When to drink panangin before meals or after. The drug Panangin: what is useful and harmful heart vitamin

medicinal product Panangin contains easily digestible potassium and magnesium, necessary for nutrition and strengthening of the heart muscle. This drug is indicated both for people with already existing diseases, for example, heart failure, arrhythmia and some others, and for healthy people as a prophylactic. Before using the drug, you should consult with your doctor, as the drug has some contraindications and side effects.

Composition and form of release

The medicine is available in two forms of release - tablets and solution.

The solution for intravenous use is colorless and odorless, in rare cases it may be a greenish transparent color. It is impossible to determine the presence in the composition of mechanical inclusions by eye. The preparation contains about 45.2 mg of potassium aspartate in 1 ml of solution, while the content of K + is 10.33 in a similar volume. Also, 1 ml of the solution contains 40 mg of magnesium aspartate, while the Mg + content is 3.37 mg. The auxiliary substance of the solution is distilled water. One ampoule contains 10 ml of solution intended for intravenous injection. In the package of the drug there are 5 ampoules of the drug, packed in plastic contours. The packaging of the medicine is cardboard.

The drug, produced in the form of biconvex round tablets, is odorless. The color of the tablets is white or almost white. The tablets are film-coated, so that their surface is shiny and uneven.

The composition of one tablet includes 166.3 mg of potassium aspartate x 1 / 2H2O, while the content of potassium aspartate in the preparation is 158 mg. One tablet contains 175 mg of magnesium aspartate x 4H2O, which corresponds to the content of 140 mg of magnesium aspartate in a tablet. The tablet also contains excipients:

• corn starch;
• talc;
• potato starch;
• magnesium stearate;
• povidone;
• colloidal silicon dioxide.

The composition of the film shell includes talc, macrogol 6000, methacrylic acid copolymer (E 100%) and titanium dioxide (color ind. 77891, E171). The drug in the form of tablets is available in polypropylene bottles packed in cardboard boxes. One vial contains 50 tablets.

pharmachologic effect

The drug Panangin affects the metabolic processes of the patient. Low levels of potassium and magnesium ions in the human body cause a number of serious diseases. This is the appearance of all kinds of metabolic changes in the myocardium, and the development of atherosclerosis of the coronary arteries, and arterial hypertension. Since Panagnin is considered a source of magnesium and potassium ions, it is able to protect the body from the appearance of these diseases.

If the balance between the content of potassium inside and outside the cells is disturbed, an increase in the toxicity of cardiac glycosides, a decrease in myocardial contractility, the occurrence of tachycardia or arrhythmia may occur.

Magnesium has an excellent anti-ischemic effect on myocardial tissue, enhances coronary blood flow.

The simultaneous content in the preparation of both magnesium ions and potassium ions is due to the fact that often there is a deficiency of both elements in the body. Simultaneous correction of their level of content gives an additive effect, it also helps to reduce the toxicity of cardiac glycosides. At the same time, their positive effect is not affected.

Endogenous aspartate acts as a conductor that accompanies magnesium or potassium ions into the cells of the body. Magnesium aspartate and potassium aspartate significantly improve myocardial metabolism.

Indications for use

The drug is prescribed to patients with various diagnoses. So, Panangin in tablets is recommended for taking with a deficiency of magnesium and potassium, caused by a lack of these substances in the daily diet.

Also, the drug is prescribed to improve the tolerance of patients with cardiac glycosides.

The tool has found wide application in the treatment of various cardiac arrhythmias (mainly ventricular arrhythmias), the treatment of myocardial infarction and heart failure.

Tablets and Panangin solution - instructions for use

The drug, produced in the form of tablets, is recommended to be taken 3 times a day, 1-2 tablets. In this case, the maximum daily dose is 3 doses of the drug, 3 tablets each. It is recommended to take the medicine only after eating, as the acidic environment of the stomach significantly reduces the effectiveness of the tablets. The duration of the course is determined by the doctor, if necessary, an additional course of treatment may be prescribed.

The solution for injection is administered intravenously by slow infusion. The maximum possible dosage at one time is 2 ampoules, repeated use of the drug is possible only after 4-6 hours. For infusion, a solution is used - the contents of 1-2 ampoules of the drug are dissolved in 50-100 ml of a 5% glucose solution.

Panangin during pregnancy

The manufacturer has no data on the use of the solution for injection in women during pregnancy. The drug, produced in the form of tablets, the manufacturer recommends using with extreme caution, especially in the first trimester of pregnancy and breastfeeding. when the possible effect of the drug on the child is maximum.

Contraindications

Panangin of any form of release is contraindicated for use in the following diseases:

• Addison's disease;
• cardiogenic shock;
• hyperkalemia;
• hypermagnesemia;
• anuria;
• oliguria;
• acute and chronic renal failure.

With individual intolerance to patients of the components of the drug, its use is also contraindicated.

Taking Panangin tablets is contraindicated in:

• hemolysis;
• acute metabolic acidosis;
• AV block I degree;
• amino acid metabolism disorders;
• severe myasthenia gravis;
• dehydration of the body.

Drug interactions and overdose

An overdose of the drug when administered intravenously is expressed in the appearance of signs of hyperkalemia or hypermagnesemia. With an overdose of tablets, cardiac conduction disturbances occur. An overdose poses some danger, so consultation with a doctor is mandatory and should occur as soon as possible.

The drug has some features of interaction with other drugs. When interacting with antiarrhythmic drugs, their negative batmo- and dromotropic effect is enhanced.

The risk of severe signs of hyperkalemia, such as asystole or arrhythmia, increases significantly with the simultaneous use of Panangin with heparin. triamterene, spironolactone, ACE inhibitors, cyclosporine.

The use of the drug together with cardiac glycosoids significantly reduces their effectiveness.

A significant decrease in intestinal motility is caused by the use of Panangin with anticholinergic agents.

The tool significantly reduces the effectiveness of tetracycline. neomycin. streptomycin and polymyxin B.

Calcium preparations reduce the effect of magnesium ions included in the preparation.

The simultaneous use of Panangin with anesthetics enhances the inhibitory effect of magnesium included in the preparation on the central nervous system.

Also, when using the drug in conjunction with calcitriol, the concentration of magnesium in the plasma increases markedly, with dexamethonium, atracurium or suxamethonium, the possibility of increasing neuromuscular blockade increases.

Side effects

When ingesting the drug in the form of tablets, the following side effects are possible:

• various manifestations of hyperkalemia and hypermagnesemia;
• AV block;
• increase in the number of extrasystoles;
• lowering blood pressure;
• a general feeling of discomfort in the pancreas;
• a burning sensation is also possible.

Vomiting can often be observed. nausea. diarrhea. Hypermagnesemia can be manifested by the following symptoms - convulsions. redness of the skin of the face, respiratory depression, fever. With hyperkalemia, the following symptoms may occur - diarrhea, paresthesia.

When the solution is injected intravenously, side effects occur, as a rule, with its rapid administration. As a rule, these are hypermagnesemia and hyperkalemia.

special instructions

Taking the drug in any manufactured form does not affect the patient's ability to drive a car or engage in work that requires increased attention or special concentration.

When using the drug, care must be taken if the patient has a disease accompanied by hyperkalemia. In addition, it is strongly recommended to control the level of ions in the blood.

Rapid intravenous administration of the drug can lead to flushing of the skin.

Application for various pathologies (for specific diseases)

The drug has shown excellent properties in the treatment of various diseases. In the first place among them, of course, coronary heart disease and myocardial infarction. Also, the drug is used for the successful treatment of arrhythmias of various origins. Often there are cases when it is necessary to replenish the reserves of magnesium and potassium in the body. Most often this happens after suffering severe infectious diseases, blood transfusion. large losses of fluid by the body, while taking diuretics, various metabolic disorders and deficiency of elements in the daily diet.

