Gel Metrogyl denta - instructions for use. Metrogyl denta gel: step-by-step instructions for use, indications, review of analogues and reviews

1 gram of gel contains: Active substances: Metronidazole benzoate 16.0 mg (equivalent to metronidazole 10.0 mg) Chlorhexidine digluconate 20% solution 2.5 mg (equivalent to chlorhexidine digluconate 0.5 mg)

We often do not pay attention to gum problems, naively believing that their inflammation is not a serious disease and everything can be cured on our own. How to be? After all, although on your own, you will have to treat the gums. In the article we will talk about the dental drug Metrogyl Denta, which has long confirmed its effectiveness in the treatment of gums.

Metrogyl Dent is produced in the form of a gel. It is soft in texture. The color is white or, one might say, close to white. Its release form is different and differs in weight. Produced in plastic tubes weighing 5 g, 10 g and 20 g.

The drug is produced by a large company, Unique Pharmaceutical, which has its offices in almost all countries. The release of all products is controlled by GMP rules. Their requirements are based on the implementation of quality control of their products at all levels of its manufacture.

When buying Metrogyl Dent at a pharmacy, pharmacists will not require a prescription from a doctor. Store at an air temperature of less than 25°C and no more than three years.

Compound

• Metronidazole benzoate. This is a special antibacterial component. It has the ability to quickly penetrate into saliva, thereby creating a sufficiently high bactericidal effect in the oral cavity. One gram of gel contains 16 mg of metronidazole benzoate.
• Bigluconate chlorhexidine (20% solution). This is a special antiseptic component. It helps fight various types of protozoa, bacteria and herpes viruses. In addition, he shows his activity against purulent secretions. One gram of Metrogyl Dent gel contains 2.5 mg of chlorhexidine bigluconate.
• Excipients. These substances include: water, carbomer-940, sodium hydroxide, levomenthol, propylene glycol.

Indications

• Cheilite.
• Treatment of gingivitis in chronic and acute form.
• Aphthous stomatitis.
• Juvenile periodontitis.
• Inflammation of the mucosa when wearing prostheses.
• Periodontitis.
• Inflammation of the hood over the wisdom tooth.
• Ulcerative necrotic or Vincent's gingivitis.
• Periodontitis (acute and chronic).
• Post-extraction alveolitis.
• Periodontal disease, which was formed after complicated gingivitis.
• Periodontal abscess (combined treatment).
• Alveolitis of the socket after tooth extraction.

Advantages and disadvantages

Metrogil Dent is especially valuable because it is generally the first dental gel that appeared in our country. It can be purchased at any pharmacy. The gel has its pros and cons.

Advantages:

• Good fixation on the mucosa.
• Affordable price.
• It has good antimicrobial activity.

Flaws:

• Does not give an analgesic effect.
• Medicinal components are contained in very small doses. That is why the use of the drug is not controlled, and it is freely dispensed without a prescription. It is impossible to do harm with this tool. And that is why it is less effective.

The main components of the gel do not fight inflammation. Metrogyl Denta acts only on pathogenic bacteria, but cannot block inflammation in the tissue. Therefore, in the treatment of gums, it is best to give preference to drugs of combined action.

Application

Peculiarities

The gel should be applied to the gums only after a thorough cleaning of the oral cavity. Before applying it directly, it is necessary to thoroughly dry the mucous membrane with a dry gauze swab. This will ensure the best fixation of the gel on the mucosa.

Apply the gel twice a day. It is advisable to do this in the mornings and evenings. The procedure is best performed standing in front of a mirror. First you need to squeeze the gel from the tube onto your finger or cotton swab. Then apply it to the marginal part (which is adjacent directly to the teeth). Also pay special attention to the area on the side of the tongue. Do not eat for three hours, and drink for 30 minutes. If after the treatment itself saliva accumulates, it is advisable to spit it out, and not save it. The use of the gel should not last more than 10 days.

You can not completely ignore brushing your teeth during treatment with Metrogyl. Also, the drug is not a substitute for the cleaning itself. During application, do not allow the product to get into the eyes.

In order for the drug to give the maximum effect, you should not drink alcohol during treatment.

How to treat specific diseases

If inflammation of the gums is observed in children after 6 years and in adults, then it is necessary to apply the gel with a cotton swab or finger. After that, try not to eat or drink, so as not to wash off the gel. Course: 7-10 days.

