Hypotrophy 1 tbsp. Hypotrophy in children: causes and treatment for underweight children. Lack of essential fatty acids

Hypotrophy in children is a diagnosis associated with malnutrition of the child, which is accompanied by insufficient body weight gain in accordance with age and height. Most often occurs in babies under the age of three years, can be observed in newborns. This condition is dangerous because it entails other serious disruptions in the body, up to a lag in mental development. Therefore, it is important to know about this disease, its symptoms, in order to detect its manifestations in time.

About malnutrition in young children can be said with a lack of body weight of 10% of the age norm or more. Depending on the neglect of the disease, there are three degrees of it.

The first degree is usually invisible, it can be skipped, taking it as a feature of the physique. Or vice versa, the baby can really be thin by nature, so the doctor can identify hypotrophy of the 1st degree in children. Its symptoms include:

• loss of appetite;
• sleep disorders;
• anxiety;
• possible decrease in muscle tone;
• pallor of the skin and a decrease in its elasticity;
• the child may look thin in the abdomen;
• rarely - signs of anemia or rickets.

Hypotrophy of the 2nd degree in children will already be noticeable to parents on the following grounds:

• weight deficit from 20 to 30%;
• growth retardation (3-4 cm);
• bad sleep;
• lethargy, lethargy;
• poor appetite, frequent regurgitation;
• stool disorders - constipation and diarrhea;
• cold extremities;
• poor skin condition: pallor, peeling and dryness;
• pronounced thinness of the body;
• lag in psychomotor development;
• possible tachycardia and shortness of breath;
• frequent colds.

With the third degree of the disease, the child's condition becomes almost critical:

• weight deficit of more than 30%;
• lag in growth of 8-10 cm;
• the bones are covered with leather;
• gray, dry skin;
• drowsiness, tearfulness, apathy;
• in infants - sinking of the fontanel;
• loss of previously acquired skills;
• muscles atrophy;
• mental underdevelopment;
• chronic infections (pyelonephritis, pneumonia) are possible;
• cracks in the corners of the lips;
• stool disorders, frequent vomiting.

Types of malnutrition

In addition to the degrees of development, malnutrition is divided according to the time of onset of the disease into intrauterine (congenital) and acquired.

Congenital malnutrition

This type of pathology is also called intrauterine, and develops during the period of gestation by the mother. Reasons for this type:

• toxicosis in the mother in the first and second trimester of pregnancy;
• fetoplacental insufficiency,;
• bad habits of a pregnant woman, poor nutrition;
• chronic diseases of the expectant mother (cardiac, endocrine, diabetes mellitus, pyelonephritis, etc.);
• stress;
• genetic abnormalities of the fetus;
• mother's work in hazardous production during pregnancy;
• problems with the placenta;
• — fetal hypoxia —;
• intrauterine infection.

You can determine intrauterine disease after birth by the following symptoms: too low weight and height, violation of thermoregulation, decreased muscle tone, slow healing of the umbilical wound, weak expression of reflexes.

Acquired malnutrition

The causes of this type of pathology can be divided into external and internal. Internal causes include various diseases and pathologies in a child, including congenital (metabolic disorders, endocrine diseases, immunodeficiency, malformations, food allergies, lactase deficiency, celiac disease, cystic fibrosis), birth injuries, cerebral palsy. Also, children who often suffer from infectious diseases (ARI, intestinal infections) may be prone to the development of malnutrition.

External causes do not depend on the state of health of the child, but are caused by an environment unfavorable for development, incorrect actions of parents:

• inadequate feeding (breast milk or formula);
• improper grip of the nipple during breastfeeding and, as a result, a lack of milk;
• poor nutrition of a nursing mother;
• unbalanced diet;
• too low-calorie food;
• late introduction of complementary foods;
• excess of the norm of taken vitamins (especially A and D);
• taking certain medications;
• poisoning;
• lack of parental attention, walks in the fresh air;
• lack of activities with the child in the form of massage and gymnastics, rare bathing, poor sleep.

Diagnostics

Suspecting malnutrition, the pediatrician will diagnose and prescribe a series of tests. So, the baby will be examined to determine the condition of his skin, nails and hair, muscle tone, thickness of the subcutaneous fat layer. The doctor will interview the parents about the child's usual condition: how he eats, sleeps, behaves, how he is looked after. The congenital diseases discussed above will be important: their presence can help confirm the diagnosis of the child.

In addition, it will be necessary to pass tests and undergo research:

• general urine and blood tests;
• stool analysis;
• blood chemistry;
• Ultrasound of the abdominal organs;
• examination of the heart using an electrocardiogram, echocardiography;
• electroencephalogram - examination of the brain.

You may also need to consult a number of pediatric doctors of a narrow profile: a neurologist, a cardiologist, a gastroenterologist, a geneticist, etc.

Treatment of malnutrition in children

When establishing an accurate diagnosis, the doctor will prescribe treatment, which includes:

• elimination of the cause that caused malnutrition;
• establishing proper nutrition of the child, following a certain diet;
• ensuring proper care from parents;
• drug therapy (vitamins, immunomodulators, probiotics, drugs to improve the production of stomach enzymes);
• massage, ultraviolet irradiation can be prescribed.

The diet for this diagnosis is as follows:

1. At first, for 2 days to 2 weeks, the baby is fed food intended for younger babies. The calculated norm of food is divided into 9-10 receptions.
2. Then the food is brought to the age norm according to the weight of the patient, special mixtures are added.
3. The next stage includes an increase in the calorie content of food consumed, nutrition should be enhanced.

As for intrauterine pathology, for treatment, first of all, breastfeeding is established so that the baby receives enough nutrients, and they also monitor his body temperature and maintain it at the right level.

Lifestyle of children with malnutrition

When diagnosing this disease or suspecting its occurrence due to some factors, you need to adhere to a certain lifestyle. In addition to a balanced diet with sufficient (and sometimes increased) calories, the necessary amount of vitamins and microelements, the parents of such a child must provide him with the necessary care and adherence to the daily routine: daily walks (at least 3 hours), therapeutic massage, gymnastics, nightly bathing.

The prevention of pathology is of great importance. And it should begin even before the birth of the child,. A pregnant woman should eat properly, fully and balanced, follow the doctor's prescriptions regarding the use of vitamin complexes. After the baby is born, you need to monitor his nutrition, be sure to try to establish breastfeeding, which provides him with everything necessary for normal growth and development.

