Magnelis B6 - official instructions for use (in tablet form), indications and contraindications, analogues, reviews. Magnelis B6 - instructions, use, indications, contraindications, action, side effects, analogues, dosage, composition Magnelis B6 sos

The modern and effective remedy “Magnelis B6” can compensate for magnesium deficiency. What does the medicine help with? One of the microelements vital for the full functioning of the human body is magnesium. Numerous negative factors significantly reduce its parameters, for example, severe stressful situations, physical overload, an uncorrected diet, and a similar situation can arise during the period of bearing a baby.

What is the composition and produced form

The manufacturer of the pharmacological agent "Magnelis B6", the instructions for use informs about this, is produced as biconvex round tablets coated with a special coating with a whitish tint. In the pharmacy chain, the product is presented in consumer packaging made of cardboard, 30 pcs. or 50 pcs. or in a polymer bottle of 60 pcs. or 90 pcs.

1 tablet contains the following composition:

  • 470 mg magnesium lactate;
  • 5 mg pyridoxine hydrochloride.

This combination of active components allows you to achieve the desired effect - to fully restore magnesium deficiency.

The auxiliary components are listed:

  • sucrose;
  • povidone;
  • collidon;
  • magnesium stearate;
  • carmellose sodium;
  • talc.

Their main goal is to maintain and enhance the healing properties of the main component.

Produced pharmacological effects

The nutrient magnesium is found in all tissues of the human body, therefore, to compensate for its deficiency, a course of medication “Magnelis B6” is required. Instructions for use (price, reviews, analogues of the drug will be discussed below in the article) indicate that this is the main purpose of the pharmacological agent.

While taking therapeutic doses, metabolic processes are restored and the movement of nerve impulses is regulated, as well as contractions in muscle fibers. In addition, it has antispasmodic, as well as antiplatelet and antiarrhythmic effects.

Active magnesium deficiency in the human body can form due to an uncorrected diet or a significant increase in the need for magnesium molecules. For example, with excessive or intellectual stress, severe and prolonged stress, while pregnant, or uncontrolled use of diuretics.

In addition, Pyrodoxin takes an active part in many metabolic processes, as well as in the regulation of the activity of central nervous system structures. Against this background, the absorption of magnesium from the gastrointestinal tract, as well as its movement into cells, significantly improves.

Tablets "Magnelis B6": what does the medicine help with, what are the indications for use

The instructions indicate that the product will help with hypomagnesemia that has formed due to a number of reasons, whether it is interrelated or not with other deficiency conditions.

Absolute and relative contraindications

Like many other pharmaceutical products, the drug has a list of contraindications:

  • severe renal failure;
  • state of phenylketonuria;
  • individual hyperreaction to the components of the Magnelis medication, from which the tablets can cause side effects;
  • pediatric category of patients up to 5.5-6 years.

If one or a combination of the above contraindications is identified, the specialist will select another remedy to correct hypomagnesemia.

The drug "Magnelis B6": instructions for use

The price and effectiveness of treatment depends on the correctness of the therapy regimen. Based on the instructions included with the medication, for adults the starting dose is 6–8 tablets per day. For children over 6 years old, weighing at least 15–20 kg, a dose of 4–6 tablets, divided into 2–3 doses.

The total duration of the treatment course is determined individually by the specialist, approximately until the parameters of magnesium in the bloodstream are restored. The medication is taken orally; it is recommended to take the tablet with the remaining amount of water.

Side effects

In most cases, the pharmacological agent is well tolerated. The following undesirable effects may rarely occur while taking the medication:

  • gastralgia;
  • dyspeptic disorders - nausea, vomiting, constipation;
  • increased flatulence;
  • allergic conditions.

After discontinuation of the drug, all of the above negative effects disappear on their own.

special instructions

If necessary, the drug can be taken at the time of pregnancy; studies have not revealed any teratogenic effects. However, self-medication is not acceptable - the medication must be prescribed to a pregnant woman by a specialist.

When breastfeeding, it is better to refrain from taking Magnelis B6 tablets, since magnesium has the ability to penetrate into milk. If a person has diabetes, the tablets can provoke a hyperglycemic state because they contain sucrose.

Interaction with other drugs

The absorption of magnesium from the structures of the gastrointestinal tract can be affected by the combination of taking the medication with drugs containing phosphates or calcium salts. In turn, magnesium interferes with the absorption of tetracyclines, oral thrombolytic medications, and iron. The activity of the drug Levodopa is also inhibited.

