What you need to know about nise ointment. Nise tablets: what are the analogues of the drug

Inflammatory formations on the skin require the use of special preparations for external use. The action of such funds is aimed at reducing unpleasant symptoms, eliminating swelling of the skin.

One of these drugs is Nise ointment, the instructions for use contain detailed information on the rules for use.

What helps Nise ointment?

The drug Nise for external use has a general anti-inflammatory effect on the lesion, is used to eliminate the symptoms of pain.

Most often prescribed for the following situations:

  • arthritis;
  • gout;
  • psoriatric arthritis;
  • osteochondrosis;
  • osteoarthritis;
  • radiculitis;
  • inflammatory formations on ligaments and tendons;
  • joint damage;
  • damage to soft tissues with the presence of inflammation;
  • unpleasant symptoms in the postoperative period;

It can be used for pain symptoms in the muscles after prolonged physical exertion.

Composition and form of release

The medicinal substance Nise for external use does not contain hormones, it is used for complex therapy for the treatment of large numbers of diseases.

The drug Nise for external use is available in the form of a white gel with a specific odor.

The composition of the medicinal substance:

  • nimesulide;
  • propylene glycol;
  • macrogol;
  • isopropanol;
  • butylhydroxyanisole;
  • dihydrogen phosphate;
  • menthol;
  • purified water.

Produced in a plastic tube of 20, 50 mg, which is located in a cardboard box.

Operating principle

The drug Nise belongs to a new generation of substances to eliminate the pain symptom. The active component nimesulide, when using the substance, penetrates into the damaged area, reduces the development of the inflammatory process.

The drug quickly eliminates pain and reduces tissue swelling. Menthol soothes the epidermis, prevents the formation of allergic reactions. Additional components of the gel, when applied, have an antiseptic effect. The use of Nise allows you to narrow the blood vessels, eliminate unpleasant symptoms.

Good to know! In the inflammatory process, a decrease in the level of blood circulation is very often observed, the medicinal substance normalizes blood circulation, blocks the further development of the disease.

Instructions for use of the drug

  • clean the surface of the epidermis with warm water and dry with a towel;
  • apply a small amount of the product to the skin, spread in a thin layer;
  • the drug remains on the skin until completely absorbed;
  • it is recommended to apply the product 3 times a day;
  • with complex types of the disease, the dosage may be increased by the attending physician;
  • the duration of treatment is not more than 10 days.

The helium structure of the substance allows the product to be evenly distributed and not to clog the pores of the epidermis.

Stories from our readers!
"I cured my sore back on my own. It's been 2 months since I forgot about the pain in my back. Oh, how I used to suffer, my back and knees hurt, lately I couldn't really walk normally ... How many times I went to polyclinics, but there they only prescribed expensive pills and ointments, which were of no use at all.

And now the 7th week has gone, as the joints of the back do not bother a bit, in a day I go to the country to work, and from the bus it’s 3 km, so I walk easily! All thanks to this article. Anyone with back pain should read this!

Contraindications for use

  • individual sensitivity to the components of the drug;
  • pregnancy and breastfeeding period;
  • the presence of open wounds on the epidermis;
  • age up to 7 years;
  • liver and kidney disease;
  • dermatosis;
  • infectious rashes on the epidermis.

Note! For the elderly, it is necessary to use the drug with caution to prevent complications of the course of the disease.

Side effects and overdose

During the period of use of Nise, the following side effects may occur:

  • allergy;
  • dizziness;
  • swelling of the skin;
  • increased sweating;
  • nausea.

With the correct use of the medicinal substance, cases of overdose are quite rare. However, with the self-appointment of Nise, the following overdose symptoms may appear: nausea, swelling of the skin, general weakness, dizziness, a rash on the epidermis in the form of blisters.

If such symptoms appear, it is necessary to stop using the drug and contact a medical institution.

Pain and crunch in the back over time can lead to dire consequences - local or complete restriction of movement, up to disability.

People, taught by bitter experience, use a natural remedy recommended by orthopedists to cure their back and joints...

