Ringer's solution for animals. How to administer Ringer's solution to a cat? Release form and composition of the Ringer-Locke solution

Cases of various kinds of intoxication in domestic and farm animals, unfortunately, are not uncommon. To alleviate the condition of patients in veterinary clinics in case of poisoning, drugs of a special variety are used - designed to restore the electrolyte background. One such drug is Ringer's solution. Instructions for using this particular tool, which has earned good reviews from consumers, will be discussed by us later in the article.

In veterinary medicine, this tool is used quite often. Such a solution can be used for cats, dogs, rabbits and other animals.

Release form and composition

This tool is supplied to veterinary clinics and pet stores in the form of a solution intended for injection. It is a colorless transparent liquid. Substances in the Ringer-Locke solution include the following:

• sodium bicarbonate;
• sodium chloride;
• potassium chloride;
• calcium chloride hexahydrate.

Distilled water is used as a solvent in the preparation of this solution. This medicine is supplied to the market in sealed sterile vials of 100 or 200 ml.

Features of the drug

This remedy is usually used in the same cases as isotonic sodium chloride solution (edible salt). However, at the same time, it is both more physiological and close to blood plasma. Including this feature of the drug explains the high degree of effectiveness of its action.

After injection, the Ringer-Locke solution is rapidly absorbed and distributed in animal tissues. At the same time, it does not have any irritating effect on the body of the animal. The positive effect provided by this drug is primarily due to the fact that it is able to quickly normalize the water-salt and acid-base balance.

Indications for use

According to the instructions, the Ringer-Locke solution can be administered to animals:

• with dysentery, vomiting, diarrhea and food poisoning;
• various kinds of thermal injuries - frostbite, burns;
• inflammation of the peritoneum;
• intestinal obstruction;
• bites of poisonous spiders or snakes;
• blood loss.

In addition, it is used for plasmapheresis.

Since Ringer's solution is compatible with many veterinary drugs, it is often used as a diluent in the treatment of other drugs. But the combination of drugs in this case should, of course, be selected exclusively by a specialist. Simultaneously with some drugs, this solution is not allowed to be used.

Methods of application and safety measures

Use Ringer's solution instruction prescribes only for intravenous infusion. Sometimes this medicine is also used as an external remedy. Thus, it is used, for example, for washing wounds and mucous membranes, if necessary.

In some cases, the Ringer for animals allows it to be administered intramuscularly. But injections of this medicine are made in this way, usually when treating only kittens, rabbits and puppies, and if the animal is really very ill. In small patients of veterinary clinics, finding thin veins is, unfortunately, often very difficult.

Ringer's solution does not belong to the class of harmful and hazardous substances. However, when using it, of course, one should adhere to the standard technology for the use of veterinary drugs. Injections of this medicine, for example, must be done with medical gloves.

Instructions for use of the Riegner-Locke solution: dosage of the drug

It is impossible to prescribe this medicine to an animal on its own. They are treated only after visiting the clinic on the recommendation of a veterinarian. Usually only specialists inject this medicine into animals. In this case, the veterinarian chooses the dosage of Ringer's solution depending on the specific disease and the weight of the animal.

For adult cats, for example, the drug is usually used in an amount of 100-150 ml per day. In this case, its single dose is 50 ml.

Contraindications for use

The Ringer-Locke solution helps animals with intoxication very well. But unfortunately, it is not possible to use this remedy for the treatment of cats, rabbits, horses, dogs, etc. in all cases. According to the instructions for use of the Ringer-Locke solution, it should not be administered if the animal has, for example, problems such as:

• swelling of tissues or brain;
• heart failure;
• anuria;
• oliguria;
• severe kidney damage.

With edema, this drug can aggravate the situation of the animal. The use of the drug in this case often even leads to death. Among other things, when using this remedy in the body of cats, dogs, etc., blood flow is accelerated. In heart failure, the drug can thus actually be very harmful. In this case, the heart with increased blood flow may simply not be able to cope. And this, in turn, unfortunately, can lead to the death of a pet.

With caution, according to the instructions, the Ringer-Locke solution should be used for acidosis, hypovolemia and other similar diseases.

Side effects

Ringer's solution belongs to the group of safe drugs. No side effects are usually observed in the treatment of them in animals. Only sometimes pets may experience allergic reactions to this medicine. In this case, the drug, of course, should be stopped.

