Infantilism of the genital organs. Sexual infantilism: all about the causes and treatment of pathology

Infantilism of the uterus, or hypoplasia, is a pathology in which the female reproductive organ is delayed in its development.

That is, an adult woman has a uterus, the size and functionality of which corresponds to the uterus of a little girl or teenage girl. This condition can present certain difficulties in treatment, as well as in conception and gestation. Since the underdevelopment of the ovaries is usually present in the infantile uterus, the level of sex hormones in the woman's body is significantly lowered.

Causes of uterine infantilism

Often, the infantility of the uterus is caused by birth defects or a genetic predisposition. However, sometimes the development of this pathology is associated not with embryonic development, but with the impact on the body of a girl of various external factors:

hormonal failure - when the synthesis of estrogens in the body decreases, the uterus may stop developing;
mental deviations in a girl, frequent stress, emotional overload, depressive states;
lack of vitamins and other nutrients associated with poor and irregular nutrition;
physical overload associated with overly active sports;
frequent colds, infectious and viral diseases suffered in childhood;
toxic poisoning of the body, drug use;
the presence of endocrine diseases;
surgical interventions in the ovarian region.

Degrees of infantile uterus

In a healthy woman who does not have children, it should be seven to eight centimeters long (including the neck). If the uterus is infantile, its length may be significantly less. The degree of infantility of the uterus is determined depending on the causes that caused this pathological condition, as well as based on the size of the organ:

First degree (fetal uterus)- due to pathologies of intrauterine development of the fetus. The length of the infantile uterus of the first degree does not exceed three centimeters (together with the neck, as a rule, it is elongated), and in this case it is not possible to restore reproductive function. women with this pathology are absent.
Second degree (baby uterus)- the uterus is about three to five centimeters in size, while the ovaries are also underdeveloped, the fallopian tubes can be elongated. Menstrual function is sometimes partially preserved, and with proper treatment available in our clinic, it is possible to restore the function of childbearing.
Third degree (teenage uterus)- the length of the organ is six to seven centimeters, taking into account the length of the neck, which practically corresponds to the length of the uterus of a healthy woman. The reproductive system, as a rule, functions, and with the onset of sexual activity or with the onset of pregnancy, the size of the uterus reaches normal values.

It is worth noting that often the pathology occurs against the background of ovarian dysfunction, but sometimes ovarian failure may not be observed.

Signs of pathology

The main sign of the infantile uterus is the lag in physical development, in which menstrual irregularities are also observed. Menstruation may be absent altogether, be irregular, start late. Girls with this pathology usually have short stature, a narrow chest with undeveloped mammary glands, and a narrow pelvis. In the pubic area and under the armpits, hair grows very poorly.

If you have been diagnosed with an "infantile uterus", you may notice the accompanying symptoms:

difficulty with sexual desire or lack of it;
irregular and painful periods;
problems with conception, because pregnancy and childbearing are possible only with a mild degree of infantility of the uterus.

Infantile uterus and pregnancy

The infantile uterus is a condition in which the likelihood of successful conception and pregnancy is significantly reduced. However, even if you have heard a similar diagnosis, do not despair prematurely. First, you need to contact our clinic for examination. As a rule, with mild forms of the disease, pregnancy in a natural way is possible and the risk of its complications is minimal. With more severe degrees of the disease, conception can indeed be difficult, but even if it happens, there is a risk of complications during pregnancy and premature birth.

Only timely treatment will help to reduce such risks to a minimum. After the therapy, throughout your pregnancy, you will have to be under the close supervision of our specialist, but, nevertheless, the prognosis remains very favorable, which means you always have a chance to become a happy mother.

Sexual or genital infantilism, ascertained at the age of over 15 years in individuals with a female genotype, is characterized by anatomical and histological underdevelopment of the genital organs and their hypofunction. If sexual infantilism is accompanied by general infantilism (and this happens in half of all observations), then it becomes possible to establish the specified diagnosis at an earlier age (13-14 years).

The named pathology is found in 4-16% of girls who have undergone a preventive examination.

There are two variants of genital infantilism:

A) accompanied by ovarian insufficiency,

B) not accompanied by ovarian hypofunction.

With sexual infantilism, cases of congenital refractoriness or reduced sensitivity of the ovaries to gonadotropins, and derivatives of paramesonephric passages to steroid hormones, are not at all rare.

