Eye ointment Galazolin. Galazolin ® nasal drops. Terms of dispensing from pharmacies

Galazolin is a nasal vasoconstrictor used topically in ENT practice. The active substance is Xylometazoline.

Alpha adrenostimulator, narrows the blood vessels of the nasal mucosa, eliminating swelling and hyperemia of the mucous membrane. Facilitates nasal breathing in rhinitis.

The drug is prescribed for instillation into the nose, has a vasoconstrictive effect, reduces swelling, reduces hyperemia and reduces exudation.

The action of Galazolin nose drops occurs after a few minutes and lasts for several hours.

The most common form of release are nasal drops with different dosages of the active substance. They also produce nasal gel, metered and non-metered spray and Galazolin aerosol.

Drops in the nose are addictive, so when the runny nose decreases, you should stop using them. The optimal course of therapy is 3-5 days, during which the drug can be used no more than 3 times a day.

Indications for use

What helps Galazolin? According to the instructions, nose drops are prescribed in the following cases:

• Acute rhinitis of viral or bacterial origin;
• allergic rhinitis;
• Acute sinusitis;
• Chronic sinusitis in the acute phase;
• Pollinosis;
• Otitis media (in order to reduce swelling of the mucous membrane of the nasopharynx and restore the patency of the Eustachian tube).

Instructions for use Galazolin, dosage drops

The use of the drug depends on the form of release and dosage of the active substance. Recommended dosage instructions for use:

• Drops of Galazolin 0.1% for adults and children over 12 years old - from 2 to 3 drops in each nasal passage. Instillation is carried out every 8-10 hours.
• Children's Galazolin (0.5%) in the form of drops - 1 drop for children from 4 months to two years, 2-3 drops for children from 2 to 12 years (every 8-10 hours).
• Nasal gel 0.05% for children aged 3-12 years - 1 pump in each nasal passage every 8-10 hours.
• Nasal gel 0.1% for adults and children over the age of 12 - 1 pump in each nasal passage every 8-10 hours.

The course of treatment is 3-5 days and in any case should not exceed 10 days. Do not use the drug more than 3 times a day.

special instructions

Long-term use and overdose should be avoided (weakening of action and the likelihood of mucosal atrophy and reactive hyperemia with drug-induced rhinitis).

It should not be taken simultaneously with MAO inhibitors and within two weeks from the last dose of these drugs.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Galazolin drops:

• Irritation and / or dryness of the mucous membrane of the nasopharynx;
• Burning and paresthesia of the nasal mucosa;
• Sneeze;
• Hypersecretion of the mucous membrane of the nasal cavity;
• swelling of the nasal mucosa;
• palpitations;
• Tachycardia;
• Arrhythmia;
• Increased blood pressure;
• Headache;
• Vomit;
• Insomnia;
• visual impairment;
• Depression.

Contraindications

Galazolin is contraindicated in the following cases:

• atrophic rhinitis;
• Angle-closure glaucoma;
• Increased intracranial pressure;
• Severe atherosclerosis;
• Hyperthyroidism;
• Arterial hypertension;
• Diabetes;
• Tachycardia;
• Individual sensitivity to the active substance or other components of the drug;
• Pheochromocytoma.

According to strict indications, it is possible to use the drug during pregnancy and lactation.

Overdose

Significant overdose or accidental ingestion, especially in children, may cause sedation, visual disturbances, headache, irritability, heart rhythm disturbances, and insomnia.

Long-term use may lead to the development of secondary drug-resistant rhinitis resistant to therapy.

Treatment is symptomatic.

