Salamol eco easy breathing - instructions for use, analogues, use, indications, contraindications, action, side effects, dosage, composition. Salamol eco easy breathing, dosed aerosol for inhalation Description salamol eco easy breathing

Pharmacodynamics. Anti-asthma drug. Salbutamol, which is part of the drug, is a selective β2-adrenergic receptor agonist, which acts mainly on β2-adrenergic receptors of the bronchi with a slight effect on β2-adrenergic receptors of other localization. In a therapeutic dose, it has a pronounced bronchodilator effect. Prevents and eliminates bronchospasm, increases VC, reduces the tone and contractile activity of the myometrium. Reduces the release of histamine, slow-reacting substance of anaphylaxis and other biologically active substances from macrophages. With prolonged use of salbutamol, the sensitivity of receptors to it decreases, which leads to a weakening of the drug. The bronchodilating effect begins to appear after 10-15 minutes and lasts at least 3 hours.
After inhalation, 10-15% of the active substance enters the bronchi, the rest - in the gastrointestinal tract. In the bronchi, 90% of the administered dose is absorbed. In the lungs, salbutamol does not appear to be metabolized. The effect of the drug largely depends on the correct inhalation technique, which determines the ratio of the inhaled and swallowed dose.

Indications for use of the drug Salamol-eco easy breathing

Treatment and prevention of asthma attacks in asthma, obstructive bronchitis and emphysema, accompanied by airway obstruction. Treatment for bronchospasm of various origins. Prevention of stress-related asthma attacks.

Application of Salamol-eco easy breathing

adults
Acute bronchospasm - 1-2 inhalation doses. Prevention of breathlessness caused by stress or allergens - 2 inhalations before exercise or allergen action. Preventive and maintenance therapy - 2 inhalations 3-4 times a day.
Children over the age of 5
Acute bronchospasm - 1 inhalation. Prevention of an asthmatic attack caused by physical stress or an allergen - 1 inhalation before physical stress or the action of an allergen. Preventive and maintenance therapy - 1 inhalation 3-4 times a day.
For adults and children over the age of 5 years, the maximum daily dose is 8 inhalations. Each subsequent use of the drug is carried out no earlier than 4 hours later.
Rules for using an inhaler
Shake the inhaler several times before use. Holding the inhaler upright, open the lid. Then take a deep breath, close the mouthpiece tightly with your lips and make sure that the hand does not block the ventilation holes, and the inhaler is in an upright position. Next, take a slow maximum breath through the mouthpiece, hold your breath for ≥10 s. Then remove the inhaler from the mouth and exhale slowly. After use, while continuing to hold the inhaler in an upright position, close the lid. If repeated inhalation is required, wait at least 1 min and then repeat the process.
Cleaning the inhaler
Unscrew the top of the inhaler, remove the metal cartridge and, without lowering it into the water, rinse the body of the inhaler in warm water and dry. Insert the bottle into place. Close the lid and screw the top of the inhaler to its body. Do not wash the top of the inhaler!

Contraindications to the use of the drug Salamol-eco easy breathing

Hypersensitivity to the components of the drug, children under the age of 5 years. During pregnancy and lactation, SALAMOL-ECO EASY BREATHING is prescribed only if there are strict indications, when the expected benefit to the mother outweighs the potential risk to the child.

Side effects of Salamol-eco easy breathing

Therapy with β2-agonists can cause significant hypokalemia. This effect is enhanced with the simultaneous use of xanthine derivatives, corticosteroids, diuretics, or with concomitant hypoxia. In patients with hypersensitivity to the drug or when using it in high doses, peripheral vasodilation with minor compensatory tachycardia may occur. Rarely - transient spasms, skeletal muscle tremor, especially of the hands, headache. Very rarely - hypersensitivity reactions: angioedema, urticaria, bronchospasm; hypotension and collapse.

Special instructions for the use of the drug Salamol-eco easy breathing

It is recommended to control the level of potassium in the blood, especially in severe asthma. With caution, the drug is prescribed to patients with hypersensitivity to salbutamol, as well as thyrotoxicosis, diseases of the cardiovascular system (CHD, heart rhythm disturbances), hypertension, diabetes mellitus, pheochromocytoma and ketoacidosis. Avoid getting the drug in the eyes.