Panangin has found application for children, including newborns. The use of the drug contributes to the rapid closure of most open heart defects in newborns, strengthens the baby's heart muscle. Also, the drug is used to relieve convulsive syndrome, the main cause of which, as a rule, is a deficiency in the body of potassium and magnesium.

Analogues

The most common analogues of Panangin are:

• Asparkam;
• Asparkam-L;
• Potassium and magnesium asparaginate;
• Potassium and magnesium asparaginate Berlin-Chemie.

These drugs have similar compositions, actions, and side effects. You can find these drugs in almost any pharmacy. Less popular substitutes for the drug include Aspangin, Asparkad, Pamaton and some others.

Panangin or Asparkam?

The most popular analogue of Panangin is, of course, Asparkam. This is a time tested medicine. It was released several decades ago. The drug of domestic production, its composition is similar to the composition of Panangin. At the same time, its cost is several times lower.

However, the main indicator required of a drug is its effectiveness. Many patients who used both drugs note the greater effectiveness of Panangin.

Feedback on the application

Anton, Khabarovsk

The composition of the drug is quite harmless. Therefore, I periodically take Panangin for prevention. In addition, it contains a lot of potassium and magnesium. It is very beneficial for the body as a whole.

Natalia, Voskresensk

I have a difficult job, when I get nervous once again, arrhythmia begins. My friend is a cardiologist. it was she who advised me to try Panangin. What I liked the most was that you only need to take medicine when you really need it. And when the heart does not bother, then you don’t need to drink anything.

Marina, Moscow

And I was constantly disturbed by the beating of my heart at night, I could not even sleep peacefully. I drank a course of Panagin according to the instructions, everything returned to normal.

Victor, Perm

The doctor prescribed a course of treatment with Panangin for a month, he has not yet passed, but I feel much better. There are almost no attacks of arrhythmia.

How much does Panangin cost?

The cost of the medicine varies slightly depending on the city and the pricing policy of the pharmacy. On average, prices for Panangin are 139 rubles for tablets, and 147 rubles for a drug in the form of a solution.

Shelf life and storage conditions

It is necessary to store Panangin at a temperature of 15 to 30 degrees Celsius. At the same time, the shelf life of the drug in tablets is 5 years, in the form of a solution - 3 years. The drug must be stored out of the reach of children.

Before use, you should consult with a specialist.

Panangin

* These products are located on the website of the network of pharmacies "Thetis"

Pharmachologic effect:

Indications for use:

Used for cardiac arrhythmias (cardiac arrhythmias), caused mainly by electrolyte disorders (ionic composition disorders), primarily hypokalemia (lowering the level of potassium in the blood). The drug is indicated for rhythm disturbances associated with intoxication (poisoning) with digitalis preparations, with paroxysms of atrial fibrillation (atrial arrhythmia), recent ventricular extrasystole (ventricular arrhythmias).

Panangin is used in the treatment of coronary insufficiency (a discrepancy between the heart's need for oxygen and its delivery). There is evidence of a decrease under the influence of the drug of hypoxic (due to insufficient supply of oxygen to the tissue or a violation of its absorption) disorders of myocardial metabolism (metabolism of the heart muscle) associated with deterioration of the coronary / cardiac / blood circulation and hypokalemia (lowering the level of potassium in the blood) caused by the use of saluretic drugs (diuretics that increase the excretion of sodium and chlorine).

Mode of application:

Assign inside usually 1-2 tablets 3 times a day, and in more severe cases (with coronary circulation disorders, intolerance to digitalis preparations, etc.) - 3 tablets 3 times a day. After 2-3 weeks. reduce the dose to 1 tablet 2-3 times a day. In relatively mild cases, immediately appoint 1 tablet 2-3 times a day. Taken after meals. To stop (remove) attacks of arrhythmias, Panangin solution is administered intravenously, for which the contents of 1 ampoule (10 ml) are diluted in 20-30 ml of isotonic sodium chloride solution or 5% glucose solution and slowly injected into a vein or the contents of 1-2 ampoules are diluted in 250 -500 ml of isotonic sodium chloride solution or 5% glucose solution and injected into a vein drip. If necessary, you can add a solution of strophanthin or other cardiac glycosides.

Side effects:

When using the drug, nausea, dizziness (when injected into a vein) are possible. Patients complaining of dizziness, reduce the dose.

Contraindications:

The drug is contraindicated in acute and chronic kidney failure and hyperkalemia (high levels of potassium in the blood). In case of rhythm disturbances in combination with atrioventricular blockade (impaired conduction of excitation through the conduction system of the heart), it is not recommended to prescribe the drug.

Release form:

Available in the form of dragees and ampoules.

Storage conditions:

Cost, instructions, contraindications Panangin

The drug Panangin is a source of electrolytes important for the work of the heart: magnesium and potassium ions. In addition, the drug affects the metabolic processes.

Pharmacodynamics and pharmacokinetics of the drug

The composition of Panangin medicines includes two vital components - potassium and magnesium. Why their deficiency in the body causes a lot of problems in the work of the heart? Let's consider in more detail.

• Potassium. An important function of this element is that it maintains the membrane potential of myocytes, neurons and myocardial tissue structures. The disturbed balance between extracellular and intracellular potassium content can lead to a decrease in heart contractions, which, in turn, provokes arrhythmia, tachycardia.
• Magnesium. An important cofactor for most enzymatic reactions, in particular, energy metabolism and nucleic acid synthesis. It has an important effect on the work of the heart: it reduces the tension of contractions, as well as the frequency of the rhythm of the heart, helping to reduce the need for myocardial tissue in oxygen. Magnesium has a pronounced anti-ischemic effect on myocardial tissue.

Tandem "potassium + magnesium" in the drug Panangin reduces the toxicity of cardiac glycosides and does not affect their inotropic effect.

In addition, the combination of potassium and magnesium is based on the fact that a deficiency of one substance is often accompanied by a deficiency of another, which develops diseases such as hypertension, atherosclerosis of the coronary arteries, and arrhythmias.

Therefore, simultaneous correction of the content of both elements is required.

Indications for use

The range of possible use of the medicine Panangin is very wide, let us consider in more detail in what situation and for what health problems it helps:

• the drug is actively used for cardiac arrhythmias, which are mainly due to electrolyte disorders (or, more simply, ionic composition disorders) - a lack of potassium in the blood,
• the drug is used for cardiac arrhythmias, which are caused by intoxication with digitalis medicinal plants,
• Panangin is effective in violation of the atrial rhythm (paroxysms of their flicker),
• use the medicine for early violations of the rhythm of the heart ventricles (ventricular extrasystole),
• prescribe a remedy for the treatment of coronary insufficiency (which in the language of medicine means a discrepancy between the need for oxygen in the heart and the volume of its supply),
• Panangin is used to reduce hypoxic disorders of myocardial metabolism (lack of oxygen supply to the heart tissues or a violation of its absorption),
• with a decrease in potassium in the blood, which is caused by the use of saluretic drugs (for example, diuretics, which increase the excretion of chlorine and sodium),
• with myocardial infarction,
• as replacement therapy for potassium or magnesium deficiency in foods.

Contraindications

The drug is not indicated for all patients, there are diseases in which the use of this medicine is contraindicated:

• hyperkalemia (content in excess of the established norm of potassium in the blood),
• hypermagnesemia (magnesium content in excess of the established norm in the blood),
• cardiogenic shock,
• severe form of myasthenia gravis,
• violation of amino acid metabolism,
• acute form of metabolic acidosis,
• hemolysis, dehydration,
• insufficient function of the adrenal cortex,
• hypersensitivity to the components of the drug,
• lack of water in the body (dehydration).

