Rutin ascorbic acid clinical use. Full analogues of the described drug in terms of active substances are medicines. Interaction with drugs of other groups

Askorutin is a domestic complex drug belonging to the group of vitamins, intended for the prevention of vitamin C and P deficiency and which is often prescribed for diseases of the blood vessels. In addition, this vitamin preparation is used to reduce immunity, allergies and some other health problems.

What is useful askorutin description and composition

The active substances of this drug are vitamin C and vitamin P. Each tablet contains 50 mg of ascorbic acid and rutoside (rutin).

The excipients include talc, potato starch, calcium stearate or glucose, sugar, calcium stearate. The specific composition of excipients for each manufacturer may vary.

Rutin belongs to natural flavonoids, which are considered one of the most powerful antioxidants. This compound helps to reduce the permeability and fragility of capillaries, reduces increased blood clotting, strengthens the immune system, and protects the body from viruses and bacteria.

Ascorbic acid or vitamin C also belongs to the group of vitamins with antioxidant properties. It takes part in many metabolic processes and has a generally positive effect on the musculoskeletal system and blood vessels. Vitamin C helps bind and remove toxins from the body, is involved in the production of collagen fibers and connective tissue.

Askorutin is available in the form of tablets packed in jars or blisters of 10, 18, 50 or 100 pieces, depending on the manufacturer. Tablets have a slightly greenish tint.

The trade name of this vitamin is Ascorutin. International - ascorbic acid + rutoside.

What helps askorutin pharmacological action

Taking this vitamin can help several problems. It helps improve:

Redox processes;

carbohydrate metabolism;

Synthesis of natural steroid hormones;

tissue regeneration;

blood clotting;

blood microcirculation;

The body's resistance to adverse conditions.

This drug participates in the restoration and synthesis of connective tissues.

Its use helps:

Reduce the effect of radiation;

Strengthen the walls of blood vessels;

Reduce the fragility and permeability of small blood vessels;

Increase immunity;

Improve the elimination of toxins from the body.

All these properties of a cheap domestic vitamin are important during the recovery period after the flu, acute respiratory infections and some other diseases.

Some doctors prescribe it during the recovery period for cancer patients in order to normalize the vitamin balance and improve the patient's condition.

The drug is of particular importance for patients suffering from venous insufficiency, which are accompanied by pain and swelling of the extremities, inflammation of the blood vessels.

Askorutin indications for use

In the official instructions for the drug, the main indication for use is:

Vitamin C and rutin deficiency;

Capillary lesions caused by the action of drugs from the group of coagulants and salicylates.

In addition, ascorutin is used in the complex treatment of certain diseases that are accompanied by damage and impaired vascular permeability, such as:

Hemorrhagic diathesis;

Hemorrhage in the retina;

Rheumatism;

Septic endocarditis;

Glomerulonephritis;

Allergy;

Scarlet fever;

Typhoid fever;

Superficial thrombophlebitis;

Trophic disorders or ulcers;

Varicose veins, accompanied by pain and swelling;

Chronic venous insufficiency;

Hypertension;

Arachnoiditis;

Radiation sickness.

The use of this drug allows you to:

Restore the integrity of damaged capillaries and improve their condition;

Increase the body's resistance to viral and colds;

Eliminate residual symptoms of influenza and acute respiratory diseases;

Replenish the body with ascorbic acid and vitamin R.

How to take ascorutin

Askorutin, according to the annotation, is taken during or immediately after a meal, washed down with water. Dissolving, chewing it is not recommended. The explanation for this is simple - ascorbic acid can have a detrimental effect on tooth enamel and gastric mucosa.

He drinks plain water. It is strongly not recommended to use mineral alkaline water for this, since such water neutralizes vitamin C.

The specific dosage, the number of doses per day, the course of administration depends on the disease and purpose of use, the age of the patient, his condition and is prescribed by a doctor. On average, for an adult, the intake rate is 1 tablet, taken two to three times a day. Duration of admission is 2-3 weeks. Sometimes appointments are made up to a month.

How to take askorutin for adults

For prevention, adults are prescribed 1 tablet taken once or twice a day.

For treatment or in complex therapy with other drugs, it is usually prescribed 1-2 tablets three times a day. The attending physician prescribes a specific rate.

Askorutin how to take children

For children, this vitamin is prescribed only by a pediatrician, taking into account all the indications and pathologies of the child, not earlier than from the age of 4. At an earlier age, the drug is not recommended.

The prophylactic dose can be from half to one tablet taken once a day.

For treatment, a specific rate, frequency and duration of administration is prescribed by a doctor depending on the disease. The duration of admission is three to four weeks.

A child who cannot swallow a tablet should be crushed and dissolved in water.

Reception for children, as well as for adults, only during meals or immediately after feeding.

For adolescents, the vitamin is prescribed in the same dose as for adults.

Can Ascorutin be taken during pregnancy?

Reception of ascorutin in the first trimester (up to 12-13 weeks) is prohibited, as it can affect the development of the fetus. Starting from the 2nd and 3rd trimester, ascorutin is prescribed for certain indications. Only a doctor should prescribe it. During this period of pregnancy, it is prescribed to improve the elasticity of blood vessels and capillaries and as a prophylactic. In addition, taking ascorutin may reduce the risk of uterine bleeding during childbirth.

Take it, as a rule, 1 tablet two or three times a day with or immediately after food.

It is forbidden to use it simultaneously with other vitamin preparations.

During lactation, ascorutin is prescribed by a doctor according to the relevant indications in a young mother.