It is necessary to monitor the height and weight of the child, visit a pediatrician to monitor these indicators and regular examinations of the baby. After 6 months, complementary foods must be introduced into the child's diet in accordance with the standards and recommendations of the WHO. The baby's diet should include a variety of healthy foods: cereals, meat, vegetables and fruits, dairy and sour-milk products.

How to recognize malnutrition

Parents should closely monitor the condition of their child and notice all changes in his behavior, eating and other habits, and general condition.

Disturbance of appetite and sleep, too much weight loss, skin problems, lethargy and apathy - all these signs should alert.

If you suspect an insufficient set of weight and height, you must definitely show the child to the pediatrician. Do not ignore monthly trips to the clinic for weighing and examination: this is how a doctor with many years of experience will be able to recognize an incipient disease that young parents may miss.

Video: complementary foods and norms for the growth and weight of a child as part of the prevention and diagnosis of malnutrition

Proper nutrition of the child plays a very important role in the process of his growth and development. Therefore, for the prevention of malnutrition, it will be useful to learn the basic rules for introducing complementary foods for the smallest, which in the future will provide the basis for proper eating habits.

Also pay attention to this short video, which clearly demonstrates the norms of height and weight of babies depending on age. Such data will also help you find out if everything is in order with the child, and also not to panic too much if your child does not fall into the standard parameters of hospital tables.

It is very important to observe the normal development of your baby from its very birth, so as not to miss the alarming bells of the onset of any disease. Knowing more about such a pathology as malnutrition, you will carefully consider his condition and provide the baby with proper care and proper diet. If you had to face such an unpleasant problem, please share your experience in the comments. Tell us what doctors advised and prescribed for you, how you coped with the disease. And may your children always be healthy!

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Introduction

From birth, the child begins to significantly gain in body weight, all his organs grow, including the bones of the skeleton. If the baby is not properly fed and cared for, the first signs of malnutrition will immediately begin to appear in the form of a disruption in the functioning of various organs and systems. Most often, malnutrition develops due to a lack of protein and calories in the diet. With the initial lag in body weight, disturbances from the gastrointestinal tract begin, which leads to a violation of the absorption of nutrients. As a rule, children also suffer from a lack of vitamins and trace elements in their diet.

Causes of malnutrition

Internal factors include diseases of various internal organs involved in digestion, that is, nutrients, under the influence of any reasons, cannot be absorbed by the body. Here, for example, it is appropriate to say that the violation can be both at the level of the gastrointestinal tract, and at the tissue and cellular level. In this case, various metabolic disorders occur in the cell itself. Cellular energy reserves gradually decrease. In the case of their complete depletion, the natural process of cell death begins.

Internal causes of malnutrition

• Encephalopathy that occurs in the fetus during pregnancy. Here we are talking about the fact that during the period of intrauterine development in the fetus, the normal activity of the central nervous system is disturbed, with a secondary disruption of the work of all internal organs and systems.
• Underdevelopment of lung tissue. Insufficient oxygen enrichment of the blood leads to metabolic disorders in the body, and slows down the development of organs and systems.
• Congenital pathology of the gastrointestinal tract - when such phenomena as constipation or vomiting are constantly present (with Hirschsprung's disease, dolichosigma, impaired location of the pancreas).
• Frequent abdominal operations that lead to "short bowel" syndrome. The natural physiological process of food digestion is disturbed.
• Hereditary diseases of the immune system, leading to a decrease in the body's defenses, inability to fight infection.
• Some endocrine diseases. Hypothyroidism is a disease of the thyroid gland, in which growth and metabolic processes in the body slow down. Pituitary dwarfism is a disease of the central organ of the endocrine system, as a result of which a sufficient amount of growth hormone is not produced.
• Metabolic diseases that are inherited. For example, galactosemia (intolerance to milk and dairy products), fructosemia is a similar disease in which the child's body does not absorb the fructose contained in vegetables and fruits. Rarer hereditary pathologies related to metabolic disorders include: leucinosis, Niemann-Pick disease, Tay-Sachs and others.

External causes of malnutrition

• Firstly, the quantitative underfeeding of the baby occurs due to the underdevelopment of the female breast (flat nipple, inverted nipple) or lack of female milk. On the part of the child, the cause may be: an underdeveloped lower jaw, constant vomiting, a short frenulum at the lower edge of the tongue.
• Secondly, insufficient feeding of the mother with high-quality breast milk, or improper use of the nutrient mixture, late introduction of supplementary feeding or complementary foods to the child, insufficient intake of all the necessary and useful ingredients in the baby's diet also leads to chronic malnutrition and the development of malnutrition.

Clinical signs and symptoms of malnutrition by degree

With malnutrition, there are several main syndromes:
1. The first of these is a syndrome in which the trophic function of organs and tissues is disturbed. Here we are talking about the fact that metabolic processes in the organs and tissues of the body slow down, body weight drops, the subcutaneous fat layer becomes much thinner, the skin becomes lethargic and flabby.
2. Another important syndrome is a syndrome in which there is a violation of digestive functions. The entire digestive tract is affected. Less hydrochloric acid and pepsin are produced in the stomach, and there are not enough enzymes in the intestines to process the food bolus.
The main symptoms of the syndrome of digestive disorders are:

• stool disorder, which can manifest itself both in the form of constipation and diarrhea;
• the chair becomes unformed, shines;
• with a more detailed examination of the stool, I find in it undigested food residues.

In each individual case, more than one of the above syndromes may be expressed. The manifestations of malnutrition also depend on the predominance of the lack of any component of food. For example, during protein starvation, symptoms of hematopoiesis and a decrease in the body's defenses prevail.

There are three degrees of malnutrition. This separation is necessary for the convenience of assessing the general condition of the child and for planning the amount of treatment. But in reality, the degrees of malnutrition are stages of the same process, following one after another.

Hypotrophy of the first degree

Initially, fat reserves disappear in the abdomen, then in other places. The degree of depletion of the subcutaneous fat layer is assessed by different methods. The most practical, and at the same time informative method, is the Chulitskaya index. This method is based on measuring the circumference of the shoulder in two different places, then the hips and lower legs, and the child's height is subtracted from the resulting amount. The norm for a child up to a year is 20-25 cm. Another method is to measure the skin fold in four different places: on the abdomen to the left of the navel, on the shoulder, in the area of ​​​​the shoulder blades, and finally, on the thigh from the outside. With normal growth and development of the child, the skin fold is approximately 2-2.5 cm. In the first degree of malnutrition, the Chulitskaya index is 10-15 centimeters, and the skin fold slightly decreases.