What to do if you suffer from periodontitis? Gel processed periodontal pockets. In addition, the patient carries out the application with the help of a gel after dental deposits have been removed. For the very first time, the procedure can be performed by a dentist, then it will be done by the patient himself. The course is also 7-10 days. In chronic periodontitis, the course of treatment is repeated 2-3 times a year.

In order to avoid post-extraction alveolitis, it is advisable to start processing the hole immediately after tooth extraction. Course: no more than 10 days.

Treatment of gingivitis

This disease must be treated only comprehensively. One gel will not help here. Inflammation of the gums usually occurs as a result of plaque and deposits. Therefore, the use of the gel will be effective only after cleaning the dental deposits, which the dentist can do.

After the procedure, the doctor usually prescribes drug therapy. Usually, such therapy includes antiseptic rinses and applications using Metrogyl gel. If the patient has a severe form of inflammation, the dentist may prescribe antibiotic therapy.

If you treat with a gel without removing plaque and stone, then at the very beginning you can notice some effect of improving the condition. Usually this is a decrease in edema and a decrease in bleeding. But this phenomenon will only be temporary while you use the drug. Further, the inflammatory process proceeds without any particular symptoms, but the destruction of bone tissue will continue inside. As a result, after some time, the teeth will become mobile.

With gingivitis, Metrogyl is also applied to the gums twice a day. Be sure to brush your teeth before use. Then rinse your mouth thoroughly with an antiseptic solution (for example, Chlorhexidine) for one minute. The last step is to dry the wet gums with a gauze swab.

Treatment of stomatitis

Metrogil is not effective in the treatment of this disease. And this is understandable, since its active components do not prevent the activity of viruses at all. The drug can give a small effect in aphthous form of stomatitis. And then only in those forms in which the disease is caused by pathogenic bacteria.

Metrogyl Denta during pregnancy

The gel contains an antibiotic. This ingredient is metronidazole. According to FDA recommendations, it can be used during pregnancy and lactation.

But the manufacturer Unik Pharmaceutical himself strictly prescribed in his instructions that the drug should not be used by women in the 1st trimester. Also, it is generally not recommended for women at the stage of feeding.

Other applications

As the reviews show, Metrogil also allows you to cope with the following problems:

• Seborrhea.
• Acne.
• Trophic ulcer (only in complex treatment).
• Eczema.
• Bedsores.
• Hard-to-heal wounds.

For the treatment of the described diseases, it is necessary to apply the gel to the affected area twice a day. The course here differs in duration from gum treatment. It ranges from three to ten weeks. The time of treatment depends on the severity of the lesion.

Contraindications

Gel for gums Metrogyl is contraindicated:

• In children up to 6 years of age.
• If there is an individual intolerance to metronidazole or chlorhexidine, as well as other auxiliary components of Metrogyl Denta.

Side effects

Rare, but may occur:

• Allergy in the form of hives, skin rash or itching.
• Headache.

drug overdose

If the gel is swallowed in large quantities, side effects are greatly enhanced. Metronidazole has this effect. The patient begins severe nausea, dizziness or vomiting. With a severe overdose, convulsions and paresthesia may begin. In these cases, the patient is usually shown gastric lavage and appropriate symptomatic therapy.

Reviews

I am familiar with Metrogil Denta. I use it regularly to prevent gum disease. I get stones very often. Therefore, in the past, I always had to attend ultrasonic cleaning. The procedure is unpleasant. To avoid it, I began to smear the gums with these agents. While it helps a lot, I have been cleaning for a long time. I also really like the pleasant menthol flavor in the gel, which freshens the breath.

Advice on the use of Metrogil was given to me by a familiar dentist. I think a good specialist will not advise bad. Everyone told me that Metrogil Denta is expensive. I do not think so. Two hundred rubles is not money. It is very economically consumed, with rational use. I treat my bleeding gums with it. If I suddenly burn my tongue or feel a wound in my mouth, then I apply the gel.

Metrogyl Denta is a drug that is best used for prevention, with minor problems in the oral cavity and as part of complex therapy.

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Hello dear readers. The topic of our today's article is Metrogil Dent gel. A very popular dental remedy, actively advertised and prescribed by doctors. We will analyze several questions at once - what it is, what it consists of, what it helps with, what side effects and contraindications it has. After all, there are many medicines that doctors prescribe, in general, thoughtlessly. Not everything is useful and safe, which experts recommend to us.