Of course, when using this tool, you must strictly observe the dosage. If too much medicine is given to the animal, it may experience chloride acidosis and overhydration. With the development of such conditions in an animal, the dose of the drug taken by him should be reduced or the solution should be completely canceled.

Drug analogues

The instructions for using Ringer's solution are described above. In veterinary medicine, this medicine is used very often. And this remedy helps animals with intoxication very well. At the same time, Ringer's solution is inexpensive. The price of a bottle of the drug in veterinary pharmacies is usually no more than 50-60 rubles. But of course, if necessary, this drug can be replaced with some of its analogues.

For example, the drugs differ in the same therapeutic effect as the Ringer-Locke solution:

• "Regidron", produced in the form of a powder and intended for oral use. This medicine is usually used in animals dehydrated due to diarrhoea.
• This remedy is used in approximately the same cases and in the same dosages as the Ringer-Locke solution.

In this article, you can read the instructions for using the drug Ringer Locke. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Ringer's solution in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Ringer's Locke solution in the presence of available structural analogues. Use for the treatment of alkalosis and correction of water and electrolyte balance in adults, children, as well as during pregnancy and lactation. The composition of the drug.

Ringer's solution- a rehydrating agent, has a detoxifying effect, stabilizes the water and electrolyte composition of the blood. When used as a means of replenishing the volume of circulating blood, due to the rapid exit from the bloodstream into the extravasal space, the effect persists for only 30-40 minutes (and therefore the solution is only suitable for short-term replenishment of the volume of circulating blood).

Compound

Sodium chloride + Calcium chloride + Potassium chloride + excipients.

Indications

• as a plasma-substituting agent in the absence of the need to replace red blood cells, incl. with shock, collapse, burns, frostbite, prolonged vomiting, diarrhea;
• for the correction of water and electrolyte balance in acute diffuse peritonitis and intestinal obstruction, intestinal fistula;
• dehydration of various etiologies;
• metabolic alkalosis, accompanied by fluid loss.

Release form

Solution for infusion in a polymer container or infusion bag 100 ml, 200 ml, 250 ml, 400 ml, 500 ml and 1000 ml.

Instructions for use and method of use

Intravenous drip at a rate of 60-80 drops / min or jet.

The daily dose for adults - 5-20 ml / kg, if necessary, can be increased to 30-50 ml / kg.

The daily dose for children is 5-10 ml / kg, the rate of administration is 30-60 drops / min, with shock dehydration, 20-30 ml / kg is initially administered.

The course of treatment is 3-5 days.

Side effect

• hyperhydration;
• hypokalemia;
• allergic reactions.

Contraindications

• hypernatremia;
• hyperchloremia;
• acidosis;
• chronic heart failure;
• pulmonary edema;
• swelling of the brain;
• chronic renal failure;
• hypervolemia;
• concomitant therapy with glucocorticosteroids;
• hypersensitivity to the components of the drug.

Use during pregnancy and lactation

During pregnancy, it is used in cases where the expected benefit to the mother outweighs the possible risk to the fetus.

You should refrain from breastfeeding during the period of use of the drug due to the lack of relevant clinical data.

special instructions

With prolonged use, it is necessary to control the concentration of electrolytes in plasma and daily diuresis.

In the case of rapid administration of a large volume, it is necessary to control the acid-base state and the level of electrolytes. A change in blood pH (acidification) leads to a redistribution of potassium ions (a decrease in pH leads to an increase in the content of potassium ions in the blood serum).

Only undamaged vials with a clear solution can be used.

drug interaction

It is possible to increase sodium retention in the body while taking the following drugs: NSAIDs,

androgens, anabolic hormones, estrogens, corticotropin, mineralocorticoids, vasodilators or ganglion blockers.

When taken with potassium-sparing diuretics, ACE inhibitors and potassium preparations, the risk of developing hyperkalemia increases.

In combination with cardiac glycosides, the likelihood of their toxic effects increases.

Analogues of the drug Ringer Locke

Ringer's solution has no structural analogues for the active substance.