Analogues of the drug "Magnelis B6"

To compensate for the lack of magnesium in the body, the following structural analogues are intended:

  1. "Asparkam Farmak".
  2. "Additive Magnesium".
  3. "Beauty tabs Elegant with calcium."
  4. "Vitrum forte Osteomag".
  5. "Vitrum Mag."
  6. "Magneroth".
  7. "Magnesium Plus"
  8. "Multi Tabs Active".
  9. "Magne B6".
  10. Magne B6 forte.
  11. Magnelakt.
  12. "Supradin Kids Junior".
  13. "Osteocare solution."
  14. "Pikovit Complex"
  15. "Panangin".

Explains how to take analogues of the drug Magnelis B6, instructions for use.

Price

You can buy Magnelis B6 tablets in Moscow for 320 rubles, and the enhanced form of the drug Forte for 365 rubles. In Kyiv, the price of the medicine is 140 hryvnia, in Kazakhstan – 3603 tenge (90 tablets). In Minsk, pharmacies offer an analogue of Magne B6 for 15–26 bel. rubles

Tired of feeling anxious and irritable? Are you worried about weakness, but your performance leaves much to be desired? Do you have a lump in your throat and a feeling of suffocation? These and other symptoms indicate a lack of magnesium in the body, which the drug Magnelis B6 Forte will help replenish. But remember: there are contraindications for taking it, so you should consult a doctor before using it.

Composition of the drug and its form of production

One tablet contains about 618.43 mg (which is proportional to 100 mg of magnesium) Magnelis B6 Forte. The composition is supplemented with pyridoxine hydrochloride (vitamin B6) in the amount of 10 mg. Additional components in the dragee are ludipress, crospovidone, macrogol 6000. The tablet shell contains hypromellose, titanium dioxide, macrogol-3350 and talc.

The capsule has an oval shape and convexities on both sides, without marks. Covered with a white shell. Tablets of ten pieces are enclosed in an aluminum blister. The package may contain three, six or nine blisters, which corresponds to 30, 60 and 90 tablets. In addition to the medicine, the box contains instructions for use.

Pharmacology of the drug

Magnelis B6 Forte tablets (reviews note that the drug helps cure prolonged depression and strengthens the nerves well) replenish magnesium deficiency. This substance is simply necessary for the human body, because the microelement is involved in the work of cells responsible for metabolism. Involved in stabilizing the transmission of nerve impulses and appears in the contraction of muscle tissue. Half of the total amount of magnesium in the body is found in bone tissue.

The metal is involved in 350 reactions in the human body. It has a beneficial effect on the brain, nervous system, head and heart organ. Strengthens blood vessels. Affects energy and performance. Removes lethargy, depression and fights stress. Copes with limb cramps and prevents their occurrence in the future.

Pyridoxine, also known as vitamin B6, affects many metabolic processes in the body. Positively affects the absorption of magnesium in the gastrointestinal tract. Promotes faster penetration of metal into cells.

If the blood contains 12-17 mg/l of magnesium, then this is a moderate magnesium deficiency. If the amount of trace element in plasma is less than 12 g/l, then the person experiences severe magnesium deficiency. People receive magnesium at the same time as food. Its deficiency occurs due to poor and unhealthy nutrition, during a diet or during pregnancy.

Magnelis B6 Forte is an optimal complex for replenishing magnesium deficiency. Here the magnesium formula is as close as possible to natural. Therefore, the drug is easily absorbed and well tolerated by patients. Vitamin B6 accelerates the process of magnesium absorption by cells.

Clinical studies have proven that the product improves sleep, reduces anxiety signals, and eliminates leg cramps. During pregnancy, it reduces the tone of the uterus and calms the nervous system.

In the gastrointestinal system, the absorption of magnesium salts occurs passively. Here, salt solubility plays a critical role. The degree of absorption is not more than 50%. The drug is mostly excreted by the kidneys.

Indications for use of the medicine

It is advised to take Magnelis B6 Forte tablets only as prescribed by a doctor. Reviews note that the drug helps normalize sleep and eliminates irritability. The prescription for the use of pills is magnesium deficiency. It can be either isolated or associated with other conditions in which excessive irritability and short-term insomnia occur.

It is recommended to take the product for stomach and intestinal cramps. Doctors prescribe the medicine for rapid heartbeat, as well as for increased fatigue of the patient. The drug is used for pain, tingling and spasms in muscle tissue.

They note that Magnelis B6 Forte works effectively for nervousness and irritability, reviews from doctors. Contraindications and side effects must be taken into account before using this product.

When should you not take the pills?

Despite the good results that Magnelis B6 Forte gives for sleep disorders and other diseases, it should not be used if you are hypersensitive to the constituent substances of this drug. A contraindication to the use of tablets is renal failure, which occurs in a serious form when creatinine clearance is less than 30 ml/min. This remedy is not recommended for children under the age of twelve due to the lack of necessary clinical studies.