What is Metrogil Denta?

So, as the instructions say, we have a gum gel designed to prevent and treat various inflammatory manifestations. But this is only part of the evidence. This medicine combines an antibiotic and an antiseptic, has a wide spectrum of action. Available in tubes of 20 grams. The gel is sold through most pharmacy chains. Its acquisition does not require a prescription.

When squeezed out, you will see that the substance inside the tube is transparent, almost colorless. It tastes and smells like baby toothpaste.

Metrogyl Denta - gel for gums

The composition of the drug

The gel contains metronidazole (10 mg/1 g of gel) and chlorhexidine digluconate (0.5 mg/1 g). Additional substances are also used - water, carbomer, propylene glycol, levomenthol and others. Chlorhexidine digluconate is the most popular antiseptic in dental practice, metronidazole is one of the most important medicines used in the fight against bacteria.

It is created as a synthetic analogue of azomycin (produced by bacteria streptomycetes).

Video - Official instructions for use

Preparations - analogues

In the CIS, several drugs of similar action are produced. One of them is a periodontal drug called "". Its composition is the same - metronidazole and chlorhexidine, but the volume of the tube is only 10 grams. Other analogues may also contain chlorhexidine and other substances that destroy streptococci, staphylococci, etc.

Gel for gums ASEPTA with propolis

5 analogues of the drug Metrogyl Denta:

Name	Description	Price
Metronidazole Denta Gel	Antibacterial drug for the treatment of inflammatory and infectious processes in the oral cavity	123 rubles
Dentamet gel	Combined antimicrobial drug. The effectiveness of the drug lies in its composition of active ingredients: metronidazole and chlorhexidine	100 rubles
Metrodent	Antimicrobial and antiseptic agent for topical use in dental practice	153 rubles
Metronidazole denta gel	An effective and inexpensive remedy that will relieve inflammation of the gums and other troubles on the oral mucosa	239 rubles
Metroviol Denta gel	The effectiveness of the drug is due to the presence of two antibacterial components - metronidazole and chlorhexidine	55 rubles

Indications for use

Metrogyl Denta is a fairly versatile and multifunctional local remedy. It is effective for eliminating the negative effects of diseases such as:

• stomatitis. Here it should be clarified that only the aphthous form. Since it is ineffective with herpetic;
• periodontitis. As part of the complex therapy of the disease;
• cheilitis;
• inflammation of the gums under the prosthesis;
• periodontal abscess. As part of complex therapy.

Use in alveolitis

Alveolitis is a common disease that occurs in many patients after tooth extraction. This is suppuration in the socket of the tooth, caused either by the washing out of the blood clot, or by its improper formation / damage.

To eliminate the consequences, the hole is cleaned. Then the gel is put into it. After that, the patient is told how to perform this procedure on their own. The course of treatment is from 1 to 1.5 weeks, two procedures per day. According to statistics, the gel shows good results in the fight against recurrence of infections in the sockets of extracted teeth.

Use in periodontitis

In order for the gel to be effective, you must first remove hard and soft dental deposits. After that, the doctor lays a small amount of Metrogyl Dent directly into the periodontal pockets. Such applications are installed for half an hour twice a day with a course of up to one and a half weeks.

The number of necessary procedures is individual and depends on the condition in which the patient was admitted.

Use in various forms of gingivitis

Gingivitis, including juvenile gingivitis, is one of the most common diseases affecting the population. It is caused by the multiplication of pathogenic bacteria, poor oral hygiene. Therefore, in many cases, a gel containing antibacterial components is quite effective in eliminating the problem. However, as in the case of periodontitis, plaque must first be removed and. Without this, the procedure becomes a waste of time and money.

The gel is applied in a thin layer on the marginal gum. It is recommended to do the application for 20-30 minutes twice a day. It is important that the substance is not washed off by anything. That is, you can’t drink water, tea, etc. at this time.

Treatment of aphthous stomatitis

How effective is Metrogyl Denta gel for stomatitis? It all depends on what form of the disease you are dealing with. As you know, there are three main forms - catarrhal and ulcerative. There is sense from the gel only with aphthous. Lubricate the lesions with it twice a day. The duration of treatment can be up to 10 days. It is worth lubricating not only the aphthae themselves, but also the surrounding area. So you will ensure greater antibacterial effectiveness. Ideally, the procedure is carried out after rinsing the mouth with an antiseptic.