The cost of ointment Nise

A drug in the form of a gel for external use has an average cost of 80 rubles for 20 mg, 170 rubles for a 50 mg tube.

drug interaction

It is forbidden to use the drug Nise with the substances digoxin, phenytoin, diuretics, methotrexate. It is not used in conjunction with diabetic drugs.

Analogues and their cost

If you need to use drugs of a similar action, you can purchase the following types:

  1. Nimesulide - a drug in the form of a gel has the same properties as Nise. The average cost is 130 rubles.
  2. Nimulide - the active component of the drug nimesulide, is an analogue of the drug Nise, is widely used to eliminate inflammation and pain symptoms. The price is 120 rubles.
  3. Naisulid - is the cheapest analogue of Naise, has the ability to relieve inflammation and swelling of the skin. The price is 60 rubles.
  4. Nimik - the drug has the property of deep penetration and elimination of unpleasant symptoms. The average price is 150 rubles.

Note! Before using any similar drug, you should consult a doctor. Each analogue may contain additional components that may cause unforeseen side effects.

User Reviews

After undergoing surgery in the knee joint, pain appeared, which had a chaotic character. I use Nise for external use 2 times a day during an exacerbation of pain. Quickly eliminates discomfort and reduces swelling of the skin.

Elena, 37 years old

I go in for an active sport and very often suffer from stretching of muscle tissue. Nise comes to the rescue. After several applications, the unpleasant symptoms disappear.

Artur, 26 years old

I used a remedy to eliminate back pain, after the second day of use, redness appeared on the skin and itching. Now I use drugs to eliminate an allergic reaction.

Nise gel is used for topical application of the locomotor apparatus, reduces the feeling of stiffness, increases motor reflexes, removes swelling of the joints. This is a medical product of the latest generation of sulfonanilides - anti-inflammatory non-steroidal drugs. It is used to relieve symptoms and treat ailments of the musculoskeletal system, such as various forms of gout, arthritis of all forms, osteochondrosis, sciatica. This medicine is also recommended for use after varying degrees of injuries, bruises, torn ligaments. Effectively counteracts pains of various forms.

1. Pharmacological action

An anti-inflammatory drug of non-steroidal origin for external use, which has an analgesic effect.

2. indications for use

  • Various rheumatoid;
  • Various inflammatory diseases of the joints and articular components;
  • Inflammatory diseases of the peripheral nerves;
  • Inflammatory diseases of soft tissues due to trauma.

3. How to use

  • Recommended dosage: Apply a thin layer of the drug to the affected area of ​​the body, without rubbing no more than four times a day;
  • Maximum dosage: 30 g of the drug per day;
  • Recommended duration of treatment: no more than ten days.
Application Features:
  • After use, wash your hands well with detergent;
  • It should be used only on areas of skin with no damage;
  • Use in patients suffering from functional disorders of the liver or kidneys should be used with caution.

4. Side effects

  • Central nervous system: dizziness, headaches;
  • Urinary system: the appearance of blood in the urine, fluid retention;
  • Damage to the skin: discoloration of the skin, itching at the site of application;
  • Digestive system: nausea, pain in the stomach, ulcerative lesions of the digestive system, increased activity of liver enzymes, erosive lesions of the digestive system, heartburn, vomiting;
  • Hematopoietic system: decrease in the number of leukocytes, increase in the number of agranulocytes, decrease in the number of platelets, decrease in the amount of hemoglobin, prolongation of bleeding time;
  • Hypersensitivity reactions to Nise gel: skin rashes.

5. Contraindications

  • The use of Nise gel during pregnancy;
  • Infectious diseases of the skin at the site of application;
  • Hypersensitivity to Nise gel or its components;
  • The presence of dermatoses at the site of application of Nise gel;
  • Individual intolerance to Nise gel or its components;
  • Damage to the skin at the site of application;
  • The use of Nise gel during breastfeeding.

6. During pregnancy and lactation

During pregnancy, the use of Nise gel is contraindicated.

During lactation, the use of Nise gel is contraindicated.

7. Interaction with other drugs

Simultaneous use of Nise gel with Digoxin, drugs containing lithium, blood pressure lowering drugs, blood thinners, Methotrexate, Phenytoin, diuretics, non-steroidal anti-inflammatory drugs, Cyclosporine or glass melting drugs that reduce blood glucose levels, leads to the occurrence of drug interactions due to the competition of the listed drugs with Nise gel for protein binding.

