Lisobact instructions. Lizobakt is an effective and safe local antiseptic for children and nursing mothers. Which is better: "Laripront" or "Lizobakt"

Lyzobakt is a local antiseptic for use in otorhinolaryngological practice for erosive and ulcerative lesions of the oral mucosa, incl. for the treatment of recurrent aphthous stomatitis.

It has a combined effect: antimicrobial, antiviral, anti-inflammatory, analgesic, reparative, anti-relapse, immunostimulating.

Unlike the potent antibiotics of the latest generation, Lizobakt cannot boast of an instant antimicrobial effect, but compares favorably with this group of drugs with the almost complete absence of contraindications: it can be taken by pregnant women and children.

Clinical and pharmacological group

Antiseptic for local use in ENT practice and dentistry.

Terms of dispensing from pharmacies

Released without a doctor's prescription.

Prices

How much does Lizobakt cost? The average price in pharmacies is at the level of 270 rubles.

Release form and composition

Lizobact is available in the form of lozenges: white, yellowish-white or pale cream, round, with a risk on one side (10 tablets in a PVC / aluminum foil blister, 1 or 3 blisters in a cardboard box).

Active substances in 1 tablet:

  • Lysozyme hydrochloride - 20 mg;
  • Pyridoxine hydrochloride - 10 mg.

Additional components: magnesium stearate, gum tragacanth, lactose monohydrate, vanillin, sodium saccharinate.

Pharmacological effect

Analgesic, antiseptic, anti-inflammatory local. Antiseptic for local use in ENT practice and dentistry. Lysozyme is an enzyme of a protein nature (mucolytic enzyme mucopeptide-N-acetylmuramyl hydrolase) and is used as an antiseptic (causes lysis of the cell membrane of gram-positive and gram-negative bacteria and fungi), it also has antiviral activity.

Pyridoxine promotes the regeneration of the oral mucosa and has an anti-aphthous effect.

Indications for use

According to the instructions, Lizobakt is prescribed for the treatment of diseases of the mucous membrane of the gums, oral cavity and larynx of an infectious-inflammatory nature, namely:

  1. aphthous ulceration;
  2. Erosion of the oral mucosa of any etiology;
  3. Catarrhal phenomena of the upper respiratory tract;
  4. Herpetic lesions (usually as part of complex treatment).

Contraindications

According to the instructions and reviews, the drug is well tolerated, acts quickly enough, helps to cope with a large number of diseases affecting the mucous membrane of the throat and oral cavity.

However, like any other synthetic remedy, it has its own contraindications, including:

  • individual intolerance to the composition;
  • age up to 3 years;
  • lactose intolerance.

With caution, you need to take the drug in the early stages of pregnancy, with chronic diseases of the liver, kidneys.

Use during pregnancy and lactation

It is allowed to use Lizobakt for the treatment of pregnant women, as well as nursing mothers. The drug, which does not contain any substances dangerous to either the mother or the child, can be used to treat the throat and mouth in women at almost any stage of pregnancy. The only limitation is, as for other patients, individual intolerance to the components of the drug.

Meanwhile, during the first trimester, when the fetus is forming, women are not recommended to take any medications. If the medicine was nevertheless prescribed (as the best option for pregnant women among all analogues), the dosage remains standard for an adult patient. The same applies to nursing mothers - the dose is normal, and therapy with Lysobact does not require, unlike other anti-inflammatory drugs, transferring the baby to artificial nutrition.

Dosage and method of application

The instructions for use indicate: the tablets of the drug Lizobakt should be slowly absorbed without chewing, holding the melted mass of the tablet in the oral cavity for as long as possible, until completely dissolved.

  • Children aged 3-7 years - 1 tab. 3 times a day, children aged 7-12 years - 1 tab. 4 times a day.
  • Adults and children over 12 years of age are prescribed 2 tablets. 3-4 times a day.

The course of treatment is 8 days.

Side effects

The drug almost never causes side effects. In some cases, there were local allergic reactions caused by individual intolerance to one of the active components of the drug.

These phenomena disappear after refusing to take the medicine.