Use with caution:

• in the 1st trimester of pregnancy,
• with sensitive and severe disorders of the liver,
• with a possible risk of varying degrees of edema,
• with hypophosphatemia,
• with metabolic acidosis
• with urolithic diathesis, which is associated with a violation of calcium, magnesium metabolism.

Mode of application

Panangin is prescribed using the following dosage:

• the classic norm according to the instructions is 1-2 tablets per day,
• severe cases (intolerance to the digitalis preparation, impaired coronary circulation) - 3 times a day for 3 tablets, and after 5-7 days the dose is reduced to 1 tablet 2 times a day.

The tablet is taken after a meal.

To relieve (stop) attacks of arrhythmia, the drug solution is administered slowly intravenously, for this the contents of the ampoule must be diluted with an isotonic solution of glucose or sodium chloride.

Overdose and elimination of symptoms

Cases of overdose with Panangin have not been registered to date. However, there is a possibility of symptoms of hypermagnesemia and hyperkalemia, that is, an oversaturation of potassium and magnesium preparations in the blood.

Symptoms of hyperkalemia:

• myasthenia,
• fast and prolonged fatigue,
• paresthesia,
• disorders in the work of the heart (arrhythmia, bradycardia, rarely - cardiac arrest),
• confusion.

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Symptoms of hypermagnesemia:

• vomiting (urges),
• Sopor,
• decrease in blood pressure,
• respiratory paralysis, coma,
• with a sharp increase in the concentration of magnesium in the blood, deep tendon reflexes can be inhibited.

Treatment of an overdose of Panangin consists in the abolition of the drug or in the elimination of symptoms by administering calcium chloride intravenously. In severe cases, hemodialysis is prescribed.

Interaction with other drugs

In the case of taking other medications, the patient must notify his doctor about this in order to establish the possibility of joint treatment with Panangin. Consider the interaction of this drug with others.

1. The drug is able to significantly inhibit the absorption of tetracycline and iron salts, as well as sodium fluoride. It is recommended to keep at least 3 hours between taking these medications.
2. Simultaneous use of ACE inhibitors or potassium-sparing diuretics (Triamteren, Spironolactone) increases the risk of developing hyperkalemia, therefore, potassium in the blood plasma should be monitored.
3. Under the influence of potassium contained in Panangin, the side effects of cardiac glycosides are reduced.
4. Anesthetizing drugs increase the inhibition of magnesium drugs of the central nervous system.
5. Parallel administration of Panangin and drugs Atracuronium, Decamethonium, Succinyl chloride, Suxamethonium can provoke an increase in neuromuscular blockade.
6. The drug Calcitriol increases the amount of magnesium in the blood.

Price

The price of the drug in question varies within the following limits:

• in Russia - from 128 to 139 rubles,
• in Ukraine - from 38 to 43 hryvnia.

Analogues

The most popular analogue of Panangin is Asparkam. This is a time-tested medicine - it has been produced for several decades.

This drug is of domestic production, its composition is completely similar to the composition of Panangin, while the price of Asparkam is several times less.

The main indicator of these drugs is their effectiveness, and the reviews of patients who used both drugs indicate the high effectiveness of Panangin.

The difference between Panangin and Asparkam is that Panangin is available in dragee, and Asparkam is in tablets.

The dragee is covered with a protective shell, therefore, with colitis, enterocolitis, stomach diseases, ulcers, it is better to take Panangin to protect against the active active substance.

The main difference between these drugs is that Panangin is the original, and Asparkam is an analogue, so its effect is somewhat weaker.

This medicine is a complete analogue of Panangin in composition, indications, contraindications and side effects. It is produced in the form of dragees, solutions for injections and for intramuscular administration, however, the effectiveness of the use is somewhat weaker and less pronounced than from the use of Panangin.

Instructions for use Panangin says that the drug is intended to restore the deficiency of potassium and magnesium, to improve the activity of the cardiovascular system in a particular pathology.

Description of the drug

The medicine Panangin is produced in two dosage forms. Tablets are round, biconvex, film-coated, white or grayish color, odorless. The preparation of this form of release is intended for oral administration. Tablets of 50 pieces are produced in jars or blisters placed in cardboard packaging.

Solution for injection is available in ampoules, has a white or slightly greenish tint, transparent, without visible chemical and mechanical additives. The solution is packed in 5 ampoules in a cardboard box, one ampoule - 10 ml.

International name (INN) Potassium aspartate + Magnesium aspartate.

Pharmacological group - a medicine that replenishes the deficiency of magnesium and potassium in the body.

Compound

The composition of Panangin includes potassium aspartate (tablet - 158 mg, ampoule - 45 mg), magnesium aspartate (tablet - 140 mg, ampoule - 40 mg) and auxiliary components.

The action of the drug

The drug Panangin is used in medical practice as a source of magnesium and potassium ions, serves as a catalyst for the metabolic processes of the body.

Potassium is necessary for a person for the normal functioning of myocardial fibers and the conduction system of the heart. With a deficiency of this component, the generation and conduction of impulses slows down, which negatively affects the activity of the heart muscle.

Magnesium takes part in the formation of more than three hundred enzymatic cellular systems. They play an important role in the formation of organic compounds, providing the body with energy.

Pharmacokinetics

After oral administration of the drug or using it as an injection, Panangin is rapidly absorbed and enters the bloodstream. To date, there is no exact information on the rate of absorption of potassium and magnesium by the body. The drug is excreted by the kidneys.

The drug is rapidly absorbed, providing a therapeutic effect.

Indications for use

In what area is the medicine used and what does Panangin help with? Use a remedy for the treatment of diseases of the heart and blood vessels due to a lack of potassium and magnesium ions.

Indications for Panangin's use:

• complex treatment of pathologies of the cardiovascular system;
• period of acute course of myocardial infarction;
• hypertensive heart disease;
• in the presence of pathological conduction pathways of the heart located in the ventricles;
• in the role of treatment of arrhythmias provoked by the intake of cardiac glycosides and some other medicines.

Medication dosage

Assign the described drug to patients after diagnosis. Consider how to take Panangin in various forms of release.

Tablets

Many patients are interested in how best to take Panangin - before or after meals? Experts recommend taking the tablets after meals with plenty of water.

injections

In the form of injections, the agent is administered through a dropper, very slowly (no more than 20 drops per minute), the procedure is performed exclusively by a medical professional. To prepare the solution, combine 20 ml of the product and 100 ml of glucose 5%. Repeated injection is administered if necessary after 5-6 hours.

Tablets and injections are used as an auxiliary or independent therapy for various heart diseases. Self-administration of the drug is extremely dangerous for health. The doctor must prescribe the remedy.

Panangin solution is used for setting droppers

Contraindications

Panangin and instructions for use for it states that there are contraindications for both tablets and injections.

Contraindications for oral administration:

• acute or chronic kidney failure;
• excess potassium or magnesium in the body;
• chronic adrenal insufficiency;
• atrioventricular blockades of 1-3 degrees;
• violation of metabolism in the body of amino acids;
• myasthenia gravis with severe course;
• conditions accompanied by dehydration of the body;
• acidosis.

With bradycardia, the drug is prescribed with extreme caution. When diagnosing a decrease in the frequency of heart beats, the use of the drug is prohibited.

Contraindications to the use of injections, in addition to those described above, are as follows:

• the patient's age is up to 18 years;
• pregnancy;
• period of breastfeeding;
• individual intolerance to the active and auxiliary components of the drug.

Side effects

If the dosage is violated, there are malfunctions in the functioning of the digestive system, epigastric pain, stool changes, stomach bleeding, nausea, dry mouth.

For the heart, Panangin can also cause side effects. Some patients are diagnosed with a decrease in blood pressure, heart rhythm disturbance, atrioventricular blockade.

From the side of the central nervous system, convulsions, paresthesias, impaired reflexes are noted. You can read more about the side effects and contraindications of the drug here.