Symptoms of hypotrophy of the first degree:

• Fat folds are flabby, muscle tone is reduced, elasticity and firmness of the skin is lost.
• The growth of the child initially corresponds to age norms.
• Body weight is reduced from approximately 11% to 20% of the original.
• General health is normal. There is rapid fatigue.
• There are no disorders of the central nervous system. Sleep disturbing, intermittent.
• The child is a little irritable, may spit up the food he has eaten.

Hypotrophy of the second degree

Signs of malnutrition of the second degree:

• The subcutaneous fat layer is very thin on the legs, arms, and may be absent on the abdomen or chest.
• The Chulitskaya index decreases, and varies from one to ten centimeters.
• The skin is pale, dry.
• The skin is flabby, easily shifts into folds.
• Hair and nails become brittle.
• Muscle mass on the limbs decreases, body weight decreases by about twenty to thirty percent, and stunting is also noted.
• Thermoregulation is disturbed, such children quickly freeze, or also quickly overheat.
• There is a high risk of exacerbation of chronic infections (pyelonephritis, otitis media, pneumonia).
• Violation of resistance to the food taken. In connection with trophic disorders of the villi and the intestinal mucosa, digestion is disturbed, in particular the absorption of nutrients. Dysbacteriosis appears, that is, pathogenic bacterial flora predominates. Children appear: increased gas formation, bloating and discomfort in the abdomen. Frequent constipation or diarrhea, often alternating one after another.
• Decreased muscle tone. Due to the significantly reduced muscle tone, the abdomen protrudes outward, and the impression of a frog's abdomen is created.
• The lack of vitamin D and calcium in the body leads to additional development of muscle weakness, the development of symptoms of osteoporosis (washing out of calcium from the bones). At the same time, the bones of the skull become soft, the large and small fontanelles remain open for quite a long time.
• On the part of the central nervous system, a number of pathological disorders similar to those in the first degree of malnutrition are also revealed. Children are restless, cannot fall asleep, often act up. Then the characteristic symptoms of overexcitation of the central nervous system are gradually replaced by lethargy and apathy towards the outside world.

Hypotrophy of the third degree

Characteristic signs and symptoms of hypotrophy of the third degree:

• By appearance, you can immediately determine that there is a chronic lack of nutrition. The subcutaneous fat layer is absent in almost all places, including the face. The skin is dry, pale and so thin that the child looks like a mummy.
• When you try to form a skin fold with your fingers, there is practically no resistance of healthy skin. The elasticity of the skin is so reduced that the fold does not straighten out for a long time after releasing the fingers. Deep wrinkles form all over the body.
• Muscle mass and body weight as a whole are so small that the fatness index according to Chulitskaya is not determined, or is negative. The overall weight loss is 30% or more of normal values.
• On the face, the retraction of the cheeks is visible, the cheekbones protrude forward, the sharpening of the chin is pronounced.
• Manifestations of lack of vital trace elements and vitamins are clearly expressed.
• Lack of iron affects the appearance of cracks in the corners of the mouth (jamming), as well as anemia.
• The lack of vitamins A and C manifests itself in the form of appearance on the mucous membranes: bleeding and atrophy (death, reduction in size) of the gums, stomatitis in the form of small whitish rashes.
• The abdomen is greatly distended due to the weakness of the muscles that support it.
• Body temperature often jumps up and down due to the fact that the thermoregulation center in the brain does not work.
• Immunity is sharply reduced. You can detect signs of sluggish chronic infections. Inflammation of the middle ear - otitis, inflammation of the kidneys - pyelonephritis, pneumonia - pneumonia.
• The child's growth lags behind the average.

Options for the course of malnutrition

Depending on the period of development of hypotrophic manifestations, there are four variants of the course of hypotrophy:

• intrauterine malnutrition;
• hypostatura;
• alimentary insanity.

Intrauterine malnutrition

There are several options for the development of intrauterine malnutrition:
1. Hypotrophic- when the nutrition of all organs and systems is disturbed, the fetus develops very slowly, and does not correspond to the gestational age.
2. Hypoplastic- this variant of development means that along with insufficient general development of the fetal organism, there is also some lag in the maturation and development of all organs. Here we are talking about the fact that organs and tissues at birth are not sufficiently formed, and do not fully perform their functions.
3. Dysplastic the variant of the course of malnutrition is characterized by uneven development of individual organs. Some, such as the heart, liver, develop normally, corresponding to the gestational age, while others, on the contrary, lag behind in their development, or develop asymmetrically.

Hypostatura

The only difference from true malnutrition is that the skin and subcutaneous fat layer do not undergo strong changes.

Hypostatura, as one of the variants of the course of malnutrition, occurs secondarily in chronic diseases of some internal organs. The development of hypostature is usually associated with transitional periods of growth and development of the child. One of these periods falls on the first six months of a child's life. At the same time, they begin to gradually add food products, milk formulas to mother's milk - in other words, to supplement the child. The appearance of this pathology in the second year of life is associated primarily with congenital chronic diseases. Here are the most common ones:

• Congenital malformations of the cardiovascular system. Violation of blood circulation leads to insufficient flow of oxygen and nutrients to organs and tissues.
• Encephalopathies in combination with endocrine disorders also have an extremely adverse effect on the metabolism in the body, delaying development and growth.
• Bronchopulmonary dysplasia is a disturbed development of the lung tissue during the period of intrauterine development of the fetus. In this case, there are serious complications associated with breathing and the delivery of oxygen to the blood.

Kwashiorkor

In addition, there are specific disorders in which the body receives less, does not synthesize or does not absorb protein foods at all.

Disorders that contribute to the development of kwashiorkor include:

• Long-term indigestion, manifested by persistent unstable stools - in other words, the child has chronic diarrhea.
• In diseases of the liver, its protein-forming function is disrupted.
• Kidney disease, accompanied by increased loss of protein along with urine.
• Burns, excessive blood loss, infectious diseases.

In addition to the constant symptoms, children with kwashiorkor have other signs of the disease that occur with varying frequency.

Common symptoms are:
1. Color change, softening of thinning and, eventually, hair loss on the head. Hair becomes lighter, and in later manifestations of the disease, or in older children, discolored or even gray strands of hair are found.
2. Dermatitis is an inflammation of the superficial layers of the skin. Redness, itching, cracks appear on the skin. Subsequently, the skin in the affected areas exfoliates, and traces remain in this place in the form of light spots.