8. Overdose

Cases of overdose with Nise gel are not described.

9. Release form

Gel for external use, 1% - 20 or 50 g.

10. Storage conditions

Nise gel is stored in an inaccessible place.

11. Composition

One gram of Nise gel:
  • 10 mg nimesulide;
  • 50 mg menthol;
  • 100 mg methyl salicylate;
  • 250 micrograms of capsaicin.

12. Terms of dispensing from pharmacies

The drug is released without a prescription.

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* Instructions for medical use for Nise gel are published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, IT IS NECESSARY TO CONSULT WITH A SPECIALIST

Efficiency

Easy to find in pharmacies

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Joint pains in various pathologies are so intense that not only worsen the general well-being of the patient, but also significantly reduces the quality of his life. Today, pharmacological companies have developed a large number of drugs that help in the fight against the painful symptoms of joint diseases. One of these drugs is Nise Gel, which is popular not only among patients, but also among specialists.

Pharmacological action of the drug

Nise is a non-steroidal anti-inflammatory drug of the latest generation, belonging to the class of sulfonanilide. Included in it nimesulide has a local analgesic, anti-inflammatory and antipyretic effect. This effect is due to the selective "switching off" of cyclooxygenase-2 and some other mechanisms.

methanol, which is also present in the preparation, acts as a local liquefying, analgesic, antipruritic substance. Methanol is also an antiseptic and a local sedative. The effect of methanol on the site of application is due to reflexes that are associated with irritation of the nerve endings of the receptors of the skin, mucous membranes. Stimulates the production and release of substances that are involved in the regulation of pain, vascular permeability and other processes, providing a distracting, antipruritic effect. Local external application of the substance is accompanied by vascular constriction, a feeling of coldness, which gradually turns into a feeling of slight burning and tingling. The trophism of tissues improves reflexively, the tone of blood vessels located both on the surface and deep in tissues and organs changes.

Nise also contains methyl salicylate, which, when applied topically, rapidly penetrates deep under the skin, is absorbed and hydrolyzed, after which it turns into an anion of salicylic acid. The substance actively inhibits cyclooxygenase, reduces the synthesis of prostaglandins, which are responsible for the inflammatory process, soreness, swelling and fever. It normalizes capillary permeability, which is much increased during inflammation, improves microcirculation, reduces swelling and inflammation, reduces the intensity of pain in various pathological processes in the joints, muscles and tissues.

Release form

Transparent pale yellow or white gel without foreign particles. The drug is produced in 20 and 50 gram aluminum tubes. Each individual tube is placed in an individual cardboard box along with instructions for using the drug.

Ask your question to a neurologist for free

Irina Martynova. Graduated from the Voronezh State Medical University. N.N. Burdenko. Clinical intern and neurologist of BUZ VO "Moscow polyclinic".

Compound

    1 g of external agent contains active substances:
  • nimesulide - 10 mg;
  • methyl salicylate - 100 mg;
  • methanol - 50 mg;
  • capsaicin - 0.250 mg.
    Auxiliary ingredients are:
  • diethyl phthalate - 50 mg;
  • ether monoethyl diethylene glycol - 50 mg;
  • polyoxylcastor oil - 50 mg;
  • propylene glycol - 70 mg;
  • sodium benzoate - 1 mg;
  • disodium salt of ethylenediaminetetraacetic acid - 1mg;
  • butylated hydroxytoluene - 0.4 mg;
  • non-toxic gelling agent Carbomer-980 - 12 mg;
  • trometamol - 2 mg;
  • distilled water.

Instructions

Indications

    • It is indicated for external local use to eliminate pain in the following conditions:
    • inflammation of the synovial bag - bursitis;
    • inflammation of the synovial articular membrane - synovitis;
    • chronic pain in the lumbar region -;
    • inflammation of the joints
    • deforming diseases of the joints of a non-inflammatory nature - osteoarthritis and osteoarthritis;
    • inflammation of the tendons - tendonitis;
    • soreness along the nerve -;
    • muscle pain associated with hypertonicity - myalgia;
    • inflammation of the inner lining of the tendon sheath - tendovaginitis;


  • ankylosing spondylitis;
  • rheumatism;
  • pathology of tissues and joints caused by metabolic disorders -;
  • pathology of the spinal nerve roots -;
  • pain symptoms in the spinal column, muscles and joints of unclear etiology.