Analogues for the pharmacological group (regulators of water and electrolyte balance in combinations):

• Acesol;
• Disol;
• Ionosteril;
• Quintasol;
• Methusol;
• Sodium fumarate is complex;
• Neohemodes;
• Plasma-Lit 148 aqueous solution;
• Plasma-Lit 148 with 5% Glucose;
• Hartmann's solution;
• Regidron;
• Ringer lactate;
• Ringer Lactate Viaflo;
• Ringer's acetate;
• Ringer's lactate with magnesium;
• Bieffe complex sodium lactate solution (Ringer's lactate solution);
• Sorbilact;
• Compound sodium lactate;
• Trisol;
• Chlosol.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.

Instructions for use of the Ringer-Locke solution for the treatment of animals
with dehydration and intoxication of the body, blood loss, as well as for washing eyes and wounds
(organization-developer: CJSC Mosagrogen, Moscow)

I. General information
Trade name of the medicinal product: Ringer-Locke solution (Solutio Ringer-Locke).
International non-proprietary name: Ringer-Locke solution.

Dosage form: solution for injections.
Ringer-Locke solution in 1 ml contains sodium chloride - 8 mg as active ingredients, potassium chloride - 0.2 mg, calcium chloride - 0.2 mg, sodium bicarbonate - 0.2 mg, glucose - 1 mg, and as solvent - water for injection.
In appearance, the drug is a clear, colorless liquid.

The Ringer-Locke solution is produced in glass bottles of the appropriate capacity, sealed with rubber stoppers, reinforced with aluminum caps.
Store the medicinal product in the manufacturer's closed packaging in a dry place, protected from direct sunlight, separately from food and feed, at a temperature of 0°C to 25°C.
The shelf life of the medicinal product, subject to storage conditions, is 2 years from the date of manufacture.
It is forbidden to use the drug after the expiration date. It should be kept out of the reach of children.
The unused medicinal product is disposed of in accordance with the requirements of the legislation.

II. Pharmacological properties
Ringer-Locke's solution refers to drugs that affect the water and electrolyte balance in the body. The drug is used as a rehydrating agent, to stabilize the water and electrolyte composition of the blood, and has a detoxifying effect.

According to the degree of impact on the body, the Ringer-Locke solution belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76).

III. Application procedure
Ringer-Locke solution is used in animals for dyspepsia and other diseases accompanied by dehydration and intoxication of the body, blood loss, as well as for washing wounds and eyes.

A contraindication for the use of the drug is the individual hypersensitivity of the animal. With a pronounced violation of the excretory function of the kidneys, intravenous administration of the Ringer-Locke solution is contraindicated.

Ringer-Locke solution is used subcutaneously or intravenously in the following doses:

Doses and terms of application depend on the weight of the animal and the course of the disease. With subcutaneous injections, the dose of the drug is administered fractionally in different places.

Symptoms of overdose in animals have not been identified.
Features of the action of the drug during its first use and when it is canceled have not been established.

The use of the drug in large quantities can lead to the development of chloride acidosis, hyperhydration. With such complications, reduce the dose or cancel the drug.

The use of Ringer-Locke's solution does not exclude the use of other drugs.

Animal products during and after the application of the Ringer-Locke solution are used without restrictions.

IV. Measures of personal prevention
When working with the Ringer-Locke solution, you should follow the general rules of personal hygiene and safety precautions provided for when working with drugs. At the end of work, hands should be washed with warm water and soap.
In case of accidental contact of the drug with the skin or mucous membranes of the eye, they must be washed with plenty of water.
Empty drug bottles must not be used for domestic purposes, they must be disposed of with household waste.

Organization-manufacturer: CJSC "Mosagrogen"; 117545, Moscow, 1st Dorozhny proezd, 1.

It is produced in the form of an injection solution, the active ingredients of which are sodium chloride (0.8 grams), potassium (0.02 grams), calcium (0.02 grams), sodium bicarbonate (0.1 grams) and glucose.

As a solvent, there is also one hundred milliliters of water for injection. The drug is sterile and externally is a clear, colorless liquid. The product is packaged in glass bottles with a capacity of ten, twenty and one hundred milliliters. The vials are hermetically sealed with rubber stoppers protected by rolled aluminum caps. Each container must be labeled, which must indicate the name of the drug, manufacturer, volume in milliliters, expiration date, serial number, method of use, storage conditions, the inscriptions "Sterile", "For animals". Instructions for use must also be included.