Algodysmenorrhea with infantilism associated, firstly, with insufficient elasticity of the uterus, which makes itself felt during the premenstrual rush of blood to it; secondly, with difficulty in the passage of menstrual blood and fragments of the endometrium through a long and narrow (with an inflection due to hyperanteflexia) cervical canal; thirdly, with anomalies of innervation, leading to discoordination of contractions of various parts of the uterus and to pathological impulses in the central nervous system.

Clinic. An infantile girl is usually short (or above average) in height, thin-boned; the epigastric angle is obtuse. The pelvis is so peculiar that in obstetric classifications it is singled out as "children's".

3 girls out of 4 have a late onset of menarche (after 16 years). Algodysmenorrhea with genital infantilism occurs unusually often - up to 80%. The pain occurs 2-3 days before menstruation and continues during them. With age, algomenorrhea decreases, and after childbirth disappears altogether.

In the symptom complex of sexual infantilism, the leading place is occupied by the state of the uterus, called hypoplasia. There are three degrees of uterine hypoplasia. Rudimentary, or embryonic, uterus (uterus foetalis) - its length along the probe is less than 3.5 cm, with most of it being the neck. This variant is rare; it adjoins rather to actually anomalies of development, than to an underdevelopment. Persistent amenorrhea is characteristic. Sometimes there is a small menstrual-like discharge.

Infantile uterus(uterus infantilis) - the length of the probe is 3.5-5.0 cm; the ratio of the neck and body is expressed as 3:1, i.e. the same as that of a girl who has not yet entered puberty. In addition, additional research methods state hyperanteflexia of the uterus, weak severity of the vaginal vaults, high location of the ovaries, excessive tortuosity of the fallopian tubes. Menstruation is rare and painful.

Hypoplastic uterus(uterus hypoplastics) - the length of the cavity, measured by the probe, reaches 5-7 cm; the ratio of the neck and body is correct - 1:3. The hypoplastic uterus is regarded not only as a result of damaging effects that occurred in the antenatal and early postnatal periods, but also as a result of local inflammatory processes or severe general diseases suffered in the recent past (in the prepubertal period). This pathology often disappears on its own after the onset of sexual activity and the onset of pregnancy.

Diagnostics . In childhood, as a rule, no complaints arise. The most typical complaints in puberty are late onset, disorder (of the hypomenstrual type) and painful menstruation. Concern is sometimes expressed about the lack of interest in members of the opposite sex.

On examination, a typical “infantile” physique attracts attention: growth deviations, insufficiently formed chest, hypoplastic mammary glands, narrowed pelvis, scanty pubic and axillary hair. The small pudendal lips protrude ahead of the large ones, the clitoris seems to be enlarged due to some hypoplasia of the external genitalia. The underdevelopment of the external genitalia with sufficient constancy is combined with sexual infantilism; at the same time, there is no direct relationship between the state of the external and internal genital organs. By the way, with partial sexual infantilism, the mammary glands are sufficiently developed, and in 37% - excessively. Some girls suffering from infantilism have a tendency to obesity.

Additional research methods are also used to diagnose infantilism. The low indicators of the girl's physical development in 35.4% of cases also indicate a lag in sexual development. Particularly indicative in this regard are the dimensions of the outer dimensions of the pelvis, in particular the conjugata externa, which barely reaches 17.5 cm by the age of 14, after which its growth slows down.

Functional diagnostic tests usually reveal an anovulatory cycle. With infantilism, the excretion of gonadotropins is increased, and sex steroids are reduced to 4-8 mcg / day; the level of 17-KS corresponds to the age norm.

When rectal-abdominal (or vaginal-abdominal) examination, the lag in the size of the uterus, the predominance of the length of the neck, and the excessive inclination of the uterus anteriorly are determined. Often a good help in the diagnosis are the results of probing the uterus (carefully!).

Among X-ray methods, pneumogynecography and X-ray hysterography have the greatest diagnostic value, the latter allowing you to trace the state of the internal pharynx (no closure), cervical canal (long, pronounced palm-shaped folds), fallopian tubes (thin, tortuous). The lag of bone age, determined, for example, using radiography of the hand, from the calendar one reaches 1-4 years in the case of infantilism.

The registration of uterine biopotentials (reduced) and rheography of the pelvic organs (insufficient blood supply) seem promising.