Mode of application

The drug is suitable exclusively for external use! The use of Nise Gel inside is strictly prohibited.

Use for the treatment of joint pain must be strictly according to the official instructions for use. It is very important to follow the recommended dosage and frequency of use.

The main rules of application are:

  1. The area of ​​the skin to which the drug is applied must be cleaned with water and soap and thoroughly dried with a towel.
  2. The place of application should be intact, open ulcers and various skin inflammations should be absent.
  3. Multiple dosage of the drug should be no more than 3 cm of the squeezed out gel from the tube.
  4. Apply the product only to the area in which pain is felt.
  5. The drug is applied in a thin layer, it should not be rubbed into the skin. The product should be absorbed into the skin on its own.
  6. The frequency of use of the drug is 1 time in 8-12 hours.
  7. The gel is not recommended for use under bandages that do not allow air to pass through.
  8. Strictly ensure that the gel does not get on the mucous membrane of the eye. In case of eye contact with the gel, rinse with plenty of clean water.
  9. After using the gel, wash your hands thoroughly with soap and water.
  10. After using the drug, the tube with the gel should be tightly closed.

Contraindications

Like all drugs, Nise has a number of contraindications, which include:

    • hypersensitivity to one of the components of the gel;
    • acute lesions of the organs of the digestive system with ulcers or erosions;
    • stomach/intestinal bleeding;


    • dermatoses of various etiologies, damage to the upper layers of the skin;
    • infectious diseases of the skin;


  • violation of the integrity of the skin at the site of application of the gel;
  • acute renal failure;
  • pathological processes in the hematopoietic system;
  • bronchospasm caused by the use of others in history;
  • the period of bearing a child;
  • breastfeeding period;
  • age of patients younger than 7 years.

Nise Gel is used with extreme caution in cardiovascular pathologies, hypertension, type 2 diabetes mellitus, and elderly patients.

Side effects

side effects when using Nise Gel externally enough but, nevertheless, they have a place to be.
Rarely, local reactions occur in the form of itching, urticaria, peeling of the skin, discoloration of the skin at the site of application of the drug, burning sensation. Such side effects, as a rule, do not require the abolition of the drug and disappear on their own within a few days.

Use of the gel a large area of ​​skin or prolonged use may cause a number of systemic reactions, such as:

  • burning sensation in the larynx, behind the sternum;
  • feeling of nausea with bouts of vomiting;
  • digestive disorders;
  • formations on the mucous membrane of the digestive tract of ulcers and small erosions;
  • increased activity of liver transaminases;
  • migraine and headache;
  • feeling of dizziness;
  • fluid retention in the body;
  • manifestation of allergic reactions, up to anaphylactic shock;
  • thrombocytopenia, anemia, leukopenia and other disorders in the blood test.

If at least one of the above symptoms occurs, the use of the drug should be stopped and seek help from your doctor.

Overdose

The official instructions for the drug do not indicate data on cases of overdose.. The only thing to remember is the risk of developing systemic side effects that can develop with a single dose of the drug at a dosage of 50g or more. Since there is no specific antidote, if an overdose is suspected, urgent medical attention should be sought.

Use during pregnancy and lactation

The use of the gel by pregnant women is prohibited.. For the treatment of joint pain in this case, you should consult a gynecologist who recommends analogues of the drug. If there is an urgent need to use Nise Gel during lactation, breastfeeding should be interrupted for the entire period of therapy.

drug interaction

Nise Gel should be used with caution concomitantly with phenytoin, digoxin, preparations containing lithium, cyclosporine, diuretics, other non-steroidal anti-inflammatory drugs, antihypertensives and hypoglycemic drugs. If the patient uses such medicines, this should be reported to the attending physician who prescribes the use of the drug.