Abdominal pain is one of the side effects of Panangin

Less often there is difficulty in breathing, fainting, changes in cardiogram parameters, cardiac arrest. With the development of a severe overdose, it is necessary to urgently deliver the patient to a hospital where resuscitation therapy is carried out with the introduction of dextrose or sodium chloride. In severe cases, hemodialysis is necessary.

Panangin during pregnancy

Is it possible to use the described drug during the period of bearing a baby and breastfeeding? There is no direct prohibition to prescribe the drug. The negative effect of potassium and magnesium on the child has not been confirmed. Despite this, the use of the drug during pregnancy should be done with caution, especially in the first 4 weeks.

Appointment in pediatrics

Panangin is prescribed to children only if there are serious indications for the use of the drug, mainly in the form of an injection. To set up a dropper, 10 ml of the product is diluted with 100 ml of glucose (5%).

When using tablets, the dosage of the drug is selected by the attending physician, depending on the weight and age of the patient.

Important! According to medical statistics, the use of the drug among newborns contributes to the closure of some congenital heart defects.

Panangin or Cardiomagnyl

Many patients are interested in what is better - Panangin or Cardiomagnyl, and is it possible to combine these two drugs? Taking Panangin and Cardiomagnyl together is not recommended, because both drugs have a similar composition. Medicines include magnesium, so taking them at the same time can cause an excess of it in the body. To select the appropriate remedy for a particular patient, you should contact a specialist, undergo an examination.

Drug compatibility

It is undesirable to simultaneously use the described drug with heparin drugs, angiotensin-converting enzyme inhibitors, NSAIDs, potassium-sparing diuretics, cyclosporine.

It is not recommended to simultaneously use Panangin with heparin, ACE inhibitors, non-steroidal anti-inflammatory drugs, potassium-sparing diuretics, cyclosporine and some other drugs, as this causes the risk of developing an excess of magnesium and potassium ions in the body.

It is important to consider the interaction of Panangin with other drugs

Magnesium in the composition of the product reduces the effect of Streptomycin, tetracycline drugs, Polymyxin B and Neomycin.

When Panangin is combined with anesthetics, their negative effect on the human nervous system is enhanced.

Alcohol compatibility

The compatibility of Panangin and alcohol is highly undesirable. Alcohol in itself has a negative effect on the body, and in combination with medicines can cause serious consequences. In this case, the following complications are noted:

• spasm of arteries and veins;
• impaired respiratory function;
• acute deficiency of potassium and magnesium electrolytes.

Some patients go into cardiac arrest. Given such consequences, in no case should Panangin and alcohol be combined.

Means analogues

In the reference book of drugs for radar, you can find the following analogues of Panangin:

• Plus vitamin B6 Panangin - a drug used as a dietary supplement with a lack of potassium, magnesium, vitamin B in the body;
• Aspirin Cardio - is used for the treatment and prevention of coronary heart disease, angina pectoris, in the period after heart surgery, after myocardial infarction;
• Riboxin is a complex remedy that is prescribed to patients for the treatment of coronary artery disease, heart defects, arrhythmias of various origins, atherosclerosis and other heart diseases. The composition of Riboxin includes inosine, which has a positive effect on the functioning of the heart muscle, promotes the establishment of metabolic processes, causes the necessary relaxation of the heart, and normalizes the frequency of contractions of the organ;
• Neocardil - has indications such as neurocirculatory dystonia, coronary heart disease, arterial hypertension, arrhythmias, angina pectoris and other diseases of the cardiovascular system.

It is strictly not recommended to take drugs that are similar in composition and action at the same time, it is allowed to do this only as directed by a doctor.

Terms of storage and sale

Panangin in the form of a solution is released from a pharmacy by prescription. Tablets are allowed as an over-the-counter remedy. Store the drug in a cool room at a temperature not exceeding 25 degrees.

Store the product according to the instructions for use

What the experts say

Stanislav Nikolaevich, cardiologist:

“Many patients believe that Panangin is ordinary vitamins that can be taken without fear for their health. Actually it is not. Incorrect medication can lead to severe metabolic disorders, disruption of the heart. I recommend using the remedy only on prescription in accordance with the instructions.

Anastasia Mikhailovna, cardiologist:

“Panangin is a good tool to restore the deficiency of potassium and magnesium ions in the body. The drug acts quickly, so that the therapeutic effect occurs after a short period of time. In addition, Panangin is used to reduce the side effects of certain other drugs and prevent various heart complications. I always recommend the drug to my patients.

Patient reviews

“I have taken this remedy several times in courses of 3 weeks. The doctor prescribed me Panangin in the form of tablets. I took the remedy in combination with other medicines, so I can’t say that the improvement in my well-being is only his merit. At least, I didn’t notice any negative effects, the condition returned to normal.”

Anastasia, Surgut

“I suffer from arrhythmia since my youth. After the examination, it turned out that this condition arose against the background of an imbalance in metabolic processes. After a course of treatment with Panangin, I feel much better, palpitations and shortness of breath occur less often. The drug is relatively inexpensive, the quality also suits me. ”

“Drank medicine after a heart attack. The doctor said that it is necessary to nourish the heart and restore metabolic processes. Six months after the course, I was again prescribed this drug for prevention. I was satisfied with the treatment."

Panangin

The description is current as of 06/06/2014

• Latin name: Pangin
• ATX code: A12CC30
• Active ingredient: Potassium and magnesium aspartate
• Manufacturer: Gedeon Richter (Hungary)

Composition of Panangin

The composition of the tablets

Active substances: magnesium aspartate (140 mg) and potassium aspartate (158 mg).

Additional substances: silicon dioxide, corn and potato starch, talc, povidone, magnesium stearate. The shell consists of talc, macrogol 6000, titanium dioxide, methacrylic acid copolymer.

Concentrate for solution (Panangin IV)

Contains magnesium aspartate (40 mg) and potassium aspartate (45.2 mg), as well as water for injection.

Release form

Available in tablet form, and as a concentrate solution.

pharmachologic effect

What is the cure for? It is a source of potassium and magnesium. The drug helps to restore electrolyte balance, regulates metabolic, metabolic reactions and processes, and has a pronounced antiarrhythmic effect. Potassium takes an active part in synaptic transmission, in the conduction of a nerve impulse through the fibers, in the implementation of muscle contractions, and supports the normal functioning of the heart. With impaired potassium metabolism, the excitability of muscle tissue and nerves changes. Active ion transport maintains a high potassium gradient across the plasma membrane. Small doses of potassium contribute to the expansion of the coronary arteries, and in large doses, the trace element narrows their lumen. Potassium has a moderate diuretic effect, a negative bathmotropic and chronotropic effect. Magnesium is a cofactor of three hundred enzyme reactions. Magnesium is an indispensable element in the course of processes and reactions that provide energy intake as well as expenditure. Magnesium is included in the pentose phosphate structure of DNA, takes part in the process of cell division and growth, the structure of heredity, RNA synthesis; is a natural BMCC, prevents the release of free fatty acids, catecholamines during stress, promotes the penetration of potassium ions into the cell. The drug has a stimulating effect on the intercellular synthesis of phosphates.

Mn: potassium and magnesium aspartate.

Pharmacological group: potassium and magnesium drug.

Pharmacodynamics and pharmacokinetics

Active substances play an important role in the formation of bonds between macromolecules, as well as intracellular structures and the mechanism of muscle contraction, myocardial metabolism.

According to the annotation, the drug is well absorbed. Excreted through the kidneys.

Indications for Panangin's use

Panangin tablets - what are they from?

Indications for the use of Panangin are as follows. The drug is prescribed for hypomagnesemia, hypokalemia, when taking laxatives and diuretics, glucocorticosteroids, with diarrhea, persistent vomiting, taking saluretics, with myocardial infarction, heart failure, digitalis intoxication, ventricular extrasystole, atrial extrasystole, supraventricular tachycardia, paroxysmal tachycardia.