Interactions of the drug Salamol-eco easy breathing

Salbutamol should not be co-administered with non-selective β-adrenergic blockers (including eye drops containing β-adrenergic blockers). The parallel use of cardioselective β-adrenergic blockers does not reduce the effectiveness of salbutamol.
Simultaneous use with xanthine derivatives, diuretics and corticosteroids can cause severe hypokalemia. Simultaneously with salbutamol, general anesthetics, tricyclic antidepressants, maprotiline, ergotamine, MAO inhibitors should not be taken. When combined with digoxin, the risk of cardiac arrhythmia due to hypokalemia due to the use of β-adrenergic blocker agonists increases.

Overdose of the drug Salamol-eco easy breathing, symptoms and treatment

It is manifested by tremor, tachycardia, mental stress, headache and peripheral vasodilation. There is no specific antidote. Treatment is symptomatic. Cardioselective β-adrenergic blockers are usually used in low doses. High doses of β-blockers should not be used due to the risk of developing bronchospasm.

Storage conditions of the drug Salamol-eco easy breathing

At a temperature not higher than 30 °C. Protect from direct sunlight and freezing! The bottle is under pressure. Do not throw into fire or disassemble, even if it is empty.

List of pharmacies where you can buy Salamol-eco easy breathing:

• St. Petersburg

Prevention and relief of bronchospasm in:

• Bronchial asthma.
• Chronic obstructive pulmonary disease (COPD).
• Chronic bronchitis.
• Emphysema of the lungs.

Contraindications to the use of Salamol Eco Easy Breathing

• Heart rhythm disturbances (paroxysmal tachycardia, polytopic ventricular extrasystole), tachyarrhythmias.
• Myocarditis.
• Heart defects, aortic stenosis.
• Cardiac ischemia.
• thyrotoxicosis.
• Decompensated diabetes mellitus.
• Glaucoma.
• Epilepsy.
• Pyloroduodenal constriction.
• Liver failure.
• Renal failure.
• Pregnancy.
• Simultaneous reception of non-selective beta-blockers.
• Children's age up to 2 years.
• Hypersensitivity to any component of the drug.

Carefully prescribe the drug in the following cases:

• Chronic heart failure.
• Hyperthyroidism.
• Arterial hypertension.
• Pheochromocytoma.

Adults and children over 12 years old - 100-200 mcg of Salamol Eco (1-2 inhalation doses) to relieve asthma attacks.
To control the course of mild asthma - 1-2 doses 1-4 times a day and moderate severity of the disease - in the same dosage in combination with other anti-asthma drugs.
For the prevention of physical effort asthma - 20-30 minutes before exercise 1-2 doses per dose.
For children from 2 to 12 years of age with the development of an attack of bronchial asthma, as well as to prevent attacks of bronchial asthma associated with exposure to an allergen or caused by physical activity, the recommended dose is 100-200 mcg (1 or 2 inhalations).
The daily dose of Salbutamol should not exceed 800 mcg (8 inhalations).

Application of Salamol Eco Easy Breathing during pregnancy and lactation

The drug is contraindicated for use during pregnancy. During lactation (breastfeeding) is prescribed only in cases where the expected benefit to the mother outweighs any potential risk to the child.

pharmachologic effect

Salbutamol is a selective ?-2-adrenergic antagonist. In therapeutic doses, it acts on ?-2-adrenergic receptors of the smooth muscles of the bronchi, providing a pronounced bronchodilator effect, prevents and relieves bronchospasm, and increases the vital capacity of the lungs. Prevents the release of histamine, a slow reacting substance from mast cells and neutrophil chemotaxis factors. It causes a slight positive chrono- and inotropic effect on the myocardium, dilation of the coronary arteries, and practically does not reduce blood pressure. It has a tocolytic effect: it lowers the tone and contractile activity of the myometrium. The action of the drug begins 5 minutes after inhalation and lasts for 4-6 hours. It has a number of metabolic effects: it reduces the content of K + in plasma, affects glycogenolysis and insulin release, has a hyperglycemic (especially in patients with bronchial asthma) and lipolytic effect, increases the risk of acidosis.

Side effects Salamol Eco Easy Breathing

From the side of the central nervous system: tremor of the hands (a typical side effect for all beta2-agonists), headache, dizziness, irritability, anxiety, sleep disturbance, insomnia. The drug can cause excitation and increased motor activity in children.

From the side of the cardiovascular system: expansion of peripheral vessels (hyperemia of the skin of the face), a slight compensatory increase in heart rate, increased blood pressure. Arrhythmias (including atrial fibrillation, supraventricular tachycardia and extrasystole) may occur.

Allergic reactions: in isolated cases - angioedema, urticaria, erythema, nasal congestion, bronchospasm, arterial hypotension, collapse.

From the digestive system: nausea, vomiting, dyspepsia.

