vomiting are characteristic, there is some slowing of reflexes, anuria occurs, respiratory depression may occur, in addition, in more severe cases, coma and cardiac arrest.

    If an overdose of the drug develops, the patient is given rehydration therapy, forced diuresis, in addition, hemodialysis is necessary, and peritoneal dialysis is also effective.

    What are the side effects of Magnelis B6?

    The drug Magnelis B6, which we continue to talk about on this page www.site, can cause side effects of the following nature: pain develops in the abdomen, intestinal motility is disrupted, resulting in constipation, flatulence is typical, as well as vomiting and nausea.

    In addition to the listed side effects, the patient experiences allergic reactions; they can be expressed in a dermatological form, that is, a rash appears on the skin, swelling and redness occur. In such a situation, it is necessary to consult a qualified specialist.

    special instructions

    If it is necessary to use the drug Magnelis B6 in patients with endocrine pathology, in particular with diabetes, it is necessary to warn the patient that the tablets contain a certain amount of sucrose as an auxiliary compound.

    If the drug is stored incorrectly, its physicochemical characteristics may be disrupted, which will result in a change in the color of the tablets; in addition, they will crumble easily and lose their shape. In such a situation, the use of such a medication is contraindicated.

    How to replace Magnelis B6, what analogues should I use?

    Currently, there are no analogues of Magnelis B6.

    Conclusion

    Magnelis B6 should only be used on the recommendation of a qualified doctor.

    The drug Magnelis B6 replenishes magnesium deficiency in the body. Instructions for use suggest taking tablets for conditions associated with magnesium deficiency. Reviews from patients and recommendations from doctors indicate that this drug helps with muscle cramps.

    Release form and composition

    Magnelis B6 is available in tablets for oral use, convex on both sides, coated with a white protective coating.

    The drug is packaged in blisters of 10 pieces, 3 or 5 blisters in a cardboard box, or 100 pieces in plastic jars with attached instructions.

    Each tablet of Magnelis B6 contains 470 mg of magnesium lactate and 5 mg of pyridoxine hydrochloride (vitamin B6). In addition to the main active ingredients, the drug contains a number of excipients.

    They also sell an enhanced form of the drug Magnelis B6 Forte. The instructions indicate double the content of active elements in this preparation.

    pharmachologic effect

    Magnelis B6 is a drug that replenishes magnesium deficiency. Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells. Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, and has antispasmodic, antiarrhythmic and antiplatelet effects.

    The body receives magnesium through food. A lack of magnesium in the body can occur when the diet is disrupted or when the need for magnesium increases (with increased physical and mental stress, stress, pregnancy, use of diuretics).

    Pyridoxine (vitamin B6) is involved in many metabolic processes and in the regulation of nervous system metabolism. Improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

    Why take Magnelis B6 (forte)?

    Indications for the use of the drug include magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as:

    • muscle spasms or pain, tingling sensation in the muscles;
    • increased fatigue;
    • gastrointestinal cramps;
    • minor sleep disturbances;
    • cardiopalmus;
    • increased irritability.

    Instructions for use

    According to the instructions, Magnelis B6 is prescribed to patients over 16 years of age, 2 tablets of the drug 3-4 times a day, which depends on the severity of magnesium deficiency. The drug can be taken regardless of food, crushed if necessary and washed down with plenty of water.

    The duration of the course of therapy is determined by a specialist and continues until the level of magnesium in the blood serum normalizes.

    Contraindications

    • phenylketonuria;
    • children under 6 years of age;
    • hypersensitivity to the components of the drug;
    • severe renal failure (creatinine clearance less than 30 ml/min).

    Side effects

    Possible adverse reactions from the digestive system:

    The development of allergic reactions may also occur.

    Children, pregnancy and breastfeeding

    Clinical experience has not revealed any fetotoxic or teratogenic effects of the drug. Magnelis B6 can be used during pregnancy only as prescribed by a doctor. Magnesium is excreted in breast milk.

    The use of the drug should be avoided during lactation and breastfeeding. Contraindicated in children under 6 years of age.

    special instructions

    Patients with diabetes should take into account that the tablets contain sucrose as an auxiliary component. With frequent consumption of alcohol, laxatives, intense mental and physical stress, the need for magnesium increases, which can cause the development of magnesium deficiency in the body. In cases of concomitant calcium deficiency, magnesium deficiency should be corrected before taking calcium supplements.

    Drug interactions

    When using the drug Magnelis B6 simultaneously with Tetracycline, the absorption of the latter is reduced, as a result of which the therapeutic effect will be insufficient. If drug interactions are necessary, an interval of at least 3 hours should be maintained.

    Magnesium prevents iron from being fully absorbed by the walls of the small intestine, so it is not recommended to combine Magnelis B6 with medications to treat anemia.

    Under the influence of Pyridoxine, which is part of the drug, the therapeutic effect of Levodopa is inhibited.

    Drug analogues

    Analogues are determined by structure:

    1. Pikovit Complex.
    2. Magne B6 forte.
    3. Magnelact.
    4. Magnesium plus.
    5. Supradin Kids Junior.
    6. Additive Magnesium.
    7. Osteocare solution.
    8. Vitrum Mag.
    9. Asparkam Farmak.
    10. Beauty tabs Elegant with calcium.
    11. Multi tabs Active.
    12. Vitrum forte Osteomag.
    13. Magne B6.

