Exercises to improve the endometrium. Endometrial growth as a factor in the onset of a successful pregnancy

The endometrium is the lining of a woman's uterus where the embryo is implanted, that is, the place where conception occurs. Many women cannot get pregnant because the mucus layer is too thin. In such a situation, it is necessary to restore the normal thickness of the endometrium. Let's figure out how to increase it in order to get pregnant.

Why is the endometrium not growing?

This layer of tissue performs a very important function. This is where the fertilized egg is attached. The endometrium creates the right conditions for the development of the embryo. As soon as conception has occurred, the number of glands and blood vessels in it increases, which subsequently become part of the placenta. They provide the fetus with oxygen and nutrients. For conception to happen, the endometrium must be of normal quality, thickness, structure, and maturity. However, it may not grow naturally due to such reasons:

1. Congenital pathologies. With such deviations, certain hormones are not produced in the body in order to build up the endometrium, or their number is not enough.
2. Hormonal disorders. With some of them, the natural growth of the endometrium does not occur on the days of the cycle. Normally, the entire period, the thickness of the mucosal layer gradually increases and also decreases.
3. Poor blood supply to the uterus. This phenomenon may be the result of trauma, inflammation, diseases of the pelvic organs, abortion. With the latter, the endometrium is damaged as a result of curettage. This significantly reduces a woman's chances of getting pregnant in the future.
4. Hypoplasia of the uterus. This is the name of the discrepancy between the size of the body to the age norm. With this pathology, the layer of the mucous membrane needs to be increased.

How to increase the endometrium when planning a pregnancy

If the mucous membrane is thinner than 7-10 mm, then the probability of implantation of the fetal egg is very low. With its insufficient thickness, the pregnancy may freeze or a miscarriage will occur. To protect yourself from these troubles, you need to figure out how to build up the endometrium for conception. For this, different methods are used: treatment with hormonal and other drugs, physiotherapy procedures. In some cases, folk recipes help.

Medicines to help you get pregnant

The process of growth of mucous tissue is directly related to hormones. If you want to figure out how to quickly build up the endometrium, then pay attention to hormonal drugs. They will provide the fastest result. However, self-administration of such drugs is strictly prohibited, you must first consult with a specialist. For those who do not understand how to build up the endometrium, the following drugs will help:

• drugs with estradiol in the base;
• drugs to increase estrogen levels;
• medications with progesterone.

Proginova for endometrial growth

The drug contains estrogens, estradiol. Reception Proginova improves blood circulation in the uterus. The medicine is recommended to be drunk by girls who have had miscarriages before for recovery. Proginov's reception is one of the most important stages of preparation for IVF, before which an increase in the endometrium is necessary. The drug is allowed to be combined with other drugs.

How to build up the endometrium with Proginov to get pregnant? The method of administration is determined by the doctor. There are such options:

1. Cyclical. Proginova drink 1 tablet for three weeks in a row at the same time, skip 7 days, then repeat the course.
2. Continuous. Tablets are taken continuously.

• pregnancy for more than two months;
• breastfeeding;
• taking medications with estrogen;
• vaginal bleeding;
• tumors;
• diseases of the liver, gallbladder;
• diabetes.

Divigel with low estradiol

This drug is prescribed for those who are looking for ways to improve the endometrium for conception. It contains estradiol, a synthetic analogue of estrogen. Divigel not only thickens the mucous membrane of the uterus, but also makes the organ itself, the vagina, mammary glands and fallopian tubes function more actively. The drug is used once a day, strictly at the same time. The gel is applied to the clean skin of the shoulders, forearms, lower abdomen, buttocks, lower back. The dose is determined by the doctor. Divigel can not be smeared with inflamed areas, chest, mucous membranes. It is used only by appointment of a specialist.

Divigel should not be used for:

• diabetes mellitus;
• tumors or inflammation of the genital organs and breasts;
• predisposition to the formation of blood clots;
• pituitary tumors;
• uterine bleeding;
• violations of fat metabolism;
• pregnancy and lactation;
• diseases of the liver, kidneys.

How to take Gormel when planning a pregnancy

This is a homeopathic medicine in the form of drops, the intake of which activates the production of estrogens. The composition includes only natural ingredients and alcohol. How to build up the endometrium while taking Gormel? Dilute 10 drops of the drug in half a glass of water and drink half an hour to an hour before meals three times a day. As a rule, in addition to Gormel, other drugs with a natural composition are also prescribed. The course of treatment is from a month to three.

• pregnancy;
• breastfeeding;
• liver diseases;
• trauma or pathology of the brain.

Building up the endometrium with folk remedies

When choosing a way to increase the thickness of the endometrium, use the following recipes:

1. After menstruation until the middle of the cycle, take a decoction of the red brush, and then the hog uterus. To prepare a drink, you need to pour a tablespoon of grass with a glass of boiling water. Insist 4 hours. Use the resulting mixture four times a day with the same interval of time. The upland uterus can still be insisted on alcohol or used for douching.
2. Fresh pineapples are excellent helpers in building up the endometrium. You just need to eat one fruit a day. With a thin endometrium, eating citrus fruits, red apples, and honey helps. If you eat cherries, cranberries, strawberries or grapes, as well as salmon, mackerel, tuna and anchovies, this will also favorably affect the quality of the endometrium.
3. Prepare and drink decoctions of raspberry, mistletoe, sweet clover or clover leaves. You can use linden, hops or licorice, sage, celery root, lovage, calamus or cow parsnip for these purposes.
4. For cooking, use spices such as curry, ginger, paprika. Dill, thyme, mint and cinnamon will do.
5. Do gymnastics for pumping up the press, Kegel exercises, take up dancing.