Askorutin for varicose veins

With varicose veins, it is usually taken in combination with other drugs. Taking ascorutin helps strengthen the walls of the veins, reduces and prevents swelling of the lower extremities, and reduces the risk of blood clots.

Askorutin for gout and diseases of the musculoskeletal system

Askorutin in such diseases can be prescribed in complex treatment. It has an indirect effect on improving blood circulation in damaged joints and spinal discs, improves the delivery of nutrients to damaged tissues and its regeneration.

Askorutin for diabetes

As part of a vitamin preparation, some manufacturers may contain sugar as an auxiliary substance, which is contraindicated in patients with diabetes. Therefore, before taking it yourself, be sure to consult your doctor.

But diabetics often have a whole “bouquet” of other concomitant diseases, in which the intake of ascorutin could be a prophylactic or improve the condition.

So, it is able to improve blood microcirculation in the retina of the eyes and prevent the development of retinopathy, which often happens in such people.

In addition, it improves the excretion of glucose from the blood, helps to reduce blood cholesterol levels and normalizes the function of the pancreas.

In addition, the drug has preventive properties for colds and viral diseases.

Based on this, it should be noted that ascorutin may be useful for such patients. Therefore, the pharmaceutical industry produces a sorbitol-based drug called Ascorutin D specifically for such patients.

Taking a vitamin remedy is prescribed only by a doctor. The daily norm is usually 1 tablet twice a day for the purpose of prevention. The duration of admission is from three to four weeks.

How to take askorutin to strengthen the walls of blood vessels

Askorutin to strengthen the walls of blood vessels is prescribed in complex treatment. The rate and frequency of administration is prescribed by the attending physician, depending on the severity of the disease. As a medicine in this condition, treatment with ascorutin alone will not bring any benefit and the disease cannot be cured.

Ascorutin for nosebleeds

Askorutin with nosebleeds can strengthen the walls of blood vessels, reduce their fragility. It is prescribed together with other drugs.

Often, ascorutin is prescribed to children with such a pathology. It should be noted that children are much more likely to suffer from a runny nose, which in turn can provoke nosebleeds. Taking the drug in this case can increase the child's defenses and reduce the likelihood of colds.

It is strictly forbidden to prescribe it to yourself or your child without consulting a doctor. In addition to positive qualities, it has contraindications and side effects.

Askorutin with heavy periods

For women who constantly suffer from heavy and prolonged periods, a gynecologist may prescribe a course of this vitamin. They begin to take it three to four days before the onset of menstruation. The duration of admission is 10 days or is negotiated by the doctor specifically for each patient. The dose and frequency of administration is also prescribed by the gynecologist.

It must be remembered that other health problems may be the cause of this situation. Therefore, you can not drink ascorutin on your own. It is better to pass the appropriate examination.

Askorutin in cosmetology

Our skin needs vitamins. Often this vitamin can be found in cosmetic face masks. It helps with pigmentation, acne, rosacea.

With rosacea, this vitamin can be taken orally and masks can be made with it.

The easiest way is to make a homemade face tonic. To do this, you need to brew 1-2 tablespoons (or 1-2 bags) of chamomile herbs with 500 ml of boiling water. Insist and filter.

Grind the ascorutin tablets into powder and dissolve in the cooled infusion. Stir until completely dissolved.

The use of such a tonic will narrow the pores, relieve inflammation and improve microcirculation in the skin. Apply once or twice during the day.

Read

Latin name: Ascorutinum ®
ATX code: C05CA51
Active substance: acid ascorbic, rutoside
Manufacturer: ValentaPharmaceutics (Russia)
Pharmacy leave condition: Without recipe

Combined vitamin preparations are designed to eliminate the deficiency of essential substances. Despite the fact that they are dispensed without a prescription and contain an annotation, a preliminary consultation with a doctor is required, who will tell you, for example, what Askorutin is used for, how to drink it to an adult patient and a child. This drug has an effect on metabolism and digestion, contains rutazid and ascorbic acid. But its main purpose is to strengthen the capillary walls. It takes part in oxidation and reduction, has antioxidant and radioprotective properties, and copes well with colds. Askorutin is often prescribed during pregnancy, but not in the first months. This is due to the fact that at the initial stages of fetal development, enhanced vitamin nutrition is not recommended.

Indications

The complex is suitable for the treatment and prevention of the following diseases and conditions:

  • Vitamin C avitaminosis
  • Hypovitaminosis of quercetin and vitamin P
  • Prevention of SARS epidemics
  • During and after long-term use of anticoagulants or salicylates
  • Infectious pathologists, including those with cough (scarlet fever, measles, influenza)
  • Hemorrhagic vasculitis
  • Ascorutin is effective for varicose veins
  • Capillary toxicosis
  • Couperose
  • Rheumatism
  • Exposure to radiation
  • Nosebleeds
  • Retinal damage
  • In gynecological practice, Ascorutin is prescribed for menstruation
  • Endocarditis
  • damage to the renal glomeruli
  • allergies
  • Serous inflammation of the arachnoid
  • Hematological pathologies with platelet insufficiency.

Compound

The drug is available in only one form - tablet. The drug contains two effectively interacting main active elements: ascorbic acid and rutazid. In addition, it includes additional components. These are starch, calcium stearate, talc and sugar. Each of them is intended for the manufacture of Ascorutin vitamins and shaping the tablets. Substances act as preservatives, stabilizers and emulsifiers.

Pharmacological properties

The vitamin complex is a combined remedy. If you are interested in the question of what Askorutin tablets help from, you should find out information about their composition. First of all, it is ascorbic acid, which is one of the most important elements required for the normal state of connective and bone tissue. The substance looks like a white powder, highly soluble in water and alcohol.