Galazolin analogues, price in pharmacies

If necessary, Galazolin drops can be replaced with an analogue for the active substance - these are drugs:

1. (from 12.00 rubles),
2. Rhinorus (from 16.00 rubles),

Release form

Compound

Active ingredient: Xylometazoline (Xylometazoline) Active ingredient concentration (%): 0.05

Pharmacological effect

Vasoconstrictor drug for local use in ENT practice. alpha-agonist from the group of imidazole derivatives. at low concentrations, it acts on α2-adrenergic receptors, at high concentrations it has an effect on α1-adrenergic receptors. When applied topically, it causes constriction of blood vessels, which leads to a decrease in edema and hyperemia of the mucous membranes of the nasopharynx, reduces the amount of discharge from the nose, and facilitates nasal breathing with rhinitis. the effect of the drug begins after 5-10 minutes and lasts for 5-6 hours when used in the form of nasal drops and for 10 hours when used in the form of a nasal gel.

Pharmacokinetics

Indications

Acute rhinitis of viral or bacterial origin; - allergic rhinitis; - acute sinusitis; - chronic sinusitis in the acute phase; - hay fever; - otitis media (in order to reduce swelling of the nasopharyngeal mucosa and restore patency of the Eustachian tube).

Contraindications

Hypersensitivity to the components of the drug; - atrophic rhinitis; - angle-closure glaucoma; - arterial hypertension; - severe atherosclerosis; - tachycardia; - hyperthyroidism (for nasal drops); - surgical intervention on the meninges (in history); - simultaneous use of MAO inhibitors and a period of 14 days after the end of their use; - simultaneous administration of tricyclic antidepressants; - pregnancy; - children under 6 years of age (for 0.1% nasal drops) and up to 2 years (for 0.05% nasal drops)

Precautionary measures

The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C.

Use during pregnancy and lactation

Contraindicated in pregnancy. Data on the allocation of xylometazoline with breast milk is not available. It is necessary to prescribe the drug with caution to women during lactation (breastfeeding).

Dosage and administration

Side effects

Local reactions: with frequent and / or prolonged use - irritation and / or dryness of the mucous membrane of the nasopharynx, burning and paresthesia of the mucous membrane of the nasal cavity, sneezing, hypersecretion of the mucous membrane of the nasal cavity; rarely - swelling of the nasal mucosa. Systemic reactions: rarely - palpitations, tachycardia, palpitations, arrhythmias, increased blood pressure (especially in patients with diseases of the cardiovascular system), headache, nausea, vomiting, insomnia, weakness, fatigue, drowsiness, blurred vision, allergic reactions (suffocation, vasomotor edema); with prolonged use and / or when used in high doses - depression, drug-induced rhinitis.

Overdose

There have been no cases of overdose in adults. In case of using too large a dose or improper use, swallowing of drops and absorption of the active substance from the gastrointestinal tract may occur. It occurs mainly in children. In this case, a pronounced sedative effect is observed. Symptoms: if the drug is accidentally swallowed (more often in children), tachycardia, arrhythmia, increased blood pressure, drowsiness, confusion, respiratory depression or irregular breathing are noted. Treatment: symptomatic therapy is carried out.

Interaction with other drugs

Incompatible with MAO inhibitors and tricyclic antidepressants. With the simultaneous use of xylometazoline with other sympathomimetics (for example, ephedrine, pseudoephedrine), the action is potentiated. This combination should be used with caution.

special instructions

Before use, it is necessary to clear the nasal passages. Galazolin, like other sympathomimetics, should be used with extreme caution in patients with hypersensitivity to adrenomimetics, manifested by insomnia, dizziness, tremor, heart rhythm disturbance and increased blood pressure. The drug should not be used in patients with chronic or vasomotor rhinitis because they tend to use the drug for more than 5 days. Prolonged use of the drug (more than 2 weeks) can lead to secondary vasodilation and subsequently to secondary drug-induced rhinitis. The cause of this disease is the inhibition of the release of norepinephrine from nerve endings by excitation of presynaptic α2 receptors. The recommended doses should not be exceeded, especially in children and elderly patients. The drug contains benzalkonium chloride, therefore it can cause irritation of the nasal mucosa. Influence on the ability to drive vehicles and control of mechanisms The drug does not affect the ability to drive vehicles and maintain moving mechanisms if used at the recommended dose and for a short time. With prolonged use or use in high doses, undesirable effects on the cardiovascular system and central nervous system may occur. In the event of the development of side effects, the drug may affect the ability to drive vehicles and mechanisms.