Video: how to increase the endometrium for conception

It is impossible to conceive and endure a healthy child without providing adequate nutrition and breathing of the fetus. His life and health depends on the state of the endometrium, and then the placenta, which is formed from the inner lining of the uterus.

If the endometrium is thin, not only the successful course of pregnancy, but also the conception itself is in question.

How does thin endometrium affect pregnancy?

The main purpose of the mucous membrane lining the uterus from the inside is to create conditions for the implantation of the blastocyst and its full development. The endometrium is a hormone-dependent structure consisting of integumentary and glandular epithelium and stroma, a connective tissue that produces collagen.

The epithelium and stroma are pierced by an extensive network of blood vessels that feed the mucous membrane. When an egg is implanted, progesterone prevents the rejection of the mucosa and stimulates its development to provide the fetus with nutrients and oxygen.

If the endometrium is small, the egg does not have the opportunity to gain a foothold on the wall of the uterus. A woman with such a pathology often suffers from ectopic pregnancy, frequent miscarriages. If there is a thin endometrium in the uterus and pregnancy nevertheless occurs, its course can be associated with many problems:

• Early and late toxicosis;
• Risk of miscarriage;
• Fetal malnutrition;
• Oxygen starvation of the unborn child;
• Incorrect presentation of the fetus;
• The threat of placental abruption;
• Weakness of labor activity;
• Insufficient dilatation of the cervix during childbirth.

To avoid such problems, you need to find out the cause of insufficient growth of the endometrium and use all possible ways to solve the problem.

Causes of thinning of the endometrium

To clarify the reasons for the insufficient growth of the inner layer of the uterus, the doctor will analyze the hormonal background, prescribe an ultrasound of the pelvic organs, and an endometrial biopsy.

Immature thin endometrium - the main causes:

• Hereditary feature of hormonal regulation of the reproductive system, underdevelopment of the uterus;
• Hormonal imbalance resulting from the pathology of the endocrine system;
• Violation of the full blood supply to the pelvic organs due to injuries, inflammatory diseases of the reproductive organs;
• Taking oral contraceptives;
• Mucosal injury resulting from artificial termination of pregnancy.

After determining the cause of the pathology, the gynecologist will recommend how to build up the endometrium for conception by conservative methods.

Thin endometrium - the main symptoms

Clarification of the diagnosis, indicating that the endometrium is not growing, is performed using ultrasound. However, there are indirect signs of this pathology:

• Scanty short menstruation;
• Smearing discharge;
• irregular menstrual cycles;
• Habitual miscarriage, infertility.

A blood test for the content of estradiol, which is responsible for the maturation of the endometrium, will help establish an accurate diagnosis.

Build-up of the endometrium

There are both traditional and alternative methods that increase the thickness of the uterine lining. Treatment tactics depend on the cause of the pathology.

Conservative therapy

• Femoston;
• Proginova;
• Estradiol.

In the second half of the menstrual cycle, to form the structure of the grown endometrium, it is advisable to take Duphaston, a synthetic analogue of progesterone, or Urozhestan, its natural analogue.

If the reason for the insufficient growth of the mucosa was the intake of oral contraceptives, their use should be abandoned and Regulon should be taken within 2 months. This tactic in most cases leads to positive results.

Homeopathic drops Gormel have a mild effect, stabilizing the hormonal balance of the female body, activating the production of estrogen.

Alternative ways

Creating optimal conditions for building up the endometrium is the saturation of the diet with foods rich in salicylates. Biochemical processes involving salicylates build up the endometrium in a natural way. The menu should include:

• Nuts;
• Spices;
• Red grape wine;
• Dried fruits;
• Fruits (pineapple, apples, red grapes, tangerines, apricots);
• Berries (cherries, blueberries);
• Vegetables (cucumbers, tomatoes, bell peppers, radishes, spinach, broccoli, spinach).

To enrich the diet with essential fatty acids, fatty varieties of sea fish, foods with vitamin C are included in the diet.

To stimulate blood circulation in the pelvic organs and thereby promote the growth of the endometrium, the following methods are recommended:

• Massage (classic and acupressure);
• Acupuncture;
• Mastering belly dance;
• Aerobics;
• Hirudotherapy (treatment with leeches).

For the use of these methods, a doctor's consultation is required, taking into account contraindications.

Traditional medicine recipes

Women who have contraindications to hormone therapy (for example, breast fibroadenoma) are interested in how to build up the endometrium with folk remedies using herbal medicine.

There are plants containing phytoestrogens, the treatment of which will improve the hormonal background. Most often, for these purposes, a boron uterus is used, which contains antioxidants, trace elements, antioxidants, flavonoids, saponins, vitamin C.

Recipes with boron uterus:

On the growing moon, pour a glass of alcohol 1 tbsp. l. dry raw materials, stand for 2 weeks in a cool dark place. Take 25 drops before meals, 3 times a day.

Mother tea.