It takes part in the synthesis of collagen, is responsible for the production of serotonin from tryptamine. The production of thyroid hormones and the supply of glucose for cellular nutrition depend on it. Also, the drug Askorutin affects the production of catecholamines and the conversion of cholesterol into bile acids. Vitamin with the participation of cytochines is required for detoxification in parenchymal cells. Allows the use of Askorutin during pregnancy, the fact that it inhibits the release of histamine components, inhibits the formation of mediators of inflammation and allergic reactions.

After oxygen enters the blood, free radical compounds are formed, the action of which is inhibited by ascorbic acid, thereby stopping the aging process. In low doses, its use for coughs and colds is not justified, but since the substance synthesizes interferon, it acts as an immunomodulator. What is important for preventive purposes. The element improves the absorption of iron ions, so it is advisable to prescribe Askorutin for adults and children.

In patients taking the complex, there was resistance to infections, a decrease in the need for pantothene and folic acid. Since the vitamin maintains normal capillary permeability and the keloid state of the intercellular substance, the production of hyaluronidase decreases. Therefore, Askorutin plays an important role in strengthening blood vessels. It activates proteolytic functions, metabolizes amino acids and pigments, and is responsible for the accumulation of glycogen compounds in the liver.

Another active element of the drug is rutoside. It is a glycosidic flavonoid derivative of quercetin with antioxidant properties. Thanks to its lipophilic action, it freely penetrates through cell membranes, contributing to their stability. It prevents wall permeability by inhibiting lipoxygenase. This mechanism is aimed at preventing premature aging and tissue death. Usually, in the hot season, the heart works in an enhanced mode, moving blood faster, so nosebleeds can occur with weak vessels. To prevent this phenomenon, it is important to take the remedy in the summer.

Vitamin penetrates into nerve fibers, where it affects receptor reactions, thereby reducing the release of inflammatory mediators. Askorutin is prescribed for children and adults for the purpose of accelerated cell regeneration, as a sedative, analgesic and antiallergic agent. Rutin provides the following effect:

  • Helps control hormone levels
  • Improves the condition of the vascular walls
  • Has anti-inflammatory activity
  • Prevents thrombosis
  • Suspends the aging process

Since the active substances can accumulate in the body, especially with a long course, it is necessary to check with the therapist or pediatrician how to take Askorutin during pregnancy and children. The drug is well absorbed and penetrates into all tissues and fluids. Excreted through the kidneys. Its use allows you to quickly replenish the increased consumption of nutrients. Studies have shown that, by strengthening the capillary walls, Askorutin during pregnancy reduces the risk of developing hemorrhages and oxygen starvation of the fetus. But it is prescribed only in case of indications. The use of any vitamin complex should be previously discussed with the doctor.

Since the circulatory system of the placenta is characterized by weakness and low elasticity, Ascorutin during pregnancy reduces the risk of developing hemorrhages.

Release form

The drug is produced in the form of small tablets of a yellowish-green hue, with a dividing line in the center. They are packed in 10 units in aluminized blisters with a transparent propylene surface or in plastic bottles. They do not have a smell, they have a pleasant taste, so they can be absorbed. A pack of cardboard includes one bank or 3-6 plates and Askorutin instructions for use. A small but significant bonus is their low price.

Application methods

Cost: tab. 50 mg No. 30 - 35-45 rubles. No. 50 - 55-65 rubles.

Before starting treatment, it is necessary to consult a doctor who will tell you how to drink Askorutin under different conditions and depending on age. Tablets should be swallowed after meals, the dose for adults is 1-2 units per day for prevention, for therapeutic purposes, 2 pieces are prescribed three times a day. The average course duration is 3-4 weeks. If necessary, after a monthly break, treatment can be continued.

The dosage of Askorutin and the method of application in childhood is to use half a tablet once every 24 hours to prevent the development of diseases and deficient conditions. Babies older than 3 years of age are prescribed for therapy one piece 2-3 times a day. But constant monitoring and control of the functioning of all systems is required. It is not recommended to drink liquid with alkaline content, as the absorption of the composition is reduced.

Application during pregnancy

Do not prescribe the drug in the 1st trimester, as the risk of vitamin oversaturation increases. The rest of the time and during lactation, the reception is standard.

Contraindications

The complex of vitamins is prohibited for use in the following diseases and conditions:

  • High susceptibility to the components of the composition
  • Impaired blood clotting
  • Thrombophlebitis and existing blockages
  • Diabetes
  • Severe kidney damage
  • Gout
  • The presence of oxalate stones in the kidneys
  • Tubulopathies
  • Decreased concentration of potassium ions
  • Violation of the process of splitting food
  • Fructose intolerance.

Combination with other medicines

Before taking the drug, you need to get information about its interaction with various medicines:

  • Decreased absorption occurs due to simultaneous use with alkaline solutions and acetylsalicylic acid
  • Combines well with penicillin and iron-containing medicines
  • Functions decrease when using anticoagulants, heparin, aminoglycoside, sulfanilamide antibiotics
  • The risk of side effects increases with the simultaneous appointment of salicylates and tetracyclines
  • With a long course, the concentration of non-steroidal anti-inflammatory compounds and glycosides increases, which should be taken into account.