Overdose

There are no cases of drug overdose in the instructions, but in order to avoid adverse reactions, you must strictly adhere to the dose of the drug. In very rare cases, numbness in the mouth may occur, but this symptom will pass within a few minutes.

special instructions

In the event of an allergic reaction, the use of the drug should be discontinued. In such cases, the patient should consult a doctor.

drug interaction

When used together, Lizobakt enhances the effect of antibiotics, incl. penicillin, chloramphenicol, nitrofurantoin, enhances the action of diuretics, weakens the activity of levodopa.

Isoniazid, penicillamine, pyrazinamide, immunosuppressants, estrogens, and oral contraceptives may increase the need for pyridoxine (pyridoxine antagonism or increased renal excretion).

Lysobact is an antiseptic drug that has a local effect. Scope - dentistry and ENT practice. The active substance lysozyme (an enzyme of a protein nature), which is part of the composition, is an effective antiseptic and regulator of local immunity, and pyridoxine protects the oral mucosa without reducing the action of lysozyme. The drug suppresses bacteria in viral and infectious diseases. The drug is rapidly absorbed from the gastrointestinal tract, the active form is stored in the liver, muscles and other tissues of the body. Lizobakt not only does not interfere, but even enhances the action of antibiotics.

1. Pharmacological action

Drug group: Antimicrobial drug of natural origin. Therapeutic effects of Lizobakt:

  • Antiseptic action;
  • Increased local immunity;
  • Anti-inflammatory action;
  • Protection of the oral cavity from the action of pathogenic factors;
  • Prevention of candidal lesions of the oral cavity.
Pharmacokinetics: The therapeutic concentration of Lysobact is reached after an hour and a half. Lizobakt is able to penetrate into breast milk and through the placental barrier.

2. indications for use

  • chronic;
  • relief of the condition of patients after tonsillectomy;
  • acute;
  • sore throats;
  • erosions of the oral cavity.

3. How to use

  • 3-7 years: one tablet of the drug three times a day;
  • 7-12 years: one tablet of the drug four times a day;
  • older than seven years and adult patients: two tablets of the drug up to four times a day;
  • recommended duration of Lizobakt application: eight days.
Application Features: If necessary, or as directed by the attending physician, the use of Lyzobact can be continued.

4. Side effects

Hypersensitivity skin reactions to Lysobact.

5. Contraindications

  • Hypersensitivity to Lizobakt or its components;
  • Individual intolerance to Lizobakt or its components.

6. During pregnancy and lactation

Pregnant women can take Lyzobact at the direction of a specialist. Breastfeeding mothers can take Lyzobact as directed by a specialist.

7. Interaction with other drugs

Simultaneous use of Lizobakt with:

  • Penicillamine, drugs from the group of immunosuppressants, Hydralazine or contraceptive drugs containing female sex hormones leads to an acceleration of the excretion of Lysobact;
  • Levodopa preparations leads to a decrease in their medicinal effect.

8. Overdose

Symptoms:

  • Various hypersensitivity reactions to Lysobact;
  • Musculoskeletal system: muscular tissue dystrophy.
Specific antidote: does not exist. Treatment of overdose with Lysobact: symptomatic. Hemodialysis: does not lead to an effective result.

9. Release form

Lozenges, 20 mg + 10 mg - 30 pcs.

10. Storage conditions

  • Complete protection from the sun's rays;
  • Complete protection against unauthorized access.
Recommended storage temperature for Lysobact- not higher than 25 degrees. Recommended shelf life- different, indicated on the packaging and depends on the manufacturer.

11. Composition

1 tablet:

  • lysozyme hydrochloride - 20 mg;
  • pyridoxine hydrochloride - 10 mg;
  • Excipients: lactose monohydrate, gum tragacanth, magnesium stearate, sodium saccharinate, vanillin.

12. Terms of dispensing from pharmacies

The drug is released without a prescription.

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* Instructions for medical use for the drug Lizobakt published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST

Lysobact is a fast-acting antiseptic drug that has a detrimental effect on pathogenic bacteria, viruses and fungi. This effect can be achieved due to the composition of the drug, namely, its active components.