Brew 150 ml of boiling water 15 g of dry raw materials, leave for 15 minutes, take 1 tbsp. l. 3 times a day.

Solution for douching.

Pour 1 liter of boiling water 3 tbsp. herbs, insist 3 hours, filter.

A decoction of the red brush.

These recipes are used in the second half of the menstrual cycle, and in its first half you need to drink a decoction of the herb red brush: Pour 200 ml of boiling water 1 tbsp. dry herbs, leave for 4 hours, take 1 tbsp. l. every 6 hours.

The combined use of these herbs is highly effective.

Traditional medicine recipes:

A decoction of sage.

Brew like tea, drink to quench thirst during the day.

Pour 1 liter of boiling water 1 tsp. dry crushed raw materials, leave for 4 hours, strain, take ½ tbsp. 3-4 times a day.

Infusion of carrot seeds, hops, red clover, licorice, celery, linden flowers.

Before using such recipes, it is advisable to consult a phytotherapeutist.

Is it possible to build up the endometrium quickly when planning a pregnancy?

If a woman is diagnosed with endometrial hypoplasia, and she plans to conceive, it is important to perform all therapeutic measures in the complex under the supervision of a doctor. The main condition is a positive attitude and confidence that everything will work out.

So, how to increase the endometrium when planning a pregnancy:

• Apply hormonal therapy or treatment with herbal remedies;
• Saturate the diet with foods high in vitamins, trace elements, salicylates, polyunsaturated acids;
• Use massage, leech treatment, acupuncture;
• Activate blood circulation with feasible physical activity.

Consistent implementation of the doctor's recommendations, control over the state of the uterine mucosa, a positive attitude will certainly lead to the desired goal - conception and pregnancy.

The endometrium is the inner lining of the uterus that contains blood vessels. He is responsible for creating favorable conditions for fixing a fertilized egg. If pregnancy does not occur, the function of the endometrium is to remove the unfertilized egg from the body along with menstrual blood. Any pathology of the mucous layer (thickening, thinning) leads to failures in carrying a pregnancy. On average, its norm for unhindered fixation of the egg is 0.7 cm.

A thin layer of the endometrium is one of the most common pathologies that is noted in women of reproductive age. Often this problem causes infertility.

Causes and signs of pathology

The thickness of the mucous layer can be different and depends on the day of the menstrual cycle. In the early days, it does not exceed 0.5-0.9 cm, and a few days before the onset of menstruation it reaches 1.3 cm. If the thickness is below 0.5 cm, we are talking about hypoplasia (thinning) of the endometrium.

Why is the endometrium thin?

Among the predisposing factors are:

• hormonal imbalance;
• endocrine diseases;
• congenital disorders in the blood supply to the uterus;
• chronic inflammatory processes in the genitals;
• Availability ;
• underdevelopment of the uterus;
• frequent use of emergency contraception (Postinor).

It should be noted the negative impact of surgical procedures that were performed on the uterus. Especially dangerous are the consequences of scraping during abortions. In some women with thin endometrium, underdevelopment of the mammary glands, a narrow pelvis, short stature, later are noted.

The disease has no specific signs, so many women who are not planning a pregnancy may not be aware of the presence of a problem. Usually, the diagnosis of hypoplasia is established in the process of determining the reason why the pregnancy either does not occur or is interrupted in the early stages.

Scanty periods may indicate thinning. Painful periods, the presence of large blood clots, discharge in the middle of the menstrual cycle should also alert. Sometimes during the reproductive years, uterine bleeding may occur. These symptoms should be the basis for a visit to the gynecologist.

The probability of pregnancy with this pathology

In most cases, the thinning of the mucous layer of the uterus worries women planning to conceive or those who have had a long-awaited pregnancy after previous failures. What to do if the endometrium is thin and how does this affect the development of the fetus?

First of all, in women, the ability to become pregnant naturally decreases, since the thin mucous layer of the uterus prevents the ovum from fixing.

Is it possible to get pregnant with a thin endometrium?

Medicine knows cases when conception occurred even with a thickness of 0.4 cm. But, if pregnancy does occur, the risk of its interruption at an early stage, the appearance, bleeding, further weakness of labor and other complications during childbirth increases.

After conception has occurred, the endometrium continues to grow. In the first trimester, its thickness reaches 2 cm or more. Often, it is its significant increase that allows the doctor to determine pregnancy on an ultrasound scan, since the fetal egg itself may still not be noticeable. In the early stages of pregnancy, the thin endometrium requires increased attention from doctors and the appointment of immediate treatment, since it can occur at any time.

Separately, mention should be made of the IVF procedure when diagnosing a thin endometrium. This procedure is highly undesirable in such a pathology, since the chances of the embryo being successfully implanted in the uterus are extremely small. The probability of pregnancy with a thickness below 0.7 cm is no more than 15%. Therefore, the patient is advised to postpone the procedure and take appropriate measures.

Diagnosis and treatment

After studying the general symptoms, the patient is prescribed:

• Ultrasound of the uterus, which is carried out several times at different phases of the cycle;
• general urine and blood tests;
• responsible for the onset and successful course of pregnancy;
• Ultrasound of the pelvic organs;
• taking samples of uterine tissue for histological examination;
• biopsy of the body of the uterus.

These studies allow not only to establish the very fact of thinning of the endometrium, but also to determine the causes of the pathology.