Painful wisdom tooth eruption accompanied by inflammation

Often, dentists prescribe Metrogyl Denta to patients who have a wisdom tooth that erupts for a long time. Let's try to figure out whether the drug can improve the condition. Problems with the eruption of the last molars are known to everyone. The tooth comes out for a long time, traumatically, causing inflammation and redness of the gums, pain. The gel is effective only for eliminating external processes. That is, it cannot penetrate into the thickness of tissues, stop inflammation, improve conditions for eruption, etc.

Often there is a disease such as inflammation of the hood from the tissues of the gums hanging over the tooth. In this case, the antibacterial effect of Metrogil will be more noticeable.

Some patients try to use dental gel for acne, believing that the presence of an antibiotic and antiseptic in the composition should help them.

We will have to disappoint such experimenters, and here is why.

1. Both components that make up the composition are unable to fight those types of bacteria that lead to acne. This is, first of all, P.acnes and epidermal staphylococcus aureus.
2. Even if the drug were effective in eliminating these two types of microorganisms, the concentration of metronidazole in it is minimal.
3. The main bacterial activity occurs in the deep layers of the skin, including the follicles. Metrogyl Denta is a surface preparation.

Therefore, it can only partially eliminate bacteria on the upper layer of the skin, but is useless in the fight against infectious and inflammatory skin diseases. Therefore, there is no point in trying to smear the face with a dental preparation. For these purposes, there are specialized creams based on antibiotics. Their composition is designed to combat the above types of microorganisms.

Metrogil Dent with angulitis (jamming in the corners of the mouth)

Often in children and adults, a wound, erosion, a crack in the corner of the mouth is found. They are usually painful and unpleasant, often covered with a white or gray coating. Seizures themselves appear as a result of trauma, various internal diseases. An infection quickly enters the open wound, causing a local inflammatory process and redness of the area. Given the superficial and open nature of such lesions, the use of Metrogyl Dent gel is quite justified and effective enough to eliminate the infection.

However, it should be borne in mind that the bacteria that enter the wound are different. Sometimes these are microbes against which Metronidazole is useless. In this case, the use of specialized targeted antimicrobial drugs is recommended.

Advantages, disadvantages, features of the gel Metrogyl Denta

Another advantage is the cost factor. But when it comes to medicine, efficiency is more important. The second point - unlike ointments, the gel is well fixed on the mucous membranes of the gums, cheeks, palate. There is also an average level of activity in the fight against pathogenic microorganisms.

And now a fly in the ointment. Many patients suffering from gum disease would like the drug to have a pronounced analgesic and anti-inflammatory effect.

But you will not achieve either one or the other using Metrogil Dent. The second point that should be voiced concerns dosages. They are less than required for the actual treatment of infectious diseases that the gel is designed to fight. What is it for? In order to be able to sell the medicine in bulk and without prescriptions from doctors. There is only one plus from this - it is difficult to harm yourself. This was done taking into account the fact that patients tend to take various kinds of drugs uncontrollably. In total, we have two antimicrobials in small dosages, barely sufficient for an antibacterial effect. They are unable to block the inflammatory process in general. Therefore, do not be surprised if the gel does not help you with exacerbation of periodontitis.

Experts believe that a combination of Chlorhexidine (in the form of rinses) and Holisal gel applications would be more effective. The difference in efficiency is huge. But the price of Holisal is almost 2 times higher. Add to it the cost of Chlorhexidine solution and understand why people buy Metrogyl Denta.

Clinical studies and real experience of application have shown that when applied topically, the substance is practically not absorbed. That is, it has only a superficial effect. This is one of the reasons why it may not have an anti-inflammatory effect.

On the other hand, at least it stays on the gums better than any gum ointment sold at the pharmacy.

Application of the gel according to the instructions

Many buyers are interested in how to apply the gel correctly. According to the instructions, you first need to carefully remove plaque from the surface of the teeth. After that, the mucous membranes are blotted with gauze. This is necessary so that the gel is fixed on the surface as reliably as possible. It is recommended to use the drug after breakfast and after dinner. That is, first you eat, then brush your teeth, remove excess moisture, and then use the gel. The recommended duration of treatment is from 5-7 to 10 days.