Adverse reactions

Since the main active ingredients of the drug are similar to natural metabolites, negative effects are rarely observed. In some cases, the following effects may appear:

  • On the part of digestion - dyspeptic disorders, irritation of the mucous membrane, heartburn.
  • Cardiac and vascular system - increased blood pressure, microangiopathy, muscular dystrophy. hypertensive crises.
  • Nervous system - increased excitability, sleep disturbance, irritability.
  • Hematopoiesis - thrombocytosis, leukocytosis.
  • Metabolic processes: hyperglycemia, fluid retention and sodium elements in the body.
  • The use of alcoholic beverages does not have a particular effect on the therapeutic properties of the complex, but it can provoke a number of adverse reactions, therefore Askoriutin and alcohol are incompatible.

Overdose

Exceeding the recommended amount of the drug is fraught with inhibition of the function of the pancreatic gland and a violation of the insular mechanism. Itching and rashes on the skin may appear, symptomatic hypertension may develop. Treatment in such cases is based on clinical signs. The patient undergoes sanitation, gastric lavage. Sorbents are prescribed for it and measures are taken to reduce the concentration of vitamins.

Storage rules

The drug can be used for three years. It should be kept out of the reach of light and moisture. Access for children should be restricted.

Analogues

There are a number of drugs whose action is identical to the activity of Askorutin:

Troxevasin

Manufacturer: BalkanPharma (Bulgaria)

Price: caps 300 mg No. 100 - 600-650 rubles.

Angioprotector, the main substance of which is troxerutin. Despite the difference in active ingredients, there is an important similarity between Askorutin and Troxevasin: both drugs are responsible for the condition of the walls of blood vessels. The latter drug is able to narrow the gaps between endothelial cells by changing their matrix. It has an anti-inflammatory effect, reduces trophism and reduces swelling. With varicose veins, discomfort and stiffness are eliminated. With hemorrhoids - pain and bleeding.

The product is produced in the form of gelatin capsules of a bright yellow hue, enclosed in translucent blisters. The pack is white, with lilac cubes as decoration. It includes 10 plates. The manufacturer also offers a composition for external use in the form of a light gel.

Advantages:

  • Available in two forms
  • It relieves pain with varicose veins and hemorrhoids.

Flaws:

  • High price
  • May cause a number of adverse reactions.

Rutin

Manufacturer: Thompson (USA)

Price: tab. 500 mg No. 60 - 800-900 rubles.

The drug contains only one main active ingredient - rutazid. It is effective for hypovitaminosis, vascular permeability, hemorrhagic diathesis. It is also prescribed for rheumatism, endocarditis, hemorrhages. It acts as an angioprotector, reduces swelling, improves hematopoiesis and rheology. As a rule, it is recommended to drink it together with vitamin C, since the combination of these compounds restores the concentration of useful substances to the maximum and promotes cell regeneration. Flavonoid increases the production of hyaluronic acid and simultaneously inhibits the synthesis of hyaluronidase.

The manufacturer offers the drug in tablet form. The medicine is packaged in dark brown glass bottles with an aluminum crimp cap and a polypropylene stopper. It has a bright yellow tint and a pleasant taste. Has no smell. The drug is contraindicated in the 1st trimester of pregnancy and with increased sensitivity to vitamin C.

Advantages:

  • Adverse reactions are very rare
  • Slows down the aging process.

Flaws:

  • Sold in one form only
  • High price.

The instruction is necessary for patients to familiarize themselves with the information, both about the Ascorutin tablets themselves, and about their purpose and use. Here you can also learn about analogues, prices and reviews about the drug.

Form, composition, packaging

The release form of Askorutin is a tablet that has a light color in greenish-yellow tones. It contains 50 milligrams of the substance Rutozid and ascorbic acid. The preparation is supplemented with the necessary proportions of talc, sugar, calcium stearate and potato starch.

The packaging of this drug is a cardboard box, where, in turn, packed in polymer jars (30 or 50 pieces) or contour blisters with cells of the tablet are placed. The blister contains ten pills. In a box, you can put one such jar or five blister records.

Terms and conditions of storage

The drug can be stored for three years in dry conditions, where the air temperature is constant, not exceeding 25 degrees and there is protection from direct sunlight. Babies are not allowed to take the drug.

Pharmacology

Being a combined drug, this drug is a pharmaceutical complex of a vitamin and a useful biologically active component that is included in the tablet. The combination of these components helps to strengthen the vascular walls of the bloodstream due to its ability to reduce capillary fragility and permeability.

Also, due to its influence, it becomes possible to inhibit the aggressiveness of platelets, which serve as the main elements of cells in the blood coagulation system, and the suppression of nosological units occurs, where the formation of blood clots takes place.

Pharmacokinetics

After ingestion, the Ascorutin tablet undergoes fairly rapid absorption in the digestive tract. Entering the bloodstream, the components of the drug are immediately distributed throughout the body, passing through their inherent metabolism in all tissues and organs. Each received metabolic product is excreted in the urine and bile.

Askorutin indications for use

The range of application of Ascorutin is quite wide. It is recommended for use in the implementation of:

  • preventive measures for beriberi;
  • therapeutic measures for the lack of vitamins in the body;
  • elimination of capillary lesions due to exposure to other medications (salicylates, indirect anticoagulants);
  • as part of complex treatment to eliminate vascular permeability disorders in scarlet fever or measles, hemorrhagic diathesis, typhus typhus, radiation disease, thrombocytopenic purpura, retinal hemorrhages, allergic diseases, septic endocarditis, arachnoiditis, capillary toxicosis, glomerulonephritis;
  • prevention and elimination of flu and cold symptoms.