Treatment for thin endometrium depends on the causes that caused it. In most cases, this is an imbalance of the hormonal system. Therefore, pregnant women with this pathology need hormonal therapy with drugs containing progesterone. Treatment regimens, dosage, duration of therapy are carried out exclusively by the attending physician on an individual basis.

If hypoplasia is caused by chronic inflammatory diseases of the genital organs, drug therapy should be aimed at eliminating the source of inflammation. In some cases, there may be indications for surgical treatment. It consists in removing the inner layer and further hormone therapy. These methods contribute to the renewal of the mucous layer of the uterus and the normalization of its thickness.

In case of circulatory disorders, treatment is indicated using conservative methods, among them: massage, physiotherapy, hirudotherapy, acupuncture, therapeutic exercises.

Medical therapy

To ensure a normal pregnancy, it is necessary to build up a thin endometrium. The patient can be prescribed combined, normalizing hormone levels, a course of treatment with estradiol, drugs containing progesterone (Utrozhestan, Duphaston).

• Duphaston

Although this drug is an artificially synthesized hormone, it successfully performs all the tasks that are inherent in progesterone. The tool effectively prepares the uterus for the upcoming pregnancy, relieves its muscle tone, prevents epithelial detachment. The usual scheme for taking the drug is from the 11th to the 25th day of the cycle, but you cannot make a decision on taking it yourself. Reception is carried out only on the recommendation of a doctor.

• Melsmon

The placental preparation Melsmon contains a placenta taken from women whose childbirth proceeded without complications. It is widely used in cosmetology, but is also used to normalize the menstrual cycle, relieve chronic fatigue syndrome, and eliminate symptoms of inflammation.

The drug is not used during pregnancy, with violations of the endocrine system, renal or hepatic insufficiency, high blood pressure.

• Actovegin

Actovegin is designed to maximize blood circulation in the genital area. Increasing blood circulation is the key to successfully overcoming hypoplasia. The standard regimen involves the use of 1-2 tablets three times a day. Usually the course of treatment lasts 4-6 weeks, determined by the doctor on an individual basis. It is also possible to take the drug during pregnancy, starting from the 16th week, when the formation of the placenta ends.

• Gormel

This remedy belongs to homeopathic medicines. It activates the synthesis of estrogen. It consists of natural ingredients and alcohol tincture. The scheme of taking the drug is as follows: 10 drops are mixed with half a glass of water and the mixture is drunk half an hour or an hour before meals three times a day. The duration of treatment can vary from one to three times a month, depending on the results obtained.

Since the drug contains alcohol, it should not be taken during pregnancy. Contraindications are also injuries and diseases of the brain, kidney failure. The drug should be completed before the stage of active pregnancy planning.

With a thin endometrium, it should be carried out only as prescribed by a doctor and under his strict control. The use of the drug Klostilbegit can lead to even greater thinning, therefore, it is usually taken simultaneously with the estrogen-containing Proginova.

Physiotherapy

Physiotherapy, indicated for thin endometrium, has several advantages. They have a gentle therapeutic effect, do not cause side effects, reduce drug dependence. Usually they are prescribed in complex therapy.

The treatment uses magnetotherapy, ultrasound, ultraviolet, massage, mud baths. The most favorable period for treatment is the first days after the end of menstruation. You can enhance the effect of physiotherapy by following the rules of nutrition, taking walks in the fresh air, and regularly doing therapeutic exercises.

Treatment with folk remedies

In addition to the use of medications, you can build up the endometrium with the help of folk remedies.

1. Sage tea. A teaspoon of the crushed plant is poured into 200 ml of boiling water and infused for several hours. The resulting infusion is taken for four months in the first half of the menstrual cycle.
2. Infusion of boron uterus. 2-3 teaspoons of the plant or ready-made sachets purchased at the pharmacy are poured with a glass of boiling water. After insisting for a quarter of an hour, you can take it daily.
3. Pineapple and pumpkin, which are allowed to be eaten in unlimited quantities, provided that there is no allergy to these products. You can use pineapple and pumpkin juice.
4. Raspberry leaf tea. Prepared leaves are poured with boiling water and tea is drunk in small quantities several times a day.
5. A combined decoction prepared from elderberry inflorescences, yarrow herbs, mint, chamomile, nettle, medicinal initials. A mixture of components taken in equal proportions is poured into 1 liter of boiling water, infused for an hour and taken half an hour before meals 3-4 times a day.

Regular treatment with folk remedies gives positive results after a few months. However, the use of any traditional medicine should be supported by drug therapy and carried out in consultation with the attending physician. It should be noted that some herbs have contraindications for use if the patient has other diseases.

Diet

The basis of successful treatment is proper nutrition. It must include foods rich in vitamins A and E, as well as foods high in salicylates. The diet should include fatty fish, vegetables (tomatoes, sweet peppers, spinach, cucumbers, beans, cabbage), fruits and berries (grapes, apples, currants, raspberries), dried fruits, honey, red wine.

A variety of spices are useful, such as paprika, thyme, cinnamon, curry. At the same time, a woman needs to limit the intake of fatty and sweet foods, as well as fast food, strong coffee and tea.

An active lifestyle plays an important role in building up the endometrium. It is useful to play sports and dance, visit the pool. This stimulates active blood circulation, which has a positive effect on his condition.