It is forbidden to take the medicine if you have hereditary galactosemia, lactase deficiency (since the drug contains the component lactose monohydrate), as well as with galactose and glucose malabsorption syndrome. You should not combine levodopa with Magnelis B6 Forte.

The tablets are prescribed with caution for renal failure, which is characterized by moderate severity. There is a possibility of hypermagnesemia.

Magnelis B6 Forte can be used during pregnancy (reviews from pregnant women note that the tablets help remove the tone of the uterus, make the stomach softer, and are very soothing), but only as prescribed by a doctor. The product does not have a negative effect on the formation of the fetus. Magnesium can pass into breast milk, so if you use this drug, you should refrain from breastfeeding for a while.

Magnelis B6 Forte: instructions for use

Capsules are taken orally. They should be swallowed whole, without chewing, with a sufficient amount of liquid.

Adults are prescribed three or four pills a day. They must be divided into 2-3 doses. The product is taken with food. Children over twelve years of age take two or four tablets per day. This number of capsules should be distributed 2-3 times.

Special instructions for the use of tablets

In some cases, Magnelis B6 Forte tablets (reviews note that regular use of the drug eliminates nervousness and muscle cramps) cause side effects. Among them are allergic reactions, which manifest themselves in the form of skin rashes. The drug can cause abdominal pain, diarrhea, gag reflex, flatulence, and nausea.

If taken incorrectly, an overdose of tablets may occur. Often toxic reactions occur with renal failure, since in this case there is a high probability of magnesium poisoning. Symptoms of overdose depend on the content of magnesium in the plasma. It may manifest itself as a decrease in blood pressure, vomiting, depression of the nervous system, and nausea. Abuse of tablets can cause changes in electrocardiogram, coma, anuric syndrome, cardiac arrest, depression and respiratory paralysis.

Overdose is treated with rehydration and forced diuresis. In case of renal failure, hemodialysis is required.

If you used other medications before using Magnelis B6 Forte, you should consult your doctor about the possibility of combining them.

This drug should not be taken by children under twelve years of age. The product contains lactose monohydrate, therefore, it should not be used by patients with hereditary galactosemia, lactase deficiency, as well as patients with galactose and glucose malabsorption syndrome.

If renal failure is observed, which is in a moderate stage of development, then the drug is used with extreme caution, due to the possibility of hypermagnesemia.

If there is a combined deficiency of magnesium and calcium, the deficiency of magnesium must be eliminated first before using products and nutritional supplements that contain calcium.

Pyridoxine, used in high dosages (more than 200 mg) and over a long period, can provoke the occurrence of sensory axonal neuropathy, which will cause reactions such as numbness and failure of proprioceptive sensitivity, tremors of the limbs, and impaired coordination of movements. All these processes are reversible and disappear as soon as vitamin B6 is stopped.

These tablets do not affect the ability to control vehicles and other mechanisms that require excessive concentration.

The product should be stored at a temperature no higher than +25°, out of the reach of children and protected from the sun. The shelf life is two years from the date of manufacture, which is written on the packaging. Do not take the drug after this period.

Analogs

If for certain reasons the drug Magnelis B6 Forte is not suitable, analogues can always replace it. The most popular alternative remedies include:

  • "Magne B6". Fifty tablets cost about 600 rubles. The medicine is manufactured in France.
  • "Magnesium B6". Produced in tablets by Evalar. Sixty tablets cost about 300 rubles.
  • "Asparkam." Contains potassium and magnesium. The price of tablets depends on the manufacturer. Twenty tablets from Pharmstandard cost 50 rubles.
  • "Cormagnesin". Contains magnesium. Available in the form of an injection solution.
  • Magne Express. Country of manufacture: Austria. The cost of 20 sachet packages is 600 rubles.
  • "Magnesium sulfate". Produced in ampoules and in powder form for oral administration. It costs around 30 rubles for ten 5 ml ampoules. Produced in Russia.
  • "Magwit". Manufactured in Belarus. Fifty tablets cost 300 rubles.
  • "Magneroth". Made in Germany. The price of fifty tablets is 300 rubles.

These drugs can replace Magnelis B6 Forte if necessary, but they must be selected by the attending physician.

Cost of tablets

The drug "Magnelis B6 Forte" can be found in every pharmacy. The cost of thirty tablets fluctuates around 350 rubles, and the price of sixty pills is 550 rubles. The product is manufactured in Russia by the Pharmstandard-Tomsk company. The product is dispensed from pharmacies without a doctor's prescription.

Content

If there is a deficiency of magnesium in the body, doctors prescribe Magnelis B6. The medication helps overcome stress and gain emotional balance. Detailed instructions for using Magnelis indicate that the medication is involved in all metabolic processes of the body and has a beneficial effect on the well-being of adults and children. Before starting the course, it is recommended to consult with your doctor.