Advantages

Comparing Nise Gel with its analogues, a number of advantages can be identified:

  1. Clinical trials have shown that it is the safest to use(with the exception of cases falling under "contraindications"). The gradual absorption of active substances into the muscles and synovial joint fluid provides a slight concentration of components in the blood. Using this drug according to the instructions, it does not adversely affect the body. All components are completely excreted from the body with the help of the liver..
  2. Nise Gel meets all requirements, which, according to WHO, drugs must comply with local application, namely:
  • possessing an analgesic drug, which ensures high efficiency of therapy;
  • the absence of local toxic reactions, allergic manifestations that the medicine can cause;
  • the ability to quickly reach the "center", being absorbed through the layers of the skin;
  • the concentration of the components of the drug in the blood does not reach the level when there is a risk of side effects;
  • the exchange and excretion of the drug from the body are the same as with systemic use.

Price

The average price of Nise Gel 20 mg is 160-190 rubles;

The average price of Nise Gel 50 mg is 300-315 rubles.

Conditions for dispensing the drug

Nise Gel is a drug that can be purchased at pharmacy chains without presenting a prescription.

Storage

The gel is stored in a tightly closed tube away from direct sunlight. The storage temperature of the drug should not exceed 24°C. It is impossible to allow the product to freeze, as in this case it loses all its medicinal properties.

The drug should be stored out of reach of children.

Best before date

The drug is suitable for use within 24 months from the date of its manufacture, the date of which is indicated on the carton.

Analogues

According to the active substances included in the preparation, Nise Gel has the following analogues:

  • Sulaidin.

According to the therapeutic effect, there are the following analogues of the drug:


  • Bioran Gel;
  • etc.

It should be noted that the use of Nise Gel and its analogues should be agreed with a specialist.

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Efficiency

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Easy to find in pharmacies

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Semyon

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Efficiency

Efficiency

Diseases of the musculoskeletal system are very common among modern people. This is largely due to the way of life - the lack of systematic and complete physical activity. But in addition, all kinds of injuries and hereditary predisposition contribute to their development. Treatment of any diseases of the musculoskeletal system should be comprehensive, and include the use of systemic and local remedies. The Nise gel belongs to the latter, we will clarify what the instructions for using such a medicine say, we will give real reviews about its use, and also say if there are analogues of the Nise gel, and what it helps in general.

So, Nise-gel is a fairly popular drug that belongs to the group of non-steroidal anti-inflammatory drugs. It is based on the active ingredient nimesulide.

What helps Nise-gel?

The active component of Nise-gel acts mostly locally, practically without penetrating into the blood. Nimesulide has analgesic and anti-inflammatory properties. Due to these properties, this medication can be prescribed to patients with diseases of the musculoskeletal system, which are inflammatory or degenerative. It is used mainly as part of a complex treatment, namely as a local symptomatic remedy.

Nise-gel can be used to correct the manifestations of articular syndromes in patients suffering from exacerbation of gout. It is used to treat rheumatoid and psoriatic arthritis. Such a drug can be prescribed to patients with ankylosing spondylitis. Among the indications for its use are osteoarthritis, as well as osteochondrosis with the so-called radicular syndrome.

Among other things, Nise-gel can be quite effective in the treatment of sciatica.

The anti-inflammatory and analgesic qualities of this medication make it possible to use it to correct inflammatory lesions of the ligaments and tendons. It can also help patients with bursitis and sciatica. Sometimes it is recommended to use it for lumbago.

Nise-gel copes quite well with muscle pain that occurs against the background of rheumatic or non-rheumatic diseases. Also, such a remedy effectively relieves discomfort and pain during post-traumatic inflammation of soft tissues or the musculoskeletal system, namely with various injuries or torn ligaments, and also with all kinds of bruises.

It is advisable for readers of "Popular about Health" to discuss the feasibility of using Nise-gel with their doctor.

How to use Nise-gel correctly?

The Nise gel instructions specify that this drug is intended exclusively for external use. It is applied only to clean skin: it must first be washed and then dried. Nise-gel should be carefully distributed over the affected areas, squeezing out three centimeters of the drug. The gel does not need to be rubbed into the skin, it should spread over the skin evenly, in a thin layer.