The endometrium performs a complex function - an egg is embedded in it and divides over several weeks. The inner layer of the uterine cavity plays the role of an early "placenta" for germ cells and provides nutrition, protection, and blood supply. Therefore, before pregnancy, it is necessary to prepare the maturation of a healthy endometrium. If there are problems with the reproductive system, this can be done with the help of hormone therapy, folk remedies. For healthy women, methods such as taking vitamins and including healthy foods in the diet are suitable.

Causes of endometrial growth disorder

The endometrium lines the inner lining of the uterine cavity, which is shed in women during the menstrual cycle. The formation of its cells depends on the effects of hormones produced in the ovaries.

The growth of the uterine epithelium is necessary for the implantation of a fertilized egg. In the first weeks of pregnancy, the endometrium performs a nutritional function, due to which it divides and increases in size.

Estrogen regulates the growth of the endometrium, preparing it for the implantation of an egg. In the female body, this hormone is contained in the follicles that are formed in the ovaries under the influence of the regulation of the central nervous system.

In the second phase of the cycle of a healthy woman, the content of progesterone predominates. It contributes to vascular thrombosis in the thickness of the uterus, resulting in rejection of the endometrium and menstrual bleeding develops.

Growth of the endometrium under the influence of hormones in the menstrual phase

The main causes of dystrophic changes in the epithelial layer of the uterus:

• Curettage during abortion or surgery.
• Hormonal imbalance against the background of inflammatory changes in the genital organs.
• Taking oral contraceptives or using an intrauterine device.
• Hormone-producing tumors that produce large amounts of progesterone.

Treatment

The main goal of therapy is to prepare a woman's body for conception or for IVF (in vitro fertilization). For treatment, medications and folk remedies are used. A beneficial effect is provided by the intake of vitamins and the use of certain foods.

Medicines

The drugs help to quickly build up the endometrium, as they contain a large amount of estrogen. The following medicines are actively used:

• Divigel;
• Utrozhestan;
• Proginova;
• Curantyl.

Divigel

Divigel comes in the form of a gel that is applied to the skin. Contains estradiol, carbomer, ethinol and propylene glycol. The composition includes alcohol, in which the active ingredient dissolves well. This facilitates the penetration of the drug into the blood.

The drug has a powerful estrogenic effect due to the high content of estradiol, a substance that, in chemical and biological properties, resembles a woman's own hormone.

Estradiol penetrates through the cell membrane into the nucleus of the uterine epitheliocyte and binds to specific receptors. After that, a ligand-complex is formed, which enhances the formation of nucleic acids, stimulates the growth of blood vessels and activates the work of the genome.

Actions of the drug:

• Promotes the development of the endometrium (including reduces the activity of the mammary glands, which leads to inhibition of the formation of breast milk and is an additional growth factor).
• Prevents the formation of a deficiency of sex hormones.
• Stimulates and accelerates the healing of connective tissue after surgery or abortion.
• Helps in establishing a regular menstrual cycle.

You can not use the drug in the following conditions:

• allergy to estradiol;
• cancer of the breast and other genital organs;
• uterine bleeding;
• brain tumors.

Divigel is prescribed only by an obstetrician-gynecologist after a thorough examination and study of the content of hormones in the blood.

Side effects:

• headache;
• dizziness;
• chorea (chaotic movements of the arms and legs);
• inflammation of the vein wall;
• increase in pressure;
• vomiting or bloating in case of overdose.

If these symptoms occur, you should consult a doctor.

Utrozhestan

Utrozhestan is available in the form of capsules and tablets that contain the hormone progesterone. This hormone is produced in the second phase of the menstrual cycle and is responsible for the growth, thickening and strengthening of the lining of the inner surface of the uterus. Progesterone promotes conception and pregnancy.

In women with endometrial growth disorder, Utrozhestan is used in combination with estrogenic drugs.

When taking capsules, the hormone is absorbed by the oral mucosa and circulates in the blood for up to 4-6 hours. Excreted in the urine, does not accumulate in the body.

Medication actions:

1. 1. Promotes the correct implantation of the embryo.
2. 2. Helps to get rid of infertility, restores the menstrual cycle.
3. 3. Treats menopausal conditions and luteal insufficiency.
4. 4. With IVF, it helps to prolong the 2nd phase of the cycle, in which there is an increase in the activity of the corpus luteum and growth of the endometrium.
5. 5. Helps cure endocrine infertility (lack of hormones in the ovaries) and endometriosis.

The course of treatment depends on the pathology that caused the pills to be taken. On average, it lasts from 12 to 20 days a month. The dosage is set by the doctor according to the instructions and the initial level of hormones. Overdose or misuse develops urticaria, drowsiness.

Contraindications for the appointment of Utrozhestan:

• thrombophlebitis;
• hereditary porphyria;
• liver and kidney failure;
• ischemic disorders;
• incomplete abortion.

Adverse reactions develop in the form of:

• headache;
• complete absence of menstrual bleeding for 2 cycles;
• bleeding in the middle of the cycle.

Some women develop acne on the face, vomiting, constipation, drowsiness and itchy skin. In this case, it is recommended to cancel the drug.