Contraindications

  • with a high degree of sensitivity of the patient to the composition of the drug;
  • for children up to four years of age;
  • with increased blood clotting;
  • during pregnancy of the first trimester;
  • in the presence of thrombophlebitis, as well as those with a tendency to thrombosis;
  • with fructose intolerance;
  • those who suffer from diabetes mellitus;
  • with severe severe kidney disease;
  • with the identified galactose-glucose malabsorption syndrome;
  • those who suffer from gout, cystinuria, oxalaturia, hypokalemia or urolithiasis.

Askorutin instructions for use

Take the drug inside. It is not necessary to drink Ascorutin tablet with water of mineral or alkaline composition, otherwise the absorption capacity in the digestive tract will worsen in the components of the drug.

Dosing is selected individually based on age and other parameters, as well as based on clinical analysis data and on the need for prescription.

For the purpose of prevention, an adult patient is prescribed 1 or 2 tablets / 1p / day;

For therapeutic purposes, take 1 or 2 tablets twice or thrice daily.

The dosage can be changed as directed by the doctor.

The decision to repeat the treatment course is also made by the treating specialist.

Ascorutin during pregnancy

During pregnancy, Askorutin is not prescribed during the first trimester, since there is a high risk of pathological conditions due to oversaturation with vitamins of group C. Askorutin is not used in conjunction with other complexes of mineral and vitamin supplements.

In the event of a critical situation, a woman is allowed to prescribe the drug on a tablet up to three times a day.

Askorutin for children

Children after the age of four can use Ascorutin half a tablet as a prophylactic for various pathologies.

For treatment, children are prescribed 0.5 or 1 piece several times a day for about a month of admission. A more accurate dosage and duration of therapy is calculated by the doctor at the time of appointment.

Adolescents may use to take the adult dose after they have been fully monitored to avoid the consequences of improper treatment.

Ascorutin for bleeding

Being a fairly effective remedy for eliminating many types of bleeding (nose, from the gums, uterine, intestinal, hemorrhoidal), the drug still does not belong to the means that the ambulance uses.

Ascorutin during menstruation

During menstruation, when they are plentiful and long, Askorutin can be prescribed by a doctor.

Start of administration: a few days before the cycle begins. The duration of admission is up to ten days. But it should be borne in mind that taking the drug on its own is strictly prohibited. First, the gynecologist must find out the cause of this phenomenon. If a hormonal imbalance is detected, then Askorutin will not cope with the problem without appropriate drugs.

Side effects

Although side effects when taking this drug are noted very infrequently, they still take place, manifesting themselves as follows:

CNS

Headaches may develop, the vigor-sleep regimen may be disturbed, the excitability of the central nervous system may increase, and the patient's fatigue may increase.

Circulatory system

Taking the drug is fraught with the development of thrombocytosis, neutrophilic leukocytosis, increased production of platelets and red blood cells, hypertrobinemia.

Cardiovascular area

There is a threat of development of microangiopathy, hypertensive crisis, dystrophy of the heart muscle and disturbances of natural processes in tissue trophism.

digestive tract

Symptoms of heartburn, vomiting and nausea, as well as the development of diarrhea. Irritation of the gastrointestinal mucosa is not excluded.

There were some allergic disorders (in the form of rash, itching, angioedema and others) in nature, as well as in terms of metabolic processes. What can be expressed by malfunctions in the work of the pancreas, retention of sodium and excess fluid in the body, the state of hypervitaminosis C, as well as a deviation from the metabolic norms for zinc and copper with regard to their properties in this area.

Overdose

In case of an overdose of Ascorutin, malfunctions in the functioning of the kidneys and pancreas are observed. Overdose symptoms may include:

  • in the form of pain in the epigastrium;
  • headaches;
  • bouts of vomiting accompanied by constant nausea;
  • high pressure;
  • profuse rash and itching in the area of ​​​​the bends of the elbows and knees, as well as on the chest and abdomen;
  • thrombus formation;
  • overexcitability of the nervous system.

Symptomatic treatment is used as a treatment for this condition. There is no special agent. The patient should be washed out of the stomach and offered to take sorbents.

Drug Interactions

The drug is absorbed much worse than usual if it is taken simultaneously with acetylsalicylic acid, contraceptives for oral administration or alkaline drinking. The same can be said about fruit and vegetable juices.

Iron preparations and penicillin increase the absorption of Ascorutin tablets.

The effect of the drug Ascorutin will be reduced if it is taken together with heparin, vitamin B, indirect anticoagulants, sulfanilamide preparations, as well as aminoglycoside antibiotics.

An increase in the serum concentration of drugs such as salicylates, tetracyclines, ethyleneestradiol, benzylpenicillin occurs when they are combined with ascorbic acid, with the risk of developing side effects of these drugs.

Long-term use of Ascorutin with concomitant use of cardiac glycosides, NSAIDs or antihypertensive drugs can significantly increase the effect of these drugs. When combining such drugs, you should be extremely careful, otherwise the consequences can be disastrous.

Additional instructions

The high effectiveness of Ascorutin tablets is noted for eliminating a cosmetic skin defect called rosacea, when the blood circulation of the skin of the face is disturbed and, as a result, an unnatural redness of a local nature appears on the face in the area of ​​the nose, cheeks and forehead.

Askorutin analogues

The active ingredients of Askorutin are present in its analogues called Prophylactin C, Askorutin UBF and Askorutin D.

The drug also has drugs similar in effect to therapeutic drugs. These are Angiovit, Aescusan, Venarus, Cyclo 3 fort; Detralex.

Each of the drugs, if necessary, is allowed to replace the treatment with Askorutin.