Nise-gel can be applied up to four times a day with an equal time interval. The duration of therapy with this medication can reach one and a half weeks, but no more.

Are there any contraindications?

Nise-gel, like any other drug, should not be used in the presence of individual intolerance (allergy) to the components of this drug. It is worth noting that the remedy is contraindicated even if the patient has a history of bronchospasm provoked by acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.

Nise-gel should not be applied to skin with dermatosis, epidermal damage and manifestations of a skin infection. Also, such a medication is contraindicated in preschool children, pregnant and lactating women.

Despite the fact that the components of Nise-gel practically do not penetrate into the bloodstream, it is not recommended for use in erosive and ulcerative lesions of the digestive tract, with bleeding in the gastrointestinal tract, with serious disorders in the activity of the kidneys or liver. Also, the remedy is not prescribed to patients with heart failure, hypertension, type 2 diabetes mellitus and the elderly.

Possible side effects

In most cases, Nise-gel is well tolerated by patients, occasionally allergic reactions of varying severity may occur. With prolonged use or when using a significant amount of gel (or when applied to a large area of ​​the skin), systemic side effects may develop - gastrointestinal disturbances, headaches, dizziness, swelling, etc.

What are Nise gel analogues?

On sale you can find medicines that are almost completely similar to Nise-gel. These are drugs Nimesulide, Aponil, Sulaidin and Nimulide. Also in pharmacies there are medicines that are similar in effect. The doctor will help you choose a suitable substitute for the prescribed remedy.

The drug Nise gel is a proven remedy for eliminating inflammation, pain and swelling in many pathologies of the musculoskeletal system. After application, the composition actively acts on the affected area, but practically does not penetrate into the bloodstream, which reduces the risk of unwanted reactions.

In the instructions for Nise gel, the manufacturer indicates important points on the use and action of the NSAID group. Subject to the recommendations, side effects appear infrequently, the drug actively eliminates negative symptoms.

Composition and action

Ointment Nise (gel) is an important element in the treatment of pathologies of the spine and back. The composition with nimesulide is a new generation drug for eliminating pain, inflammation in case of damage to bone and cartilage structures, muscles and joints.

The active ingredient in Nise gel is nimesulide. 1 g of the composition contains 10 mg of the active ingredient. In pharmacies, you can buy a tube with 50 g of the drug. The main advantage of new types of NSAIDs is a selective action, selective blocking of pain and inflammation mediators without a negative effect on the beneficial enzyme cyclooxygenase-1.

After application, nimesulide gradually penetrates into the affected tissues, synovial fluid and joints, blocks the production of cyclooxygenase-2, prevents the synthesis of leukotrienes and prostaglandins, which cause negative reactions. The result of therapy is a decrease in pain, swelling, suppression of inflammation. After the disappearance of negative symptoms, the mobility of problem joints improves, and the stiffness of the affected area decreases. The components of the drug based on nimesulide are completely excreted from the body, do not affect the composition of the blood plasma and the functioning of the central nervous system.

The manufacturer offers not only Nise gel, but also other dosage forms: suspension, oral tablets and a dispersible variety (effervescent tablets).

Indications for use

What helps Nise gel? A local remedy based on nimesulide is effective in the following diseases:

  • rheumatism;
  • bursitis;
  • inflammation of cartilage, joints, bone tissue after injuries and injuries;
  • gout;
  • osteoarthritis;
  • ankylosing;
  • arthralgia;
  • synovitis;
  • pain in the spine;
  • tendovaginitis.

What if from the back? Read about symptoms and treatments for possible conditions.

The page is written about the types of pathology, characteristic symptoms and effective methods of treating myalgia.

Contraindications

Despite a "softer" effect on the body, the drug based on nimesulide has limitations. It is important to find out the presence of contraindications before starting therapy in order to prevent side effects.

Nise gel is not prescribed in the presence of the following conditions and pathologies:

  • erosion and ulcers of the digestive tract (with an exacerbation of the process);
  • excessive sensitivity to the active substance - nimesulide or other components of NSAIDs;
  • bleeding in the body of any etiology and intensity;
  • age up to 8 years;
  • hepatitis, cirrhosis of the liver, high levels of liver enzymes;
  • on the affected area there are wounds, scratches, purulent nodules, dermatosis develops;
  • pregnancy;
  • severe kidney damage;
  • lactation period;
  • the patient had previously recorded bronchospasm after the use of non-steroidal anti-inflammatory compounds.