From the respiratory system: paradoxical bronchospasm, irritation of the mucous membrane of the mouth and throat (pharyngitis), cough.

From the side of metabolism: possible hypokalemia (may pose a serious danger to the patient), reversible hyperglycemia.

Others: muscle cramps.

special instructions

In patients with severe or unstable asthma, the use of bronchodilators should not be the main or only therapy. If the effect of the usual dose of Salamol Eco becomes less effective or less prolonged (the effect of the drug should last at least 3 hours), the patient should consult a doctor. Frequent use of salbutamol can lead to increased bronchospasm, sudden death, and therefore, between taking regular doses of the drug, it is necessary to take breaks of several hours. An increase in the need for short-acting inhaled ?-2-adrenergic agonists to control asthma symptoms indicates an exacerbation of the disease. In such cases, the patient's treatment plan should be reviewed and the issue of prescribing or increasing the dose of inhaled or systemic glucocorticosteroids (GCS) should be decided. Therapy with ?-2-adrenergic agonists can lead to hypokalemia. Particular caution is recommended in the treatment of severe attacks of bronchial asthma, since in these cases hypokalemia may increase as a result of the simultaneous use of xanthine derivatives, corticosteroids, diuretics, and also due to hypoxia. In such situations, it is necessary to control the level of potassium in the blood serum. A can of Salamol Eco cannot be pierced, disassembled or thrown into a fire, even if it is empty. Like most other aerosol inhalants, Salamol Eco may be less effective at low temperatures. When cooling the cartridge, it is recommended to remove it from the plastic case and warm it with your hands for several minutes.

Overdose

Symptoms: nausea, vomiting, irritability, hallucinations, tachycardia, ventricular flutter, peripheral vasodilation, lowering blood pressure, hypoxemia, acidosis, hypokalemia, hyperglycemia, muscle tremor, headache.

Treatment: drug withdrawal, cardioselective beta-blockers; symptomatic therapy. If an overdose is suspected, serum potassium levels should be monitored.

drug interaction

Theophylline and other xanthines, when used simultaneously with salbutamol, increase the likelihood of developing tachyarrhythmias; means for inhalation anesthesia, levodopa - severe ventricular arrhythmias. It is not recommended to simultaneously use Salamol Eco and non-selective beta-adrenergic blockers, such as propranolol. Monoamine oxidase inhibitors and tricyclic antidepressants increase the effect of salbutamol and can lead to a sharp decrease in pressure. Salbutamol enhances the action of stimulants of the central nervous system, side effects of thyroid hormones, cardiac glycosides. Reduces the effectiveness of antihypertensive drugs, nitrates. Hypokalemia may increase as a result of the simultaneous use of xanthine derivatives, glucocorticosteroids, diuretics. Simultaneous appointment with anticholinergics (including inhalation) may increase intraocular pressure.

Storage conditions

Store at a temperature not exceeding 30°C, protected from direct sunlight.

Photo of the drug

Latin name: Salamol Eco Easy Breath

ATX code: R03AC02

Active substance: salbutamol (salbutamol)

Manufacturer: NORTON WATERFORD (Ireland)

The description applies to: 07.12.17

Aerosol for inhalation dosed, breath-activated - 1 dose:

• active substance: salbutamol sulfate - 124 mcg (equivalent to 100 mcg of salbutamol);
• excipients: hydrofluoroalkane (HFA-134a) - 26.46 mg; ethanol - 3.42 mg.

Aerosol for inhalation dosed, breath-activated, 100 mcg/dose. 200 doses of the active substance in an aluminum can filled with aerosol under pressure. The aluminum cartridge is in a breath-activated aerosol inhaler (Easy Breathing). 1 aerosol inhaler with a can in a cardboard box.

pharmachologic effect

Bronchodilator.

Instruction

Shake the inhaler several times. Then, holding the inhaler upright, open the lid. Take a deep breath. Cover the mouthpiece tightly with your lips. Make sure that your hand does not block the ventilation holes on the top of the inhaler and that the inhaler is in an upright position.

Take a slow maximum breath through the mouthpiece. Hold your breath for 10 seconds or as long as you feel comfortable. Then remove the inhaler from the mouth and exhale slowly. After use, continue to hold the inhaler in an upright position. Close the lid.

If you need to take more than one inhalation, close the lid, wait at least 1 min, and then repeat the inhalation process.

Inhaler cleaning. Unscrew the top of the inhaler. Pull out the metal can. Rinse the bottom of the inhaler in warm water and dry. Insert the bottle into place. Close the lid and screw the top of the inhaler to its body. Do not wash the top of the inhaler. If the inhaler does not work properly, you should unscrew its upper part and manually press the can.