Example of a recipe in Latin: Rp.: Dragee "Panangin" N. 20

Contraindications for Panangin

The drug is not used for intolerance to fructose, sorbitol, impaired amino acid metabolism, chronic pathology of the renal system, hemolysis, exicosis, dehydration, arterial hypotension, myasthenia gravis, atrioventricular blockade, hypermagnesemia, hyperkalemia, metabolic acidosis, Addison's disease. Panangin during pregnancy is used with caution.

Side effects

Side effects are the following manifestations: ulceration of the mucous wall of the digestive tract, epigastric pain, diarrhea, bleeding from the digestive system, drop in blood pressure, bradycardia, a paradoxical reaction in the form of an increase in the number of extrasystoles, dry mouth, nausea, flatulence, hyporeflexia, skin itching , dyspnea, thrombosis, phlebitis, paresthesia, dizziness, increased sweating, asthenia, myasthenia gravis. With rapid intravenous infusion, hypermagnesemia, hyperkalemia are noted.

Application instruction of Panangin (Way and dosage)

Tablets Panangin, instructions for use

How to drink medicine? The drug is taken orally three times a day, 2 tablets. Supportive and prophylactic therapy: three times a day, 1 tablet, course for 3-4 weeks. In some situations, a repeat course of therapy is required.

Instructions for use intravenously

Panangin's solution is administered intravenously by drip, slowly. The drug is administered at a rate of drops per minute 1-2 times a day, 300 ml each. Dosing of the drug Panangin during pregnancy is carried out according to the standard scheme for the use of the drug.

Children can take medicine from birth.

How to take Panangin for prevention?

If you ask yourself the question of the benefits and harms of Panangin, you should realize that this is a drug that has its own side effects, so you should not use it for prevention. Firstly, in this way you accustom the body to a high content of magnesium and potassium, and secondly, you can provoke an excess of these substances, which in turn can cause a lot of negative reactions.

Overdose

Manifested by muscle hypotonia, hyperkalemia, slowing of atrioventricular conduction, cardiac arrest, arrhythmia, paresthesia of the extremities, changes in the electrocardiogram. An emergency intravenous infusion of a solution of dextrose, sodium chloride is required. If necessary, peritoneal dialysis, hemodialysis is justified.

Interaction

Panagin is able to enhance the negative bathmotropic, dromotropic effects of antiarrhythmic drugs. The drug eliminates hypokalemia, which develops against the background of long-term use of diuretics, glucocorticosteroids, ISS. NSAIDs, ACE inhibitors, heparin, potassium-sparing diuretics, cyclosporine, beta-blockers increase the risk of hyperkalemia. When using general anesthetics, the inhibitory effect of Panangin on the nervous system is enhanced. Succinyl chloride, decamethonium, atracuronium, suxamethonium increase neuromuscular blockade. The use of enveloping and astringent medicines reduces the absorption of potassium and magnesium in the digestive tract. In combination with insulin, dextrose as part of a polarizing mixture, the heart rhythm normalizes in case of an overdose of cardiac glycosides, with ectopic arrhythmias, myocardial infarction. Panangin improves the tolerability of cardiac glycosides and is pharmaceutically compatible with their solutions.

Terms of sale

Does not require a prescription.

Storage conditions

In a place inaccessible to children at a temperature of degrees Celsius.

Best before date

Panangin's analogs

Alcohol compatibility

The drug is poorly compatible with alcohol, if only because the drug is usually used for problems with the heart and vascular system, and alcohol in these cases should be excluded. However, that's not all. With the simultaneous use of these substances, vasospasm may occur.

Reviews about Panangin

Reviews about Panangin on the forums are mostly positive. Buyers mark the drug as really effective, the drug facilitates the work of the heart, removes convulsions, really helps. It is noted as good pills for the heart.

Reviews about Panangin during pregnancy are as follows: the drug is often prescribed by doctors and is quite effective, despite the fact that in the description of the drug it is recommended to use the remedy with caution during this period.

Panangin price

The price of Panangin in tablets is 130 rubles, the price in ampoules is 160 rubles.

How much do pills cost in St. Petersburg? You can buy them at a cost of 125 rubles.

The price of Panangin is in Ukraine 120 and 130 UAH per tablet and solution, respectively.

• Internet pharmacies in Russia Russia
• Internet pharmacies of Ukraine Ukraine
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PaniApteka

BIOSPHERE

Education: Graduated from the Bashkir State Medical University with a degree in General Medicine. In 2011 she received a diploma and a certificate in Therapy. In 2012 she received 2 certificates and diplomas in "Functional Diagnostics" and "Cardiology". In 2013, she took courses on "Actual Issues of Otorhinolaryngology in Therapy". In 2014, she completed advanced training courses in the specialty "Clinical Echocardiography" and courses in the specialty "Medical Rehabilitation".

Work experience: From 2011 to 2014, she worked as a general practitioner and cardiologist at MBUZ Polyclinic No. 33 in Ufa. Since 2014, she has been working as a cardiologist and functional diagnostics doctor at Polyclinic No. 33 in Ufa.

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All materials presented on the site are for reference and informational purposes only and cannot be considered a method of treatment prescribed by a doctor or sufficient advice.

🔻🔻Important points of taking Panangin for prophylactic purposes

In cardiovascular diseases, Panangin is an effective medicine. It is recommended to take it with the appointment of a doctor, observing individual dosages. In addition, the drug is approved for prophylactic use.

Taking Panangin for prevention

Panangin for prevention should be used with great caution. This drug is intended to rid the body of numerous cardiovascular pathologies, including manifestations of coronary insufficiency. And also the medicine is allowed to drink to people suffering from a lack of oxygen compounds in the muscles.

Panangin reduces the number of malfunctions in the body, associated with a violation of metabolic processes in the myocardium due to a deficiency of potassium ions. In addition, the drug helps to reduce the manifestation of negative reactions caused by taking diuretic drugs that remove chloride ions with sodium from the body.

The correct use of Panangin for prevention is based on the absence of the required level of magnesium and potassium ions in the body.

Often the described medicine is prescribed for prophylactic purposes to persons suffering from a deficiency of vitamin and mineral compounds. In this regard, these tablets are drunk 2 times a day, 2 pcs. The prophylactic course should last at least a calendar month.

The cardiologist may prescribe the remedy described for a course of two weeks to persons who

• have been on a diet for a long time;
• work a lot physically;
• have been ill with the flu;
• suffered a cold.

Such preventive treatment will help to compensate for the lack of potassium and magnesium ions in people with cardiovascular diseases.

The dosage of the drug is prescribed privately, depending on the state of health of the patient. This is especially important to observe when a person's arrhythmia progresses.

Drug properties

Magnesium is characterized by an anti-ischemic effect on the myocardium, due to which these ions should always be present in the human body in the right quantities and contribute to increased blood flow through the coronary tract. From this, the pressure returns to normal.

The lack of potassium ions causes the development of dangerous types of arrhythmia with the formation of a stroke and defective heart function. Based on this, it is clear that it is dangerous to increase the daily amount of potassium consumed.

With its deficiency, taking Panangin significantly reduces the risk of developing a pre-stroke state.

The described medication strengthens the heart muscle, as well as

• makes the vascular walls elastic;
• promotes the conduction of the heart impulse;
• normalizes metabolic processes;
• prevents the manifestation of atherosclerosis;
• restores healthy functioning of the myocardium;
• protects the body from hypertension;
• reduces the possibility of premature wear and aging of the "muscle pump";
• relieves arrhythmias.

The active compounds of Panangin tend to slow down the growth of atherosclerotic plaques in the body, on the basis of which the level of blood viscosity decreases. Against this background, the likelihood of the formation of vascular thrombi decreases.