Properties

Ringer-Locke solution designed to regulate the acid-base and water-salt balance in the body of various animals. From the point of injection, the agent, after administration, is quickly absorbed and spreads through the tissues and organs of the animal, without irritating them.

Application and doses

R-or Ringer-Locke is used intravenously or subcutaneously. For subcutaneous injections, the principle of fractional injection at different sites should be used.

The dose for cattle and horses ranges from one thousand to three thousand milliliters. For calves up to a year - 200-400 milliliters, and for small cattle the dose is ten times less than for large cattle - 100-300 milliliters. The smallest dose for piglets and lambs is 25-100 milliliters. The exact doses and terms of application are determined by the characteristics of the course of the disease and the weight of the animal. The solution should be prepared immediately before use, taking into account the requirements for the preparation of such liquids. The application is the same as for the isotonic solution of NaCl.

Side effects

Complications and side effects when using the drug in recommended doses were practically not observed. However, if the Ringer-Locke solution is used in increased volumes, overhydration and chloride acidosis may well develop. If the development of such complications is noticed, the dose should be reduced or the drug should be completely discontinued. In the treatment of Ringer-Locke solution, the use of other drugs is allowed.

Contraindications

It is not allowed to administer the Ringer-Locke solution intravenously in case of a clear violation of the excretory activity of the kidneys.

Both during and after treatment with the Ringer-Locke solution, animal products can be used without restrictions. Working with this solution requires compliance with the general safety, sanitation and personal hygiene rules that are prescribed for working with medicinal products for animals.

Storage

The drug should be stored in the container and packaging of the manufacturer, closed, protected from direct sunlight, dry and inaccessible to animals and children, away from feed and food. The storage temperature range is from zero to twenty-five degrees. The shelf life of the Ringer-Locke solution is two years from the date of its release, after this period the product is considered unusable and must be disposed of in the prescribed manner.

pharmachologic effect

The “physiological” composition of the Ringer-Locke solution is closer to the composition of the plasma than the isotonic solution of NaCl.

Indications for use

The remedy is used against the development of dehydration and intoxication of the body with food poisoning, and other diseases, including El Tor cholera. It is prescribed for circulatory disorders, burns, in which dehydration is manifested, for shock, both surgical and postoperative, and provoked by blood loss, diarrhea (diarrhea), inflammation of the peritoneum.

I. GENERAL INFORMATION

1. Ringer-Locke solution (Solutio Ringer-Locke).

2. Ringer-Locke solution - a drug in the form of a solution for injection containing sodium chloride, potassium chloride, calcium chloride, sodium bicarbonate, glucose as active ingredients and water for injection as a solvent.

3. The drug is a colorless transparent sterile liquid.

4. The Ringer-Locke solution is released packaged in 100 and 200 ml in sterile hermetically sealed glass vials, sealed with rubber stoppers and rolled in with aluminum caps.
Each packaging unit is labeled with the manufacturer, its address and trademark, the name of the medicinal product, the name and content of active substances, the method of application, the batch number, the date of manufacture, the expiration date, the amount of the drug in the vial, storage conditions, the inscriptions "Sterile" , "For animals", TU designations and are accompanied by instructions for use.
Store in a dry place at a temperature from 0 to 25 0С.
The shelf life of the Ringer-Locke solution, subject to storage conditions, is 2 years from the date of manufacture. It is forbidden to use the medicinal product after its expiration date.

II. PHARMACOLOGICAL PROPERTIES

5. Ringer-Locke solution is isotonic to animal blood plasma, regulates water-salt and acid-base balance in animals.

6. After administration, the drug is rapidly absorbed from the injection site and distributed in the organs and tissues of the animal.

According to the degree of impact on the body, the Ringer-Locke solution according to GOST 12.1.007 refers to low-hazard substances (hazard class 4), does not irritate tissues.

III. HOW TO USE

7. Ringer-Locke solution is used for animals with dyspepsia and other diseases accompanied by dehydration and intoxication of the body, blood loss, for washing wounds and eyes.

8. Ringer-Locke solution is used subcutaneously or intravenously in the following doses (in ml per animal):

10. The use of Ringer-Locke solution does not exclude the use of other drugs.

11. There are no contraindications to the use of the Ringer-Locke solution.

12. Animal products during and after the application of the Ringer-Locke solution are used without restrictions.