Askorutin price

The drug is basically not expensive, but its cost should be specified when buying. Its average price, according to the latest data, did not exceed 50 rubles for a jar of tablets in the amount of 50 pieces.

Askorutin reviews

Being, in fact, a multifunctional drug, Ascorutin collects quite a lot of feedback on its use. Many note its availability and reasonable cost with such a wide range of pharmacological properties.

The number of grateful reviews about the drug is especially high in the topic of treatment of vascular pathologies, varicose veins, and even getting rid of pigmentation.

There are a lot of reviews, so we will voice the most recent ones.

Tamara: I used to suffer from nosebleeds often. On the advice of my mother, I bought Ascorutin, which she tested in many areas. I must say, I was treated with it at least ten years ago, and the effect of treatment still remains. Since then, I am no longer afraid that the blood from the nose will run in the most inappropriate place. Now, having convinced herself of the effectiveness of the remedy, she herself began to advise her friends.

Svetlana: When I was undergoing procedures on the retina using a laser, I got acquainted with the drug Askorutin. The first impression was great. The medicine has done exactly what it was supposed to do. In addition, its cost cannot but rejoice. Later, having already completed a treatment course to restore retinal vessels, I noticed a lot of positive qualities for myself: this is the absence of side effects when taken and the ability to treat varicose veins, which is also extremely useful for me. In a word, a storehouse of vitamins and a solid health benefit, especially for women. I recommend to get acquainted with the drug.

Julia: My mother and grandmother suffer from varicose veins and I had to think about this disease, because after the birth of a child, my legs blossomed with spider veins. Recently, my doctor, who previously prescribed me the drug Askorutin as a means for the prevention of acute respiratory viral infections and influenza, advised me to take it for the legs if side effects are not bothering me. I decided to follow his advice. I'll look at the result when I finish the course. Today I can only say that my legs began to hurt less and the cramps that tormented me since pregnancy became less pronounced. In general, the drug is praised, I think I will also join.

The combination of two substances in the composition of one drug - vitamin C and the flavonoid rutoside - made it possible to create the drug "Ascorutin". Indications for the use of a therapeutic and prophylactic agent are due to the effect that its components have together and each separately. They take the drug "Askorutin" for hypo- and beriberi, to strengthen the walls of blood vessels and treat a number of diseases.

Tablets "Ascorutin". The composition of the drug

The drug belongs to the pharmacotherapeutic group "capillary-stabilizing agents (capillary-protective)". One Ascorutin tablet contains 50 mg of vitamin C and 50 mg of rutoside (rutin). Excipients are also present: sugar, stearic acid, potato starch and talc. The greenish or yellow color of the tablets interspersed is due to the presence of a component of plant origin - rutoside.

The diverse pharmacological effect of the combined drug is due to the properties of the two main components - vitamin C (L-ascorbic acid, ascorbate) and rutin (rutoside, sophorin). Ascorbic acid is an organic substance, its formula is C 6 H 8 O 6 . The compound is required by the cells of living organisms for the implementation of metabolic processes, a deficiency leads to scurvy. Vitamin C is essential for regulating the oxidation process and is a powerful antioxidant. The plant pigment rutin is a bioflavonoid, its composition reflects the formula C 27 H 30 O 16. One of the names - sophorin - appeared due to the significant content of this substance in Japanese Sophora. The compound has the properties of vitamin P, strengthens blood vessels.

The drug "Askorutin". Indications for use

The combination of rutin and ascorbic acid tablets allows for progress in the treatment of capillary permeability and fragility. The drug "Ascorutin" not only has a positive effect on the strength of blood vessels. It has anti-inflammatory and antioxidant properties. Indications for its use:

  • hypo- and avitaminosis C and P;
  • increased vascular permeability;
  • hemorrhagic diathesis;
  • allergies;
  • capillary toxicosis;
  • hemorrhages in the retina;
  • glomerulonephritis;
  • septic endocarditis;
  • rheumatism;
  • infectious diseases (measles, scarlet fever, typhus).

Useful properties of routine

In 1936, Nobel laureate A. de Saint-Györgyi found that rutoside, which he called vitamin P, eliminates excessive permeability and fragility of blood vessels. Further studies have provided data on the anti-inflammatory properties of the substance, its ability to treat chronic venous insufficiency. This is the name of the condition in which the veins lose their ability to effectively pass blood from the legs to the heart. The consequences of this are varicose veins, swelling and nocturnal leg cramps.

As part of the Ascorutin preparation, rutoside maintains the health of blood vessels, its beneficial effect on capillaries is especially great. Vitamin C works together with the routine, which allows you to achieve an enhanced therapeutic effect. The drug can be used in late pregnancy and lactation. When symptoms of side effects caused by radiation therapy appear, Ascorutin tablets are also prescribed. Indications for use include drug-induced capillary lesions caused by long-term use of anticoagulants, such as salicylates. The drug helps to eliminate swelling and pain, trophic disorders in people suffering from venous insufficiency. Taking Ascorutin tablets reduces the risk of paresthesia and seizures.

Vitamin C and antioxidant protection

Why were rutoside and ascorbic acid combined as part of the Ascorutin preparation? Indications for the use of a therapeutic and prophylactic agent take into account the synergism of active substances, their joint effect on the causes of the disease. Ascorbin and rutin take an active part in the redox reactions of cells. Studies have shown that vitamin C is the first line of antioxidant defense against free radicals. These are particles in the structure of which disturbances have arisen, and they seek to regain their stability by destroying neighboring molecules. Free radicals start a chain of reactions that have a detrimental effect on the cells of the body. They can damage the inner walls of the arteries, weaken the immune system. Vitamin C prevents free radical damage to cells.