Dosage of Salamol eco easy breathing

Inhalation.

Adults and children over 12 years old: 100–200 mcg of Salamol Eco Easy Breathing (1–2 inhalation doses) to relieve asthma attacks. To control the course of mild asthma - 1-2 doses 1-4 times a day and moderate severity of the disease - in the same dosage in combination with other anti-asthmatic drugs. For the prevention of asthma physical effort - 20-30 minutes before exercise 1-2 doses per reception.

Children from 2 to 12 years of age: with the development of an attack of bronchial asthma, as well as to prevent attacks of bronchial asthma associated with exposure to an allergen or caused by physical activity, the recommended dose is 100-200 mcg (1 or 2 inhalations).

The daily dose of salbutamol should not exceed 800 mcg (8 inhalations).

Instruction SALAMOL ECO EASI BREATHE (SALAMOL ECO EASI BREATHE)

ATX code: R03AC02

Company: Teva

NORTON WATERFORD

Shelf life and storage conditions:

The drug should be stored in a place protected from direct sunlight, out of the reach of children, at a temperature not exceeding 30°C; do not freeze. Shelf life - 3 years.

Terms of dispensing from pharmacies:

The drug is dispensed by prescription.

Indications for use

Prevention and relief of bronchospasm:

- with bronchial asthma;

- with chronic obstructive pulmonary disease (COPD);

- with chronic bronchitis;

- with emphysema.

Pharmacokinetics

After inhalation, up to 21% of the dose enters the respiratory tract. The rest remains in the device or settles in the oropharynx and is then swallowed.

The portion of the dose that enters the respiratory tract is absorbed by lung tissues, does not undergo biotransformation and enters the bloodstream. When released into the systemic circulation, salbutamol is partially metabolized in the liver and excreted mainly by the kidneys in unchanged form or in the form of phenolic sulfate.

Part of the dose that enters the gastrointestinal tract is absorbed and undergoes a "first pass" effect through the liver, turning into phenolic sulfate.

The binding of salbutamol to plasma proteins is 10 %. C max in blood plasma - 30 ng / ml . T 1/2 - 3.7-5 hours

It is excreted mainly by the kidneys in unchanged form and in the form of a conjugate. Most of the dose of salbutamol administered by inhalation is excreted within 72 hours.

Contraindications

- violations of the heart rhythm (paroxysmal tachycardia, polytopic ventricular extrasystole), tachyarrhythmia;

- myocarditis;

- heart defects, aortic stenosis;

- ischemic heart disease, tachyarrhythmia;

- thyrotoxicosis;

- decompensated diabetes mellitus;

- glaucoma;

- epilepsy;

- pyloroduodenal narrowing;

- liver failure;

- renal failure;

- pregnancy;

- simultaneous reception of non-selective beta-blockers;

- children's age up to 2 years;

- hypersensitivity to any component of the drug.

FROM caution the drug is prescribed for chronic heart failure, hyperthyroidism, arterial hypertension, pheochromocytoma.

Side effects

From the side of the central nervous system: tremor of the hands (a typical side effect for all beta 2-agonists), headache, dizziness, irritability, anxiety, sleep disturbance, insomnia. The drug can cause excitation and increased motor activity in children.

From the side of the cardiovascular system: expansion of peripheral vessels (hyperemia of the skin of the face), a slight compensatory increase in heart rate, increased blood pressure. Arrhythmias (including atrial fibrillation, supraventricular tachycardia and extrasystole) may occur.

Allergic reactions: in isolated cases - angioedema, urticaria, erythema, nasal congestion, bronchospasm, arterial hypotension, collapse.

From the digestive system: nausea, vomiting, dyspepsia.

From the respiratory system: paradoxical bronchospasm, irritation of the mucous membrane of the oral cavity and pharynx (pharyngitis), cough.

On the part of metabolism: possible hypokalemia (may be a serious danger to the patient), reversible hyperglycemia.

Others: muscle cramps.

Instructions for use

Release form, composition and packaging


Aerosol for inhalation dosed, breath-activated, in the form of a white suspension, which, when sprayed onto glass, forms a white spot.

Excipients: ethanol, hydrofluoroalkane (HFA-134a).

200 doses - aluminum cylinders (1) - breath-activated aerosol inhalers, (1) - cardboard packs.