Lysozyme is a protein enzyme that promotes the destruction of pathogens. In addition, it is involved in creating a general defense of the immune system and in particular the mucous membranes of the throat and oral cavity.

Pyridoxine is a substance that has an anti-aphthous effect on the oral mucosa. The component has an independent effect, without affecting the pharmacodynamics of lysozyme.

After taking the substance, the tablets are rapidly absorbed in the gastrointestinal tract. Their biological activity is laid in the liver, muscles, central nervous system and other organs of internal secretion.

Pyridoxine is absorbed through soft tissues, can pass through the placental barrier and be excreted in breast milk. That is why taking the drug during pregnancy and lactation should be used under the strict supervision of the attending physician.

The active components of the drug are metabolized in the liver and excreted through the urinary tract.

This page contains detailed instructions for use. Lizobakta. The available dosage forms of the drug (lozenges), as well as its analogues, are listed. Information is provided on the side effects that Lyzobact can cause, on interactions with other drugs. In addition to information about the diseases for the treatment and prevention of which the drug is prescribed (tonsillitis, stomatitis, gingivitis), the algorithms for admission, possible dosages for adults and children are described in detail, the possibility of use during pregnancy and lactation is specified. Annotation to Lizobakt is supplemented by reviews of patients and doctors. The composition of the drug.

Instructions for use and regimen

The drug is applied topically in the oral cavity. Adults and children over 12 years of age are prescribed 2 tablets 3-4 times a day, children aged 3-7 years - 1 tablet 3 times a day, children aged 7-12 years - 1 tablet 4 times a day. The course of treatment is 8 days.

Tablets of the drug Lizobakt should be slowly absorbed, not chewed, holding the melted mass of the tablet in the oral cavity for as long as possible, until completely dissolved.

Compound

Lysozyme hydrochloride + Pyridoxine hydrochloride + excipients.

Release forms

Lozenges.

Lizobakt- an antiseptic of combined composition for local use in ENT practice and dentistry. The action of the drug is due to its constituent components.

Lysozyme is an enzyme of a protein nature (mucolytic enzyme mucopeptide-N-acetylmuramyl hydrolase) and is used as an antiseptic (causes lysis of the cell membrane of gram-positive and gram-negative bacteria, as well as fungi and viruses). Takes part in the regulation of local nonspecific immunity.

Pyridoxine has a protective effect on the oral mucosa (has an anti-aphthous effect). Does not affect the pharmacodynamic properties of lysozyme.

Indications

Treatment of infectious and inflammatory diseases of the oral mucosa, gums and larynx:

  • gingivitis;
  • stomatitis;
  • angina, tonsillitis;
  • catarrhal phenomena of the upper respiratory tract;
  • aphthous ulcers;
  • herpetic lesions of the oral mucosa (as part of complex therapy);
  • erosion of the oral mucosa of various etiologies.

Contraindications

  • hereditary lactose intolerance, lactase deficiency or glucose / galactose malabsorption syndrome;
  • children's age up to 3 years;
  • hypersensitivity to the components of the drug.

special instructions

In the event of an allergic reaction, the use of the drug should be discontinued.

Side effect

  • allergic reactions.

drug interaction

When used together, Lizobakt enhances the therapeutic effect of antibiotics, incl. penicillin, chloramphenicol, nitrofurantoin, enhances the action of diuretics, weakens the activity of levodopa.

Isoniazid, penicillamine, pyrazinamide, immunosuppressants, estrogens, and oral contraceptives may increase the need for pyridoxine (pyridoxine antagonism or increased renal excretion).

Analogues of the drug Lizobakt

Lyzobakt has no structural analogues for the active substance.