Rutin enhances and complements the action of ascorbin

Pathological processes caused by free radicals can cause cancer, cardiovascular disease, diabetes, memory and vision impairment, and premature aging. It has been proven that rutin increases the absorption of vitamin C, which, in turn, more actively absorbs free radicals in the presence of a bioflavonoid. Ascorbic acid helps to eliminate toxins from the body, it plays one of the key roles in maintaining immunity. Vitamin C also has an antihistamine effect, which is important in preventing allergic diseases.

Contraindications and side effects

Hypersensitivity to the components of the drug "Ascorutin" is a contraindication for its use. This warning refers to increased blood clotting, thrombophlebitis, the body's tendency to form blood clots. The list of contraindications includes such serious diseases as diabetes, gout, urolithiasis. In the first trimester of pregnancy and children under 3 years of age, Ascorutin tablets are also not prescribed. Side effects are observed while taking the drug with liquids that have an alkaline reaction. The use of freshly squeezed juices reduces the absorption of ascorbic acid. Taking the medicine can change the results of laboratory tests (blood bilirubin levels and transaminase activity). There is no information about the effect of the product on people driving vehicles.

Interaction with other drugs

Taking Ascorutin tablets leads to an increase in the absorption of a number of substances in the body. This group includes the antibiotic "Penicillin" and iron. Ascorbic acid reduces the effectiveness of antibiotics, indirect anticoagulants and heparin. Simultaneous use with aspirin, oral contraceptives leads to a decrease in the absorption of the components of the drug. The use of Ascorutin tablets together with acetylsalicylic acid, Tetracycline increases their concentration in the bloodstream. Do not prescribe a long-term intake of rutin in parallel with cardiac glycosides (over 4 weeks). The same rule applies to non-steroidal anti-inflammatory drugs and drugs that lower blood pressure. Rutin can enhance their influence.

Dosage and administration

Ascorutin tablets should be taken orally after meals, swallowing them and drinking water. Treatment for therapeutic purposes:

  • adults - 2-3 times a day, 1 tablet;
  • after 3 years of age - 2 times a day, 1 tablet.

For preventive purposes:

  • adults - 2 times a day, 1 tablet;
  • children over 3 years old - 1 tablet per day.

The course of treatment is from 3 to 4 weeks. The doctor determines the duration of admission, based on the nature of the disease and the effect of the drug "Ascorutin" on the patient's condition. Overdose can lead to headache and nausea, vomiting, diarrhea. Excessive doses also cause blood clots and blood pressure spikes. In these cases, symptomatic treatment is used.

With daily stress, great physical, mental stress, the human body gradually wears out. People begin to notice premature signs of aging, suffer from dysfunction of internal organs and their systems. For this reason, they need vitamin complexes that improve the general condition of the body. "Ascorutin" is a combined vitamin preparation that compensates for the lack of ascorbic acid and rutin in it. Before using it, you need to study the instructions for using the complex, consult with a specialist.

Instructions for use

The manufacturer of this complex is the Kyiv Vitamin Plant, PJSC, located in the city of Kyiv in Ukraine.

Release form, composition

"Ascorutin" is available in tablet form. It can be taken not only inside. Often the tool is used to make tonics, face masks for certain diseases. Most often, the tablets have a greenish or yellowish tint. Cardboard packages of "Ascorutin" contain blisters of ten, fifty, one hundred pills, as well as jars of glass or polymers containing thirty or fifty pills.

The main components of the drug are:

  • ascorbic acid (vitamin C) - 50 mg;
  • rutin (vitamin P) - 50 mg.

Auxiliary substances in the composition of the complex are:

  • potato starch - 38.7 mg;
  • calcium stearate - 2.1 mg;
  • sugar - 185.7 mg;
  • Povidone-K25 - 3.5 mg.

Beneficial features

The benefits of using Ascorutin are:

  • decrease in permeability, fragility of capillaries;
  • inhibition of aggression of platelet cells;
  • prevention of the occurrence of a state of increased thrombosis;
  • removal of harmful structures that enter the body from the outside;
  • providing a powerful anti-inflammatory effect;
  • strengthening of the vascular walls.

In addition, the use of the drug allows you to maintain the cardiovascular system and digestive organs in a normal, functioning state.

Indications for appointment

The main indications for which the Askorutin complex is prescribed are:

  • hypovitaminosis, avitaminosis of vitamin substances of group P, C;
  • diseases accompanied by increased fragility of capillary tissues;
  • scarlet fever;
  • measles;
  • typhus;
  • rheumatic pains;
  • septic endocarditis;
  • vasculitis of hemorrhagic type;
  • toxic infections of capillary tissues;
  • radiation type disease;
  • eye hemorrhages;
  • nosebleeds in children;
  • prevention of the destruction of the vascular walls after prolonged use of drugs that have an anticoagulant, salicylate nature;
  • prevention of the development of influenza and other infectious diseases.

It is highly undesirable to start taking this complex on your own, since side effects may occur, which will significantly worsen the human condition.

Contraindications

The appointment of "Askorutin" is not carried out if a person has certain health problems. These include:

  • allergy to the components of the complex;
  • the first three months of pregnancy;
  • belonging to the children's age group under three years;
  • diabetes;
  • urolithiasis disease;
  • gout;
  • thrombophlebitis;
  • increased coagulability of human genetic material.