Why is Panangin prescribed?

In order for the heart to work correctly, Panangin tablets are often needed. They are indispensable for diagnosis.

• supraventricular tachycardia;
• intoxication;
• paroxysmal tachycardia;
• prolonged vomiting;
• manifestations of diarrhea;
• heart failure;
• hypomagnesemia;
• heart attack;
• spasms covering the calf apparatus;
• hypokalemia.

Panangin helps to restore a normal pulse, and tachycardia from its action practically disappears. Bradycardia (decrease in cardiac activity) is also successfully dived using the described remedy.

Instructions for use

Any heart disease must be treated correctly, observing the prescribed dosages of the drug used. Taking Panangin helps to reduce the manifestations of a heart attack in the case of its daily use in an amount of 3 pcs.

Tablets are allowed to be taken at the same time intervals, which means: morning, lunch and evening. Reduced levels of potassium and magnesium can be replenished by using the drug after a meal.

In some cases, the drug is prescribed to patients intravenously. This treatment option is characterized by better absorption of the drug with a high benefit value. Injections are prescribed exclusively by doctors, bypassing self-medication attempts.

Doctors include the medicinal content of Panangin in numerous combined therapies. In this case, the drug is diluted in glucose and delivered to the body through droppers. The dosage and frequency of such procedures is determined by the doctor for each patient individually.

Contraindications for admission

In rare cases, Panangin leads to side effects. The reason for this is an excessively long course of taking the medication with a predominance of high doses.

Among the contraindications should be noted

• failures in metabolic processes in amino acids;
• renal insufficiency;
• hypermagnesemia;
• intolerance to the components of the drug;
• hyperkalemia.

It is not advisable to drink the described tablets for persons in whose body diseases of the gastrointestinal nature are progressing. The reason for this is the interaction of the active compounds of the drug with the gastric mucosa, which can lead to irritation and pain in the abdominal area.

Side effects

Although side effects are rare, they do occur. Pregnant women should be wary of them, in the treatment of which this medication can be used.

When a woman is carrying a baby and suffering from shortness of breath and numerous heart diseases, she should not take this medicine. Pregnancy involves the use of the described medication only at the stage of the second or third trimester.

When breastfeeding, taking Panangin is harmful. In such situations, it is recommended to resort to the use of drug analogues that are less harmful to health.

The average daily dose of the drug for pregnant women is also reduced from 3 times a day, 2 tablets, to 2 times a day, 1/4 part.

Side effects are expressed in the manifestation of failures in the following systems

• cardiovascular:
• respiratory;
• digestive;
• nervous (peripheral and central).

Typically, people have a fever, nausea with bouts of vomiting, hyporeflexia, redness of the skin and convulsions.

Often, against the background of these manifestations, diarrhea begins.

In the event of the described side effects, it is necessary to visit a doctor regarding further medication.

In case of overdose

With an overdose of Panangin, the patient may develop hypermagnesemia or hyperkalemia. At the same time, people complain of a feeling of rapid fatigue and confusion. There may be a drop in blood pressure, and in severe cases, a coma.

If the described symptoms are detected, the medication should be stopped, and the patient should undergo therapy, which consists in introducing calcium chloride into the body in the form of a solution.

The health of the body, work, "interaction" of organs depend on many factors. The most important is the balance of trace elements and minerals. Magnesium and potassium take an active part in the "debugging" of the activity of blood vessels, the heart. By promoting myocardial metabolism, improving the metabolic processes of the heart, they protect a person from heart attacks, arrhythmias, tachycardia and other diseases. The body receives these substances from the outside - with food or as a result of taking special preparations: asparkam or panangin. What is good about the latter, what are the indications for Panangin medicine?

Composition and form of release

It is a drug designed to compensate for the deficiency of magnesium, potassium in the body. Consists of two active substances:

• potassium aspartate - about 160 mg;
• magnesium aspartate - 140 mg.

Pharmaceutical companies produce:

• Tablets.
• Solution for intravenous administration.

Panangin for oral use is sold in a carton. 50 tablets, for protection from sunlight, are placed in one tight polypropylene (plastic) bottle. Glass ampoules containing the drug solution are sorted by 5 pcs. on a pallet. The package of liquid panangin includes 5 ampoules of 10 ml each..

Panangin - what does the medicine help with?

What is the mechanism of action of Panangin when the patient has indications for the use of the drug? Trace elements necessary for the normal functioning of the cardiovascular system perform the following functions:

1. Stimulate the work of the myocardium, increasing cardiac conduction of impulses.
2. Strengthen the walls of blood vessels, reducing muscle tone, increasing blood flow.
3. Normalize heart rhythm.
4. Participate in the metabolic processes of the heart, relieve swelling, spasms of internal organs.

For preventive purposes, cardiologists prescribe Panangin for patients:

• with the threat of ischemia;
• after a heart attack;
• people suffering from pain in the heart, swelling;
• with heart failure, arrhythmias;
• high blood pressure, hypertension.

Indications for the use of panangin are constant spasms, pain in the muscles of the legs. The lack of active substances leads to a "clamped" state of the muscular system and a constant contraction. Intense physical activity, mental work, stressful situations are prerequisites for a deficiency of potassium and magnesium. Taking the medicine in these cases increases efficiency, enhances stress resistance.

The entry of Mg and K into the composition of the drug is due to the simultaneous deficiency of these trace elements in the body. Potassium and magnesium ions in the complex create additive synergism, when each substance exhibits an effect separately, enhancing the action of the "companion". Indications for the use of the drug is to reduce the toxicity of cardiac glycosides, without affecting the positive effect.

Instructions for use of the drug

Tablet (capsule) form has a high absorption, excreted from the body with urine. In some cases, doctors determine the indications for the simultaneous use of cardiac glycosides and panangin. An increased load on the kidneys becomes a contraindication for diseases of the latter. The pharmacokinetics of intravenous injection is unknown.

Tablets

Panangin is taken after meals. Increased acidity of the stomach reduces the absorption of active substances, slowing down the effectiveness of the impact. The duration of treatment, the need for re-admission is determined by the doctor. Indications for use are as follows:

• General cases - 1 - 2 capsules 3 times throughout the day at regular intervals.
• In case of impaired coronary circulation, immunity to digitalis preparations, intolerance - 3 capsules three times a day after meals. Gradually, under the supervision of a doctor, the dosage is reduced.

Injection

Acute cases are an indication for the use of the liquid form of panangin. 10 ml solution for injection is diluted with 20-40 ml of isotonic sodium chloride or 5% glucose. The drug is administered by injection very slowly and gradually, so as not to cause signs of hyperkalemia, hypermagnesemia: nausea, gag reflexes, dizziness.

For patients with hypersensitivity to potassium, magnesium, doctors prescribe droppers. Two ampoules of the drug are diluted with 0.3 - 0.5 liters of saline (0.9% NaCl aqueous solution) or a five percent dextrose solution. Then they are administered to the patient drip. Time interval between injections: 4 - 6 hours. It is possible to use the drug as a component of complex therapy.

Contraindications to the use of the drug

The absence of indications for the appointment, the use of panangin are:

• Heart failure (acute).
• Chronic kidney disease, acute insufficiency.
• Intolerance to the components of the drug.
• Alcoholism.
• Confusion, fatigue, myasthenia gravis, parasthesia are signs of hyperkalemia.
• Dehydration.
• Stably low blood pressure, cases of cardiogenic shock.
• Low muscle excitability, difficulty breathing, dizziness, nausea are symptoms of hypermagnesemia.

Caution, only under the supervision of a doctor, Panangin is prescribed to patients with pathology of the conduction of the heart muscle. A burning sensation, discomfort in the epidural region is the reason to reduce the dosage of the medicine. Panangin is not recommended for use for women in the first trimester of pregnancy when breastfeeding.