Clinico-pharmacological group: Bronchodilator drug - beta 2-agonist

Registration Nos.:


• aerosol for inhalation. dosed, breath-activated, 100 µg/1 dose: balloon 200 doses - P N014097/01, 04/17/07

  Dosage

  Adults and children over 12 years old Salamol Eco Easy Breathing is prescribed in doses of 100-200 mcg (1-2 inhalation doses) to stop attacks of bronchospasm. To control the course of mild asthma, it is recommended to prescribe 1-2 doses 1-4 times a day .; with moderate severity of the disease - in the same dosage in combination with other anti-asthma drugs. For the prevention of physical effort asthma, the drug is used 20-30 minutes before the load, 100-200 mcg (1-2 inhalation doses) per dose.

  Children from 2 to 12 years old development asthma attack, as well as to prevent asthma attacks associated with exposure to an allergen or caused by exercise, the recommended dose is 100-200 mcg (1 or 2 inhalations).

  The daily dose of Salamol Eco Easy Breathing should not exceed 800 mcg (8 inhalations).

  Instructions for using the inhaler

  Shake the inhaler several times before use. Then, holding the inhaler upright, open the lid. Take a deep breath, then tightly cover the mouthpiece with your lips. It must be ensured that the hand does not block the ventilation holes on the top of the inhaler and that the inhaler is in an upright position. Take a slow maximum breath through the mouthpiece, hold your breath for 10 seconds or as long as it is convenient. Then you need to remove the inhaler from the mouth and exhale slowly. After use, while continuing to hold the inhaler in an upright position, close the lid. If more than one inhalation is to be done, the lid is closed and after waiting at least one minute, the inhalation process is repeated.

  Cleaning the inhaler

  The upper part of the inhaler must be unscrewed and the metal cartridge removed. Then rinse the bottom of the inhaler in warm water and dry. Then insert the bottle into place. Close the lid and screw the top of the inhaler to its body. Do not wash the top of the inhaler. If the inhaler does not work properly, unscrew its top and manually press the can.

  Overdose

  Symptoms: nausea, vomiting, irritability, hallucinations, tachycardia, ventricular flutter, peripheral vasodilation, decreased blood pressure, hypoxemia, acidosis, hypokalemia, hyperglycemia, muscle tremor, headache.

  Treatment: drug withdrawal, cardioselective beta-blockers; if necessary, carry out symptomatic therapy. If an overdose is suspected, serum potassium levels should be monitored.

  special instructions

  In patients with severe or unstable asthma, the use of bronchodilators should not be the main or only method of therapy. The patient should be warned about the need to consult a doctor if the use of the drug Salamol Eco Easy Breathing in a standard dose becomes less effective or less prolonged (the effect of the drug should last at least 3 hours).

  Frequent use of salbutamol can lead to increased bronchospasm and various complications (up to a sudden death), and therefore it is necessary to take breaks of several hours between successive inhalations.

  An increase in the need for inhaled beta2-agonists with a short duration of action to control the symptoms of bronchial asthma indicates an exacerbation of the disease. In such cases, the patient's treatment plan should be reviewed and the issue of prescribing or increasing the dose of inhaled or systemic corticosteroids should be decided.

  Therapy with beta 2-agonists can lead to hypokalemia . Particular caution is recommended in the treatment of severe attacks of bronchial asthma, because in these cases hypokalemia may increase as a result of the simultaneous use of xanthine derivatives, corticosteroids, diuretics, and also due to hypoxia. In such situations, it is necessary to control the level of potassium in the blood serum.

  A can of Salamol Eco Easy Breath should not be pierced, disassembled or thrown into a fire, even if it is empty.

  Like most other aerosol inhalation products, Salamol Eco Easy Breathing may be less effective at low temperatures. When cooling the cartridge, it is recommended to remove it from the plastic case and warm it with your hands for several minutes.

  Application of the drug

  The drug is contraindicated for use during pregnancy. During lactation (breastfeeding) is prescribed only in cases where the expected benefit to the mother outweighs any potential risk to the child.

  Application for violations of kidney function

  The drug is contraindicated in renal failure.

  Application for violations of liver function

  The drug is contraindicated in liver failure.

  drug interaction

  Theophylline and other xanthines, when used simultaneously with salbutamol, increase the likelihood of developing tachyarrhythmias; and means for inhalation anesthesia, levodopa - severe ventricular arrhythmias.

  MAO inhibitors and tricyclic antidepressants increase the effect of salbutamol and can lead to a sharp decrease in blood pressure.

  With the simultaneous use of salbutamol enhances the effect of drugs with a stimulating effect on the central nervous system, side effects of thyroid hormones, cardiac glycosides.