Doctors are convinced that Metrogil Denta should be used in combination with other methods of treatment. In particular, it is recommended to consult a hygienist first. He will do a professional cleaning. Additional rinsing with antiseptics may also be prescribed. In case of serious diseases caused by the mass reproduction of bacteria, doctors prescribe additional treatment

But what if you apply the gel without taking into account these recommendations? In most cases, you will get a temporary effect. Part of the external manifestations will be eliminated. But inside the gums, the inflammatory process will continue. Moreover, it can reach other tissues, including those that hold the tooth in the socket.

Before using the gel, it is best not only to brush your teeth, but also to additionally rinse your mouth with a solution of Chlorhexidine. After that, dry your teeth and gums, squeeze a little of the substance onto your finger and gently apply to the area of ​​\u200b\u200bthe gum where it covers the surface of the teeth. You need to lubricate the gums both from the outside and from the inside.

After that, you need to refrain from water and other liquids for half an hour and from food for 2 hours. Do not be afraid that part of the substance will enter the esophagus with saliva. You don't need to spit. The drug will not harm your stomach and will not wash off completely. Before going to bed, repeat the procedure, remembering to brush your teeth and rinse your mouth first.

Use during pregnancy and while breastfeeding

How to treat diseases of the oral cavity and at the same time not harm the unborn child? What do the instructions say? On the one hand, the FDA considers Metronidazole to be safe for pregnant and lactating women. On the other hand, the manufacturer himself indicates that in the first trimester of pregnancy and during breastfeeding, it is better to stop using the drug. The only alternative for lactation is to temporarily transfer the child to artificial nutrition.

Returning to questions about analogues, we recall again. A drug based on choline salicylate is approved for use during pregnancy, but under the supervision of an obstetrician-gynecologist. If you believe the experts, then you can use this gel even in the early stages and during the feeding of the child.

Contraindications, side effects, precautions

Parents are interested in whether children can use Metrogyl Denta. According to the instructions, the gel is approved for use in patients older than 6 years. The question of safety for pregnant and lactating mothers is also often raised. The drug is generally harmless and is contraindicated only in the first months of pregnancy and for children under six years of age. However, do not forget that individual patients may have individual allergic reactions to both components. They can manifest as skin rashes, itching. Some people may experience nausea and other gastrointestinal symptoms. If you experience any of these symptoms, stop using the gel and contact your doctor. Other contraindications are not indicated.

In terms of the use of the gel for children, it is more relevant to raise the question not of safety, but of the effectiveness of the drug. For in many cases it is doubtful. With significant inflammation, it is useless. That is, it is better to use analogues made on the basis of other components or with different dosages.

What happens if you swallow a lot of gel? Still, our children are big fans of experiments on their bodies and can swallow not only toothpaste. Chlorhexidine is almost not absorbed, but metronidazole causes a number of side effects. First, from the gastrointestinal tract. These are nausea, vomiting, discomfort in the stomach and intestines. Feeling weak, dizzy. Seizures and other unpleasant symptoms are possible. If you find that the child has swallowed the gel, call an ambulance. Gastric lavage is usually done, and then the consequences are treated.

As for the interaction of the gel with other drugs, the manufacturer and other sources do not indicate this information.

Release forms, storage

Dental gel Metrogyl Denta is available in plastic or aluminum tubes. The neck is always sealed with foil. The tube is screwed on with a plastic cap with a sharp protrusion to open the membrane. The sealed tube, together with instructions for use, is placed in a cardboard box. The modern pharmaceutical industry produces packages of 5, 10 and 20 g.

It is necessary to store the tube at a temperature not higher than +25 degrees, away from powerful light sources, heating devices. Keep away from children. Shelf life - no more than 3 years from the date of issue. See the date of manufacture on the packaging.

Metrogil Denta - storage

In this article, you can read the instructions for using the drug Metrogil. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Metrogil in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Metrogil in the presence of existing structural analogues. Use for the treatment of gingivitis, stomatitis, vaginosis and other infectious diseases in adults, children, as well as during pregnancy and lactation.

Metrogil- broad-spectrum antiprotozoal and antibacterial agent. The mechanism of action of the drug is to restore the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microorganism cells, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria. The active substance of the drug is Metronidazole.

Pharmacokinetics

After ingestion of a single dose of the drug 200 mg or 400 mg Metrogyl is rapidly and completely absorbed. It has a high penetrating ability into tissues (lungs, kidneys, liver, skin), cerebrospinal fluid, brain, bile, saliva, amniotic fluid, vaginal secretion, seminal fluid, breast milk. Excreted by the kidneys (60-80% of the dose), 20% of the drug is excreted unchanged.