Rare symptoms include:
1. Dermatosis - red-brown spots of a rounded shape.
2. Hepatomegaly is an abnormal enlargement of the liver. The liver tissue is replaced by adipose and connective tissue. The liver is not able to form enzymes and other active substances necessary for the normal function of the whole organism.
3. Kidney dysfunction. The filtration capacity is reduced. In the blood, harmful metabolic products accumulate.
4. Stool disorders are permanent. The child has persistent diarrhea. The feces are shiny and smell unpleasant.

Summing up the material presented, we can say with confidence that kwashiorkor is a disease that is extremely rare in countries with a temperate climate. Countries located in this geographic latitude have a developed social status and standard of living, so the possibility of malnutrition and a deficiency in the diet of proteins and calories is practically excluded.

Alimentary insanity

To establish the cause and make an accurate diagnosis, find out:

• From the history of the onset of the disease, they learn what the body weight of the child was even before the first signs of malnutrition appeared.
• The socio-economic situation in which the child's family is located.
• If possible, find out the daily diet.
• Whether there is vomiting or chronic diarrhea, and how often it occurs.
• Is this child taking any medications? For example, anorexigenic, which suppress appetite, or diuretics, which remove many useful nutrients from the body, including protein.
• Are there any disorders of the central nervous system: stressful situations, alcohol or drug addiction.
• In adolescence, in particular in girls, starting from the age of 12, they find out the presence and evaluate the regularity, frequency and duration of the menstrual cycle.

Among all the symptoms that appear with alimentary insanity, permanent and rare symptoms are distinguished.

Permanent symptoms include:

• weight loss reaches up to 60% of normal, age-appropriate;
• decrease in the thickness of the subcutaneous fat layer;
• reduction in the mass of muscle fibers;
• the limbs of the patient become very thin;
• many wrinkles appear on the face, the skin fits all the facial bones and it seems as if this is the face of an old man.

• Diarrhea is chronic. The chair is liquid, shines, with an unpleasant smell.
• Thinning and clarification of hair, which eventually begin to fall out.
• Exacerbation of chronic infections is a very frequent companion of an organism weakened by malnutrition.
• Thrush is a fungal disease that affects the mucous membranes of the mouth, vagina and urethra. They are manifested by whitish discharge, itching and discomfort in these places.
• Symptoms of multivitamin deficiency, depending on the lack of certain vitamins and minerals.

• Eye changes are manifested by inflammation of the eyelids, the formation of new small vessels on the cornea. Grayish plaques appear in the inner corners of the eyes (lack of vitamin A).
• In the oral cavity, inflammatory changes in the mucous membrane and gums are observed. The tongue increases in size (due to a lack of vitamin B 12).
• The heart is enlarged. Insufficient strength of cardiac impulses leads to stagnation of blood in the veins, swelling of the lower extremities appears.
• Weakness of the muscles of the anterior abdominal wall causes a sagging, protruding abdomen. The liver protrudes beyond the lower edge of the right hypochondrium.
• Explicit neurological disorders are manifested in nervousness, increased irritability, muscle weakness, and a decrease in tendon reflexes.

• Memory worsens, mental and cognitive abilities, including working capacity, decrease.
• Decreased visual acuity. A lack of vitamin A causes a decrease in vision at dusk.
• The sharpness of taste sensations is also reduced.
• A lack of vitamin C leads to increased capillary fragility. Small punctate hemorrhages can be seen on the skin after a slight pinch.

Lack of essential fatty acids

In most cases, this variant of malnutrition appears in infants who lack the nutrition of mother's milk. Cow's milk and other milk mixtures do not contain essential fatty acids in the amount necessary for the energy and plastic costs of a young organism. Depending on the deficiency of one or another fatty acid, the symptoms of the disease will differ slightly from each other.

With a lack of linoleic acid, the following symptoms appear:

• Dryness of the skin with exfoliation of the superficial stratum corneum.
• Wound healing continues for a long period.
• Thrombocytopenia - a reduced number of platelets (blood cells responsible for its clotting) in the blood. The lack of platelets leads to increased fragility of small vessels, with accidental minor domestic injuries of the skin, bleeding lengthens. Insignificant tweaks cause the appearance of many small-point hemorrhages.
• Prolonged loose stools (diarrhea).
• Periodic exacerbations of infectious diseases (for example, skin or lungs).

• numbness and paresthesia (tingling sensation) of the lower and upper extremities;
• general muscle weakness;
• visual impairment.

Diagnosis of malnutrition

Key points

Detection of important clinical signs in all major systems involved in the pathological process. This includes the following violations:

• fatness disorders - manifested in the form of thinning of the subcutaneous fat layer and trophic changes;
• digestive disorders - include changes in food resistance;
• metabolic disorders: protein, fat, carbohydrate, mineral, vitamin;
• functional disorders of the central nervous system.

The second point that should not escape the attention of doctors is the differentiation of pathological changes that occur during malnutrition, with other similar diseases, with a decrease in height, body weight, and overall physical development of children.

Symptoms of children with hypostatura are very similar to a disease such as nanism. This is a pathology of the central endocrine organs (hypothalamus and pituitary gland), in which growth hormone, somatotropin, is not produced. With this disease, unlike hypostatura, there are no pathological changes in the form of thinning of the subcutaneous fat layer and other trophic disorders. All organs develop evenly, although they are reduced in size.

Assessment of the child's condition and determination of the degree of pathological changes is also determined by the nature of the feces. Initially, with malnutrition, the stool is scanty, colorless, with a characteristic fetid odor. In the future, violations of the functional ability to process food through the gastrointestinal tract lead to the fact that the stool becomes plentiful, shiny, it contains the remains of undigested food, muscle fibers. Infection with pathogenic bacteria of the intestinal mucosa entails dysbacteriosis (diarrhea, bloating and discomfort in the abdomen).

Due to insufficient intake of protein, the body uses internal reserves (from muscles, adipose tissue), the metabolic products of which are excreted by the kidneys in the form of ammonia. The urine of such patients has the smell of ammonia.

Laboratory research

In biochemical analyzes, signs of impaired liver function, lack of vitamins and trace elements can be detected.

Instrumental diagnostic methods

Ultrasound is used when the borders of the heart are enlarged, the liver is enlarged, or there are other pathological changes in the abdominal cavity.
If necessary, or in doubtful cases, the attending physician prescribes the appropriate instrumental diagnostic method at his discretion.
Diagnosis of malnutrition and the degree of pathological changes is not an easy task, and requires a lot of patience, care and experience from the doctor.