Treatment . Therapy of sexual infantilism is successful in most cases. If possible, the root cause of the lag of the genital organs in development is eliminated. If in adult women suffering from infantilism, hormone replacement or stimulating hormone therapy is taken, then in girls who are in puberty or adolescence, hormone therapy is not always indicated (at least not immediately). Previously, within 3 months, a "background of readiness" should be created, for which it is planned to use substances (vitamins E, C, B1, B6) intended to sensitize the genital organs to further exposure to sex hormones. At the same time, a course of ganglerone (0.04 g once a day) or diphenhydramine or tavegil in the minimum single dose of the same duration is carried out.

When starting hormone therapy, you should once again make sure that there are no vicious gonads with blastomatous potency: male false hermaphroditism, testicular feminization, hormone-producing ovarian tumor, etc. Over the next 3-4 months, cyclic administration of estrogen and progesterone (or pregnin) is taken into minimum doses. Both drugs are administered sublingually.

Approximate scheme: from the 1st to the 5th day of the cycle, half a tablet (0.01 mg) of methylestradiol 1 time per day; from the 6th to the 10th day of the cycle - one tablet (0.02 mg) of methylestradiol 1 time per day; from the 11th to the 15th day of the cycle - one tablet of methylestradiol 2 times a day (0.05 mg per day); from the 16th to the 20th day of the cycle - 2-2.5 tablets of methylestradiol 2 times a day (0.1-0.02 mg per day); from the 18th to the 20th day of the cycle - pregnin one tablet (10 mg) 1 time per day; from the 21st to the 25th day of the cycle - pregnin one tablet 3 times a day (30 mg per day).

After a course of hormonal treatment, it is necessary to take a three-month break; the next course is prescribed only if necessary, i.e., while maintaining the irregularity of the spontaneous cycle, algomenorrhea, infantile appearance. A maximum of 3-4 three-month courses can be carried out.

A more powerful hormonal effect is not physiological and is fraught with a number of immediate and delayed complications. To increase the sensitivity of tissues to estrogens from the 1st to the 20th day of the cycle, thyroidin is prescribed (0.025 g per day), which is especially indicated for obesity.

In parallel with hormonal therapy, physiotherapy (paraffin) is recommended; electroreflexotherapy (acupuncture, electropuncture, intranasal electrophoresis with vitamin B1, Shcherbak collar, electrical stimulation of cervical receptors, abdominal decompression, therapeutic exercises). Noteworthy are the principles of balneophysiotherapy according to V. M. Strugatsky, differentially applied to persons suffering from infantilism.

Treatments such as mud therapy, gynecological massage, tissue therapy, intrauterine device insertion, and gonadotropin administration, which are so widely used for the treatment of infantilism in adults, are not popular with pediatric and adolescent gynecologists. Caution is dictated by the fear of causing irreversible violations of the specific functions of the female body or blastomatous growth.

In medicine, the term "infantilism" characterizes the state of the body in which the systems are underdeveloped. Complicate the situation psycho-emotional disorders, which often occur in adolescence. Two forms of pathology are known: congenital and acquired, while each of them can affect the body partially or completely. Therefore, it is very important to identify the disorder at the beginning of its development.

Reasons for the development of pathology

The formation and development of all internal organs and systems begins when the child is still in the womb. The process is quite lengthy and continues after birth. The final stage is in adolescence. The likelihood of developing various pathologies during this period, including quite high, and with the constant impact of negative mental or physical factors, it only increases.

So, among the reasons contributing to developmental delay, doctors call:

Diseases of the cardiac, nervous and vascular systems of the body of an innate nature.
Infections with subsequent infection and illness of the child during fetal development or in early childhood.
Injuries of the skull and brain, including those that could be obtained during labor.
Venereal diseases of parents.
Pathologies of the endocrine system of the body of a congenital and acquired nature.
Vitamin imbalance in childhood.
Transferred stress during the period of bearing a child.
Rigid diets in adolescence.
Vitamin deficiency due to malnutrition.
Alcohol abuse during pregnancy.
Tobacco smoking.
Severe poisoning with toxins (alcohol, tobacco, drugs) just before conception.

Among other things, underdevelopment of the reproductive system can occur in a child if the pregnancy proceeded with pathologies. There is also a high probability of violation in the presence of extragenital diseases (the main symptom of the disease in girls is that menstruation does not go).

General signs of violation of the development of the genital organs

Infantilism can be general or partial. In the first case, developmental delay can be traced throughout the body: physical, mental, sexual. With a partial violation, problems arise with a particular system. It should be noted that sexual infantilism is more pronounced in females than in men.