Indications

• protozoal infections (amebiasis, trichomoniasis, giardiasis, balantidiasis, trichomonas vaginitis and urethritis, amoebic dysentery);
• anaerobic infections (caused by Bac.fragilis and other bacteroids, fusobacteria, eubacteria, clostridia, anaerobic cocci);
• after surgical interventions on the organs of the abdominal cavity and urinary tract (intraperitoneal infections, appendicitis, cholecystitis, peritonitis, liver abscess, postoperative wound infections, postpartum sepsis, pelvic abscesses, peritonitis; including prevention of postoperative anaerobic infections);
• respiratory tract infections (necrotic pneumonia, lung abscess);
• septicemia;
• gas gangrene;
• osteomyelitis;
• tetanus;
• meningitis, brain abscess
• rosacea (pimples) (including post-steroid);
• vulgar acne;
• oily seborrhea, seborrheic dermatitis;
• trophic ulcers of the lower extremities (against the background of varicose veins, diabetes mellitus);
• poorly healing wounds;
• bedsores;
• hemorrhoids, anal fissures
• bacterial vaginosis of various etiologies, confirmed by clinical and microbiological data;
• candidal vulvitis and vulvovaginitis;
• acute and chronic gingivitis;
• acute ulcerative necrotic gingivitis of Vincent;
• acute and chronic periodontitis;
• juvenile periodontitis;
• periodontal disease complicated by gingivitis;
• aphthous stomatitis;
• cheilitis;
• inflammation of the oral mucosa when wearing prostheses;
• post-extraction alveolitis;
• periodontitis, periodontal abscess (as part of combination therapy).

Release forms

Film-coated tablets 200 mg and 400 mg.

Gel for vaginal use Metrogyl Plus 1%.

Gel for external use 1%.

Solution for intravenous administration (injections in ampoules for injection) 5 mg/ml.

Suspension for oral administration.

Dental gel Metrogyl Denta.

Instructions for use and method of use

Tablets

Inside during meals or after meals, without chewing or drinking milk.

Adults and children over 15 years old - 200-400 mg 2-3 times a day.

The dose of the drug and the course of treatment is determined by the nature of the infection.

Trichomoniasis: 200 mg 3 times a day for 7 days; women need to additionally prescribe metronidazole in the form of vaginal suppositories or vaginal ointments. If necessary, you can repeat the course of treatment or increase the dose to 750-1000 mg per day. Between courses, you should take a break of 3-4 weeks with repeated control laboratory tests. An alternative therapy regimen is the appointment of 2 g once to the patient and his sexual partner.

Amoebiasis: adults - 400 mg 3 times a day; children - 30-40 mg / kg per day in 3 divided doses. The course of treatment is 7-10 days.

Amoebic liver abscess: adults - 400 mg or 800 mg 3 times a day in combination with antibiotics (tetracycline or other methods); children - 30-35 mg / kg per day (in 3 divided doses). The course of treatment is 5-10 days.

Anaerobic bacterial infections: adults - 200-400 mg 2-3 times a day; children - 7 mg / kg every 8 hours. The course of treatment is 7-10 days;

For the prevention of anaerobic infection before surgery on the pelvic organs and the large intestine, a single oral dose of 1000 mg is prescribed, then 200 mg 3 times a day.

In combination with amoxicillin (2.25 g / day), the daily dose of metronidazole is 1.5 g, the frequency of administration is 3 times a day.

For patients with severe impaired liver and kidney function, the daily dose of metronidazole is 1 g, amoxicillin is 1.5 g. The frequency of admission is 2 times a day.

Gel

For outdoor use. The gel is applied to previously cleansed affected areas of the skin with a thin layer 2 times a day, morning and evening, for 3-9 weeks.

The duration of treatment is 3-4 months, the therapeutic effect is usually noted after 3 weeks of treatment.

Candles

Gel Metrogil Denta

The drug is intended only for use in dental practice.

For adults and children over 6 years of age with gingivitis, Metrogyl Denta is applied to the gum area 2 times a day with a thin layer (with a finger or with a cotton swab), it is not recommended to wash off the gel. The duration of the course of therapy is on average 7-10 days. After applying the gel, you should refrain from drinking and eating for 30 minutes.