Hypotrophy treatment

Complex therapy includes:

• Determination of the cause that caused malnutrition, simultaneously with an attempt to regulate and eliminate it.
• Diet therapy, which is selected individually in each specific case, and also depends on the degree of pathological disorders in the body.
• Detection of chronic foci of infection that contribute to the development of malnutrition, as well as their active treatment.
• Symptomatic treatment, which includes the use of multivitamin and enzyme preparations.
• Appropriate regimen with proper care and educational activities.
• Periodic courses of massage and therapeutic exercises.

diet therapy

• 2/3 for hypotrophics of the first degree.
• 1/2 for hypotrophics of the second degree.
• 1/3 for hypotrophics of the third degree.

3. The third period in diet therapy is the stage of enhanced food intake. Only after complete restoration of the functional activity of the gastrointestinal tract, the patient can increase the load of food.
In the third period, intensive feeding is continued, however, with a restriction of protein intake, since the increased intake of protein products is not fully absorbed by the body.
During each stage of diet therapy, the stool is periodically checked for the content of residual dietary fiber and fat (coprogram).

Other, no less important conditions when prescribing a diet are:
1. Reducing the periods between feedings. And the frequency of feeding itself increases several times a day, and is:

• with hypotrophy of the first degree - seven times a day;
• in the second degree - eight times a day;
• in the third degree - ten times a day.

3. Maintaining adequate periodic nutritional control. For this purpose, special diaries are kept, where the amount of food eaten is noted. Systematic control is simultaneously performed for stool, diuresis (number and frequency of urination). If nutrient mixtures are administered intravenously, then their amount is also recorded in the diary.

4. Fecal samples are taken several times a week for the presence of undigested dietary fiber and fatty inclusions.

5. Every week, the child is weighed, and additional calculations are made to calculate the required amount of nutrients (proteins, fats and carbohydrates).

The criteria for the effectiveness of dietary therapy are:

• normalization of the condition and elasticity of the skin;
• improving the appetite and emotional state of the child;
• daily weight gain, an average of 25-30 grams.

Care of patients with malnutrition

• The conditions for staying in the wards should be as comfortable as possible, and are as follows: the lighting complied with all regulatory standards, airing was carried out twice a day, the air temperature was optimal, within 24-25 degrees Celsius.
• Daily walks in the fresh air serve both as hardening and as a prevention of upper respiratory tract infections (congestive pneumonia).
• Periodic gymnastic exercises and massage courses will help restore reduced muscle tone, and will have a beneficial effect on the general condition of the body.

Enzyme therapy

vitamin therapy

Stimulant Therapy

Symptomatic treatment

• With anemia, iron preparations (sorbifer, totem) are prescribed. If a child has a very low hemoglobin value (below 70 g/l), he is prescribed a red blood cell transfusion.
• With rickets, vitamin D is prescribed, as well as preventive courses of physiotherapy. For this purpose, irradiation with ultraviolet rays using a special quartz lamp is used.

Prevention of the development of malnutrition

• The child must be completely healthy.
• Eat food according to the age of the child.
• Complementary foods are introduced gradually, and before breastfeeding. The child eats with a small spoon.
• The change of one type of feeding is replaced by one type of complementary foods.
• The food you eat should be rich in vitamins and essential minerals.

Summing up the above material, it should be noted that the prognosis for the development of malnutrition depends primarily on the causes that participated in the occurrence of this pathological condition. The conditions of the external and internal environment, the nature of feeding, as well as the age of the patient - all this plays a big role in the development of malnutrition. With alimentary insufficiency, the outcome of the disease is usually favorable.

It is extremely common to observe malnutrition in children, accompanied by a slight increase in body weight in relation to height and age. When this gap exceeds 10%, hypotrophy is diagnosed.

Hypotrophy (protein-energy malnutrition (PEM)) is a spectrum of conditions caused by various levels of protein and calorie deficiency and is characterized by insufficient body weight in relation to height.

Hypostatura is described as one of the variants of PEI, in which an interconnected deficit is established, both in body weight and in height.

The causes of malnutrition can be divided into two groups:

• exogenous (associated with external factors);
• endogenous (internal causes).

The mechanism of the onset of the disease and the development of its manifestations (pathogenesis)

In pathogenesis, the following pathophysiological phases are distinguished:

1. 1st phase - hungry excitement. The consumption of reserve reserves of carbohydrates provides the body's energy needs, the metabolism of amino acids weakens, and the excretion of nitrogen decreases.
2. 2nd phase - the phase in which the metabolism switches to the breakdown of fat, the basal metabolism decreases, the synthesis of vital proteins is still preserved due to the breakdown of other body proteins.
3. The 3rd phase is irreversible: the splitting of the “internal” protein is carried out to cover energy goals, changes occur in the structure of mitochondria (organelles that are the energy base of cells) with a violation of their regulatory mechanisms.

Symptoms

Clinical manifestations of malnutrition are grouped into several syndromes.

Trophic disorder syndrome

Lack of tissue nutrition, which caused structural changes in tissues and cell death:

• flat or negative curve of body weight in dynamics;
• deficiency of body weight, to a lesser extent - body length;
• the proportionality of the physique is violated;
• trophic disorders of the skin and skin appendages: decreased elasticity, flabbiness, dryness, with cachexia (extreme exhaustion of the body) - a symptom of a "pouch" (a narrow mouth opening with deep wrinkles around it), dull nature of nails and hair, alopecia (baldness);
• the subcutaneous fat layer is consistently thinning - on the body, abdomen, limbs, face;
• muscle hypotorphy and increasing;
• decrease in tissue elasticity.

Syndrome of digestive disorders and impaired food tolerance

• appetite decreases up to anorexia;
• increasing dyspeptic disorders - regurgitation, unstable stools, irregular defecation, alternating;
• enzymatic and secretory gastrointestinal tract are weakened.

CNS dysfunction syndrome

• disturbed emotional tone (scream, cry) and neuro-reflex excitability;
• involuntary muscle contraction;
• hyporeflexia (decreased reflexes);
• lag of psycho-emotional development;
• thermoregulation and sleep are disturbed.

Syndrome of impaired hematopoiesis and immunobiological reactivity

• deficiency of iron and other micro and macro elements, vitamins (iron deficiency anemia, rickets, etc.);
• frequent infectious and inflammatory diseases, their course is erased and atypical;
• develop toxic-septic conditions, dysbiocenosis of natural microbiological niches;
• signs of secondary immunodeficiency.

Weakened nonspecific resistance.