Composition and release form

Magnelis is a drug recommended for magnesium deficiency in the body.. The medicine is produced in the form of biconvex white tablets, film-coated. The medicine is packaged in contour cells of 10 pieces, 1 cardboard package contains 3 or 5 blisters, or in jars of 60 or 90 pieces. Features of the chemical composition:

Active ingredients of the medicine

Concentration of components for 1 tablet, mg

Active components:

Magnesium lactate dihydrate

pyridoxine hydrochloride

Excipients:

Magnesium stearate

sucrose

carmellose sodium

Kollidon SR (sodium lauryl sulfate – 0.8%, polyvinyl acetate – 80%, povidone – 19%, silicon dioxide – 0.2%)

acacia gum

Shell composition:

sucrose

titanium dioxide

acacia gum

beeswax

Pharmacodynamics and pharmacokinetics

The medicine Magnelis B6 saturates the body with magnesium. This microelement is involved in the process of cellular metabolism, regulates the transmission of nerve impulses by neurons in the brain, and ensures muscle contraction. In addition, it demonstrates antiarrhythmic, antiplatelet, and antispasmodic effects. The second component is vitamin B6 (pyridoxine), regulates the metabolism of the CNS (central nervous system), improves the absorption of magnesium from the stomach and its further distribution in tissues.

The active ingredients of this medication are quickly absorbed from the gastrointestinal tract (gastrointestinal tract), penetrate the bloodstream, and are evenly distributed in the tissues. The breakdown process occurs in the liver. Inactive metabolites are excreted in the urine. According to the instructions, Magnelis tablets are taken with extreme caution if chronic kidney disease is diagnosed.

Why take Magnelis B6

If the patient’s body urgently needs magnesium, Magnelis B6 tablets help ensure balance. Indications for use of the drug are described in the instructions:

  • increased irritability, instability of the central nervous system;
  • cramps of the calf muscles;
  • physical and emotional exhaustion;
  • decreased concentration;
  • increased heart pain;
  • symptoms of tachycardia (rapid heartbeat);
  • chronic insomnia;
  • spasms of the gastrointestinal tract;
  • weakened immune system;
  • muscle pain, impaired tone.

How to take Magnelis B6

The medication is intended to be taken orally as a full course. The tablets must be taken during meals, not chewed, and washed down with plenty of water. Adults are prescribed 6–8 pieces/day. Patients aged 6 years and over weighing 20 kg should take 4-6 tablets/day. The daily dose of the drug is divided into 2-3 doses, the course of treatment is determined individually.

special instructions

Magnelis B6 tablets contain sucrose in their chemical composition, therefore, when treating patients with diabetes mellitus, it is necessary to take this fact into account, individually adjust the daily dosage of hypoglycemic agents or select an analogue. The instructions for use also contain other instructions:

  1. If there is an additional calcium deficiency in the body, the first step is to replenish the magnesium concentration. After this, you can take medications to ensure the balance of the second microelement.
  2. If there is no positive dynamics for 1 month, it is necessary to change the medicine and select an effective analogue.
  3. The drug does not depress the nervous system, therefore, when treated with Magnelis, you can engage in intellectual activities and hazardous types of work, or drive a vehicle.
  4. During treatment, it is advisable to adhere to the diet prescribed by the doctor. It is important to limit alcohol consumption and minimize physical stress on the body.

During pregnancy

Magnelis is recommended for use by women during pregnancy as an effective treatment and reliable prevention of late gestosis. The medicine is necessary to prevent premature birth, when there is a threat of early termination of pregnancy. There are no fetotoxic or teratogenic effects. Only a doctor can prescribe this medicine; unauthorized use by pregnant women is contraindicated.

Magnelis during breastfeeding

During lactation, the medication is contraindicated for use. This is explained by the release of the active ingredients of Magnelis into mother's milk. Negative reactions can develop in a child’s body. If stopping treatment is not advisable, it is necessary to temporarily interrupt breastfeeding and transfer the child to artificial formula.

Magnelis for children

In the form of a drinking solution, Magnelis B6 can be given to children from 6 years of age, tablets - only from 12 years of age. The chemical composition contains components that can harm the health of a small patient. If you violate the instructions from the instructions for use, the baby’s body will develop symptoms of an overdose, represented by nausea, prolonged vomiting, and breathing problems.

For impaired renal and liver function

According to instructions, an absolute contraindication to the use of Magnelis is severe renal failure when creatinine clearance is less than 30 ml/min. If moderate renal impairment is observed, the medication can be used with caution with individual adjustment of daily dosages.