It is simply impossible to cure a runny nose without vasoconstrictor drugs. Such an effective drug as Galazolin helps in this. It is actively involved in the treatment of rhinitis in children and adults. During the treatment, the question arises whether it is possible for children, the answer is unequivocal, since it is possible to achieve a stable result and eliminate nasal congestion for a long time.

What to do. when the sore in the nose does not go away for a long time, indicated in this

Effect

The presented drug has a pronounced vasoconstrictor effect. It is enough to wait 2 minutes after use and achieve the desired result. Galazolin is characterized by a mild effect on the nasal mucosa, as a result of which local irritation does not occur. During treatment, if all dosages are observed, it is possible to protect yourself from side effects. As for the shortcomings, they include a short time of use. Otherwise, habituation begins to arise. It is allowed to use the drug for 4 days, but not longer.

The positive effect of the drug is based on the chemical properties of the main component. It belongs to the group of alpha-agonists. It is able to have a therapeutic effect, which is involved in the regulation of muscle tone of the vascular wall of the capillaries. Since the drug is used locally, the drug component is absorbed by the cells of the mucosa.

The result of therapy with the use of Galazolin is the achievement of the following effect:

• penetration into the muscle cells of the vascular wall contributes to the achievement of a short-term spasm;
• a sharp decrease in the capacity of the vessel wall leads to permeability and blood effusion;
• elimination of puffiness and hyperemia of tissues;
• elimination of excess production of mucous secretion.

What to do when snot flows from the nose like water is indicated in this

The resulting therapeutic effect lasts for 4-4.5 hours. After that, you need to reuse the medication. If you strictly follow all the rules, then in a short period of time it is possible to return the full conductivity of the nasal airways and remove the stuffiness of the Eustachian tube. In the hearing aid, it is possible to overcome excess band pressure, the patient can forget about dizziness and pain in the head.

If you take the drug for a long time, then addiction can form. The nose will breathe freely, but on the condition that you have to constantly drip it in drops. With this development of events, all conditions are created for the development of drug-induced rhinitis, and such a disease is very difficult to cure.

The medicine has a negative effect on such concomitant ailments as atherosclerosis, diabetes mellitus, hyperthyroidism, hypertension, tachycardia.

You can not use drops in combination with monoamine oxidase inhibitors and for 2 weeks after their cancellation. This statement is also true for tetracyclic antidepressants.

As indicated in the instructions, during the bearing of a child, it is allowed to use drops in the dosage that is reserved for children. In this case, be sure to consult a specialist, otherwise there may be a risk of oxygen starvation of the baby.

Use the drug in the form of drops for children from 3 to 6 years old, 1-2 drops in each nostril 2 times a day. For older children and adults, use the drug at a dosage of 1-2 drops 3 times a day.

What to do when, you can find out by reading the article.

Price

As for the cost, you can buy the drug for 29 rubles. This is a very low price, although the effectiveness of the drug is very high. for sale
Galazolin without a prescription.

Galazolin refers to a-adrenergic agonists. According to the chemical structure, it is a derivative of imidazoline. Under the action of Galazolin, a narrowing of arterial vessels occurs. As a result, the swelling of the mucous membrane of the nasal passages decreases, the amount of discharge decreases. The relief of edema helps to restore the patency of the nasal passages, the Eustachian tube and sinus openings. After applying Galazolin, the effect develops after 5-10 minutes. The duration of the vasoconstrictor effect is 8-12 hours. If the dosage is observed, clinically significant absorption of the drug, as a rule, is not observed.