Drug interactions and overdose

Overdose has not been clinically recorded. The theoretical consequences are the appearance and intensification of symptoms of oversaturation of the body with magnesium and potassium: nausea, constipation or diarrhea, muscle cramps, lethargy, dehydration. Such cases require:

1. Refusal to apply.
2. The introduction of saline (300 ml).
3. Particularly severe intoxication - hemodialysis.

In the complex treatment of several drugs, it is necessary to take into account the features of their interaction:

• Adrenoblockers, diuretics spironolactone and triamterene, cyclosparine, heparin, inhibitors and non-steroidal anti-inflammatory drugs - cause an excess of K, Mg in the body with inherent symptoms.
• Panangin reduces the effect of streptomycin, tetracycline, neomycin.
• Calcium-containing drugs dramatically reduce the effect of the use of magic.
• Anesthetics - together with Mg suppress the nervous excitability of the central nervous system.
• A positive effect of the use of panangin for indications is the compatibility of the solution and cardiac glycosides, the side effects of which are leveled.

Approximate cost of Panangin in tablets and ampoules

It is possible to buy panangin in ordinary and online pharmacies in Russia. The price of the drug varies by region of the country. So, if you want to buy a drug in Moscow, the cost will be from 120 to 155 rubles. for tablets and about 160 - 165 rubles for a solution for intravenous administration. The average price of panangin is about 130 - 140 rubles. in the form of capsules and 160 - 166 rubles for a pack of ampoules.

Panangin's analogues

What is the difference between panangin and asparkam, aspangin - domestic analogues? Panangin is an original drug, more purified. Asparkam is an analogue (copy) of this medicine. Coated tablets of the drug protect the gastrointestinal tract from negative effects, so people suffering from colitis, ulcers and gastritis should give preference to it.

The price indications of the drugs also differ: being a copy, asparkam and aspangin are two to three times cheaper than the original. Most people who have indications for the use of drugs that compensate for the deficiency of K, Mg prefer panangin due to a noticeable effect on the heart muscle, leg muscles, and a decrease in the manifestations of varicose veins.

Myocardial infarction is a leading cause of high mortality and disability.

The numbers are getting more and more frightening every year, and therefore many are beginning to think about taking medications to prevent diseases of the heart and blood vessels.

Often such a drug becomes panangin, which is also actively used in traditional medicine for the treatment of other diseases of the body. But is this medicine so safe and is it worth taking it for prevention - not everyone knows.

He is sure: if he helped one, he will help him. Moreover, in the instructions for the drug, the benefits are described in simple and understandable words, and the harm and other information are described in complex medical terms that are often incomprehensible to the general population.

However, this is not as scary as it might seem at first glance.

Why and who needs panangin

From the instructions, you can understand that the "vitamin for the heart" panangin saves from cardiovascular diseases by replenishing microelements such as potassium and magnesium in the body.

On the one hand, this is true, because in case of a lack of the above elements, they are replaced by calcium and sodium, which are usually in excess in the body.

Such an unequal replacement leads to the fact that the heart cells swell, and the muscle is in a state of contraction longer, which usually leads to a violation of the heart rhythm and trophism.

On the other hand, if heart disease could be prevented by taking vitamins alone, then why are there still sick people in this world?

The drug Panangin can bring not only benefits, but also harm, since its ill-conceived intake can lead to an overabundance of these same substances, which is also unsafe. Manufacturers recommend using Panangin for such diseases:

Anyone who takes hormonal contraceptives, sedatives, diuretics and drugs for gastrointestinal diseases.

Also sick with the flu, colds and diabetes. That is, manufacturers recommend this drug to almost all of humanity, because the benefits of it are obvious, and few people think about the harm from it.

And people believe, buy, are treated. Such a frivolous attitude to the drug is also caused by the fact that Panangin is a mineral supplement.

“Since vitamins, it means nothing serious,” many people think. Meanwhile, doctors rarely prescribe this drug for the treatment of many cardiovascular diseases. And all because when taking it, you need to take into account a lot of factors that are individual for each person.

When and how much the drug should be taken to be healthy

Everyone can reduce the risk of a heart attack by 40%, and for this you need to drink only 3 tablets a day: after breakfast, after lunch, after dinner.

It is desirable to undergo such courses of treatment in the fall and spring - during these periods, vitamins are definitely not harmful, because the human body feels their shortage especially acutely. Just 2 months of daily intake of the drug is enough - and the heart is normal!

Sometimes panangin is administered intravenously by injection: this way it is better absorbed, and the benefits of taking it in this way increase.

Then the ampoule (10-20 ml) is diluted in a glucose solution of 5% concentration (50-100 ml). You can repeat the dropper after at least 6 hours and only if necessary. This method is mainly used in combination therapy.

Panangin is a drug, not a method of prevention

The drug Panangin is an antiarrhythmic drug, that is, a remedy that restores an abnormal heart rhythm. In particular, the effectiveness and benefits of panangin appear when this disorder is associated with a lack of potassium.

It is also important to take into account the fact that only a doctor can establish such a violation in each individual special case, and not a friend, acquaintance, or even the person himself who considers himself ill. At least because it requires an ECG.

As a maximum - because only a doctor will figure out what is a real violation, and what is a small flaw.

This should be especially taken into account for those who are going to take panangin for tachycardia, hypertension or pressure problems.

It may not cause harm, but it will definitely not benefit either. Therefore, if there are heart problems, you need to go to the doctor, and in no case should you self-medicate, which rarely leads to anything good.

To avoid cardiovascular diseases, you need not to drink microelements and pills, but to lead a healthy lifestyle. This truth is simple and effective maximum benefit, harm is excluded.

Eat right and vitamins will enter the body in sufficient quantities. Exercise regularly and wisely - the heart will be healthy. Forget about smoking and alcoholism - even panangin will not help to avoid diseases with these habits.

The only ones who really need the prevention of cardiovascular diseases with Panangin are people at risk.

Basically, these are those whose close relatives suffer from cardiovascular diseases. It has been proven that the probability of getting sick in such people is 10 times higher than in those who are in no way connected with the "cores". However, the risk group is also discussed with your doctor.

Fly in the ointment: side effects and contraindications

Manufacturers write that side effects are very, very rare, but however, if they are taken incorrectly or overly long, they can be observed.

This is especially true for pregnant women, who should be extremely responsible for the drugs they use.

In general, the likely side effects, that is, harm from the drug, can be observed from the side of the central or peripheral nervous systems, digestive, respiratory and even cardiovascular.

They can manifest as convulsions, hyporeflexia, redness of the skin, nausea, vomiting, and even a feeling of heat. Most often, people report diarrhea.

However, those to whom the doctor has prescribed this drug should not worry - it is good where it is really needed, which means that there will be no side effects.

The drug Panangin has many contraindications, among which it is especially worth highlighting individual intolerance, hyperkalemia, hypermagnesemia, renal failure and impaired amino acid metabolism.

You should not take the drug for those who have serious problems with the gastrointestinal tract, because even though the tablet is protected by a capsule, it dissolves and the active ingredients still interact with the walls of the stomach.

The alternative is the path to health

For example, for the treatment of blood vessels, it is much more effective to use vitamins C and P than panangin.

Yes, this drug helps, but the evidence base of conventional vitamins, even the same ascorbic acid, is much larger. Thus, this is another proof in favor of natural products.

Another important factor: panangin contains synthetic vitamins, not natural ones, because their digestibility is much lower.

There are always consequences, that is, harm from taking such “vitamins”, even if traditional medicine is silent about this. While nothing better has been invented - this is a good remedy for treatment, but only when it is required.

As a result, it is worth noting that Panangin is a high-quality and effective drug, the benefits of which are important for people suffering from certain diseases.