Depending on the deficiency of body weight, three degrees of malnutrition are distinguished: at degree 1, the insufficiency is 11–20% of the due value, at degree 2 - 21–30%, at degree 3 - a deficiency of more than 30% of the due body weight. In clinical practice, malnutrition of the 1st degree prevails, mainly associated with temporary alimentary disorders, less often the 2nd degree is observed, the development of which is associated with a complex of etiological factors, mainly endogenous. III degree or cachexia with irreversible organ system consequences and subsequent death is a rare condition.

Fetal hypotraphy

Fetal hypotrophy is a delay in intrauterine development of the child.

There are three options for the development of pathology:

1. Hypotrophic. There is a malnutrition of all systems and organs, characterized by slow development of the fetus, which does not correspond to the gestational age.
2. Hypoplastic. It is characterized by a delay in the maturation of all organs in combination with a lag in the overall development of the fetus. This means that at birth, tissues and organs are not sufficiently formed and their functions are not fully performed.
3. Dysplastic. There is uneven development of some organs. For example, the liver, heart develop in accordance with the gestational age, and other organs have a lag in maturation.

Diagnosis of malnutrition in children

Diagnosis is based on anthropometric data (a method of measuring the human body and its parts): a lack of body weight and a slowdown in growth rates relative to proper values.

In the blood test, anemia is detected, with malnutrition of the 3rd degree - absolute lymphopenia (decrease in lymphocytes), slowing down the ESR.

Biochemical examination reveals:

• hypoalbuminemia (decrease in albumin, a substance that is an integral part of blood plasma);
• dysproteinemia (imbalance between blood protein fractions);
• hypoglycemia (decrease in glucose concentration);
• hypocholesterolemia (decrease in cholesterol);
• dyslipilemia (impaired lipid balance).

In the analysis of urine - leukocyturia, ketone bodies, an excess amount of ammonia. B - signs of impaired intestinal digestion.

How is the treatment carried out?

Children with grade 1 malnutrition are treated on an outpatient basis when the social environment is favorable. At the 2nd - 3rd degree, therapy is carried out only in a hospital (first in the intensive care unit, then in the general somatic unit).

All children need a therapeutic and protective regime: sufficient sleep in calm conditions, regular ventilation of the room, access to sunlight, wet cleaning twice a day. The temperature in the room is maintained at 25 - 26 ° C. Walks, therapeutic exercises, massage, bathing - daily; skin and visible mucous membranes are carefully cared for (moisturizing creams, emulsions, vitamin masks).

Diet therapy is the basis of treatment, and is carried out in 3 stages. It is based on the rejuvenation of the diet (“step back”), that is, they use foods that are typical for an earlier age group.

When a child is breastfed, it is unacceptable to exclude a single drop of mother's milk from the diet of a patient with malnutrition.

Organization of diet therapy

In the complex treatment of children, enzyme replacement therapy is used, taking into account the coprogram, as well as vitamin D3, iron preparations, vitamins of groups B, C, PP, A and E. Probiotic preparations based on bifido- and lactobacilli are prescribed to correct microbiocenosis disorders. At the 3rd degree of malnutrition, antimycotic agents are used to prevent candidal lesions of the intestine.

The use of anabolic drugs is carried out with caution, since, under the condition of a deficiency of nutrients, their use can lead to profound disorders of protein and other types of metabolism.

Conclusion

The prognosis is favorable for PEU of the 1st and 2nd degree. With the 3rd degree of malnutrition, despite the ongoing treatment, mortality is 20 - 50% of cases.

- chronic malnutrition, accompanied by an insufficient increase in body weight of the child in relation to his height and age. Hypotrophy in children is expressed by a child's lag in weight, growth retardation, lag in psychomotor development, underdevelopment of the subcutaneous fat layer, and a decrease in skin turgor. Diagnosis of malnutrition in children is based on examination data and analysis of anthropometric indicators of the child's physical development. Treatment of malnutrition in children involves changing the regimen, diet and caloric intake of the child and the nursing mother; if necessary, parenteral correction of metabolic disorders.

General information

Hypotrophy in children is a lack of body weight due to a violation of assimilation or insufficient intake of nutrients in the child's body. In pediatrics, malnutrition, paratrophy and hypostatura are considered as independent types of chronic eating disorders in children - dystrophy. Hypotrophy is the most common and significant variant of dystrophy, to which children of the first 3 years of life are especially susceptible. The prevalence of malnutrition in children in different countries of the world, depending on the level of their socio-economic development, ranges from 2-7 to 30%.

Hypotrophy in a child is said to be when the body weight lags by more than 10% compared to the age norm. Hypotrophy in children is accompanied by serious disturbances in metabolic processes, decreased immunity, and a lag in psychomotor and speech development.

Causes of malnutrition in children

A variety of prenatal and postnatal factors can lead to chronic malnutrition.

Intrauterine malnutrition in children is associated with adverse conditions that disrupt the normal development of the fetus. In the prenatal period, pathology of pregnancy (toxicosis, preeclampsia, fetoplacental insufficiency, premature birth), somatic diseases of the pregnant woman (diabetes mellitus, nephropathy, pyelonephritis, heart defects, hypertension, etc.), nervous stress, bad habits, malnutrition of women, industrial and environmental hazards, intrauterine infection and fetal hypoxia.

Extrauterine malnutrition in young children may be due to endogenous and exogenous causes. The causes of the endogenous order include chromosomal abnormalities and congenital malformations, fermentopathy (celiac disease, disaccharidase lactase deficiency, malabsorption syndrome, etc.), immunodeficiency states, constitutional abnormalities (diathesis).

Exogenous factors leading to malnutrition in children are divided into alimentary, infectious and social. Alimentary influences are associated with protein-energy deficiency due to insufficient or unbalanced nutrition. Hypotrophy in a child may be the result of constant underfeeding associated with difficulty sucking with an irregular shape of the mother's nipples (flat or inverted nipples), hypogalactia, insufficient amount of milk formula, profuse regurgitation, qualitatively malnutrition (microelement deficiency), poor nutrition of a nursing mother, etc. The same group of reasons should include diseases of the newborn itself, which do not allow him to actively suck and receive the necessary amount of food: cleft lip and palate (cleft lip, cleft palate), congenital heart defects, birth trauma, perinatal encephalopathy, pyloric stenosis, cerebral palsy, alcohol fetal syndrome etc.

Children suffering from frequent acute respiratory viral infections, intestinal infections, pneumonia, tuberculosis, etc. are prone to the development of acquired malnutrition. An important role in the occurrence of malnutrition in children belongs to unfavorable sanitary and hygienic conditions - poor child care, insufficient exposure to fresh air, rare bathing, insufficient sleep .