The stronger sex experiences difficulties in functional terms: there is practically no attraction to a woman, reproductive abilities are impaired, erection is quite low. Of the visible signs - the penis of a man is half the standard size, the timbre of the voice is high, due to the weak production of testosterone, the hair on the chest and face practically does not grow.

Signs of female infantilism are more visible in the process of power-law classification of the disease, so they should be considered in detail.

Degrees of female infantilism

When a woman has sexual infantilism, one of two types of disorders occurs in the body: either the genitals develop incorrectly, or the entire body suffers completely. In medicine, deviations in the development of the organs of the reproductive system, namely the uterus, are more often diagnosed, which affects the reproductive function.

Infantilism is classified into three degrees:

The first is the least diagnosed form of the disease. It is characterized (its length is no more than three centimeters), and the neck is several times larger than the size of the organ. The patient does not have periods, respectively, there is no possibility of pregnancy. Reproductive function is violated in full and cannot be restored.
The second - a feature of the pathology is that the length of the neck exceeds the size of the uterus three times, despite the fact that the organ is no longer than three centimeters. Pathology is observed in the structure and location of the fallopian tubes. They have excessive bend and length. Monthly bleeding is not regular and is accompanied by severe pain. Due to the specific structure of the tubes, pregnancy often turns out to be ectopic. With prolonged and proper treatment, it is possible to restore the reproductive system.
The third - the patient's uterus is almost normal in size and is about 6-7 centimeters. The main reason for the development of pathology are infectious diseases with damage to the organs of the reproductive system, which were transferred in early childhood. With the return of a woman to normal regular sexual activity, the violations disappear without additional treatment.

Signs of female infantilism

In addition to the main degrees of pathology, sexual infantilism in women is characterized by improper functioning of the ovaries. Violation of the reproductive function and a weak manifestation of secondary sexual characteristics are due to the weak production of the hormone estrogen, because of this, the level of libido also decreases.

The disease can also be recognized by external manifestations: the chest is underdeveloped, the pelvis is narrowed, there is practically no hair in the pubic zone. The girl herself may suspect a violation due to irregular painful menstruation.

Sexual infantilism in men

Representatives of the stronger sex also suffer from a similar violation. Male infantilism is clearly expressed by a lag in sexual development. Secondary sexual characteristics and organs are underdeveloped. According to external signs, a man with a violation differs from his peers in an unnecessarily young appearance.

It is possible to suspect sexual infantilism if there is a regular lack of sexual desire for the opposite sex, there is no ejaculation at night, there is no sudden erection, the penis of a man is small in size.

It is worth noting that the size of the penis is not always small; in exceptional cases, the penis of a man is normally developed. Then the cause of infantilism is mental underdevelopment. Deviation leads to the fact that a man cannot establish contact with a woman on an emotional level and enter into intimacy with her.

Mental form of violation

In most cases, pathology does not occur solely on the background of mental disorders. It is accompanied by various, sometimes not quite obvious physical disorders. We can say that this form of the disease occurs a second time, when congenital or acquired infantilism is already progressing. It arises against the background of problems with the endocrine, cardiac and vascular systems.

A patient with a mental form of infantilism tends to behave like a child: he is frightened by everything new, bouts of hysteria often occur, he is frivolous and self-centered. More often, the treatment of this disorder is carried out in combination, with the elimination of diagnosed congenital or acquired infantilism.

Methods for diagnosing a disease

Infantilism is a complex physical and mental disorder of one or more body systems. Therefore, diagnosticians carry out a number of activities that allow you to accurately determine the etiology of the disease.

So, to make a diagnosis, the doctor may prescribe:

Conducting a consultation in conjunction with a medical survey (anamnesis).
Ultrasound scanning of the internal organs of the reproductive system.
Hormonal test.
CT examination.
Doppler tomography to assess the state of blood vessels and the usefulness of blood circulation.
X-ray examination of the uterus.
Colposcopy.
Psychological testing.

With an obvious pathology, 3 examination procedures will be enough to make a diagnosis.

All procedures and testing help specialists accurately determine discrepancies in a person's age and development of the genital organs, the presence of mental disorders. Based on this, the correct treatment regimen is determined.