Indications for use

Mode of application

Side effects

Contraindications

Pregnancy

Interaction with other drugs

Overdose

Storage conditions

Release form

Compound

Additionally

"Galazolin" is a drug based on xylometazoline. It is available in nasal drops and nasal gel dosage forms. The following is an instruction for the use of drops in the nose "Galazolin".

Mechanism of action

Drops "Galazolin" have a fairly pronounced local vasoconstrictor effect. When instilled into the nose, the active substance - xylometazoline acts on adrenoreceptors in the walls of small vessels of the mucous membrane. The interaction of the drug with these receptors leads to a contraction of the smallest muscles of the vascular wall. In this case, the lumen of the vessels decreases. Reduced blood flow to the mucous membrane and its swelling. As a result, the gaps of the nasal passages expand, free breathing is restored.

Drops "Galazolin" do not affect the feeling of itching or burning. They slightly reduce the production of mucus.

A tangible effect in the form of restoring free breathing through the nose occurs 3-5 minutes after taking the drops and lasts up to 6 hours. Residual vasospasm persists up to 12 hours; reuse of drops during this period is not recommended.

Composition and form of release

Drops "Galazolin" are available in two dosages - 0.05% (lower) and 0.1% (higher concentration). They can be produced in vials or in dropper bottles, whichever is more convenient.

Indications for use

Drops "Galazolin" are used for allergic, viral, bacterial acute rhinitis, as well as for exacerbation of chronic rhinitis. They are also prescribed for nasopharyngitis and otitis media without the formation of purulent discharge.

"Galazolin" can be used for acute and chronic sinusitis, frontal sinusitis and other sinusitis.

Contraindications

"Galazolin" can not be used for individual intolerance to xylometazoline.

It is not prescribed for atrophic rhinitis.

"Galazolin" should not be used for concomitant diseases such as severe atherosclerosis (including coronary heart disease), diabetes mellitus, hyperthyroidism (increased thyroid function), hypertension, a tendency to tachycardia (rapid heartbeat), pheochromocytoma (tumor of the adrenal glands, producing adrenaline).

Drops are forbidden to be used simultaneously with monoamine oxidase inhibitors, as well as within 2 weeks after their cancellation. This indication is also true for tri- and tetracyclic antidepressants.

The instruction states that during pregnancy it is allowed to use xylometazoline drops in a “children's” dosage as prescribed by a doctor, taking into account the possible risk of oxygen starvation of the fetus.

During breastfeeding, the use of this medicine is possible with caution.

Drops "Galazolin" is not prescribed for children under 2 years (0.05%) or up to 6 years (0.1%).

Side effects

Basically, "Galazolin" causes local side effects associated with irritation and drying of the mucous membrane - itching in the nose, burning, sneezing, irritation, dryness. There may be a tendency to nosebleeds.

With prolonged use of Galazolin, tachyphylaxis, or addiction, occurs quite quickly. In this case, the nose breathes freely only with constant instillation of the drug. This mode of application leads to the development of drug-induced rhinitis, which is very difficult to treat.

The risk of absorption of the drug into the blood with the development of systemic effects is small. Nevertheless, palpitations, nervous excitability and insomnia, increased blood and intraocular pressure, and nausea are possible. These phenomena are caused by the action of xylometazoline on small vessels throughout the body.

Dosage

Drops of 0.1% are prescribed for children 6 years of age and older and adults, 2-3 drops in each nasal passage up to 3 times a day.

Drops of 0.05% can be used in children from 2 to 6 years old, 1-2 drops up to 2 times a day in each nasal passage.

The duration of taking drops should not exceed 5 days.

Do not forget that the packaging with drops should be individual for each sick family member.

Overdose

The development of an overdose is more likely in children. It can be manifested by rapid heartbeat, increased blood pressure, impaired consciousness. Treatment of these conditions is symptomatic.

Storage conditions

The instruction recommends storing Galazolin drops in a dark place at a temperature not exceeding 25 ° C, but not in the refrigerator. The shelf life of a closed vial is 4 years. After opening, it is advisable to use the drug within a year.