Classification of malnutrition in children

Thus, according to the time of occurrence, intrauterine (prenatal, congenital), postnatal (acquired) and mixed malnutrition in children are distinguished. The development of congenital malnutrition is based on a violation of the uteroplacental circulation, fetal hypoxia and, as a result, a violation of trophic processes leading to intrauterine growth retardation. In the pathogenesis of acquired malnutrition in children, the leading role belongs to protein-energy deficiency due to malnutrition, impaired digestion of food or absorption of nutrients. At the same time, the energy costs of a growing organism are not compensated by food coming from outside. With a mixed form of malnutrition in children, alimentary, infectious or social influences join the adverse factors that acted in the prenatal period after birth.

According to the severity of underweight in children, hypotrophy of I (mild), II (medium) and III (severe) degrees is distinguished. Hypotrophy of the 1st degree is said when a child lags behind in weight by 10-20% of the age norm with normal growth. Hypotrophy of the II degree in children is characterized by a decrease in weight by 20-30% and a growth lag of 2-3 cm. With hypotrophy of the III degree, the body weight deficit exceeds 30% of the due age, there is a significant lag in growth.

During malnutrition in children, the initial period, the stages of progression, stabilization and convalescence are distinguished.

Symptoms of malnutrition in children

With malnutrition of the first degree, the condition of the children is satisfactory; neuropsychic development corresponds to age; there may be a mild decrease in appetite. A close examination reveals pallor of the skin, a decrease in tissue turgor, thinning of the thickness of the subcutaneous fat layer on the abdomen.

Hypotrophy of the II degree in children is accompanied by a violation of the child's activity (excitation or lethargy, lag in motor development), poor appetite. The skin is pale, scaly, flabby. There is a decrease in muscle tone, elasticity and tissue turgor. The skin easily gathers into folds, which are then poorly straightened. The subcutaneous fat layer disappears on the abdomen, trunk and limbs; on the face - saved. Children often present with shortness of breath, hypotension, and tachycardia. Children with II degree malnutrition often suffer from intercurrent diseases - otitis media, pneumonia, pyelonephritis.

Hypotrophy III degree in children is characterized by a sharp depletion: the subcutaneous fat layer atrophies throughout the body and on the face. The child is lethargic, adynamic; practically does not react to stimuli (sound, light, pain); sharply lags behind in growth and neuropsychic development. The skin is pale gray, the mucous membranes are dry and pale; the muscle is atrophic, tissue turgor is completely lost. Exhaustion and dehydration lead to retraction of the eyeballs and fontanel, sharpening of facial features, the formation of cracks in the corners of the mouth, and impaired thermoregulation. Children are prone to regurgitation, vomiting, diarrhea, decreased urination. In children with stage III hypotrophy, conjunctivitis, candidal stomatitis (thrush), glossitis, alopecia, atelectasis in the lungs, congestive pneumonia, rickets, and anemia are often noted. In the terminal stage of malnutrition, children develop hypothermia, bradycardia, and hypoglycemia.

Diagnosis of malnutrition in children

Intrauterine fetal malnutrition, as a rule, is detected during ultrasound screening of pregnant women. In the process of obstetric ultrasound, the dimensions of the head, length and estimated weight of the fetus are determined. With a delay in intrauterine development of the fetus, the obstetrician-gynecologist sends the pregnant woman to the hospital to clarify the causes of malnutrition.

In newborns, the presence of malnutrition can be detected by a neonatologist immediately after birth. Acquired malnutrition is detected, a study of the coprogram and feces for dysbacteriosis, a biochemical blood test, etc.).

Treatment of malnutrition in children

Treatment of postnatal malnutrition of the 1st degree in children is carried out on an outpatient basis, malnutrition of the II and III degrees - in a hospital. The main measures include the elimination of the causes of malnutrition, diet therapy, the organization of proper care, and the correction of metabolic disorders.

Diet therapy for malnutrition in children is implemented in 2 stages: clarification of food tolerance (from 3-4 to 10-12 days) and a gradual increase in the volume and calorie content of food to the physiological age norm. The implementation of diet therapy for malnutrition in children is based on fractional frequent feeding of the child, weekly calculation of the food load, regular monitoring and correction of treatment. Feeding children with weakened sucking or swallowing reflexes is carried out through a probe.

Drug therapy for malnutrition in children includes the appointment of enzymes, vitamins, adaptogens, anabolic hormones. With severe malnutrition, children are given intravenous administration of protein hydrolysates, glucose, saline solutions, and vitamins. With malnutrition in children, massage with elements of exercise therapy, UVI is useful.

Forecast and prevention of malnutrition in children

With timely treatment of hypotrophy of I and II degrees, the prognosis for the life of children is favorable; with malnutrition III degree mortality reaches 30-50%. To prevent the progression of malnutrition and possible complications, children should be examined weekly by a pediatrician with anthropometry and nutrition correction.

Prevention of prenatal fetal malnutrition should include adherence to the regimen of the day and nutrition of the expectant mother, correction of the pathology of pregnancy, exclusion of the impact on the fetus of various adverse factors. After the birth of a child, the quality of nutrition of a nursing mother, the timely introduction of complementary foods, the control of the dynamics of an increase in the body weight of a child, the organization of rational care for a newborn, and the elimination of concomitant diseases in children become important.

Dystrophy(Greek dys - disorder, trophe - nutrition) develops mainly in young children and is characterized by impaired absorption of nutrients by body tissues. There are the following types of dystrophies: 1) dystrophy with a lack of body weight (hypotrophy); 2) dystrophy with body weight corresponding to height or some excess of mass over length (paratrophy); 3) dystrophy with overweight (obesity) (Table 1).

Hypotrophy(Greek hypo - under, below trophe - nutrition) - a chronic eating disorder with a lack of body weight. This is a pathophysiological reaction of a young child, accompanied by a violation of the metabolic and trophic functions of the body and characterized by a decrease in food tolerance and immunobiological reactivity. According to WHO, malnutrition (malnutrition) is diagnosed in 20-30% or more of young children.

Etiology: According to the time of occurrence, congenital (prenatal) and acquired (postnatal) malnutrition are distinguished (Table 1). The causes, clinic and treatment of intrauterine growth retardation are discussed above in the section "Antenatal malnutrition".

There are 2 groups of acquired malnutrition according to etiology - exogenous and endogenous (Table 1). With careful collection of anamnesis data, a mixed etiology of malnutrition in a child is often established. With exogenous causes, primary malnutrition is diagnosed, with endogenous causes - secondary (symptomatic).