Therapeutic methods of combating infantilism

Genital infantilism is best treated at the initial stage of development. If violations were identified in early childhood, then the likelihood of a complete recovery is very high. When diagnosing pathology in adulthood, treatment often does not give any results.

The success of therapy is directly dependent on the exact determination of the causes against which infantilism developed. Pathologies that have arisen under the influence of improper functioning of the endocrine, cardiac or vascular systems are eliminated by stabilization with medications. In some situations, surgery may be performed.

When diagnosed, a drug hormonal treatment regimen is used. Medicines help the body produce the missing hormones (progesterone and estradiol) in the required amount. The doctor also prescribes a course of physical procedures and drugs that strengthen the immune system.

The mental form of the disease is subject to treatment by taking tranquilizers and antidepressants. These drugs stabilize the functioning of the nervous system. In difficult situations, treatment by a psychotherapist is indicated.

Prevention

It is possible to prevent genital infantilism. Only future parents can do this, because the origin of the pathology occurs during the period of intrauterine development. Even before conception, you need to give up bad habits, lead a healthy lifestyle and reduce your stay in stressful situations.

To prevent the development of infantilism in childhood, care must be taken to ensure that the child does not come into contact with infections that can affect the organs of the reproductive system. You should also balance the diet, and teenagers should not get carried away with diets or starvation.

Genital infantilism is the result of the body being in a state of cessation of the growth of the reproductive organs before reaching maturity. With such a diagnosis, a person does not have the opportunity to conduct a full sexual life. The development of the external genital organs also does not occur.

That is, in a woman of reproductive age, the genital organs are represented by small ovaries, thin and long fallopian tubes, a small uterus and an elongated neck, the size of which does not differ from that of children.

Causes of genital infantilism

Genital infantilism basically has the problem of hormonal failure, in the pituitary gland and hypothalamus there is no production of hormones responsible for the development of the uterus and ovaries. Such disorders often characterize the first years of life and adolescence.

Disturbances in the work of the endocrine system and various diseases of a woman can lead to infantilism. If diseases affect the vessels, heart, digestive tract, and continue for a long time, then this, in many cases, ends with sexual infantilism.

It can be not only in physiology, but also in psychology. The cause of infantilism may be a general developmental delay. In people with this diagnosis, the appearance corresponds to a younger age.

Excessive parental care affects the psyche of the child, and can lead to illness. For such a person, already an adult, there are many problems in relations with persons of the opposite sex, including in the intimate sphere. Sexuality is not formed and does not develop in the presence of sexual infantilism.

For physiological and psychological infantilism, different methods of treatment are used, their choice is also influenced by the degree of this disease.

Symptoms and manifestations of infantilism

Women of short stature with a graceful and thin skeletal system, narrow pelvis, narrow shoulders may suffer from genital infantilism. Also, patients have a late onset of menstruation, the discharge is characterized by scarcity, soreness and irregularity, with the presence of headaches, weakness, fainting and nausea.

The disproportion of the genital external organs is also diagnosed (the predominance of the size of the small lips over the large ones), the enlargement of the clitoris, the openness of the gap. The size of the uterus is seriously inferior to normal, a forward bend is visible. It is the size of the uterus that underlies the determination of the degree of infantilism.

In the first degree of infantilism, the uterus has embryonic (rudimentary) dimensions. But doctors rarely meet with such an anomaly, and they cannot help the patient in any way; with genital infantilism of the second degree, the uterus has a three-centimeter size - this is the norm for a ten-year-old girl.

The high location of the ovaries, the presence of long and tortuous tubes. With the third degree of infantilism, the uterus has a length of 6-7 cm. This degree is the easiest, it is possible for the hypoplastic uterus to reach normal sizes. This process is influenced by sexual life and pregnancy.

Treatment of genital infantilism

Full diagnostics, during which anthropometric data are measured, hormonal blood tests are performed, urine and thyroid gland are analyzed, ultrasound, laparoscopy and hysterosalpinography are performed, ends with the appointment of the optimal therapy in each specific case.

Sexual infantilism is treated, as a result, the female body increases its defenses, adaptive mechanisms develop, the reproductive system improves its work. To do this, work, rest and nutrition should be subject to the optimal regime, vitamin therapy, hormone therapy, balneotherapy and gynecological massage are mandatory.

Periodically, patients turn to fertility doctors with the problem of growth retardation and development of primary or secondary genital organs. As a rule, pathology is detected even in puberty, but there are many adults whose reproductive system works the same as in adolescents or even children. In this case, doctors diagnose sexual or genital infantilism.