Analogues by pharmacological group (antiseptics and disinfectants):

  • Agisept;
  • Aldesol;
  • Anti Angin Formula;
  • Aseptolin plus;
  • Ascocept;
  • Astracept;
  • Geksoral tabs;
  • Dr. Theiss Angi Sept;
  • Dr. Theiss Sage Extract with Vitamin C;
  • Drill;
  • Ingalipt;
  • Iodinol;
  • Iodonate;
  • Koldakt Lorpils;
  • Lugol;
  • Neo angina;
  • Pulmex;
  • Rinza Lorcept;
  • Sebidin;
  • Septogal;
  • Septolete;
  • Stopangin;
  • Strepsils;
  • Suprima ENT;
  • TheraFlu LAR;
  • Travisil;
  • Faringopils;
  • Fukaseptol.

Use in children

Contraindicated in children under the age of 3 years.

Use during pregnancy and lactation

Perhaps the use of the drug Lizobakt according to indications during pregnancy and lactation (breastfeeding).

Lysobact is an antiseptic drug that has a local effect. Scope - dentistry and ENT practice.

The active substance lysozyme (an enzyme of a protein nature), which is part of the composition, is an effective antiseptic and regulator of local immunity, and pyridoxine protects the oral mucosa without reducing the action of lysozyme.

In this article, we will consider why doctors prescribe Lizobakt, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Lizobakt can be read in the comments.

Release form and composition

Dosage form of Lizobakt - lozenges: round-shaped with a dividing line on one side, white with a yellow or cream tint or white (10 pieces in blisters, 3 blisters in a carton box).

  • Pyridoxine hydrochloride - 0.01 g;
  • Lysozyme hydrochloride - 0.02 g.

Clinical and pharmacological group: antiseptic for local use in ENT practice and dentistry.

What is Lizobakt used for?

Lizobakt is prescribed for the treatment of infectious and inflammatory diseases of the mucous membrane of the gums, oral cavity and larynx:

  1. Stomatitis;
  2. Gingivitis;
  3. aphthous ulceration;
  4. Erosion of the oral mucosa, having a different etiology;
  5. Herpetic lesions of the oral mucosa (simultaneously with other drugs);
  6. Catarrhal phenomena (inflammation of the mucous membrane) of the upper respiratory tract.


pharmachologic effect

Analgesic, antiseptic, anti-inflammatory local. Antiseptic for local use in ENT practice and dentistry. Lysozyme is an enzyme of a protein nature (mucolytic enzyme mucopeptide-N-acetylmuramyl hydrolase) and is used as an antiseptic (causes lysis of the cell membrane of gram-positive and gram-negative bacteria and fungi), it also has antiviral activity.

Pyridoxine promotes the regeneration of the oral mucosa and has an anti-aphthous effect.

Instructions for use

For those who use Lizobakt, the instructions for use inform that this drug is intended for topical use.

  • Children whose age has reached 12 years or more, as well as adult patients, are prescribed 2 tablets. 3-4 times a day.
  • Children aged 3 to 7 years Lizobakt appoint 1 table. 3 times a day, and from 7 to 12 years - 1 tab. 4 times a day.

Tablets must be slowly absorbed, keeping the melted mass in the oral cavity as long as possible (until complete dissolution).

Contraindications

The use of Lizobakt is contraindicated against the background of:

  1. Hypersensitivity to active substances (lysozyme and pyridoxine) and auxiliary components.
  2. hereditary lactose intolerance.

In pediatrics, the drug is prescribed from the age of three.

Side effects

The drug almost never causes side effects. In some cases, there were local allergic reactions caused by individual intolerance to one of the active components of the drug. These phenomena disappear after refusing to take the medicine.


Pregnancy and lactation

Perhaps the use of the drug Lizobakt during pregnancy and lactation (breastfeeding).

Lizobakt: cheaper analogues

There are no analogues of Lyzobact identical in composition. According to the impact on the pathogenic microflora in the oral cavity, cheaper analogues include:

  • Imudon, Faringosept, Grammidin, Strepsils, Septolete, Sebidin, Neo-Angin, Adzhisept and many others.

However, when choosing any analogue, it should be borne in mind that the principle of their action, as well as contraindications and side effects of these drugs, are completely different.

Prices

Lizobakt refers to not very expensive medicines. Its average cost in Russian pharmacies is about 280 rubles.

Terms of dispensing from pharmacies

The drug is approved for use as a means of OTC.

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