Utrozhestan should not be used simultaneously with drugs that inhibit liver enzymes. These include rifampicin, spironolactone, barbiturates, and antibiotics. With the joint introduction of these drugs, toxic damage to the liver occurs.

Proginova

Proginova contains a large amount of estradiol valerate, which compensates for the lack of its own estrogen in a woman's body. Valerate is a structural analogue of the hormone, so its main function is to stimulate ovulation.

The drug is absorbed in the oral mucosa, enters the bloodstream and is sent to the liver. Here a transformation reaction takes place, where the active substance is formed from valerate.

Indications for prescribing the remedy:

When planning a pregnancy, Proginova is prescribed to increase the layer of the endometrium.

The medicine should be drunk on the first day of the cycle, the course of treatment depends on the clinical manifestations. Lasts from 15 to 25 days.

• bleeding from the genitals;
• thrombophlebitis;
• hormonal tumors;
• liver pathology.

Contraindications also include breastfeeding and the age of the patient under 18 years of age. Before use, pregnancy should be excluded, since Proginova can lead to miscarriage.

When taking this drug, the following side effects are likely:

• nausea;
• skin itching;
• flatulence;
• allergy;
• swelling;
• increased heart rate.

If any of the above symptoms occur, you must stop taking the medicine.

Curantyl

Curantil is an angioprotective drug. It is used in all areas of medicine; in gynecology, the remedy is prescribed to patients with a complicated pregnancy. As part of complex therapy, the drug is also used to build up a small layer of the endometrium.

The drug contains dipyridamole, it belongs to vasodilators (substances that expand the walls of blood vessels). The drug helps to reduce the formation of blood clots and improves tissue microcirculation. Vasodilation is observed with the introduction of small doses of the drug. Curantyl acts on small-caliber vessels in the uterus.

Curantyl is used in the following cases:

• In order to maintain pregnancy in women with placental insufficiency.
• When planning pregnancy to increase the layer of the endometrium.
• To accelerate the formation of small blood vessels in the thickness of the myometrium and eliminate the phenomenon of fetal hypoxia.
• To eliminate gestosis and eclampsia in women in position.
• In order to prevent the development of malnutrition in newborns.

Curantyl tablets should be taken 2 times a day for a week. In case of emergency pathology of pregnant women, Curantyl is administered intravenously under the control of cardiac performance. Dosage selection is carried out by a doctor. An overdose is accompanied by loss of consciousness, convulsive syndrome, profuse vomiting or an attack of angina pectoris.

• violations of the heart;
• atherosclerosis;
• ischemia;
• diathesis;
• lung pathologies.

Adverse reactions are manifested by tachycardia, skin flushing, lowering blood pressure and dizziness. If the above signs are found, the administration of the drug should be stopped immediately.

Vitamins for the endometrium

They are natural antioxidants and affect many processes in the body:

1. 1. Vitamin E increases the number of small vessels in the inner lining of the uterus, which leads to an increase in the thickness of its layer.
2. 2. Vitamin C can enhance the body's immune defense and promote growth factors in the blood. They are also actively involved in the formation of epithelial cells of the uterine cavity.

These vitamins are part of the following drugs:

• Elevit Pronatal;Preparation method:

  Herbal collection of elder, drop cap, yarrow, chamomile, mint, coltsfoot, nettle is actively used at home. Herbs help to grow the endometrium together with medicines. Also, the collection can prepare for pregnancy a woman who does not have deviations in the menstrual cycle. Plants can improve the quality of the endometrium, which contributes to the birth of a healthy baby.

  Cooking method:

  1. 1. Pour 100 grams of a mixture of herbs with boiling water.
  2. 2. Drink instead of tea 2-3 times a day.

  Healthy foods

  Experts talk about the benefits of pineapple - it contains activators of the hormonal system and a large amount of vitamin C. After eating this fruit, there is an increase in blood vessels in the thickness of the uterus, the maturation of follicles in the ovaries begins.

  Eating pineapples is allowed daily, starting a few days before the expected ovulation.

  Useful foods rich in vitamins C and salicylates are blueberries, raisins, cranberries. Eating 100 grams of these berries daily promotes the growth of the endometrium.

  Every day you should eat 400 grams of fresh vegetables and fruits.

Content

The problem of "immaturity" or hypoplasia of the endometrium is especially acute when planning a pregnancy. Insufficient thickness of the endometrium may be the result, on the one hand, of general disorders: insufficiency of estrogen production, low blood supply in the branches of the uterine arteries, pathologies of blood coagulation, on the other hand, local changes in the inner uterine layer - receptor, immunological. In order to increase the thickness of the endometrium, a thorough diagnosis and search for the causes of hypoplasia is required to select the right treatment tactics.

The main manifestations of the "thin" endometrium in women are irregular menstruation, infertility, miscarriages in the early stages. The pathogenesis of insufficient thickness of the inner layer of the uterus is based on various circulatory disorders, hormonal imbalance with a pronounced lack of estrogen, and immunological disorders. In addition, a history of curettage is also a common cause of impaired growth of the endometrial layer. When cleaning, damage to the growth layer of the uterus is not excluded, in such situations absolute infertility develops, since it is this layer that is the source of growth of the functional endometrium.

The process of increasing the thickness of the endometrial layer is aimed at normalizing blood flow, hormonal regulation and suppressing infectious and inflammatory processes.