If it is used, despite the presence of contraindications, a person's condition can deteriorate dramatically, for example, the level of sugar in the genetic material in type 2 diabetes will increase. It is also important to observe the correct dosage when taking the tablets, so as not to become a victim of side effects.

How to use?

"Askorutin" is useful for children, as well as men and women. It is prescribed in certain situations, and therefore it is important to remember to follow the basic rules for using the remedy. You can find out if this drug is needed in this individual situation by consulting with a specialist.

During pregnancy

Do not forget that Askorutin is contraindicated in pregnant women in the first trimester. At this time, the laying and formation of the main vital organs of the fetus occurs, and therefore there is a risk of developing complications of mental and physical development. For this reason, it is recommended to refrain from using the vitamin during this period.

During the second, third trimesters, the complex is prescribed to prevent the development of infectious, viral diseases. Often it is prescribed to future women in labor, who may have uterine bleeding during childbirth. In the event of spider veins, the risk of developing varicose veins in the legs, the indicated complex is also prescribed. In any case, the dosage, the rules of use are set by the specialist leading the pregnancy.

To strengthen blood vessels

Having found a diagnosis of vasculitis, capillary toxic or hemorrhagic in a patient, the specialist will definitely prescribe treatment. Ascorutin is always present in the list of drugs, since its use allows you to strengthen the walls of blood vessels that wear out heavily with these ailments. In addition, "Ascorutin" takes care of increasing their stretching properties, reducing permeability. The dosage in such cases is determined by a specialist; it is not recommended to take the remedy on your own.

For cutaneous rosacea

The description of such a skin disease as rosacea suggests that capillary tissues begin to expand under it, due to which they become noticeable on the face. The first manifestations of the disease are small red stars, usually appearing on the cheeks, the tip of the nose. Sometimes they can occur on the forehead, chin. Then there are more such "stars", they turn into a real grid.

"Ascorutin" in this case helps along with other drugs prescribed by specialists. It is often recommended to use tablets for the preparation of decoctions, infusions, tonics, face masks. It is believed that the simultaneous use of the drug inside, outwardly, enhances its effectiveness. You can prepare a tonic with a complex in the following way:

  • brew an infusion of chamomile, cool;
  • add to the infusion two powdered Ascorutin dragees.

For varicose veins

Varicose veins are most often accompanied by the presence of bruises on the legs, spider veins. The medicine in such a situation is prescribed for prevention, but not treatment. Its reception relieves inflammation of the vascular wall, reduces its swelling, thereby preventing the formation of blood clots. However, this disease can be treated only under the supervision of a specialist, and therefore self-medication is strictly prohibited. How to drink Ascorutin tablets will be indicated by the doctor after the examination, the appointment of essential medicines.

During menstrual syndrome

During menstruation, the Ascorutin vitamin complex is recommended if they are plentiful and last a long time. The beginning of a new cycle is carefully calculated, after which the use of the vitamin begins a few days before it. Gynecologists "treat" similar conditions of women with "Ascorutin" usually for about ten days. And yet, you should not engage in self-assignment of the complex, since the cause of heavy menstruation may not be a lack of nutrients, but, for example, a hormonal imbalance. Then the indicated remedy will be ineffective, since it is necessary to undergo an examination, take pills of another pharmacological group.

When bleeding

These tablets are used for the following types of bleeding:

  • nasal;
  • uterine;
  • intestinal;
  • hemorrhoidal;
  • from gums and others.

However, do not forget that in such situations the complex is prescribed together with other drugs. It is not an option for emergency, immediate care. Its reception in the event of a sharp deterioration in a person's condition can cause irreparable harm.

Admission rules

Adults "Ascorutin" is recommended to drink up to three times a day. In childhood, the dosage remains the same, however, it is adjusted by the doctor prescribing the complex. The period of use of the funds is ten days. Before you start taking it, it is important to read the instructions, to clarify whether the expiration date has expired (shelf life of the drug is 3 years).

If the complex is used for the prevention of viral, influenza diseases, it is prescribed for children for up to ten days, half a tablet each. It is important to listen to the specialists who prescribe it, to prevent the development of an overdose state. It is best to drink dragees after meals, drink plenty of water. You should not dissolve, chew them, it is better to just swallow, as ascorbic acid negatively affects the condition of tooth enamel.

Side effects

Side effects as such when using the complex are usually not observed. However, its uncontrolled long-term use can cause a delay in menstruation, the formation of stones in the urinary system, kidneys. Before giving pills to children, you should make sure that they are not allergic to the components of the medicine.

If you drink more than ten pills at a time, an overdose occurs. It is accompanied by the following symptoms:

  • increased blood pressure;
  • the functioning of the renal system, pancreas is disrupted.
  • dyspeptic disorders;
  • sleep disorders.

Those who suffer from sudden drops in blood pressure have nothing to worry about - there were no cases that the complex lowered it. Therapy for an overdose of the drug involves the use of activated charcoal (at the rate of one tablet per ten kilograms of a person's weight), calling an ambulance.

Analogues

Foreign analogues of the complex are drugs such as:

  • "Detralex" - produced in France, most often used for varicose veins, hemorrhoids. The only contraindication to taking is an allergy to its components;
  • "Eskuzan" - produced in Germany, has several forms of release - ointment, tablets, solution. Not recommended in children under twelve years of age, during pregnancy, during lactation.

Domestic analogues of "Askorutin" are:

  • "Ascorutin D";
  • "Ascorutin-UBF";
  • "Prophylactin C";
  • Venarus, others.

Price

Askorutin does not belong to the category of expensive. The tool is available to anyone with even a small income. The cost of the complex varies from 25 to 46 rubles.

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