Drug interactions

Since the drug is involved in a complex therapy regimen, when prescribing it, doctors take into account the peculiarities of drug interactions. The instructions for use reflect the following recommendations:

  1. Tetracycline is allowed to be taken at intervals of 3 hours after taking Magnelis, otherwise the absorption of the component is reduced.
  2. Pyridoxine in Magnelis inhibits the activity of Levodopa, so such a pharmaceutical combination is excluded.
  3. Magnelis reduces the activity of oral thrombolytic agents and interferes with the absorption of iron.
  4. Medicines containing calcium salts or phosphates reduce the absorption of magnesium from the gastrointestinal tract.

Side effects

Magnelis is well tolerated by the body. In some clinical cases, side effects may develop that require immediate discontinuation of the drug and selection of an analogue. The instructions for use indicate the patient's complaints:

  • from the digestive system: nausea, flatulence, vomiting, constipation, abdominal pain;
  • from the skin: rashes, urticaria, swelling and itching of the epidermis, hyperemia (redness).

Overdose

The instructions describe cases of magnesium poisoning in patients with severe renal failure. Overdose symptoms:

  • nausea, vomiting;
  • arterial hypotension;
  • respiratory depression;
  • slow reflexes;
  • anuria (lack of urine);
  • short-term cardiac arrest;
  • bradycardia;
  • dizziness, increased fatigue;
  • coma, collapse.

If timely medical care is not provided, doctors do not rule out death. Resuscitation measures require hemodialysis, rehydration (restoration of water balance) and normalization of diuresis. Further treatment is symptomatic and proceeds under medical supervision. Hospitalization of the patient is not excluded.

Contraindications

To exclude the development of hypermagnesemia, treatment with Magnelis is contraindicated in cases of severe renal failure. The instructions indicate other Pathological processes of the body, in the presence of which it is necessary to stop taking magnesium:

  • fructose intolerance;
  • children under 6 years of age;
  • glucose-galactose malabsorption syndrome;
  • sucrase-isomaltase deficiency;
  • phenylketonuria (hereditary disease with impaired amino acid metabolism);
  • lactation period;
  • hypersensitivity of the body to the active ingredients of the drug.

Terms of sale and storage

The medicine is sold in pharmacies without a prescription. The medicine must be stored at temperatures up to 25 degrees, in a dry, dark place out of reach of small children. The date of manufacture of the medicine is indicated on the packaging, the shelf life is 2 years.

Analogs

If the use of this medication does not provide the desired therapeutic effect, or side effects occur, it is recommended to change the treatment regimen. Magnelis analogues:

  1. Magnistad. These are enteric-coated tablets. Adults are recommended to take 2–3 pcs., Children – 1–2 pcs. three times a day. The course of treatment is 30 days. According to the instructions, the drug is prescribed with caution during pregnancy; use during lactation is prohibited.
  2. Magne B6. The use of tablets is recommended for emotional instability, sleep disturbances, pain and spasms of muscles, gastrointestinal tract, and symptoms of tachycardia. Adults are prescribed up to 8 tablets three times a day, children – no more than 6 tablets. The course of treatment is determined individually.
  3. Magne express. This is a dietary supplement in the form of sachets or granules for oral use, necessary for normalizing the functioning of the nervous system and increasing stress resistance. According to the instructions, the daily dose is 1 sachet twice a day for 30 days.
  4. Magnelis B6 Forte. Tablets for oral use. A single dose should be taken with plenty of water. According to the instructions, adults are prescribed 3-4 tablets per day, divided into 2-3 doses, during meals. Children from 3 years old – up to 4 tablets according to the same regimen. The course of treatment is no more than 30 days.

Magnelis price

Average cost of medication per package of 50 pcs. is 300-350 rubles, for 90 pcs. – 400-450 rubles. Buying online is cheaper. The price depends on the city and the reputation of the pharmacy, the number of tablets in the package.

Magnelis B6 is a popular medicine intended to partially or completely replenish the lack of magnesium in the cells and tissue structures of the body. Instructions for use help you understand the rules of administration and eliminate incorrect use so as not to harm your health.

Magnelis B6 is available in the form of white, film-coated tablets for convenient oral administration.

Magnelis B6 is used to replenish the body with magnesium, which is responsible for a number of functions in the body. What effect does the drug have and how to take it.

The drug is available in 3 or 5 blisters of 10 tablets each or in a high-quality polymer jar of 100 tablets.

Compound

Each individual tablet contains 470 mg of pure magnesium lactate and 5 mg of pure vitamin B6.

In addition to the main substances, the drug contains several additional components in small quantities:

  • talc;
  • sucrose;
  • purified kaolin;
  • gelatin and titanium;
  • beeswax;
  • gum.

Pharmacological properties

Magnelis B6 belongs to a group of medications that help restore the required level of magnesium in tissues. The microelement should usually be contained in almost all cellular structures and tissues of the human body; it is very important for normal life.