The minimum thickness of the endometrium, required for successful embryo implantation is 8 mm. The onset of pregnancy with indicators of 6-7 mm is possible, but rarely occurs and may result in spontaneous miscarriage due to the defective structure of the layer and insufficient levels of estradiol.

Diagnostics

Diagnostic measures for insufficient thickness of the endometrium are reduced to the determination of the following indicators:

• thickness of the inner uterine layer on ultrasound;
• dopplerometry of the pelvic organs, in particular, the uterine arteries;
• blood test for sex hormones;
• determination of the functioning of the thyroid gland;
• assessment of blood coagulation parameters (extended hemostasiogram);
• tests for thrombophilia, antiphospholipid syndrome, hemostasis mutations;
• determination of the level of homocysteine ​​in the blood;
• detection of antibodies to hCG in the blood;
• ) for the purpose of immunohistochemical research, determination of the presence of endometritis;
• hysteroscopy.

Equally important is the examination of the patient for STIs, vaginal dysbiosis. Often, washings of the uterine cavity are taken for examination to exclude infections.

Examination of a woman with suspected endometrial hypoplasia should begin with an ultrasound examination on different days of the menstrual cycle. The physiological cycle during normal hormonal regulation consists of two phases, the sizes of the uterine inner layer in which are different. To determine the thickness of the endometrium, ultrasound is performed 2-3 times a month. In the first days of the cycle, normal sizes vary from 5 to 9 mm, and closer to the day of the expected ovulation, the thickness of the inner uterine layer reaches 10-13 mm. The final ultrasound is performed a week after ovulation to verify the chances of embryo implantation.

The thickness of the endometrium in the first phase of the cycle, equal to less than 6 mm, gives reason to suspect hypoplasia. As a rule, in women with insufficient sizes of the inner uterine layer, deviations in indicators are observed throughout the entire menstrual cycle.

Important in the diagnosis of insufficient thickness of the endometrium is the assessment of blood flow in the uterus. With hypoplasia of the inner layer, insufficient blood flow indicators are often determined, which can be caused by pathology of blood clotting, varicose veins, thrombophlebitis, congenital or acquired vascular anomalies, mechanical factors (compression by a cyst, tumor).

After performing an ultrasound examination, the patient must take a blood test for the content of sex hormones. In the first days of the cycle (on day 2-5), the level of estradiol, follicle-stimulating hormone, luteinizing, free testosterone, DEA-sulfate, 17-OH-progesterone, cortisol is determined. 7 days after ovulation, the level of progesterone should be determined. Women with insufficient endometrial thickness have low progesterone levels.

Often, the culprit of a low endometrial thickness in a woman is the pathology of the blood coagulation system. The group of diseases that initiate hypercoagulability - increased blood clotting - is extensive. Often, patients are found to have PAI mutations, thrombophilia, elevated homocysteine ​​levels, and a number of other pathologies.

After the aspiration, specialists determine a number of its possible pathologies during histological examination, which could lead to insufficient thickness. The resulting material is treated with reagents to determine the amount of estrogen receptors (immunohistochemistry). With hypoplasia, they are found to be insufficient. Histology reveals the presence of endometritis according to a number of characteristic features.

In order to increase the chances of pregnancy, experts also resort to invasive diagnostic methods. Hysteroscopy allows the doctor to visually assess the condition of the endometrium, exclude neoplasms, adhesions, endometriosis, polyps, fibroids. In addition, when performing this procedure, it is possible to check the patency of the fallopian tubes, which also allows you to increase the range of diagnostic possibilities. In the process of hysteroscopy, the doctor selects a piece of tissue for further research (aimed biopsy). Separate diagnostic curettage is used in exceptional cases.

Methods of treatment

A complex of therapeutic measures aimed at increasing the thickness of the inner layer of the uterus should cover all links in the pathogenesis of the disease. The main directions of therapeutic methods are distinguished:

• the appointment of drugs that increase blood flow in the endometrial layer;
• elimination of infectious and inflammatory processes in the endometrium;
• taking hormonal drugs to increase estrogen levels.

When trying to increase the size of the endometrium, it is important to improve its condition in order to create an "implantation window" - a short period of time required for the introduction of a fertilized egg. That is why the treatment of hypoplasia of the inner uterine layer should be multidirectional and complex.

hormone therapy

To increase the chances of conception, it is necessary to restore the proper level of the female sex hormone estrogen. The thickness of the endometrium can be increased due to the artificial replenishment of estradiol. The chances of success are largely determined by the response of endometrial growth to hormone intake, which in turn depends on the number of estrogen receptors.

Effective and popular means, allowing to increase the thickness of the endometrium, are transdermal estrogens, produced in the form of a gel.

Hormonal gels containing estrogen to increase estradiol levels are easy to use and have a high level of safety. The gels are identical in structure to the natural hormonal substance and allow you to increase your own level in a short time. In addition, such medications significantly reduce the risk of blood clotting, which is unacceptable with an increase in the thickness of the endometrium. A topical agent applied to the skin does not go through the first stage of metabolism in the liver, which leads to the constant preservation of the required amount of estradiol in the woman's blood. This fact significantly increases the chances of increasing the size of the inner uterine layer, since estrogen fluctuations do not occur.