Medical practice notes 3 stages of development of such a pathology.

Embryonolism. Developmental anomalies are laid even inside the womb, as a result of which premature babies are born with the level of development of the embryo. Further, infantile infantilism develops, when the grown-up babies are not ahead of the chest ones in terms of physiological indicators.
Puerilism. In adolescence, boys and girls do not observe active development of secondary genital organs - they remain at the physiological level of younger schoolchildren
Juvenileism. In this case, in adults, the reproductive system corresponds to adolescence

Most often, sexual infantilism is of a chronic nature and requires long-term therapy, including radical surgical methods.

Causes of pathology

The disease is common in both female and male representatives, developing mainly for the following reasons:

disruption of the endocrine system, diseases of the pancreas, thyroid or other endocrine glands in puberty, which leads to hormonal imbalance
chromosomal abnormalities, heredity
disturbances in the development of the fetus in the womb, hypoxia or placental abruption, which led to oxygen starvation and nutrient deficiency for development
dietary disorders in childhood and adolescence (forced vegetarianism, anorexia nervosa, bulimia, starvation, therapeutic diets, fasting, etc.)
nutritional deficiencies in a teenager's menu
unhealthy living conditions (poor ecology, insufficient degree of water purification, high radioactive background, work at enterprises with chemicals, etc.)
severe infectious diseases in childhood (measles, mumps, rubella, scarlet fever and others), as well as recurrent chronic diseases of the upper respiratory tract
plastic or therapeutic operations on the organs of the reproductive system
autoimmune processes
diseases associated with immune deficiency
disorders of the circulatory system, cardiovascular pathologies
diseases of the digestive tract, etc.

Signs of male infantilism

Men with the disease are not difficult to recognize - their appearance, body constitution and voice do not correspond to age and gender parameters. The patient himself notes the following symptoms of chronic pathology:

underdevelopment or unformed external genital organs (testicles, penis, etc.)
lack of libido and sex drive
lack of spontaneous erection, pollution, ejaculation

In some cases, there is psychological infantilism as a consequence of the physical. In this case, the genitals are formed normally, but the man has a fear of the female body and sex, lack of confidence in his abilities, reduced sexual desire, erectile dysfunction up to impotence.

As for physiology, often insufficient size of the penis testifies to sexual infantilism - 2-2.5 times less than the average length. Corrective treatment is desirable to appoint up to 14 years.

Signs of female infantilism

In women, the pathology occurs in 3 forms, on which the symptoms also depend.

Rudimentary uterus. Underdevelopment of a hollow organ, the diameter does not exceed 30 mm, and most of it is the cervix. For medical practice, this congenital pathology is quite rare. The patient notes lifelong amenorrhea. Restoration of reproductive function in this case is impossible.

Underdeveloped uterus. Underdevelopment of the organ, but the diameter is from 30 mm. There is an unusually high location of the ovaries, and the fallopian tubes are more elongated and tortuous. A woman notes irregular and scanty menstruation, which may be accompanied by severe discomfort and pain.

Uterine hypoplasia. The hollow organ does not exceed 60 mm in length. As a rule, sexual infantilism in this case is the result of infections or inflammation in childhood, puberty.

The second and third forms are treatable, but it takes a long time.

Additional signs of female genital infantilism:

lack of hair growth in the genital area and armpits
underdevelopment of the mammary glands
cycle disorders
headaches and fainting
nausea
clinically narrow pelvis
pathological pregnancy
infertility

Methods of therapy

Treatment of sexual infantilism includes the following mandatory steps.

Enhance Immunity
Correction of the menu, the introduction of vitamin and nutritional supplements into the diet
hormone therapy. It is aimed at activating the processes of secretion of male or female hormones by the body, substitution treatment with synthetic drugs
Medical treatment according to symptoms and indications
Psychotherapy sessions with the possible use of neuroleptics, antidepressants, etc.
Physiotherapy (electrophoresis, balneological procedures, acupuncture, massage, etc.).
Radical treatment - plastic and other surgical procedures (for example, phalloplasty)

In women, a therapeutic effect is often observed after the onset of pregnancy - the body produces enough hormones, develops and grows to bear a child, which eliminates some signs of infantilism.

The success of treatment will depend on an integrated approach, the physical health of the patient, the psychological climate in his family and immediate environment.