In case of periodontitis, after removal of dental deposits, periodontal pockets are treated with the preparation and the gel is applied to the gum area. Exposure time - 30 min. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel on his own: the drug should be applied to the gum area 2 times a day for 7-10 days.

With aphthous stomatitis, the gel is applied to the affected area of ​​the oral mucosa 2 times a day for 7-10 days.

To prevent exacerbations of chronic gingivitis and periodontitis, the gel is applied to the gum area 2 times a day for 7-10 days. Preventive courses are held 2-3 times a year.

To prevent post-extraction alveolitis, the well is treated with the drug after tooth extraction, then the gel is used on an outpatient basis 2-3 times a day for 7-10 days.

Side effect

• dry mouth;
• nausea, vomiting;
• constipation, diarrhea;
• pseudomembranous colitis;
• intestinal colic;
• glossitis, stomatitis;
• lack of appetite;
• unpleasant metallic taste in the mouth;
• headache;
• dizziness;
• disturbance of consciousness;
• increased excitability;
• depression;
• sleep disturbance;
• weakness;
• epileptic seizures;
• peripheral neuropathy;
• impaired coordination of movements;
• hallucinations;
• burning sensation in the urethra;
• fungal flora of the vagina (candidiasis);
• reddish-brown urine;
• urinary incontinence;
• nasal congestion;
• skin hyperemia;
• skin rash;
• hives;
• fever;
• anaphylactic shock;
• leukopenia, thrombocytopenia.

Contraindications

• organic lesions of the central nervous system (including epilepsy);
• blood diseases (including history);
• liver failure (in the case of high doses);
• 1 trimester of pregnancy;
• children's age (up to 12 years);
• hypersensitivity to metronidazole or the components that make up the drug, as well as to other nitroimidazole derivatives.

Use during pregnancy and lactation

2nd and 3rd trimesters of pregnancy - only for health reasons; lactating mothers - according to indications, with the simultaneous termination of breastfeeding

special instructions

While taking the drug, you can not drink alcohol (possible development of a disulfiram-like reaction: spastic abdominal pain, nausea, vomiting, headache, sudden flushing of the face). Metronidazole is used to treat alcoholism and pathological cravings for alcohol.

With leukopenia, the possibility of continuing treatment depends on the risk of developing an infectious process.

Long-term administration of the drug is desirable to carry out under the control of peripheral blood parameters.

The appearance of ataxia, dizziness and any other deterioration in the neurological status of patients requires discontinuation of treatment.

May immobilize treponema and lead to a false positive Nelson test.

In the treatment of trichomonas vaginitis in women and trichomonas urethritis in men, it is necessary to refrain from sexual activity. Mandatory simultaneous treatment of sexual partners. Treatment does not stop during menstruation. After therapy for trichomoniasis, control tests should be carried out for 3 regular cycles before and after menstruation.

After treatment of giardiasis, if symptoms persist, after 3-4 weeks, perform 3 stool tests at intervals of several days (in some well-treated patients, lactose intolerance caused by invasion may persist for several weeks or months, resembling the symptoms of giardiasis).

drug interaction

Metronidazole enhances the effect of indirect anticoagulants, which leads to an increase in the time of prothrombin formation.

Similar to disulfiram, it can cause ethanol intolerance.

Cimetidine inhibits the metabolism of metronidazole, which can lead to an increase in its concentration in the blood serum and an increase in the risk of side effects.

Sulfonamides enhance the antimicrobial effect of metronidazole.

The simultaneous administration of drugs that stimulate microsomal oxidation enzymes in the liver (phenobarbital, phenytoin) can accelerate the elimination of metronidazole, resulting in a decrease in its plasma concentration.

In patients receiving long-term treatment with lithium preparations in high doses, when taking metronidazole, an increase in the concentration of lithium in the blood plasma and the development of symptoms of intoxication may occur.

Analogues of the drug Metrogyl

Structural analogues for the active substance:

• Bacimex;
• Dentamet;
• Deflamont;
• Klion;
• Metrovagin;
• Metroxan;
• Metrolacare;
• Metron;
• Metronidazole;
• Metronidazole Nycomed;
• Metronidal;
• Metroseptol;
• Orvagil;
• Rozamet;
• Rosex;
• Siptrogil;
• Tricho-PIN;
• Trichobrol;
• Trichopolum;
• Trichosept;
• Flagyl;
• Efloran.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.