Most often, gynecologists prescribe Divigel, the starting therapeutic dose of which is 1 mg per day. The gel is applied to the skin of the abdomen from the 5th day of the cycle until the first day of the subsequent menstruation. In the event that menstruation does not occur, the application of the remedy is continued under the supervision of a physician. If the indicators have been increased and there are assumptions about the onset of pregnancy, Divigel continues to be used until it is confirmed by ultrasound.

In the process of treating hypoplasia of the inner uterine layer, the reaction of the endometrium to the effect of the drug is evaluated. If it is not possible to increase the thickness, the dosage of the gel is increased. The maximum dose is 2 mg per day. It should be borne in mind that it is possible to increase the dose of the agent only at the end of the 1st phase of the cycle - before ovulation. Otherwise, the growth of follicles may be slowed down. This fact should be taken into account when planning pregnancy. An increase in the dose of hormonal agents with estrogen, which allows to increase the thickness of the endometrium, is carried out with a follicle size of at least 14-15 mm.

When planning a pregnancy and trying to increase the size of the inner uterine layer with the help of hormones, ultrasound monitoring or folliculometry is necessary. Estrogens are able to suppress the growth of the dominant follicle, which can lead to an anovulatory cycle. An ultrasound examination is performed on the 5th, 9th, 13-14th day of the menstrual cycle. If necessary, perform additional ultrasound to confirm ovulation.

Treatment of endometrial hypoplasia should be comprehensive. The dose of hormones that increase the endometrium is selected individually. The terms of hormonal treatment for the onset of pregnancy are approximately 2-4 menstrual cycles. With a properly selected therapy regimen, it is possible to increase the thickness of the inner uterine layer within the specified time frame.

In addition to Divigel, estrogen tablets are also used, for example, Proginova. As a rule, to increase the thickness of the endometrium, the drug is taken for 21 days of the cycle for several months. To improve the condition of the endometrial layer in the second phase, gestagens are used (Norkolut, Dufaston, Utrozhestan). Gestagens are not included in all schemes for increasing the thickness of the uterine layer.

In addition to estrogen-based products, in order to increase the thickness of the endometrium, complexes containing polyunsaturated fatty acids, vitamin D, E are used. These substances play a role in the synthesis of hormones, and are also necessary for growth and maturation, the normal process of cell division.

When an elevated level of male sex hormones and their metabolites is detected, agents are prescribed to reduce them. To increase the production of female sex hormones and, androgens are reduced by hormonal agents. They use oral contraceptives with an antiandrogenic effect (Yarina, Belara and others), as well as corticosteroids (Dexamethasone and its preparations).

Normalization of blood circulation in the uterus

When a patient is diagnosed with pathologies of hemostasis, blood thinners are included in the treatment regimen. They also use means to strengthen the vascular wall, vitamins, medicines that improve venous outflow.

The process of drug treatment of endometrial hypoplasia is accompanied by the appointment of drugs that increase blood flow in the uterus. In addition, estrogen therapy has side effects such as blood clotting, which can also negatively affect attempts to increase the thickness of the endometrial layer.

The main group of drugs for the treatment of circulatory disorders with insufficient thickness of the endometrium are low molecular weight heparins.

Among the most popular drugs are Fraxiparine, Clexane, which are used both at the stage of pregnancy planning and at its onset to prevent miscarriage. In addition to low molecular weight heparins, Curantil, Thromboass, and low doses of Aspirin are prescribed. Means thin the blood and contribute to the normalization of blood flow in the inner uterine layer.

In order to increase blood flow in the uterus, diosmins are used - Venarus, Detralex, Phlebodia - agents that help strengthen the walls of the veins, normalize the state of venous blood, lymph flow. Especially often they are prescribed in the presence of varicose veins. Actovegin is used to activate endometrial trophism and improve regeneration processes.

Immunocorrection

The impact on the immune response in thin endometrium is relevant in combination with such pathologies as chronic endometritis, the presence of antibodies to hCG, and autoimmune diseases.

In order to increase the chances of a successful pregnancy, all infectious and inflammatory diseases of the endometrium must be eliminated. Treatment of chronic endometritis is not an easy task. Chronic inflammation is often accompanied by insufficient thickness of the endometrium. After a thorough diagnosis and confirmation of the pathology, antibiotic therapy and immunomodulation are performed. To increase the immune response, drugs such as interferons, interleukins are used. Stimulants Polyoxidonium, Likopid, Echinacea-based products are also used. With immune infertility, immunoglobulins are used.

Immunocorrection allows not only to increase the thickness of the endometrium, but also to increase its receptivity - to normalize the number of receptors for estrogen and progesterone.

In addition to immunomodulators, B vitamins and antioxidants (A, E, C) are highly effective in terms of normalizing the immune response.

herbal remedies

Hormonal treatment of thin endometrium is supplemented by the introduction of plant components into the diet, which contain the necessary substances to accelerate the growth and maturation of the cells of the inner uterine layer. These foods and plants include:

• pineapples;
• raspberries;
• mint;
• seeds and nuts;
• pumpkin;
• sage.

To increase the thickness of the endometrium, these foods and herbs can be consumed daily throughout the course of treatment.

Against the background of the main therapy, courses of leeches, acupuncture, electrophoresis with zinc, and mud therapy are used. Moderate physical activity also has a positive effect on increasing the thickness of the endometrium by improving blood circulation in the pelvis.