But this benefit is manifested only in cases of need. You should not rely on advertising and recommendations from friends, because each person is individual and what helped someone will not necessarily help you.

And self-treatment for heart diseases, especially chronic ones, is a direct and unhindered path to a heart attack. So take care of yourself, take care of your health and drink only those medicines that are prescribed by your doctor!

A drug that replenishes the deficiency of potassium and magnesium in the body

Active ingredients

Magnesium aspartate (potassium aspartate & magnesium aspartate)
- potassium aspartate (potassium aspartate & magnesium aspartate)

Release form, composition and packaging

◊ Film-coated tablets white or almost white, round, biconvex, with a slightly shiny and uneven surface, almost odorless.

Excipients: colloidal silicon dioxide, K30, magnesium stearate, talc, corn starch, potato starch.

Shell composition: macrogol 6000, titanium dioxide (E171), butyl methacrylate, dimethylaminoethyl methacrylate and methacrylate copolymer, talc.

25 pcs. - blisters (2) - packs of cardboard.
50 pcs. - polypropylene bottles (1) with control of the first opening - packs of cardboard.

pharmachologic effect

The most important intracellular cations potassium and magnesium play a key role in the functioning of many enzymes, in the formation of bonds between macromolecules and intracellular structures, and in the mechanism of muscle contractility. The intra- and extracellular ratio of potassium, magnesium, calcium and sodium ions affects myocardial contractility. Endogenous aspartate acts as an ion conductor: it has a high affinity for cells, due to the slight dissociation of its salts, ions in the form of complex compounds penetrate into the cell. Potassium and magnesium aspartate improves myocardial metabolism. The lack of potassium and / or magnesium ions predisposes to the development of arterial hypertension, atherosclerosis of the coronary arteries and the occurrence of metabolic changes in the myocardium. The intake of potassium and magnesium aspartate allows you to compensate for the lack of these electrolytes in food.

Pharmacokinetics

Magnesium

The total supply of magnesium in a human body weighing 70 kg averages 24 g (1000 mmol); more than 60% of magnesium is found in bone tissue and about 40% in skeletal muscles and other tissues. About 1% of the total magnesium reserve in the body is in the extracellular fluid, mainly in the blood serum. In healthy adults, the content of magnesium in the blood serum is in the range of 0.7-1.10 mmol / l.

Magnesium is absorbed from the gastrointestinal tract by active transport. The kidneys are the main regulator of magnesium balance in the body. 3-5% of ionized magnesium is excreted by the kidneys.

An increase in urine volume (for example, during loop diuretic therapy) leads to an increase in the excretion of ionized magnesium. If absorption of magnesium in the small intestine is reduced, subsequent hypomagnesemia leads to decreased magnesium excretion (<0.5 ммоль/сут).

Potassium

The total supply of potassium in a human body weighing 70 kg averages 140 g (3570 mmol). The total potassium reserve is somewhat less in women than in men, and decreases slightly with age. 2% of the total potassium in the body is outside the cells, and the remaining 98% is inside the cells.

Potassium is absorbed in the gastrointestinal tract. The optimal intake of potassium with food is 3-4 g (75-100 mmol) / day. The main route of potassium excretion is renal (about 90% of potassium is excreted by the kidneys daily). The remaining 10% is excreted through the gastrointestinal tract. Thus, the kidneys are responsible for long-term potassium homeostasis, as well as for the potassium content in the blood. In the short term, the potassium content in the blood is also regulated by the current of potassium between the intracellular and extracellular spaces.

Indications

To eliminate the deficiency of potassium and magnesium as part of combination therapy for:

- various manifestations of coronary heart disease (including acute myocardial infarction);

- chronic heart failure;

- heart rhythm disturbances (including arrhythmias caused by an overdose of cardiac glycosides).

Contraindications

- hypersensitivity to any of the components of the drug;

- acute and chronic renal failure;

- hyperkalemia;

- hypermagnesemia;

- Addison's disease;

- AV blockade of I-III degree;

- shock, including cardiogenic (BP less than 90 mm Hg);

- violation of amino acid metabolism;

- severe myasthenia gravis;

- hemolysis;

- acute metabolic acidosis;

- dehydration;

- age up to 18 years (efficacy and safety have not been established).

Carefully: pregnancy (especially in the first trimester) and the period of breastfeeding.

Dosage

Before use, the patient should consult a doctor.

Inside, without chewing and drinking plenty of water. The drug should be used after meals, because. the acidic environment of the stomach reduces its effectiveness.

The usual daily dose is 1-2 tablets. 3 times / day. The maximum daily dose - 2 tab. 3 times / day.

The duration of the drug and the need for repeated courses is determined by the doctor.

Data on the safety and efficacy of the drug in children and teenagers missing.

Side effects

From the digestive system: possible nausea, vomiting, diarrhea, discomfort or burning sensation in the epigastrium (in patients with anacid gastritis or cholecystitis).

From the side of the cardiovascular system: possible AV blockade, paradoxical reaction (increase in the number of extrasystoles).

From the side of water and electrolyte balance: possible hyperkalemia (nausea, vomiting, diarrhea, paresthesia), hypermagnesemia (flushing of the face, thirst, lowering blood pressure, hyporeflexia, respiratory depression, convulsions).

If any of the listed adverse reactions become serious or adverse reactions occur that are not listed in the instructions, the patient should consult a doctor.

Overdose

The risk of symptoms of hyperkalemia and hypermagnesemia increases.

Symptoms of hyperkalemia: fatigue, myasthenia gravis, paresthesia, confusion, rhythm disturbance (bradycardia, AV blockade, arrhythmias, cardiac arrest).

Symptoms of hypermagnesemia: decreased neuromuscular excitability, nausea, vomiting, lethargy, decreased blood pressure. With a sharp increase in the content of magnesium ions in the blood - inhibition of deep tendon reflexes, respiratory paralysis, coma.

Treatment: symptomatic therapy - in / in the introduction at a dose of 100 mg / min, if necessary - hemodialysis.

drug interaction

Pharmacodynamic interaction

Combined use with potassium-sparing diuretics (triamterene, spironolactone), beta-blockers, cyclosporine, heparin, ACE inhibitors, NSAIDs increases the risk of developing hyperkalemia up to the development of arrhythmia and asystole.

The simultaneous use of potassium preparations with GCS eliminates the hypokalemia caused by the latter.

Potassium reduces the undesirable effects of cardiac glycosides.

The drug Panangin enhances the negative dromo- and batmotropic effect of antiarrhythmic drugs.

Magnesium reduces the effect of neomycin, tetracycline and streptomycin.

Anesthetics increase the inhibitory effect of magnesium preparations on the central nervous system; with simultaneous use with atracuronium, decamethonium, succinyl chloride and suxamethonium, an increase in neuromuscular blockade is possible; calcitriol increases the content of magnesium in the blood plasma, calcium preparations reduce the effect of magnesium preparations.

Pharmacokinetic interaction

Drugs that have an astringent and enveloping effect reduce the absorption of asparaginate in the gastrointestinal tract, so it is necessary to observe a three-hour interval between ingestion of Panangin with the above drugs.

special instructions

Particular attention is required for patients with diseases accompanied by hyperkalemia: regular monitoring of the content of potassium in the blood plasma is necessary.

Each film-coated tablet of Panangin contains 36.2 mg of potassium. This should be considered in patients with impaired renal function or in patients receiving potassium preparations or potassium supplements.

Influence on the ability to drive vehicles and control mechanisms

No research has been done. It is not expected to affect the ability to drive vehicles and engage in activities that require an increased concentration of attention and speed of psychomotor reactions.

Terms of dispensing from pharmacies

The drug is released without a prescription.

Terms and conditions of storage

The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Shelf life - 5 years (when packed in vials), 3 years (when packed in blisters). Do not use after the expiry date stated on the packaging.