On a note! With high blood pressure, in old age, with severe heart disease, diabetes mellitus (type II), care must be taken when prescribing a drug based on nimesulide. The development of adverse reactions is a reason for discontinuing the drug, re-consulting with the attending physician.

Instructions for use

Apply the drug Nise in the form of a gel only externally, to the painful area. The tool is not suitable for processing large areas.

  • before applying the composition, wash, dry the problem area;
  • squeeze a small amount of Nise gel (the best option is no more than 3 cm) onto the painful area, rub it, but without strong pressure;
  • after treatment, there should be a thin layer of local agent on the surface of the epidermis;
  • some patients feel a slight burning sensation, but after 5-6 minutes the discomfort disappears;
  • during processing, you need to ensure that the drug does not get into the eyes, mouth, mucous membranes. After the procedure, be sure to carefully remove the remnants of the gel from the hands, wash and wipe the skin dry so that no particles of the drug remain on the fingers and palms;
  • the frequency of application of the anti-inflammatory composition is 3 or 4 times a day. To achieve a lasting effect, you need to apply the gel daily to the affected area;
  • the maximum duration of therapy is 10 days. It's important to know: if after 2 weeks there is no noticeable improvement, then it is necessary to pay a visit to a vertebrologist or neurologist, choose a substitute or NSAID based on another active substance.

Side effects

Against the background of the individual characteristics of the organism, undesirable manifestations are possible. In most cases, negative symptoms occur when instructions are violated, excessive intake of nimesulide into the body over a long period. Characteristic reactions appear locally: swelling, redness, spread of the rash on the treated area.

With an overdose, the risk of negative symptoms is increased:

  • dizziness;
  • diarrhea, nausea, vomiting;
  • pronounced swelling, fluid retention;
  • dizziness;
  • development of liver failure.

Nimesulide is poorly absorbed into deep tissues, there is practically no systemic effect: after a day, the concentration of the active substance in the bloodstream is 300 times lower than with oral administration of the drug. The use of Nise gel according to the instructions allows you to avoid side effects. Most negative reactions occur with prolonged use of the composition, processing large areas.

drug interaction

Some groups of drugs should be used with caution during treatment with a new generation of NSAIDs. For this reason, it is forbidden to purchase a drug for external application to problem areas if certain formulations of other categories have been previously prescribed.

It is undesirable to combine Nise gel with:

  • diuretics;
  • cyclosporins;
  • drugs Phenytoin, Digoxin;
  • hypoglycemic agents for oral administration;
  • lithium preparations;
  • formulations to lower blood pressure;
  • other types of non-steroidal formulations to eliminate inflammation, swelling and pain in cartilage, bone and muscle tissue.

What is it, what are the symptoms of the disease and how to be treated? We have an answer!

The rules for the use of the Neurobex Neo vitamin complex as part of the complex therapy of diseases of the spine are described on the page.

Go to the address and read about the symptoms of a pinched nerve in the spine in the thoracic region and about the methods of treating the pathology.

Price

An effective drug Nise gel is a selective action (of a new generation), but unlike many drugs in this category, the cost of a local remedy is suitable for most patients. The price of Nise gel is from 170 to 220 rubles (50 g). You don't need a prescription to purchase an anti-inflammatory compound. For storage, a room with a temperature of up to +25 C is suitable, without excessive dampness.

Gel Nise: analogues

As prescribed by the doctor, the patient can purchase another remedy based on Nimesulide. Non-steroidal anti-inflammatory drugs of the new generation are safer for the body, systemic reactions occur less frequently.

Nise gel is a modern drug, after the use of which patients feel relief from osteochondrosis, sciatica, lumbago, arthralgia, myositis, after injuries and severe bruises / sprains. Nimesulide does not have a systemic effect, negative symptoms during therapy appear in a small number of cases. The composition for external use reduces negative symptoms without negative effects on the central nervous system and circulatory system.

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