Processes of general metabolism can never do without the participation of magnesium. It is able to regulate contractile processes in muscle fibers.

A lack of magnesium can occur in case of excessive physical activity, poor diet, frequent stress, during pregnancy and when using certain diuretic drugs.

Vitamin B6 is also very important for the normal functioning of metabolic processes. It promotes better absorption of the microelement from the stomach, as a result of which it is distributed more quickly throughout the cells. Magnelis B6 has antispasmodic and antiarrhythmic effects. The absorption of the substance is 50%. Usually excreted naturally in urine.

The drug ensures the following important processes in the body:


How is it absorbed by the body?

The absorption of magnesium by cellular structures immediately after taking one tablet is about 50%. These medications are usually excreted in the urine. With 70% of the magnesium found in plasma after filtration in the kidneys, the level of reabsorption of the trace element directly into the renal tubules itself is usually approximately 95%.

Indications for use

Magnelis B6 must be taken if there is a clearly established acute deficiency of magnesium in the body. This condition may be independent or associated with pathological diseases or microelement deficiency for other reasons.

It usually manifests itself with the following symptoms:


These symptoms especially manifest themselves during the period of bearing and feeding the baby. Using the drug will help avoid the development of such symptoms. Magnelis B6 helps saturate cells with magnesium, resulting in decreased muscle tone.

Contraindications

Although this drug is very beneficial, it should be taken with some caution. Therefore, it is not recommended to self-medicate.

This medicine has a number of serious contraindications:


The medication is prescribed with extreme caution in cases of mild renal failure. Excessive accumulation of magnesium often leads to hypermagnesemia. You should not take this drug if you have glucose intolerance or diabetes. Magnelis B6 is not used for children under 6 years of age.

For impaired renal function

Severe chronic renal failure is considered one of the first prohibitions on the use of the drug. If the disturbances in kidney function are moderate, then take the medication strictly following the doctor’s instructions.

Directions for use and dosage regimen

Magnelis B6 can be used by both adults and children over 6 years old. Reception is not associated with meals. It is important to know! The exact dosage and duration of treatment is prescribed by the doctor; it will depend on the initial level of magnesium ions in the tissue and cellular structures of the body.

For children over 6 years of age whose weight is more than 20 kg, 1 tablet 3 times a day is usually prescribed. For adults and children over 12 years of age, 2 tablets 3 times a day are usually prescribed. You need to take the medication with plenty of boiled water. If necessary, the tablets are crushed and dissolved in water.

Therapy is considered complete when the concentration of the microelement in the blood reaches normal values.

The drug is prescribed for prophylactic purposes and to reduce the load on the cardiovascular system. Therapy in this case lasts 1 month.

Use during pregnancy and breastfeeding

Instructions for use of Magnelis B6 indicate that the medication does not have a teratogenic or embryotoxic effect. Therefore, it is often prescribed to women regardless of the trimester of pregnancy. Magnesium is needed to prevent possible complications during fetal formation, as well as to prevent late gestosis.

According to reviews of gynecologists and patients who took the medication, Magnelis B6 has only a positive effect on the body. But only the obstetrician leading the pregnancy should prescribe the drug. The dose and duration of treatment are determined based on the characteristics of the woman’s body and the degree of magnesium deficiency.

While the feasibility of choosing a medication can be discussed with a doctor while carrying a baby, taking pills during breastfeeding is strictly prohibited. Magnesium itself and some other components of the drug can quickly penetrate directly into breast milk. As a result, they enter directly into the baby’s body.

This can cause many negative reactions. In cases where such drug therapy cannot be canceled due to the low magnesium content in the mother’s blood, it is recommended to temporarily suspend breastfeeding while taking medications. Self-administration of medications during pregnancy is strictly prohibited.

How to use for children

Instructions for use of Magnelis B6 indicate that age under 6 years is an absolute contraindication to its use. Magnelis B6 Forte should not be taken by children under 12 years of age. This is due to the presence of active substances in the product that can be harmful to the child’s health.

If an overdose occurs, children develop respiratory failure and vomiting. Children under 6 years of age are recommended to be given magnesium preparations only when absolutely necessary in the form of solutions, strictly monitoring compliance with the dosage.

Side effects

The drug is usually well tolerated by patients. Undesirable effects can only occur in people with increased individual sensitivity to certain components of the drug.

Side effects include:

  • allergic skin rashes;
  • hives;
  • severe abdominal pain and flatulence;
  • constipation;
  • nausea and in some cases severe vomiting.

If there are any signs of a negative reaction of the body to taking the drug, you need to stop taking it.

Overdose

If the kidneys are functioning normally, then there should be no signs of a severe overdose. In the case of certain problems with the normal functioning of the kidneys, especially if the medicine is taken in large doses, signs indicating magnesium toxicity may develop.