Exogenous causes of malnutrition:

1. Nutritional factors- Quantitative underfeeding in case of hypogalactia in the mother or feeding difficulties on the part of the mother or child, or qualitative underfeeding (use of an age-inappropriate mixture, late introduction of complementary foods).

2. Infectious factors- intrauterine infections, infectious diseases of the gastrointestinal tract, repeated acute respiratory viral infections, sepsis.

3. Toxic factors- the use of low-quality milk mixtures with an expired shelf life, hypervitaminosis A and D, drug poisoning.

4. Disadvantages of care, regime, education.

Endogenous causes of malnutrition:

1. Perinatal encephalopathy of various origins.

2. Bronchopulmonary dysplasia.

3. Congenital malformations of the gastrointestinal tract, cardiovascular system, kidneys, liver, brain and spinal cord.

4. Primary malabsorption syndrome (deficiency of lactase, sucrose, maltase, cystic fibrosis, exudative enteropathy) or secondary (intolerance to cow's milk proteins, "short gut" syndrome after extensive bowel resections, secondary disaccharidase deficiency).

5. Hereditary immunodeficiency states.

6. Hereditary metabolic disorders.

7. Endocrine diseases (hypothyroidism, adrenogenital syndrome).

8. Anomalies of the constitution.

Pathogenesis:

With malnutrition, the utilization of nutrients (primarily proteins) is impaired both in the intestine and in tissues. In all patients, the excretion of nitrogenous products in the urine increases with a violation of the ratio between urea nitrogen and total urine nitrogen. A decrease in the enzymatic activity of the stomach, intestines, pancreas is characteristic, and the level of deficiency corresponds to the severity of malnutrition. Therefore, a nutritional load that is adequate for a healthy child can cause acute indigestion in a patient with II-III degree malnutrition. With malnutrition, the functions of the liver, heart, kidneys, lungs, immune, endocrine, and central nervous systems are disrupted.

Of the metabolic disorders, the most typical are: hypoproteinemia, hypoalbuminemia, aminoaciduria, a tendency to hypoglycemia, acidosis, hypokalemia and hypokalemia, hypocalcemia and hypophosphamenia.

Classification:

According to the severity, three degrees of malnutrition are distinguished: I, II, W: (Table 1). The diagnosis indicates the etiology, time of onset, period of the disease, comorbidity, complications. It is necessary to distinguish between primary and secondary (symptomatic) malnutrition. Primary malnutrition can be the main or concomitant diagnosis and is usually the result of undernutrition.

Secondary malnutrition- complication of the underlying disease. Diagnosis

malnutrition is competent in children up to 2-3 years of age.

Clinical picture:

All clinical symptoms of malnutrition in children for the following groups of syndromes:

1. Trophic_disorder syndrome- thinning of the subcutaneous fat layer, lack of body weight and disproportionate physique (Chulitskaya and Erisman indices are reduced), a flat curve of weight gain, trophic skin changes, muscle thinning, decreased tissue turgor, signs of polyhypovitaminosis.

2. Syndrome of reduced food tolerance- loss of appetite up to anorexia, development of dyspeptic disorders (regurgitation, vomiting, unstable stool), decrease in secretory and enzymatic functions of the gastrointestinal tract.

3. CNS dysfunction syndrome- violation of emotional tone and behavior; low activity, the predominance of negative emotions, sleep disturbance and thermoregulation, delayed psychomotor development, muscle hypo-, dystonia.

4. Syndrome of decreased immunobiological reactivity- a tendency to frequent infections - inflammatory diseases, their erased and atypical course, the development of toxic-septic conditions, dysbiocenoses, secondary immunodeficiency states, a decrease in nonspecific resistance.

Hypotrophy I degree characterized by thinning of the subcutaneous fat layer in all parts of the body and especially on the abdomen. The fatness index of Chulitskaya is reduced to 10-15. Tissue turgor and muscle tone are reduced, the fat fold is flabby. Characterized by pallor of the bones and mucous membranes, a decrease in firmness and elasticity of the skin. The growth of the child does not lag behind the norm. The body weight deficit is 10-20%. The weight gain curve is flattened. The child's health is not disturbed. Psychomotor development corresponds to age. The child is restless, does not sleep well. Immunological reactivity is not broken.

Hypotrophy II degree. The subcutaneous fat layer is absent on the abdomen, chest, sharply thinned on the limbs, preserved on the face. Severe pallor, dryness, decreased elasticity of the skin. The fatness index of Chulitskaya is 0-10. Reduced tissue turgor (a skin fold hangs down on the inner surface of the thighs) and muscle tone. Active rickets in children is manifested by muscle hypotension, symptoms of osteoporosis, osteomalacia and hypoplasia. The body weight deficit is 20-30% (in relation to height), there is a lag in growth. The body weight gain curve is flat. Appetite is reduced. Food tolerance is reduced. Often regurgitation and vomiting are observed. Characterized by weakness and irritability, the child is indifferent to the environment. Sleep is restless. The child loses already acquired motor skills and abilities. Thermoregulation is impaired, and the child quickly cools or overheats.

Most children develop various diseases (otitis media, pneumonia, pyelonephritis), which are asymptomatic and long-term.

The chair is unstable (often liquefied, undigested, rarely constipation). Significantly reduced acidity of gastric juice, secretion and activity of enzymes of the stomach, pancreas and intestines. Subcompensated intestinal dysbacteriosis develops.

Hypotrophy III degree(marasmus, atrophy). Primary malnutrition of the III degree is characterized by an extreme degree of exhaustion: the external child resembles a skeleton covered with skin. The subcutaneous fat layer is absent. The skin is pale gray, dry. Extremities are cold. Skin folds do not straighten out, as there is no elasticity of the skin. Characterized by thrush, stomatitis. The forehead is covered with wrinkles, the chin is pointed, the cheeks are sunken. The abdomen is distended, distended, or bowel loops are contoured. The chair is unstable.

Body temperature is often lowered. The patient quickly cools on examination, easily overheats. Against the background of a sharp decrease in immunological reactivity, various

foci of infection that are asymptomatic. Significantly reduced muscle mass. The weight gain curve is negative. The body weight deficit exceeds 30% in children of appropriate height. The Chulitskaya index is negative. The child is severely retarded. With secondary malnutrition of the III degree, the clinical picture is less severe than with primary ones, they are easier to treat if the underlying disease is identified and there is an opportunity to actively influence it.