    Vacation conditions and price

    The average price of Magnelis B6 (tablets No. 50) in Moscow is 305 rubles. The medicine can be freely purchased in pharmacies without a prescription from a doctor.

    The optimal storage temperature for the drug should not be higher than 25 degrees. Keep tablets in a dry place away from children. The shelf life is 3 years from the date of manufacture, which is indicated on the packaging.

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    INSTRUCTIONS
    on the use of the drug
    for medical use

    Registration number:

    LSR-008492/08

    Tradename:

    Magnelis ® B 6.

    Dosage form:

    Film-coated tablets.

    Description:
    The tablets are round, biconvex, white or almost white coated.

    Compound.

    Each tablet contains magnesium lactate - 470 mg and pyridoxine hydrochloride - 5 mg
    Excipients:
    Core: sucrose - 27.4 mg, kaolin - 41.0 mg, acacia gum - 25.0 mg, collidon SR [polyvinyl acetate 80%, povidone 19%, sodium lauryl sulfate 0.8%, silicon dioxide 0.2% ] -34.0 mg, magnesium stearate - 6.8 mg, carmellose sodium - 34.0 mg, talc - 6.8 mg.
    Shell: sucrose - 166.7 mg, kaolin - 54.0 mg, gelatin - 0.9 mg, acacia gum - 4.0 mg, beeswax - 0.4 mg, titanium dioxide - 9.0 mg, talc - 15.0 mg.

    Pharmacotherapeutic group:

    Magnesium preparation.

    ATX code:А12СС01

    Pharmacological properties

    Replenishes magnesium deficiency.
    Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells. Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, and has antispasmodic, antiarrhythmic and antiplatelet effects.
    The body receives magnesium through food. A lack of magnesium in the body can occur when the diet is disrupted or when the need for magnesium increases (with increased physical and mental stress, stress, pregnancy, use of diuretics).
    Pyridoxine (vitamin B 6) is involved in many metabolic processes and in the regulation of nervous system metabolism. Vitamin B 6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.
    Serum magnesium content:
  • from 12 to 17 mg/l (0.5-0.7 mmol/l) indicates moderate magnesium deficiency.
  • below 12 mg/l (0.5 mmol/l) indicates severe magnesium deficiency.
  • Pharmacokinetics
    Absorption of magnesium in the gastrointestinal tract is 50% of the dose taken orally. It is excreted primarily through the kidneys. In the kidneys, after glomerular filtration of 70% of the magnesium present in the plasma, it is reabsorbed by the renal tubules in a proportion of 95% - 97%.

    Indications for use

    Established magnesium deficiency, isolated or associated with other deficiency conditions.

    Contraindications

    Hypersensitivity to the components of the drug, severe renal failure (creatinine clearance less than 30 ml/min), phenylketonuria.
    Childhood- up to 6 years.
    Carefully: with moderate renal failure, as there is a risk of developing hypermagnesemia.

    Pregnancy and breastfeeding period

    Pregnancy: Clinical experience has not revealed fetotoxic or fetal malformation effects. Magnelis ® Wb can be used during pregnancy only as directed by a doctor.
    Lactation period: Magnesium passes into breast milk. The use of the drug should be avoided during lactation and breastfeeding.

    Directions for use and doses

    Before taking the drug, you should consult your doctor. Adults are recommended to take 6-8 tablets per day. Children over 6 years old (body weight more than 20 kg) 4-6 tablets per day. The daily dose should be divided into 2-3 doses, taken during meals with a glass of water.
    Treatment should be stopped after normalization of magnesium concentration in the blood.

    Side effect

    From the gastrointestinal tract: abdominal pain, constipation, nausea, vomiting, flatulence.
    Allergic reactions: Allergic reactions to the components of the drug are possible.

    Overdose

    With normal renal function, oral magnesium does not cause toxic reactions. Magnesium poisoning can develop due to kidney failure. Toxic effects mainly depend on serum magnesium levels.
    Overdose symptoms: drop in blood pressure, nausea, vomiting, slowed reflexes, anuria, respiratory depression, coma, cardiac arrest.
    Treatment: rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.

    Interaction with other drugs

  • The simultaneous use of drugs containing phosphates or calcium salts can significantly reduce the absorption of magnesium in the gastrointestinal tract.
  • Magnesium preparations reduce the absorption of tetracycline; it is recommended to separate the administration of these drugs at three-hour intervals.
  • Magnesium weakens the effect of oral thrombolytic agents and reduces the absorption of iron.
  • Vitamin B 6 inhibits the activity of levodopa.
  • special instructions

    Information for patients with diabetes: tablets contain sucrose as an excipient.
    In case of concomitant calcium deficiency, magnesium deficiency should be corrected before taking calcium supplements.
    With frequent use of laxatives, alcohol, intense physical and mental stress, the need for magnesium increases, which can lead to the development of magnesium deficiency in the body.

    Release form

    Film-coated tablets.
    60 or 90 tablets in polymer jars.
    The jars are sealed with a screw-on lid and covered with a protective heat-shrink cap.
    10 tablets per blister pack.
    Each jar or 3 or 5 blister packs is placed in a cardboard pack along with instructions for medical use.

    Storage conditions

    At a temperature not higher than 25 oC.
    Keep out of the reach of children.

    Best before date

    2 years.
    Do not use after expiration date.

    Conditions for dispensing from pharmacies:

    over the counter.

    Manufacturer/organization accepting consumer complaints:

    PJSC Pharmstandard-UfaVITA, 450077, Russia, Ufa, st. Khudayberdina, 28.
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