Among them:


In the most severe cases, if all necessary resuscitation measures are not provided in time, death may occur.

Treatment of severe overdose of magnesium preparations, especially in people with pathologies of kidney function, should consist of urgent hemodialysis and rehydration procedures. It is very important to restore diuresis. The patient must remain under the strict supervision of doctors for some time.

Special conditions

The instructions for use contain special instructions that should be given close attention.

These include:

  • Diabetes mellitus requires care, since the drug contains a fairly large amount of sucrose.
  • Calcium deficiency - first of all, with this diagnosis, it is necessary to normalize the magnesium content, and then begin treatment for calcium deficiency in the human body.
  • Particular care must be taken when driving vehicles, since there is no exact information about whether the medication affects the concentration of general attention and the speed of the necessary brain reactions.
  • If after a month of therapy there is no result, then you should stop taking this medicine.

Before using the medicine, you need to carefully read the instructions so as not to miss important points when you need to use this medicine very carefully.

Interaction of the drug with other drugs

The medicine is not recommended to be combined with some specific medications that contain phosphates and calcium compounds, since the absorption of pure magnesium directly from the gastrointestinal tract itself is significantly reduced.

If Magnelis B6 is used simultaneously with Tetracycline, then the therapeutic effect of the latter will no longer be sufficient. If there is an urgent need for just such a drug interaction, it is advisable to maintain a break between medications. They should be taken no earlier than 3 hours later.

Taking magnesium interferes with the normal absorption of many iron preparations used in the treatment of anemic conditions. Since Magnelis B6 contains Pyridoxine, it greatly inhibits the possible medicinal effect of Levodopa.

Interaction with alcohol

The effectiveness of the drug when drinking alcohol during use is significantly reduced, since almost all magnesium is washed out of cells and tissues without remaining in the cellular structures of the body. Taking Magnelis B6 in combination with a small amount of alcohol will not have serious consequences.

Analogs

There are several similar medications that have similar composition and active substances. There are also medications that give almost the same therapeutic effect, but the composition of all of them is completely different.

Main analogues:

  • Magnistad;
  • Magnelis B6 Forte;
  • Magne B6;
  • Magnesium plus B6;
  • Magne Express;
  • Magwit;
  • Magnerot;
  • Magnicum.

Before replacing Magnelis B6 with one of these analogues, you should consult with a specialist about the required dosage of the medicine.

What is better Magne B6 or Magnelis B6?

Both medications are intended specifically to eliminate persistent magnesium deficiency in a healthy body. They have the same indications and even prohibitions for use. The main difference is the number of active components. Magne B6 contains twice as much vitamin B and magnesium itself as Magnelis B6. There is also a slight difference in the composition of additional components.

A big difference is manifested in prices, since Magne B6 is a French drug, and Magnelis B6 is domestic, the price of the products differs almost 2 times.

Magnelis B6 or Magnerot?

The only difference between Magnelis B6 and Magnerot is that Magnerot does not contain vitamin B6. It contains only magnesium. Otherwise, the drugs are considered complete analogues.

When treating heart disease, disorders of neurovegetative reactions and high blood pressure, doctors recommend choosing Magnerot. It has a more pronounced effect on the heart and blood vessels.

Panangin or Magnelis B6?

The main difference between these drugs is that Panangin, in addition to magnesium itself, also contains potassium, which helps to normalize the functional activity of cells so that they receive more useful substances. The medicine is available not only in tablets, but also in the form of a solution for intravenous use.

Storage conditions and shelf life

The medication can be purchased at pharmacies without a doctor's prescription. The drug should be stored in a dark place at room temperature. If you follow the rules for storing the drug, the shelf life is 3 years from the date of manufacture.

Price and terms of sale

The cost of the drug can vary, starting from 250. The drug is indispensable for normalizing the level of magnesium in tissues. Instructions for use of the drug Magnelis B6 describe the features of using the drug for children and adults, for women during pregnancy and breastfeeding.

Before use, you should familiarize yourself with the precautions and adverse reactions in case of overdose.

Magnelis B6 should be prescribed by the attending physician, who will determine the dosage and duration of the course of therapy based on the results of laboratory tests and the individual characteristics of each patient’s body.

Article format: Lozinsky Oleg

Video about Magnelis B6

Review of the drug, composition and comparison with the analogue:

Dosage form:  film-coated tablets Compound:

For one tablet

Active ingredients

Magnesium lactate dihydrate - 470 mg

in terms of magnesium (Mg 2+) - 48 mg

Pyridoxine hydrochloride - 5 mg

Excipients: sucrose (white sugar) - 27.4 mg, kaolin - 41.0 mg, acacia gum (gum arabic) - 25.0 mg, Kollidon ® SR [polyvinyl acetate 80%, povidone (K 30) 19%, sodium lauryl sulfate 0.8%, silicon dioxide 0.2%] - 34.0 mg, magnesium stearate - 6.8 mg, carmellose sodium - 34.0 mg, talc -6.8 mg.