Let's take a closer look at the gel for gums Metrogyl Denta. Its instructions for use, price, reviews - all this is of great interest to people who periodically suffer from various periodontal diseases.

Dentists often prescribe Metrogyl Denta to patients with a variety of problems, as this gel is an excellent antiseptic and helps to cope with a variety of pathogens.

Compound

The successful use of the ointment is due to its qualitative composition. And this:

1. Metronidazole benzoate is a good antibacterial agent. It perfectly penetrates into saliva and increases the protection of the oral cavity from pathogens.
2. Digluconate solution is another antiseptic that acts against herpes viruses, protozoa, most bacteria and cleanses the mucosa from pus.
3. Additional substances - water base, levomenthol, saccharin, propylene glycol, disodium edetate, sodium hydroxide, carbomer-940.

The action of the drug

The effectiveness of the treatment is ensured by the active action of each component of the gel. The combination of antiseptics acts on a wide range of bacteria - gram-positive and gram-negative, anaerobic, many viruses and yeast spores. The only thing that Metrogil Denta is powerless against is active lactobacilli.

Thanks to this, with the help of Metrogyl Denta gel, you can disinfect the oral cavity, cure gum inflammation, remove ulcers and help in the treatment of many local infections.

Indications for use

The most effective gel will be in such diseases:

• pulpitis (and);
• , even in acute form;
• periodontal abscess;
• healing of gum injury;
• ulcerative necrotic gingivitis, otherwise Vincent's gingivitis;
• peritonsillar abscess;
• juvenile periodontitis.

Doctors sometimes prescribe the drug even with normal bleeding gums or wisdom teeth. After all, it helps to reduce pain and cleanses the oral cavity.

Metrogyl Denta for gums and instructions for its use

The patient must apply the drug to the gums on their own. But for the first time, it is necessary for the doctor to make the application and teach how to properly apply the gel to the damaged gum. There are the following recommendations in this regard:

• The gel is applied once a day, unless the doctor has prescribed more frequent use. Within half an hour after this, it is advisable not to rinse your mouth, do not eat or drink.
• The average course of treatment usually lasts a week or ten days. If the dentist has prescribed a longer treatment, then you should follow his recommendation.
• In the treatment of periodontitis, the cleaned dental canals are treated with a gel in the form of applications. At the same time, they need to be applied for 30 minutes twice a day.
• If the patient has chronic gingivitis, then not even in the acute stage, for the purpose of prevention, the same applications are made twice a day.
• After tooth extraction, Therefore, in order to disinfect and relieve inflammation, it is recommended to treat this place with Metrogil Dent gel two or even three times a day. The course of prevention also lasts up to 10 days.
• In order to prevent other diseases of the oral cavity, some dentists recommend doing periodic finger gum massage with gel for about two to three minutes immediately after brushing your teeth. After such a massage, simply spit out the remnants of saliva with the medicine and do not rinse your mouth.
• If the patient experiences exacerbations of catarrhal gingivitis or generalized periodontitis, then for the prevention of such gum massage with Metrogyl Denta, it is recommended to carry out twice a day. After the massage, you should not rinse your mouth, drink or eat for another hour. Such prophylaxis lasts about two weeks and is carried out 2-3 times a year.

Contraindications and side effects

Restrictions on the use of Metrogil Dent are small, but they exist. Do not use the gel in the following cases:

1. Hypersensitivity to the components of the drug, especially to metronidazole or chlorhexidine.
2. Children under 14 years old.
3. Pregnancy and lactation.

In any case, it is not worth prescribing such treatment on your own. The use of Metrogyl Dent, its frequency and duration of treatment is prescribed only by an experienced dentist.

In some cases, after using the gel, side effects may occur:

• metallic taste in the mouth;
• headache;
• burning or itching of the gums;
• allergy;
• stomach upset;
• nausea;
• dizziness;
• convulsions.

Cases of such reactions are rare, and may occur, rather, with accidental ingestion of the drug. An overdose of a therapeutic agent with proper use is practically excluded.

Analogues

If you are not satisfied with the relatively high price of the drug, then by the main components you can find cheaper analogues of the drug. It could be:

1. Metrodent gel.
2. Dentagel.
3. Metroviol Denta.
4. Metrohex gel.
5. Stomato-Gel and others.

Video: promo video about Metrogil Denta (in English).