Shell composition: sucrose (white sugar) - 166.7 mg, kaolin - 54.0 mg, gelatin - 0.9 mg, acacia gum (gum arabic) - 4.0 mg, beeswax - 0.4 mg, titanium dioxide - 9, 0 mg, talc - 15.0 mg.

Description:

Round biconvex tablets, coated in white with a grayish tint. On a cross section, the rough core is white with inclusions ranging from white with a creamy tint to light yellow.

Pharmacotherapeutic group: Magnesium preparation ATC:  
  • Magnesium preparations
  • Pharmacodynamics:

    Replenishes magnesium deficiency.

    Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells. Participates in most metabolic reactions, in the regulation of the transmission of nerve impulses and in muscle contraction, and has antispasmodic, antiarrhythmic and antiplatelet effects.

    The body receives magnesium through food. A lack of magnesium in the body can occur when the diet is disrupted or when the need for magnesium increases (with increased physical and mental stress, stress, pregnancy, use of diuretics).

    Pyridoxine (vitamin B 6) is involved in many metabolic processes and in the regulation of nervous system metabolism. Vitamin B 6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.

    From 12 to 17 mg/l (0.5-07 mmol/l) indicates moderate magnesium deficiency;

    Below 12 mg/L (0.5 mmol/L) indicates severe magnesium deficiency.

    Pharmacokinetics:

    Absorption of magnesium in the gastrointestinal tract is 50% of the dose taken orally. It is excreted primarily through the kidneys. In the kidneys, after glomerular filtration of 70% of the magnesium present in the plasma, it is reabsorbed by the renal tubules in a proportion of 95-97%.

    Indications:

    Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as: increased irritability; minor sleep disorders; gastrointestinal cramps; cardiopalmus; increased fatigue; pain and muscle spasms, tingling sensation in the muscles.

    Contraindications:

    Hypersensitivity to the components of the drug, severe renal failure (creatinine clearance less than 30 ml/min), sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

    Children's age up to 6 years.

    Carefully:

    In case of moderate renal failure, as there is a risk of developing hypermagnesemia.

    Pregnancy and lactation:

    Pregnancy

    Clinical experience has not revealed fetotoxic or fetal malformation effects. Magnelis® B 6 can be used during pregnancy only as prescribed by a doctor.

    Breastfeeding period

    Magnesium passes into breast milk.

    The use of the drug should be avoided during breastfeeding.

    Directions for use and dosage:

    Before taking the drug, you should consult your doctor.

    Children over 6 years old (body weight more than 20 kg) 4-6 tablets per day.

    The daily dose should be divided into 2-3 doses, taken during meals with a glass of water.

    Treatment should be stopped after normalization of magnesium concentration in the blood.

    Side effects:

    From the gastrointestinal tract: abdominal pain, constipation, nausea, vomiting, flatulence.

    Allergic reactions: V Allergic reactions to the components of the drug are possible.

    Overdose:

    With normal renal function, oral magnesium intake does not cause toxic reactions. Magnesium poisoning can develop due to kidney failure. Toxic effects mainly depend on serum magnesium levels.

    Overdose symptoms: drop in blood pressure, nausea, vomiting, slowed reflexes, anuria, respiratory depression, coma, cardiac arrest.

    Treatment: rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.

    Interaction:

    The simultaneous use of drugs containing phosphates or calcium salts can significantly reduce the absorption of magnesium in the gastrointestinal tract.

    Magnesium preparations reduce the absorption of tetracycline; it is recommended to separate the administration of these drugs at three-hour intervals.

    Magnesium weakens the effect of oral thrombolytic agents and reduces the absorption of iron.

    Vitamin B 6 inhibits the activity of levodopa.

    Special instructions:

    Information for patients with diabetes: tablets contain sucrose as an excipient.

    In case of concomitant calcium deficiency, magnesium deficiency should be corrected before taking calcium supplements.

    With frequent use of laxatives, alcohol, intense physical and mental stress, the need for magnesium increases, which can lead to To development of magnesium deficiency in the body.

    Impact on the ability to drive vehicles. Wed and fur.:

    The drug does not have a negative effect on driving vehicles and performing potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

    Release form/dosage:

    Film-coated tablets.

    Package:

    60 or 90 tablets in polymer jars made of low-density polyethylene.

    The jars are sealed with screw-on lids made of high-density polyethylene or low-density polyethylene.

    Each can is covered with a polyvinyl chloride heat-shrink tube. 10 tablets per blister pack.

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